Trends in Medical Research - Current Issue

Evaluation of Biplane Double Supported Screw Fixation of Femoral Neck Fracture: A Longitudinal Study at a Tertiary Health Care Center in Manipur

10 June, 2026

Background: Various treatment modalities for treating fracture neck of femur have been described. But complications like insufficient reduction, unstable fixation and avascular necrosis of head have been reported with almost all the fixation techniques. Objective: To evaluate and assess the clinical and functional outcomes of biplane double supported screw fixation for managing femoral neck fracture using Harris Hip Score. Materials and Methods: A hospital-based longitudinal study was taken up in the Department of Orthopaedics RIMS, Imphal, Manipur during the period August, 2018 to July, 2020. All the patients admitted in RIMS Hospital with fracture neck of femur medically fit for surgery during the study period were included except those who are not medically fit for surgery and not willing to participate. Under standard surgical precautions, biplane double supported screw fixation was performed with 3 cannulated screws. Patients were followed for a minimum of 6 months to assess the outcome using Harris Hip Score. Results: Forty seven patients could be followed up-to 6 months. There was no significant blood loss during the surgery. After 6 months of the surgery radiological union was seen in 39 (83%) patients. At the end of 3 months the Harris Hip Score was not that encouraging but at the end of 6 months 40% had excellent score, 36% good score, 13% fair score and the remaining 11% had bad score. The difference in the scores at 3 and 6 months was found to be statistically significant. Conclusion: Management of femoral neck fracture with Biplane Double-Supported Screw Fixation provides good clinical and functional outcomes. BDSF is a surgical technique which should be offered to the patients with fracture neck femur before contemplating total or hemiarthroplasty of hip.

Clinical, Angiographic Profile and Immediate Outcome of COVID-19 Patients Presenting as Acute Coronary Syndrome: An Observational Study

10 June, 2026

Background: COVID-19 pandemic has involved around 213 countries and affected around 33 million people worldwide and around 6.2 million in India with about 1 million deaths worldwide. Lockdown was enforced in India as in other parts of the world to contain the spread of COVID-19 pandemic. However, it resulted in decreased hospitalization for acute coronary syndrome, delayed presentation and change in decision making. The main aim of our study was to analyze the presenting pattern and outcome of COVID-19 patients. Materials and Methods: In this study, done at tertiary care centre, patients of acute coronary syndrome over last 4 months underwent RT-PCR for SARS-CoV-2 and HRCT chest prior to admission. A total of 25 (5.8%) patients with acute coronary syndrome who had evidence of COVID-19 infection were enrolled in the study. This group was evaluated for the risk factors, presenting symptoms, killip class, type of acute coronary syndrome (STEMI vs NSTEMI), time to presentation to hospital, treatment received (medical management/thrombolysis/PCI/CABG), cardiac arrhythmias, mean ejection fraction, HRCT chest (CORADS grading), any complications and immediate outcome. Results: In this study group, mean age of presentation was 50.9+12.8 years involving predominantly males (72%). Hypertension was present in 11(44%), diabetes in 7 (28%), smoking in 8 (32%) and obesity in 5 (20%) patients, respectively. The main presenting symptom was only chest pain in 20 (80%) patients followed by chest pain and dyspnea in 4 (16%) patients. Fever was present at the time of presentation in only 8 (32%) patients. Most common presentation was STEMI (84%). Only 5 patients (23.8%) in the STEMI group presented to the hospital within the window period. Around 60% patients presented with killip class I, 4 patients had cardiac arrhythmias (first degree heart block, 2:1 AV block, atrial fibrillation and ventricular tachycardia). Mean ejection fraction of our study group was 40.6+8.9. Most common finding on HRCT chest was CORADS 5 (40%) followed by CORADS 4 (24%). Coronary angiogram was done in 4 (16%) patients who had persistent chest pain and intervention was attempted/done in 3 of these patients. Around 7 (28%) patients had complications which included acute kidney injury in 1 patient, multiorgan dysfunction (MODS) in 3 patients out of which 2 patients died, ischemic hepatitis in 1 patient, lower limb DVT in 1 patient and DVT with pulmonary thromboembolism in 1 patient. Both the expired patients belonged to the nonintervention arm. Conclusion: In this study, 5.8% patients of acute coronary syndrome had evidence of COVID-19 infection. Most of these patients had delayed presentation to the hospital, a less of interventional strategy and more of conservative management was instituted. Intervention was done/attempted in 4 patients who had persistent chest pain. Complications developed in 24% of the patients with a mortality of 8%. The expired patients belonged to the nonintervention arm and had multiorgan dysfunction.

Compliance to Iron-Folic Acid Supplementation among Pregnant Muslim Women in Imphal, Manipur, India: A Cross-Sectional Study

10 June, 2026

Background: Intermittent Iron and Folic Acid Supplementation (IFAS) is advised in areas where the prevalence of anaemia among pregnant women is ≥20%. Effectiveness and successful interventions of national strategy will depend on compliance to IFAS. This study was conducted to determine the proportion of antenatal mothers compliant to Iron-folic acid supplementation and to identify the factors influencing it. Objective: The current study was conducted to determine the proportion of antenatal mothers non-compliant to IFAS and also to identify the factors affecting it. Materials and Methods: A cross-sectional study among pregnant women attending ante-natal clinic was done from September, 2020 to February, 2021 at an Urban Primary Health Centre, Imphal East District. Patients aged ≥18 years, completed 12 weeks of pregnancy and started IFAS were consecutively enrolled according to OPD registration list and interviewed using a pre-tested questionnaire. Logistic regression was performed for determining association between selected variables, taking p<0.05 for statistical significance. Results: Out of 142 women participated in the study, 97 (68%) were compliant to IFAS. Women who were multigravida (AOR: 0.14; 95% CI: 0.038-0.48), self-purchased IFAS (AOR: 0.16; 95% CI: 0.054-0.47) were found to be less likely to be compliant to IFAS. Women of good knowledge score (AOR: 6.4; 95% CI: 1.7-23.8) regarding anaemia and IFAS were more likely to be compliant. Conclusion: Almost one-third of participants (91; 64.1%) were compliant to IFAS and it was associated with better knowledge. Being employee, multigravida and having purchased IFA by self were negatively associated with compliance. IFAS. There is a need to scale up health awareness on IFAS and Ante Natal Care coverage of antenatal IFAS supply through community level workers.

Assessment of the Haemodynamic Effect of Adrenaline in Septoplasty Procedure

10 June, 2026

Background: The present study aims to assess the haemodynamic effect of adrenaline in septoplasty procedure. Materials and Methods: One hundred ten adult patients in age ranged 20-40 years of either sex were classified them into 2 groups, each containing 55 patients. Group A patients were administered infiltration of 2% lignocaine with 1:100,000 adrenaline and in group B, 2% lignocaine with topical 1:100,000 adrenaline was used. Parameters such as heart rate, blood pressure, blood loss and pain (VAS) was recorded in both groups. Results: Mean age in group A was 34.5 years and in group B was 38.2 years, weight was 72.4 kg in group A and 72.8 kg in group B. In group A, pre-anaesthetic systolic blood pressure was 120.6 and in group B was 118.4. The mean pre-operative heart rate (beats/min) was 79.8 in group A and 78.2 in group B, 1st heart rate was 81.2 in group A and 75.2 in group B, 5th heart rate was 78.6 in group A and 73.6 in group B and 10th heart rate was 74.2 in group A and 72.5 in group B. VAS score at 1 hr was 6 in group A and 5 group B, at 2 hrs was 7.2 and 6, at 6 hrs was 8.5 and 7, at 12 hrs was 7 and 8 and at 24 hrs was 8 in group A and 9 in group B. In group A, procedure time was 36.4 min and in group II was 40.2 min, blood loss was 50.6 mL in group A and 72.4 mL in group B and partial oxygen pressure was 99% in both groups. Conclusion: There was no difference in haemodynamic in both groups, hence, there is no need to use topical adrenaline in septoplasty patients.

To Evaluate the Awareness and Prevention of Osteoporosis in Patients Attending Orthopaedics Outdoor Clinics in a Tertiary Level Hospital

10 June, 2026

Background: Purpose of this study was to assess the mindfulness about osteoporosis in patients visiting orthopedic outdoor department. Osteoporosis is known as a "Silent disease predominant among older population. Materials and Methods: This study was done between March to August, 2021 in All India Institute of Medical Sciences, Rishikesh among Orthopedic OPD patients, chosen by comfort Sampling Technique. A self-directed and pre-tested survey was ready to gather data about mindfulness in these patients and information was analyzed utilizing Excel software and programming utilizing suitable statistical tests. Results: In current study, larger parts of patients were over 40 years about 68% (340) and 32% (160) of the patients were under 40 years old. Males were about 54% (270) and 46% (230) were female having M: F proportion of 1.17. Among the total patients, 235 (47%) have absence of mindfulness about risk components of osteoporosis. 225 (45%) had communicated about inadequate measures of dietary calcium, which is trailed by physical inactivity in 225 (45%) and low vitamin D intake by 272 (54.5%). About 240 (48%) know the danger of eating less calcium-rich food varieties, trailed by calcium and vitamin D enhancements by 210 (42%) and getting vitamin D by sunlight exposure by 175 (38.5%) helps in forestalling osteoporosis. 235 (47%) patients didn't think about the preventive variables of osteoporosis. Conclusion: According to this study, larger part of patients' needs mindfulness about the danger just as preventive variables of osteoporosis.