https://scialert.net European Journal of Dentistry and Medicine en-us Science Alert Wed, 10 Jun 2026 18:11:57 +0200 Wed, 10 Jun 2026 18:14:14 +0200 RssPublisher 0.2.0 beta https://scialert.net/images/logo.gif https://scialert.net 41 233 European Journal of Dentistry and Medicine Anticariogenic Activity of Some Indian Traditional Medicinal Plants Background and Objective: Today, dental caries is still one of the most common diseases in the world. The causes of tooth decay in most cases are the poor oral hygiene and high sugar consumption. Despite several dental caries agents being available in the market, the search for an effective agent still continues. Several undesirable side effects associated with these agents stimulated the search for alternate agents. The objective of this study was than to investigate the inhibitory effect of the crude seed extracts from some traditional medicinal plants on anticariogenic organisms under in vitro condition for their use for controlling dental caries. Attempt was also made to characterize bioactive compound at primary level. Materials and Methods: The anticariogenic activity was assessed by agar well diffusion method. MIC against six dental microorganisms and the radial zone of inhibition was measured. Phytochemical evaluation of all the selected plants showed good MIC values and TLC-Bioautography. The data was statistically analyzed by one way analysis of variance (ANOVA) using SPSS ver. 16.0. Results: The results revealed that the hexane extract of plant seeds has more potent anticariogenic activities against oral microorganisms. Maximum zone of inhibition (18 mm) was found when seed extracts of Mimusops elengi L. tested against Candida albicans. The MIC of hexane extract of Mimusops elengi L. and Punica granatum L. seed against CA and SP was 0.075 and 0.3, respectively. The MIC value of 0.3 was found for SP using Punica granatum L. The result of bioautography showed that the compound was active against Candida albicans and Streptococcus pyogenes. Conclusion: Hence, the study concludes that the very good activity of methanol extract of seed of Mimusops elengi L. and Punica granatum L. will be useful in the future development of effective toothpaste or mouth washer against oral microorganisms.]]> https://scialert.net/abstract/?doi=ejdm.2017.1.8 10 June, 2026