alternative natural medical treatments

GLUTATHIONE, THE MASTER ANTIOXIDANT

2010-01-07T15:59:00.000-08:00

More Energy & Better Health

As we age, and expose our bodies to stress, chemicals, pollutants, and average lifestyle habits, we begin to lose energy, vitality, mental alertness, and more.

Most of us are aware that there are consequences for our actions; however the danger lies in the fallacy of believing that you will start taking better care of yourself “tomorrow.”

Dr. Robert H. Keller, one of the world’s leading scientists, dedicated 10 years of research and development in creating MaxGXL to assist the world in its quest for a higher level of health.

The MaxGXL Story

The Breakthrough

In 1994, Dr. Robert H. Keller founded The BIODORON Institute of Advanced Medicine, a state-of-the-art medical clinic specializing in cutting-edge treatment for immune system disorders and anti-aging.

After reviewing subject lab results for years, Dr. Keller noticed a trend. He kept seeing significantly low levels of uric acid in subjects with immune disorders. He decided to explore this finding, and his initial research concluded that uric acid is the last antioxidant at the body’s disposal when all the normal antioxidants have been exhausted.

As Dr. Keller has always been a strong advocate of nutrition, he went back in the literature, seeking the answer to one question: If uric acid is the body’s last defense, then what is the first? His investigation led him to a substance called glutathione.

Glutathione (GSH): The Master Antioxidant

Dr. Keller discovered that the most prevalent, powerful and multifunctional antioxidant in the human body – employed by every organ – is glutathione.

Glutathione (GSH) is a small protein produced naturally in our cells if the requisite precursors are present. It functions both as an antioxidant and an antitoxin and is a major defense system against illness and aging. Our glutathione level actually indicates our state of health and can predict longevity. It has been suggested that in the future, GSH levels will be closely monitored. There are over 70,000 medical articles currently published on GSH, yet most health professionals have only a vague idea of its significance. In the near future, the importance of glutathione will be widely recognized.

The Test

After learning of the importance of GSH, Dr. Keller needed to test the hypothesis that the levels of GSH in subjects with immune disorders were, in fact, severely diminished. To get a current and accurate gauge of a subject’s GSH level, Dr. Keller knew the test must measure GSH inside of lymphocytes (white blood cells); however, no such lab test existed.

Using a state-of-the-art medical laboratory, Dr. Keller and his team of scientists developed a proprietary lab test to measure levels of GSH inside the lymphocytes.

The tests confirmed the hypothesis. People who are stressed, aging, lacking sleep, or with any prolonged illness utilize glutathione at an accelerated rate resulting in decreased bodily stores, weakened defenses, and increased risk of illnesses including accelerated aging.

The Challenge

It was clear that the GSH (Glutathione) levels needed to be replenished in these subjects. But how? Glutathione is produced naturally from three amino acids: glycine, glutamine, and cysteine. These essential precursors of GSH must be able to make it from the mouth to the gut, then through the cells walls and subsequently the mitochondrial membrane.

Therein lies the challenge.

Unfortunately, we can’t raise our body’s GSH level with ordinary foods or pure L-glutathione. Even though glutathione is present in many fruits, vegetables and meats, this protein is instantly broken down during digestion into its three amino acids. Cysteine, or N-acetylcysteine (NAC), is the most important of these precursors and is the main limiting factor necessary for the body to manufacture GSH. Alone in the gut after digestion, cysteine is treated as a free radical and rapidly oxidized. Consequently, only a very small percentage reaches our bloodstream and cells.

Furthermore, GSH is always in great demand and is rapidly consumed, so any GSH that is made will be used up quickly making it even more difficult to increase this level.

So what can MaxGXL do for you?

MaxGXL’s Patented Formula Dramatically Increases Intracellular GSH

MaxGXL provides the proper nutrients needed to promote the body’s own ability to manufacture and absorb glutathione. MaxGXL also aids in liver support, thus helping the liver to function as the main production site and storehouse for glutathione.

The graph below shows the increase in glutathione levels experienced by 4 groups of people. Group 1 was tested after 6 months of use, while Groups 2, 3, and 4 were tested after only 3 months of theMaxGXL regimen.

The data indicate MaxGXL’s effectiveness in those who are stressed, aging, lacking sleep, or with any prolonged illness. In these situations, MaxGXL stimulates the body’s production of glutathione to compensate for the body’s accelerated use of it, strengthening your natural defenses, decreasing your risk of illness, and guarding against the effects of the body’s aging process.

Increasing Age and Other Factors Reduce the Body’s Production and Utilization of GSH.

Research has shown that individuals who have low levels of glutathione are susceptible to chronic illness. Research shows that GSH levels decline by 8% to 12% per decade, beginning at the age of 20. Levels of glutathione are further reduced by continual stress upon the immune system such as illness, infection, and environmental toxins. As we now know, a lowered immune system can bring about illness and disease. This is a ferocious cycle. While you need glutathione for a productive immune system, a weakened immune system hampers the production of glutathione.

More Energy	Constant free radical damage overwhelms cellular energy production. Increased stress, unwise food choices, and the lack of quality sleep are other agents that damage cells and drain energy. Glutathione optimizes energy production inside every cell in your body by extinguishing free radicals and restoring cell quality.
Immune System	Immune system cells need glutathione to function properly. Your body’s immune system arsenal of T-cells, B-cells, and white blood cells (lymphocytes) need glutathione to perform at an optimum level.
Cellular Detox	The human body is under contstant attack. In today’s polluted world, toxins are found in food, water, and the air. Glutathione is one of the principle components to neutralize and dispose of these toxins. If your body lacks glutathione it is unable to detoxify itself. Your immune system, endocrine, and nervous system all become imbalanced, which in turn can lead to many health challenges.
Peak Athletic Performance	Glutahione plays a principle role in creating energy and helping your body utilize oxygen. Abundant glutathione levels allow your body to recover faster following strenuous exercise and neutralize free radical production that occurs naturally from exercising. The quicker you can recover from exertion, the quicker you can return to activity. Glutathione can serve as a keystone to your athletic success.
Fight Cellular Inflammation	Uncontrolled inflammation is at the root of most major health issues ranging from heart conditions to joint and muscular discomfort. Glutahione offsets the effects of inflammation at the cellular level. Because glutathione is present in every cell of the human body, it can regulate inflammation throughout the body.

Remember the Important Roles of Glutathione:

Fights against oxidative cell damage (from free radicals)
Protein Synthesis
Amino Acid transport
Cellular detoxification
Immune system enhancement
Enzyme activation
Fights Inflammation
ATP (energy) production

2009-12-24T18:55:00.000-08:00

Glutathione is a small molecule found in almost every cell. It cannot enter most cells directly and therefore must be made inside the cell, from its three constituent amino acids: glycine, glutamate and cysteine. The rate at which glutathione can be made depends on the availability of cysteine, which is relatively scarce in foodstuffs. Furthermore, the cysteine molecule has a sulfur-containing portion which gives the whole glutathione molecule its biochemical activity, i.e. its ability to carry out the following vitally important functions:

Firstly, glutathione is the major antioxidant produced by the cell, protecting it from free radicals(oxygen radicals,oxyradicals). These highly reactive substances, if left unchecked, will damage or destroy key cell components (e.g. membranes, DNA) in microseconds. Oxyradicals are generated in the many thousand mitochondria located inside each cell, where nutrients like glucose are burnt using oxygen to make energy. (Mitochondria can be thought of as the batteries that provide the power for the cells to operate).

Oxyradicals also come from pollutants, from UV radiation and other sources. In addition, glutathione recycles other well-known antioxidants such as vitamin C and vitamin E, keeping them in their active state.

Secondly, glutathione is a very important detoxifying agent, enabling the body to get rid of undesirable toxins and pollutants. It forms a soluble compound with the toxin that can then be excreted through the urine or the gut. The liver and kidneys contain high levels of glutathione as they have the greatest exposure to toxins. The lungs are also rich in glutathione partly for the same reason.

Many cancer-producing chemicals, heavy metals, drug metabolites etc. are disposed of in this way.

Thirdly, glutathione plays a crucial role in maintaining a normal balance between oxidation and anti-oxidation. This, in turn, regulates many of the cell's vital functions, such as the synthesis and repair of DNA, the synthesis of proteins and the activation and regulation of enzymes.

Fourthly, glutathione is required in many of the intricate steps needed to carry out an immune response. For example, it is needed for the lymphocytes to multiply in order to develop a strong immune response, and for killer lymphocytes to be able to kill undesirable cells such as cancer cells or virally infected cells. The importance of glutathione cannot be overstated. It has multiple roles as indicated and, indeed, as one examines each system or organ more closely, the necessity for glutathione becomes increasingly evident.

Glutathione values decline with age and higher values in older people are seen to correlate with better health, underscoring the importance of this remarkable substance for maintaining a healthy, well-functioning body.

2009-12-18T21:17:00.001-08:00

Glutathione is the Master Antioxidant

Glutathione is your body's master antioxidant and one of the most important cleansing and healing agents.Glutathione blocks free radical damage and helps to recycle Vitamins E and C, therefore plays a key role in their function. Because Glutathione exists within the cells, it is in a prime position to neutralize free radicals. The highest concentration of glutathione is found in the liver which is the principal organ involved in the detoxification and elimination of toxic materials.

Glutathione may also help with detoxification by binding to toxins such as heavy metals, solvents and pesticides, allowing them to be excreted in urine or bile.

Glutathione is a "Superfood"

Glutathione is one of the 14 Superfoods listed in "SuperFoods Rx : Fourteen Foods That Will Change Your Life", co-authored by Dr. S. Pratt, an authority on food and aging.

The list is based on an exhaustive study of the scientific research behind the world's best daily diets, and includes the 14 nutrients that show up consistently in the most health-promoting, disease-preventing, anti-aging diets in the world.

2009-12-15T19:24:00.000-08:00

About MaxGXL

MaxGXL increases Glutathione in your body which increases energy, strengthens your immune system, and promotes longevity. MaxGXL has been awarded a patent because it is so unique in how it dramatically increases Glutathione, a major component of every living cell in your body. Want to be healthier, have more energy, feel better, and live longer? Increasing your Glutahione level in your body with MaxGXL will detoxify your body and strengthen your immune system.

MaxGXL and Glutathione, the Master Antioxidant

The world's most powerful antioxidant is not a berry, fruit, or a drink - it's in your body! It's called glutathione (GSH), and every cell in your body requires an adequate supply of Glutathione to function and stay healthy. MaxGXL increases Glutathione levels in your body.

When we are in our 20s our body produces normal levels of glutathione, but as we age and approach our thirties and beyond our body's production of this powerful disease fighting compound slows to a trickle. Without adequate glutathione in our body we develop diseases and we are prone to a multitude of medical disorders. MaxGXL restores your glutathione levels which helps to prevent the diseases associated with aging.

MaxGXL Increases Glutathione Levels 292%

MaxGXL has been clinically proven in a double-blind, cross-over study to raise Glutathionelevels by 292%and to increase the Human Growth Hormone markers DHEA and IGF-1 by 40% (average clinical results). Low Glutathione levels result in illnesses, infections, and inflammation. Glutathione is your body's first line of defense against the diseases of aging, harmful effects of emotional and medical stresses, overexertion, pain, toxins, and low energy.

Low levels of Glutathione are linked to cancer, high blood pressure, heart disease, diabetes, premature aging, arthritis, chronic fatigue syndrome, lupus, stroke, asthma, Parkinson's disease, Alzheimer's, dementia, multiple sclerosis (MS), schizophrenia, Down Syndrome, diseases of the liver, sleep deprivation, and others. MaxGXL increases Glutathione in your body to help prevent and fight these medical disorders.

Alan Pressman, DC, Phd, CNN, wrote in his book Glutathione: The Ultimate Antioxidant, "When your Glutathione level is high, your overall health is high. You feel good and look good. You fight off illnesses quickly, you have plenty of energy, and you feel mentally and physically alert."

Discovered by Dr. Robert Keller

The MaxGXL Glutathione formula was discovered by Dr. Robert Keller, who was recently namedone of the World's 2,000 Most Outstanding Scientist of the 21st Century. Dr. Keller is a world renowned doctor withnumerous achievements, including serving on the review panel of the National Institutes of Health, the VA, the faculties of the Mayo Graduate School of Medicine, and others. Dr. Keller, MD, MS, FACP, AAHIV is a Board Certified Immunologist, Hematologist and Oncologist. He was elected to the Board of Governors of the American Academy of HIV Medicine, and nominated as "Top Physician" for 2003, 2004, 2005, 2006, and 2007 in the fields of Internal Medicine, Immunology, and Hematology.

5 Ways MaxGXL Can Improve Your Life

More Energy - Constant free radical damage overwhelms cellular energy production. Increased stress, unwise food choices, and the lack of quality sleep are other agents that damage cells and drain energy. Glutathione optimizes energy production inside every cell in your body by extinguishing free radicals and restoring cell quality.
Immune System - Immune system cells need glutathione to function properly. Your body's immune system arsenal of T-cells, B-cells, and white blood cells (lymphocytes) need glutathione to perform at an optimum level.
Cellular Detox - The human body is under contstant attack. In today's polluted world, toxins are found in food, water, and the air. Glutathione is one of the principle components to neutralize and dispose of these toxins. If your body lacks glutathione it is unable to detoxify itself. Your immune system, endocrine, and nervous system all become imbalanced, which in turn can lead to many health challenges.
Peak Athletic Performance - Glutahione plays a principle role in creating energy and helping your body utilize oxygen. Abundant glutathione levels allow your body to recover faster following strenuous exercise and neutralize free radical production that occurs naturally from exercising. The quicker you can recover from exertion, the quicker you can return to activity. Glutathione can serve as a keystone to your athletic success.
Fight Cellular Inflammation - Uncontrolled inflammation is at the root of most major health issues ranging from heart conditions to joint and muscular discomfort. Glutahione offsets the effects of inflammation at the cellular level. Because glutathione is present in every cell of the human body, it can regulate inflammation throughout the body.

MaxGXL and Living Longer

Recent studies document that centenarians have significantly high levels of Glutathione. Researchers at a University in Denmark have found that centenarians in the age group of 100 to 105 years of age exhibit a high activity of Glutathione in their red blood cells. In this study, centenarians having the best cognitive and physical functional capacity tended to have the highest activity of Glutathione.

2009-12-13T19:18:00.001-08:00

person to professional athlete.

MaxGXL Sport carries the prestigious NSF Certified for Sport™certification to ensure the product is free from substances on the banned substances list. Ideal for everyone from professional athletes to the average person, it contains the same ingredients as regularMaxGXL, only packaged using veggie caps and sealed in a convenient bottle.

2009-12-08T18:26:00.000-08:00

Obtaining the nutrients your body needs for optimal performance is an increasingly difficult challenge. Soils are depleted of vital trace elements; factory farming practices and over processing further reduce the nutrients available from food. Vitamin and mineral supplements have long been the solution but they are not always absorbed. If you feel like half of your 'cylinders' are not firing, help is on the way! Max N-Fuze is all about effectively delivering the nutrients you need.

Decades ago, simply taking dietary supplements was accepted as a novel way to give your body what it needs.

Due to the advances of science, we now know that just because you take a dietary supplement does not mean that your cells are efficiently absorbing the nutrients.

Consequently, there has been a long-standing quest to discover a legitimate breakthrough technology that would allow efficient and maximum cellular absorption of nutrient-sized particles.

Max N-Fuze uses a patent-pending nanotechnology to efficiently deliver targeted nutrients that are capable of readily being absorbed and utilized by the cell. This breakthrough technology consists of enveloping nano-sized nutrients in a highly purified water cluster and efficiently delivering the nano-sized particle to the cell.

Max N-Fuze was subjected to vigorous safety testing at Clemson University. Additionally, Max International is a member of the Institute of Nutraceutical Research (INR). The INR is a leading research group that consolidates the intellectual and physical resources of the faculty at Clemson University and links these resources to South Carolina Nutrition Research Consortium (SCNRC) involving the South Carolina Research Authority, the University of South Carolina and the Medical University of SC in a unique partnership.

Max N-Fuze™...

Supports the production and function of superoxide dismutase (SOD) and catalase (CAT), two vital antioxidants produced by the body to fight the potent free radical superoxide.*

Provides needed nutrients to further optimize glutathione (GSH) production.*
Delivers vitamins, minerals, and herbal ingredients to support optimal cell function, cellular communication and cellular defense mechanisms.*
Delivers targeted nutrients needed to support leptin sensitivity.*
Contains D-ribose and CoQ10 to support ATP (energy) production and function.*
Utilizes patent-pending nanotechnology designed to maximize absorption.*

What Is...

Superoxide Dismutase (SOD) Superoxide dismutase (SOD) is an enzyme that removes the superoxide (O2-) radical. We hear a lot in nutritional news about "antioxidants". Think of SOD as a natural antioxidant. Since cancer cells produce more oxidants than normal cells, they can basically oxidize themselves to death. That is why SOD is a target protein -- if SOD is inhibited in the cancer cell, the cancer cells are damaged, controlling growth.

Catalase (CAT) Catalase is a common enzyme found in nearly all living organisms, where it functions to catalyze the decomposition of hydrogen peroxide to water and oxygen. Catalase has one of the highest turnover rates of all enzymes; one molecule of catalase can convert millions of molecules of hydrogen peroxide to water and oxygen per second. Catalase is a tetramer of four polypeptide chains, each over 500 amino acids long. It contains four porphyrin heme (iron) groups that allow the enzyme to react with the hydrogen peroxide. The optimum pH for catalase is approximately 7, while the optimum temperature varies by species.

2009-12-01T12:25:00.000-08:00

It's a known fact, everyone wants to live a longer and happier life. And really, all that is required to achieve this is to have a healthy mind and a healthy body. A healthy body is one which is full of energy, good immunity and a great detoxification system. I'm sure you agree, you need to have all the three for the best results. However something that you may not know is one nutrient specifically plays an important role in providing all three of these, and it is known as 'Glutathione'. Your body itself synthesizes this vital nutrient and all you have to do is to support your body ability to produce glutathione in adequate amounts.

Glutathione - the anti-oxidant and free radicals

Our body undergoes wear and tear continuously. It is exposed to so many harmful things. It is exposed to stress, pollution, radiation, infection, drugs, poor diet, aging, injury, trauma etc. All these pile up a dangerous group of chemicals called free radicals. These get accumulated in the cells. These free radicals meddle with the normal functioning of the cells.

Free radicals need to be removed if your bodies cells are to function normally. This is where anti-oxidants play a major role. They neutralize these free radicals and prevent them from causing further damage to the cells. Glutathione is the super anti-oxidant that is present inside the cell itself. It is present in all cells and efficiently nullifies the effects of free radicals. The incredible thing is that Glutathione is produced naturally in our body. However as we age we produce less and less, eventually allowing free radicals to run freely in our body. Creating disease and other problems we call, "the signs of aging"

Glutathione and immunity

A weak immune system is helpless in preventing various infections. If your immune system is low, for example if you have an HIV infection, even bacteria that are very mild without causing any disease can enter your body producing various symptoms. The vital molecule glutathione is present in all cells including the cells of the immune system. They readily ward off any kind of infection. You have to keep the optimum level of glutathione inside the cells. All you really have to do is keep a diet rich in glutathione and help your body to create more of it.

Glutathione and detoxification

There is a wonderful organ in our body - the liver. It synthesizes protein, stores energy and removes the toxic substances from the body. Whatever is considered a foreign substance and deemed toxic, are removed from the body by the liver. With the help of a few chemical substances and a few chemical reactions involving them, the liver neutralizes these toxic substances by a process called detoxification.

Detoxification occurs in two phases - phase I and phase II reactions. A number of chemical substances are involved in this. And the most important one is the glutathione. Though glutathione is available in many natural food substances like fresh fruits and vegetables, the liver can synthesize glutathione on its own when necessity arises.

Glutathione and cancer

With improved standard of living and better medical facilities, the diseases caused by infections have decreased. But there is an increase in the incidence of many non-infectious diseases including cancer. Research has shown that people who suffer from cancer have low levels of glutathione in their body. By keeping the glutathione at normal levels, cancer can either be prevented or its progression can be stopped.

To order your natural health supplement (with a composition patent) go to www.gojo.max4u.com

2009-12-01T12:20:00.001-08:00

Glutathione (GSH) is an important endogenous antioxidant found in millimolar concentrations in the brain. GSH levels have been shown to decrease with aging. Alzheimer's disease (AD) is a neurodegenerative disorder associated with aging and oxidative stress. Aß (1- 42) has been shown to induce oxidative stress and has been proposed to play a central role in the oxidative damage detected in AD brain. It has been shown that administration of Gamma-glutamylcysteine ethyl ester (GCEE) increases cellular levels of GSH, circumventing the regulation of GSH biosynthesis by providing the limiting substrate. In this study, we evaluated the protective role of up-regulation of GSH by GCEE against the oxidative and neurotoxic effects of Aß(1- 42) in primary neuronal culture. Addition of GCEE to neurons led to an elevated mean cellular GSH level compared with untreated control. Inhibition of ?-glutamylcysteine synthetase by buthionine sulfoximine (BSO) led to a 98% decrease in total cellular GSH compared with control, which was returned to control levels by addition of GCEE. Taken together, these results suggest that GCEE up-regulates cellular GSH levels which, in turn, protects neurons against protein oxidation, loss of mitochondrial function, and DNA fragmentation induced by Aß(1- 42). These results are consistent with the notion that up-regulation of GSH by GCEE may play a viable protective role in the oxidative and neurotoxicity induced by Aß(1- 42) in AD brain.

2009-11-26T16:03:00.000-08:00

What is glutathione?
It is a small protein produced naturally in our cells when certain required elements are present. It functions both as an antioxidant and an antitoxin and is a major defense system against illness and aging. Our glutathione level actually indicates our state of health and can predict longevity. There are more than 60,000 published papers on the beneficial effects of glutathione. In the near future the importance of glutathione will be widely recognized because it has the ability to boost the immune system and fight off the damage of free radicals on the cells. Various daily activities can reduce your glutathione such as stress, exercise, infection, injury and environmental toxins. Your glutathione, or in other words, your body's natural defense against aging and cellular damage decreases by about 10% to 15% every decade!*

Modern research has shown that individuals who have low levels of glutathione are susceptible to chronic illness.Decreased levels of glutathione can be brought about by continual stress upon the immune system. As we now know, a lowered immune system can bring about illness and disease. This is a ferocious cycle. While you need glutathione for a productive immune system, a weakened immune system hampers the production of glutathione.*

Increasing age and other factors reduce the body's production and utilization of glutathione

Beginning around the age of 20 your body's natural production of this powerful little protein declines about 10 to 15 percent every decade. It is well understood in the medical and scientific community that intracellular glutathione levels cannot effectively be raised by oral glutathione supplementation because it is believed to be destroyed in the digestive system; which is why MaxGXL® is such a groundbreaking discovery.*

To reiterate:*

Glutathione slows down the aging process
Glutathione detoxifies and improves liver function
Glutathione strengthens the immune system
Glutathione works to help improve mental functions
Increases energy
Improves concentration
Permits increased exercise
Glutathione improves heart and lung function...just to name a few