Alzforum - Papers of the Week: 17-23 Jul 2026

Glycopolymers as emerging modulators of Amyloid-β aggregation: structure-activity relationships and therapeutic potential.

Carbohydr Polym. 2026 Sep 15;388:125572. Epub 2026 Jun 21
Authors: Cardoso E, Serra AC, Coelho JF, Pereira P
PubMed: 42493137
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Corrigendum to "Heparan sulfate from porcine mucosa promotes amyloid-beta clearance in APP/PS1 mice and alleviates Alzheimer's pathology" [Carbohydrate Polymers 285 (2022) 119205].

Carbohydr Polym. 2026 Sep 15;388:125541. Epub 2026 Jun 11
Authors: Wu L, Jiang W, Zhao N, Wang F
PubMed: 42493106
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Efficacy Measures Used in Alzheimer Disease Clinical Trials Between 2015 and 2025: A Systematic Review.

Neurology. 2026 Aug 25;107(4):e218373. Epub 2026 Jul 23
Authors: Li C, Fu M, Berg K, Wallach J, Ling K, Wei R, Shi L, Ross J, Guan X
PubMed: 42492033
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Clinical Trial Outcomes in the Alzheimer's Disease Spectrum: What Should We Measure?

Neurology. 2026 Aug 25;107(4):e218468. Epub 2026 Jul 23
Authors: Turner RS
PubMed: 42492030
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Microglia heterogeneity in vascular dementia pathology.

iScience. 2026 Aug 21;29(8):116222. Epub 2026 Jul 9
Authors: Tan Z, Xu D, Cao Y, Li W, Ma J, Li H, Wei W
PubMed: 42473665
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The Promise and Peril of Alzheimer Disease Prevention.

Neurology. 2026 Aug 11;107(3):e218348. Epub 2026 Jul 17
Authors: Grill JD, Graff-Radford J
PubMed: 42467872
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Rapidly Progressive Alzheimer Disease and Related Dementias as a Phase Transition: Symptom Cascades and Survival Inflection.

Neurology. 2026 Aug 11;107(3):e218350. Epub 2026 Jul 20
Authors: Tang C, Yang J, Luo W, Lei X, Peng X, Chen Y, Guan S, He D
PubMed: 42475650
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Association Between Plasma GFAP and Medial Temporal Atrophy and Cognition in Amyloid-Negative Cerebrovascular Disease.

Neurology. 2026 Aug 11;107(3):e218336. Epub 2026 Jul 21
Authors: Oliveira-Junior MS, Rodrigues MS, Amaral L, Povala G, Rocha A, Scop Medeiros M, Abbas S, Ferrari-Souza JP, Saha P, Lussier FZ, Ferreira PC, Bauer-Negrini G, Soares C, Roh HW, Zimmer ER, Karikari T, Karim H, Rosa-Neto P, Hong CH, Tudorascu D, Son SJ, Bellaver B, Pascoal T
PubMed: 42479994
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Association Between Postmortem Pathologic Burden and the Rate of Clinical Progression in Patients With Frontotemporal Lobar Degeneration.

Neurology. 2026 Aug 11;107(3):e218278. Epub 2026 Jul 21
Authors: Magee RG, Xie SX, Ohm DT, Rhodes E, Massimo L, Van Deerlin VM, Wolk DA, Lee EB, Mcmillan CT, Irwin DJ
PubMed: 42479989
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Associations of Alzheimer Disease and Related Dementia Neuropathologies With Timely Diagnosis of Dementia in Healthcare Settings.

Neurology. 2026 Aug 11;107(3):e218352. Epub 2026 Jul 22
Authors: Chen Y, Chen A, Power MC, Grodstein F, Kapasi A, Capuano AW, Lange-Maia BS, Moghtaderi A, Stapp EK, Bhattacharyya J, Shah RC, Barnes LL, Bennett DA, James BD
PubMed: 42485607
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How Good Are Clinicians at Diagnosing Different Dementia-Related Neuropathologies?

Neurology. 2026 Aug 11;107(3):e218463. Epub 2026 Jul 22
Authors: Ebmeier KP
PubMed: 42485606
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Engineering selective amyloid precursor protein inhibitors by machine learning and deep mutational scanning.

Protein Sci. 2026 Aug;35(8):e70712.
Authors: Meiri R, Reuveni O, Levi M, Radisky ES, Papo N, Orenstein Y
PubMed: 42477885
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The Effectiveness of Animal-Assisted Interventions for People Living With Dementia: An Overview of Systematic Reviews and Meta-Analysis.

Int J Nurs Pract. 2026 Aug;32(4):e70172.
Authors: Zhou J, Li S, Liu H, Sun Y, Wang Z
PubMed: 42487544
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Antidepressant is approved to treat agitation in Alzheimer disease.

Am J Nurs. 2026 Aug 1;126(8):18-19. Epub 2026 Jul 23
Authors: Aschenbrenner DS
PubMed: 42487190
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The dual face of miR-146a in ALS.

Proc Natl Acad Sci U S A. 2026 Jul 28;123(30):e2617170123. Epub 2026 Jul 20
Authors: Haim G, Hornstein E
PubMed: 42475592
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Deciphering the mechanism of protein aggregation and effects of inhibitors using single-molecule mass photometry.

Proc Natl Acad Sci U S A. 2026 Jul 28;123(30):e2536600123. Epub 2026 Jul 22
Authors: Lyons A, Paul SS, MacArthur JE, Hoffman GN, Yarahmady A, Mok SA, Woodside MT
PubMed: 42485386
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[Research progress on acupuncture-moxibustion regulating brain energy metabolism to intervene in Alzheimer's disease].

Zhen Ci Yan Jiu. 2026 Jul 25;51(7):923-932.
Authors: Li L, Hong C, Xie WT, Zhang RZ, Wei YT, Ma C, Yan XK
PubMed: 42482587
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[Effects of electroacupuncture on motor function and PGC-1α/FNDC5/BDNF pathway in muscle and brain of SAMP8 mice].

Zhen Ci Yan Jiu. 2026 Jul 25;51(7):887-895.
Authors: Yang SM, Guo WQ, Dong WG, Huang JY, Huang ST, Huang Y, Zhan SJ, Lin L, Wang F, Liu LL
PubMed: 42482583
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Norepinephrine-mediated regulation of endogenous Aβ42 peptide levels: effects of noradrenergic depletion and restoration.

MedScience. 2026 Jul 24; Epub 2026 Jul 24
Authors: Hoffman I, Ross JA, Tumasz M, Thomas SA, Van Bockstaele EJ
PubMed: 42493706
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SuperAging is not the inverse of common-variant Alzheimer's risk: evidence across genetic ancestries.

Alzheimers Res Ther. 2026 Jul 23;18(1)
Authors: Piras IS, Capuano AW, Maher AC, Schafer R, Bonfitto A, Song S, Taguinod F, Goldstein F, Roberts A, Okonkwo O, Martersteck A, SuperAging Research Initiative, Huentelman MJ, Rogalski E
PubMed: 42493810
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Application of the Allen Human Brain Atlas in Alzheimer's disease and Parkinson's disease.

Transl Neurodegener. 2026 Jul 23;15(1)
Authors: Xiao Y, Wang S, Hou Y, Shang H
PubMed: 42493790
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Crowdsourcing and machine learning contests in Parkinson's disease research - when do they work?

J Parkinsons Dis. 2026 Jul 23;:1877718X261452116. Epub 2026 Jul 23
Authors: Kirsch LC, Hausdorff JM, Dardov VJ
PubMed: 42493769
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Early detection of Alzheimer's disease with circular RNA from blood.

Nat Med. 2026 Jul 23; Epub 2026 Jul 23
Authors:
PubMed: 42493572
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In silico pipeline for GSK 3β inhibitor discovery in Alzheimer's disease using pharmacophore screening, docking, ADME filtering, and MD validation.

Sci Rep. 2026 Jul 23;16(1)
Authors: Elkotamy MS, Elgohary MK, Alkotami AS, Eldesouki MM, Elsayed ZM, Mattar AA, Abo-Ashour MF, Tawfik HO, Eldehna WM, Abdel-Aziz HA
PubMed: 42493523
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Integrated identification and validation of HSP90AA1 as a therapeutic target of Astragalus membranaceus in Alzheimer's disease.

Neuroscience. 2026 Jul 23; Epub 2026 Jul 23
Authors: Xie M, Niu X, Shi L
PubMed: 42492887
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The mechanism by which long-term exposure to TDCIPP promotes cognitive impairment in 3×Tg-AD mice: insights from multi-omics studies.

Neurotoxicology. 2026 Jul 23;:103530. Epub 2026 Jul 23
Authors: Yang T, Liu Y, Liang R, Wen C, Yan J, Chen X, Liu P, Yang X, Xu B, Liu J
PubMed: 42492782
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Subchronic Benzo[a]pyrene Exposure Disrupts APOE4-Regulated Lipid Metabolism to Induce Tau Hyperphosphorylation and Cognitive Deficits.

Neurotoxicology. 2026 Jul 23;:103532. Epub 2026 Jul 23
Authors: Wang W, Zhu X, Geng S, Wang Y, Zhang W, Zhang W, Gao X, Mo Y, Zhang Q, Nie J
PubMed: 42492781
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Retraction notice to "Role of miRNA regulation in IGFBP-2 overexpression and neuronal ferroptosis: Insights into the Nrf2/SLC7A11/GPX4 pathway in Alzheimer's disease" [International Journal of Biological Macromolecules 287 (2025) 138537].

Int J Biol Macromol. 2026 Jul 23;:153649. Epub 2026 Jul 23
Authors: Luo C, Wu G, Xiao Z, Hu R, Qiao M, Li W, Liu C, Li Z, Lan C, Huang Z
PubMed: 42492708
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A systematic review and meta-analysis of visuospatial attentional deficits in Parkinson's patients.

Neurosci Biobehav Rev. 2026 Jul 23;:106884. Epub 2026 Jul 23
Authors: Bucur M, Holcomb AN, Luciani M, Papagno C, Schintu S
PubMed: 42492675
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A scalable touchscreen-based spatial working memory task for cross-species research.

Neurobiol Learn Mem. 2026 Jul 23;:108200. Epub 2026 Jul 23
Authors: Vanderlip CR, Dunn SR, Asch PA, Stark CE, Glavis-Boom C
PubMed: 42492654
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A promising therapeutic strategy reduces abnormal Aβ deposition and inhibits neuronal apoptosis via FGF17 ameliorating AD-like neurodegeneration.

Brain Res. 2026 Jul 23;1889:150474. Epub 2026 Jul 23
Authors: Wang Y, Qin S, Gong X, Bai H, Li S, Cai H, Hu Y, Zhao Y, Bai M, Song C, Liu W, Kong X, Yue W
PubMed: 42492602
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[Predicting and Preventing Alzheimer's Disease].

Fortschr Neurol Psychiatr. 2026 Jul 23; Epub 2026 Jul 23
Authors: Weber MC, Goedecke J, Fink GR, Onur OA
PubMed: 42492536
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Chronic lead exposure disrupts copper redox homeostasis and aggravates neurodegeneration.

Environ Pollut. 2026 Jul 23;407:128818. Epub 2026 Jul 23
Authors: Hu J, Wang WX
PubMed: 42492469
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Site-targeted proximal complement C3 inhibition, but not C5 blockade, attenuates neurodegeneration in a mouse model of amyotrophic lateral sclerosis: Implications for failed clinical trials.

Neurotherapeutics. 2026 Jul 23;23(5):e00969. Epub 2026 Jul 23
Authors: Majumder M, Borucki DM, Chowdhury N, Mallah K, Tomlinson S
PubMed: 42492371
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Natural polysaccharides as multi-target therapeutic candidates for Alzheimer's disease: Mechanisms, structure-activity relationships, and translational perspectives.

Phytomedicine. 2026 Jul 23;159:158585. Epub 2026 Jul 23
Authors: Luo S, Guo J, Xu J, Song J, Dai Y, Xu S
PubMed: 42492268
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Single-cell multiomics connects 3D genome and transcriptome alterations in Alzheimer's disease.

Science. 2026 Jul 23;393(6809):eadz1652. Epub 2026 Jul 23
Authors: Zhang Y, Lu X, Kunisky AK, Alam S, Tang J, Zhang R, Wang S, Zhang H, Baroudi J, Ichcho W, Jia D, Ghorbanikalateh S, Ghorbanikalateh S, Wang S, Bennett DA, Mathys H, Duan Z, Ma J
PubMed: 42490473
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Alzheimer's trial results lend momentum to drugs targeting tau.

Science. 2026 Jul 23;393(6809):343-344. Epub 2026 Jul 23
Authors: Smith JE
PubMed: 42490471
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On the Directionality of Predictor-Outcome Assignment When Modeling Polygenic Risk for Alzheimer's Disease Alongside Sleep Arousal Phenotypes.

Sleep. 2026 Jul 23; Epub 2026 Jul 23
Authors: Lu X, Shen X
PubMed: 42490402
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Emerging Trends from the 30 Most Cited Papers on Iatrogenic Cerebral Amyloid Angiopathy: A Bibliometric Review.

Eur Neurol. 2026 Jul 23;:1-18. Epub 2026 Jul 23
Authors: Alderete JA, Clarke JE, Ratnaparkhi A, Rajakumar S, Alvarado A, Harper SD, Acharya J
PubMed: 42490344
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Ethical Considerations of Artificial Intelligence in Dementia Research: A Review of Reviews.

Gerontologist. 2026 Jul 23; Epub 2026 Jul 23
Authors: Ko E, Cho H
PubMed: 42490197
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Considerations in Alzheimer's Disease in Women.

Curr Neurol Neurosci Rep. 2026 Jul 23;26(1)
Authors: Just C, Seibert K, Chan C, Maldonado-Correa C, Jones D
PubMed: 42490036
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Elevated CSF GAP-43 is associated with reduced cerebral glucose metabolism and cognitive impairment in individuals with mild cognitive impairment.

Brain Imaging Behav. 2026 Jul 23;20(4)
Authors: Ahmed HM, Al-Hussainy AF, Arora V, Rekha MM, Kundlas M, Chennakesavulu K, Manu M, Rizaev J, Taher SG, Alwan M, Jawad M, Mushtaq H
PubMed: 42489996
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Interstitial fluid rejuvenation through young-donor plasma exchange in cognitively impaired patients: a pilot safety and feasibility study.

Geroscience. 2026 Jul 23; Epub 2026 Jul 23
Authors: Søraas A, Engvig A, Alnæs D, Karim LN, Danilova E, Istre MS, Nygaard S, Utgård TR, Ceprnjic S, Reiakvam O, Edvardsen E, Westlye LT, Nygaard AB, Dahl JA, Nissen-Meyer LS, Ihle-Hansen H, Holland P
PubMed: 42489967
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From synaptic development to degeneration: a narrative review of small molecule strategies targeting alpha-synuclein in Parkinson's disease.

Metab Brain Dis. 2026 Jul 23;41(1)
Authors: Khoo L, Ng KY, Chye CL, Ko Y, Lee JY, Koh Y, Tsen MT, Chye SM
PubMed: 42489942
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Chronic schizophrenia versus Alzheimer's disease: neuroimaging perspectives on the late-life course of schizophrenia.

J Neural Transm (Vienna). 2026 Jul 23; Epub 2026 Jul 23
Authors: Noroozian M, Givian H, Vafaee MS
PubMed: 42489907
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Psychiatric disorders in amyotrophic lateral sclerosis: a short note.

J Neural Transm (Vienna). 2026 Jul 23; Epub 2026 Jul 23
Authors: Jellinger KA
PubMed: 42489904
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Correction: Trace Elements Dyshomeostasis and Toxic Metals Neurotoxicity in Neurodegenerative Diseases.

Biol Trace Elem Res. 2026 Jul 23; Epub 2026 Jul 23
Authors: Tang M, Fleming E, Gu J, Shi H, Xu Y, Gong X
PubMed: 42489795
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Do anti-amyloid therapies demonstrate clinically meaningful benefit? A Bayesian reappraisal.

J Alzheimers Dis. 2026 Jul 23;:13872877261469870. Epub 2026 Jul 23
Authors: Costa T, Sensi SL, Høilund-Carlsen PF, Robakis NK, Vissel B, Espay AJ
PubMed: 42489536
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MRI-free amyloid PET quantification using a deep learning model and white matter reference.

J Alzheimers Dis. 2026 Jul 23;:13872877261470021. Epub 2026 Jul 23
Authors: Shin SH, Mo Y, Hwang HS, Lee M, Lee JJ, Kim C, Choi HJ
PubMed: 42489532
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Biochemical modulators of synaptic plasticity: New horizons in Alzheimer's disease treatment.

J Alzheimers Dis. 2026 Jul 23;:13872877261469864. Epub 2026 Jul 23
Authors: Farzeen I, Nazir MM, Jaan Z, Ghaffar W, Masood A, Yasmeen M, Ashraf A, Różański H
PubMed: 42489531
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Elevated ferritin expression in microglia and extracellular amyloid-β deposition are associated with reduced neurofibrillary degeneration in human isocortex, but not allocortex.

J Alzheimers Dis. 2026 Jul 23;:13872877261470454. Epub 2026 Jul 23
Authors: Streit WJ, Kuhrt H, Bechmann I
PubMed: 42489527
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Reduced differentiation of personality in Alzheimer's disease-like dementia and associations between informant report of personality change and cognitive decline.

J Alzheimers Dis. 2026 Jul 23;:13872877261469839. Epub 2026 Jul 23
Authors: Gobbo S, Romano D
PubMed: 42489523
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Better cardiovascular health, measured by Life's Simple 7, is associated with lower white matter hyperintensity burden and greater cerebral blood flow over time.

J Alzheimers Dis. 2026 Jul 23;:13872877261467045. Epub 2026 Jul 23
Authors: Denier-Fields DN, Gangnon RE, Rivera-Rivera LA, Betthauser TJ, Bendlin BB, Johnson SC, Engelman CD
PubMed: 42489522
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Precuneus amyloid-β deposition involving the association of irritability and cognitive decline: A multi-cohort longitudinal study.

J Alzheimers Dis. 2026 Jul 23;:13872877261467432. Epub 2026 Jul 23
Authors: Liu Y, Qiu Q, Yue L, Hong B, Su N, Li W, Xiao S, Sun L, Chen J, Alzheimer’s Disease Neuroimaging Initiative (ADNI)
PubMed: 42489457
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Episodic memory and associated cortical atrophy in amnestic early-onset and late-onset Alzheimer's disease.

J Alzheimers Dis. 2026 Jul 23;:13872877261469183. Epub 2026 Jul 23
Authors: Keith CM, Haut MW, Worhunsky P, Vieira Ligo Teixeira C, Mehta RI, Malone J, Phelps H, Ward M, Miller M, Pockl S, Rajabalee N, Marano G, McCuddy WT, D'Haese PF, Rezai A
PubMed: 42489442
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Early cerebral amyloid angiopathy-related pathology is associated with localized functional brain connectivity.

J Alzheimers Dis. 2026 Jul 23;:13872877261469189. Epub 2026 Jul 23
Authors: Drenth N, van Dijk SE, Hafkemeijer A, Rombouts SA, van der Grond J, van Rooden S
PubMed: 42489441
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APOE4-specific glymphatic effects on clinical progression in the Alzheimer's Disease Neuroimaging Initiative with pathological correlates in the A4 study.

J Alzheimers Dis. 2026 Jul 23;:13872877261469565. Epub 2026 Jul 23
Authors: Saadawy M, Majeed M, Saadawy E, Alzheimer's Disease Neuroimaging Initiative *
PubMed: 42489438
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Recruitment challenges and strategies for engaging the Peruvian population in the ReDLat Study.

J Alzheimers Dis. 2026 Jul 23;:13872877261467782. Epub 2026 Jul 23
Authors: Custodio B, Montesinos R, Agüero K, Huilca JC, Verastegui G, Bartolo P, Nuñez-Huanca M, Albujar Pereira MF, Godoy ME, Ibáñez A, Custodio N
PubMed: 42489432
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Down syndrome-associated trisomic chromosomal regions modify amyloid-β accumulation and cause early death in a mouse model of aspects of Alzheimer's disease.

J Alzheimers Dis. 2026 Jul 23;:13872877261469121. Epub 2026 Jul 23
Authors: Ishihara K, Yasui H, Harada K, Amano K, Saito M, Kaneda K, Katsuda M, Kawashita E, Hata T, Annoura R, Nishimura K, Terasaki R, Sago H, Shimohama S, Akiba S, Yamakawa K, Takata K
PubMed: 42489430
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Latent variables in cognitive decline: introducing a behavioral-relational factor.

J Clin Exp Neuropsychol. 2026 Jul 23;:1-10. Epub 2026 Jul 23
Authors: Chrzanowski L, Peeples LB, Mast BT, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42489366
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A Blood-Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN-Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1.

Adv Sci (Weinh). 2026 Jul 23;:e76778. Epub 2026 Jul 23
Authors: Xie Q, Zhu Y, Jiang W, Xie H, Li Y, Hu M, Li K, Yu H, Pan Y, Jiang C, Song X, Fan D, Deng B
PubMed: 42489267
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Simulations of an Extended Tau/Tubulins Interface Reveal a Complex Disorder-Disorder Interplay Mediated by the C-Terminal Tails.

J Phys Chem B. 2026 Jul 23; Epub 2026 Jul 23
Authors: Marien J, Prévost C, Sacquin-Mora S
PubMed: 42489236
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Photobiomodulation of immune crosstalk rescues neuroinflammation in Alzheimer's disease models.

Brain. 2026 Jul 23; Epub 2026 Jul 23
Authors: Shen Q, Chang H, Li J, Guo H, Shi W, Yan Y, Ouyang W, Zhang Z, Wu X, Xing D, Yang S
PubMed: 42489128
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Functional analysis of late-onset Alzheimer's disease risk genes in Caenorhabditis elegans identifies regulators of neuronal aging.

Transl Neurodegener. 2026 Jul 23;15(1)
Authors: Waghmare SG, Krishna MM, Maccoux EC, Franitza AL, Link BA, E L
PubMed: 42487135
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Comparative efficacy and safety of photobiomodulation, transcranial direct current stimulation, and repetitive transcranial magnetic stimulation in Alzheimer's disease: a network meta-analysis of randomized controlled trials.

Lasers Med Sci. 2026 Jul 23;41(1)
Authors: Xu W, Chen J, Zhou Y, Liu C, Han Y, Zheng K
PubMed: 42487022
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Adaptive pathways for multimodal community-based detection of cognitive impairment: the CogScreen I study.

Sci Rep. 2026 Jul 23;16(1)
Authors: Kurz C, Wüsten NC, Tegethoff P, Taute M, Kehrls M, Hufnagel A, de Jonge S, Deckert A, Suchsland MZ, König A, Feustel E, Heindl P, Mattke S, Perneczky R
PubMed: 42486877
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Chronic Pain and the Risk of Dementia: A Systematic Review and Meta-Analysis.

Curr Pain Headache Rep. 2026 Jul 22;30(1)
Authors: Lin Q, Qiu N, Wang X, Wei YB, Liu JJ
PubMed: 42484959
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The Clearance-Centered Bottleneck in Alzheimer's Disease: From Coupled Glymphatic-Lymphatic Circuits to Therapeutic Opportunities.

Mol Neurobiol. 2026 Jul 22;63(1)
Authors: Wu P, Liao Y, Liu C, Liu X, Feng Q, Cheng X
PubMed: 42484938
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The PERK paradox in aging: how ER stress shapes senescence and neurodegeneration.

Geroscience. 2026 Jul 22; Epub 2026 Jul 22
Authors: Pandey V, Sachdeva R, Despa S
PubMed: 42484801
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EPIC4ND-European Prospective Investigation into Cancer and Nutrition follow-up for neurodegenerative diseases.

Eur J Epidemiol. 2026 Jul 22; Epub 2026 Jul 22
Authors: Lill CM, Homann J, Ohlei O, Smith-Byrne K, Viallon V, Huerta JM, Artaud F, Zhao Y, Britten A, Deecke L, Dobricic V, Mokoroa O, Guevara M, Petrova D, Trupp M, Sabin J, Gröninger M, Colorado-Yohar SM, Alonso-Martin S, Cabrera-Castro N, Groppa S, Robinson O, Hansen J, Eriksson S, Sieri S, Jimenez A, Tong TY, Kaaks R, Severi G, Travis R, Wareham N, Benedet AL, Zetterberg H, Franke A, Elbaz A, Bertram L, Vermeulen R, Middleton L, Masala G, Sacerdote C, Peters S, Katzke V, Ferrari P, Gunter MJ, Riboli E
PubMed: 42484778
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Serial failure of the brain clearance continuum in Alzheimer's disease: mechanisms and therapeutic perspectives.

J Neurol. 2026 Jul 22;273(8)
Authors: Yao Q, Han X, Cui T, Li D, Shan A, Wang X, Li S, Luan H, Zhu Y, Wen B, Sun Y, Li C, Sun Q, Wei C
PubMed: 42484690
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When neurodegenerative disease masquerades as psychiatric illness: A clinical case study of early-onset frontotemporal dementia.

Appl Neuropsychol Adult. 2026 Jul 22;:1-6. Epub 2026 Jul 22
Authors: Heywood A, Robinson AD, Maniar N, Zhu F, Soble JR, Phillips MS
PubMed: 42484561
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Quantitative correlation between extracellular matrix protein degradation and the progression of neurodegeneration in Alzheimer's disease.

J Alzheimers Dis. 2026 Jul 22;:13872877261470815. Epub 2026 Jul 22
Authors: Ashar MS, Anwar M, Singh AK, Pradhan R, Gupta A, Chakrawarty A, Haldar P, Tripathi M, Dey S
PubMed: 42484559
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E326K GBA polymorphism is associated with clinical and pathological features of synucleinopathy in the absence of overt Parkinson's disease or Lewy body dementia.

J Parkinsons Dis. 2026 Jul 22;:1877718X261468542. Epub 2026 Jul 22
Authors: Arnold MR, Westaway SK, Woltjer RL, Gray NE, Quinn JF
PubMed: 42484558
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Retinal structural and microvascular alterations as biomarkers of cerebral pathology and cognitive decline in Alzheimer's disease: An OCT/OCTA study.

J Alzheimers Dis. 2026 Jul 22;:13872877261470439. Epub 2026 Jul 22
Authors: Chen Y, Kwapong WR, Chen X, Gao Y, Chu M, Zhang X, Wu L
PubMed: 42484463
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SOD1-lowering therapy for patients with wildtype SOD1-ALS: a case report.

Amyotroph Lateral Scler Frontotemporal Degener. 2026 Jul 22;:1-3. Epub 2026 Jul 22
Authors: Carberry N, Wuu J, Benatar M
PubMed: 42484074
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Mathematical mapping of circadian genes in Alzheimer's disease.

Chronobiol Int. 2026 Jul 22;:1-15. Epub 2026 Jul 22
Authors: S V, K V, Raja R, A R
PubMed: 42483877
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Efficacy and Safety of Mesenchymal Stem Cell Therapy for Alzheimer's Disease: A Systematic Review and Meta-Analysis.

Stem Cells Dev. 2026 Jul 22;:15473287261468404. Epub 2026 Jul 22
Authors: Wen Y, Zhan S, Duan Y, Pang M, Yan J, Deng M, Fan H
PubMed: 42483783
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Differential effects of hormone therapy formulations on Parkinson's disease risk: a systematic review and meta-analysis.

Neurol Sci. 2026 Jul 22;47(8)
Authors: Macedo VF, de Melo Barboza AM
PubMed: 42481816
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Early-life sugar rationing, brain aging, and long-term neurodegenerative and psychiatric health outcomes: a population-based natural experiment study.

NPJ Aging. 2026 Jul 22; Epub 2026 Jul 22
Authors: Lian X, Chen A, Zhu X, Huang Y, Yang C, Huang Y, Ran M, Yin L, Zhang B
PubMed: 42481525
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Retraction notice to "Molecular mechanisms of MAPK9, BAX, and TFEB proteins: Genetic correlations between oxidative stress and autophagy pathways in Alzheimer's disease" [Int. J. Biol. Macromol. 309 (2025) 143196].

Int J Biol Macromol. 2026 Jul 22;:153568. Epub 2026 Jul 22
Authors: Huang X, Wang J, Zhao X, Sooranna SR, Liao B, Jian C, Shang J, Li X
PubMed: 42481337
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Attitudes in Patients With Prodromal and Overt α-Synucleinopathy Toward Risk Disclosure: A Nationwide Registry.

Mov Disord Clin Pract. 2026 Jul 22; Epub 2026 Jul 22
Authors: Yilmaz R, Çakan GC, Karadağ YS, Hoş ÜD, Acarer A, Kabeloğlu V, Sonkaya R, Genç G, Gunduz A, Koçer B, Yılmaz H, Erer S, Gultekin M, Tokçaer AB, Ataoğlu EE, Samanci B, Gençler OS, Tuncel R, Şahin E, Pak T, Demirelli DS, İbiş SY, Çöklü H, Baydemir R, Altun RU, Güllü G, Çiftçi ÖF, Metin KM, Demiryürek BE, Çakmaklı GY, Bilgiç B, Dogu O, Özer F, Aksu M, Berktas DT, Akyildiz UO, Karadeniz D, Çokal BG, Demir AB, Gençdal IY, Saritas AS, Ak AK, Şahin A, Aslan-Kara K, Ismailogullari S, Tezer FI, Hanağası H, Akbostancı MC, St Louis EK, Şenel GB
PubMed: 42487477
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Relation of fluid neurodegeneration biomarkers with white matter integrity in Alzheimer's disease patients in Latin America.

J Alzheimers Dis. 2026 Jul 22;:13872877261467065. Epub 2026 Jul 22
Authors: Magalhães TN, Casseb RF, Moraes AS, Teixeira CV, Carletti AM, De Rezende TJ, Joaquim HP, Talib LL, Forlenza O, Cendes F, Balthazar ML, Teunissen CE
PubMed: 42487153
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Early Detection of Cognitive Impairment Using Time-Frequency Analysis of Fine Motor Accelerometry.

Ann Biomed Eng. 2026 Jul 22; Epub 2026 Jul 22
Authors: Pacheco-Santiago G, González-Aparicio II, Domínguez-Vega ZT, Velázquez-Álvarez L, Torres-Castillo JR, Rivera-Sánchez JJ, Padilla-Castañeda MÁ
PubMed: 42487042
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TMBIM6: at the intersection between proteostasis dysregulation and Parkinson's disease.

Cell Death Differ. 2026 Jul 22; Epub 2026 Jul 22
Authors: Hetz C, Bailly-Maitre B
PubMed: 42486950
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A multimodal machine learning model integrating plasma biomarkers and MRI metrics for non-invasive prediction of amyloid-β pathology in mild cognitive impairment.

J Alzheimers Dis. 2026 Jul 22;:13872877261465672. Epub 2026 Jul 22
Authors: Fang Q, Guo Y, Chen L, Li Y, Cai Q, Zhang J, Ma X, Zeng Y, Bai G
PubMed: 42486687
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Cross-sectional analysis of variation in diagnosis of Lewy body dementia in three English regions: data from the DETERMIND programme.

BMJ Open. 2026 Jul 22;16(7):e121991.
Authors: Hamilton CA, Thomas AJ, Donaghy PC, Hicks B, Mueller C, Banerjee S
PubMed: 42486521
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A comparative evaluation of multiple enlarged perivascular space segmentation tools.

Magn Reson Imaging. 2026 Jul 22;134:110749. Epub 2026 Jul 22
Authors: LeFevre JD, Robb WH, Liu D, Jackson TB, Pechman KR, Shashikumar N, Vyas Y, Landman BA, Davis LT, Hohman TJ, Jefferson AL
PubMed: 42486379
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Metformin enhances hippocampal excitatory synaptic transmission and preserves synaptic plasticity under amyloid-β oligomer-induced dysfunction.

Neuropharmacology. 2026 Jul 22;299:111116. Epub 2026 Jul 22
Authors: Arriagada J, Ardiles Á, Mery E, Garay C, Conejera F, Herrera EA, Paula-Lima A, Muñoz P
PubMed: 42486330
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Repressor Element 1 Silencing Transcription Factor as a central regulator of autophagy and neuroinflammation in Alzheimer's disease.

Eur J Pharmacol. 2026 Jul 22;:179168. Epub 2026 Jul 22
Authors: Dilip PI, Daksh R, Sharma P, Khanna S, Bojja SL, Singh AK, Nampoothiri M
PubMed: 42486320
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Spatial Transcriptomic Decoupling and Magnetic Resonance Imaging Identify the Genetic and Cytoarchitectonic Correlates of Regional Vulnerability in Alzheimer's Disease.

Neuroimage. 2026 Jul 22;:122144. Epub 2026 Jul 22
Authors: Jafar T, Chowdhury NF, Irimia A
PubMed: 42486312
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Correction for Stöhr et al., Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice.

Proc Natl Acad Sci U S A. 2026 Jul 21;123(29):e2622455123. Epub 2026 Jul 17
Authors:
PubMed: 42467516
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Amygdalar nuclei vulnerability to protein aggregates in Lewy body diseases.

Acta Neuropathol Commun. 2026 Jul 21; Epub 2026 Jul 21
Authors: Deshayes NA, van Wetering J, Wesseling A, Vos F, Ingrassia A, Galis Y, Jonkman LE, Rozemuller AJ, van de Berg WD
PubMed: 42477717
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Creutzfeldt-Jakob disease surveillance in Australia: update to 31 December 2025.

Commun Dis Intell (2018). 2026 Jul 21;50
Authors: Stehmann C, Senesi M, Sarros S, McGlade A, Lewis V, Klug G, Holper S, McLean C, Masters C, Collins S
PubMed: 42475727
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Neurotransmitter-Defined Degeneration Patterns in Sporadic and C9orf72-Associated Amyotrophic Lateral Sclerosis: Predilection to GABAergic, Serotonergic, Opioid, Glutamatergic, Endocannabinoid, and Microglial Systems-Implications for Therapy Development.

Ann Neurol. 2026 Jul 21; Epub 2026 Jul 21
Authors: Tahedl M, Siah WF, Lope J, Hengeveld JC, Doherty MA, McLaughlin RL, Hardiman O, Tan EL, Toomey A, Kleinerova J, Bede P
PubMed: 42479906
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Heterojunction-Mediated Dual-Site Synergistic Catalysis for Enhanced Electrochemiluminescence Detection of α-Synuclein.

Anal Chem. 2026 Jul 21; Epub 2026 Jul 21
Authors: Li Y, Dong X, Wu T, Ren X, Du Y, Ju H, Wei Q
PubMed: 42479881
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Are MMSE and ACE-R useful for detecting the earliest stages of Alzheimer's disease? A comparative study.

J Neuropsychol. 2026 Jul 21; Epub 2026 Jul 21
Authors: Bonarota S, Caruso G, Di Domenico C, Di Lorenzo F, Koch G, Caltagirone C, Bozzali M, Serra L
PubMed: 42479744
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[Focus on limbic-predominant age-related TDP-43 encephalopathy (LATE)].

Geriatr Psychol Neuropsychiatr Vieil. 2026 Jul 21;24(3) Epub 2026 Jul 21
Authors: Buard G, Verny M
PubMed: 42479714
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Integrated bioinformatics and experimental analysis identify apoptosis- and pyroptosis-related hub genes as candidate diagnostic biomarkers in Alzheimer's disease.

J Appl Genet. 2026 Jul 21; Epub 2026 Jul 21
Authors: Cai Y, Chen Y, Huang G, Ren M, Chai Y, Gai C, Huang X, Yan T
PubMed: 42479414
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Seipin modulates Alzheimer's disease pathogenesis by regulating ferroptosis through a glycine-mediated metabolic pathway.

Metab Brain Dis. 2026 Jul 21;41(1)
Authors: An X, Wu D, Wang Y, Ren Z, Yu W
PubMed: 42479245
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Cerebral amyloid angiopathy, brain iron concentrations, and cognitive decline in older people.

Acta Neuropathol. 2026 Jul 21;152(1)
Authors: Agrawal S, Wagner M, Leurgans SE, Agarwal P, van der Weerd L, Bennett DA, Bush AI, Ayton S, Schneider JA
PubMed: 42479178
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The liver-brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications.

Animal Model Exp Med. 2026 Jul 21; Epub 2026 Jul 21
Authors: Zhang N, Chen W, Wang M
PubMed: 42478899
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Projected lecanemab wastage from vial discard: Simulation based on Japanese interim post-marketing surveillance summary statistics.

J Alzheimers Dis. 2026 Jul 21;:13872877261469872. Epub 2026 Jul 21
Authors: Sato K, Niimi Y, Ihara R, Iwata A, Iwatsubo T
PubMed: 42478671
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Linguistic and cultural adaptation of the Montreal Cognitive Assessment (MoCA) version 8 for the Tamil-speaking population in India.

Appl Neuropsychol Adult. 2026 Jul 21;:1-11. Epub 2026 Jul 21
Authors: Porrselvi AP, Sneha CR, Nurul Mehnaz MG, Ravi S, Gopalan R
PubMed: 42482310
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Personalized non-invasive combined magnetic and electrical stimulation of the default mode network in mild AD patients (CMES-AD): a multicentric randomized sham-controlled trial protocol.

Alzheimers Res Ther. 2026 Jul 21; Epub 2026 Jul 21
Authors: Bonnì S, Esposito R, Mencarelli L, Di Lorenzo F, Ricci F, Di Iulio F, Savastano E, Candeo F, De Masi F, Coletta A, Vinci AC, Ferraresi M, Mancini M, Casula EP, Borghi I, Spampinato DA, Maiella M, Cinnera AM, Assogna M, Bruno M, Nocilli M, Ferrara M, Russo M, Tagliamonte NL, Ferrari C, Bertino S, Calabrò RS, Maggio MG, De Luca R, Burrascano R, Gjonaj E, Mirabile A, De Pasquale P, d'Avella A, Quartarone A, Koch G
PubMed: 42482244
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A systematic review and meta synthesis of barriers and facilitators to Black women's participation in healthcare research.

BMC Med Res Methodol. 2026 Jul 21; Epub 2026 Jul 21
Authors: Hall SS, Clancy G, Patel S, Thorpe N, Majmudar B, Merriman C, Agyapong S, Usman J, Henshall C
PubMed: 42481959
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The centrosome-cilium-centriolar satellite axis in neurodegenerative diseases.

EMBO Rep. 2026 Jul 21; Epub 2026 Jul 21
Authors: Sahin U, Firat-Karalar EN
PubMed: 42481875
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DeepPlaque: a scalable multimodal platform for Aβ pathology and cell analysis in Alzheimer's disease.

EMBO Mol Med. 2026 Jul 21; Epub 2026 Jul 21
Authors: Wong HY, Jin C, Yuen SL, Yang X, Gill SS, Xu J, Lai KP, Fu WY, Gao W, Wang X, Wang J, Cao H, Lv G, Mok KY, Tian R, Fu AK, Chen H, Ip NY
PubMed: 42481826
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Computationally guided design of bioactive nanostructures for targeted clearance of amyloid-β aggregates in Alzheimer's disease.

Nat Nanotechnol. 2026 Jul 21; Epub 2026 Jul 21
Authors: Qi T, Fu J, Wang Y, Zhao M, Zhang Z, Peng W, Liu Q, Liu M, Li S, Duan Q, Wang C, Zhuang J, Yan X, Liu Y, Wang H, Huang X
PubMed: 42481708
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Machine learning based digital assessment of mild cognitive impairment using mouse trajectories during the trail making test.

Sci Rep. 2026 Jul 21; Epub 2026 Jul 21
Authors: Juantorena GE, Capelo G, Leon Vallejos BD, Ibáñez A, Petroni A, Berrios W, Fernández MC, Kamienkowski JE
PubMed: 42481653
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Association of target miRNAs expression in blood plasma and cerebrospinal fluid with Alzheimer's disease biomarkers level and cognitive decline.

Sci Rep. 2026 Jul 21; Epub 2026 Jul 21
Authors: Vogrinc D, Holcar M, Lenassi M, Gregorič Kramberger M, Emeršič A, Čučnik S, Dolžan V, Goričar K
PubMed: 42481587
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Spatial multi-omics identifies early synaptic pruning and context-specific dopaminergic vulnerability in synucleinopathies.

Nat Commun. 2026 Jul 21;17(1)
Authors: Rumpf SL, Strübing FL, Nalbach K, Vargiu CM, Berg G, Lichtenthaler SF, Parchi P, Gao P, Chen W, Brendel M, Gnörich JS, Bernhardt A, Dias Rodrigues L, Höglinger GU, Herms J, Koeglsperger T
PubMed: 42481480
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Dopamine-related alterations in functional brain network dynamic reconfiguration in Parkinson's disease.

NPJ Parkinsons Dis. 2026 Jul 21;12(1)
Authors: Abdolalizadeh A, Burkhardt M, Jahansa P, Gießing C, Witt K, Thiel CM
PubMed: 42481479
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Pre-treatment Perivascular Diffusivity Predicts Amyloid Clearance Rate in Lecanemab-Treated Patients: A Retrospective Cohort Study.

AJNR Am J Neuroradiol. 2026 Jul 21; Epub 2026 Jul 21
Authors: Imbett-Martinez R, Ford JN, Gil NH, Dowling TP, Farzaneh H, Zhu S, Younan CM, Relerford M, Ganem Chagui O, Rohatgi S, Romero JM
PubMed: 42481413
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Retraction notice to "The role and molecular mechanism of α synuclein in Parkinson's disease: A diagnostic model for corneal nerve fiber injury" [Int. J. Biol. Macromol. 306 (2025) 141238].

Int J Biol Macromol. 2026 Jul 21;:153567. Epub 2026 Jul 21
Authors: Guan C, Xu X, Yin P, Niu X, Cui G, Xiao L, Zan K, Xu C
PubMed: 42481327
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Retraction notice to "Molecular structure and protein function of mitochondrial fusion protein Mfn2 alleviate Alzheimer's disease: exercise assisted regulation" [Int. J. Biol. Macromol. 311 (2025) 143696].

Int J Biol Macromol. 2026 Jul 21;:153569. Epub 2026 Jul 21
Authors: Li H
PubMed: 42481306
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Frailty and accelerated dementia onset in genetic, sociodemographic and neuropathologic subgroups.

J Neurol Neurosurg Psychiatry. 2026 Jul 21; Epub 2026 Jul 21
Authors: Strating TR, Haapanen MJ, Ma D, Gordon EH, Rockwood K, Hubbard RE, Ward DD
PubMed: 42481072
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Retigabine alleviates cognitive deficits, decreases neuropathology and activates the AKT/GSK-3β pathway in APP/PS1 transgenic mice.

Behav Brain Res. 2026 Jul 21;514:116391. Epub 2026 Jul 21
Authors: Zhang X, Yang X, Zhuang D, Mu Z, Ju C
PubMed: 42480871
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Macrophage responses to and elevated antibody levels against Chlorovirus ATCV-1 in ALS patients.

Antiviral Res. 2026 Jul 21;253:106491. Epub 2026 Jul 21
Authors: Petro TM, Pattee GL, Esmael A, Agarkova IV, Dunigan DD, Chiodo F, De Castro C, Van Etten JL
PubMed: 42480869
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Glucocerebrosidase rescues alpha-synuclein from amyloid formation in vitro.

J Mol Biol. 2026 Jul 21;:169954. Epub 2026 Jul 21
Authors: Barber M, Muller H, Gilbert RJ, Baldwin AJ
PubMed: 42480764
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Entropy-driven, temperature-responsive, aggregations of cells and macromolecules: erythrocytes and α-synucleins as exemplars.

Biosystems. 2026 Jul 21;267:105900. Epub 2026 Jul 21
Authors: Forsdyke DR
PubMed: 42480754
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Effects of broadband mid-infrared radiation and 1,8-cineole on β-amyloid aggregation: a biophysical characterization of moxibustion-based Alzheimer's therapeutic factors.

Int J Biol Macromol. 2026 Jul 21;376:153610. Epub 2026 Jul 21
Authors: Yuan X, McElroy C, Kengwerere MK, Zhu CF, Qiang W
PubMed: 42480738
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Ankle-worn Accelerometers for Gait Analysis in Individuals with Alzheimer's disease and Mild Cognitive Impairment: Reliability of a Finite State Machine Approach.

Med Eng Phys. 2026 Jul 21; Epub 2026 Jul 21
Authors: Cornish B, Van Ooteghem K, Pieruccini-Faria F, Montero-Odasso M, McIlroy W
PubMed: 42480581
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Senescent cell heterogeneity in brain aging and neurodegenerative disease.

Neuron. 2026 Jul 21; Epub 2026 Jul 21
Authors: Graves SI, Del Cioppo Vasques PV, Baker DJ
PubMed: 42480535
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Alzheimer's disease risk prediction via perceptual deformable attention generative adversarial network with large foundation models.

Med Image Anal. 2026 Jul 21;113:104225. Epub 2026 Jul 21
Authors: Xing Z, Liu Z, Zhang DF, Xie K, Fang J, Bi XA, Liu T
PubMed: 42485924
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Blood-based multimodal biomarker models for differentiating early-onset Alzheimer's disease from frontotemporal dementia: a longitudinal study of early-onset dementia and family members (LEAF) study.

J Neurol. 2026 Jul 20;273(8)
Authors: Kwon HS, Moon SY, Hwang M, Kim HJ, Lee SM, Jung NY, Jang H, Baek JM, Kim MJ, Han MH, Zetterberg H, Blennow K, Apostolova LG, Koh SH, Kim EJ, Longitudinal study of Early-onset dementia And Family members (LEAF) investigators
PubMed: 42472733
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Apolipoprotein E ε4 and type 2 diabetes cooperatively accelerate amyloid beta and tau neurodegeneration.

Eur J Nucl Med Mol Imaging. 2026 Jul 20; Epub 2026 Jul 20
Authors: Chen Y, Li Z, Luo S, Li Z, Jiang Y, Chen K, Wang J, Zhang Z, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42472726
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CSF proteomic pathway alterations and caudate dopamine transporter deficits predict cognitive vulnerability in early Parkinson's disease.

Eur J Nucl Med Mol Imaging. 2026 Jul 20; Epub 2026 Jul 20
Authors: Ruan X, Huang X, Gong J, Shan H, Jiang Z, Zhou Q, Li Y, Wei Y, Li M, Wei X
PubMed: 42472725
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From biomarker expansion to equitable implementation in mild cognitive impairment.

Neurol Sci. 2026 Jul 20;47(8)
Authors: Khan M, Khan T, Tariq A
PubMed: 42472714
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Associations of Ginkgo biloba extract exposure with 12-month cognitive trajectories in amyloid PET-positive mild cognitive impairment and Alzheimer's disease: a pooled retrospective cohort study.

BMC Complement Med Ther. 2026 Jul 20; Epub 2026 Jul 20
Authors: Yang Y, Kwak YT
PubMed: 42477703
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Integrating transcriptome, metabolome and 16S rRNA sequencing to reveal the effect of celastrol on Alzheimer's disease in rats.

Sci Rep. 2026 Jul 20; Epub 2026 Jul 20
Authors: Wang Y, Liu L, Zhang Y, Luo P, Xiang Q, Tang L
PubMed: 42477465
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Microglial states revisited: from homeostasis to disease.

Nat Rev Neurosci. 2026 Jul 20; Epub 2026 Jul 20
Authors: Eggen BJ, Kooistra SM
PubMed: 42477453
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MAPT-derived circTau6 induces tau pathogenesis and neurodegeneration by encoding Tau variants.

Mol Psychiatry. 2026 Jul 20; Epub 2026 Jul 20
Authors: Jiang G, Wang D, Shao L, Mao X, Xiong X, Zhang D, Chen WN, Yuan H, Wang S, Zhang J, Pina-Crespo J, Zhong L, Zhang YW, Zhang J, Xu H, Ming C, Huang TY, Wu X, Lei P, Zhao Y
PubMed: 42477443
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Revisiting the cognitive potential of lithium in alzheimer's disease: the role of cholinergic system and brain connectivity.

Transl Psychiatry. 2026 Jul 20; Epub 2026 Jul 20
Authors: Pini L, Imbimbo BP, Pomara N
PubMed: 42477313
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Dyslipidemia-Induced Mitochondrial Dysfunctions in the Brains Does Not Reach Pathological Levels in the ApoE-Knockout Mice.

Neurochem Res. 2026 Jul 20;51(4)
Authors: Hsu CH, Chu PW, Chen YY, Ho MH, Liao EC, Chen SK
PubMed: 42477232
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Patient-Derived PSEN1 Cerebral Organoids Revealed Parallel Development of Amyloid-β Accumulation and Network Dysfunction.

Cell Mol Neurobiol. 2026 Jul 20; Epub 2026 Jul 20
Authors: Angelovski A, Hribkova H, Sedmik J, Liscakova B, Svecova O, Cesnarikova S, Amruz Cerna K, Pospisilova V, Kral M, Kolajova M, Klimes P, Bohaciakova D, Bebarova M
PubMed: 42477212
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Complement dysregulation during the early phases of synucleinopathy.

Acta Neuropathol. 2026 Jul 20;152(1)
Authors: Khan H, Gifford M, Kordbacheh A, Bury A, Panoushek S, Cole-Strauss A, Kemp CJ, Luk KC, Steece-Collier K, Kuhn NC, Kanaan NM, Sortwell CE, Patterson JR, Benskey MJ
PubMed: 42477211
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Plasma proteome profiling identified biomarkers for the differential diagnosis and molecular staging of neurodegenerative dementias.

Nat Aging. 2026 Jul 20; Epub 2026 Jul 20
Authors: Bellomo G, Vermunt L, In 't Veld S, Doecke JD, Hok-A-Hin YS, Veverová K, Houtkamp IM, Alcolea D, Halbgebauer S, Quesada C, Mattsson N, Martinez-Castillo M, López-Martínez MJ, Rábano A, Boonkamp L, Fowler C, Fortea J, Gaetani L, Toja A, Pijnenburg Y, Lemstra A, van der Flier WM, Sánchez-Juan P, Hort J, Otto M, Anderl-Staub S, Sieben A, de Viel B, Engelborghs S, Hansson O, Masters C, Lleó A, Parnetti L, Teunissen CE, Del Campo M
PubMed: 42477094
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Alzheimer's Disease: A Review of Molecular Mechanisms and Interventions Targeting Aβ-Binding Receptors.

ACS Chem Neurosci. 2026 Jul 20; Epub 2026 Jul 20
Authors: Jia M, Mei J, Guan Y, Wang Z, Ai H
PubMed: 42476928
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Corrigendum to "Network meta-analysis of different traditional Chinese medicine therapies as adjuvant treatments for Alzheimer's disease" [Compl. Ther. Clin. Pract. 64 (2026) 102075].

Complement Ther Clin Pract. 2026 Jul 20;:102078. Epub 2026 Jul 20
Authors: Li Z, Bai X, Li J, Geng W, Xing X, Liang J, Li J, Li J
PubMed: 42476847
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Multimodal Imaging of Tau Pathology and Network Connectivity Dynamics Across the Alzheimer's Continuum: A Pilot Study Using Second-Generation Tracer [18F]MK6240.

Acad Radiol. 2026 Jul 20; Epub 2026 Jul 20
Authors: Piao S, Wang J, He K, Wang N, Liu X, Yang L, Xie F, Li Y, Bao Y
PubMed: 42476833
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Early treatment with naproxen alters hippocampal metabolites in the TgF344-AD rat model of Alzheimer's disease.

Neurochem Int. 2026 Jul 20;:106226. Epub 2026 Jul 20
Authors: Fowler CF, Osipyan E, Devenyi GA, Madularu D, Breitner J, Near J
PubMed: 42476460
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Exploring shared genetic pathways and gene interplay in major neurodegenerative diseases: a comprehensive review.

Gene. 2026 Jul 20;1010:150318. Epub 2026 Jul 20
Authors: Pattnaik PP, Prusty SK, Pati S, Jew KA, Bora AK, Sahoo J, Sahu PK
PubMed: 42476327
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Unlocking new uses: The promise of antidepressants in treating Alzheimer's and Parkinson's through Neuroinflammation modulation.

Prog Neuropsychopharmacol Biol Psychiatry. 2026 Jul 20;:111848. Epub 2026 Jul 20
Authors: Abbaszadeh F, Amini NB, Davoody S, Rezaei M, Ghasemi R, Javadpour P
PubMed: 42476282
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Decoding lactate signals in Alzheimer's disease: redox control, receptor pharmacology, lactylation chemistry, and neuroglial vulnerability.

Biochem Pharmacol. 2026 Jul 20;253(Pt 1):118275. Epub 2026 Jul 20
Authors: Zaman W, Ayaz A, Ullah A
PubMed: 42476266
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Mitochondrial capsules: A revolutionary organelle therapy for mitochondrial and neurodegenerative diseases.

Mol Ther. 2026 Jul 20; Epub 2026 Jul 20
Authors: Zhang Y, Yang X, Wei M
PubMed: 42476134
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Brain Region-Centered MultiModal Hypergraph Fusion for MCI Conversion Prediction.

IEEE J Biomed Health Inform. 2026 Jul 20;PP Epub 2026 Jul 20
Authors: Dong Z, Liu H, Ge X, Zhang H, Li Z, Chen Y, Li W
PubMed: 42475211
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Environmental Risk in Parkinson Disease-Bring the Noise.

JAMA Neurol. 2026 Jul 20; Epub 2026 Jul 20
Authors: Yang D, Elser HC, Willis AW
PubMed: 42475105
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Road Traffic Noise, Noise Difference Between Residential Facades, and Risk of Parkinson Disease.

JAMA Neurol. 2026 Jul 20; Epub 2026 Jul 20
Authors: Sørensen M, Poulsen AH, Raaschou-Nielsen O, Thygesen LC, Brandt J, Andersen C, Münzel T
PubMed: 42475104
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Substantia Nigra Susceptibility-To-Volume Ratio Derived From QSM as a Marker for Discrimination of Progressive Supranuclear Palsy From Parkinson's Disease and Multiple System Atrophy.

J Magn Reson Imaging. 2026 Jul 20; Epub 2026 Jul 20
Authors: Candan HE, Jo S, Myratgeldyyev N, Tessema AW, Lee H, Lee JH, Lee H, Lee GY, Suh CH, Ryu J, Chung SJ, Park K, Lee EJ, Cho H
PubMed: 42475080
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Neuroprotective potential of marine-derived polysaccharide against Aβ42-induced toxicity in a Drosophila Alzheimer's disease model.

Mol Biol Rep. 2026 Jul 20;53(1)
Authors: Kale D, Dcunha BV, Lakshmi S, Raghu SV, Elumalai P
PubMed: 42474786
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Use of blood-based neurofilament light chain as an endpoint in clinical trials of neurodegenerative conditions: a scoping review.

J Neurol. 2026 Jul 20;273(8)
Authors: Zheng Y, Bhalala OG, Chin KS, Watson R, Yassi N
PubMed: 42474734
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Neural network-enhanced investigation of ferroptosis and druggability in early-onset alzheimer's disease.

Metab Brain Dis. 2026 Jul 20;41(1)
Authors: Singh P, Rath SL
PubMed: 42474555
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[18F]FDG PET outperforms MRI for detecting early tau-related neurodegeneration.

Eur J Nucl Med Mol Imaging. 2026 Jul 20; Epub 2026 Jul 20
Authors: Vourkas O, Zhang L, Jimenez-Pérez A, Sánchez-Martín C, Fernández-Álvarez M, Rabano A, Sánchez-Juan P, Silva-Rodríguez J, Grothe MJ, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42474503
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"Has your Memory Been Letting you Down?" Use of Figurative Language Modulates Expression of Awareness of Impairments in Alzheimer's Disease.

J Geriatr Psychiatry Neurol. 2026 Jul 20;:8919887261469563. Epub 2026 Jul 20
Authors: Santos de Carvalho RL, Dos Santos LA, Ferrison J, Bomilcar I, Bertrand E, Dourado MC, Morris RG, Mograbi DC
PubMed: 42474486
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Early- and late-life brain reserve proxies and their interactions with education on cognitive outcomes in older adults: A population-based MRI study.

J Alzheimers Dis. 2026 Jul 20;:13872877261469556. Epub 2026 Jul 20
Authors: Han X, Li Y, Wang J, Liu X, Cao E, Song Y, Song L, Cong L, Zhang Q, Tang S, Wang Y, Du Y, Qiu C
PubMed: 42474305
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Disease burden of Alzheimer's disease and other dementias in older adults.

J Alzheimers Dis. 2026 Jul 20;:13872877261469808. Epub 2026 Jul 20
Authors: Tong Y, Lv X, Liu J, Cheng Z, Wang J, Hua W, Li R, Zheng J, Guo G, Tang S
PubMed: 42474304
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Return of genetic results to persons with Parkinson's disease: Blessing or foe?

J Parkinsons Dis. 2026 Jul 20;:1877718X261470605. Epub 2026 Jul 20
Authors: Shiner T, Alcalay RN
PubMed: 42474300
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From mild cognitive impairment to moderate Alzheimer's disease: Associations between decision-making capacity and awareness.

J Alzheimers Dis. 2026 Jul 20;:13872877261468737. Epub 2026 Jul 20
Authors: Pereira De Souza NA, Belfort Almeida Dos Santos TT, Lima Nogueira MM, Dourado MC
PubMed: 42474295
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Long-term locus coeruleus stimulation exacerbates tau pathology in PS19 mice.

J Alzheimers Dis. 2026 Jul 20;:13872877261468577. Epub 2026 Jul 20
Authors: Nong Y, Wellman S, Zhang H, Liu YA, Argyrousi EK, Arancio O, Wang Q
PubMed: 42474291
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Brain iron, cortical atrophy and cognition impairment in cerebral amyloid angiopathy: A quantitative susceptibility mapping study.

J Alzheimers Dis. 2026 Jul 20;:13872877261469524. Epub 2026 Jul 20
Authors: Fang S, Sha Y, Zhou Y, Sun G, Li E, Yao M, Zhou L, Zhu Y, Peng B, Ni J
PubMed: 42474289
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Stage-Dependent β-Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease.

Ann Clin Transl Neurol. 2026 Jul 20; Epub 2026 Jul 20
Authors: Ay U, Alaylioglu M, Sahin E, Oner SS, Iskan G, Cakan GC, Kizilates-Evin G, Hari E, Kurt E, Dursun E, Bilgic B, Hanagasi H, Gurvit H, Demiralp T, Gezen-Ak D, Samanci B
PubMed: 42473913
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Microbes and Microbial Chemical Matter in the Seeding of Alzheimer's Disease: Prospects for Orthogonal Therapies.

ACS Chem Neurosci. 2026 Jul 20; Epub 2026 Jul 20
Authors: Kumar N, Yarlagadda V
PubMed: 42478074
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Correction: A rare missense variant impacting NEK1 kinase function is associated with ALS.

Acta Neuropathol Commun. 2026 Jul 20;14(1)
Authors: Brenner D, Ponomarenko A, Petrut I, Beyrle S, Contardo M, Loss I, Radke C, Frank J, Zimmer E, Schlesner M, Achenbach P, Scheveneels W, Aly A, Nazlican H, Hesebeck-Brinkmann J, Oeckl P, Müller K, Siebert R, Böckers T, van Eijk K, Veldink J, Kleger A, Mulaw M, Andersen PM, Forsberg K, Weishaupt JH, Loghmani SB, Grehl T, van Damme P, Weis J, Catanese A
PubMed: 42477825
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Unraveling the role of lipid metabolism in ALS risk: a Mendelian randomization analysis using GWAS data.

Orphanet J Rare Dis. 2026 Jul 20; Epub 2026 Jul 20
Authors: Zhang H, Li C, Yu J, Liang Y, Wu Y, Cao F
PubMed: 42477767
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Cognitive dysfunction in Parkinson's disease: Hippocampal vulnerability and redox-driven mechanisms.

Redox Biol. 2026 Jul 20;96:104318. Epub 2026 Jul 20
Authors: Curto AR, Silva AA, Fiadeiro MB, Pereira D, Cristóvão AC
PubMed: 42485748
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Taming arbitrary modality missingness and imbalance: A unified graph-MoE framework for Alzheimer's disease diagnosis.

Med Image Anal. 2026 Jul 20;113:104222. Epub 2026 Jul 20
Authors: Yang G, Du Y, Hu X, Shi W, Yang M, Wang S, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42492404
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Association of α-synuclein seed-amplification kinetics with cognitive decline in idiopathic Parkinson's disease.

Parkinsonism Relat Disord. 2026 Jul 20;150:108856. Epub 2026 Jul 20
Authors: Rodriguez-Antiguedad J, Puig-Davi A, Ruiz-Barrio I, Campo-Caballero D, Vacchi E, Melli G, Bojtos L, Franch-Marti C, Olmedo-Saura G, Vazquez-Oliver A, Martinez-Horta S, Kulisevsky J, Pagonabarraga J
PubMed: 42492163
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Distribution of Big Tau Isoforms in the Human Central and Peripheral Nervous System.

Ann Neurol. 2026 Jul 19; Epub 2026 Jul 19
Authors: Koppisetti RK, Barthélemy NR, Horie K, Ly CV, Roberts KF, Koutarapu S, Perrin RJ, Franklin EE, Pedicone C, Orrick J, Melendez J, Miller TM, Sato C, Ghoshal N, Goate AM, Karch CM, Bateman RJ, Mukherjee S
PubMed: 42473039
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Neurotheranostics in Alzheimer's Disease: Current concepts and experimental strategies.

Pharmacol Ther. 2026 Jul 19;286:109084. Epub 2026 Jul 19
Authors: Yanagisawa D, Ohgita T, Kawashima H, Yoshikawa H, Saito H, Tooyama I, Takata K
PubMed: 42472573
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Association Between Plasma Phosphorylated Tau-217 and Cognition in Parkinson's Disease.

Mov Disord. 2026 Jul 19; Epub 2026 Jul 19
Authors: Kouchache T, Chan T, Sun S, Liu L, Delva A, Gan-Or Z, Rosa-Neto P, Gagnon JF, Dagher A, Postuma RB, Sharp M
PubMed: 42473272
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Unlocking the Dynamics of Human SPPL2a: First Atomistic Characterization of an Alzheimer's-Linked Intramembrane Protease.

J Chem Inf Model. 2026 Jul 19; Epub 2026 Jul 19
Authors: Dutta S, Singh MK, Dehury B
PubMed: 42473207
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Development of Aryl Cyano Amides for Fluorescence Discrimination of Tau and Amyloid Beta Deposits in Tissue.

ACS Chem Neurosci. 2026 Jul 19; Epub 2026 Jul 19
Authors: Jessup RE, Ehrlich RS, Teppang KL, Dasgupta S, Sigurdson CJ, Yang J
PubMed: 42473091
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Personality traits and blood-based biomarkers of neurodegeneration and astrogliosis.

Neurobiol Aging. 2026 Jul 19;168:37-43. Epub 2026 Jul 19
Authors: Terracciano A, Karakose S, Luchetti M, O'súilleabháin PS, Stephan Y, Sutin AR
PubMed: 42485867
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AQP4-dependent enhancement of glymphatic function attenuates tau pathology and neurodegeneration in PS19 mice.

Mol Neurodegener. 2026 Jul 18; Epub 2026 Jul 18
Authors: Yamada K, Ishida K, Sakamoto A, Shimada H, Watanabe M, Shimojo M, Igarashi H, Iwatsubo T
PubMed: 42471719
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Multimodal molecular mapping of the vasculature in human cortex reveals lipid markers of cerebral amyloid angiopathy.

Acta Neuropathol Commun. 2026 Jul 18; Epub 2026 Jul 18
Authors: Marshall CR, Moser FA, Scott CF, Ventura-Antunes L, Romero-Fernandez W, Migas ŁG, Tideman LE, Colley ME, Dufresne M, Schrag MS, Van de Plas R, Spraggins JM
PubMed: 42471701
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Tau pathology and depression interact to accelerate driving decline in cognitively normal older adults.

Mol Psychiatry. 2026 Jul 18; Epub 2026 Jul 18
Authors: Zhu Y, Brown DC, Chen C, Singh RK, Bekena S, Ances BM, Lenze EJ, Carr DB, Trani JF, Babulal GM
PubMed: 42471447
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DNA Sensing and Neuroinflammation: Mechanistic Insights into cGAS-STING Biology and Therapeutic Translation in Age-Related Neurodegenerative Diseases.

Mol Neurobiol. 2026 Jul 18;63(1)
Authors: Ahmad A, Khan MM
PubMed: 42471426
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PatientSpace: A multimodal graph-based latent representation framework for modeling neurodegenerative disease heterogeneity.

Neuroimage. 2026 Jul 18;338:122136. Epub 2026 Jul 18
Authors: Manouvriez D, Kuchcinski G, Lecerf S, Lahousse H, Rogeau A, Villain N, Kas A, Pyatigorskaya N, Nguyen M, Petrovic S, Cole JH, Zabihi M, Hache B, Bertoux M, Lebouvier T, Roca V, Lopes R, Alzheimer’s Disease Neuroimaging Initiative, Frontotemporal Lobar Degeneration Neuroimaging Initiative, MEMENTO study group, SOCRATES study group
PubMed: 42471130
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Neurovascular unit senescence as a driver of blood-brain barrier dysfunction in Alzheimer's disease：Mechanisms, consequences, and therapeutic implications.

Ageing Res Rev. 2026 Jul 18;121:103260. Epub 2026 Jul 18
Authors: Yao M, Liu A, Xing L, Song J, Yang Y, Yue X, Li H
PubMed: 42471087
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STAT3 mediated the isoleucine-induced Alzheimer's disease progression.

Brain Res. 2026 Jul 18;:150472. Epub 2026 Jul 18
Authors: Liu Y, Li Y, Zhou Y, Hei Y, Wang S, Bajpai AK, Chang X, Wang X, Xu F, Yao C
PubMed: 42471077
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Ginkgo biloba extract 50 alleviates memory and synaptic plasticity deficits by inhibiting neuroinflammation via the blockage of ATP-P2X7R axis in presenilin 1/2 conditional double knockout mice.

J Ethnopharmacol. 2026 Jul 18;372:122199. Epub 2026 Jul 18
Authors: Hu K, Gao W, Pan J, Xu X, You P, Li K, Yang G, Wang D, Jiang M, Wang X, Zhao Y, Xu Y
PubMed: 42471071
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Therapeutic potential of curcumin in Alzheimer's disease: Multi-target mechanisms of action, experimental and clinical evidence, safety aspects.

Biomed Pharmacother. 2026 Jul 18;202:119776. Epub 2026 Jul 18
Authors: Aydoğdu GS, Ağagündüz D, Roviezzo F, Romano B, Capasso R
PubMed: 42470923
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Associations of Insulin Sensitivity with Risk of All-Cause and Cause-Specific Dementia: A Prospective Cohort Study.

Mol Neurobiol. 2026 Jul 18;63(1)
Authors: Fu Y, Gao PY, Xu W, Tan L
PubMed: 42470526
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Conformational Bifurcation of Tau R3-R4 Oligomers Underlies Fibril Polymorphism.

Biophys J. 2026 Jul 18; Epub 2026 Jul 18
Authors: Zhang T, Dai L, Ma Y, Xu S, Liu X, Zhao M, Li W, Wang J, Liu Y
PubMed: 42471758
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A Novel p. (Leu173del) Mutation in the Presenilin 1 (PSEN1) Gene in Two Sisters with Dominantly Inherited Alzheimer's Disease.

Intern Med. 2026 Jul 18; Epub 2026 Jul 18
Authors: Fujii S, Takahashi-Iwata I, Matsushima M, Yaguchi H, Takatsuka A, Hara N, Ikeuchi T, Yabe I
PubMed: 42476773
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Multi-threshold polygenic risk improves hippocampal-based cognitive decline prediction.

Genome Med. 2026 Jul 17; Epub 2026 Jul 17
Authors: Janahi M, Lorenzini L, Oxtoby NP, Barkhof F, Mokrab Y, Schott JM, Altmann A, Initiative FT
PubMed: 42469913
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Metabolic reprogramming via SIRT2-deficient microglial large extracellular vesicles ameliorates alzheimer's pathology.

J Neuroinflammation. 2026 Jul 17; Epub 2026 Jul 17
Authors: Tang X, Chen R, Xing J, Huang Q, Luo L, Ouyang C, Ma F, Wen J, Zhang J, Kong L, Cai Y, Wang Y, Cui L
PubMed: 42469846
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Secretory leukocyte protease inhibitor (SLPI) attenuates TLR4/NF-κB-mediated neuroinflammation in amyotrophic lateral sclerosis: a candidate molecule associated with neuro-pathology.

Mol Med. 2026 Jul 17; Epub 2026 Jul 17
Authors: Li MA, Song YZ, Li T, Wu J, Tao Y, Hu R, Qiao CM, Cui C, Zhao WJ, Shen YQ
PubMed: 42469634
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Perivascular Spaces as Determinants of Amyloid, Tau, and Vascular Biomarker Progression.

Ann Neurol. 2026 Jul 17; Epub 2026 Jul 17
Authors: Low A, Gunter JL, Hu M, Raghavan S, Przybelski SA, Schwarz CG, Kantarci K, Lowe VJ, Petersen RC, Graff-Radford J, Jack CR Jr, Vemuri P
PubMed: 42469606
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Nanomedicine targeting neuroinflammatory pathways in Alzheimer's disease: a new frontier in inflammopharmacology.

Inflammopharmacology. 2026 Jul 17; Epub 2026 Jul 17
Authors: Kaushik S, Fatima JE, Raheem A, Barbhuiya MA, Thirupathi AT, Singh LP, Khan PA, Aparna TN, Pramanik S, Shahid MA
PubMed: 42469568
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Neuropathological correlates of imaging in dementia with Lewy bodies.

J Neural Transm (Vienna). 2026 Jul 17; Epub 2026 Jul 17
Authors: Walker L, Attems J, Donaghy P
PubMed: 42469559
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CD33 and clusterin interact biophysically and genetically to modulate Alzheimer risk.

Nat Commun. 2026 Jul 17; Epub 2026 Jul 17
Authors: Dodd RB, Enomoto M, Zhou Y, Satoh K, Zhang Y, Chen F, Acheson B, Ghaffari D, Sayn-Wittgenstein E, Manning JJ, Dukas GV, Patel R, Burguete AS, Kralovec MJ, Rashid M, Hall JL, Tamucci KA, Chatila Z, Liu M, Lee AJ, Vardarajan BN, Taga MF, Pollari S, Rabinovitch A, Rillahan CD, Bobkov AA, Sergienko E, Meadows W, Qamar S, Randle SJ, Johnson CM, Sevalle J, Griffin J, Bohm C, Ikura M, Xian X, Herz J, Kelly MA, West J, Satapathy S, Wilson MR, Javitch JA, Fraser PE, Bennett DA, De Jager PL, Fishelson Z, Frenkel D, Asher WB, Bradshaw EM, George-Hyslop PS
PubMed: 42469217
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Clinicopathological and molecular heterogeneity of amyloid-β in unnatural deaths under 70 years: A forensic autopsy-based study.

Brain Pathol. 2026 Jul 17;:e70124. Epub 2026 Jul 17
Authors: Ichimata S, Hata Y, Yoshida K, Tanaka R, Murayama S
PubMed: 42469165
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Alzheimer's drug lecanemab: FDA approves easier initial use, with "huge implications" for UK.

BMJ. 2026 Jul 17;394:e100318.
Authors: Baraniuk C
PubMed: 42468989
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Focused ultrasound blood brain barrier opening for targeted therapeutics in neurodegenerative diseases.

Biol Psychiatry. 2026 Jul 17; Epub 2026 Jul 17
Authors: Halabian N, Park C, Omoto L, Bocca LF, Palacios G, Wu K, Hamani C, Rabin J, Abrahao A, Davidson B, Lipsman N, Meng Y
PubMed: 42468901
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Frailty-related plasma proteomic signatures and key biomarkers for new-onset dementia and its subtypes: A prospective cohort study.

J Adv Res. 2026 Jul 17; Epub 2026 Jul 17
Authors: Zhang X, Huang Q, Huang J, Zhang P, Feng X, Li Z, Raper DM, Mao C
PubMed: 42468803
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Air-Liquid interface midbrain organoids model the pathological features of Parkinson's disease.

Neuroscience. 2026 Jul 17; Epub 2026 Jul 17
Authors: Kälvälä S, Abushik P, Rezaie M, Dougalis A, Koistinaho J, Gardberg M, Luk KC, Malm T, Pelkonen A, Lehtonen Š
PubMed: 42468771
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Is Urolithin A(UA) a pharmacologically credible neuro-nutraceutical? A critical review of mechanisms, brain exposure, and evidence gaps in Alzheimer's and Parkinson's disease.

Neurochem Int. 2026 Jul 17;199:106224. Epub 2026 Jul 17
Authors: Girish Oswal D, Rane M
PubMed: 42468665
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Polygonatum sibiricum polysaccharides and Alzheimer's disease: A review of preparation, structure, mechanisms, and application.

Fitoterapia. 2026 Jul 17;193:107393. Epub 2026 Jul 17
Authors: Li M, Zhao Y, Xu B, Wang L, Luo W, Tan R, Zhang X, Jiang H
PubMed: 42468644
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Brain organoids in Parkinson's disease drug development: Human-specific models for translational discovery.

Drug Discov Today. 2026 Jul 17;:104742. Epub 2026 Jul 17
Authors: Zagare A, Jarazo J, Schwamborn J
PubMed: 42468620
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Targeting neuroinflammation and neurodegeneration in Parkinson's disease: Emerging natural and synthetic therapeutic strategies.

Ageing Res Rev. 2026 Jul 17;121:103263. Epub 2026 Jul 17
Authors: Arbab S, Ullah H, Han Y, Zhou J, Ka L
PubMed: 42468577
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Connecting mechanistic roles of vitamins in dementia: An overview on translational insights from preclinical models to clinical promise.

Ageing Res Rev. 2026 Jul 17;121:103262. Epub 2026 Jul 17
Authors: Karmakar V, Ghosh A, Majie A, Chatterjee K, Gorain B
PubMed: 42468576
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FUS-driven zebrafish model of ALS identifies tribenzylamine as a candidate modulator of ALS-associated pathology.

Biomed Pharmacother. 2026 Jul 17;202:119761. Epub 2026 Jul 17
Authors: Seo Y, Lee J, Lee Y, Kim S, Lee JS, Ro H, Cho SH, Park JS, Kim MJ, Park HC
PubMed: 42468211
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Reduced serum IL-6 as a potential peripheral marker of amnestic mild cognitive impairment: A pilot study.

Med Clin (Barc). 2026 Jul 17;166(9):107540. Epub 2026 Jul 17
Authors: Castro MM, Pavón RA, Moroni AD, Melcon M, Menite NE, Villafañe G, Genaro AM, Palumbo ML
PubMed: 42468194
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Baseline and placebo-related imaging, cerebrospinal fluid, plasma biomarker, and cognitive findings in unimpaired PSEN1 E280A mutation carriers and non-carriers in the Alzheimer's Prevention Initiative Autosomal Dominant Alzheimer's Disease Colombia Trial.

EBioMedicine. 2026 Jul 17;130:106390. Epub 2026 Jul 17
Authors: Bittner T, Lopera F, Rios-Romenets S, Schiffman C, Clayton D, Hibar D, Kollmorgen G, Dolton M, Poon V, Nguyen J, Giraldo-Chica M, Acosta-Baena N, Espinosa A, Villegas G, Muñoz C, Serna L, Alvarez S, Protas H, Luo J, Sohankar J, Chen Y, Ghisays V, Malek-Ahmadi M, Ashton NJ, Denkinger MN, Cai Y, Xu YR, Ostaszewski B, Selkoe DJ, Alexander RC, Quiroz YT, Su Y, Chen K, Doody RS, Langbaum JB, Tariot PN, Sink KM, Reiman EM
PubMed: 42468111
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Therapeutic Gene Editing of APOE4 in Sporadic Alzheimer's Disease via Prime Editor 7.

Adv Sci (Weinh). 2026 Jul 17;:e76658. Epub 2026 Jul 17
Authors: Kim Y, Lee G, An S, Park H, Kim H, Kim J, Kang S, Kim S, Kwon D, Park J, Hwang Y, Kim S, Yuan X, Jeong J, Lee H, Kim HK, Kim J
PubMed: 42467931
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SORLA up-regulation suppresses pathological effects in aged tauopathy mouse brain.

Sci Adv. 2026 Jul 17;12(29):eaed6825. Epub 2026 Jul 17
Authors: Huang H, Shi CH, Yang W, Piña-Crespo JC, Bhatnagar J, Curatolo J, Murad R, Shah P, Campos A, Houser A, Porritt RA, Van Vo G, Xiao Q, Zhang T, Feng S, Yip KY, Huang TY
PubMed: 42467771
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Healthy Dietary Patterns Linked to Lower Dementia Risk, Study Finds.

JAMA. 2026 Jul 17; Epub 2026 Jul 17
Authors: Anderer S
PubMed: 42467441
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Resveratrol and neuroprotection: modulation of cellular dynamics and signaling networks in neurodegenerative diseases.

Inflammopharmacology. 2026 Jul 17; Epub 2026 Jul 17
Authors: Hassan MA, Al Amin M, Sweilam SH, Abohassan M, Krishnan K, Gupta JK, Jahnavi P, Vodeti R, Radha R, Gupta PS, Reddy KT
PubMed: 42467293
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Association of the miR-146a rs57095329 polymorphism with susceptibility and clinical phenotypes in Parkinson's disease.

Neurogenetics. 2026 Jul 17;27(1)
Authors: Chen G, Zhang Y, Wang T
PubMed: 42467290
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A novel writing to dictation test to investigate lexical and sublexical processes: Italian normative data and preliminary clinical feasibility in Mild Cognitive Impairment and Alzheimer's disease.

Neurol Sci. 2026 Jul 17;47(8)
Authors: Feder B, Polli G, Laurenzi S, Righetti S, Tessari B, Terruzzi S, Papagno C
PubMed: 42467268
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18F-flortaucipir PET imaging: Biodistribution in the Japanese population and diagnostic accuracy by Japanese readers.

Ann Nucl Med. 2026 Jul 17; Epub 2026 Jul 17
Authors: Imabayashi E, Morris A, Iaccarino L, Arora AK, Kamiki E, Lu M
PubMed: 42467182
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Targeting Sirtuin Signaling in Parkinson's Disease and Neurodegeneration: Molecular Insights and Translational Potential.

Mol Neurobiol. 2026 Jul 17;63(1)
Authors: Kumari S, Singh H, Vaidya S, Taliyan R
PubMed: 42467143
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Clinical dissociation and electromyographic convergence of paratonia in cognitive impairment including Alzheimer's disease: Evidence for a shared central inhibitory mechanism.

J Alzheimers Dis. 2026 Jul 17;:13872877261468799. Epub 2026 Jul 17
Authors: Marinelli L, Puce L, Diotti D, Currà A, Vestito L, Mori L, Ponzano M, Cervia A, Cotellessa F, Schenone C, Monacelli F, Trompetto C
PubMed: 42466721
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Resting-state functional dynamics alterations relate to plasma amyloid markers and statistically explain memory impairments in the TgF344-AD model of Alzheimer's disease.

Alzheimers Res Ther. 2026 Jul 17; Epub 2026 Jul 17
Authors: Al-Awlaqi A, Berckmans L, De Waegenaere S, Vanherle S, Griffis J, Dewachter I, Verhoye M, Adhikari MH
PubMed: 42464353
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A bibliometric analysis of research trends and mechanisms of olfactory dysfunction in Alzheimer's diseases from 2008 to 2024.

Medicine (Baltimore). 2026 Jul 17;105(29):e49799.
Authors: Li X, Li L, Ren Y, Shi L, Sun M, Liu Z
PubMed: 42469972
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Utility of the Short Cognitive and Neuropsychiatric Assessment Scale (ShoCo) in a multiethnic Asian cohort of patients with progressive supranuclear palsy.

Parkinsonism Relat Disord. 2026 Jul 17;150:108852. Epub 2026 Jul 17
Authors: Chen KK, Yap KH, Lim TQ, Wong ES, Tee JW, Lee AL, Lim DW, Tee YX, Lim YZ, Fernandiz JC, Beh YY, Tay YW, Toh TS, Schee JP, Han WH, Lit LC, UM (University of Malaya) PSP Study Group, Matar E, Tan AH, Lim SY
PubMed: 42475925
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Irreversible mechanical weakening of amyloid-β K16 mutants via electrostatic torque.

Bioelectrochemistry. 2026 Jul 17;173:109394. Epub 2026 Jul 17
Authors: Shin H, Lim S, Yeom J, Jeong HC, Yoon T
PubMed: 42475908
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Combining MRI-Derived Imaging Measures and Peripheral Proteomics to Improve the Mechanistic Understanding of Alzheimer's Disease Beyond Core Pathology: A Scoping Review.

Curr Alzheimer Res. 2026 Jul 17; Epub 2026 Jul 17
Authors: Li OY, Herrera Guerra D, Anthony M, Oh K, Vankee-Lin F, Turnbull A
PubMed: 42474022
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Therapeutic Effects of the Traditional Chinese Formula Qifuyin on Cognition, Lipid Metabolism, and Gut Microbiota in ApoE4 Mice.

Comb Chem High Throughput Screen. 2026 Jul 17; Epub 2026 Jul 17
Authors: Yu Y, Zhao H, He Y, Zhao J, Yang X, Liu X, Cheng X
PubMed: 42474014
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Plasma Total and Phosphorylated α-Synuclein as Biomarkers in Multiple System Atrophy: A Multicenter Study.

Curr Neuropharmacol. 2026 Jul 17; Epub 2026 Jul 17
Authors: Yuan X, Wan L, Chen Z, Wang C, Long Z, Chen D, Peng L, Ouyang R, Wu X, Dong X, Long X, Du K, Qiu R, Tang B, Jiang H
PubMed: 42474003
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The multifaceted roles of IL-1β in Alzheimer's disease: From pathogenic amplifier to neuroimmune modulator.

Cytokine Growth Factor Rev. 2026 Jul 17;91:82-98. Epub 2026 Jul 17
Authors: Pilat D, Baranger K, Rivera S
PubMed: 42492417
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Peripheral inflammation impairs glymphatic function, contributing to neurodegeneration in Alzheimer's disease.

iScience. 2026 Jul 17;29(7):116581. Epub 2026 Jun 30
Authors: Xie B, Liu J, Hao Y, Fu X, Yang S, Guo C, Yang Y
PubMed: 42491578
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Hospital Budget Impact and Provider-Side Economic Evaluation of Lecanemab and Donanemab Under Japan's National Fee Schedule: A Head-to-Head Linear Model.

Value Health Reg Issues. 2026 Jul 16;:101675. Epub 2026 Jul 16
Authors: Makita K, Nishihara T, Arakaki Y, Ohida T, Goto K, Kutsuna N
PubMed: 42467046
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RETRACTED: Alluri et al. Repurposing Diltiazem for Its Neuroprotective Anti-Dementia Role Against Intra-Cerebroventricular Streptozotocin-Induced Sporadic Alzheimer's Disease-Type Rat Model. Life 2023, 13, 1688.

Life (Basel). 2026 Jul 16;16(7)
Authors: Alluri R, Kilari EK, Pasala PK, Kopalli SR, Koppula S
PubMed: 42464798
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Blood-based immunophenotyping of T cell profiles in patients with neurodegenerative disorders.

Alzheimers Res Ther. 2026 Jul 16; Epub 2026 Jul 16
Authors: Malichova F, Swann P, Kigar SL, Savinykh Yarkoni N, Goddard J, Lai KO, Chouliaras L, Surendranathan A, Turner L, Savulich G, Bevan-Jones R, Ashton NJ, Blennow K, Zetterberg H, Needham E, Jones J, McEwan WA, Rowe JB, O'Brien JT, Malpetti M
PubMed: 42464410
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Transplantation of human iPSC-derived microglia ameliorates neuropathology and circuit dysfunction in progranulin-deficient mice.

Mol Neurodegener. 2026 Jul 16; Epub 2026 Jul 16
Authors: Davtyan H, Naguib S, Voskobiynyk Y, Chadarevian JP, Capocchi JK, Giacchino JL, Eskandari-Sedighi G, DeNittis V, Ford JB, Agababian A, Nguyen J, Chadarevian AL, Sutherland MS, Shabestari SK, Tran K, Holt B, Nana AL, Zhang J, Spina S, Wong MY, Grinberg LT, Seeley WW, Huang E, Clelland CD, Gong S, Fan L, Paz JT, Blurton-Jones M, Gan L
PubMed: 42464356
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Passive amyloid-β immunotherapy in Alzheimer's disease: a multicellular clearance system beyond plaque removal.

Mol Neurodegener. 2026 Jul 16;21(1)
Authors: Zhan X, Liu C, Yu C, Lindblom N, Deierborg T, Kobro-Flatmoen A, Gouras GK, Wen G
PubMed: 42464289
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Change in Amyloid-β Deposition and Diffusion Tensor Image Analysis along the Perivascular Space Index in Incident Neurodegenerative Disease.

Ann Neurol. 2026 Jul 16; Epub 2026 Jul 16
Authors: Lim S, Lee Y, Yun CS, Kim K, Yun CH, Alzheimer's Disease Neuroimaging Initiative
PubMed: 42464008
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Cardiovascular Comorbidities with Alzheimer's Disease: A Systematic Review and Meta-analysis.

Curr Alzheimer Res. 2026 Jul 16; Epub 2026 Jul 16
Authors: Rodrigues JF, Rodrigues LP, Rodrigues FC, Cavalcante LL, Payão SL, Tavares AR, Forlenza OV, de Godoy MF, Filho GM
PubMed: 42473227
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Relationship Between miRNA and Neurodegenerative Diseases Such as Alzheimer's disease, Parkinson's, Huntington's disease, Amyotrophic Lateral Sclerosis.

Mini Rev Med Chem. 2026 Jul 16; Epub 2026 Jul 16
Authors: Keskin A, Mogulkoc R, Baltaci AK
PubMed: 42473218
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Frontal and temporal hyper-perfusion in Parkinson's disease with subjective cognitive decline.

Parkinsonism Relat Disord. 2026 Jul 16;150:108853. Epub 2026 Jul 16
Authors: Takeda K, Shima A, Nishida A, Kambe D, Furukawa K, Sakamaki-Tsukita H, Yoshimura K, Wada I, Sakato Y, Terada Y, Sawamura M, Nakanishi E, Taruno Y, Yamakado H, Fushimi Y, Okuchi S, Nakamoto Y, Matsumoto R, Takahashi R, Sawamoto N
PubMed: 42480237
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When algorithms speak first: The public health risk of consumer AI in ALS diagnosis.

J Neurol Sci. 2026 Jul 15;:126098. Epub 2026 Jul 15
Authors: Mathis S, Le Masson G
PubMed: 42476836
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Metal-organic macrocycles as molecular modulators of amyloid-β aggregation and cytotoxicity.

Chem Sci. 2026 Jul 15; Epub 2026 Jul 15
Authors: Na C, Gupta G, Kim M, Choe Y, Lee J, Lee CY, Lim MH
PubMed: 42483155
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Impact of Vitamin B12, Folate and Homocysteine in Modulating Cognitive Functions and the Brain's White Matter Hyperintensity in Alzheimer's Disease.

Ann Neurosci. 2026 Jul 15;:09727531261457693. Epub 2026 Jul 15
Authors: Sah RP, Cs V, Jayaram S, Yadav AK, Pereira P, Damodaran J
PubMed: 42491066
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Merocyanine derivatives as theranostic agents for cognitive improvement and real-time imaging of amyloid-β in APP/PS1 transgenic mice.

Spectrochim Acta A Mol Biomol Spectrosc. 2026 Jul 15;363(Pt 1):128458. Epub 2026 Jul 15
Authors: Li X, Li S, Su J, Zheng F, Li S, Zhao X, Chen D, Yan J, Xia C
PubMed: 42486010
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Comparison of sleep characteristics between Alzheimer's disease dementia and Parkinson's disease dementia.

Sleep Med. 2026 Jul 14;147:109140. Epub 2026 Jul 14
Authors: Zhao B, Shang S, Zhang M, Guo X, Zhou R, Qu Q, Cao H
PubMed: 42468248
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Exosomes in Neurodegenerative Disorders: Isolation Strategies, Therapeutic Potential, and Clinical Trials.

CNS Neurol Disord Drug Targets. 2026 Jul 14; Epub 2026 Jul 14
Authors: Bhukta S, Palei NN, Jaiswal V, Mishra A, M P
PubMed: 42483921
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Bioactive compounds from traditional Chinese medicine for mitochondrial dysfunction-oriented nanodelivery in neurodegenerative diseases.

Phytomedicine. 2026 Jul 14;159:158590. Epub 2026 Jul 14
Authors: Cheng T, Hao W, Li M, Yang Y, Rao Z, Yang W
PubMed: 42486042
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Targeting Aβ25-35-Induced Neuronal Senescence-Like Features Using Curcumin-Loaded Solid Self-Emulsifying Drug Delivery Systems.

Curr Aging Sci. 2026 Jul 13; Epub 2026 Jul 13
Authors: Lonlab K, Nitjapol A, Thummayot S, Tiyaboonchai W, Jumnongprakhon P
PubMed: 42487594
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Caudate-Predominant Striatal Dopaminergic Deficit Distinguishes Behavioral Variant of Frontotemporal Dementia With Parkinsonism From Other Parkinsonian Syndromes.

Clin Nucl Med. 2026 Jul 8; Epub 2026 Jul 8
Authors: Feng L, Liu W, Zhao YX, Chan KW, Shen Q, Li XY, Lu JY, Ge JJ, Zuo CT, Wang J, Wang J, Liu FT
PubMed: 42474399
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Heterostructure nanozyme-synergistically modulated electrochemiluminescence/photoelectrochemical sensing platform for detection of Alzheimer's disease biomarkers in plasma samples.

Biosens Bioelectron. 2026 Jul 7;312:119004. Epub 2026 Jul 7
Authors: Feng Q, Song Y, Pan Z, Liu W, Xu H, Wang L, Cheng H, Wang P, Chen G
PubMed: 42468094
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Association of hypoxic burden with brain atrophy in Alzheimer's disease.

J Neurol Sci. 2026 Jul 6;489:126088. Epub 2026 Jul 6
Authors: Rollo E, Tafuri B, Tamburrino L, Urso D, Giugno A, Vilella D, Zecca C, De Blasi R, Gnoni V, Logroscino G
PubMed: 42470846
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Rising burden of Alzheimer's mortality linked to hypertension: A U.S. population-based study, 1999-2023.

J Natl Med Assoc. 2026 Jul 3; Epub 2026 Jul 3
Authors: Faheem MS, Hassan ST, Najmi OE, Waheed A, Ullah ZB, Sattar Y, Alraies MC
PubMed: 42493280
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Recent breakthroughs in blood-based biomarkers of Alzheimer disease: opportunities and challenges in older adults.

Age Ageing. 2026 Jul 2;55(7)
Authors: Dyer AH, Dolphin H, Roitto HM, O'Connor A, Welsh TJ, Kennelly SP
PubMed: 42476554
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Development of a Novel Blood-Based Assay for Brain-Derived Tau and Its Validation in Traumatic Brain Injury.

J Neurochem. 2026 Jul;170(7):e70518.
Authors: Balogun WG, Zeng X, Nafash MN, Sehrawat A, Shi R, Svirsky SE, Okonkwo DO, Puccio AM, Karikari TK
PubMed: 42470153
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Development and characterization of a novel TDP-43 positron emission tomography tracer: [18F]JNJ-TDP43-1.

Alzheimers Dement. 2026 Jul;22(7):e71675.
Authors: Xia CA, Salarian M, Gartshore CJ, Scaglione A, Hayes T, Liu S, Tsai HM, Echavarren J, Cid JM, Matzeu A, Szardenings AK
PubMed: 42471754
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The design of embedded pragmatic clinical trials: methodological developments and statistical lessons learned from the first cycle of the NIA IMPACT collaboratory.

Alzheimers Dement. 2026 Jul;22(7):e71660.
Authors: Travison TG, Davis-Plourde K, Goldfeld KS, Li F, Lou Y, Monin JK, Taljaard M, Turner J, Vranceanu AM, Allore HG
PubMed: 42471753
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Variations in Amyloid PET Positivity Among Patients With Different Alzheimer's Disease Subtypes.

Geriatr Gerontol Int. 2026 Jul;26(7):e70646.
Authors: Hanyu H, Sano M, Koyama Y, Momose T, Watanabe S
PubMed: 42476630
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Spousal Dementia Exposure and Risk of Dementia.

JAMA Netw Open. 2026 Jul 1;9(7):e2624175.
Authors: Wang SH, Lin MC, Fan CC, Huang WL, Hsu CC, Wu CS
PubMed: 42475091
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A gradual and sustainable approach to diagnosing sleep and circadian disturbances in dementia.

Alzheimers Dement. 2026 Jul;22(7):e71654.
Authors: Guarnieri B, Hoxhaj D, Buracchi Torresi F, Arnaldi D, Bonanni E, Carpi M, Cremascoli R, Liguori C, Lombardi G, Mainieri G, Provini F, Silvestri R, Puligheddu M, Tassoni MM
PubMed: 42473871
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Brain aging patterns among nine neurological disorders: A case-control study.

PLoS Med. 2026 Jul;23(7):e1004860. Epub 2026 Jul 21
Authors: Liang C, Pearlson G, Bustillo J, Kochunov P, Chen J, Zhang X, Jiang R, Hutchison KE, Sui J, Fu Z, Yang X, Du Y, Zhang D, Qi S, Calhoun VD
PubMed: 42479667
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A phase-II randomized controlled pilot study of nicotinamide riboside supplementation in older adults with amnestic mild cognitive impairment.

Alzheimers Dement. 2026 Jul;22(7):e71605.
Authors: Martens CR, Decker KP, DeConne TM, Sanjana F, Horvat F, Rizzi NA, Awad C, Habash E, Hobson JC, Kramer MK, Armstrong ML, Reisdorph N, Pohlig RT, Lanzi AM, Johnson CL, Cohen ML, Ellison JM
PubMed: 42478598
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Relationships of CSF biomarkers to cortical atrophy in early-onset Alzheimer's disease.

Alzheimers Dement. 2026 Jul;22(7):e71479.
Authors: Touroutoglou A, Katsumi Y, Hensel J, Schindler SE, Ibanez L, Brickhouse M, Eloyan A, Eckbo R, Zaitsev A, La Joie R, Thangarajah M, Taurone A, Vemuri P, Jack CR Jr, Hammers DB, Foroud T, Aisen P, Beckett L, Koeppe R, Kukull WA, Toga A, Atri A, Clark D, Day GS, Duara R, Graff-Radford NR, Grant IM, Honig LS, Johnson EC, Jones DT, Masdeu JC, Mendez MF, Musiek E, Onyike CU, Riddle M, Rogalski E, Salloway S, Sha S, Turner RS, Wingo TS, Wolk DA, Womack K, Carrillo MC, Rabinovici GD, Apostolova LG, Dage JL, Dickerson BC, Eldaief MC, LEADS Consortium
PubMed: 42477860
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Prognostic value of plasma %p-tau217 in cognitively unimpaired older adults.

Alzheimers Dement. 2026 Jul;22(7):e71599.
Authors: Silva-Rodríguez J, Zhang L, Kleineidam L, López-González FJ, Wagner-Reguero S, Martínez-Castillo M, Sogorb-Esteve A, Guamán-Chulunchana ME, Pastor AB, Moreno N, Ruiz-Calvo A, Sánchez-Martín C, Alfayate E, Molero-Cartón M, Valeriano-Lorenzo EL, Frades-Payo B, Valentí M, Zea-Sevilla MA, Moscoso A, Ramírez A, Martino-Adami P, Riedel-Heller SG, Scherer M, Jeromin A, Calero M, Del Ser T, Schneider A, Grothe MJ, Sánchez-Juan P
PubMed: 42483984
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Loss of Neocortical Oligodendrocytes in Parkinson's Disease Patients-A Stereological Study.

J Neurosci Res. 2026 Jul;104(7):e70146.
Authors: Horndrup MP, Salvesen L, Kaalund SS, Olesen MV
PubMed: 42482628
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Risk Factors for the Diagnosis of Progressive Supranuclear Palsy in the UK Biobank.

Mov Disord. 2026 Jul;41(7):1727-1739. Epub 2026 Mar 24
Authors: Zhao CW, Dale M, Pantelyat A, Tartaglia MC, Schneider RB, Coughlin DG, Rodriguez-Porcel F, Wszolek Z, Xie T, Golbe LI, Rowe JB, Wills AM
PubMed: 42481001
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Anchored kinase and phosphatase signaling networks in amyloid β-induced synaptic dysfunction.

Mol Pharmacol. 2026 Jul 1;108(8):100141. Epub 2026 Jul 1
Authors: Koek L, Jo HN, Kennedy MJ, Dell'Acqua ML
PubMed: 42480386
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Comment on "The Relationship Between Voluntary Rapid Blinking Rate and Future Development of Neurodegenerative Disease".

Geriatr Gerontol Int. 2026 Jul;26(7):e70704.
Authors: Zhang W, Hu C
PubMed: 42493471
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Prolonged systemic inflammation worsens impairments to astrocyte Ca2+ and functional hyperemia in Alzheimer's disease.

Alzheimers Dement. 2026 Jul;22(7):e71607.
Authors: Liu C, Sakha K, Anton J, Cardenas-Rivera A, Yaseen MA
PubMed: 42489215
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Computational Evaluation of Oleuropein Interactions with Alzheimer's Disease-Related Proteins Using Molecular Docking and Molecular Dynamics.

J Vis Exp. 2026 Jun 30;(232)
Authors: Elshekh A, Abdelmaguid AM, Eltanany RM, El-Kordy YH, Khedr AA, Mekkawy SA, El-Khadragy MF, Albrakati A, Abdelfattah MS, Abdel Moneim AE
PubMed: 42475419
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Serum miR-423-5p discriminates patients with Parkinson's disease from healthy individuals and is associated with severity and the risk of cognitive dysfunction.

Clin Neurol Neurosurg. 2026 Jun 30;270:109558. Epub 2026 Jun 30
Authors: Chen P, Wang W, Chen H, Ye F
PubMed: 42492311
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Artificial intelligence-based automated scoring of the Clock Drawing Test in older adults in primary care: association with Mini-Mental State Examination scores, discriminative performance, and agreement with clinician rating.

Fam Pract. 2026 Jun 11;43(4)
Authors: Tutu ÖG, Bilen V, Ziroğlu Z
PubMed: 42488980
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Dr. David Perlmutter: New Steps to Targeting Brain Health and Alzheimer's Disease.

Integr Med (Encinitas). 2026 Jun;25(3):38-43.
Authors: Baker S
PubMed: 42491623
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One-Year Substantia Nigra Changes across Parkinson's Disease Stages.

Mov Disord. 2026 Apr 27; Epub 2026 Apr 27
Authors: Coussediere C, Pereira B, Devos D, Lehéricy S, Peran P, Durand E, Chassain C, Houeto JL, Benatru I, Colin O, Rascol O, Ory-Magne F, Brefel-Courbon C, Maindreville AD, Vidailhet M, Corvol JC, Frismand S, Schmitt E, Defebvre L, Carriere N, Meissner WG, Boraud T, Remy P, Moro E, Thobois S, Geny C, Bonny JM, Durif F, Marques A, MPI‐R2* study group
PubMed: 42474124
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[Contributions of seeding amplification assays to the diagnosis of synucleinopathies].

Med Sci (Paris). 2026;42(6-7):600-607. Epub 2026 Jul 17
Authors: Lamard E, Bougard D
PubMed: 42466689
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Integrating serum pharmacology, network pharmacology, and molecular biology analysis to reveal the mechanisms of Baihe Dihuang decoction in treating Alzheimer's disease.

Front Microbiol. 2026;17:1765044. Epub 2026 Jul 2
Authors: Liang X, Ning T, Wang Y, Zhan L
PubMed: 42466122
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RETRACTION: A Severe Alzheimer's Disease Patient Improved by Intravenous Mesenchymal Stem Cell Transplant.

Case Rep Neurol Med. 2026;2026:9873498. Epub 2026 Jul 16
Authors: Medicine CR
PubMed: 42466090
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Exercise-conditioned extracellular vesicles in Alzheimer's disease: a multi-organ signaling network linking peripheral adaptation to brain pathology.

Front Immunol. 2026;17:1856546. Epub 2026 Jul 2
Authors: Zhang R, Chen K
PubMed: 42465741
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Development and efficacy of ex vivo expanded autologous regulatory T cells for the treatment of amyotrophic lateral sclerosis.

Front Immunol. 2026;17:1854252. Epub 2026 Jul 2
Authors: You Y, Zhu H, Zhang Q, Wang J, Dong C, Yang Z, Zhang J, Zhang Y, Zhang M, Lu M, Du C
PubMed: 42465739
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Neuroplasticity and immune system are related to altered grey matter networks: a cohort study in sporadic Alzheimer's disease.

Brain Commun. 2026;8(4):fcag257. Epub 2026 Jul 8
Authors: de Leeuw DM, Duits FH, Dicks E, Vromen EM, Teunissen CE, Barkhof F, van der Flier WM, Visser PJ, Tijms BM
PubMed: 42465730
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Implications of autolysosome- astrocyte-associated signature in the pathogenesis of Alzheimer's disease: evidence from artificial intelligence and multi-omics and clinical validation.

Front Neurosci. 2026;20:1867831. Epub 2026 Jul 2
Authors: Zhang C, Song D
PubMed: 42465724
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Chronic stress, cortisol dysregulation, and neurodegenerative vulnerability: mechanistic pathways linking HPA-axis dysfunction to Alzheimer's disease risk.

Front Aging Neurosci. 2026;18:1883880. Epub 2026 Jul 2
Authors: Almalki DF, Alkabkabi RA, Wayyani RA, Alharthi AS, Aljuhani HA, Mahyub RM, Bakhsh HS, Alomani AM, Almhmadi NN, Aljohani AA, Tawakul AA
PubMed: 42465698
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Glymphatic dysfunction in Alzheimer's disease: a systematic review and meta-analysis of the DTI-ALPS index as an imaging biomarker.

Front Aging Neurosci. 2026;18:1832525. Epub 2026 Jul 2
Authors: Wu Y, Zhang C, Yan J, Lin L, Tian Y, Fu Z, Sun X
PubMed: 42465697
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Exosomal gene-based predictive model and therapeutic target identification for Alzheimer's disease: A bioinformatics analysis.

PLoS One. 2026;21(7):e0354014. Epub 2026 Jul 20
Authors: Ma L, Wang D, Li Z, Ye G, Chen M
PubMed: 42475384
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Soluble high-molecular-weight amyloid-β species derived from amyloid-β-laden brains induce cerebral β-amyloidosis.

Brain Commun. 2026;8(4):fcag188. Epub 2026 Jul 20
Authors: Kashiwagi-Hakozaki M, Uchigami H, Naka Y, Kokawa A, Mano T, Cho J, Yamada K, Miyashita A, Hara N, Ikeuchi T, Serrano-Pozo A, Frosch MP, Hyman BT, Toda T, Fukayama M, Ushiku T, Wakabayashi T, Iwatsubo T, Hashimoto T
PubMed: 42473637
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Cerebrospinal fluid α-synuclein and Aβ42 link with default mode and salience networks connectivity in dementia with Lewy bodies.

Alzheimers Dement (N Y). 2026;12(3):e70266. Epub 2026 Jul 18
Authors: Gabriel V, Chabran E, Sourty M, Cretin B, Philippi N, Muller C, Anthony P, Demuynck C, de Sousa PL, Botzung A, Sanna L, Bousiges O, Blanc F
PubMed: 42473545
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Feature integration of [18F]FDG PET brain imaging using deep learning for sensitive cognitive decline detection.

PLoS One. 2026;21(7):e0341995. Epub 2026 Jul 21
Authors: Lee Y, Kim S, Kim S, Kang Y, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42479708
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Association of triglyceride-glucose index (TyG) and a body shape index (ABSI) with cognitive decline and dementia risk.

PLoS One. 2026;21(7):e0354418. Epub 2026 Jul 22
Authors: Yang S, Cui L, Zhang J, Yang Y, Huo J, Ding Y, Zhang J, He S, Li J
PubMed: 42485421
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Up regulated hippocampal insulin pathway and oxidative stress are related to opposite changes in olfaction and episodic memory in a compensatory metabolic syndrome model in rats.

Front Cell Neurosci. 2026;20:1845387. Epub 2026 Jul 7
Authors: Clavel-Pérez PI, Phillips-Farfán BV, Camacho-Castillo L, Calderón-Garcidueñas AL, Carvajal K
PubMed: 42483706
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Association of gait, balance, and fall risk with dementia in Down syndrome: a systematic review of the literature.

Dement Neuropsychol. 2026;20:e20250442. Epub 2026 Jul 20
Authors: da Conceição AS, Fonseca LM, Forlenza OV
PubMed: 42483691
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From cognitive screening to digital phenotyping: rethinking early detection of cognitive impairment in primary care.

Front Neurol. 2026;17:1870463. Epub 2026 Jul 7
Authors: Altuna M
PubMed: 42483443
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Impacts of DNA ligase I genotypes on Taiwan Parkinson's disease.

Biomedicine (Taipei). 2026;16(2):17-23. Epub 2026 Jun 1
Authors: Chen CH, Chang WS, Tsai CW, Bau DT, Hsu SW, Hong KT, Tsai CH, Tsai FJ, Lu MK, Yang JS
PubMed: 42483441
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Correction: Vascular endothelial growth factor receptor-1 (VEGFR-1) knock-down is protective against hypoxia, Aβ1-42 oligomer and Aβ1-42 fibril-induced neuronal cell death: implications in AD pathogenesis.

Front Neurosci. 2026;20:1901421. Epub 2026 Jul 7
Authors: Angom RS, Li Z, Rachamala HK, Castanedes-Casey M, Kulkarni T, Chakravarty T, Dutta S, Wang E, Dickson D, Mukhopadhyay D, Das P
PubMed: 42483224
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Unveiling the structural insights and inhibitory potential of coumarin-1,2,3-triazole hybrids against BACE1: a promising approach for Alzheimer's disease therapy.

Front Chem. 2026;14:1824875. Epub 2026 Jul 7
Authors: Almostafa M, Ali I, Yahya G, Siddiqi AR
PubMed: 42482698
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Dynamic, state-dependent characteristics of cognitive fluctuations in Lewy body dementia: a magnetoencephalography study.

Brain Commun. 2026;8(4):fcag236. Epub 2026 Jun 24
Authors: Sadeqi H, Ahmadi B, Morshedizad Z, Burke R, Patel B, McFarland NR, Armstrong MJ, Babajani-Feremi A
PubMed: 42491938
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A deep residual attention-Recurrent model for early and multi-stage Alzheimer's disease detection.

Front Aging Neurosci. 2026;18:1798861. Epub 2026 Jun 26
Authors: Munipalli UM, Annepu V
PubMed: 42491893
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Nonlinear L-shaped association between composite dietary antioxidant index and risk of dementia: a prospective cohort study.

Front Public Health. 2026;14:1839421. Epub 2026 Jul 3
Authors: Luo C, Wang R, Yang F, Qin L, Ren Y, Guo M, Cai H, Feng S, Li N, Gao H, Tang Y, Chen Q
PubMed: 42491583
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Antibody screening identifies HERV-K-related immune responses as candidate biomarkers in Parkinson's disease.

Front Cell Infect Microbiol. 2026;16:1838615. Epub 2026 Jul 3
Authors: Simula ER, Fais M, Ercoli T, Jasemi S, Paulus K, Solla P, Pandino C, Sechi LA
PubMed: 42491523
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Multitype hand writing as a digital marker for Parkinson's disease.

Clin Park Relat Disord. 2026;15:100480. Epub 2026 Jul 2
Authors: Liu H, Deng H, Wang L, Wang X, Mo M
PubMed: 42491273
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Visual read performance of 18F-Florbetapir and 18F-NAV4694 Aβ PET compared against Centiloid reference standard in a paired cohort.

Alzheimers Dement (Amst). 2026;18(3):e70426. Epub 2026 Jul 16
Authors: Paranawithana I, Doré V, Bourgeat P, Poon A, Toh HB, Thientunyakit T, Kaewchur T, Sutherland A, Gillman AG, Huang K, Feizpour A, Fripp J, Villemagne VL, Rowe CC
PubMed: 42491111
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Associations between neuronavigated rTMS-mediated functional connectome plasticity and neurotransmitter receptors in Alzheimer's disease.

Alzheimers Dement (N Y). 2026;12(3):e70294. Epub 2026 Jul 16
Authors: Yao W, Lv T, Zheng W, Liu Y, Shi X, Zhang Y, Song Y, Bai Y, Bai F
PubMed: 42491022
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Real-world pharmacovigilance for anti-Aβ therapies using a large language model.

Alzheimers Dement (Amst). 2026;18(3):e70412. Epub 2026 Jul 16
Authors: Fong A, Tabaie A, Paylor S, Tran T, Iqbal R, Ratwani RM, Zafari Z, Bangerter LR, Brandt NJ
PubMed: 42490993
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Six-month real-world amyloid PET outcomes after lecanemab: Greater amyloid reduction at the MCI stage than in dementia.

Alzheimers Dement (N Y). 2026;12(3):e70300. Epub 2026 Jul 16
Authors: Kim GH, Yoon HJ, Kim EH, Kim JY, Yeom J, Kang SY, Lee B, Jeong JH
PubMed: 42490986
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Short-term psychological impacts of Alzheimer's disease risk disclosure based on blood-biomarker results.

Alzheimers Dement (N Y). 2026;12(3):e70295. Epub 2026 Jul 16
Authors: Ramamurthy B, Cho A, Abdolmaleki M, Fayez N, Roby D, Maynard KB, Jefferson AL, Bolton C
PubMed: 42490982
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GLP-1 receptor agonists in Parkinson's disease: a meta-analysis revealing motor benefit and highlighting mood improvement.

Front Neurol. 2026;17:1858507. Epub 2026 Jul 3
Authors: Chen Y, Zhang Z, Liu Z, Lv T, Ye M, Yan J, Zhang M
PubMed: 42490867
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Substantia Nigra MRI markers are lower in Alzheimer's disease and are linked to general cognitive function.

Brain Commun. 2026;8(4):fcag238. Epub 2026 Jun 24
Authors: Krohn F, Sarkar M, Schütze H, Iliopoulos P, Penalba-Sánchez L, Hämmerer D, Yakupov R, Lüsebrink F, Spottke A, Schneider A, Roy N, Incesoy E, Heneka M, Kilimann I, Kleineidam L, Teipel SJ, Brosseron F, Goerss D, Glanz W, Schmid M, Rostamzadeh A, Wagner M, Fliessbach K, Jessen FO, Düzel E, Betts MJ
PubMed: 42488758
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Distinct brain regions are affected by neurodevelopmental or pre-dementia changes in Down syndrome.

Brain Commun. 2026;8(4):fcag269. Epub 2026 Jul 13
Authors: Jorge L, Oliveira J, Martins R, Lopes T, Quental H, Castelo-Branco M
PubMed: 42488757
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BDNF-amyloid-β Axis in Alzheimer's disease: molecular mechanisms and therapeutic perspectives.

Front Mol Neurosci. 2026;19:1884003. Epub 2026 Jul 8
Authors: Liu F, Huang Y, Wang A, Liu P, Wu H, Fan H
PubMed: 42488724
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A whole-transcriptome analysis of differentially expressed genes, transcripts, and transcript usage in blood samples from Parkinson's disease patients.

Exp Biol Med (Maywood). 2026;251:11099. Epub 2026 Jul 8
Authors: Koks S, Muldmaa M, Price J, Whiley L, Jakobson M, Singleton L, Howting D, Pfaff AL, Chopra A, Watson M, Sikk K, Taba P
PubMed: 42488690
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Autoimmune signatures in neurodegenerative dementias: from peripheral immune activation to CNS pathology.

Front Immunol. 2026;17:1893167. Epub 2026 Jul 8
Authors: Zhao X, Zhang G, Wang Z, Zhang D, Xia Z, Huo C
PubMed: 42488639
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Modeling Alzheimer's disease with brain organoids: mechanisms, applications, and future directions.

Front Cell Dev Biol. 2026;14:1791272. Epub 2026 Jul 8
Authors: Zhao Q, Li S, Ju Y, Kong X, Liu X
PubMed: 42488555
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Difficulty with taking medications and the future risk of Alzheimer's disease and related dementias: Health and Retirement Study of Americans.

Am J Neurodegener Dis. 2026;15(1):1-15. Epub 2026 Apr 15
Authors: Hajihosseini S, Panahandeh E, Rashidi A, Soleimani K, Parvandi F, Rostami N, Mottaghi H, Rahmani S, Belbasi M, Bideshki F, Faramin Lashkarian M, Ebrahimi MA, Alizadeh H
PubMed: 42488516
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Nutritional substrates and microglial metabolic fitness in brain aging and Alzheimer's disease: from lipid handling to TREM2-linked translation.

Front Nutr. 2026;13:1886340. Epub 2026 Jul 8
Authors: Li Z, Ming Q, Fu L, Yang J, Lv Y, Chen B, Lu Z
PubMed: 42488212
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Geographic and demographic gaps in publicly available Alzheimer's disease datasets: A large language model-based discovery and analysis.

Digit Health. 2026;12:20552076261470698. Epub 2026 Jul 21
Authors: Singhal M, Lin J, Delehanty M, Karimi A, Rittner L, Bento M
PubMed: 42488183
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Optimizing Alzheimer's prediction with dental care: comparing robust deep learning models in health and retirement study of America.

Am J Neurodegener Dis. 2026;15(2):16-24. Epub 2026 Jun 25
Authors: Taheri H, Musaie F, Mohammadzadeh N, Tavassoli Naini P, Novin N, Salimi O, Amini A, Malekpour H, Panahiyan P, Malek M, Fathiazar A, Namadkolahi R
PubMed: 42488179
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Automated MoCA scoring for Arabic speakers using hybrid AI of multimodal speech, vision, and LLM integration.

Front Psychol. 2026;17:1833118. Epub 2026 Jul 8
Authors: Rabaya YJ, Qarariya SA, Abualhaija TM, Salah AA, Ashqar HI
PubMed: 42488041
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