Alzforum - Papers of the Week: 4-10 May 2012

Development and Advanced Validation of an Optimized Method for the Quantitation of Aβ(42) in Human Cerebrospinal Fluid.

AAPS J. 2012 May 3;
Authors: Cullen VC, Fredenburg RA, Evans C, Conliffe PR, Solomon ME
PubMed: 22552903
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Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome.

Age (Dordr). 2012 May 4;
Authors: Wood SH, Craig T, Li Y, Merry B, de Magalhães JP
PubMed: 22555619
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Radioactive agent approved as part of Alzheimer disease workup.

Am J Health Syst Pharm. 2012 May 15;69(10):818
Authors: Thompson CA
PubMed: 22555074
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Postoperative cognitive decline: where art tau?

Anesthesiology. 2012 Apr;116(4):751-2
Authors: Eckenhoff RG, Planel E
PubMed: 22343470
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An Asymmetric Dimer as the Basic Subunit in Alzheimer's Disease Amyloid β Fibrils.

Angew Chem Int Ed Engl. 2012 May 8;
Authors: Lopez Del Amo JM, Schmidt M, Fink U, Dasari M, Fändrich M, Reif B
PubMed: 22565601
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Molecular signatures of ALS disease progression in hind and forelimb muscles of a SOD1G93A mouse model.

Antioxid Redox Signal. 2012 May 7;
Authors: Capitanio D, Vasso M, Ratti A, Grignaschi G, Volta M, Moriggi M, Daleno C, Bendotti C, Silani V, Gelfi C
PubMed: 22563797
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Effect of purpose in life on the relation between Alzheimer disease pathologic changes on cognitive function in advanced age.

Arch Gen Psychiatry. 2012 May;69(5):499-504
Authors: Boyle PA, Buchman AS, Wilson RS, Yu L, Schneider JA, Bennett DA
PubMed: 22566582
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Midlife vs Late-Life Depressive Symptoms and Risk of Dementia: Differential Effects for Alzheimer Disease and Vascular Dementia.

Arch Gen Psychiatry. 2012 May;69(5):493-8
Authors: Barnes DE, Yaffe K, Byers AL, McCormick M, Schaefer C, Whitmer RA
PubMed: 22566581
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Lysosomal dysfunction in neurodegeneration: The role of ATP13A2/PARK9.

Autophagy. 2012 Jun 1;8(6)
Authors: Usenovic M, Krainc D
PubMed: 22561922
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Antagonizing Effects of Soybean Isoflavones on β-amyloid Peptides- induced Oxidative Damage in Neuron Mitochondria of Rats.

Basic Clin Pharmacol Toxicol. 2012 May 3;
Authors: Feng JF, He LL, Li D, Yuan LH, Yu HL, Ma WW, Yang Y, Xi YD, Ding J, Xiao YX, Xiao R
PubMed: 22551092
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Adult-onset focal expression of mutated human tau in the hippocampus impairs spatial working memory of rats.

Behav Brain Res. 2012 Apr 25;
Authors: Mustroph ML, King MA, Klein RL, Ramirez JJ
PubMed: 22561128
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Rapid degradation kinetics of amyloid fibrils under mild conditions by an archaeal chaperonin.

Biochem Biophys Res Commun. 2012 Apr 30;
Authors: Kurouski D, Luo H, Sereda V, Robb FT, Lednev IK
PubMed: 22564742
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Peptidylarginine deiminase modulates the physiological roles of enolase via citrullination: links between altered multifunction of enolase and neurodegenerative diseases.

Biochem J. 2012 May 2;
Authors: Jang B, Jeon YC, Choi JK, Park M, Kim JI, Ishigami A, Maruyama N, Carp RI, Kim YS, Choi EK
PubMed: 22551201
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Structural Dynamics of the Amyloid β-Protein Monomer Folding Nucleus.

Biochemistry. 2012 May 7;
Authors: Roychaudhuri R, Yang M, Condron MM, Teplow DB
PubMed: 22551351
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Specific binding of a ß-cyclodextrin dimer to the amyloid ß peptide modulates the peptide aggregation process.

Biochemistry. 2012 May 3;
Authors: Wahlström A, Cukalevski R, Danielsson J, Jarvet J, Onagi H, Rebek J, Linse SS, Gräslund A
PubMed: 22554145
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Cholesterol-depletion corrects APP and BACE1 misstrafficking in NPC1-deficient cells.

Biochim Biophys Acta. 2012 Apr 19;
Authors: Malnar M, Kosicek M, Lisica A, Posavec M, Krolo A, Njavro J, Omerbasic D, Tahirovic S, Hecimovic S
PubMed: 22551668
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Evaluation of sialic acid-analogs for the attenuation of amyloid-beta toxicity.

Biochim Biophys Acta. 2012 Apr 30;
Authors: Dhavale D, Henry JE
PubMed: 22565051
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Inhibitory effect of curcumin on the Al(III)-induced Aβ(42) aggregation and neurotoxicity in vitro.

Biochim Biophys Acta. 2012 Apr 25;
Authors: Jiang T, Zhi XL, Zhang YH, Pan LF, Zhou P
PubMed: 22561904
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The small molecule inhibitor PR-619 of deubiquitinating enzymes affects the microtubule network and causes protein aggregate formation in neural cells: Implications for neurodegenerative diseases.

Biochim Biophys Acta. 2012 Apr 28;
Authors: Seiberlich V, Goldbaum O, Zhukareva V, Richter-Landsberg C
PubMed: 22565157
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Tumor Necrosis Factor Gene Variation Predicts Hippocampus Volume in Healthy Individuals.

Biol Psychiatry. 2012 May 2;
Authors: Baune BT, Konrad C, Grotegerd D, Suslow T, Ohrmann P, Bauer J, Arolt V, Heindel W, Domschke K, Schöning S, Rauch AV, Sehlmeyer C, Kugel H, Dannlowski U
PubMed: 22554453
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Multiscale Adaptive Marginal Analysis of Longitudinal Neuroimaging Data with Time-Varying Covariates.

Biometrics. 2012 May 2;
Authors: Skup M, Zhu H, Zhang H
PubMed: 22551084
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An olfactory 'stress test' may detect preclinical Alzheimer's disease.

BMC Neurol. 2012 May 2;12(1):24
Authors: Schofield PW, Ebrahimi H, Jones AL, Bateman GA, Murray SR
PubMed: 22551361
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NF-kappaB p50 subunit knockout impairs late LTP and alters long term memory in the mouse hippocampus.

BMC Neurosci. 2012 May 3;13(1):45
Authors: Oikawa K, Odero GL, Platt E, Neuendorff M, Hatherell A, Bernstein MJ, Albensi BC
PubMed: 22553912
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How the FDA forgot the evidence: the case of donepezil 23 mg.

BMJ. 2012;344:e1086
Authors: Schwartz LM, Woloshin S
PubMed: 22442352
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5-HT(6) receptor agonists and antagonists enhance learning and memory in a conditioned emotion response paradigm by modulation of cholinergic and glutamatergic mechanisms.

Br J Pharmacol. 2012 May 9;
Authors: Woods S, Clarke NN, Layfield R, Fone KC
PubMed: 22568655
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Amyloid burden and metabolic function in early-onset Alzheimer's disease: parietal lobe involvement.

Brain. 2012 May 3;
Authors: Ossenkoppele R, Zwan MD, Tolboom N, van Assema DM, Adriaanse SF, Kloet RW, Boellaard R, Windhorst AD, Barkhof F, Lammertsma AA, Scheltens P, van der Flier WM, van Berckel BN
PubMed: 22556189
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Chronic traumatic encephalopathy: neurodegeneration following repetitive concussive and subconcussive brain trauma.

Brain Imaging Behav. 2012 May 3;
Authors: Baugh CM, Stamm JM, Riley DO, Gavett BE, Shenton ME, Lin A, Nowinski CJ, Cantu RC, McKee AC, Stern RA
PubMed: 22552850
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Longitudinal change in neuropsychological performance using latent growth models: a study of mild cognitive impairment.

Brain Imaging Behav. 2012 May 6;
Authors: Johnson JK, Gross AL, Pa J, McLaren DG, Park LQ, Manly JJ, For the Alzheimer’s Disease Neuroimaging Initiative
PubMed: 22562439
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[Cerebrospinal fluid and plasma biomarkers for dementia with lewy bodies].

Brain Nerve. 2012 May;64(5):505-13
Authors: Kasuga K, Ikeuchi T
PubMed: 22570064
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[Biomarkers for Alzheimer's disease: after Alzheimer's disease neuroimaging initiative studies].

Brain Nerve. 2012 May;64(5):497-504
Authors: Shoji M
PubMed: 22570063
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[Biomarkers for amyotrophic lateral sclerosis].

Brain Nerve. 2012 May;64(5):515-23
Authors: Tokuda T
PubMed: 22570065
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Stromal cell-derived factor 1α decreases β-amyloid deposition in Alzheimer's disease mouse model.

Brain Res. 2012 Apr 17;
Authors: Wang Q, Xu Y, Chen JC, Qin YY, Liu M, Liu Y, Xie MJ, Yu ZY, Zhu Z, Wang W
PubMed: 22560596
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α-Synuclein mRNA and soluble α-synuclein protein levels in post-mortem brain from patients with Parkinson's disease, dementia with Lewy bodies, and Alzheimer's disease.

Brain Res. 2012 Apr 17;
Authors: Quinn JG, Coulson DT, Brockbank S, Beyer N, Ravid R, Hellemans J, Irvine GB, Johnston JA
PubMed: 22560502
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From α-synuclein to synaptic dysfunctions: New insights into the pathophysiology of Parkinson's disease.

Brain Res. 2012 Apr 17;
Authors: Bellucci A, Zaltieri M, Navarria L, Grigoletto J, Missale C, Spano P
PubMed: 22560500
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Elevated PGC-1α Activity Sustains Mitochondrial Biogenesis and Muscle Function without Extending Survival in a Mouse Model of Inherited ALS.

Cell Metab. 2012 May 2;15(5):778-86
Authors: Da Cruz S, Parone PA, Lopes VS, Lillo C, McAlonis-Downes M, Lee SK, Vetto AP, Petrosyan S, Marsala M, Murphy AN, Williams DS, Spiegelman BM, Cleveland DW
PubMed: 22560226
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Protective Effects of Pinostrobin on β-Amyloid-Induced Neurotoxicity in PC12 Cells.

Cell Mol Neurobiol. 2012 May 8;
Authors: Xian YF, Ip SP, Lin ZX, Mao QQ, Su ZR, Lai XP
PubMed: 22565301
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Clinical neuropathology practice news 3-2012: the.

Clin Neuropathol. 2012 May-Jun;31(3):116-8
Authors: Kovacs GG, Gelpi E
PubMed: 22551914
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Trafficking and Proteolytic Processing of APP.

Cold Spring Harb Perspect Med. 2012 May;2(5):a006270
Authors: Haass C, Kaether C, Thinakaran G, Sisodia S
PubMed: 22553493
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The clinical problem of symptomatic Alzheimer disease and mild cognitive impairment.

Cold Spring Harb Perspect Med. 2012 May;2(5):a006148
Authors: Tarawneh R, Holtzman DM
PubMed: 22553492
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Disruption of protein quality control in Parkinson's disease.

Cold Spring Harb Perspect Med. 2012 May;2(5):a009423
Authors: Cook C, Stetler C, Petrucelli L
PubMed: 22553500
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Pain medication and global cognitive functioning in dementia patients with painful conditions.

Drugs Aging. 2012 May 1;29(5):377-84
Authors: Plooij B, van der Spek K, Scherder EJ
PubMed: 22550967
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Estrogen-Induced Memory Enhancements Are Blocked by Acute Bisphenol A in Adult Female Rats: Role of Dendritic Spines.

Endocrinology. 2012 May 8;
Authors: Inagaki T, Frankfurt M, Luine V
PubMed: 22569790
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iTRAQ and multiple reaction monitoring as proteomic tools for biomarker search in cerebrospinal fluid of patients with Parkinson's disease dementia.

Exp Neurol. 2012 Apr;234(2):499-505
Authors: Lehnert S, Jesse S, Rist W, Steinacker P, Soininen H, Herukka SK, Tumani H, Lenter M, Oeckl P, Ferger B, Hengerer B, Otto M
PubMed: 22327139
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Ethical issues in Alzheimer's disease: an overview.

Expert Rev Neurother. 2012 May;12(5):557-67
Authors: Leuzy A, Gauthier S
PubMed: 22550984
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New and emerging treatments for Alzheimer's disease.

Expert Rev Neurother. 2012 May;12(5):535-43
Authors: Corbett A, Smith J, Ballard C
PubMed: 22550982
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Possible role of nicotine for the treatment of mild cognitive impairment.

Expert Rev Neurother. 2012 May;12(5):531-3
Authors: Roh S, Evins AE
PubMed: 22550981
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Loss of thioredoxin function in retinas of mice overexpressing amyloid β

Free Radic Biol Med. 2012 Apr 21;
Authors: Lamoke F, Ripandelli G, Webster S, Montemari A, Maraschi A, Martin P, Marcus DM, Liou GI, Bartoli M
PubMed: 22564527
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When Higher Activations Reflect Lower Deactivations: A PET Study in Alzheimer's Disease during Encoding and Retrieval in Episodic Memory.

Front Hum Neurosci. 2012;6:107
Authors: Bejanin A, Viard A, Chételat G, Clarys D, Bernard F, Pélerin A, De la Sayette V, Eustache F, Desgranges B
PubMed: 22557957
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Clinico-pathological correlations of the most common neurodegenerative dementias.

Front Neurol. 2012;3:68
Authors: Taipa R, Pinho J, Melo-Pires M
PubMed: 22557993
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Pathological alteration in the choroid plexus of Alzheimer's disease: implication for new therapy approaches.

Front Pharmacol. 2012;3:75
Authors: Krzyzanowska A, Carro E
PubMed: 22563316
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Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases?

Front Physiol. 2012;3:124
Authors: Bellingham SA, Guo BB, Coleman BM, Hill AF
PubMed: 22563321
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α-synuclein, LRRK2 and their interplay in Parkinson's disease.

Future Neurol. 2012 Mar;7(2):145-153
Authors: Liu G, Aliaga L, Cai H
PubMed: 22563296
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Gender, sex steroid hormones, and Alzheimer's disease.

Horm Behav. 2012 Apr 19;
Authors: Vest RS, Pike CJ
PubMed: 22554955
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Evidence for a Role of The Rare p.A152T Variant in MAPT in increasing the Risk for FTD-Spectrum and Alzheimer's Diseases.

Hum Mol Genet. 2012 May 3;
Authors: Coppola G, Chinnathambi S, Jiyong Lee J, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, Cotman CW, Decarli CS, Levey AI, Ringman JM, Mendez MF, Chui HC, Le Ber I, Brice A, Lupton MK, Preza E, Lovestone S, Powell J, Graff-Radford N, Petersen RC, Boeve BF, Lippa CF, Bigio EH, Mackenzie I, Finger E, Kertesz A, Caselli RJ, Gearing M, Juncos JL, Ghetti B, Spina S, Bordelon YM, Tourtellotte WW, Frosch MP, Vonsattel JP, Zarow C, Beach TG, Albin RL, Lieberman AP, Lee VM, Trojanowski JQ, Van Deerlin VM, Bird TD, Galasko DR, Masliah E, White CL, Troncoso JC, Hannequin D, Boxer AL, Geschwind MD, Kumar S, Mandelkow EM, Wszolek ZK, Uitti RJ, Dickson DW, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Alzheimer's Disease Genetics Consortium, Ross OA, Rademakers R, Schellenberg GD, Miller BL, Mandelkow E, Geschwind DH
PubMed: 22556362
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Dietary Cholesterol Concentration and Duration Degrade Long-Term Memory of Classical Conditioning of the Rabbit's Nictitating Membrane Response.

Int J Alzheimers Dis. 2012;2012:732634
Authors: Schreurs BG, Wang D, Smith-Bell CA, Burhans LB, Bell R, Gonzalez-Joekes J
PubMed: 22567532
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Endoplasmic reticulum: The unfolded protein response is tangled in neurodegeneration.

Int J Biochem Cell Biol. 2012 May 4;
Authors: Hoozemans JJ, Scheper W
PubMed: 22564438
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Personality traits and behavioral and psychological symptoms in patients at an early stage of Alzheimer's disease.

Int J Geriatr Psychiatry. 2012 May 2;
Authors: Pocnet C, Rossier J, Antonietti JP, von Gunten A
PubMed: 22552913
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Does the Addenbrooke's Cognitive Examination-revised add to the Mini-Mental State Examination in established Alzheimer disease? Results from a national dementia research register.

Int J Geriatr Psychiatry. 2012 May 4;
Authors: Law E, Connelly PJ, Randall E, McNeill C, Fox HC, Parra MA, Hudson J, Whyte LA, Johnstone J, Gray S, Starr JM
PubMed: 22556006
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Burden associated with the presence of anosognosia in Alzheimer's disease.

Int J Geriatr Psychiatry. 2012 May 4;
Authors: Turró-Garriga O, Garre-Olmo J, Vilalta-Franch J, Conde-Sala JL, de Gracia Blanco M, López-Pousa S
PubMed: 22555993
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The chalcone derivative Chana 1 protects against amyloid β peptide-induced oxidative stress and cognitive impairment.

Int J Mol Med. 2012 Jul;30(1):193-8
Authors: Kwak J, Kim MJ, Choi KC, Choi HK, Jun W, Park HJ, Lee YH, Yoon HG
PubMed: 22552354
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Hyperbaric oxygen and Ginkgo Biloba extract inhibit Aβ25-35-induced toxicity and oxidative stress in vivo: a potential role in Alzheimer's disease.

Int J Neurosci. 2012 May 8;
Authors: Qiang TX, Mei WJ, Guo DJ, Lin Y, Lida Z, Shan SS, Lin HP
PubMed: 22563944
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Delivery of Epidermal Neural Crest Stem Cells (EPI-NCSC) to hippocamp in Alzheimer's Disease Rat Model.

Iran Biomed J. 2012 Jan;16(1):1-9
Authors: Esmaeilzade B, Nobakht M, Joghataei MT, Rahbar Roshandel N, Rasouli H, Samadi Kuchaksaraei A, Hosseini SM, Najafzade N, Asalgoo S, Hejazian LB, Moghani Ghoroghi F
PubMed: 22562026
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Amyloid-β Secretion, Generation, and Lysosomal Sequestration in Response to Proteasome Inhibition: Involvement of Autophagy.

J Alzheimers Dis. 2012 May 3;
Authors: Agholme L, Hallbeck M, Benedikz E, Marcusson J, Kågedal K
PubMed: 22555375
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Upcoming meetings related to Alzheimer's disease.

J Alzheimers Dis. 2012 Jan 1;30(1):223-4
Authors: [No authors listed]
PubMed: 22561397
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Current Epidemiological Approaches to the Metabolic-Cognitive Syndrome.

J Alzheimers Dis. 2012 May 4;
Authors: Panza F, Solfrizzi V, Logroscino G, Maggi S, Santamato A, Seripa D, Pilotto A
PubMed: 22561330
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Cerebellar Amyloid-β Plaques: Disturbed Cortical Circuitry in AβPP/PS1 Transgenic Mice as a Model of Familial Alzheimer's Disease.

J Alzheimers Dis. 2012 May 4;
Authors: Lomoio S, López-González I, Aso E, Carmona M, Torrejón-Escribano B, Scherini E, Ferrer I
PubMed: 22561329
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Oxidative Stress and Memory Decline in Adults with Down Syndrome: Longitudinal Study.

J Alzheimers Dis. 2012 May 4;
Authors: Zis P, Dickinson M, Shende S, Walker Z, Strydom A
PubMed: 22561328
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Practical guidelines for the recognition and diagnosis of dementia.

J Am Board Fam Med. 2012 May;25(3):367-82
Authors: Galvin JE, Sadowsky CH
PubMed: 22570400
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Guidelines for the management of cognitive and behavioral problems in dementia.

J Am Board Fam Med. 2012 May;25(3):350-66
Authors: Sadowsky CH, Galvin JE
PubMed: 22570399
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Neuronal PAD4 expression and protein citrullination: Possible role in production of autoantibodies associated with neurodegenerative disease.

J Autoimmun. 2012 May 2;
Authors: Acharya NK, Nagele EP, Han M, Coretti NJ, Demarshall C, Kosciuk MC, Boulos PA, Nagele RG
PubMed: 22560840
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Proteomic analysis of wild-type and mutant huntingtin associated proteins in mouse brains identifies unique interactions and involvement in protein synthesis.

J Biol Chem. 2012 May 3;
Authors: Culver BP, Savas JN, Park SK, Choi JH, Zheng S, Zeitlin SO, Yates JR, Tanese N
PubMed: 22556411
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Exercise is more effective than diet control in preventing high fat diet-induced β-amyloid deposition and memory deficit in amyloid precursor protein transgenic mice.

J Biol Chem. 2012 May 4;
Authors: Maesako M, Uemura K, Kubota M, Kuzuya A, Sasaki K, Hayashida N, Asada-Utsugi M, Watanabe K, Uemura M, Kihara T, Takahashi R, Shimohama S, Kinoshita A
PubMed: 22563077
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Blood markers of oxidative stress in Alzheimer's disease.

J Cell Mol Med. 2012 May 5;
Authors: Skoumalová A, Hort J
PubMed: 22564475
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Blocking of bradykinin receptor B1 protects from focal closed head injury in mice by reducing axonal damage and astroglia activation.

J Cereb Blood Flow Metab. 2012 May 9;
Authors: Albert-Weissenberger C, Stetter C, Meuth SG, Göbel K, Bader M, Sirén AL, Kleinschnitz C
PubMed: 22569191
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Prion-like spread of protein aggregates in neurodegeneration.

J Exp Med. 2012 May 7;209(5):889-93
Authors: Polymenidou M, Cleveland DW
PubMed: 22566400
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Clinical Trials: New Opportunities.

J Gerontol A Biol Sci Med Sci. 2012 May 8;
Authors: Chapman SB, Cotman CW, Fillit HM, Gallagher M, van Dyck CH
PubMed: 22570132
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Neuroglial Expression of the MHCI Pathway and PirB Receptor Is Upregulated in the Hippocampus with Advanced Aging.

J Mol Neurosci. 2012 May 6;
Authors: Starkey HD, Van Kirk CA, Bixler GV, Imperio CG, Kale VP, Serfass JM, Farley JA, Yan H, Warrington JP, Han S, Mitschelen M, Sonntag WE, Freeman WM
PubMed: 22562814
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CSF markers in amyotrophic lateral sclerosis.

J Neural Transm. 2012 May 4;
Authors: Tarasiuk J, Kułakowska A, Drozdowski W, Kornhuber J, Lewczuk P
PubMed: 22555610
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Preventive immunization of aged and juvenile non-human primates to beta-amyloid.

J Neuroinflammation. 2012 May 3;9(1):84
Authors: Kofler J, Lopresti B, Janssen C, Trichel AM, Masliah E, Finn OJ, Salter RD, Murdoch GH, Mathis CA, Wiley CA
PubMed: 22554253
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Atrophy of medial temporal lobes on MRI in "probable" Alzheimer's disease and normal ageing: diagnostic value and neuropsychological correlates.

J Neurol Neurosurg Psychiatry. 2012 May 7;
Authors: Scheltens P, van der Pol L
PubMed: 22566596
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CREB-Dependent Transcriptional Control and Quantal Changes in Persistent Long-Term Potentiation in Hippocampal Interneurons.

J Neurosci. 2012 May 2;32(18):6335-50
Authors: Ran I, Laplante I, Lacaille JC
PubMed: 22553039
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Intensity and Interval Specific Repetitive Traumatic Brain Injury can Evoke both Axonal and Microvascular Damage.

J Neurotrauma. 2012 May 4;
Authors: Fujita M, Wei EP, Povlishock J
PubMed: 22559115
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Ghrelin and leptin secretion in patients with moderate Alzheimer's disease.

J Nutr Health Aging. 2012 May;16(5):472-7
Authors: Theodoropoulou A, Metallinos IC, Psyrogiannis A, Vagenakis GA, Kyriazopoulou V
PubMed: 22555794
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End-of-Life Care for Persons with Advanced Alzheimer Disease: Design and Baseline Data from the ALFINE Study.

J Nutr Health Aging. 2012 May;16(5):457-61
Authors: Nourhashémi F, Gillette S, Cantet C, Stilmunkes A, Saffon N, Rougé-Bugat ME, Vellas B, Rolland Y
PubMed: 22555791
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Nutritional Assessment and Follow-Up of Residents with and without Dementia in Nursing Homes in the Limousin Region of France: A Health Network Initiative.

J Nutr Health Aging. 2012 May;16(5):504-8
Authors: Jesus P, Desport JC, Massoulard A, Villemonteix C, Baptiste A, Gindre-Poulvelarie L, Lorgueuilleux S, Javerliat V, Fraysse JL, Preux PM
PubMed: 22555799
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Quality of life of persons with dementia.

J Nutr Health Aging. 2012 May;16(5):454-6
Authors: Keating N, Gaudet N
PubMed: 22555790
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Health implications of high dietary omega-6 polyunsaturated Fatty acids.

J Nutr Metab. 2012;2012:539426
Authors: Patterson E, Wall R, Fitzgerald GF, Ross RP, Stanton C
PubMed: 22570770
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New evidence on α-synuclein and Tau binding to conformation and sequence specific GC* rich DNA: Relevance to neurological disorders.

J Pharm Bioallied Sci. 2012 Apr;4(2):112-7
Authors: Vasudevaraju P, Guerrero E, Hegde ML, Collen TB, Britton GB, Rao KS
PubMed: 22557921
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CSF Aβ As An Effect Biomarker For Brain Aβ Lowering Verified by Quantitative Preclinical Analyses.

J Pharmacol Exp Ther. 2012 May 4;
Authors: Lu Y, Riddell D, Hajos-Korcsok E, Bales K, Wood KM, Nolan CE, Robshaw AE, Zhang L, Leung L, Becker SL, Tseng E, Barricklow J, Miller EH, Osgood S, O'Neill BT, Brodney MA, Johnson DS, Pettersson M
PubMed: 22562771
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Label-Free Quantitative LC-MS Proteomics of Alzheimer's Disease and Normally Aged Human Brains.

J Proteome Res. 2012 May 5;
Authors: Andreev VP, Petyuk V, Brewer H, Karpievitch YV, Xie F, Clarke J, Camp DG, Smith RD, Lieberman AP, Albin RL, Nawaz Z, Hokayem JE, Myers AJ
PubMed: 22559202
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Presymptomatic alterations in energy metabolism and oxidative stress in the APP23 mouse model of Alzheimer disease.

J Proteome Res. 2012 May 8;
Authors: Hartl D, Schuldt V, Forler S, Zabel C, Klose J, Rohe M
PubMed: 22568827
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Activity-dependent neuroprotector homeobox protein: A candidate protein identified in serum as diagnostic biomarker for Alzheimer's disease.

J Proteomics. 2012 Apr 21;
Authors: Yang MH, Yang YH, Lu CY, Jong SB, Chen LJ, Lin YF, Wu SJ, Chu PY, Chung TW, Tyan YC
PubMed: 22554909
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Copper dysfunction in Alzheimer's disease: From meta-analysis of biochemical studies to new insight into genetics.

J Trace Elem Med Biol. 2012 May 5;
Authors: Squitti R
PubMed: 22565015
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Update: A 60-year-old woman with mild memory impairment: review of mild cognitive impairment.

JAMA. 2012 May 2;307(17):1858
Authors: Libman H, Trivedi NS
PubMed: 22550200
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Phellodendron amurense and Its Major Alkaloid Compound, Berberine Ameliorates Scopolamine-Induced Neuronal Impairment and Memory Dysfunction in Rats.

Korean J Physiol Pharmacol. 2012 Apr;16(2):79-89
Authors: Lee B, Sur B, Shim I, Lee H, Hahm DH
PubMed: 22563252
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ARIA from off-key operas?

Lancet Neurol. 2012 Mar;11(3):207-8
Authors: Frisoni GB
PubMed: 22341028
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Olfactory identification testing as a predictor of the development of Alzheimer's dementia: A systematic review.

Laryngoscope. 2012 May 2;
Authors: Sun GH, Raji CA, Maceachern MP, Burke JF
PubMed: 22552846
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Steroidal alkaloids from Holarrhena antidysenterica as acetylcholinesterase inhibitors and the investigation for structure-activity relationships.

Life Sci. 2012 Apr 30;
Authors: Yang ZD, Duan DZ, Xue WW, Yao XJ, Li S
PubMed: 22569298
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Pathology supported genetic testing and treatment of cardiovascular disease in middle age for prevention of Alzheimer's disease.

Metab Brain Dis. 2012 Apr 19;
Authors: Kotze MJ, van Rensburg SJ
PubMed: 22552896
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Subclinical vascular disease and cerebral glutamate elevation in metabolic syndrome.

Metab Brain Dis. 2012 May 3;
Authors: Haley AP, Gonzales MM, Tarumi T, Tanaka H
PubMed: 22552897
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Using bacterial inclusion bodies to screen for amyloid aggregation inhibitors.

Microb Cell Fact. 2012 May 3;11(1):55
Authors: Villar-Piqué A, Espargaró A, Sabaté R, de Groot NS, Ventura S
PubMed: 22553999
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[Alzheimer's disease--treatment with and without drugs].

MMW Fortschr Med. 2012 Apr 19;154(7):85-7, 89-90
Authors: Wolter DK
PubMed: 22558882
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Adaptor Protein-2-mediated Endocytosis of the β-secretase BACE1 is Dispensable for Amyloid Precursor Protein Processing.

Mol Biol Cell. 2012 May 2;
Authors: Prabhu Y, Burgos PV, Schindler C, Farías GG, Magadán JG, Bonifacino JS
PubMed: 22553349
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Disruption of Nongenomic Testosterone Signaling in a Model of Spinal and Bulbar Muscular Atrophy.

Mol Endocrinol. 2012 May 8;
Authors: Schindler M, Fabre C, de Weille J, Carreau S, Mersel M, Bakalara N
PubMed: 22570336
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Inhibition of 6-hydroxydopamine-induced endoplasmic reticulum stress by sulforaphane through the activation of Nrf2 nuclear translocation.

Mol Med Report. 2012 Jul;6(1):215-9
Authors: Deng C, Tao R, Yu SZ, Jin H
PubMed: 22552270
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Mitochondrial Dysfunction-A Pharmacological Target in Alzheimer's Disease.

Mol Neurobiol. 2012 May 3;
Authors: Eckert GP, Renner K, Eckert SH, Eckmann J, Hagl S, Abdel-Kader RM, Kurz C, Leuner K, Muller WE
PubMed: 22552779
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The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2.

Nat Commun. 2012;3:814
Authors: López-Doménech G, Serrat R, Mirra S, D'Aniello S, Somorjai I, Abad A, Vitureira N, García-Arumí E, Alonso MT, Rodriguez-Prados M, Burgaya F, Andreu AL, García-Sancho J, Trullas R, Garcia-Fernàndez J, Soriano E
PubMed: 22569362
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Alzheimer disease: CSF biomarkers could be used in Aβ immunotherapy trials for AD.

Nat Rev Neurol. 2012 May 8;
Authors: Ozerlat I
PubMed: 22565210
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Alzheimer disease: Biomarker trajectories across stages of Alzheimer disease.

Nat Rev Neurol. 2012 May 8;
Authors: Frisoni GB
PubMed: 22565208
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Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease.

Neurobiol Aging. 2012 May 1;
Authors: Arnold SE, Louneva N, Cao K, Wang LS, Han LY, Wolk DA, Negash S, Leurgans SE, Schneider JA, Buchman AS, Wilson RS, Bennett DA
PubMed: 22554416
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Hippocampus neuronal metabolic gene expression outperforms whole tissue data in accurately predicting Alzheimer's disease progression.

Neurobiol Aging. 2012 May 3;
Authors: Stempler S, Waldman YY, Wolf L, Ruppin E
PubMed: 22560482
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'Limits and current knowledge of Pick's disease: its differential diagnosis' A translation of the 1957 Delay, Brion, Escourolle article.

Neurocase. 2012 May 4;
Authors: Thibodeau MP, Miller BL
PubMed: 22554132
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Kinin-mediated inflammation in neurodegenerative disorders.

Neurochem Int. 2012 Apr 23;
Authors: Guevara-Lora I
PubMed: 22554400
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The protective effects of tanshinone IIA on neurotoxicity induced by β-amyloid protein through calpain and the p35/Cdk5 pathway in primary cortical neurons.

Neurochem Int. 2012 Apr 25;
Authors: Shi LL, Yang WN, Chen XL, Zhang JS, Yang PB, Hu XD, Han H, Qian YH, Liu Y
PubMed: 22561406
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In vitro beneficial activation of microglial cells by mechanically-injured astrocytes enhances the synthesis and secretion of BDNF through p38MAPK.

Neurochem Int. 2012 Apr 25;
Authors: Yang H, Feng GD, Liang Z, Vitale A, Jiao XY, Ju G, You SW
PubMed: 22561407
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Short-term clinical outcomes for stages of NIA-AA preclinical Alzheimer disease.

Neurology. 2012 May 2;
Authors: Knopman DS, Jack CR, Wiste HJ, Weigand SD, Vemuri P, Lowe V, Kantarci K, Gunter JL, Senjem ML, Ivnik RJ, Roberts RO, Boeve BF, Petersen RC
PubMed: 22551733
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Nutrient intake and plasma β-amyloid.

Neurology. 2012 May 2;
Authors: Gu Y, Schupf N, Cosentino SA, Luchsinger JA, Scarmeas N
PubMed: 22551728
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Sleep Disturbances in Alzheimer's and Parkinson's Diseases.

Neuromolecular Med. 2012 May 3;
Authors: Rothman SM, Mattson MP
PubMed: 22552887
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Age-related changes in parahippocampal white matter integrity: A diffusion tensor imaging study.

Neuropsychologia. 2012 Apr 25;
Authors: Rogalski E, Stebbins GT, Barnes CA, Murphy CM, Stoub TR, George S, Ferrari C, Shah RC, Detoledo-Morrell L
PubMed: 22561887
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Protective effects of diazoxide against Aβ25-35-induced PC12 cell apoptosis due to prevention of endoplasmic reticulum stress.

Neuroreport. 2012 May 30;23(8):493-7
Authors: Kong M, Ba M
PubMed: 22551949
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Association between a variant of the sigma-1 receptor gene and Alzheimer's disease.

Neurosci Lett. 2012 Apr 25;
Authors: Fehér A, Juhász A, László A, Kálmán J, Pákáski M, Kálmán J, Janka Z
PubMed: 22561649
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The newly identified K(+) channel blocker talatisamine attenuates beta-amyloid oligomers induced neurotoxicity in cultured cortical neurons.

Neurosci Lett. 2012 May 4;
Authors: Wang Y, Song M, Hou L, Yu Z, Chen H
PubMed: 22561032
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Involvement of the Akt/GSK-3β/CRMP-2 pathway in axonal injury after hypoxic-ischemic brain damage in neonatal rat.

Neuroscience. 2012 Apr 30;
Authors: Xiong T, Tang J, Zhao J, Chen H, Zhao F, Li J, Qu Y, Ferriero D, Mu D
PubMed: 22554777
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Age-Dependent Neuroinflammatory Responses and Deficits in Long-Term Potentiation in the Hippocampus During Systemic Inflammation.

Neuroscience. 2012 Apr 30;
Authors: Liu X, Wu Z, Hayashi Y, Nakanishi H
PubMed: 22554776
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Intraspinal Stem Cell Transplantation in ALS: A Phase I Safety Trial, Technical Note & Lumbar Safety Outcomes.

Neurosurgery. 2012 May 4;
Authors: Riley J, Federici T, Polak M, Kelly C, Glass J, Raore B, Taub J, Kesner V, Feldman EL, Boulis NM
PubMed: 22565043
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Selenium induces cholinergic motor neuron degeneration in Caenorhabditis elegans.

Neurotoxicology. 2012 Apr 25;
Authors: Estevez AO, Mueller CL, Morgan KL, Szewczyk NJ, Teece L, Miranda-Vizuete A, Estevez M
PubMed: 22560997
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[Pharmacological profiles of galantamine: the involvement of muscarinic receptor].

Nihon Shinkei Seishin Yakurigaku Zasshi. 2012 Feb;32(1):1-8
Authors: Matsuda T, Ago Y, Takuma K
PubMed: 22568120
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Analysis of colonic alpha-synuclein pathology in multiple system atrophy.

Parkinsonism Relat Disord. 2012 May 2;
Authors: Pouclet H, Lebouvier T, Coron E, Rouaud T, Flamant M, Toulgoat F, Roy M, Vavasseur F, Bruley des Varannes S, Neunlist M, Derkinderen P
PubMed: 22560049
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Genetic inhibition of solute-linked carrier 39 family transporter 1 ameliorates aβ pathology in a Drosophila model of Alzheimer's disease.

PLoS Genet. 2012 Apr;8(4):e1002683
Authors: Lang M, Wang L, Fan Q, Xiao G, Wang X, Zhong Y, Zhou B
PubMed: 22570624
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MicroRNA-277 Modulates the Neurodegeneration Caused by Fragile X Premutation rCGG Repeats.

PLoS Genet. 2012 May;8(5):e1002681
Authors: Tan H, Poidevin M, Li H, Chen D, Jin P
PubMed: 22570635
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Human prion diseases in the Netherlands (1998-2009): clinical, genetic and molecular aspects.

PLoS One. 2012;7(4):e36333
Authors: Jansen C, Parchi P, Capellari S, Ibrahim-Verbaas CA, Schuur M, Strammiello R, Corrado P, Bishop MT, Van Gool WA, Verbeek MM, Baas F, van Saane W, Spliet WG, Jansen GH, van Duijn CM, Rozemuller AJ
PubMed: 22558438
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White Matter Differences between Healthy Young ApoE4 Carriers and Non-Carriers Identified with Tractography and Support Vector Machines.

PLoS One. 2012;7(4):e36024
Authors: O'Dwyer L, Lamberton F, Matura S, Scheibe M, Miller J, Rujescu D, Prvulovic D, Hampel H
PubMed: 22558310
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Amyloid-Beta (Aβ) D7H Mutation Increases Oligomeric Aβ42 and Alters Properties of Aβ-Zinc/Copper Assemblies.

PLoS One. 2012;7(4):e35807
Authors: Chen WT, Hong CJ, Lin YT, Chang WH, Huang HT, Liao JY, Chang YJ, Hsieh YF, Cheng CY, Liu HC, Chen YR, Cheng IH
PubMed: 22558227
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Electromagnetic Treatment to Old Alzheimer's Mice Reverses β-Amyloid Deposition, Modifies Cerebral Blood Flow, and Provides Selected Cognitive Benefit.

PLoS One. 2012;7(4):e35751
Authors: Arendash GW, Mori T, Dorsey M, Gonzalez R, Tajiri N, Borlongan C
PubMed: 22558216
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Tau-Mediated Nuclear Depletion and Cytoplasmic Accumulation of SFPQ in Alzheimer's and Pick's Disease.

PLoS One. 2012;7(4):e35678
Authors: Ke Y, Dramiga J, Schütz U, Kril JJ, Ittner LM, Schröder H, Götz J
PubMed: 22558197
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The influence of spin-labeled fluorene compounds on the assembly and toxicity of the aβ Peptide.

PLoS One. 2012;7(4):e35443
Authors: Petrlova J, Kálai T, Maezawa I, Altman R, Harishchandra G, Hong HS, Bricarello DA, Parikh AN, Lorigan GA, Jin LW, Hideg K, Voss JC
PubMed: 22558151
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Adult neurogenesis transiently generates oxidative stress.

PLoS One. 2012;7(4):e35264
Authors: Walton NM, Shin R, Tajinda K, Heusner CL, Kogan JH, Miyake S, Chen Q, Tamura K, Matsumoto M
PubMed: 22558133
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The contrasting effect of macromolecular crowding on amyloid fibril formation.

PLoS One. 2012;7(4):e36288
Authors: Ma Q, Fan JB, Zhou Z, Zhou BR, Meng SR, Hu JY, Chen J, Liang Y
PubMed: 22558423
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Early functional deficit and microglial disturbances in a mouse model of amyotrophic lateral sclerosis.

PLoS One. 2012;7(4):e36000
Authors: Gerber YN, Sabourin JC, Rabano M, Vivanco MD, Perrin FE
PubMed: 22558300
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Genetic Overexpression of NR2B Subunit Enhances Social Recognition Memory for Different Strains and Species.

PLoS One. 2012;7(4):e36387
Authors: Jacobs SA, Tsien JZ
PubMed: 22558458
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Role of alpha-synuclein protein levels in mitochondrial morphology and cell survival in cell lines.

PLoS One. 2012;7(4):e36377
Authors: Zhu M, Li W, Lu C
PubMed: 22558453
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Efficacy of memantine for agitation in Alzheimer's dementia: a randomised double-blind placebo controlled trial.

PLoS One. 2012;7(5):e35185
Authors: Fox C, Crugel M, Maidment I, Auestad BH, Coulton S, Treloar A, Ballard C, Boustani M, Katona C, Livingston G
PubMed: 22567095
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Abnormal Intracellular Accumulation and Extracellular Aβ Deposition in Idiopathic and Dup15q11.2-q13 Autism Spectrum Disorders.

PLoS One. 2012;7(5):e35414
Authors: Wegiel J, Frackowiak J, Mazur-Kolecka B, Schanen NC, Cook EH, Sigman M, Brown WT, Kuchna I, Wegiel J, Nowicki K, Imaki H, Ma SY, Chauhan A, Chauhan V, Miller DL, Mehta PD, Flory M, Cohen IL, London E, Reisberg B, de Leon MJ, Wisniewski T
PubMed: 22567102
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Concordant signaling pathways produced by pesticide exposure in mice correspond to pathways identified in human Parkinson's disease.

PLoS One. 2012;7(5):e36191
Authors: Gollamudi S, Johri A, Calingasan NY, Yang L, Elemento O, Beal MF
PubMed: 22563483
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TDP-43 Identified from a Genome Wide RNAi Screen for SOD1 Regulators.

PLoS One. 2012;7(4):e35818
Authors: Somalinga BR, Day CE, Wei S, Roth MG, Thomas PJ
PubMed: 22563406
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Striatal Dopamine Transmission Is Subtly Modified in Human A53Tα-Synuclein Overexpressing Mice.

PLoS One. 2012;7(5):e36397
Authors: Platt NJ, Gispert S, Auburger G, Cragg SJ
PubMed: 22570709
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Is tau ready for admission to the prion club?

Prion. 2012 Jul 1;6(3)
Authors: Hall GF, Patuto BA
PubMed: 22561167
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Genesis of tramsmissible protein states via deformed templating.

Prion. 2012 Jul 1;6(3)
Authors: Makarava N, Baskakov IV
PubMed: 22561163
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Calcium-based plasticity model explains sensitivity of synaptic changes to spike pattern, rate, and dendritic location.

Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3991-6
Authors: Graupner M, Brunel N
PubMed: 22357758
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Development of GABAergic inputs controls the contribution of maturing neurons to the adult hippocampal network.

Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4290-5
Authors: Li Y, Aimone JB, Xu X, Callaway EM, Gage FH
PubMed: 22371596
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Childhood maltreatment is associated with reduced volume in the hippocampal subfields CA3, dentate gyrus, and subiculum.

Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):E563-72
Authors: Teicher MH, Anderson CM, Polcari A
PubMed: 22331913
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Glucocorticoids interact with the hippocampal endocannabinoid system in impairing retrieval of contextual fear memory.

Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3504-9
Authors: Atsak P, Hauer D, Campolongo P, Schelling G, McGaugh JL, Roozendaal B
PubMed: 22331883
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Neuronal mRNAs travel singly into dendrites.

Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4645-50
Authors: Batish M, van den Bogaard P, Kramer FR, Tyagi S
PubMed: 22392993
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ApoE genotype: from geographic distribution to function and responsiveness to dietary factors.

Proc Nutr Soc. 2012 May 8;:1-15
Authors: Egert S, Rimbach G, Huebbe P
PubMed: 22564824
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Chronic traumatic encephalopathy: a review.

Rehabil Res Pract. 2012;2012:816069
Authors: Saulle M, Greenwald BD
PubMed: 22567320
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[For a new definition of the Alzheimer's disease.]

Rev Neurol (Paris). 2012 May 2;
Authors: Dubois B
PubMed: 22560011
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A review: inflammatory process in Alzheimer's disease, role of cytokines.

ScientificWorldJournal. 2012;2012:756357
Authors: Rubio-Perez JM, Morillas-Ruiz JM
PubMed: 22566778
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[How does glycosylation affect the metabolism of amyloid beta precursor protein?].

Seikagaku. 2012 Feb;84(2):111-5
Authors: Kitazume S
PubMed: 22550902
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[ER stress and neuropsychiatric disease].

Seishin Shinkeigaku Zasshi. 2012;114(2):115-23
Authors: Kudo T
PubMed: 22568114
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[Strategy and perspectives for development of Alzheimer disease-modifying drugs].

Seishin Shinkeigaku Zasshi. 2012;114(3):262-7
Authors: Yanagisawa K
PubMed: 22568060
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[The relationship between depression and dementia in elderly].

Seishin Shinkeigaku Zasshi. 2012;114(3):276-82
Authors: Fujise N, Ikeda M
PubMed: 22568062
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Soluble CCL5 Derived from Bone Marrow-Derived Mesenchymal Stem Cells and Activated by Amyloid-Beta Ameliorates Alzheimer's Disease in Mice by Recruiting Bone Marrow-Induced Microglia Immune Responses.

Stem Cells. 2012 May 8;
Authors: Lee JK, Schuchman EH, Jin HK, Bae JS
PubMed: 22570192
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[Diabetes mellitus and dementia].

Vnitr Lek. 2012 Apr;58(4):305-8
Authors: Tůma I
PubMed: 22559805
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