Alzforum - Papers of the Week: 11-17 Sep 2026

Systematic Dissection of Key Driver Perturbation Signatures in Single Cells via ECCITE-seq.

Methods Mol Biol. 2027;3074:193-208.
Authors: Zhang J, Brennand KJ, Zhang B, Wang M, Li A
PubMed: 42734752
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Physical exercise as a therapeutic strategy in animal models of Alzheimer's disease: Molecular, behavioral, and histopathological evidence.

Biochem Biophys Rep. 2026 Dec;48:102765. Epub 2026 Sep 4
Authors: Behrouzfar H, Gholami M, Hassani S, Maghsoudi AS, Bekheir SA
PubMed: 42733706
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Effective amyloid clearance with lecanemab in a female with Alzheimer's disease: A case report.

Radiol Case Rep. 2026 Dec;21(12):5973-5977. Epub 2026 Sep 7
Authors: Noguchi-Shinohara M, Ono K
PubMed: 42750750
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Research advances in the microbiota‑gut‑brain axis and Parkinson's disease (Review).

Mol Med Rep. 2026 Nov;34(5) Epub 2026 Sep 11
Authors: Meng Y, Liu Q, Zou H, Zhu X, Mi X, Li S, Xia Y, Ma Y, Yang Q, Peng J, Li J, Liu X, Chen J
PubMed: 42725392
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Advances in N- and S-Heterocycles as c-Jun-N-Terminal Kinase 3 Inhibitors for Alzheimer's Disease Treatment.

Drug Dev Res. 2026 Nov;87(7):e70381.
Authors: Yadav P, Mishra D, Singh R
PubMed: 42747078
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Mechanisms of NMDA receptor inhibition by fluoroethylnormemantine - comparison with memantine.

Eur J Pharmacol. 2026 Oct 28;1034:179334. Epub 2026 Sep 11
Authors: Furman VV, Zhigulin AS, Barygin OI
PubMed: 42727691
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Multi-functional bionic nanoparticles for precise neuronal targeting and synergistic therapy in Alzheimer's disease.

Mater Today Bio. 2026 Oct;40:103617. Epub 2026 Aug 28
Authors: Na Y, Liu C, Bi X, Liu S, Xing Y, Zhang B, Liu T, Zhang N, Geng F
PubMed: 42725138
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An Integrated Analysis of Manganese Metabolism-Related Genes and Their Association With Biomarkers, Immune Infiltration, and Clinical Subtypes in Alzheimer's Disease.

Genes Brain Behav. 2026 Oct;25(5):e70059.
Authors: Shu S, Hu J, Hu S, Yao Y
PubMed: 42723412
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Targeting TLR4/NF-κB/NLRP3 signaling with 6-hydroxyflavanone mitigates amyloid-β-induced Alzheimer's disease in mice.

Biomed Pharmacother. 2026 Oct;203:119833. Epub 2026 Sep 12
Authors: Rakshit D, Nema M, Mishra A
PubMed: 42731509
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Full-length brain-derived α-synuclein fibril models reveal fuzzy-coat control of peptide recognition.

Protein Sci. 2026 Oct;35(10):e70782.
Authors: Pintado-Grima C, Bárcenas O, Tesei G, Thomasen FE, Lindorff-Larsen K, Ventura S
PubMed: 42742050
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Function within disorder: Small heat shock proteins use different functional regions to chaperone tau aggregation.

Protein Sci. 2026 Oct;35(10):e70780.
Authors: Cervantes M, Janowska MK, Tuttle LM, Guttman M, Nath A, Klevit RE
PubMed: 42747073
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Thioperamide, a histamine H3 receptor antagonist, attenuates neuroimmune activation and inflammation in the SOD1G93A mouse model of amyotrophic lateral sclerosis.

Immunopharmacol Immunotoxicol. 2026 Sep 18;:1-12. Epub 2026 Sep 18
Authors: Aldossari AA, Alsaad AM, Nadeem A, Ansari MA, Attia SM, Bakheet SA, Al-Mazroua HA, Almutairi MM, Alhamami HN, Sarawi WS, Alomar HA, Algonaiah MA, Alshamrani AA, Alanteet AA, Hussein MH, Mahmoud MA, Ahmad SF
PubMed: 42745510
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Dynamic contributions of astrocytes in Alzheimer's disease.

Exp Neurol. 2026 Sep 18;407:116032. Epub 2026 Sep 18
Authors: Guo F, Li T, He XB
PubMed: 42753898
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Interpretable multimodal MRI fusion in Alzheimer's disease classification using extended parallel multilink joint ICA and 3D ResNet.

iScience. 2026 Sep 18;29(9):117313. Epub 2026 Sep 7
Authors: Lv C, Liu T, Chen H, Huang W, Huang M, Zang L, Shen C, Guo Y, Chen F
PubMed: 42750836
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A caution in interpreting reliable cognitive decline in older adults at risk for Alzheimer's disease.

Int Psychogeriatr. 2026 Sep 17;:100272. Epub 2026 Sep 17
Authors: Thomas ML
PubMed: 42754468
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Fault Lines in the Genome: Somatic DNA Mutations in Aging and Neurodegeneration.

Annu Rev Pathol. 2026 Sep 17; Epub 2026 Sep 17
Authors: Um J, Adelman JW, Pollina EA
PubMed: 42754244
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Deletion of NLRP3 gene blocks traumatic brain injury induced abnormal immune response in mice with a genetic background for AD.

Exp Neurol. 2026 Sep 17;:116030. Epub 2026 Sep 17
Authors: Green J, Liu Z, Timis S, Nelson C, Pedin A, Guo C, Wang XY, Zhang S, Sun D
PubMed: 42753897
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Word-Form and Lemma Dependency Networks of Connected Speech in Probable Alzheimer's Disease: Morphological Impacts on Syntactic Topological Metrics.

Semin Speech Lang. 2026 Sep 17; Epub 2026 Sep 17
Authors: Shi H
PubMed: 42753807
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Genomic and transcriptomic quality control for an autologous iPSC-derived cell therapy for Parkinson's disease.

Cell Stem Cell. 2026 Sep 17; Epub 2026 Sep 17
Authors: Bratt-Leal AM, Gorba T, Williams RM, Mossman JA, Hills R, Tran H, Barken D, Beauvais G, Fremgen D, Zhang A, Pivaroff C, Lynch C, Liu Y, Chandrasekaran C, Tastad D, Bridge C, Wakeman DR, Nguyen U, Chamberlain B, Lane EL, Lelos MJ, Loring JF, Wirth ED 3rd, Zhang X
PubMed: 42753738
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A clinically interpretable nomogram for predicting discharge outcomes in cerebral amyloid angiopathy-related lobar intracerebral hemorrhage: development and internal validation.

J Clin Neurosci. 2026 Sep 17;154:112293. Epub 2026 Sep 17
Authors: Zhang Y, Jia J, Wu X, Zhong Y, Huang X, Wang D, Ju Y
PubMed: 42753527
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40 Hz vibrotactile stimulation ameliorates amyloid pathology and cognitive deficits in 5xFAD mice and is associated with alterations in Piezo1, ERK, and GSK-3β/p65 signaling.

Neurotherapeutics. 2026 Sep 17;23(6):e01077. Epub 2026 Sep 17
Authors: Nam MH, Park HJ, Lee HY, Chen ZY, Yun HD, Kim Y, Lee JY, Shin CH, Ha JY, Seo YK
PubMed: 42753292
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Exosomes in Alzheimer's Disease: From Pathological Mechanisms to Biomarker Potential and Therapeutic Applications.

Mol Neurobiol. 2026 Sep 17;63(1)
Authors: Aydın AC
PubMed: 42753025
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A Lipoylation-PDH-TCA Transcriptional Deficit in the Alzheimer's Disease Cortex - Donor-level Multi-cohort Evidence with Neuronal-composition, Disease-specificity and Matched-null Controls.

J Mol Neurosci. 2026 Sep 17;76(4)
Authors: Zhang T, Chen X, Wang Y, Wang Y
PubMed: 42752765
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Amyloid-beta-targeting monoclonal antibodies in early Alzheimer's disease: a cochrane review summary and appraisal for the neurological community.

Neurol Sci. 2026 Sep 17;47(10)
Authors: Santos DH, da Silva AM
PubMed: 42752707
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A Molecularly Anchored Spatial Transcriptomic Framework for Precise CA1-Subiculum Parcellation and Region-Resolved Analysis in Alzheimer's Disease.

Gigascience. 2026 Sep 17; Epub 2026 Sep 17
Authors: Liu Y, He Y, Wei Y, Wang P, Huang C, Tao Q, Zhu L, Xu X, Liu L, Liu S, Han L, Zhang J, Wang L
PubMed: 42752570
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Evidence for multiple prion conformers in natural scrapie isolates.

PLoS Pathog. 2026 Sep 17;22(9):e1014283. Epub 2026 Sep 17
Authors: Imamura M, Miyazawa K, Okada H, Ohno M, Iguchi H, Matsuura Y, Iwamaru Y, Takatsuki H, Mori T, Ma J, Atarashi R
PubMed: 42752506
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Empathy on the edge: A neurocognitive model of empathy in aging and dementia.

Psychol Aging. 2026 Sep 17; Epub 2026 Sep 17
Authors: Abo Foul Y, Shamay-Tsoory S
PubMed: 42752160
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Chronic Hypertension and the Brain's Waste Drainage System.

Hypertension. 2026 Sep 17; Epub 2026 Sep 17
Authors: Alian M, Le C, Williams A, Wardlaw J, Benveniste H
PubMed: 42751772
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Cerebellar cortical amyloid deposition biases 18F-Florbetapir PET quantification with whole cerebellum as reference region.

Eur J Nucl Med Mol Imaging. 2026 Sep 17; Epub 2026 Sep 17
Authors: Wang M, Bi S, Xue H, Guan L, Wang Y, Zhang X, Liu X, Xu X, Zhang C, Qi Z, Zhao Z, Yan S, Lu J
PubMed: 42749937
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Erratum: Li et al., "Amelioration of Symptomatic Alzheimer's Disease after Selective Impairment of p75NTR Function in Adult Forebrain Excitatory Neurons".

J Neurosci. 2026 Sep 16;46(37)
Authors:
PubMed: 42728093
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The longevity gene APOE2 enhances pericyte function and reduces lipid droplets.

Brain. 2026 Sep 16; Epub 2026 Sep 16
Authors: Reskiawan A Kadir R, Bons J, Vega Hormazabal G, Vadhana Ashok Kumaar P, Gerónimo-Olvera C, Tshilenge KT, Pihán P, Galicia Aguirre C, Schneider K, Roberts A, Ambrose BD, Lerner C, Devanney NA, Sandholm AM, Hady M, Alderfer S, Hetz C, Furman D, Gerencser AA, Verdin E, Schilling B, Ellerby LM
PubMed: 42744302
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Corrigendum to "Ginsenoside Rg1 alleviates cognitive impairment in vascular dementia by modulating Adcy1/Kdr-mediated cholinergic synapse and PI3K-AKT pathway" [Phytomedicine, 143 (2025) 156882].

Phytomedicine. 2026 Sep 16;:158758. Epub 2026 Sep 16
Authors: Wang Y, Wei X, Wang H, Zhang Y, Li P, Zhou Y, Jiang S, Rong Y, Chen L, Zhao H
PubMed: 42749573
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Neuropsychiatric symptoms as predictors of progression to Alzheimer's disease in mild cognitive impairment: A comparative meta-analysis of apathy, depression, and anxiety.

Int Psychogeriatr. 2026 Sep 16;:100275. Epub 2026 Sep 16
Authors: Sun Y, Cao Y, Ma J, Li W, Li H, Tan Z
PubMed: 42749536
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Alzheimer's disease burden in China (ABC) study: protocol for a nationwide multicentre cross-sectional and prospective cohort study.

BMJ Open. 2026 Sep 16;16(9):e122035.
Authors: Wang Y, Qin Q, Yang K, Yu M, Yao Y, Gong C, Guo J, Yang L, Tang Y
PubMed: 42749375
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Inflection points and transitions in Alzheimer's disease.

Nature. 2026 Sep 16; Epub 2026 Sep 16
Authors: De Strooper B, Karran E
PubMed: 42749285
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From systems to cells: Metabolic mechanisms underlying risk divergence in Alzheimer's disease and amyotrophic lateral sclerosis.

Neurosci Biobehav Rev. 2026 Sep 16;191:106982. Epub 2026 Sep 16
Authors: Knezovic A, Krsnik A, Homolak J, Babic Perhoc A, Deskin A, Virag D, Salkovic-Petrisic M, Osmanovic Barilar J
PubMed: 42749235
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β-Amyloid and glutathione dysregulation cooperatively drive lipid peroxidation and ferroptosis in neuron-like cells.

Free Radic Biol Med. 2026 Sep 16;256:545-560. Epub 2026 Sep 16
Authors: Radeen KR, Hao C, Wei Z, Fan X
PubMed: 42749199
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Adaptive hypergraph learning reveals high-order functional network alterations in mild cognitive impairment.

Neuroscience. 2026 Sep 16; Epub 2026 Sep 16
Authors: Wu B, Jiang Z, Lv J, Zou L
PubMed: 42749078
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The double-edged sentinel: cGAS-STING as a context-dependent regulator of microglial senescence and neuronal genotoxic stress in neurodegeneration.

Brain Res Bull. 2026 Sep 16;245:112118. Epub 2026 Sep 16
Authors: Zhang C, Yang Z
PubMed: 42748981
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The Glymphatic System in Neurological Diseases: Mechanisms, Imaging Surrogates, and Translational Uncertainties.

Curr Neurol Neurosci Rep. 2026 Sep 16;26(1)
Authors: Raihane AS, Di Napoli M, Bragin D, Cáceres E, Ortiz MM, Moore MN, Divani AA
PubMed: 42747694
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TLR2 Regulates α-Synuclein Phosphorylation and Release in an Enteroendocrine Cell Model.

Mol Neurobiol. 2026 Sep 16;63(1)
Authors: Hu J, Elsaid S, Wu X, Ambye N, Tee SS
PubMed: 42747668
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Unraveling the regulatory nexus of aggrephagy in ALS: identification of novel candidate biomarkers and molecular triggers.

Metab Brain Dis. 2026 Sep 16;41(1)
Authors: Zhang Y, Wei K, Lin H, Guo Z, Lu Y, Ma T
PubMed: 42747562
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Alzheimer's Co-Pathology Burden on Basal Forebrain Atrophy and Cognitive Impairment in Dementia with Lewy Bodies: A Cross-Sectional Pilot Study.

Ann Neurol. 2026 Sep 16; Epub 2026 Sep 16
Authors: Urso D, Giannelli T, Tafuri B, Giannoni-Luza S, Gnoni V, Giugno A, Vilella D, Zecca C, De Blasi R, Nigro S, Aarsland D, Logroscino G
PubMed: 42747246
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Artificial Intelligence-Based Detection of ARIA on MRI During Alzheimer Disease Therapy: Expert Opinion on Responsible Clinical Integration.

AJR Am J Roentgenol. 2026 Sep 16; Epub 2026 Sep 16
Authors: Petrella JR, Barkhof F, Benzinger TL, Cogswell PM, Franceschi AM, Sabbagh MN, Salloway SP, Zaharchuk G, Doraiswamy PM
PubMed: 42747213
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Validation of plasma core biomarkers of Alzheimer's disease: A multicenter study in usual practice conditions.

J Alzheimers Dis. 2026 Sep 16;:13872877261487171. Epub 2026 Sep 16
Authors: Sánchez-Soblechero A, Villarejo A, Carreras MT, Berbel Á, Puertas C, Fernández-Bullido Y, Vieira A, Gundín I, Blanco-Palmero V, González-Sánchez M, Llamas S, Lapeña T, de Luis P, Lucio B, Ibáñez MD, Heredia P, Grandas F, Olazarán J
PubMed: 42746979
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L-serine-enriched diet restores impaired adult neurogenesis in the hippocampus of 3xTg-AD mice.

J Alzheimers Dis. 2026 Sep 16;:13872877261487394. Epub 2026 Sep 16
Authors: Than-Trong E, Torres L, Gaudin-Guérif M, Jan C, Ghettas A, Amadio A, Brainbank Neuro-CEB Neuropathology Network 5, Oliet SH, Panatier A, Bonvento G
PubMed: 42746964
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Recognition memory as a neuropsychological marker of progression in early-stage Alzheimer's disease: a 24-month prospective cohort study.

J Clin Exp Neuropsychol. 2026 Sep 16;:1-16. Epub 2026 Sep 16
Authors: Russo MJ, Bueri J, Alba-Ferrara L, Sevlever G, Allegri RF
PubMed: 42746710
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Sex-dependent Hippocampal Astrocytic Signaling and Synaptic Alterations Associated With Behavioral Impairments in Intracerebroventricular Streptozotocin-treated Rats.

Mol Neurobiol. 2026 Sep 16;63(1)
Authors: Hanotte JL, Peralta F, Escartin C, Carrillo-de Sauvage MÁ, Reggiani PC
PubMed: 42744995
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Deep Learning-Powered Plasmonic Platform for Decoding Dynamic Protein Aggregation Landscapes in Parkinson's Disease Progression.

Adv Mater. 2026 Sep 16;:e74985. Epub 2026 Sep 16
Authors: Zhou Y, Liu H, Yang X, Huang A, Li M, Dai Z, Liu S, Lu Y, Guo J, Liu S, Li C, Jiang C
PubMed: 42750405
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Temporal Trajectories of the Tau Aggregate Interactome Reveal Stage-Specific Vulnerabilities in Alzheimer's Disease.

Adv Sci (Weinh). 2026 Sep 16;:e77822. Epub 2026 Sep 16
Authors: Böken D, Lobo PB, Wu Y, Rowe LA, Fertan E, Croft CL, Jimenez-Sanchez M, Cox D, Klenerman D
PubMed: 42750204
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Alzheimer's Disease Beyond Amyloid: Lessons From Atherosclerosis.

Ann Clin Transl Neurol. 2026 Sep 16; Epub 2026 Sep 16
Authors: Ciaccio M, Agnello L
PubMed: 42750145
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Disrupted TFEB/GDNF-cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice.

Adv Sci (Weinh). 2026 Sep 16;:e22066. Epub 2026 Sep 16
Authors: Yao L, Hatami M, Koc S, Jiang Q, Skutella T, Zhang Y
PubMed: 42750142
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Brain region-resolved pharmacodynamics of an antisense oligonucleotide targeting human SNCA 3'UTR in BAC-hSNCA rats.

Transl Neurodegener. 2026 Sep 16;15(1)
Authors: Naki M, Kattan FG, Pantazopoulou M, Skea S, Zisis D, Pilalis E, Fouka M, Koronaiou E, Fotis C, Riess O, Chatziioannou A, Alexopoulos LG, Stefanis L, Doxakis E
PubMed: 42750047
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Quercetin-Based Nanotherapeutics for Targeted Drug Delivery in Alzheimer's Disease: Comparative Insights into Molecular Mechanisms, Blood-Brain Barrier Targeting and Therapeutic Perspectives.

Mol Neurobiol. 2026 Sep 16;63(1)
Authors: Begum MY, Rajkumar M, Govindaraj P, Velmani S, Rajkumar P, Sudha PN, Alhamod M, Alotaibi H
PubMed: 42749965
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Unconventional animal models of Alzheimer's disease and aging: key insights from the UAMAA 2026 conference.

Lab Anim (NY). 2026 Sep 16; Epub 2026 Sep 16
Authors: Garduño BM, Melgarejo T, Cogram P, Holmes TC, Xu X
PubMed: 42749851
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Targeting C/EBPβ/ Calbindin 1 pathway bolsters the neural resilience to tau pathology and improves tau-impaired episodic memory.

Mol Psychiatry. 2026 Sep 16; Epub 2026 Sep 16
Authors: Liu J, Zhang F, Zhong T, Wang J, Lei H, Zhao J, Lin F, Fan T, He T, Xiong R, Wang X, Wei L, Sun F, Xiao Y, Pi G, Kang D, Bian Y, Li H, Wang Q, Ke D, Wang JZ, Yang X, Wang ZH, Yang Y
PubMed: 42749775
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Map of brain 'microproteins' could offer new clues to Alzheimer's disease.

Nature. 2026 Sep 16; Epub 2026 Sep 16
Authors: Naddaf M
PubMed: 42749769
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The hnRNPA1 D262V amyotrophic lateral sclerosis (ALS) mutation is linked to mitochondrial dysfunction.

Genes Dev. 2026 Sep 15; Epub 2026 Sep 15
Authors: Lee YJ, Shen K, Dillin A, Rio DC
PubMed: 42744617
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Structural brain imaging for newly diagnosed cognitive impairment by Medicare coverage type.

J Am Coll Radiol. 2026 Sep 15; Epub 2026 Sep 15
Authors: Mattke S, Liu Y, Ye W, Altunkaynak K
PubMed: 42744196
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Alternative splicing in Alzheimer's disease: event-level evidence, risk-locus biology, and RNA-based therapeutic perspectives.

Gene. 2026 Sep 15;1013:150397. Epub 2026 Sep 15
Authors: Li J, Yue D, Xie W, Xiong Z, Wang X
PubMed: 42744164
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Amyloid-β aggregation inhibitory activity and neuroprotective effects of metabolites of Trichoderma pluripenicillatum.

Bioorg Med Chem Lett. 2026 Sep 15;142:130778. Epub 2026 Sep 15
Authors: Yoshikawa H, Matsumoto T, Yoshida E, Ohta T, Yoshida T, Noda Y, Shimohama S, Takata K
PubMed: 42744151
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Autopsy findings in Alzheimer's disease clinical trial participants demonstrate a high frequency of off-target coexisting pathologic features.

J Prev Alzheimers Dis. 2026 Sep 15;13(10):100669. Epub 2026 Sep 15
Authors: Coskun EP, Barber J, Bojarski L, McLouth CJ, Abner EL, Van Eldik LJ, Nelson PT, Jicha GA
PubMed: 42743907
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Dimethyl fumarate ameliorates amyloid-beta generated cognitive deficits by inhibiting RIPK1/RIPK3/MLKL necroptosis signalling in rats.

Int Immunopharmacol. 2026 Sep 15;189:117407. Epub 2026 Sep 15
Authors: Guin S, Jangli A, Dandekar MP
PubMed: 42743871
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Disease Course Map progression markers transfer from isolated REM sleep behavior disorder to non-RBD prodromal alpha-synucleinopathy: a PPMI study of 1,499 participants.

Parkinsonism Relat Disord. 2026 Sep 15;152:108985. Epub 2026 Sep 15
Authors: Fontana JC, Guimarães RL, de Faria AS, Braz KM, de Sá Pereira JF, Corrêa EM
PubMed: 42743773
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Corrigendum to "Real-world long-term continuation of lecanemab therapy and the clinical utility of phosphorylated tau 181" [The Journal of Prevention of Alzheimer's Disease (2026) 100664].

J Prev Alzheimers Dis. 2026 Sep 15;13(9):100668. Epub 2026 Sep 15
Authors: Noguchi-Shinohara M, Muramatsu D, Shima A, Sakashita Y, Tada Y, Yamaguchi H, Komatsu J, Ikeda T, Ono K
PubMed: 42743693
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From Proof of Principle to Therapeutic Discipline: Strategies to Improve the Benefit/Risk Profile of Amyloid-Targeting Treatments for Alzheimer's Disease.

CNS Drugs. 2026 Sep 15; Epub 2026 Sep 15
Authors: Perneczky R, Jessen F, Grimmer T, Levin J, Hufnagel A, Flöel A, Peters O, Froelich L, Hofmann A, Working Group New Therapies, Monitoring of the German Network Memory Clinics
PubMed: 42742914
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Pharmacological modulation of cGAS-STING-NLRP3 signaling by nano-immunomodulators in Alzheimer and Parkinson disease.

Inflammopharmacology. 2026 Sep 15; Epub 2026 Sep 15
Authors: Abdel-Rasol MA
PubMed: 42742907
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Peripheral TDP-43 pathology in amyotrophic lateral sclerosis: toward a systemic proteinopathy.

Acta Neuropathol. 2026 Sep 15;152(1)
Authors: Codron P, Miranda M, Garnier M, He S, Gouju J, Cassereau J, Leblanc P, Letournel F
PubMed: 42742812
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A new era of genome-wide association studies in the field of Alzheimer's disease and overlapping co-pathologies: lessons learned from a neuropathology-centered approach.

Acta Neuropathol. 2026 Sep 15;152(1)
Authors: Laureyssen C, Thal DR, Sleegers K
PubMed: 42742642
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Toward a Blood-Based Diagnosis of Progressive Supranuclear Palsy.

Mov Disord Clin Pract. 2026 Sep 15; Epub 2026 Sep 15
Authors: Barton N, Ghosh P, Kassavetis P
PubMed: 42742623
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Reply to: "Rare-Variant Burden in Mitochondrial Parkinson's Disease".

Mov Disord. 2026 Sep 15; Epub 2026 Sep 15
Authors: Percetti M, Yahya V, Di Fonzo A, Monfrini E
PubMed: 42742600
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A parsimonious three-gene mitochondrial classifier from frontal cortex for Alzheimer's disease: Nested cross-validation and multicenter external validation.

J Alzheimers Dis. 2026 Sep 15;:13872877261487424. Epub 2026 Sep 15
Authors: Wang M, Jing C, Wu T, Wang D
PubMed: 42742534
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Lower baseline cerebrospinal fluid amyloid-β 42 is associated with amyloid-related imaging abnormalities during real-world lecanemab treatment.

J Alzheimers Dis. 2026 Sep 15;:13872877261488874. Epub 2026 Sep 15
Authors: Takahashi R, Kashibayashi T, Fujita J, Yoshida K, Hashiramoto A, Kowa H, Mizuta E
PubMed: 42742530
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Associations of plasma lipid burden with cognitive performance and decline across dementia with Lewy bodies, Alzheimer's disease, and Parkinson's disease dementia.

J Alzheimers Dis. 2026 Sep 15;:13872877261487127. Epub 2026 Sep 15
Authors: Su Z, Liu M, Su L, Kuai J, Xu B, Wang C, Su M, Zheng Y, Peng J, Bao X, Zuo M, Guo X
PubMed: 42742528
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Altered neurovascular coupling in mild cognitive impairment and Alzheimer's disease: Associations with polysomnography-derived sleep parameters and cognition.

J Alzheimers Dis. 2026 Sep 15;:13872877261487585. Epub 2026 Sep 15
Authors: Xu Z, Bao L, Zhou S, Xue C, Peng L, Xiao C, Dong J
PubMed: 42742525
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APOE4 moderates the association of sleep disturbance with cerebral amyloid burden but not with clinical conversion in cognitively normal older adults.

J Alzheimers Dis. 2026 Sep 15;:13872877261487625. Epub 2026 Sep 15
Authors: Lee MJ, Kim JH, Choi HJ, Keum M, Byeon G, Ryu V, Suh GH, Kim JW, Choe YM, Alzheimer's Disease Neuroimaging Initiative
PubMed: 42742523
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Creutzfeldt-Jakob Disease in the Era of Diagnostic Triumph and Therapeutic Defeat: A Perspective from the Bedside.

Restor Neurol Neurosci. 2026 Sep 15;:9226028261488180. Epub 2026 Sep 15
Authors: Zhang X, Tian Y, Li C, Li M, Wang Z
PubMed: 42742480
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Rethinking the concept of disease modification in an evolving Parkinson's disease treatment landscape.

J Parkinsons Dis. 2026 Sep 15;:1877718X261481704. Epub 2026 Sep 15
Authors: Antonini A, Gross RE, De Leon M, Kwok K, Foltynie T, Höglinger G, Gasser T, Corvol JC, Pedrosa DJ, Volkmann J, Henchcliffe C
PubMed: 42742463
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ALS Research and Healey ALS MyMatch.

Ann Neurol. 2026 Sep 15; Epub 2026 Sep 15
Authors: Jacobson R, Babu S, Hurley J, Zawar I
PubMed: 42742283
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Social Media Claims About Blood Tests for Alzheimer's Disease and Dementia: A Cross-Sectional Content Analysis.

J Am Geriatr Soc. 2026 Sep 15; Epub 2026 Sep 15
Authors: Sujana RS, McCaffery KJ, Nickel B, Fox R, Naganathan V, Cumming RG, Smith J
PubMed: 42742271
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Resilience mechanisms in Parkinson's disease: a domain-specific conceptual framework.

Brain. 2026 Sep 15; Epub 2026 Sep 15
Authors: Ruppert-Junck MC, van Eimeren T, Giehl K, Helmich RC, Hönig M, Johansson ME, Mitterová K, Rektorová I, Waldthaler J, Pedrosa D, TRACE-PD consortium, the
PubMed: 42742269
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Structural abnormalities in gray matter, white matter, and cerebrospinal fluid in parkinson's disease: a voxel-based morphometry study.

Neurol Res. 2026 Sep 15;:1-14. Epub 2026 Sep 15
Authors: Shi Y, Zhang Y, Zhang Y, Wu Y, Liu X, Feng K, Cheng Y, Yin S
PubMed: 42742255
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UA-30 ameliorates motor deficits through RalA-mediated mitophagy in ALS mice.

J Clin Invest. 2026 Sep 15;136(18) Epub 2026 Sep 15
Authors: Zhang B, He Y, Su T, Li X, Zhang X, Liu R, Han X, Zhang R, Yang C, Liu X, Hou Q, Zhang Z, Xie Y, Liu G, Yang X
PubMed: 42741938
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Brain fluorodeoxyglucose PET anatomical segmentation via AI: extensive validation in the neurodegenerative spectrum.

Brain. 2026 Sep 15; Epub 2026 Sep 15
Authors: Silva LC, Oliveira FP, Costa DC, Alzheimer's Disease Neuroimaging Initiative and for the Frontotemporal Lobar Degeneration Neuroimaging Initiative
PubMed: 42740541
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The diagnostic biomarker problem in amyotrophic lateral sclerosis.

Brain. 2026 Sep 15; Epub 2026 Sep 15
Authors: Benatar M, Wuu J, Turner MR, Macklin EA
PubMed: 42736600
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Non-coding RNAs and Mitochondrial Dysfunction in Alzheimer's Disease: A Systematic Review.

Mol Neurobiol. 2026 Sep 15;63(1)
Authors: Mocrei-Rebrean ȘM, Răzniceanu V, Pintilie SR, Berindan-Neagoe I
PubMed: 42736501
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Conversion between the Brief assessment of Impaired Cognition, Brief Assessment of Impaired Cognition Questionnaire, and Mini-Mental State Examination in a mixed clinical sample.

Neurol Sci. 2026 Sep 15;47(10)
Authors: Jørgensen K, Nielsen TR, Kjaergaard D, Waldorff FB, Nielsen A, Nørgaard A, Salem LC, Langkilde TR, Waldemar G
PubMed: 42736410
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Characterising the motif composition and allele length distribution of ZFHX3 GGC repeat expansions in amyotrophic lateral sclerosis.

J Hum Genet. 2026 Sep 15; Epub 2026 Sep 15
Authors: Zussa ZN, Smith AN, van Vugt JJ, O'Shaughnessy DS, Grima N, Chan Moi Fat S, Blair IP, Rowe DB, Pamphlett R, Nicholson GA, Kiernan MC, van Rheenen W, Veldink J, Project MinE ALS sequencing consortium, Williams KL, Henden L
PubMed: 42736322
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Induction of ferroptotic and amyloidogenic signatures linked to Alzheimer's disease by chemically distinct air pollutants.

Redox Biol. 2026 Sep 15;97:104390. Epub 2026 Sep 15
Authors: Shkirkova K, Sta Maria NS, Anson H, Aghaei Y, Badami MM, Chakhoyan A, Godoy-Lugo JA, Chung C, Durra S, Tang-Tan A, Zhao L, Demetriou A, Morales M, Daggupati S, Bent I, Park H, Franklin C, Chen S, Chahine G, Dodds-Lewis S, Morishita M, Jacobs RE, Gout JF, Mack WJ, Forman HJ, Benayoun BA, Vermulst M, Cohen MD, Campen M, Sioutas C, Mack WJ, Finch CE, Thorwald MA
PubMed: 42748655
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Capillary blood sampling in neurodegenerative diseases - the future for screening and monitoring brain health?

Expert Rev Neurother. 2026 Sep 15;:1-6. Epub 2026 Sep 15
Authors: Hicks S, Fernandes Gomes B, Heslegrave A
PubMed: 42745552
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Investigating oral blarcamesine for treatment of early Alzheimer's disease.

Expert Opin Pharmacother. 2026 Sep 15; Epub 2026 Sep 15
Authors: Chandrasekaran A, Paget-Blanc A, Decourt B, Sabbagh MN
PubMed: 42745524
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Molecular Binding in Supramolecular Fibrillar Biomolecules.

Biophys J. 2026 Sep 15; Epub 2026 Sep 15
Authors: Umezaki U, Holladay C, Sonia He ZM, Chakraborty S, Martí AA
PubMed: 42745471
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Bioinformatics-driven discovery and cross-cohort validation of a two-gene signature (RPH3A and HIGD1B) associated with Alzheimer's disease.

Comput Biol Chem. 2026 Sep 15;126(Pt 1):109417. Epub 2026 Sep 15
Authors: Chen F
PubMed: 42753521
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Association of dietary choline intake with cognitive decline and related outcomes: a systematic review and dose-response meta-analysis of observational studies.

Food Funct. 2026 Sep 14; Epub 2026 Sep 14
Authors: Feng S, An K, Wang Y, Cheng Z, Ma X, Zhao X, Chen X, Qiao J
PubMed: 42735059
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Association between cerebrospinal fluid LRRK2 and incident orthostatic hypotension differs by genetic background in Parkinson's disease.

Acta Neurol Belg. 2026 Sep 14; Epub 2026 Sep 14
Authors: Kazemi E
PubMed: 42734894
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Optimization and characterization of lipid-based nanocarriers for intranasal delivery in amyotrophic lateral sclerosis.

Naunyn Schmiedebergs Arch Pharmacol. 2026 Sep 14; Epub 2026 Sep 14
Authors: P Padhiyar D, Butani S, Patel RJ
PubMed: 42734825
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Astrocytes in Neurodegeneration: Spatial States, Crosstalk, and Emerging Therapies.

Mol Neurobiol. 2026 Sep 14;63(1)
Authors: Steger L, Rothhammer V, Zunke F
PubMed: 42734724
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Autoimmune processes and production of catalytically active antibodies-abzymes in prone to amyotrophic lateral sclerosis FUS(1-359) mice.

Inflamm Res. 2026 Sep 14;75(1)
Authors: Urusov AE, Gorobets MA, Aulova KS, Timofeeva AM, Toporkova LB, Orlovskaya IA, Ustyugov AA, Nevinsky GA
PubMed: 42734657
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Correction to "Molecular Mechanism of Beta-Amyloid Aggregation Inhibition by KLVFF".

J Chem Inf Model. 2026 Sep 14;66(17):11542.
Authors: Cobos-Montes K, Fuentes SE, Estuardo F, Cárdenas C, Guzmán F, Santana P, Gavilán J, Figueroa M, Fuentealba J, Jiménez VA, Ramírez D
PubMed: 42734566
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Structural Hierarchy and Maturation of Amyloid Fibrils Revealed by Interface Descriptor Analysis.

J Chem Inf Model. 2026 Sep 14;66(17):11471-11490.
Authors: Sulyok-Eiler M, Harmat V, Perczel A
PubMed: 42734527
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Hyperactive KIF5A in Neurodegeneration.

Cytoskeleton (Hoboken). 2026 Sep 14;:e70204. Epub 2026 Sep 14
Authors: Villarroel-Campos D, Sleigh JN
PubMed: 42734068
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Medial Temporal Atrophy and Posterior Cingulate Structural Covariance in Mild Cognitive Impairment.

Int J Neurosci. 2026 Sep 14;:1-23. Epub 2026 Sep 14
Authors: Yang X, Lyu J, Wang J, Quan Y
PubMed: 42733346
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Circulating Metabolite Signatures Associated With Amyloid Positivity, Cognitive Performance and Plasma P-tau181 Levels in Cognitively Unimpaired Older Adults.

Mol Neurobiol. 2026 Sep 14;63(1)
Authors: Sharmin T, Doecke JD, Chatterjee P, Sohrabi HR, Zetterberg H, Ashton NJ, Garg ML, Blennow K, Martins RN
PubMed: 42733048
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Microglia Ablation and Downstream Effects in the Cerebrospinal Fluid Proteome.

Proteomics. 2026 Sep 14;:e70178. Epub 2026 Sep 14
Authors: Buchner S, Song S, Müller SA, Chen Y, Parhizkar S, Lichtenthaler SF, Holtzman DM, Jucker M, Kaeser SA
PubMed: 42740399
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Cerebral perfusion correlates of domain-specific cognitive function in Alzheimer's disease and dementia with Lewy bodies.

J Alzheimers Dis. 2026 Sep 14;:13872877261482134. Epub 2026 Sep 14
Authors: Koizumi Y, Nakano Y, Tamura M, Yamagishi K, Suzuki Y, Izumi M, Chishiki Y, Osawa K, Furukawa S, Ishikawa A, Kitayama Y, Horikoshi T, Uno T, Mori M, Kuwabara S, Hirano S
PubMed: 42736636
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APOE:RAAS epistasis as a population specific risk factor for cognitive impairment and cardiovascular health.

J Alzheimers Dis. 2026 Sep 14;:13872877261484965. Epub 2026 Sep 14
Authors: Tucker AE, Barber RC, Zhou Z, Jones HP, Phillips NR
PubMed: 42736635
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APOE-stratified genome-wide association analyses provide insights into the genetic etiology of Alzheimers's disease.

Nat Genet. 2026 Sep 14; Epub 2026 Sep 14
Authors: Thomassen JQ, Leonard H, Ulms B, Grenier-Boley B, Heikkinen S, Garcia-González P, Castillo-Morales A, Kikuchi M, Gim J, Cao H, Küçükali F, Amin N, Yoon D, de Rojas I, Alvarez Jerez P, Alvarez V, Arosio B, Bellenguez C, Bergh S, Billingsley K, Blauwendraat C, Boada M, Borroni B, Bossù P, Bullido MJ, Daniele A, Carracedo Á, de Mendonça A, Cookson M, Deckert J, Dichgans M, Djurovic S, Dols-Icardo O, Dufouil C, Düzel E, Escott-Price V, Fladby T, Fratiglioni L, Fu AK, Galimberti D, García-Alberca JM, Giedraitis V, Garcia-Ribas G, Graff C, Grimmer T, Grünblatt E, Hanon O, Hausner L, Heilmann-Heimbach S, Hort J, Jessen F, Jensen K, Jonson C, Kim Y, Kuznetsov N, Leinonen V, Lipponen A, Luo J, Makarious M, Martiskainen H, Masullo C, Mecocci P, Mehrabian S, Mir P, Miyashita A, Moebus S, Mok KY, Molina Porcel L, Moreno F, Nacmias B, Parnetti L, Pastor P, Pérez-Tur J, Peters O, Pijnenburg YA, Piñol-Ripoll G, Popp J, Rainero I, Real LM, Riedel-Heller S, Rodriguez-Rodriguez E, Rongve A, Rossi G, Royo JL, Rujescu D, Saltvedt I, Sáez ME, Sánchez-Valle R, Sanchez-Garcia F, Sandau N, Scarmeas N, Scheffler K, Scherbaum N, Schneider A, Selbæk G, Seripa D, Solfrizzi V, Spallazzi M, Squassina A, Stordal E, Tesi N, Tremolizzo L, Tripathi KP, van der Flier WM, Williams J, Wiltfang J, Aarsland D, Singleton AB, Amouyel P, Debette S, Tsolaki M, Nicolas G, van der Lee S, Holstege H, Fernandez MV, Kehoe PG, Sleegers K, Ingelsson M, Ghidoni R, Andreassen OA, Holmans PA, Sánchez-Juan P, Sims R, Ip NY, Lee KH, Ikeuchi T, Ramirez A, Ruiz A, Hiltunen M, Lambert JC, van Duijn C, Nalls M, Frikke-Schmidt R
PubMed: 42736378
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Triptolide preserves cognitive function and reduces hippocampal inflammation in a mouse model of Alzheimer's disease.

Mol Cell Neurosci. 2026 Sep 14;:104126. Epub 2026 Sep 14
Authors: Ma X, Li W, Ma Y, Ma W, Han Z
PubMed: 42735882
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Gut microbiota dysregulation in dementia: Molecular mechanism linking the gut-brain axis to neurodegeneration.

Ageing Res Rev. 2026 Sep 14;122:103373. Epub 2026 Sep 14
Authors: Bhamare JS, Jha P, Chintamaneni M, Kaur G
PubMed: 42735872
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Integrated proteomics and network pharmacology reveal autophagy-lysosomal regulation underlying sulforaphane-mediated neuroprotection in Alzheimer's disease.

Brain Res. 2026 Sep 14;1892:150549. Epub 2026 Sep 14
Authors: Li Y, Lu C, Liu N, Wang X, Li S
PubMed: 42735792
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DNA methylation changes associated with Parkinson's disease in SNCA.

Neuroscience. 2026 Sep 14; Epub 2026 Sep 14
Authors: Ntuli A, Jughoo C, Mpofana T, Lazarus L
PubMed: 42735781
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N-of-1 investigational study of a novel antisense oligonucleotide drug in CHCHD10-related ALS shows early signs of efficacy.

Med. 2026 Sep 14;:101295. Epub 2026 Sep 14
Authors: Cousin MA, Dagli AI, Mignon L, Shah JS, Prudencio M, Gendron TF, Jain A, Udine E, van Blitterswijk M, Middlebrooks EH, Donahue MH, Dagher JE, Watzlawik JO, Springer W, Parekh T, McEachin ZT, Petrucelli L, Oskarsson B
PubMed: 42735682
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Enhancing Alzheimer's disease diagnosis in primary care through targeted screening of people at risk of developing dementia - study design and feasibility assessment of the PREDEM primary care study.

Alzheimers Res Ther. 2026 Sep 14;18(1)
Authors: Aye S, Åhrberg S, Carlsson AC, Hasselström J, Alshamani I, Wallen S, van den Hurk W, Lund L, Jejcic A, Broome ST, Duran Sidera A, Tjernberg L, Jönsson L, Schedin-Weiss S
PubMed: 42745326
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Dysregulated TIE-2 expression in Alzheimer's disease: Further considerations on regional specificity and shedding evidence.

Brain Pathol. 2026 Sep 13;:e70151. Epub 2026 Sep 13
Authors: Zhang SQ, Liu M
PubMed: 42733001
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Hearing Loss Is Associated With Regional Brain Amyloid in a Late Middle-Aged Cohort.

Laryngoscope. 2026 Sep 13; Epub 2026 Sep 13
Authors: Powell SD, Weinstein HN, Aziz F, Brickman AM, Lao PJ, Eckert MA, Luchsinger JA, Golub JS
PubMed: 42732997
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Matrix metalloproteinase-9 is associated with CX3CL1 on tau and amyloid biomarker pathways in APOE4 carriers.

Neurobiol Dis. 2026 Sep 13;229:107605. Epub 2026 Sep 13
Authors: Johnson AK, Van Hulle CA, Zylstra H, Cronin K, Johnson K, Rivera-Rivera L, Chappell R, Wilson R, Kac PR, Gleason CE, Zetterberg H, Johnson SC, Auger AP, Carlsson CM
PubMed: 42732855
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Nrf2 overexpression ameliorates cognitive deficits and neuronal damage in APP/PS1 mice via attenuation of Aβ deposition and neuronal ferroptosis.

Neurosci Lett. 2026 Sep 13;887:138733. Epub 2026 Sep 13
Authors: Zhu X, Bo J, Qian Y, Diao F, Liang H, Fan L, Su Y, Li W
PubMed: 42732850
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Artificial Intelligence-Related Voice and Speech Biomarkers of Alzheimer's Disease: A Systematic Review.

J Voice. 2026 Sep 12; Epub 2026 Sep 12
Authors: Mairesse S, Briganti G, Lechien JR
PubMed: 42731970
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Clinical efficacy of non-pharmacological interventions on cognitive improvement in patients with mild to moderate Alzheimer's disease: A systematic review and Bayesian network meta-analysis.

J Alzheimers Dis. 2026 Sep 12;:13872877261485496. Epub 2026 Sep 12
Authors: Cui T, Han X, Yao Q, Xu C, Shan A, Wang X, Li S, Luan H, Wen B, Chen R, Guo J, Lian Q, Li C, Sun Y, Lv S, Wei C
PubMed: 42731086
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Exploring TIMP2 genetics and CSF levels in Parkinson's disease: biomarkers of neurodegeneration and ageing.

Geroscience. 2026 Sep 12; Epub 2026 Sep 12
Authors: Zimmermann M, Fandrich M, Schulte C, Jakobi M, Wurster I, Lerche S, Zimmermann S, Deuschle C, Schneiderhan-Marra N, Joos TO, Gasser T, Brockmann K, Roeben B
PubMed: 42730910
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Correction to: Resveratrol and neuroprotection: an insight into prospective therapeutic approaches against Alzheimer's disease from bench to bedside.

Mol Neurobiol. 2026 Sep 12;63(1)
Authors: Islam F, Nafady MH, Islam MR, Saha S, Rashid S, Akter A, Harun-Or-Rashid M, Akhtar MF, Perveen A, Ashraf GM, Rahman MH, Sweilam SH
PubMed: 42730894
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Dihydromyricetin ameliorates cognitive dysfunction in SAMP8 mice via autophagy-mediated degradation of the NLRP3 inflammasome.

Metab Brain Dis. 2026 Sep 12;41(1)
Authors: Liu XR, Zhang M, Chen DD, Chang JR, Kou XJ
PubMed: 42730882
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Genetics of α-Synuclein: The Prime Pathological Player of Parkinson's Disease.

Neurotox Res. 2026 Sep 12;44(5)
Authors: Sarhadi TR, Joshi N, Raveendran A, Panse JS, Nagotu S
PubMed: 42730873
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Progressive micrographia in Parkinson's disease is associated with multidimensional cognitive and motor features.

J Neural Transm (Vienna). 2026 Sep 12; Epub 2026 Sep 12
Authors: Hamada H, Mikami K, Itaguchi Y, Yoshida K, Yamashita A, An Q
PubMed: 42730821
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One-week changes on the Independent Living Scales in older adults: Proof of concept for quantifying subtle functional decline.

Clin Neuropsychol. 2026 Sep 12;:1-15. Epub 2026 Sep 12
Authors: Kannan L, Duff K
PubMed: 42730711
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Microbiome-gut-brain axis modulation for the management of Parkinson's disease: Emerging mechanisms and translational insights.

J Neuroimmunol. 2026 Sep 12;421:579099. Epub 2026 Sep 12
Authors: Porwal M, Malviya R, Chandra P, Sridhar SB, Shareef J, Wadhwa T, Tripathy DB, Arockiam D
PubMed: 42732715
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The method matters: free water imaging in Parkinson's disease is not a binary verdict.

NPJ Parkinsons Dis. 2026 Sep 12;12(1)
Authors: Martinez-Nunez AE, Barmpoutis A, Okun MS, Vaillancourt D
PubMed: 42731990
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Reply to 'The method matters: free water imaging in Parkinson's disease is not a binary verdict'.

NPJ Parkinsons Dis. 2026 Sep 12;12(1)
Authors: Roh YH, Youn J, Kim SY, Heo H, Song S, Sohn B
PubMed: 42731984
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[Effect of moxibustion-induced deqi on hippocampal autophagy function in APPswe/PSEN1dE9 transgenic Alzheimer's disease mice].

Zhongguo Zhen Jiu. 2026 Sep 12;46(9):1465-1472. Epub 2026 May 21
Authors: Lv Z, Xie D, Li H, Chen C, Chen R
PubMed: 42744633
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The role of gender in informant reports of cognitive decline in the United States and Mexico.

J Gerontol B Psychol Sci Soc Sci. 2026 Sep 12; Epub 2026 Sep 12
Authors: Cantu PA, Zhang Y, Saenz J, Wong R
PubMed: 42742165
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Disrupted interhemispheric communication in primary progressive aphasia: a multimodal MRI study of homotopic connectivity.

Neuroimage Clin. 2026 Sep 12;52:104061. Epub 2026 Sep 12
Authors: Tao Y, Tsapkini K, Rapp B
PubMed: 42753639
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Exploring the toxicological impact of BDE-209 on neurodegenerative diseases through network toxicology, molecular docking, molecular dynamics simulation and in-vitro study.

Toxicol Appl Pharmacol. 2026 Sep 11;516:118034. Epub 2026 Sep 11
Authors: Li X, Zhang S, Liu Y, Yu X, Han L, Liu Y
PubMed: 42727824
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Midbrain organoids as next-generation models for Parkinson's disease: From pathogenesis to therapeutic discovery.

Exp Neurol. 2026 Sep 11;407:116022. Epub 2026 Sep 11
Authors: Jiang DY, Yao SY, Du MQ, Lin LX, Kang XH, Peng Y
PubMed: 42727800
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ROS-xCT metabolic coupling defines an astrocyte subtype that drives glutamate excitotoxicity during Alzheimer's disease progression.

Life Sci. 2026 Sep 11;405:124679. Epub 2026 Sep 11
Authors: Xie X, Liu W, Chen L, Chen J, Jiang Y, Liu Q, Chen S
PubMed: 42727766
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Selective neuroprotection in the ALS-FTD spectrum: Mechanisms of neuronal resilience and translational perspectives.

Brain Res Bull. 2026 Sep 11;245:112111. Epub 2026 Sep 11
Authors: Inoue Y, Tanaka M, Oguchi T, Sasaki A, Saito K, Inoue A, Otsuka N
PubMed: 42727710
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Olfactory bulb-initiated α-synucleinopathy induces visual abnormalities via remote occipital network dysfunction.

Neurosci Res. 2026 Sep 11;:105118. Epub 2026 Sep 11
Authors: Amakusa Y, Takeuchi RF, Ito H, Iguchi Y, Ohba A, Kobayashi K, Yokoi S, Hamaguchi T, Hirunagi T, Sahashi K, Yamaguchi H, Osakada F, Katsuno M
PubMed: 42727708
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Predicting conversion from mild cognitive impairment to Alzheimer's disease: A systematic review of deep learning models for early-stage disease classification.

Ageing Res Rev. 2026 Sep 11;122:103372. Epub 2026 Sep 11
Authors: Ghasabi M, Aghdasi H, Feizi-Derakhshi MR
PubMed: 42727648
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Aerobic exercise and the gut-brain axis in Alzheimer's disease: Mechanistic perspectives, evidence appraisal, and future directions.

Ageing Res Rev. 2026 Sep 11;122:103347. Epub 2026 Sep 11
Authors: Wu J, Zhong Z, Sun Z, Yuan S, Qiu L
PubMed: 42727647
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Evidence for similar enzymatic but different cellular generation of pE79-modified α-synuclein in PD and AD mouse models.

Neurochem Int. 2026 Sep 11;200:106260. Epub 2026 Sep 11
Authors: Bluhm A, Großmann M, Minister C, Schrempel S, Joseph MA, Holzer M, Sauter C, Xiang W, Feja M, Schilling S, Schulze A, Richter F, Hartlage-Rübsamen M, Roßner S
PubMed: 42727643
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The path to treating multiple-etiology dementia: Combining vascular risk control and disease-modifying neurodegenerative therapies.

Neurotherapeutics. 2026 Sep 11;23(6):e01068. Epub 2026 Sep 11
Authors: de Havenon A, Sheth KN, Fredericks CA, Brickman AM
PubMed: 42727484
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Association of Herpes Simplex Virus Type-1 With Dementia Outcomes: Longitudinal Retrospective Cohort Study Using Real-World Electronic Health Record Data.

JMIR Form Res. 2026 Sep 11;10:e83028.
Authors: Islam MM, Foraker R, Hossain MS, Arnold WD, Dandachi D, Mosa AS
PubMed: 42727071
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Treating depression predicts cognitive improvement in Mild Cognitive Impairment: a 1-year prospective cohort study.

Aging Ment Health. 2026 Sep 11;:1-9. Epub 2026 Sep 11
Authors: Baldini V, Martinelli G, De Ronchi D, Macchiarulo M
PubMed: 42726936
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Limited Early-Life Sugar Intake Linked to Lower Dementia Risk.

JAMA. 2026 Sep 11; Epub 2026 Sep 11
Authors: Bock A
PubMed: 42726499
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Changes in sleep characteristics in Parkinson's disease: a prospective 5-year follow-up study.

J Clin Sleep Med. 2026 Sep 11;22(1)
Authors: Partinen E, Ylikoski A, Hublin C, Partinen M
PubMed: 42726411
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The Senescent Phenotype of Cultured Hypothalamic Astrocytes from Rats with Streptozotocin-Induced Dementia.

Neurochem Res. 2026 Sep 11;51(5)
Authors: Da Silva VF, da Costa DS, Gayger-Dias V, Sobottka TM, Da Silva AC, Biolchi BC, da Silva LF, Zasso N, Weber FB, Schimitz I, Machado DN, Netto CA, Leite MC, Bobermin LD, Quincozes-Santos A, Gonçalves CA
PubMed: 42726406
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Chronic kidney disease and cognitive decline: choroid plexus remodeling, glymphatic dysfunction, and alzheimer biomarker interpretation.

Neurol Sci. 2026 Sep 11;47(10)
Authors: Corrêa LM, Oliveira da Silva R, Brandão LK, Delmiro Silva YR, da Silva ÉV, Tretow J, Gomes ED, Fernandes CC, Moreira GN, Zanella J
PubMed: 42726307
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Molecular programs in human locus coeruleus link APOE and neuromelanin to Alzheimer's vulnerability.

Acta Neuropathol. 2026 Sep 11;152(1)
Authors: Mulvey B, Divecha HR, Tippani M, Bach SV, Bharadwaj R, Del Rosario I, Maguire SE, Miller RA, Salisbury AJ, Chandra A, Oster BA, Montgomery KD, Kwon SH, Algrain HA, Papariello AR, Huuki-Myers LA, Kleinman JE, Collado-Torres L, Hyde TM, Han S, Hicks SC, Weinberger DR, Page SC, Maynard KR, Martinowich K
PubMed: 42726290
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Circ_0004801 promotes tau hyperphosphorylation and cognitive impairment in Alzheimer's disease through the miR-7688-5p/TTBK1 axis.

J Alzheimers Dis. 2026 Sep 11;:13872877261487120. Epub 2026 Sep 11
Authors: Li Q, Xiao J, Deng G, Zhong H, Li Y, Lin W, Zhou M, Lu Y, Huang C, Wang C, Xuan A, Yang Q
PubMed: 42725992
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Cadmium exposure and incidence of all-cause dementia and Alzheimer's disease in US adults.

J Alzheimers Dis. 2026 Sep 11;:13872877261487104. Epub 2026 Sep 11
Authors: Walker E, Rodríguez-Carmona Y, Wang X, Mukherjee B, Arboleda-Merino L, Hao W, Dodge H, Albin RL, Paulson HL, Park SK, Bakulski KM
PubMed: 42725989
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Revisiting the role of amyloid-β: A molecular and immunological perspective.

J Alzheimers Dis. 2026 Sep 11;:13872877261484863. Epub 2026 Sep 11
Authors: Slama PS
PubMed: 42725888
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Implementation of a novel strategy to increase participation of Black and Hispanic people in parkinsonism research.

J Parkinsons Dis. 2026 Sep 11;:1877718X261487914. Epub 2026 Sep 11
Authors: Quintana Mora DF, McGoldrick AC, Mendez Y, Cervera A, Agarwal P, Crary JF, Walker RH, Nirenberg MJ
PubMed: 42725877
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Evaluation of the NIH Toolbox Odor Identification Test in African American older adults with and without amnestic mild cognitive impairment.

J Alzheimers Dis. 2026 Sep 11;:13872877261483176. Epub 2026 Sep 11
Authors: Ece B, Giordani B, Goldstein F, Weintraub S, Manly J, Dalton P, Parma V, Gershon RC, Ho EH
PubMed: 42725855
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Down Syndrome and Alzheimer's Disease: A Qualitative Study Exploring Understanding and Perceptions of Dementia and Diagnostic Pathways Among People With Down Syndrome and Their Families.

J Intellect Disabil Res. 2026 Sep 11; Epub 2026 Sep 11
Authors: Healy ML, Brodtmann A, Foster AM, Ayton D
PubMed: 42725843
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Cellular redox status is linked to olfactory alterations in cognitive decline.

Redox Biol. 2026 Sep 11;97:104393. Epub 2026 Sep 11
Authors: Lampinen R, Afonin AM, Mussalo L, Avesani S, Zavodna T, Feneberg E, Krejcik Z, Topinka J, Chew S, Löppönen H, Malm T, Giugno R, White AR, Koivisto AM, Penttilä E, Kanninen KM
PubMed: 42731289
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Research Trends and Mechanistic Insights Into Natural Medicines for Alzheimer's Disease: A Bibliometric Analysis and Narrative Review.

Phytother Res. 2026 Sep 11; Epub 2026 Sep 11
Authors: Wang M, Zhang X, Yang H, Zhao J, Wei W, Zhao Q, Wang W, Hu Y, Fang J
PubMed: 42730515
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Estrogen deprivation exacerbates Alzheimer's disease pathology through neuronal CTSS signaling.

J Neuroinflammation. 2026 Sep 11;23(1)
Authors: Yang R, Shao L, Huang F, He Y, Yuan M, Wu Q, Lin S, Guo K, Zhang H
PubMed: 42728627
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Joint impact of pathological burden and cognitive resilience on Alzheimer's disease risk.

Nat Med. 2026 Sep 11; Epub 2026 Sep 11
Authors: Wang Z, Wang S, Liang Y, Chen X, Wang S, Qin W, Wang Q, Li Y, Zhao T, Wang Y, Li F, Zhao G, Jia J
PubMed: 42728380
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Intentional Repetitive Slapping (IRS): A Novel Agitation Phenotype in Behavioral-Variant Frontotemporal Dementia.

Ann Indian Acad Neurol. 2026 Sep 11; Epub 2026 Sep 11
Authors: Thampi AS, Thampi AS, Xavier T, Mathew R
PubMed: 42734470
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Unraveling shared immunotoxicological mechanisms linking exposure to PPCPs with Alzheimer's disease and atherosclerosis: integrative multi-omics, network toxicology, and experimental validation.

Environ Int. 2026 Sep 11;216:110518. Epub 2026 Sep 11
Authors: Chen Z, Liu T, Wang J, Li P, Yuan H, Liu Z, Guo J
PubMed: 42743802
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Correlation between MMP-3-1171 5A/6A polymorphism and the risk of Alzheimer's disease: A meta-analysis.

Medicine (Baltimore). 2026 Sep 11;105(37):e50560.
Authors: Wang Y, Zhu S, Ma Y, Chen X, Zhou M
PubMed: 42742624
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Alzheimer's prevention drug trial: is a "statin for the brain" on the horizon?

BMJ. 2026 Sep 10;394:e100822.
Authors: Wise J
PubMed: 42727955
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EXPRESS: Rapamycin increases cerebral blood flow and modulates metabolic, inflammatory, and microbiome profiles in healthy middle-aged APOE4 carriers: a pilot single-arm trial.

J Cereb Blood Flow Metab. 2026 Sep 10;:271678X261490342. Epub 2026 Sep 10
Authors: Aware C, Neher CM, Woods C, Khegai O, Dwivedi AK, Govindarajan M, Ivanich K, Kurt M, Beversdorf D, Cheng J, Bresette N, Cui T, Balchandani P, Gonzales MM, Ericsson AC, Altes T, Lin AL
PubMed: 42723264
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Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy-Related Inflammation.

Ann Clin Transl Neurol. 2026 Sep 10; Epub 2026 Sep 10
Authors: Kharal GA, Yerneni G, Griffin KJ, Thompson N, Uchino K, Katzan I, Wisco D, Farrag A, Sundarajan J, Russman A, Hussain MS
PubMed: 42723177
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Retromer-targeted therapy for neurodegenerative diseases.

Mol Neurodegener. 2026 Sep 10;21(1)
Authors: Persico M, Tuithung S, Lorenzo A, Crawford D, Eleuteri S, Simon DK
PubMed: 42723096
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Emotional brain responses and pattern expressions in right temporal variant frontotemporal dementia.

J Neurol. 2026 Sep 10;273(10)
Authors: Adams J, Gundem D, Yargholi E, Luo Q, Sunaert S, Peeters R, De Winter FL, D Wager T, Vandenbulcke M, Van den Stock J
PubMed: 42722905
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AI-guided discovery of a brain-penetrant LILRB4 inhibitor active in microglial and 5xFAD models of Alzheimer's disease.

Bioorg Chem. 2026 Sep 10;182:110508. Epub 2026 Sep 10
Authors: Abdel-Rahman SA, Gabr MT
PubMed: 42731186
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Crystal Structure of the Sigma‑2 Receptor Complexed with Investigational Drug Zervimesine (CT1812).

ACS Med Chem Lett. 2026 Sep 10;17(9):1925-1932. Epub 2026 Aug 7
Authors: Look GC, Gilzer D, Preuss F, Wollenhaupt J, Nitsche J, Amaudrut J, Malancona S, Montalbetti CA, Caggiano AO, Hamby ME
PubMed: 42741631
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Differential aggregation and seeding of tau microtubule-binding region fragments in vitro.

Biochem Biophys Res Commun. 2026 Sep 9;836:154575. Epub 2026 Sep 9
Authors: Kim MS, Hwang SJ, Kim DH, Yoon SY
PubMed: 42727478
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Retinal and Choroidal Structure and Microvasculature in Dementia With Lewy Bodies and Alzheimer Disease.

J Vitreoretin Dis. 2026 Sep 9;:24741264261479309. Epub 2026 Sep 9
Authors: Zhu M, Dasgupta A, Jotsinghani D, Hsu J, D'Cunha R, Choi A, Haystead A, Stinnett SS, Johnson KG, Grewal DS, Fekrat S
PubMed: 42723990
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Emerging therapies expected to make a difference in Parkinson's disease management.

Parkinsonism Relat Disord. 2026 Sep 9;:108962. Epub 2026 Sep 9
Authors: An AY, Kalia LV
PubMed: 42744685
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Beyond the Single-Target Approach: Polypharmacology and Multi-Target Therapeutics in Alzheimer's Disease.

Cent Nerv Syst Agents Med Chem. 2026 Sep 9; Epub 2026 Sep 9
Authors: Yadav R, Sinha J, Deeksha K
PubMed: 42736653
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Novel Amyloid-β Aggregation Inhibitors Based on Phenylalanine Structure.

Curr Alzheimer Res. 2026 Sep 7; Epub 2026 Sep 7
Authors: Xu M, Wang H, Li S, Ye J, Sun Y, Xu Y, Zhang H, Zhao W, Zhang J
PubMed: 42725603
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The Gut-Brain Axis: Exploring the Role of Gut Microbiota in Alzheimer's Disease Pathogenesis and Therapeutics.

CNS Neurol Disord Drug Targets. 2026 Sep 7; Epub 2026 Sep 7
Authors: Fatima J, Siddique YH
PubMed: 42725602
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Altered neuronal start codon stringency favors cap-independent repeat-associated non-AUG translation.

Nucleic Acids Res. 2026 Sep 7;54(17)
Authors: Wieland CM, Wright SE, Willey S, Purwar I, Grudzien SJ, Krans A, Laimon EL, Asher MJ, Isaacs AM, Garner AL, Todd PK
PubMed: 42725432
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Cognitive and Behavioural Profile of SOD1-ALS Across the ALS-FTD Spectrum: A Systematic Review.

Int J Mol Sci. 2026 Sep 7;27(17)
Authors: Ginanni F, Nicoletti F, Meoni C, Becattini L, Mancuso M, Carlesi C, Bianchi F
PubMed: 42737854
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Quantitative Analysis of Axonal Degeneration and TDP-43 Aggregation in Compartmentalized Human iPSC-Derived Motor Neuron-Myotube Co-cultures.

Bio Protoc. 2026 Sep 5;16(17):e5801. Epub 2026 Sep 5
Authors: Subramaniam AG, de Andrade Gensas LK, Gradus-Pery T, Perlson E
PubMed: 42729071
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Presymptomatic Amyotrophic Lateral Sclerosis: From Early Biomarker Detection to Phenoconversion Prediction.

Diagnostics (Basel). 2026 Sep 5;16(17)
Authors: Chen M, Li H, Jin Q
PubMed: 42739287
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Hydroxytyrosol as a Multitarget Neuroprotective Agent: Molecular Mechanisms, Pharmacokinetics and Therapeutic Potential in Neurodegenerative Diseases.

Molecules. 2026 Sep 5;31(17)
Authors: Ballester-Navarro P, García-Muñoz AM, Victoria-Montesinos D, Zafrilla P
PubMed: 42738773
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Altered Epoxyeicosatrienoic Acid Signaling in Advanced-Stage Alzheimer's Disease (Investigation of Epoxyeicosatrienoic Acid Levels in Patients with Advanced Alzheimer's Disease).

Curr Alzheimer Res. 2026 Sep 4; Epub 2026 Sep 4
Authors: Erşan S, Özmen E, Sari İ, Erşan EE
PubMed: 42725525
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Circadian Rhythm Disruption in Alzheimer's Disease: Mechanistic Insights, Diagnostic Implications, and Emerging Chronotherapeutic Strategies: A Narrative Review.

CNS Neurol Disord Drug Targets. 2026 Sep 4; Epub 2026 Sep 4
Authors: Kaur J, Kainth R, Mittal R, Kaur A, Kushwah AS
PubMed: 42725517
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Cardiometabolic medication exposures and cognitive outcomes in Alzheimer's disease.

Age Ageing. 2026 Sep 4;55(9)
Authors: Wang Y, Goudey B, Masters CL, Jin L, Pan Y, Health and Aging Brain Study (HABS-HD) Study Team
PubMed: 42735389
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Effects and mechanisms of Stauntonia brachyanthera Hand.-Mazz against Alzheimer's disease through network pharmacology and experimental validation.

Biochem Biophys Res Commun. 2026 Sep 3;836:154546. Epub 2026 Sep 3
Authors: Wang J, Pu H, Peng L, Cai S, Ding Q, Chen X, Liu Y, Xiong W, Liao Y, Tang G
PubMed: 42727480
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Artemisinin Activates AMPK to Rescue Neuronal Cells and 3xTg Mice from Aβ1-42 Neurotoxicity.

Curr Neuropharmacol. 2026 Sep 3; Epub 2026 Sep 3
Authors: Chen Y, Xiong W, Ge L, Zheng W
PubMed: 42725510
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Alzheimer's Disease in the Era of Geroscience: Mechanisms, Biomarkers, and Therapeutic Prospects.

Cells. 2026 Sep 2;15(17)
Authors: Chmielewski PP
PubMed: 42738893
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Efficacy of Low Dose of Dihydroquercetin (DHQ) in Two Genetic Models of Neurodegeneration: Insights from FUS[1-359]-Tg and APPswe/PS1dE9 Paradigms.

Cells. 2026 Sep 2;15(17)
Authors: Lysikova E, Sitdikova K, Makhambetova A, Chaprov K, Gorlova A, Kostin A, Novikova P, Lyundup A, Askarova S, Kukharsky MS, Deykin A, Strekalova T
PubMed: 42738892
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The Paradox of Tau and RNA-Binding Proteins: How Adaptive Stress Granule Regulation Becomes Pathological with Aging.

Cells. 2026 Sep 2;15(17)
Authors: Wolozin B, Best M, Ellini M, Ma Y, Bok S, Hwang D, Filipponi C
PubMed: 42738890
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Modeling Tau-Mediated Pathology in Monkey Brain Slices.

Biology (Basel). 2026 Sep 2;15(17)
Authors: Pan M, Guo Q, Huang P, Han X, Yang S, Sun F, Zhang J, Chen L, Li B, He D, Li S, Li XJ, Guo X
PubMed: 42737927
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Older adult APOE4 mice exhibit modest immunometabolic adaptation following microglial APOE2 replacement.

Neurobiol Aging. 2026 Sep 2;169:13-26. Epub 2026 Sep 2
Authors: Nolt GL, MacLean SM, Golden LR, Thorpe SP, Stephens IO, Funnell JL, Brock CR, Lucido CC, Smith L, Hernandez G, Arbones-Mainar JM, Wood C, Morganti JM, Johnson LA
PubMed: 42748650
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[Alzheimer's disease: scientific advances, diagnostic challenges and therapeutic perspectives].

Soins. 2026 Sep;71(908):14-19. Epub 2026 Aug 27
Authors: Chenault C, Tchalla A
PubMed: 42727999
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[4-Repeat Tauopathies: Progressive Supranuclear Palsy and Corticobasal Degeneration].

Fortschr Neurol Psychiatr. 2026 Sep;94(9):389-399. Epub 2026 Sep 11
Authors: Palleis CT, Bernhardt A, Höglinger G
PubMed: 42727959
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ENT1 inhibition links oligodendrocyte lipid metabolism to connectivity in tauopathy.

Alzheimers Dement. 2026 Sep;22(9):e71789.
Authors: Chang CP, Chang CW, Wu CW, Siew JJ, Blum D, Jin LW, Chen YY, Chern Y
PubMed: 42725558
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Microvascular damage in diabetic nephropathy and the subsequent risk of Alzheimer's disease: a systematic review.

Ann Med Surg (Lond). 2026 Sep;88(9):5922-5929. Epub 2026 Aug 21
Authors: Mohammed N, Alyazan Khalil Taher Al-Jabali T, Yassien N, Osman Abufatima I, Omer Ibrahim Ahmed F, El Yazal S, Satti W, Alalamat N, Aamer Abkar Ibrahim M, Tirelbar B, Paudel L, Abdalla Abdelsadig Mahmoud I, Humdi L, Ali H, Hammad Jaber Amin M, Abdelrahman N
PubMed: 42724815
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Advances in Targeting Central Cholinergic Dysfunction for Neurodegenerative Diseases: From Pharmacotherapy to Neuromodulation.

CNS Neurosci Ther. 2026 Sep;32(9):e71151.
Authors: Lei L, Hu X, Lu R, Yang JJ, Meng Q
PubMed: 42723527
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Assessing the Clinical Relevance of Blood Soluble Triggering Receptor Expressed on Myeloid Cells 2 in Neurological Diseases.

Eur J Neurosci. 2026 Sep;64(5):e70690.
Authors: Agnello L, Gambino CM, Salemi G, Di Stefano V, Piccoli T, Masucci A, Novara S, Ciaccio AM, Del Ben F, Capello D, Ciaccio M
PubMed: 42723297
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Rethinking Senescence Hallmarks in the Brain: Lessons From Peripheral Tissues and Challenges in Defining Neuronal Senescence.

Aging Cell. 2026 Sep;25(9):e70719.
Authors: Momand MU, Macova K, Fricova D
PubMed: 42730505
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Recent Advancements in Drug Delivery Across the Blood-Brain Barrier in Amyotrophic Lateral Sclerosis (ALS).

CNS Neurosci Ther. 2026 Sep;32(9):e71078.
Authors: Sanghai N, Pierce K, Sharma N, Leggett S, Yadav TC, Masrori P, Atukorallaya D, Palaniyandi S, Marcogliese PC, Tranmer GK
PubMed: 42728797
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Integrative analysis of single-cell multi-omics reveals heterogeneity in piriform cortex principal neurons and their selective vulnerability in Alzheimer's disease.

Clin Transl Med. 2026 Sep;16(9):e70781.
Authors: Meng J, Zhang M, Chen Y, Han M, Cheng N, Cao R, He Q, Zhao Y, Yuan L, Zhang G
PubMed: 42728785
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SynthPET: A 3D generative AI approach for FDG-PET image synthesis from T1-weighted MRI and ASL CBF in Alzheimer's disease.

Alzheimers Dement. 2026 Sep;22(9):e71822.
Authors: Beltran-Urbano X, Jobson KR, Nasrallah IM, Kumar A, Taso M, Das SR, Brown CA, Li S, Xie L, McMillan CT, Yushkevich PA, Wolk DA, Zaharchuk G, Dolui S, Detre JA, Alzheimer's Disease Neuroimaging Initiative
PubMed: 42728741
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Cellular transcriptomic signatures underpinning the heterogeneity of depression in Alzheimer's disease.

Alzheimers Dement. 2026 Sep;22(9):e71823.
Authors: Lutz MW, Man Z, Chiba-Falek O
PubMed: 42728740
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Fibronectin mediates APOE4-driven blood-brain barrier dysfunction in Alzheimer's disease.

Nat Aging. 2026 Sep;6(9):1901-1927. Epub 2026 Sep 11
Authors: Bhattarai P, Yilmaz E, Cakir EÖ, Tayran H, Haq I, Murphy D, Keller JN, Le Grand Q, Eschbach JO, Celikkaya H, Cosacak MI, Yüceer Korkmaz H, Lee AJ, Haage V, Ma Y, Wang X, Nelson N, Lin W, Zhang Y, Turgutalp B, de Leeuw SM, Patel R, Jülich D, İş Ö, Holley SA, De Jager PL, Freudenberg U, Werner C, St George-Hyslop P, Ertekin-Taner N, Debette S, Elahi FM, Fisher ES, Phatnani H, Teich AF, Tubbesing K, Bertucci T, Temple S, Nuriel T, Vardarajan BN, Mayeux R, Kizil C
PubMed: 42728404
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Associations between serum estradiol and estrone and Alzheimer's disease biomarkers: An analysis in female participants from the European Prevention of Alzheimer's Dementia Longitudinal Cohort Study (EPAD LCS).

Alzheimers Dement. 2026 Sep;22(9):e71826.
Authors: Shin J, Muniz-Terrera G, Ritchie CW, Manson J, Plachecki S, Kirschbaum C, Gregory S
PubMed: 42733033
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Machine Learning for Noninvasive Diagnosis of Neurodegenerative Diseases Using Retinal and Optic Nerve Imaging: A Comprehensive Review.

Annu Rev Vis Sci. 2026 Sep;12(1):155-186.
Authors: Aghababaei A, Etemadifar M, Atapour-Abarghouei A, Innes W, Fard MA, Paul F, Rabbani H, Kafieh R
PubMed: 42744757
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Reliable detection and continuous monitoring of memory dysfunction in mild cognitive impairment and healthy aging through adaptive computational phenotyping.

PLOS Digit Health. 2026 Sep;5(9):e0001686. Epub 2026 Sep 15
Authors: Hake HS, van der Velde M, Grabowski TJ, van Rijn H, Stocco A
PubMed: 42743227
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Neural Stem Cell-Derived Extracellular Vesicles Improve CNS Delivery and Therapeutic Efficacy of Antisense Oligonucleotide in Amyotrophic Lateral Sclerosis.

J Extracell Vesicles. 2026 Sep;15(9):e70370.
Authors: Zheng Y, Ellison TJ, Garrard R, Gao J, Lai X, Lan L, Xie J, Jiang J, Yao Y
PubMed: 42742464
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Incidence of dementia and mild cognitive impairment in two Indigenous Bolivian cohorts.

Alzheimers Dement. 2026 Sep;22(9):e71750.
Authors: Gatz M, Mack WJ, Eid Rodriguez D, Quispe Gutierrez R, Bani Cuata J, Chui HC, Walters EE, Cummings DK, Hooper PL, Zetterberg H, Finch CE, Trumble BC, Stieglitz J, Gurven MD, Thompson RC, Thomas GS, HORUS Team, Tsimane Health and Life History Project, Kaplan HS
PubMed: 42742085
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Genetic and molecular evidence linking CTSH to Alzheimer's disease pathophysiology.

Alzheimers Dement. 2026 Sep;22(9):e71833.
Authors: Picard C, Aumont-Rodrigue G, Sarty I, Loncke J, Savard M, Maligne-Bruneau L, Poirier J, PREVENT‐AD research group
PubMed: 42741981
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Digital cognitive phenotyping enhances risk stratification in preclinical Alzheimer's disease.

Alzheimers Dement. 2026 Sep;22(9):e71834.
Authors: Vanderlip CR, Stark CE
PubMed: 42741980
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Incidence and risk factors for AD/ADRD among American Indian and Alaska Native US Veterans.

Alzheimers Dement. 2026 Sep;22(9):e71856.
Authors: Dintica CS, Bahorik A, Xia F, Boscardin J, Parko K, Yaffe K
PubMed: 42740335
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Anti-Amyloid Antibodies in the Treatment of Alzheimer's Disease: An Umbrella Review.

J Clin Med. 2026 Sep 1;15(17)
Authors: Kalampokini S, Keramidiotis I, Frontistis A, Zuchi F, Michmizos D, Papaliagkas V, Koutsouraki E
PubMed: 42739787
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The Ocular Microbiome and Alzheimer's Disease: Emerging Insights.

Cells. 2026 Sep 1;15(17)
Authors: Mishra SK, Ozkan J, Su F, Kim WS, Willcox M, Fu Y
PubMed: 42738884
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Photobiomodulation with 808 nm Laser Light Repairs Mitochondrial Integrity and Normalizes ROS, ATP, and Membrane Depolarization in Aβ-Exposed Primary Neurons in Alzheimer's Disease Model.

Int J Mol Sci. 2026 Sep 1;27(17)
Authors: Golovynska I, Li B, Chen Q, Golovynskyi S, Xu H, Stepanov YV, Stepanova LI, Lin F, Qu J, Ohulchanskyy TY
PubMed: 42737733
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Caenorhabditis elegans as a Model for Studying Nrf2/SKN-1 Activation in Alzheimer's Disease: Plant Bioactive Compounds and Therapeutic Translation.

Int J Mol Sci. 2026 Sep 1;27(17)
Authors: Bellver-Sanchis A, Ralchev NR, Romanska PR, Dyakova NK, Ivanova KI, Griñán-Ferré C, Marchev AS
PubMed: 42737730
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Genetic susceptibility of Alzheimer's disease associated with APOE polymorphism: systematic review and bibliometric study.

J Genet Eng Biotechnol. 2026 Sep;24(3):100785. Epub 2026 Aug 4
Authors: Amukti DP, Kusumawardani N, Pratami RI, Purwanto BD, Rukhama RA, Akbar I, Sarwadhamana RJ, Aditya RA, Yuliani S
PubMed: 42749454
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Computational identification of Ginkgo biloba phytochemicals as dual inhibitors of herpes simplex virus type 1 glycoproteins gB and gD targeting its entry and Alzheimer's disease pathogenesis.

J Genet Eng Biotechnol. 2026 Sep;24(3):100728. Epub 2026 Jun 22
Authors: Hossain MM, Shammi SS, Sarwar G, Ahmed S, Fardous J, Morshed MM, Sarker MA, Asaduzzaman M
PubMed: 42749410
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Efficacy and Effectiveness of the Recombinant Zoster Vaccine Against Herpes Zoster, Herpes Zoster Ophthalmicus, Postherpetic Neuralgia and Dementia: A Systematic Review and Meta-Analysis.

Rev Med Virol. 2026 Sep;36(5):e70203.
Authors: Heen E, Øverbø J, Tveteraas IH, Solberg SL, Nøkleby H, Midtbø JE, Di Rusco F, Kasteng F, Ersson A, Andersson S, Johansen K, Juvet LK
PubMed: 42748460
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Unlocking the Potential of Isatin Scaffolds in Acetylcholinesterase Inhibition.

Arch Pharm (Weinheim). 2026 Sep;359(9):e70336.
Authors: Tharwat T, El-Nassan HB, Adly ME, Kamel MM
PubMed: 42748401
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A two-step processing method is recommended to inactivate human sporadic M1 and V2 prions.

J Gen Virol. 2026 Sep;107(9)
Authors: Mohri S, Matsuura Y, Parchi P, Kitamoto T
PubMed: 42747978
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A Pilot Study Evaluating the Effect of Artesunate on Glymphatic-Related Fluid Transport in Parkinson's Disease Mouse Models In Vivo and Ex Vivo.

CNS Neurosci Ther. 2026 Sep;32(9):e71145.
Authors: Han WT, Lu WH, Xu H, Xie GH, Cao Y, Wu XY, Qiu F, Fu T
PubMed: 42747247
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Clinical Practice Outcomes With Lecanemab for Alzheimer Disease.

Neurol Open Access. 2026 Sep;2(3):e000121. Epub 2026 Aug 7
Authors: Liu AJ, Moghadam AA, Alam MS, Lutz MW, Navarra A, Luo S, Wang LA, Petrella JR, Whitson H, O'Brien RJ, Johnson KG, Parker D, Beam C, Sanfilippo M, Al-Sahlani H, Cobb S, Liu MY, Doraiswamy PM
PubMed: 42746606
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[How to Proceed with Diagnosing Memory Loss].

Brain Nerve. 2026 Sep;78(9):1003-1014.
Authors: Ikeda M
PubMed: 42745714
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Rethinking γ-Secretase Dysfunction in Alzheimer's Disease: From APP Processing to Network Perturbation.

J Neurochem. 2026 Sep;170(9):e70550.
Authors: Passarella D, Russo C
PubMed: 42745407
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Evaluating the 8-Year Association Between Cognition and Beta Amyloid in the Dallas Lifespan Brain Study Cohort.

Brain Behav. 2026 Sep;16(9):e71684.
Authors: David J, Torres I, Smith E, Pongpipat E, Park D
PubMed: 42745402
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MARBLE: An in vivo MRI marker of limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC).

Alzheimers Dement. 2026 Sep;22(9):e71832.
Authors: Tazwar M, Evia AM, Ridwan AR, Leurgans SE, Wagner M, Alzheimer's Disease Neuroimaging Initiative, Bennett DA, Schneider JA, Arfanakis K
PubMed: 42745216
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Rethinking tau-targeted therapy in Alzheimer's disease: Toward a dual biomarker strategy.

Alzheimers Dement. 2026 Sep;22(9):e71867.
Authors: Teunissen CE, Pini L, Imbimbo BP
PubMed: 42750203
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Operationalizing Alzheimer's disease trials in the era of targeted therapies.

Alzheimers Dement. 2026 Sep;22(9):e71829.
Authors: Pillai JA, Alladi S, Appleby BS, Brosch JR, Frederiksen KS, Galasko D, Lopez OL, Leverenz JB, Saykin AJ, Schott JM, Seshadri S, Tousi B, Wolk DA
PubMed: 42750195
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Hippocampal snRNA-seq in Collaborative Cross reveals molecular signatures of cognitive resilience independent of chronological aging.

Alzheimers Dement. 2026 Sep;22(9):e71825.
Authors: Chen Y, Ouellette AR, Cao Y, Zhang J, Kaczorowski CC
PubMed: 42750154
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[Lymphatic supermicrosurgery in neurodegenerative disorders].

Ugeskr Laeger. 2026 Aug 31;188(36)
Authors: Salim D, Dalaei F, Beier D, Sørensen JA, Hölmich LR, Thomsen JB
PubMed: 42740552
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Spectral and Directed Connectivity EEG Markers for Classifying Alzheimer's Disease, Frontotemporal Dementia, and Healthy Controls with Exploratory Photobiomodulation Case-Study Projection.

Sensors (Basel). 2026 Aug 31;26(17)
Authors: Šverko Z, Vlahinić S, Vrankić M, Stojković N
PubMed: 42740150
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HIF-2α Depletion and HIF-1α Overexpression in Vulnerable Brain Regions Distinguish Alzheimer's Disease with Cerebral Amyloid Angiopathy.

Int J Mol Sci. 2026 Aug 31;27(17)
Authors: Sukhorukov VS, Baranich TI, Velts OV, Okulova KM, Voronkov DN, Shcherbak EV, Egorova AV, Mudzhiri NM, Lazarev DS, Raksha AP, Yatskovskiy AN, Glinkina VV, Piradov MA
PubMed: 42737681
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Polyamine metabolic enzyme SAT1 remodels the neuronal transcriptome and rescues α-synuclein toxicity in Drosophila.

Amino Acids. 2026 Aug 30;58(1)
Authors: Bangash ZR, Matsui H, Ranxhi B, Todi SV, LeWitt PA, Tsou WL
PubMed: 42734829
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Trajectories of Self-Awareness Across the Alzheimer's Disease Spectrum: A Systematic Review of Its Potential Contribution to Early Diagnosis.

Diagnostics (Basel). 2026 Aug 30;16(17)
Authors: Tsouvala A, Moraitou D, Metallidou P, Tsentidou G, Katsouri IG, Papantoniou G, Sofologi M, Tsolaki M
PubMed: 42739221
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From Single-Modal to Multi-Modal Artificial Intelligence in Alzheimer's Disease: A Systematic Review of Databases, Modalities, Diagnostic Performance, and Clinical Translation Challenges.

Sensors (Basel). 2026 Aug 29;26(17)
Authors: Menezes J, Barbosa MI, Rodrigues PM
PubMed: 42740109
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Lactate Metabolism and Signaling in Amyotrophic Lateral Sclerosis.

Cells. 2026 Aug 29;15(17)
Authors: Ma X, Liu J, Guan Y, Xu C, Li M, Zhang X, Li Z, Zhang L, Wang X, Zhang H, Chen Y
PubMed: 42738864
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Apolipoprotein E Alleles Across the Spectrum of Frontotemporal Lobar Degeneration: A Systematic Review and Meta-Analysis.

Int J Mol Sci. 2026 Aug 29;27(17)
Authors: Liampas I, Polyviou A, Demiri S, Malataras G, Oikonomakis V, Siokas V, Kargiotis O, Kefalopoulou ZM, Chroni E, Dardiotis E
PubMed: 42737648
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Visual and Semiquantitative Assessment of 123I-Ioflupane SPECT in Probable Dementia with Lewy Bodies and Its Association with Autonomic Dysfunction: A Retrospective Study.

J Clin Med. 2026 Aug 28;15(17)
Authors: Arslan T, Bekiş R, Ontan MS, Isik AT
PubMed: 42739651
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Plasma Glial Fibrillary Acidic Protein and Neurofilament Light Chain Concentrations Are Inversely Associated with Retinal Microvascular Perfusion and Vessel Density in Cognitively Normal Individuals with Familial or Genetic Risk Factors for Alzheimer's Disease.

Diagnostics (Basel). 2026 Aug 28;16(17)
Authors: Zhao W, Zhu MY, Patel H, Whitson HE, Johnson KG, Grewal DS, Fekrat S
PubMed: 42739194
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Beneficial Effects of Putative Hydrogen Sulfide (H2S) Donor POM16 in a Genetic Model of Amyotrophic Lateral Sclerosis, FUS [1-359]-Transgenic Mice.

Molecules. 2026 Aug 28;31(17)
Authors: Strekalova T, Gorlova A, Munter JP, Chervinskaya M, Deykin A, Aladysheva Z, Grigorieva E, Lyundup A, Askarova S, Kostin A, Pomytkin I
PubMed: 42738680
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Cox7a2l Variation Influences Complex III and Mitochondrial Supercomplex Differences in 3xTG-AD Mixed-Background Mice.

Int J Mol Sci. 2026 Aug 28;27(17)
Authors: Ma W, Cavarsan C, Bazinet LF, Silvia SM, Owusu-Sarfo J, Atoyan J, Davis J, Van Nostrand WE, Robinson JK, Clements RT
PubMed: 42737607
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Electrodermal Activity as a Potential Diagnostic Biomarker for Alzheimer's Disease: A Pilot Study.

Sensors (Basel). 2026 Aug 27;26(17)
Authors: Pandian S, Mercado-Diaz LR, Ruiz-Trivino J, Aguillon D, Posada-Quintero H
PubMed: 42740027
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LncRNA Gas5, a Target of the Nonsense-Mediated Decay Pathway in the Brain, Regulates Neuroinflammation and Neurodegenerative Disease Pathways in a Tauopathy Mouse Model.

Int J Mol Sci. 2026 Aug 27;27(17)
Authors: Krause-Hauch M, Wang B, Patel RS, Verdina L, Hedrick A, Blair LJ, Dharap A, Cai J, Patel NA
PubMed: 42737576
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The Innate Immune Memory That Bites Back: How Periodontitis May Train Neuroinflammation in Alzheimer's Disease.

Int J Mol Sci. 2026 Aug 27;27(17)
Authors: Valladares KN, Fields JL, Katz J, Michalek S, Zhang P
PubMed: 42737563
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Application of Mesenchymal Stromal Cells and Their Exosomes in Neurodegenerative Diseases and Lysosomal Storage Diseases.

Cells. 2026 Aug 26;15(17)
Authors: Ayupova AI, Sidorova AS, Luzina EA, Sufianov AA, Sufianova GZ, Zaynutdinov AM, Rizvanov AA, Solovyeva VV
PubMed: 42738833
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Sigma-1 Receptor Stimulation Rescues FTD/ALS Mutant TDP43-Induced Disruption of the VAPB-PTPIP51 ER-Mitochondria Tethering Proteins via Inhibition of GSK3β.

Cells. 2026 Aug 26;15(17)
Authors: Blair K, Gosset P, Martinez-Serra R, Mórotz GM, Martín-Guerrero SM, Gomez-Suaga P, Atherton J, Mitchell JC, Noble W, Miller CC, Markovinovic A
PubMed: 42738830
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Rare Variants May Influence Disease Risk and Clinical Features in Sporadic Late-Onset Chinese Parkinson's Disease Patients.

Int J Mol Sci. 2026 Aug 26;27(17)
Authors: Ho RW, Xiong Z, Lo RC, Liu H, Ho PW, Sham PC, Ho SL, Pang SY
PubMed: 42737551
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Effects of a Combined Vitamin D3 and Docosahexaenoic Acid Intervention on Cognitive Function and Blood Pyroptotic Biomarkers in Older Adults with Mild Cognitive Impairment: A 12-Month Randomized, Double-Blind, Placebo-Controlled Trial.

Nutrients. 2026 Aug 25;18(17)
Authors: Yuan J, Yang R, Chen H, Zhao H, Chen X, Lou Z, Han X, Ma F
PubMed: 42738950
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LRRK2: Molecular Mechanisms in Parkinson's Disease.

Int J Mol Sci. 2026 Aug 25;27(17)
Authors: Arias-Carrión O, Guerra-Crespo M, Ortuño-Sahagún D, Ortega-Robles E
PubMed: 42737506
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Plasma p-Tau217 and SPECT-Based eZIS in Mild Cognitive Impairment: Concordance Analysis with Validation in an Amyloid PET Sub-Cohort.

Diagnostics (Basel). 2026 Aug 24;16(17)
Authors: Huang IL, Matsuda H, Pai YT, Pai MC
PubMed: 42739134
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Assessment of the Association of Periodontitis and Diabetes Mellitus with Alzheimer's Disease in a Mouse Model.

Int J Mol Sci. 2026 Aug 23;27(17)
Authors: Nakahara M, Kataoka K, Maruyama T, Nurhamim M, Zhang Y, Fukuhara D, Uchida-Fukuhara Y, Islam MM, Morita M, Saito T, Ekuni D
PubMed: 42737444
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APOE genotypes differentially remodel the astrocytic lipid droplet proteome to shape lipid droplet dynamics.

Nat Commun. 2026 Aug 19;17(1)
Authors: Cuní-López C, Root JT, Hao Y, Blomberg N, Koppes-den Hertog SJ, Sacks D, Trujillo AE, Ghirlando R, Kowal I, Epstein J, Yang LG, Cookson MR, Marsan E, van der Kant R, Giera M, Qi YA, Narayan PS
PubMed: 42749735
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Microglia deploy TAM receptors to kill motor neurons in a mouse model of amyotrophic lateral sclerosis.

Nat Commun. 2026 Aug 15;17(1)
Authors: Huang Y, Mavinkurve A, Sabikunnahar B, Stevens B, Lemke G
PubMed: 42744804
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TogoPhosTAC as a delivery-ready platform for targeted protein dephosphorylation.

Nat Commun. 2026 Aug 14;17(1)
Authors: Chen YY, Ke DT, Lee YC, Chen HR, Lin HY, Yeh CH, Ko YC, Tu MH, Yu CH, Hu Z, Chen PH
PubMed: 42733006
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Effects of homozygous PARK7 gene mutations L166P and M26I on BNIP3/BNIP3L interactions and ER-mitochondria proximity.

Biol Direct. 2026 Aug 5;21(1)
Authors: Wu J, Jin K, Shen M, Lai X, Guo J, Wang T, Tian Z, Yan J
PubMed: 42723107
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Gut Microbiota, Neuroinflammation, and Autonomic Dysfunction in Neurodegenerative Diseases: A Systematic Review of Mechanistic and Translational Evidence.

Cureus. 2026 Aug;18(8):e114312. Epub 2026 Aug 10
Authors: Alauddin W, Srivastava C, Goyal P, Shukla M, Garg DK, Prajesh BR, Singh S, Shaikh FI, Khairnar S
PubMed: 42724165
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Dimethylarginine Dimethylaminohydrolase 1 (DDAH1)-Arginine Metabolic Axis Is Independently Associated With Alzheimer's Disease Risk in the UK Biobank.

Cureus. 2026 Aug;18(8):e114415. Epub 2026 Aug 12
Authors: Lehrer S, Rheinstein P
PubMed: 42729959
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Demographic and Clinical Characteristics of Patients Treated With Lecanemab Stratified by Amyloid-Related Imaging Abnormality Status.

Cureus. 2026 Aug;18(8):e114472. Epub 2026 Aug 13
Authors: Rohatgi S, Younan CM, Martinez Imbett RE, Ford JN, Wleklinski M, Zhu S, Romero J
PubMed: 42732414
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Regional juxtacortical microstructural changes and gene expression provide insights into neurodegeneration in Alzheimer's disease.

Transl Psychiatry. 2026 Jul 30;16(1)
Authors: Zhang J, Sun L, Yang X, Kang L, Zheng Y, Huang Q, Xu W, Guan Y, Liu J, Deng Y, Xie F, Xu X, Li B, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42744775
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Metabolism and oxygen tension in Alzheimer's disease mouse model using two-photon FLIM-PLIM microscopy.

Neurophotonics. 2026 Jul;13(3):035008. Epub 2026 Sep 11
Authors: Sagar VK, Wallrabe H, Alam SR, Pardo E, Becker W, Norambuena A, Periasamy A
PubMed: 42730105
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Cohort profile: a community-based prospective cohort study of Alzheimer's disease and related dementias in the Democratic Republic of Congo.

Alzheimers Dement Behav Socioecon Aging. 2026 Jun;2(2):e70085. Epub 2026 Jun 6
Authors: Ikanga J, Obenauf C, Patel SS, Schwinne M, Gikelekele G, Epenge E, Potshi JM, Tomadia T, Kazadi J, Kavugho I, Santolini GL, Nkosi A, Sabowa FM, Musewu BM, Mawisa E, Tsangu JP, Beya FM, Mampunza S, Mananga L, Bukabau J, Teunissen CE, Karikari T, Gross AL, Rojas JC, Alonso A
PubMed: 42751573
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Abortive transcripts in exosomes - A potential biomarker for Alzheimer's disease.

PLoS One. 2026;21(9):e0357752. Epub 2026 Sep 11
Authors: Wu H, Zhang N, Yan W, Li C, Zhang X, Xv X, Fang F, Qin S, Zhao L
PubMed: 42726720
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Utilization of transcranial direct current stimulation for neuromodulation in frontotemporal dementia.

Ind Psychiatry J. 2026;35(2):231-233. Epub 2026 May 22
Authors: Sinha SS, Ashwin JV, Singh N, Shahi MK, Kar SK, Singh B
PubMed: 42725249
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Interpretable self-supervised transformers for resting-state EEG analysis in Alzheimer's disease.

Front Neuroinform. 2026;20:1899573. Epub 2026 Aug 27
Authors: Zareen SS, Alzaben N, Ahmad U, Alam TM, Algarni A, Wang J
PubMed: 42725030
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The gut-brain axis in Alzheimer's disease: traditional Chinese medicine constituents as modulators of gut-brain homeostasis.

Front Microbiol. 2026;17:1852198. Epub 2026 Aug 27
Authors: Liang Y, Kong Q, Du X, Sun Y, Wang S
PubMed: 42725024
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Transcriptomic signatures as biomarkers for the progression of mild cognitive impairment.

Front Aging Neurosci. 2026;18:1901264. Epub 2026 Aug 27
Authors: Yang J, Li J, Mao L, Ren H, Li Q, Geng X, Lu Q, Peng C, Zhang J, Liu X, Zhang Y, Zhu B, Jiang T, Yang J
PubMed: 42724701
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Mitochondrial ecosystem restoration in Alzheimer's disease: from mechanisms to multi-target therapeutic strategies.

Front Cell Dev Biol. 2026;14:1886145. Epub 2026 Aug 27
Authors: Song D
PubMed: 42724487
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Polygenic score for sleep duration in relation to the risk of Alzheimer's disease: results from the UK biobank.

Front Dement. 2026;5:1843867. Epub 2026 Aug 27
Authors: Wong AT, Floud S, Reeves GK, Holmes MV, Travis RC, van Duijn CM, Doherty A, Smith-Byrne K
PubMed: 42724004
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Expression differences and diagnostic efficacy of core plasma biomarkers in Alzheimer's disease, cerebral small vessel disease and healthy adults.

Front Neurol. 2026;17:1934127. Epub 2026 Aug 27
Authors: Xiandong W, Junqi W, Xuan Z, Daichao M, Xiaoyan Z, Lihua H, Hui Z
PubMed: 42723835
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Interpretable AI for neural signal decoding in dementia: an EEG ensemble approach to differential diagnosis.

Front Neuroinform. 2026;20:1902549. Epub 2026 Aug 27
Authors: Muhammad F, Usmani IA, Aamir M, Alduailij M, Marzougui M, Nawaz R
PubMed: 42723800
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ZDWX-25, a dual DYRK1A/GSK3β inhibitor, attenuates tau hyperphosphorylation and neuroinflammation in acute mouse models.

Front Pharmacol. 2026;17:1892218. Epub 2026 Aug 27
Authors: Wang W, Xing Y, Xu Z, Liu S, Zhou L, Ning X, Li X, Zheng F, Yang A, Li Z, Ren M, Xu Z, Zhao Q
PubMed: 42723786
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Integrated multi-omics identification of m6A-SNP-related diagnostic biomarkers in amyotrophic lateral sclerosis.

Front Immunol. 2026;17:1914869. Epub 2026 Aug 27
Authors: Wang H, Sun B, Wang S, Pan J, Du R, Pang X, Bai J, Han J, Feng J
PubMed: 42723774
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Query-based multimodal interaction and adaptive gated fusion for Alzheimer's disease detection.

Front Aging Neurosci. 2026;18:1913697. Epub 2026 Aug 27
Authors: Shao Y, Tan C, Huo H, Fang T
PubMed: 42723693
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Parallel multilink group joint ICA (pmg-jICA): Fusion of 3D structural and 4D functional data across multiple resting fMRI networks.

Netw Neurosci. 2026;10(3):787-808. Epub 2026 Aug 25
Authors: Khalilullah KM, Phadikar S, Agcaoglu O, Sui J, Duda M, Adali T, Calhoun VD
PubMed: 42730199
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Slow-4 cerebellar activity tracks MMSE language-related task performance across the Alzheimer's disease spectrum: a multi-metric resting-state fMRI study.

Front Neurosci. 2026;20:1820150. Epub 2026 Aug 28
Authors: Mao H, Fu B, Song J, Jia X, Cheng L, Xiao H, Zhang L
PubMed: 42730172
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Developmental brain programmes and biomarker activation in Alzheimer's disease.

Brain Commun. 2026;8(5):fcag337. Epub 2026 Sep 3
Authors: Pini L, Margoni M, Filippi M, Imbimbo BP
PubMed: 42729944
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Peripheral-central inflammatory crosstalk in Alzheimer's disease: immunometabolic functions of circulating soluble metabolites under dynamic blood-brain barrier states.

Front Immunol. 2026;17:1939482. Epub 2026 Aug 28
Authors: Song N, Xing H, Liu F, Xi W
PubMed: 42729804
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Spatial covariance of mGluR5 density and structural degeneration in behavioral variant frontotemporal degeneration.

Imaging Neurosci (Camb). 2026;4 Epub 2026 Sep 10
Authors: Matyi MA, Pecsok MK, Olm CA, Radhakrishnan H, Dratch L, Van Deerlin VM, Rhodes E, Phillips JS, Cook PA, Gee JC, Irwin DJ, McMillan CT, Roalf D, Massimo L
PubMed: 42729732
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Glycyrrhiza glabra exhibits disease-modifying effects in Alzheimer's disease through restoration of mitochondrial function, synaptic plasticity, and kinase signaling.

Front Pharmacol. 2026;17:1894678. Epub 2026 Aug 28
Authors: Amrutha S, Kadandelu M, Paidi MK, Raghu SV, Prasad TS, Modi PK
PubMed: 42729566
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Hippocampal mediation in the lipid-Alzheimer's disease pathway: A high-dimensional mediation analysis stratified by APOE and sex.

Alzheimers Dement (N Y). 2026;12(3):e70314. Epub 2026 Sep 10
Authors: Cao Y, Fan Y, Meng Q, Wang J, Chen R, Alzheimer's Disease Neuroimaging Initiative, Alzheimer's Disease Metabolomics Consortium
PubMed: 42729514
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Real-world anti-amyloid therapy beyond traditional symptomatic populations: a longitudinal case series.

Front Psychiatry. 2026;17:1900651. Epub 2026 Aug 28
Authors: Han J, Fang Y, Esiaka D, Abraham O
PubMed: 42729372
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A guide to selecting high-performing antibodies for TMEM175 (UniProt ID: Q9BSA9) for use in western blot, immunoprecipitation, and immunofluorescence.

F1000Res. 2026;15:942. Epub 2026 Jun 16
Authors: Moleón VR, Alende C, Fothouhi M, Bolívar SG, Ayoubi R, Francis V, McPherson PS, Laflamme C
PubMed: 42728995
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A guide to selecting high-performing antibodies for DJ-1 ( PARK7) (Q99497) for use in western blot, immunoprecipitation, and immunofluorescence.

F1000Res. 2026;15:989. Epub 2026 Jun 23
Authors: Zha C, Alende C, Fotouhi M, Bolívar SG, Ayoubi R, Francis V, McPherson PS, Laflamme C
PubMed: 42728985
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Whole-mount diffracted X-ray blinking analysis of intracellular amyloid-β-associated nanoscale dynamics in Caenorhabditis elegans.

Biol Methods Protoc. 2026;11(1):bpag044. Epub 2026 Aug 13
Authors: Ozaki K, Shinkai Y, Sasaki YC, Kuramochi M
PubMed: 42732361
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Factors associated with phlebotomy failure in an Alzheimer's Disease Research Center cohort.

Alzheimers Dement (N Y). 2026;12(3):e70322. Epub 2026 Sep 11
Authors: Pawlus MC, Gorham A, Suarez-Rodriguez C, Risal I, Galvez MA, Simpson BK, Celedon J, Noori A, Ramirez-Gomez L, Das S, Arnold SE, Kivisäkk P, Serrano-Pozo A
PubMed: 42732163
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Health-related factors and their impact on blood-based biomarkers of Alzheimer's disease.

Aging Brain. 2026;10:100166. Epub 2026 Sep 3
Authors: Kurz C, Taute M, Tegethoff P, Hufnagel A, Leonhardt S, Gürsel SÜ, Koriath C, Jethwa A, Kollmorgen G, Bittner T, Keeser D, Brendel M, Haeckert J, Utecht J, Papazov B, Levin J, Höglinger G, Rauchmann BS, Perneczky R
PubMed: 42733904
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Insulin resistance increases the risk of conversion to the subcortical small vessel type of dementia.

Cereb Circ Cogn Behav. 2026;11:100561. Epub 2026 Aug 27
Authors: Axelsson Andrén E, Kettunen P, Wallin A, Svensson J
PubMed: 42733490
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Novel 1,4-Diazepane derivatives as amyloid-beta (Aβ) aggregation inhibitors.

Front Chem. 2026;14:1919936. Epub 2026 Sep 1
Authors: Karuturi RC, Hefny AA, Shakeri A, Rao PP
PubMed: 42741787
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Alzheimer's disease heterogeneity and co-pathologies: Defining novel targets, biomarkers, modalities, and research methodologies.

Alzheimers Dement (N Y). 2026;12(3):e70287. Epub 2026 Sep 14
Authors: Tansey MG, Bozeat S, Ackerman P, Atri A, Barnum CJ, Brundin P, de Carvalho CA, Fleisher AS, Graf A, Head E, Kerchner GA, Kolb HC, Koyama A, Kozberg M, Leyns CE, Llibre-Guerra JJ, Mattsson-Carlgren N, McKissock D, Murray ME, Rosenthal LS, Rubel C, Schindler SE, Schneider JA, Schwarz AJ, Scott KM, Seredenina T, Tosun D, Wallings RL, Wang H, Wilcock DM, Carrillo M, Mahinrad S, Weber CJ
PubMed: 42741654
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Inflammation and neuropsychiatric symptoms in Parkinson's disease: a genetic association.

Front Aging Neurosci. 2026;18:1877657. Epub 2026 Aug 31
Authors: Gonçalves AR, Mendes A, Damásio J, Vila-Chã N, Boleixa D, Santos C, Leal B, Cavaco S
PubMed: 42741404
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Editorial: Cellular and animal models of neurodegenerative and neuroinflammatory conditions.

Front Cell Neurosci. 2026;20:1961369. Epub 2026 Aug 31
Authors: García-León JA, García-Díaz B, Baglietto-Vargas D, Rodriguez-Ortiz CJ
PubMed: 42741375
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Utilising speech-derived biomarkers to detect Alzheimer's disease with BERT-based language models: a machine learning study.

Front Artif Intell. 2026;9:1875702. Epub 2026 Aug 31
Authors: Khanna Z, Ho D, Remus A, Raczkowska M, Montalan R, Saha P
PubMed: 42741373
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Interpretable machine learning model based on multimodal MRI radiomics for Alzheimer's disease diagnosis.

Front Aging Neurosci. 2026;18:1876233. Epub 2026 Aug 31
Authors: Keranmu N, Aizezi D, Pan X, Yang L, Liu Y, Liu J
PubMed: 42741328
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The spectrum of C9orf72 repeat lengths in Portuguese frontotemporal dementia and amyotrophic lateral sclerosis patients: from pathogenic expansions to intermediate alleles.

Front Neurosci. 2026;20:1913909. Epub 2026 Aug 31
Authors: Almeida MR, Tábuas-Pereira M, Matos A, Santos A, Teixeira C, Baldeiras I, Lima M, Santana I
PubMed: 42741310
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Serum metabolomic profiling following cerebellar repetitive transcranial magnetic stimulation combined with cognitive training on Alzheimer's disease.

Front Neurol. 2026;17:1887127. Epub 2026 Aug 31
Authors: Chen Y, Shi J
PubMed: 42741217
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Linking cognitive variability and Alzheimer's disease biomarkers by neurocognitive status.

Alzheimers Dement (Amst). 2026;18(3):e70481. Epub 2026 Sep 13
Authors: Lin SS, Milam A, Kiselica AM, Aita SL, Saeed M, Webber T, Woods SP, Borgogna NC, Walker KA, Kamath V, Visscher K, Murchison CF, Geldmacher DS, Roberson ED, Hill BD, Bene VA
PubMed: 42741049
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AST/ALT, APOE ε4, and Alzheimer's disease progression: A longitudinal cohort study.

Alzheimers Dement (Amst). 2026;18(3):e70484. Epub 2026 Sep 13
Authors: Ahn YH, Yang CM, Kim DJ, Lee SH, Jung YH, Lee SY, Yoon SH, Alzheimer's Disease Neuroimaging Initiative
PubMed: 42741023
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Emerging therapeutic targets beyond amyloid and tau in Alzheimer's Disease: Implications for lifestyle, metabolism and preventive medicine.

Wiad Lek. 2026;79(7):1685-1691.
Authors: Izhytska N, Sobczyk KA, Ogrodnik KW, Mazurkiewicz M, Malentowicz D, Szafraniec NJ, Brożyna D, Sałapski B, Pastuszka M
PubMed: 42748320
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Response: Beyond Oral Hygiene: Medication Burden, Oral Function, and Dysphagia in Alzheimer's Disease.

Spec Care Dentist. 2026;46(5):e70258.
Authors: Silva MG, Vasconcelos MB, Silva RG, Feitosa MÁ
PubMed: 42746891
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Designing intranasal formulations for Alzheimer's disease: A material-based perspective.

Tzu Chi Med J. 2026;38(4):446-456. Epub 2026 Jun 5
Authors: Chen YS, Huang HY
PubMed: 42746628
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Time to diagnosis in FTLD-associated syndromes in Latin America.

Alzheimers Dement (Amst). 2026;18(3):e70476. Epub 2026 Sep 15
Authors: Magrath-Guimet N, Morello-Garcia F, De Los Santos L, Ardohain-Cristalli C, Tabernero E, Chaves H, Bagnati P, Allegri RF, Migeot J, Acosta-Uribe J, Allen IE, Aguillon D, Avila-Funes JA, Behrens MI, Bruno M, Brusco LI, Custodio N, Resende EP, Aniotz CD, Gorno-Tempini M, Ibanez A, Kosik KS, Maito MA, Matallana D, Miller B, Nalls M, Piña-Escudero SD, Possin K, Rocatti G, Santamaria-Garcia H, Slachevsky A, Sosa AL, Takada L, Taylor JW, Zapata-Restrepo LM, Yokoyama JS, Valcour V
PubMed: 42746372
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Cerebral oxygen extraction fraction as an emerging imaging biomarker in mild cognitive impairment and dementia.

Dement Neuropsychol. 2026;20:e20250412. Epub 2026 Sep 14
Authors: Hussain JM, Lashari A, Nageen W, Siddiqui A, Waris A, Maliha S, Mudasir A, Rehman MB, Rahman MH
PubMed: 42746331
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Effects of long-term daily supplementation with vitamin D3 and marine omega-3 fatty acids on change in ADRD biomarkers: A secondary analysis of a randomized clinical trial.

Alzheimers Dement (N Y). 2026;12(3):e70312. Epub 2026 Sep 14
Authors: Vyas CM, Ostaszewski BL, Anderson AK, Cook NR, Kang JH, Mischoulon D, Reynolds CF 3rd, Chang G, Gatchel JR, Manson JE, Selkoe DJ, Okereke OI
PubMed: 42746141
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Effect of choline supplementation in presymptomatic APOE ε4 carriers: a pilot study.

Alzheimers Dement (N Y). 2026;12(3):e70323. Epub 2026 Sep 14
Authors: Ray WJ, Lightfoot YL, Trinh RT, Fawver-Kahle J, Cooper S, Tsai LH, Bortz J, Trujillo-Gonzalez I, Zhang T, Wu H, Iv GJ, Schulz PE
PubMed: 42746101
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Targeting protein aggregate co-pathologies in neurodegeneration: a viable therapeutic strategy?

Mol Neurodegener Adv. 2026;2(1):38. Epub 2026 Sep 14
Authors: Buck SA, Madhavan SS, Sanders LH
PubMed: 42745993
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Autophagy-lysosomal pathway in neurodegeneration.

Mol Neurodegener Adv. 2026;2(1):37. Epub 2026 Sep 14
Authors: McDonough SR, Rao AK, McAleer JM, Babrowicz BM, Sharma M
PubMed: 42745943
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P-tau181 is longitudinally associated with a proxy measure of mild behavioral impairment among frail older adults: Insights from COGFRAIL.

Alzheimers Dement (Amst). 2026;18(3):e70392. Epub 2026 Sep 14
Authors: Bellelli F, González E, Peluso A, Angioni D, Sourdet S, Martin MS
PubMed: 42745934
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Imaging for anti-amyloid therapy eligibility: Comparing GRE and SWI in detecting microhemorrhages and superficial siderosis.

Alzheimers Dement (Amst). 2026;18(3):e70477. Epub 2026 Sep 14
Authors: Ford JN, Ferraciolli SF, Chagui OG, Iii MR, Cadavid EC, Dickson J, Vejdani-Jahromi M, DeSalvo MN, Gomez LA, Yee S, Griffin HR, Kozak B, Rohatgi S, Huang RY, Gomez-Isla T, Romero J
PubMed: 42745918
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Beyond Oral Hygiene: Medication Burden, Oral Function, and Dysphagia in Alzheimer's Disease.

Spec Care Dentist. 2026;46(5):e70255.
Authors: Misra SR, Das R
PubMed: 42753133
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Bioinformatics-Driven Discovery of Aβ-Targeted Therapeutics and Diagnostic Biomarkers for Alzheimer's Disease.

Biomed Res Int. 2026;2026(1):e8975137.
Authors: Li X, Liu X, Song X, Zhou Y, Yang D, Wang Y, Mao S, Rang X, Hong X, Wang X, Yue H, Wang D, Zhang X
PubMed: 42752992
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Neuroprotective Effects of Two N-Benzylamides in Models of Oxidative Stress, Neurite Outgrowth and Neurodegeneration.

Oxid Med Cell Longev. 2026;2026(1):e3092494.
Authors: Mamangam S, Dhanabalan AK, Verma K, Prasanth MI, Brimson S, Brimson JM
PubMed: 42751784
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Pollutants regulate changes in pathological markers of neurodegenerative diseases: a new perspective in environmental toxicology.

Front Toxicol. 2026;8:1814795. Epub 2026 Sep 3
Authors: Kou X, Hu Q, Kou Y, An D
PubMed: 42751714
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Alzheimer's disease: genetic background in the era of next-generation sequencing technologies.

Brain Commun. 2026;8(5):fcag332. Epub 2026 Sep 16
Authors: Lukyova L, Zatkova A, Minarik J, Holesova Z, Budis J, Kucharik M, Benes V, Gazdarica J, Szemes T
PubMed: 42751194
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Aducanumab

2026 Jan; StatPearls Publishing, Treasure Island (FL)
Authors: Padda IS, Preuss CV, Parmar M
PubMed: 34424635
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Neuropsychological Assessment

2026 Jan; StatPearls Publishing, Treasure Island (FL)
Authors: Schaefer LA, Sharma NP
PubMed: 30020682
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