Alzforum - Papers of the Week: 14-20 Aug 2026

Mechanistic convergence of Astragalus-derived phytochemicals in Alzheimer's disease: A systematic review.

IBRO Neurosci Rep. 2026 Dec;21:450-463. Epub 2026 Jul 31
Authors: Bhatt Y
PubMed: 42598552
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Meta-analysis and pharmacoeconomic study of rasagiline versus selegiline in the treatment of Parkinson's disease.

Ann Med. 2026 Dec;58(1):2711475. Epub 2026 Aug 19
Authors: Zhou H, Li D, Yu J, Gu Z, Wei H
PubMed: 42615806
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A robust HPLC-HILIC enrichment system for O-glycoproteomics profiling of plasma and cerebrospinal fluid across Alzheimer's disease progression.

Anal Chim Acta. 2026 Oct 15;1419:345899. Epub 2026 Jun 26
Authors: Deng Z, Wang Y, Liu L, Guo X, Zhu H, Dong M, Ge Y, Yu Y, Ye M
PubMed: 42618108
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A dual-enhanced magnetically separable SERS strategy enabled by Fe3O4@Au nanovilli and UiO-66-NH2 for ultrasensitive detection of p-tau217.

Anal Chim Acta. 2026 Oct 15;1419:345893. Epub 2026 Jun 25
Authors: Chen J, Liang Y, Xu P, Kong C, Zhang Y, Zhou R, Wu O, Jiang Z, Zhao H, Song M, Jiang T, Pan Y
PubMed: 42618102
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Differential effects of P2Y12 inhibition on sleep and glymphatic function in male and female mice.

Brain Behav Immun Health. 2026 Oct;56:101330. Epub 2026 Aug 14
Authors: Su L, Tian M, Zhang S, Gao P, Zhang X, Xie M, Liu X, Xu W, Yao E
PubMed: 42614582
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Neutralization of pathogenic PC-OxPL by AAV-delivered scFv as a therapeutic strategy for amyotrophic lateral sclerosis.

Mol Ther Adv. 2026 Sep 10;34(3):201822. Epub 2026 Jul 29
Authors: Gomes-Duarte A, Wong JK, Moro A, Pasteuning-Vuhman S, Pos W, Haselberg R, Sogorb-González M, Pascoal S, Borst L, Chatterjee M, Giera M, Tsimikas S, Sadiq SA, van Deventer S
PubMed: 42614391
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i.c.v. delivery of AAV9-synapsin-promoted caveolin-1 attenuates neuromuscular deficits and neuromuscular degeneration in hSOD1G93A mice.

Mol Ther Adv. 2026 Sep 10;34(3):201820. Epub 2026 Jul 27
Authors: Watanabe N, Kawahori Y, Ta V, Wang D, Ohgi KA, Wang H, Kleschevnikova N, Ishikawa E, Head BP
PubMed: 42614372
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Antisense oligonucleotide treatment following viral delivery of artificial SOD1-targeting miRNA shows improved efficacy in SOD1-G93A mice.

Mol Ther Adv. 2026 Sep 10;34(3):201818. Epub 2026 Jul 24
Authors: Hawley ZC, Guise AJ, Pardo ID, Chowdhury T, Hana S, Zavodszky MI, Engle L, Wiltberger K, Bartlett D, Raitcheva D, Bommegowda S, Lee WH, Chen SK, Sheehy A, Driscoll R, Peterson M, Sebalusky J, Hamann S, Marsh G, Doherty J, Chicoine KE, Cundiff P, Dwyer S, Clarner P, Zeng W, Ferretti D, Tuczkewycz T, Isaza I, Patrovanie M, Mcgladrigan C, Chu J, Morrison JP, Arnold HM, Shen S, Hurt JA, Trapa P, Graham DL, Plowey ED, Lo SC
PubMed: 42620667
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DTI-ALPS as a marker of glymphatic function: Review of the literature findings, methodology, and interpretation.

Neuroimage Rep. 2026 Sep;6(3):100394. Epub 2026 Aug 6
Authors: Maller JJ, Magnotta VA
PubMed: 42602456
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The Gut-Brain Axis in Neurodegeneration: Mechanistic Links Between Dysbiosis and Neuropathology.

Iran J Pathol. 2026 Sep 1;21(4):507-522. Epub 2026 Aug 1
Authors: Azimzadeh M, Ababzadeh S, Kahaki AG, Babaei SM, Seyedebrahimi R, Farsani ME
PubMed: 42602177
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Efficacy and Safety of Electroconvulsive Therapy for Dementia With Lewy Bodies, Its Prodromal Phase, and Parkinson's Disease Dementia: Eight Cases Encountered at Our Institution.

Psychogeriatrics. 2026 Sep;26(5):e70204.
Authors: Fukatsu T, Fujita K, Yoshida T, Kawai M, Miyata J
PubMed: 42604817
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Fisetin Attenuates Amyloid-Beta-Induced Neurotoxicity in Human Neuroblastoma SH-SY5Y Cells: Integrating In Silico Target Prediction and In Vitro Validation.

J Biochem Mol Toxicol. 2026 Sep;40(9):e71076.
Authors: Jaiswal C, Singh I, Singh AK
PubMed: 42606694
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Domain-specific physical activity levels and risk of dementia: a systematic review and meta-analysis.

Lancet Public Health. 2026 Sep;11(9):e650-e664.
Authors: Feter N, Iso-Markku P, Markarian T, Luong DM, Gunnink J, Schröder N, Caputo EL, Feter J, Nanda A, Hourihan S, da Silva GS, Ventura A, Bumaguin DB, Klimentidis YC, Alexander GE, Umpierre D, Hallal PC, Rombaldi AJ, Raichlen DA
PubMed: 42612650
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Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets.

MedComm (2020). 2026 Sep;7(9):e70915. Epub 2026 Aug 17
Authors: Li T, Zhang Q, Wu Y, Huang R
PubMed: 42609516
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Toward Precision Neuropsychiatry of Dementia: Neuropsychiatric Symptoms as Multidimensional Clinical Phenotypes.

Psychogeriatrics. 2026 Sep;26(5):e70209.
Authors: Shinagawa S, Nagata T
PubMed: 42608660
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Ferroptosis and NMDA Receptor Activity in Alzheimer's Disease: Implications for Amyloid Pathology and P-Glycoprotein Regulation.

Drug Dev Res. 2026 Sep;87(6):e70367.
Authors: Salunkhe J, Ugale V
PubMed: 42616564
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Multimerization of a rationally designed nanobody for enhanced avidity toward Aβ42 oligomers.

Protein Sci. 2026 Sep;35(9):e70754.
Authors: Nowinska M, Suh E, Mogilevsky C, Vendruscolo M
PubMed: 42615560
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Rostral associations of MRI atrophy of the amygdala and entorhinal cortex across the AD spectrum.

Neuroimage Rep. 2026 Sep;6(3):100392. Epub 2026 Aug 10
Authors: Miller MI, Xie Y, Stouffer KM, Ceritoglu C, Li J, Ratnanather JT, Younes L, Bakker A, Rani N, Albert MS, Troncoso JC, Morris M
PubMed: 42620569
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Anatomy of a Setback: A Taxonomy of Clinical Trial Failures in Alzheimer's Disease and Strategic Lessons for the Future.

FASEB J. 2026 Aug 31;40(16):e72221.
Authors: Emanuele E, Minoretti P
PubMed: 42619623
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Neuronal overexpression of Kcnn1 in A53T α-synuclein mice suppresses phospho-serine 129 α-synuclein formation and doubles survival time.

Proc Natl Acad Sci U S A. 2026 Aug 25;123(34):e2622262123. Epub 2026 Aug 19
Authors: Nagy M, Fenton WA, Horwich AL
PubMed: 42616775
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Risk of transmission of amyloid β pathology via transfused blood products.

Lancet. 2026 Aug 22;408(10556):753-760.
Authors: Banerjee G, Edgren G, Zhao J, Ferguson NM, Harvala H, Hope J, Jackson GS, Lowry PJ, Mead S, Purro SA, Schott JM, Turner ML, Werring DJ, Zetterberg H, Collinge J
PubMed: 42624157
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Gut microbiota-derived extracellular vesicles in Parkinson's disease.

iScience. 2026 Aug 21;29(8):117057. Epub 2026 Aug 5
Authors: Karikka S, Tejesvi MV, Hekkala J, Turunen J, Kaisanlahti A, Virtanen N, Mishra S, Zhyvolozhnyi A, Sinkkonen N, Suokas M, Meriläinen S, Erawijantari PP, Lahti L, Saarnio J, Krüger J, Portaankorva AM, Vainio SJ, Ruuska-Loewald T, Reunanen J, Samoylenko A
PubMed: 42602545
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Language-enhanced generative modeling for amyloid PET synthesis from MRI and blood biomarkers.

iScience. 2026 Aug 21;29(8):117122. Epub 2026 Aug 10
Authors: Zhang Z, Mao X, Guo Q, Zhang S, Huang Q, Zhou M, Xie F, Liu M
PubMed: 42620814
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Multi-region brain transcriptomes uncover two subtypes of aging individuals with differences in Alzheimer risk and the impact of APOEε4.

iScience. 2026 Aug 21;29(8):117038. Epub 2026 Aug 10
Authors: Lee AJ, Ma Y, Yu L, Dawe RJ, McCabe C, Arfanakis K, Mayeux R, Bennett DA, Klein HU, De Jager PL
PubMed: 42620705
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Regionally heterogeneous gamma alterations and their diagnostic value in early-onset Alzheimer's disease.

Int J Psychophysiol. 2026 Aug 20;228:113454. Epub 2026 Aug 20
Authors: Fide E, Yerlikaya D, Ada E, Yener G
PubMed: 42617666
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Hierarchical Inference Dysfunction in Autism and Alzheimer's Disease: A Conceptual Predictive-Coding Framework From Hyper-Precision to Predictive Collapse.

Eur J Pharmacol. 2026 Aug 20;:179276. Epub 2026 Aug 20
Authors: Coccurello R
PubMed: 42624451
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Bone marrow remodeling and brain-bone marrow crosstalk in Alzheimer's disease-like neurodegeneration.

Brain Behav Immun. 2026 Aug 20;:106968. Epub 2026 Aug 20
Authors: Yenkoyan K, Davtyan T, Torosyan H, Galstian S, Chavushyan V
PubMed: 42624382
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Mitochondrial dysfunction in neurodegenerative diseases: Mechanisms and therapeutic advances.

Ageing Res Rev. 2026 Aug 20;122:103312. Epub 2026 Aug 20
Authors: Yao Z, Wei Y, Xie W, Gao R, Zhan Y, Wu X, Zhang W, Pei Y, Zhang G, Wang Z
PubMed: 42624291
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Brain organoids in Alzheimer disease and related tauopathies: Challenges and opportunities for translational readiness.

Stem Cell Reports. 2026 Aug 20;:103051. Epub 2026 Aug 20
Authors: Guruacharya A, Hartung T, Souza Dos Reis R, Moreira NC, Attisano L, Bolognin S, Iqbal K, Rajbanshi B
PubMed: 42624102
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STINGing the brain: S-nitrosylation drives neuroinflammation in Alzheimer's disease.

Cell Chem Biol. 2026 Aug 20;33(8):1065-1067.
Authors: Pieper AA, Miller E, Khalimonchuk O, Paul BD
PubMed: 42624084
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Neurodegeneration as a dysregulation of neuroimmune crosstalk.

Cell. 2026 Aug 20;189(17):5156-5173.
Authors: Bennett FC, Hong S, Jiang N, Marazzi I
PubMed: 42624075
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Beyond inflammation: Cannabinoid receptors as metabolic checkpoints in glial reprogramming during neurodegeneration.

Int Immunopharmacol. 2026 Aug 20;188:117298. Epub 2026 Aug 20
Authors: He Y, Yi Y, Sun YZ, Sun JW, Cheng R, Lin YL, Liu MX, Zhang XL
PubMed: 42624021
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Biochemical stress markers in neurodegeneration: Insights from 3D cellular models.

Curr Opin Struct Biol. 2026 Aug 20;101:103360. Epub 2026 Aug 20
Authors: Genovese I, Laurenti D, Di Risola D, Mattioli R, Mosca L
PubMed: 42623921
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Demographic Confounding in Voice-Based Parkinson Disease Screening: Methodological Analysis of the Bridge2AI Voice Dataset.

J Med Internet Res. 2026 Aug 20;28:e95609.
Authors: Shukla S, Naliyatthaliyazchayil P, Gichoya JW, Purkayastha S
PubMed: 42623305
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Elevated neuronal TAF15 expression induces oxidative stress and anxiety-related behavioral deficits.

Cell Rep. 2026 Aug 20;45(9):117885. Epub 2026 Aug 20
Authors: Yi T, Guan H, Li J, Li W, Li B, Zhu C
PubMed: 42623241
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Brief Report: Alzheimer's Disease and Related Dementia in People With Intellectually Disability in the United States.

Am J Intellect Dev Disabil. 2026 Aug 20;:1-8. Epub 2026 Aug 20
Authors: Tewolde S, Rosenberg SB, Jimenez MP, Rubenstein E
PubMed: 42623159
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Exosome-derived biomarkers as non-invasive tools in stroke, Parkinson's disease, and Alzheimer's disease.

Metab Brain Dis. 2026 Aug 20;41(1)
Authors: Talebi A, Nabili S, Alaei M, Koohsarian P, Doostmohammadi A, Dadashpour M
PubMed: 42622974
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Adaptation and feasibility of the International Registry for Alzheimer's Disease and Other Dementias real-world datasets in old-age mental healthcare practice in China.

J Alzheimers Dis. 2026 Aug 20;:13872877261478137. Epub 2026 Aug 20
Authors: Zhang H, Lai J, Wang T, Li T, Liu S, Sun DL, Chen W, Kuang W, Li X, Zhang M, Liao Z, Xiang X, Tuerxun M, Zhang X, Zhang N, Xiao S, Jessen F, Yu E, Yu X, Wang H
PubMed: 42622822
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Explainable 3D deep learning from full-head MRI suggests scalp and skull involvement in Alzheimer's disease.

J Alzheimers Dis. 2026 Aug 20;:13872877261478312. Epub 2026 Aug 20
Authors: Ebadi Jalal M, Hamidi R, Harris B, Elmaghraby A, Friedland RP, Alzheimer's Disease Neuroimaging Initiative
PubMed: 42622811
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Pathological depositions in human disease: converging mechanisms in atherosclerosis, Alzheimer's disease, and related disorders.

Mol Biomed. 2026 Aug 20;7(1)
Authors: Ragolia L
PubMed: 42622762
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Prospective evaluation of systemic coagulation function during anti-amyloid monoclonal antibody therapy in Alzheimer's disease.

J Thromb Thrombolysis. 2026 Aug 20; Epub 2026 Aug 20
Authors: Curd BC, Tolley ND, Santo M, Foster J, Leardini-Tristão M, Jacob S, Benzon H, Ye X, Shah SJ, Supiano MA, Rondina MT, Frost NA, Campbell RA, Parks AL
PubMed: 42622760
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Correction: CTE-type tau filaments in Alzheimer's disease with co-morbid LATE-NC.

Acta Neuropathol. 2026 Aug 20;152(1)
Authors: Rana JK, Pinarbasi ES, Fernandez MG, Navratna V, Conway KS, Lieberman AP, Barmada SJ, Mosalaganti S
PubMed: 42622684
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Membrane Remodeling by α-Synuclein Emerges from Complementary Contributions of Its Structured and Disordered Domains.

J Phys Chem B. 2026 Aug 20;130(33):8349-8362.
Authors: Johnson DH, Liow JS, Kou OH, Zeno WF
PubMed: 42622271
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Amyloid-Related Imaging Abnormalities Summit Special Proceedings: Cardiovascular and Stroke Considerations for β-Amyloid Immunotherapy in Alzheimer Disease.

J Am Heart Assoc. 2026 Aug 20;:e048108. Epub 2026 Aug 20
Authors: Greenberg SM, Iadecola C, Chou SH, Cogswell PM, Elkind MS, Hicks WJ, Le C, Levine DA, Lipton R, Massimo L, Mohl SM, Seshadri S, Snyder HM, Yaffe K, Zachrison KS, ARIA Summit Working Group
PubMed: 42622140
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Pathogenic GBA1 Variants and their Interaction with the Gut-Microbiota-Brain Axis in Parkinson's Disease.

Mov Disord. 2026 Aug 20; Epub 2026 Aug 20
Authors: Dainton-Howard H, Engen P, Lawrence K, Shaikh M, Abdel-Mohsen M, Green S, Naqib A, Joshi N, Villanueva M, Kirby A, Keshavarzian A, Goetz C
PubMed: 42621775
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Redefining Parkinson's disease: microglia and systemic immunity as gateways to early therapy.

Neurodegener Dis Manag. 2026 Aug 20;:1-4. Epub 2026 Aug 20
Authors: Michelucci A, Tziortziou M, Grünewald A
PubMed: 42619493
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Astrocytic 4R-tau pathology drives aquaporin-4 (AQP4) mislocalization, glymphatic dysfunction, and neurotransmitter dysregulation in mice.

J Neurosci. 2026 Aug 19; Epub 2026 Aug 19
Authors: Lu M, Tian H, Wang J, Feng R, Meng H, Zhu L, Qin C, Zhang Y, Wang X
PubMed: 42618512
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Four-year evolution of the retinal microvasculature in an APOE ε4/ε4 cognitively normal individual.

BMJ Case Rep. 2026 Aug 19;19(8)
Authors: Patel H, Corpuz E, Liu AJ, Whitson H, Grewal D, Fekrat S
PubMed: 42618314
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AI-assisted FTIR spectroscopic profiling of exosomes: Emerging frontiers in early detection of Alzheimer's disease.

Ageing Res Rev. 2026 Aug 19;:103311. Epub 2026 Aug 19
Authors: Pei J, Perumal NC, Meng P, Long Q, Palanisamy CP
PubMed: 42617979
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Pharmacological evidence suggesting the involvement of autophagy-related signaling in the cognitive effects of neuropeptide Y in an amyloid-β-induced model of Alzheimer's disease.

Behav Brain Res. 2026 Aug 19;515:116443. Epub 2026 Aug 19
Authors: Razi P, Rashtiani S, Rostampour M, Rohampour K, Jafari A
PubMed: 42617975
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Integrated multi-omics profiling identifies a convergent gut-metabolic-immune signature in Alzheimer's disease.

Free Radic Biol Med. 2026 Aug 19;256:121-133. Epub 2026 Aug 19
Authors: Ling Z, Xu X, Cheng Y, Liu X, Ding W, Zhu Z, Wu L, Chen Y, Hu P, Xia L
PubMed: 42617705
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Disordered eating behaviors in patients with severe Alzheimer's disease: A preliminary study.

Geriatr Nurs. 2026 Aug 19;73:104267. Epub 2026 Aug 19
Authors: Li J, Kaneko F, Saita K, Okamura H
PubMed: 42617348
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Carboxyl-terminal blockade of sortilin binding enhances progranulin gene therapy in a mouse model of frontotemporal dementia.

Sci Transl Med. 2026 Aug 19;18(863):eadr9158. Epub 2026 Aug 19
Authors: Kashyap SN, Fox SN, DeNittis VR, Wilson KI, Boyle NR, Bullock M, Tadepalli AS, Miller SR, Palop JJ, Ambaw YA, Walther TC, Farese RV Jr, Murchison CF, Arrant AE, Roberson ED
PubMed: 42616842
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MAPT splicing modulators reduce 4R tau and rescue tauopathy phenotypes in human neurons and in a mouse model.

Sci Transl Med. 2026 Aug 19;18(863):eady6759. Epub 2026 Aug 19
Authors: Silva MC, Lindmeier H, Pigini P, Laughlin J, Yu Y, Morrill C, Arnold MA, Barraza SJ, Saadipour K, Dieterich M, Minnella A, Wang LI, Li W, Datta K, Zhang N, Narasimhan J, Trotta CR, Woll MG, Welch EM, Benzow K, Karanjeet K, Lotz S, Bertucci T, Temple S, Haggarty SJ, Koob M, Trimmer J, Weetall M, Morini E
PubMed: 42616837
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Algebraic Connectivity Reveals Modulated High-Order Functional Networks in Alzheimer's Disease.

IEEE J Biomed Health Inform. 2026 Aug 19;PP Epub 2026 Aug 19
Authors: Dolci G, Saglia S, Brusini L, Calhoun VD, Galazzo IB, Menegaz G
PubMed: 42616623
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SCRIB is a Shared Transcriptomic Biomarker Candidate Linking Cardioembolic Stroke and Alzheimer's Disease.

J Mol Neurosci. 2026 Aug 19;76(3)
Authors: Chen Y, Song E, Yu S, Wan S, Zheng W
PubMed: 42616318
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Bacopa monnieri and Alzheimer's disease: mechanistic convergence, cognitive outcomes and translational perspectives.

Inflammopharmacology. 2026 Aug 19; Epub 2026 Aug 19
Authors: Kumawat A, Sharma MM, Nathani S
PubMed: 42616216
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Neuroinflammatory and molecular pathways in Alzheimer's disease: mechanistic crosstalk and emerging therapeutic opportunities.

Inflammopharmacology. 2026 Aug 19; Epub 2026 Aug 19
Authors: Thakur A, Sharma R, Kumari S, Prakash D, Devi A
PubMed: 42616215
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Engineering ApoE3-Targeted NIR-Responsive Liposomes for Multimodal Inhibition of Amyloid-β Aggregation and Acetylcholinesterase Activity.

ACS Chem Neurosci. 2026 Aug 19;17(16):3094-3108.
Authors: Singh SK, Dinodiya H, Parihar S, Korupalli C, Vankayala R
PubMed: 42615643
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Bis(styryl)benzene Probes for Targeting Early-Stage Amyloid-β Aggregates in Alzheimer's Disease.

ACS Chem Neurosci. 2026 Aug 19;17(16):3109-3121.
Authors: Gutíerrez C, Mina M, An J, Bhowmik S, Xu K, Salaiza J, Chen K, El Sayed T, Mirica LM
PubMed: 42615640
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Phage Display-Derived Cyclic Peptides Target TREM2 and Modulate Microglial Responses Under Amyloid Stress.

ACS Chem Neurosci. 2026 Aug 19;17(16):3082-3093.
Authors: Fuchs N, Yuan S, Kuncewicz K, Elhamouly MA, El Gaamouch F, Gabr MT
PubMed: 42615638
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Dementia With Extensive Giant Perivascular Spaces as a Mimicker of Alzheimer Disease: A Case Report.

Alzheimer Dis Assoc Disord. 2026 Aug 19; Epub 2026 Aug 19
Authors: Netterwala A, Mathew T, Johnson A, Bhardwaj S
PubMed: 42615561
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Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease.

Adv Sci (Weinh). 2026 Aug 19;:e23043. Epub 2026 Aug 19
Authors: Li L, Tang H, Yu Q, Zhang Y, Shi B, Kong Y, Xu L, Shao J, Hu C, She L, Wang Z, Chen H, Samorodov AV, Cao G, Zhao X, Wang Y
PubMed: 42615346
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Blood Pressure Variability and Alzheimer Disease Biomarkers.

Hypertension. 2026 Aug 19; Epub 2026 Aug 19
Authors: Lohman T, Sible I, Ma Y, Pahlevan NM, Nation DA
PubMed: 42615134
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Metabolic Syndrome and Dementia Risk in Older Adults: A Narrative Review.

Kaohsiung J Med Sci. 2026 Aug 19;:e70276. Epub 2026 Aug 19
Authors: Park H, Chuansangeam M, Yang YH
PubMed: 42615112
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Atlas of Brain Aging Derived from Cortical Surface Area Changes.

J Neurosci. 2026 Aug 19;46(33)
Authors: Chen X, Yan W, Su S, Zhuang M, Wang H, Zhang S
PubMed: 42469026
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Artemisinin Attenuates Aβ1-42 Aggregation via the CaMK IV/PKA-CREB-Ace-H4 Cascade in Neuronal Cultures and 3xTg-AD Models.

Am J Chin Med. 2026 Aug 19;:1-23. Epub 2026 Aug 19
Authors: Chen Y, Ge L, Lazarovici P, Zheng W
PubMed: 42623143
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Mitochondria-Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential.

Adv Healthc Mater. 2026 Aug 19;:e71594. Epub 2026 Aug 19
Authors: Gadhave DG, Jadhav AB, Waghamode NB, Khot S, Khan R, Hole R, Dhobale SM, Aswar M, Paudel KR
PubMed: 42619255
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Utilizing routinely acquired clinical neuroimaging and electronic health record data to advance precision medicine in dementia care.

Int Rev Psychiatry. 2026 Aug 19;:1-17. Epub 2026 Aug 19
Authors: Oishi K, Adams R, Nowrangi MA, Zandi PP, Lyketsos CG
PubMed: 42619056
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Estimating the Penetrance of PRNP Mutations in Chinese Prion Disease Patients based on the Genome Databases.

Genomics Proteomics Bioinformatics. 2026 Aug 19; Epub 2026 Aug 19
Authors: A R, Jia XX, Zhou DH, Wu YZ, Wang Y, Zhang WW, Xiao K, Liang DL, Gao LP, Zhou W, Chen C, Shi Q, Dong XP
PubMed: 42619012
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EXPRESS: Following the curvature: sulcal versus gyral cortical localization of cerebral microbleeds in Cerebral Amyloid Angiopathy.

J Cereb Blood Flow Metab. 2026 Aug 19;:271678X261482016. Epub 2026 Aug 19
Authors: Schipper MR, van Harten TW, Koemans E, Goeman JJ, Wermer M, Van Osch MJ, van Walderveen MA
PubMed: 42619010
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Dual-Pathway Astrocyte Failure in Parkinson's Disease: Therapeutic Targeting of Nrf2/TFEB Suppression and cGAS-STING/Ferroptosis Activation.

Mol Neurobiol. 2026 Aug 19;63(1)
Authors: Abdelaziz AM
PubMed: 42618838
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An Icelandic pangenome reference.

Nature. 2026 Aug 19; Epub 2026 Aug 19
Authors: Holley G, Eggertsson HP, Kristmundsdottir S, Beyter D, Skuladottir AT, Moore KH, Olason PI, Gylfason A, Magnusson OT, Oddsson A, Stefansson H, Helgason A, Masson G, Sulem P, Gudbjartsson DF, Stefansson K, Halldorsson BV
PubMed: 42618781
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Cortical thickness changes precede high levels of amyloid by at least 7 years.

Nat Neurosci. 2026 Aug 19; Epub 2026 Aug 19
Authors: Roe JM, Jagust WJ, Landau SM, Harrison TM, Grydeland H, Slivka M, Alatorre-Warren JL, Garrido PF, Sørensen Ø, Grødem EO, Ward TJ, Leonardsen EH, Murphy A, Lee J, Fladby T, Bjørnerud A, Walhovd KB, Fjell AM, Vidal-Piñeiro D, Wang Y
PubMed: 42618753
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Subcellular proteomic analysis of the DDR2 interactome in a neuronal cell model exposed to Aβ42.

Biochim Biophys Acta Proteins Proteom. 2026 Aug 18;1874(6):141173. Epub 2026 Aug 18
Authors: Das R, Mukhopadhyay D
PubMed: 42612957
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Nose-to-brain delivery of a novel boronated curcuminoid via cyclodextrins: Biodistribution toward potential BNCT applications in Alzheimer's disease.

J Control Release. 2026 Aug 18;:115270. Epub 2026 Aug 18
Authors: Alberti D, Micocci S, Lanfranco A, Elkhanoufi S, Bitonto V, Piña Marcos JN, Protti N, Deagostino A, Crich SG
PubMed: 42612874
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Impact of Chub Mackerel and Quinoa Supplementation on Hepatic Lipid Composition and DHA Accumulation in 5xFAD Mice.

Biochimie. 2026 Aug 18; Epub 2026 Aug 18
Authors: Gomes-Bispo A, Dias B, Gomes R, Cardoso C, Afonso C, Lopes PA, Prates JM, Bandarra NM
PubMed: 42612864
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Regenerative medicine for neurodegenerative diseases:History, Strategies, and Clinical Advances.

Transl Res. 2026 Aug 18; Epub 2026 Aug 18
Authors: Li J, Duan H, Hao P, Zhao W, Gao Y, Yang Z, Li X
PubMed: 42612795
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Autophagy as a mechanistic link between physical exercise and Alzheimer's disease.

Neuroscience. 2026 Aug 18;614:307-317. Epub 2026 Aug 18
Authors: Yu Z, Wang Y, Yang Y
PubMed: 42612783
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Emerging molecular mechanism of neuroinflammation in Parkinson's disease: A JAK/STAT and TGFβ/SMAD signaling crosstalk.

Biochim Biophys Acta Gen Subj. 2026 Aug 18;1870(11):130989. Epub 2026 Aug 18
Authors: Purkayastha K, Roy A, Bhattacharya P, Borah A
PubMed: 42612757
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The nutrition-sleep-circadian axis in age-related neurodegeneration: Cellular mechanisms, metabolic dysfunction, and neuroprotective interventions.

Ageing Res Rev. 2026 Aug 18;121:103310. Epub 2026 Aug 18
Authors: Basha S, Mahato KK
PubMed: 42612710
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[Memory distortions in Alzheimer's disease and other dementias: an underestimated diagnostic parameter].

Fortschr Neurol Psychiatr. 2026 Aug 18; Epub 2026 Aug 18
Authors: Mliavaya T, Hofbauer L, Matthes C, Haussmann R
PubMed: 42612680
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GLP-1 receptor agonists for Alzheimer's disease: Lessons from trials and translational challenges.

Cell Rep Med. 2026 Aug 18;7(8):102918.
Authors: Stringhi R, Padovani A, Marcello E
PubMed: 42612619
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SNCA-targeted transcriptional repression therapy alleviates pathological and behavioral perturbations in a Parkinson's disease mouse model.

Neurotherapeutics. 2026 Aug 18;23(5):e01049. Epub 2026 Aug 18
Authors: O'Donovan B, Rittiner J, Upadhya S, Hodgson D, Kantor B, Chiba-Falek O
PubMed: 42612388
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The protein disulfide isomerase P4HB/PDIA1 modulates cellular and misfolded forms of the prion protein.

PLoS Pathog. 2026 Aug 18;22(8):e1014536. Epub 2026 Aug 18
Authors: Amano G, Arshad H, Patel Z, Schmitt-Ulms G, Watts JC
PubMed: 42611925
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Collaborative object handling supports autobiographical recall in Alzheimer's disease.

Memory. 2026 Aug 18;:1-14. Epub 2026 Aug 18
Authors: Maussire C, El Haj M, Emmelin E, Besnard J
PubMed: 42611811
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Nonlinear Functional Connectivity and ICA Reveal Default Mode Network Hyperconnectivity in Parkinson's Disease: A Resting-State fMRI Study.

Brain Topogr. 2026 Aug 18;39(5)
Authors: Nyatega CO, Li Q, Nie W, Ahmad F, Adamu MJ
PubMed: 42611380
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Emerging roles of granzymes in neurodegeneration and neuroinflammation: mechanistic insights and therapeutic opportunities.

Acta Neuropathol. 2026 Aug 18;152(1)
Authors: Yoo HS, Yu P, Zhou C, Hosseini A, Granville DJ, Matsubara JA
PubMed: 42611377
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Modulation Mechanisms of Transmembrane Domain Flexibility in Amyloid Precursor Protein and Notch: A Coarse-Grained Simulation Study on the Impact of Upper and Lower Leaflet Composition in Liquid-Ordered and Liquid-Disordered Ternary Bilayer Membranes.

Langmuir. 2026 Aug 18;42(32):23197-23215.
Authors: Ahmad S, Mei J, Wang C, Jia M, Nouman MF, Ai H
PubMed: 42611282
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The locus coeruleus gateway hypothesis: Noradrenergic integrity as a candidate determinant of amyloid-β clearance efficiency in anti-amyloid immunotherapy for Alzheimer's disease.

J Alzheimers Dis. 2026 Aug 18;:13872877261474020. Epub 2026 Aug 18
Authors: Dodart CA
PubMed: 42611034
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Non-invasive brain stimulation increases default mode network functional connectivity in a patient with Posterior Cortical Atrophy.

Int Rev Psychiatry. 2026 Aug 18;:1-11. Epub 2026 Aug 18
Authors: Paranhos T, Du A, Eckbo R, Wong B, Camprodon JA, Dickerson BC, Eldaief M, Touroutoglou A
PubMed: 42610835
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Midlife physical activity and late-life subjective cognitive complaints in women.

Gerontologist. 2026 Aug 18; Epub 2026 Aug 18
Authors: Song Y, Wu F, Wong A, Clendenen TV, Koenig KL, Gu Y, Zeleniuch-Jacquotte A, Chen Y
PubMed: 42610694
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Bridging LysoPD and MitoPD: Lysosomal pH Links Two Hallmarks of Parkinson's Disease.

Mov Disord. 2026 Aug 18; Epub 2026 Aug 18
Authors: Prasad H
PubMed: 42610476
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Integrative Multi-Omics Analysis Reveals Convergent Epigenome and Transcriptome Changes in Parkinson's Disease.

Mov Disord. 2026 Aug 18; Epub 2026 Aug 18
Authors: Macchi M, Ginolhac A, Heurtaux T, Gomez-Ramos B, Sinkkonen L, Glaab E, NCER‐PD Consortium
PubMed: 42610474
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Quantification of practice effects in a self-administered online cognitive pre-screening test.

Neurol Sci. 2026 Aug 18;47(9)
Authors: Wischmann HA, Huijbers W, Gillies M, Nasreddine Z
PubMed: 42608601
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Acitretin-inspired medicinal chemistry for Alzheimer's disease: A biomarker-gated central nervous system (CNS) discovery framework.

Drug Discov Ther. 2026 Aug 18; Epub 2026 Aug 18
Authors: Qin TG, Han Y
PubMed: 42618229
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Epidemiology, Patient Characteristics, Treatment Patterns, and Costs of Mild Cognitive Impairment and Alzheimer's Disease in Taiwan.

Value Health Reg Issues. 2026 Aug 18;:101687. Epub 2026 Aug 18
Authors: Hu CJ, Huang YH, Cho S, Wang BC, Shen SP, Newson RS, Tang CH
PubMed: 42615950
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PCSK9 inhibitors in neurodegenerative disorders: mechanisms, therapeutic potential, and clinical implications.

Transl Neurodegener. 2026 Aug 18;15(1)
Authors: Wang JD, Teo AY, Xiao B, Chao Y, Zhou ZD, Tan BJ, Chan LL, Rosalie E, Tan EK
PubMed: 42613642
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Advances in the clinical application of mesenchymal stem cells for neurological disorders.

Stem Cell Res Ther. 2026 Aug 18;17(1)
Authors: Jamali MC, Shafie A, Alqahtani AJ, Al-Samawi RI, Alyami HM, Ashour AA, Felemban MF, Mansuri N, Tayeb FJ, Ahmad I, Mudhafar M, Sheweita SA
PubMed: 42613627
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Disease-specific tau polymorphs are associated with unique protein networks across proteinopathies.

EMBO J. 2026 Aug 18; Epub 2026 Aug 18
Authors: Puangmalai N, Bhatt N, Suthprasertporn N, Miranda-Morales EG, Shchankin N, Samples M, Balci AE, Liew JY, Montalbano M, Zhao Y, Kayed R
PubMed: 42613429
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How (We Think) Parkinson's disease begins.

Parkinsonism Relat Disord. 2026 Aug 18;:108943. Epub 2026 Aug 18
Authors: Outeiro TF, Tolosa E
PubMed: 42624662
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Mutation and oxidation of Cys46 and Cys53 allosterically modulate the glyoxalase and esterase activities of DJ-1.

Int J Biol Macromol. 2026 Aug 17;380:154089. Epub 2026 Aug 17
Authors: Xia Y, He X, Zhang Y, Wang Z, Hu R, Li Y, Zhu J, Yang Y, Liu M
PubMed: 42604680
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Editorial for "Deep Learning-Based Enhancement of Already Diagnostic-Quality MRI for Alzheimer's Disease Classification: Effects on Model Performance and Training Data Requirements".

J Magn Reson Imaging. 2026 Aug 17; Epub 2026 Aug 17
Authors: Chakraborty P
PubMed: 42608377
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Tau-targeting pharmacological strategies in neurodegenerative disease.

Trends Pharmacol Sci. 2026 Aug 17; Epub 2026 Aug 17
Authors: Zheng H, Zheng J
PubMed: 42608285
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Pathological α-synuclein propagation via the gut-liver axis induces liver injury in gut-origin Parkinson's disease mouse models.

Exp Neurol. 2026 Aug 17;406:115965. Epub 2026 Aug 17
Authors: Hu R, Wu J, Song YZ, Tao Y, Tan LL, Ma XY, Xia YM, Nie X, Li T, Li MA, Yao L, Huang SB, Jia XB, Qiao CM, Zhao WJ, Cui C, Shen YQ
PubMed: 42607920
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Annexin A1 inhibits neuronal apoptosis in amyotrophic lateral sclerosis by restraining the Hippo pathway.

Brain Res. 2026 Aug 17;1891:150510. Epub 2026 Aug 17
Authors: Zhang Y, Dong X, Shai Y, Alam M, Han D, Hu Y, He Z, Zhou Z, Jiang H
PubMed: 42607915
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Oral Administration of Melatonin Modulates Macrophage Polarization via Modulating the Vegf Signaling Pathway and Ameliorates Alzheimer's Disease in APP/PS1 Mice.

Brain Res Bull. 2026 Aug 17;:112088. Epub 2026 Aug 17
Authors: Li X, Chen Z, Guan J, Yu H, Wang J
PubMed: 42607896
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Comment on "Nutritional Interventions for Preventing Cognitive Decline in Patients with Mild Cognitive Impairment and Alzheimer's Disease: A Comprehensive Network Meta-Analysis and Mendelian Randomization Study".

Clin Nutr ESPEN. 2026 Aug 17;:105030. Epub 2026 Aug 17
Authors: Indumathi J, Arulappan A, Ramasamy S
PubMed: 42607758
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PrPC limits APP delivery to the plasma membrane and alters its processing to facilitate aβ release.

Neurobiol Dis. 2026 Aug 17;:107576. Epub 2026 Aug 17
Authors: Mehta N, Jo S, Smirnou S, Thinakaran G, Mastrianni JA
PubMed: 42607731
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Aquaporin-4 Mediated Glymphatic Dysfunction and Neuroinflammatory Signaling in Neurodegenerative Disorders.

Int J Neurosci. 2026 Aug 17;:1-29. Epub 2026 Aug 17
Authors: Singh B, Singh S, Banerjee S, Bhargava S, Subramaniyan V, Singh TG
PubMed: 42606899
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Regenerative strategies for ALS: stem cells and extracellular vesicles.

Discov Nano. 2026 Aug 17;21(1)
Authors: Raghunathan T, Parthasarathy B, Prabhu P, Mahesh P, Dhanushkodi A
PubMed: 42606797
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Mechanisms and Therapeutic Potential of Targeting Mitophagy in Neurodegenerative Diseases.

Mol Neurobiol. 2026 Aug 17;63(1)
Authors: Wang YN, Wang X, Huang Q, Yang Y, Wang T, Qu XH, Han XJ
PubMed: 42606666
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Elevated MicroRNA-146a in Alzheimer's Disease and Its Diagnostic Potential.

Mol Neurobiol. 2026 Aug 17;63(1)
Authors: Mansor MR
PubMed: 42606643
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miR-584-5p suppresses Aβ1-42-induced apoptosis in Alzheimer's disease cell model via targeting of HDAC1.

Acta Neurol Belg. 2026 Aug 17; Epub 2026 Aug 17
Authors: Cheng L, Gong P, Su X, Fang Y, Wang T
PubMed: 42606634
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Impact of stroke on respiratory function and amyloid-β pathology in Tg-2576 mice.

J Alzheimers Dis. 2026 Aug 17;:13872877261476022. Epub 2026 Aug 17
Authors: Zhang YX, El Hamamy A, Iqbal Z, Ranjan A, Sumani D, De Souza KA, Lee J, Marrelli S, McCullough LD, Li J
PubMed: 42606297
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Relationship between body composition and mortality in older patients with mild cognitive impairment and Alzheimer's disease: NCGG-STORIES.

J Alzheimers Dis. 2026 Aug 17;:13872877261476079. Epub 2026 Aug 17
Authors: Uchida K, Sugimoto T, Nakagawa T, Noguchi T, Komatsu A, Ono R, Yokoyama Y, Onoyama A, Sakurai T, Saito T
PubMed: 42606290
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AI-designed prion-capping proteins provide evidence that prion fibril ends are replication-competent surfaces that contribute to prion seeding activity and infectivity.

mBio. 2026 Aug 17;:e0083126. Epub 2026 Aug 17
Authors: Slota JA, Kirby M, Van Den Driessche A, Kielich DM, Lamoureux L, Beniac DR, Layne C, Poirier M, Stetefeld J, Booth SA, Bailey-Elkin BA
PubMed: 42606210
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Population-Level Nucleotide Diversity and Genetic Differentiation at SOD1 Across Global Human Populations.

Ann Hum Genet. 2026 Aug 17; Epub 2026 Aug 17
Authors: Flores SV, Lillo P, Briceño-Moya J
PubMed: 42606140
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TAB2 Causes Neuronal Damage by Aggravating Microglia-Mediated Neuroinflammation in Parkinson's Disease.

Adv Sci (Weinh). 2026 Aug 17;:e77175. Epub 2026 Aug 17
Authors: Zhao Y, Huang Z, Gao J, Li A, Wang H, Chen Y, Zhu G, Zhang X, Jiang Y, Zhang M, Meng F, Zhang J, Du T
PubMed: 42606072
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Clioquinol-Loaded UiO-66(Ce) Metal-Organic Frameworks for Dual Reactive Oxygen Species Scavenging and Metal Chelation in Alzheimer's Disease.

ACS Appl Bio Mater. 2026 Aug 17;9(16):7629-7636.
Authors: Subramanian L, Wu CY, Bai WZ, Lin YC, Wu KC, Chung RJ
PubMed: 42606055
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Cholinesterase inhibitors and sexual disinhibition in dementia: a FAERS disproportionality study.

Naunyn Schmiedebergs Arch Pharmacol. 2026 Aug 17; Epub 2026 Aug 17
Authors: Sayion K
PubMed: 42604874
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The mitophagy-inflammasome axis: a shared pathological hub in Alzheimer's and Parkinson's diseases.

Transl Neurodegener. 2026 Aug 17;15(1)
Authors: Long W, Yuan M, Wang S, Tan X, Gao LC
PubMed: 42608731
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Transcriptome-wide association analysis of Alzheimer's disease: construction and clinical validation of transcriptomic risk scores.

Eur Arch Psychiatry Clin Neurosci. 2026 Aug 17; Epub 2026 Aug 17
Authors: Zhang PF, Juan Z, Han J, Wang Y, Zhu T, Pang D, Zheng X, Lu Z
PubMed: 42608584
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Diagnostic accuracy of a self-administered digital cognitive test battery for differentiating early Alzheimer's disease from controls.

Eur Arch Psychiatry Clin Neurosci. 2026 Aug 17; Epub 2026 Aug 17
Authors: Rutt S, Tegethoff P, Taute M, Neziraj F, Hufnagel A, Perneczky R, Kurz C, Rauchmann BS
PubMed: 42608580
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Oxyberberine-nanoparticle attenuates the cognitive deficits in a transgenic mouse model of Alzheimer's disease via modulating gut microbiota through suppressing CXCL10/CXCR3 pathway.

Acta Pharmacol Sin. 2026 Aug 17; Epub 2026 Aug 17
Authors: Wu YL, Xu QQ, Qin ZH, Wu X, Hu Z, Yang W, Ren PY, Tian YY, Lin ZX, Xian YF
PubMed: 42608531
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Combined impact of depressive symptoms and mild cognitive impairment on Parkinson's disease progression.

Parkinsonism Relat Disord. 2026 Aug 17;151:108944. Epub 2026 Aug 17
Authors: Hu T, Xu C, Tang Y, Xu Z, Li X, Liang X, Wang J, Han L, Li S
PubMed: 42624056
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Periodontal Status and the Risk of All-Cause Dementia, Alzheimer's Disease and Vascular Dementia in a Community: The Hisayama Study.

J Clin Periodontol. 2026 Aug 16; Epub 2026 Aug 16
Authors: Furuta M, Ohara T, Sakata S, Shibata M, Oishi E, Furuta Y, Kageyama S, Asakawa M, Shimazaki Y, Takeshita T, Ninomiya T
PubMed: 42604767
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Translational Paradox of Triplet Repeat Expansion Disorders: Synthesizing Clinical Trial Failures to Guide Future Therapeutics.

Clin Pharmacol Ther. 2026 Aug 16; Epub 2026 Aug 16
Authors: Swarup V, Deepika D, Garg D, Srivastava AK
PubMed: 42605151
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Comment on 'Predicting cognitive function in Alzheimer's clinical trials via amyloid β-protein biomarkers'.

Br J Clin Pharmacol. 2026 Aug 16; Epub 2026 Aug 16
Authors: Wang J
PubMed: 42605141
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Those Debating Alzheimer Disease Modifying Therapies Should Review the Seminal JAGS Dementia Minimal Clinically Important Difference Article.

J Am Geriatr Soc. 2026 Aug 16; Epub 2026 Aug 16
Authors: Molnar FJ
PubMed: 42604943
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Corrigendum to "Sensory decline in aging and neurodegeneration: A mitochondrial perspective" [Pharmacol. Res., 2026 230 108322].

Pharmacol Res. 2026 Aug 15;:108385. Epub 2026 Aug 15
Authors: Adeboye O, Gonda BL, Gulati N, Hu K, Karp AR, McNally DC, Tsai W, Zarate JG, Holmes M, Johnson-Kleinpeter L, Kwok HY, Miranda VJ, Nguyen JH, Patel KA, Polagoni A, Ramirez B, Da Costa RT, Love CR, Grigoriev A, Solesio ME
PubMed: 42603745
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Restoration of Neuronal Metabolism and Memory in Alzheimer's Disease by Reprogramming the Exosomal microRNA Network.

J Mol Neurosci. 2026 Aug 15;76(3)
Authors: Anwer T, Verma A, Asiri A, Alaklobie M, Albaqami A, Alshahrani F, Aly K, Sharma M, Siddiqui S, Alam N, Alam MF
PubMed: 42603243
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Distinct alpha-synuclein seeding in post-mortem skin of Lewy body disease and multiple system atrophy.

Acta Neuropathol. 2026 Aug 15;152(1)
Authors: Kim A, Abkur T, Enomoto M, Xu X, Lang AE, Tartaglia C, Kovacs GG, Martinez-Valbuena I
PubMed: 42603223
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Epigenomic priming of microglia bridges psychopathology and late-life cognitive decline.

Neuropsychopharmacology. 2026 Aug 15; Epub 2026 Aug 15
Authors: To A, Girgenti MJ
PubMed: 42603812
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Deep learning-driven discovery and optimization of natural LSD1 inhibitors for the treatment of Alzheimer's disease.

Bioorg Chem. 2026 Aug 15;181:110396. Epub 2026 Aug 15
Authors: Li Z, Sun T, Han M, Xiao B, Liu S, Zhang J, Ma J, Ma H, Yang J, Zhang Z
PubMed: 42612268
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cis-γ-Amino-L-proline peptides as chemical probes of amyloidogenic processing in neurons and APP/PS1 mice.

Bioorg Chem. 2026 Aug 15;181:110386. Epub 2026 Aug 15
Authors: Jácome D, Pérez-Palau M, Martínez-Soria I, Lidón L, Vergara C, Carbajo D, Pulido X, Sánchez-Navarro M, Giralt E, Albericio F, Royo M, Gavín R, Del Río JA
PubMed: 42617419
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Iatrogenic cerebral amyloid angiopathy: a scoping review.

J Neurol Neurosurg Psychiatry. 2026 Aug 14; Epub 2026 Aug 14
Authors: Ikeda S, Hamaguchi T, Hirano T, Yagita Y, Koga M, Ihara M, Nakajima M, Itabashi R, Shindo A, Kudo K, Saito N, Sekijima Y, Kouda K, Murakami A, Inutsuka R, Sekiguchi K, Kosami K, Ae R, Ono K, Fujimoto S, Yakushiji Y
PubMed: 42601217
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Verb-Semantic Feature Analysis for Alzheimer's Dementia in a verb-final language: evidence from Korean.

Neuropsychol Rehabil. 2026 Aug 14;:1-25. Epub 2026 Aug 14
Authors: Koh H, Choi S, Sung JE
PubMed: 42601176
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Hippocampal Klotho expression is associated with the neuroprotective effects of metformin against ICV-STZ-induced cognitive deficits.

Eur J Pharmacol. 2026 Aug 14;1032:179245. Epub 2026 Aug 14
Authors: Shanehbandpour-Tabari F, Golchoobian R, Pourabdolhossein F
PubMed: 42601004
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Circular RNAs in amyotrophic lateral sclerosis.

Neurobiol Dis. 2026 Aug 14;228:107574. Epub 2026 Aug 14
Authors: Ataei R, Amini J, Sanadgol N, Simon AF, Duennwald ML
PubMed: 42600995
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Multiple system atrophy-derived α-synuclein fibrils are more potent and display oligodendrocyte cell tropism compared to Parkinson's disease-derived fibrils.

Neurobiol Dis. 2026 Aug 14;228:107575. Epub 2026 Aug 14
Authors: Laursen AS, Willén K, Fenyi A, Volbracht C, Dalgaard LT, Aznar S, Melki R, Fog K, Sotty F
PubMed: 42600994
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Identifying candidate therapeutic targets in amyotrophic lateral sclerosis through a transcriptome-wide machine-learning consensus approach for drug repurposing.

Neuroscience. 2026 Aug 14;614:163-179. Epub 2026 Aug 14
Authors: deAndrés-Galiana EJ, Fernández-Martínez JL, Morís G
PubMed: 42600917
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Pyroptosis in Alzheimer's disease: Mechanisms and neuroinflammatory networks.

Mol Cell Neurosci. 2026 Aug 14;138:104113. Epub 2026 Aug 14
Authors: Wu X, Ye Q, Zi M, Jiang H, Meng S, Zheng J, Zeng S, Ma C, Hu X, Zhao B, Li H
PubMed: 42600903
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Allosteric modulation of ionotropic and G protein-coupled receptors in Alzheimer's disease: A neuroprotective strategy and therapeutic implications.

Int J Biol Macromol. 2026 Aug 14;379:154063. Epub 2026 Aug 14
Authors: Fereidouni A, Nematollahi S, Mathew KT, Favennec V, Liceran L, Aldenhoff-Kelly C, Valdivieso MA, Trent S, Moradikor N
PubMed: 42600807
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Small nucleolar RNAs: Emerging therapeutic and diagnostic frontiers in Alzheimer's disease.

Drug Discov Today. 2026 Aug 14;:104771. Epub 2026 Aug 14
Authors: Sharma T, Sharma P, Bashir B, Singh SK, Vishwas S
PubMed: 42600734
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Sex composition as an unaddressed confound in FDG-PET predictive models of Alzheimer's disease conversion.

J Nutr Health Aging. 2026 Aug 14;30(10):100955. Epub 2026 Aug 14
Authors: Rudroff T
PubMed: 42600372
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ATF4 activates a transcriptional program that chronically suppresses mTOR activity and promotes neurodegeneration in Parkinson disease models.

Cell Rep. 2026 Aug 14;45(8):117832. Epub 2026 Aug 14
Authors: Demmings MD, Kane EA, Tennyson EC, Hurley K, Zhao J, Cruickshanks NA, Ciz V, Krupa JM, Pasternak SH, Cregan SP
PubMed: 42599806
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TTN+ macrophages are enriched in the human choroid plexus in Alzheimer's disease.

Cell Rep. 2026 Aug 14;45(8):117859. Epub 2026 Aug 14
Authors: Bhatta S, Grzybowski A, Ortiz G, DiStasio M
PubMed: 42599802
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Prevalence, predictors, and emerging biomarkers for cognitive impairment and neuropsychiatric manifestations in Parkinson's disease in Africa: A systematic review.

J Parkinsons Dis. 2026 Aug 14;:1877718X261479269. Epub 2026 Aug 14
Authors: Njohjam MN, Niakam FT, Ngoule MO
PubMed: 42599715
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The case for FDG-PET and NaF-PET in risk stratification of mild cognitive impairment.

J Alzheimers Dis. 2026 Aug 14;:13872877261477750. Epub 2026 Aug 14
Authors: Alavi A, Gujral J, Gandhi OH, Amanullah AA, Ayubcha C, Patil S, Werner TJ, Høilund-Carlsen PF
PubMed: 42599695
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Cerebrospinal fluid glial cell line-derived neurotrophic factor levels interact with APOE ε4 genotype to influence cognitive decline in older adults without dementia.

J Alzheimers Dis. 2026 Aug 14;:13872877261477047. Epub 2026 Aug 14
Authors: Wang S, Zou S, Alzheimer's Disease Neuroimaging Initiative
PubMed: 42599691
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Multimodal MRI insights into hippocampal pathological changes across the Alzheimer's disease continuum: advances and challenges.

Jpn J Radiol. 2026 Aug 14; Epub 2026 Aug 14
Authors: Wang Y, Gu Z, Zhang H, Bi X, Chen L, Lu J
PubMed: 42599667
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Astrocytes orchestrate neuroprotection and pathogenesis via bidirectional neuronal interactions in Parkinson's disease.

J Physiol Biochem. 2026 Aug 14;82(1)
Authors: Li Y, Li Q, Wang Y, Wang X, Di G, Niu M, Xu Z, Huang Y
PubMed: 42599550
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Unravelling the phytochemical complexity of neuroprotective plants: a metabolomics approach to Alzheimer's disease.

Mol Biol Rep. 2026 Aug 14;53(1)
Authors: Raj SN, Natnan ME, Lou WP, Mediani A, Tencomnao T, Baharum SN
PubMed: 42599532
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The UNC13A cryptic exon associates with cognitive impairment in Alzheimer's disease.

Alzheimers Res Ther. 2026 Aug 14;18(1)
Authors: Reeves MM, Aviles Carpintero S, Zanovello M, Jansen-West K, Yue M, Calliari A, Song Y, Dunmore J, Maroto Cidfuentes C, Ball S, Kachergus JM, Killeen HE, Rawlinson B, Engelberg-Cook E, DeTure M, Day GS, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Murray M, Thompson AE, Dickson DW, Fratta P, Petrucelli L, Josephs KA, Prudencio M
PubMed: 42596024
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α-Synuclein strain homogeneity in multiple system atrophy subtypes.

Brain Pathol. 2026 Aug 14;:e70134. Epub 2026 Aug 14
Authors: Lau HH, Silver NR, Mehra S, So RW, Li LY, Mao A, Stuart E, Schmitt-Ulms C, Hyman BT, Ingelsson M, Watts JC
PubMed: 42601815
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Gut microbiota alterations and their correlation with constipation in older adults with Alzheimer's disease or mild cognitive impairment: A cross-sectional study.

Medicine (Baltimore). 2026 Aug 14;105(33):e50227.
Authors: Huang KY, Wei YY, Zhang ST, He LC, Zhou J, Zhou LS, Su HB, Lu GD
PubMed: 42601718
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Association between habitual sleep duration and Alzheimer's disease: A cross-sectional study based on NHANES 2007-2018.

Medicine (Baltimore). 2026 Aug 14;105(33):e50086.
Authors: Yang G, Hou W, Wu J, Yang X, Yang Y, Chen Q, Liu Y
PubMed: 42601701
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Cross-Sectional and Longitudinal Diagnostic Performance of Plasma p-tau217 and p-tau217/Aβ42 in Alzheimer's Disease.

Ann Neurol. 2026 Aug 14; Epub 2026 Aug 14
Authors: Jiang M, Lan G, Zhu J, Zhang L, Li A, He Z, Zhu Y, Zhou X, Liang L, Gao N, Sun P, Cai Y, Fan X, Chen X, Shi D, Liu Z, Wang Q, Cheng G, Wang L, Alzheimer's Disease Neuroimaging Initiative, Dong M, Wang YJ, Guo T
PubMed: 42601653
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Amplification of seeding-competent tau aggregates by PMCA in human and experimental tauopathies.

Acta Neuropathol Commun. 2026 Aug 14;14(1)
Authors: Almela F, Belondrade M, Caillierez R, Leclercq S, Bouillet T, Bégard S, Oosterlynck M, Eddarkaoui S, Boluda S, Buée L, Nicot S, Colin M, Bougard D
PubMed: 42601641
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Regulation and roles of mammalian mitophagy.

Nat Rev Mol Cell Biol. 2026 Aug 14; Epub 2026 Aug 14
Authors: Martens S, Ganley IG
PubMed: 42601490
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PLCG2 downregulation impairs synaptic function and increases Alzheimer's disease hallmarks in neuronal cultures.

Nat Genet. 2026 Aug 14; Epub 2026 Aug 14
Authors: Coulon A, Rabiller F, Takalo M, Roy A, Pelletier A, Martiskainen H, Siedlecki-Wullich D, Lannette-Weimann N, Majerníková N, Grenon A, Gao V, Erhardt A, Pernodet A, Lemaire M, Limoge F, Walle P, Mendes T, Guyot K, Lemeu C, Carvalho LI, Melo de Farias AR, Hulsman M, Najdek C, Freire-Regatillo A, Saha O, Amouyel P, Charbonnier C, Deleuze JF, Dols-Icardo O, Jeskanen H, Willman RM, Kuulasmaa T, Kurki M, Hardy J, Heikkinen S, Holstege H, Mäkinen P, Nicolas G, Mead S, Wagner M, Ramirez A, Rauramaa T, Palotie A, Sims R, Soininen H, van Swieten J, Williams J, Bellenguez C, Gelle C, Lambert E, Costa MR, Tcw J, Glaab E, Ayral AM, Demiautte F, Grenier-Boley B, Muntaner M, Eberlé D, Deforges S, Haas JT, Kilinc D, Mulle C, Chapuis J, Hiltunen M, Dumont J, Lambert JC
PubMed: 42601455
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A self-powered photoelectrochemical sensor with ultra-low background based on ZnIn2S4@CdS photoanode and Bi2WO6 photocathode for BACE1 detection.

Biosens Bioelectron. 2026 Aug 14;313:119128. Epub 2026 Aug 14
Authors: Xu A, Zheng H, Kong Z, Wang X, Dong H, Lv Y, Xu M, Zhou Y
PubMed: 42607409
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Vitamin D receptor FokI polymorphism preferentially modulates cognitive vulnerability in Parkinson's disease: Evidence from an Indian cohort.

J Neuroimmunol. 2026 Aug 14;421:579072. Epub 2026 Aug 14
Authors: Pal R, Das N, Kumar H, Dey S, Choudhury S, Basu BR
PubMed: 42612512
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Sleep-wake control with age and neurodegenerative diseases.

Sleep Med Rev. 2026 Aug 14;90:102352. Epub 2026 Aug 14
Authors: Tang WX, Yang C, Zhang M, Kushida CA, de Lecea L, Li SB
PubMed: 42617572
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A Niacin-α-Lipoic Acid Hybrid Ameliorates Alzheimer's Disease Pathology in Mouse Models.

ACS Pharmacol Transl Sci. 2026 Aug 14;9(8):2250-2265. Epub 2026 Jul 20
Authors: Peng W, Wei C, Liu J, Pi J, Ding C, Guo H, Chen X, Lu J, Liu R, Yin W, Zhang G, Tsim KW, Pi R
PubMed: 42614901
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The Substrate-Engine Model of Ferroptosis: Stage-Specific Targeting of Acyl-CoA Synthetase Long-Chain Family Member 4 and 5‑Lipoxygenase in Alzheimer's Disease.

ACS Pharmacol Transl Sci. 2026 Aug 14;9(8):2044-2075. Epub 2026 Aug 4
Authors: Mondal A, Acharya R, Jain S
PubMed: 42614881
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Protease-Mediated TAR DNA-Binding Protein 43 (TDP-43) Pathogenesis: From Molecular Mechanisms to Therapeutic Opportunities.

ACS Pharmacol Transl Sci. 2026 Aug 14;9(8):2076-2091. Epub 2026 Jul 16
Authors: Xavier J, Singh M, Tamhankar S, Griffett K, Amin R
PubMed: 42614660
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Translational imaging evidence for rapid reversal of amyloid and myelin pathology following deep cervical lymphatic-venous anastomosis in Alzheimer's disease.

Nucl Med Biol. 2026 Aug 14;160-161:109675. Epub 2026 Aug 14
Authors: Wang X, Liu Y, Liu J, Wang R, Zheng J, Deng Z, Song K, Zhang D, Wang C, Zhu K, Zhang J, Wu C, Hou G, de Vries EF, Wang Y
PubMed: 42623762
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Apathy in Lewy Body Disorders: A Position Paper.

Mov Disord. 2026 Aug 13; Epub 2026 Aug 13
Authors: Kulisevsky J, Bojtos L, Kramberger MG, Mantovani E, Murasan I, Palma JA, Poplawska-Domaszewicz K, Sauerbier A, Chaudhury KR, Odin P, Weintraub D, Schrag A, Falup-Pecorariu C
PubMed: 42596621
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Comparison of Claims-Based Algorithms for Dementia Identification: A Cross-Sectional Analysis of the National Health and Aging Trends Study (NHATS).

J Am Geriatr Soc. 2026 Aug 13; Epub 2026 Aug 13
Authors: Gupta R, Charankevich H, Drabo EF, Brown T, Gross AL, Polsky D, Segal JB, Ornstein KA
PubMed: 42596083
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Editorial for "Structural Magnetic Resonance Imaging Volumetry Index for Differentiation of Progressive Supranuclear Palsy From Parkinson's Disease, and Multiple System Atrophy by Automatic Segmentation, A Comparison With Magnetic Resonance Parkinsonism Index".

J Magn Reson Imaging. 2026 Aug 13; Epub 2026 Aug 13
Authors: Benitez S, Dehkharghani S
PubMed: 42596062
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Dendritic translation and neuroproteasome-mediated degradation of endogenous tau revealed by STARFISH.

Nat Neurosci. 2026 Aug 13; Epub 2026 Aug 13
Authors: Konrad-Vicario KD, Paradise V, Demir LY, Nguyen C, Makinson CD, Ming Z, Ramachandran KV
PubMed: 42595893
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Correction: The proapoptotic BCL-2 family member BIM mediates motoneuron loss in a model of amyotrophic lateral sclerosis.

Cell Death Differ. 2026 Aug 13; Epub 2026 Aug 13
Authors: Hetz C, Thielen P, Fisher J, Pasinelli P, Brown RH, Korsmeyer S, Glimcher L
PubMed: 42595782
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Generation of a human induced pluripotent stem cell line (HEBHMUi019-A) from a 67-year-old male Alzheimer's patient with APOE-ε4/ε4 genotype.

Stem Cell Res. 2026 Aug 13;95:104082. Epub 2026 Aug 13
Authors: Ma J, Hua Z, Zhao B, Xu J, Bao K, Guo R
PubMed: 42603521
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Inhibition of mitochondrial complex III causes selective dopaminergic neurotoxicity by redox stress in Caenorhabditis elegans.

Redox Biol. 2026 Aug 13;96:104351. Epub 2026 Aug 13
Authors: Huayta J, Webster AS, Jhaver J, Meyer JN
PubMed: 42607498
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Novel Compounds as TREM2 Agonists for Treating Parkinson's Disease, Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, Nasu-Hakola Disease, and Stroke.

ACS Med Chem Lett. 2026 Aug 13;17(8):1723-1724. Epub 2026 Jul 3
Authors: Sabnis RW, Sabnis AR
PubMed: 42621473
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From 18F‑MC225 to Conformationally Free Derivatives.

ACS Omega. 2026 Aug 11;11(31):45949-45963. Epub 2026 Jul 29
Authors: Lisi AT, Mastropasqua F, Abate C, Contino M, Perrone MG, Graziano G, Carrieri A, Colabufo NA, Filosa C, Calcagni ML, Giordano A, Di Giuda D
PubMed: 42597856
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Kaempferol attenuates microglial activation in Alzheimer's disease via inhibiting the cytosolic HK2-mediated NF-κB signaling pathway.

Phytomedicine. 2026 Aug 11;160:158708. Epub 2026 Aug 11
Authors: Wang M, Guo M, Li S, Song L, Wu M, Zhao J, Xu T, Zhou Y
PubMed: 42603526
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Recent developments in donepezil-based hybrid molecules as multi-target therapeutics for Alzheimer's disease: A paradigm shift beyond symptomatic treatment.

Bioorg Chem. 2026 Aug 10;181:110361. Epub 2026 Aug 10
Authors: Kumar N, Khan I, Singh J, Kumar K, Kushwaha VK, Ojha S, Raman SK, Shankar G
PubMed: 42600466
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Barriers and Facilitators to the Inclusion of Sex- and Gender-Based Analyses in Neurodegeneration in Aging Research.

Can J Neurol Sci. 2026 Aug 10;:1-21. Epub 2026 Aug 10
Authors: Wu P, Galea LA, Einstein G, Goodarzi Z
PubMed: 42572268
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Generation of mutant human SOD1 knock-in mouse lines at the Rosa26 locus as a platform for developing genome-editing therapies for amyotrophic lateral sclerosis.

Exp Anim. 2026 Aug 8; Epub 2026 Aug 8
Authors: Okunomiya T, Sakasai T, Tsukita K, Shimizu R, Okusa A, Adachi M, Tomita S, Tanaka A, Kondo T, Imamura K, Inoue H
PubMed: 42572287
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Editor's View - Blood-based markers for diagnosis of Alzheimer's disease.

Age Ageing. 2026 Aug 3;55(8)
Authors: Soiza RL
PubMed: 42613670
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A plasma-based protein signature combining NPTXR, ACHE, and p-tau217 predicts progression to symptomatic Alzheimer's disease.

Alzheimers Dement. 2026 Aug;22(8):e71748.
Authors: Liu M, Gong K, Chen Y, Heo G, Xu Y, Timsina J, Western D, Budde J, Morris JC, Marco G, Holtzman DM, Hinson J, Levin S, Ashton N, Denkinger M, Schindler SE, Das K, Ali M, Cruchaga C
PubMed: 42598783
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Regional astrocyte dysregulation and altered glymphatic-related markers in Alzheimer's disease frontal cortex.

Alzheimers Dement. 2026 Aug;22(8):e71745.
Authors: Alexopoulos H, Louka XP, De Natale ER, Koutroubi K, Cashmore L, Panayotacopoulou MT, Trougakos IP, Wilson H, Politis M
PubMed: 42598755
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Volume change with gantenerumab: Impact of amyloid-related imaging abnormalities and amyloid removal.

Alzheimers Dement. 2026 Aug;22(8):e71749.
Authors: Tonietto M, Silvestri E, Belder CR, Barkhof F, Fox NC, Smith J, Klein G
PubMed: 42598748
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Gut-brain axis dysregulation in Parkinson's disease: Mechanisms linking microbiota to neuroinflammation and α-synuclein pathology.

J Pharm Anal. 2026 Aug;16(8):101521. Epub 2025 Dec 11
Authors: Zhao Z, Dong M, Mu Z, Zheng Z, Zhang Z
PubMed: 42598050
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A Novel Nogo-A Receptor Antagonist Peptide Impedes Alzheimer's Disease Pathology by Nogo-A/NgR/ROCK Signaling Pathway.

CNS Neurosci Ther. 2026 Aug;32(8):e71052.
Authors: Zhang Z, Tan H, Shi F, Dai J, Ding W, Li J, Wang Y, Yang R, Xu X, Chen C, Xiao F, Huang LA, Liu X, Liao R, Yan L
PubMed: 42596624
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Rising Comorbid Alzheimer's and Hypertension Mortality in Older Adults in the United States: Trends and Disparities From a 21-Year CDC WONDER Analysis (1999-2019).

J Clin Hypertens (Greenwich). 2026 Aug;28(8):e70348.
Authors: Kaleem M, Raza A, Kalpina FN, Fatima M, Batool SJ, Haider B, Rashid H, Jamal M, Turkmani M, Khan U
PubMed: 42603781
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The Japanese Translation Study of the Cognitive Reserve Index Questionnaire.

Geriatr Gerontol Int. 2026 Aug;26(8):e70803.
Authors: Katayama O, Yamaguchi R, Yamagiwa D, Akaida S, Shimoda T, Nakajima C, Kawakami A, Harada K, Nakakubo S, Sakimoto F, Matsuda S, Nishijima C, Nosaka S, Abe K, Morikawa M, Kakita D, Okuya T, Soma K, Hirano Y, Nakashima Y, Shimada H
PubMed: 42608316
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Exercise and Circadian Rhythm Regulation: Mechanisms, Resilience, and Therapeutic Potential for Neurological Diseases.

CNS Neurosci Ther. 2026 Aug;32(8):e71035.
Authors: Demura M, Gregory P, Fukuda N, Lo EH, Arai K
PubMed: 42605248
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Gantenerumab for Early Alzheimer's Disease: An Updated Systematic Review and Meta-Analysis.

Brain Behav. 2026 Aug;16(8):e71643.
Authors: Javed MN, Khan SM, Mustafa S, Mujtaba A, Amin H, Azhar N, Hameed A, Zayed A, Khalid M, Hussain JM
PubMed: 42605139
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Generalized plaque digitization framework for multi-dimensional mesoscopic images.

Biomed Opt Express. 2026 Aug 1;17(8):4198-4215. Epub 2026 Jul 20
Authors: Gong G, Liu X, Jia X, Long B, Chen S, Jiang T, Luo Y, Feng Z, Li X, Luo Q, Gong H, Li A
PubMed: 42610137
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[Immune Checkpoint Tim-3 Regulates Microglial Function in Alzheimer's Disease].

Brain Nerve. 2026 Aug;78(8):931-937.
Authors: Kimura K
PubMed: 42609152
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[Peripheral Autonomic Neuropathy in α-Synucleinopathy].

Brain Nerve. 2026 Aug;78(8):889-892.
Authors: Yagita K, Takao M
PubMed: 42609146
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Exploring Genetic Therapies Targeting Amyotrophic Lateral Sclerosis in Animal Models: A Systematic Review and Meta-Analysis.

J Gene Med. 2026 Aug;28(8):e70106.
Authors: Wedgwood HE, Tuxworth RI, Ahmed Z
PubMed: 42609140
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Characterization of [18F]SMBT-1 binding substrates in Alzheimer's disease and related disorders: A postmortem biochemical and immunohistochemical study.

Alzheimers Dement. 2026 Aug;22(8):e71685.
Authors: Abrahamson EE, Kofler JK, Lopez OL, Cohen AD, Gogola A, Aizenstein HJ, Karikari TK, Mufson EJ, Villemange VL, Ikonomovic MD
PubMed: 42609050
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Active Vaccination Strategies for Alzheimer's Disease: An Expanded Review.

Eur J Immunol. 2026 Aug;56(8):e70250.
Authors: Comitato A, Neri A, Cossarizza A
PubMed: 42609045
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Efficacy and Evidence Certainty of High-Frequency rTMS for Cognitive Impairment Across Neuropsychiatric Disorders: An Umbrella Review.

Brain Behav. 2026 Aug;16(8):e71695.
Authors: Wu LL, Huang XC, Bi JJ, He PY
PubMed: 42608972
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Transgenic A53T Mice Have Astrocytic α-Synuclein Aggregates in Dopamine and Striatal Regions.

Neuropathol Appl Neurobiol. 2026 Aug;52(4):e70097.
Authors: Peat C, Prasad A, Finkelstein DI, Sue C, Johnston JA, Parish CL, Thompson L, Kirik D, Halliday GM
PubMed: 42608961
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SOD1 Variants in Patients With Amyotrophic Lateral Sclerosis in Central Eastern Europe: From Genetic Testing to SOD1 Targeted Therapy.

Eur J Neurol. 2026 Aug;33(8):e70717.
Authors: Khazaal M, Stretavská P, Kuźma-Kozakiewicz M, Nieporęcki K, Betík A, Vlčková E, Koprušáková MT, Petrovic R, Cetin H, Keritam O, Löscher W, Eggers C, Iglseder S, Orenčák R, Molnár MJ, Grosz Z, Szlepák T, Koritnik B, Koszewicz MA, Baumgartner D, Slachtova L
PubMed: 42615765
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Blood Biomarkers of Alzheimer's Disease and Gait Speed Trajectories in Community-Dwelling Older Adults: A Cohort Study.

J Cachexia Sarcopenia Muscle. 2026 Aug;17(4):e70365.
Authors: Leal-Martín J, Grande G, Gregorio C, Calderón-Larrañaga A, Ornago AM, Fratiglioni L, Valletta M, Fredolini C, Welmer AK, Winblad B, Vetrano DL
PubMed: 42613917
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Donanemab for early Alzheimer disease.

Aust Prescr. 2026 Aug;49(4):151-153.
Authors:
PubMed: 42621858
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Arachnoid granulation morphologies and β-amyloid and tau pathology in older adults.

Alzheimers Dement. 2026 Aug;22(8):e71736.
Authors: Mehta RI, Wang T, Lewis A, Walker CE, Gebczak C, Barnes LL, Bennett DA, Mehta RI
PubMed: 42619370
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Optimized plasma p-tau217 and p-tau217/Aβ42 cutoffs enhance detection of pre-clinical Alzheimer's disease across diverse participants.

Alzheimers Dement. 2026 Aug;22(8):e71763.
Authors: Piura YD, Aduen PA, Schecter L, Jain MK, Algeciras-Schimnich A, Figdore DJ, Bornhorst J, Petersen RC, Jr CR, Graff-Radford NR, Lachner C, Day GS
PubMed: 42619350
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Group-level versus individualized approaches for capturing tau PET changes and clinical progression in Alzheimer's disease.

Alzheimers Dement. 2026 Aug;22(8):e71718.
Authors: de Bruin H, Groot C, Zhu Z, van de Giessen E, Shcherbinin S, Kotari V, Svaldi DO, Pijnenburg YA, Coomans EM, Ossenkoppele R, Franzmeier N, Alzheimer's Disease Neuroimaging Initiative (ADNI)
PubMed: 42619345
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Clinical implementation of digital cognitive assessments - recommendations from Global CEO Initiative on Alzheimer's Disease.

Alzheimers Dement. 2026 Aug;22(8):e71767.
Authors: Tariot PN, Gitelman DR, Govia I, Partrick KA, Scholler E, Petersen M, CEOi Digital Cognitive Assessment Workgroup
PubMed: 42619326
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When myelin breaks, tau aggregates - a new perspective on Alzheimer's disease.

Alzheimers Dement. 2026 Aug;22(8):e71774.
Authors: Tiane A, van den Hove D, Vanmierlo T
PubMed: 42619321
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Menopausal insomnia as a modifiable node of dementia risk: Mechanistic insights and intervention strategies.

Alzheimers Dement. 2026 Aug;22(8):e71766.
Authors: Zhang W, Zheng X, Lian T, Wang X, Wang Y, Peng D, Huang Y, Liu S, Zheng Y, Zhang W
PubMed: 42619312
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Prospective study on physical activity and Alzheimer's disease-related biomarkers.

Alzheimers Dement. 2026 Aug;22(8):e71755.
Authors: Iso-Markku P, Tu XM, Rissman RA, Gillespie NA, Elman JA, Fennema-Notestine C, Panizzon MS, Reynolds CA, Lyons MJ, Kremen WS, Franz CE, Vietnam Era Twin Study of Aging
PubMed: 42619275
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Integrative Phytotherapy for Neurodegenerative Disorders: Bridging Traditional Botanicals, Bioactive Compounds, and Nanotechnology.

Curr Pharm Biotechnol. 2026 Jul 31; Epub 2026 Jul 31
Authors: Prajapati S, Yadav S, Singh AP, Singh K, Jain D, Gupta JK, Sharma MC
PubMed: 42613701
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Proteomic Basis of Polypharmacological Cognitive Recovery in Down Syndrome and Alzheimer's Disease.

Curr Alzheimer Res. 2026 Jul 31; Epub 2026 Jul 31
Authors: Kulan H
PubMed: 42613699
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Synergistic Role of Caffeic Acid with Conventional Neuroprotective Drugs: Potential of Combination Therapy for Managing Alzheimer's Disease.

Recent Adv Inflamm Allergy Drug Discov. 2026 Jul 31; Epub 2026 Jul 31
Authors: Sharma A, Singh P
PubMed: 42613698
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An Innovative Strategy for Treating Neurodegenerative Disorders through Exosome-based Smart Delivery Systems: A Comprehensive Review.

CNS Neurol Disord Drug Targets. 2026 Jul 31; Epub 2026 Jul 31
Authors: Abubakar MD, Dahiya R, Nama L, Goyal K, Ambawatiya A, Bishnoi M, Rai A, Murti K, Kumar N
PubMed: 42613696
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Myelin and Oligodendrocyte Dysfunction in Demyelinating and Neurodegenerative Disorders: Signaling Pathways and Therapeutic Targets.

CNS Neurol Disord Drug Targets. 2026 Jul 31; Epub 2026 Jul 31
Authors: Shukla S, Srivastava V, Gaur H, Rai A
PubMed: 42613694
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Pharmacological treatments of REM sleep behaviour disorder in synucleinopathies: a systematic review of effectiveness and safety.

Sleep Med. 2026 Jul 31;148:109154. Epub 2026 Jul 31
Authors: Byun JJ, Badrakalimuthu VR
PubMed: 42623795
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Posterior cortical atrophy with initial psychiatric presentation: a case report.

J Med Case Rep. 2026 Jul 23;20(1)
Authors: Swane V, Biering-Sørensen B
PubMed: 42608702
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Gerstmann-Straussler-Scheinker Disease With F198S Mutation Diagnosis on Repeat Genetic Testing: A Case Report.

Cureus. 2026 Jul;18(7):e112851. Epub 2026 Jul 17
Authors: Medina Garcia A, Yang W, Kingsbury C, Evans L, Zesiewicz TA
PubMed: 42605331
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Auditory Biomarkers in Neurodegenerative Disorders: A Literature Review.

J Otol. 2026 Jul;21(3):160-166. Epub 2026 Jul 27
Authors: Palakkot S, Banik A
PubMed: 42621238
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Neuroprotection of engineered Clostridium butyricum-pMTL007-GLP-1 in A53T α-synuclein (α-syn) mouse model via PI3K/AKT/GSK-3β.

J Zhejiang Univ Sci B. 2026 Jun 27;27(8):872-887.
Authors: Fang X, Wang Y, Long Z, Liao B, Wang B, Hong D, Luo J, Chen T
PubMed: 42599178
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Tracing neuroinflammation in neurodegeneration: insights from a scoping review on biofluid biomarkers.

Brain Commun. 2026;8(4):fcag289. Epub 2026 Aug 6
Authors: van de Zande NA, Ruiter CC, Polman MA, Brama SC, Roos RA, Kremer PH, de Bot ST
PubMed: 42598675
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Digital clock assessment in South Asian setting: pilot study.

NPJ Dement. 2026;2 Epub 2026 Feb 2
Authors: Jagannathan R, Mohan D, Komal R, Kondal D, Subramani P, Menon P, Pai R, Anjana RM, Ali MK, Mohan S, Alladi S, Tandon N, Prabhakaran D, Mohan V, Levey AI, Narayan KM, Goldstein FC
PubMed: 42598272
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Effects of mindfulness-based exercise on Parkinson's disease and Alzheimer's disease: a systematic review and meta-analysis.

Front Neurol. 2026;17:1860499. Epub 2026 Jul 30
Authors: Zhang M, Zhang Y, Zhang Z, Jia X, Lei S, Bu N, Wang Y, Bai Y, Wang S
PubMed: 42598237
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Clustered pattern projection for EEG dementia classification: evaluating the reliability of disorder patterns.

Front Neurosci. 2026;20:1871265. Epub 2026 Jul 30
Authors: Kang H, Kang J, Zeki M, Seo JH
PubMed: 42597859
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Replicable generation and stable maintenance of rhesus macaque iPSCs for in vitro modeling of genetic frontotemporal dementia.

Front Cell Dev Biol. 2026;14:1833030. Epub 2026 Jul 30
Authors: Colwell JC, Maufort JP, Williams KM, Makulec AT, Fiorentino MV, Metzger JM, Simmons HA, Basu P, Malicki KB, Karch CM, Marsh JA, Emborg ME, Schmidt JK
PubMed: 42597777
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Toward precision neuroscience in Alzheimer's disease: the role of multimodal AI.

Front Aging Neurosci. 2026;18:1903637. Epub 2026 Jul 30
Authors: Martínez-Molina N, Orte S, Migliorelli C, Ribas V
PubMed: 42597745
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Mental health and gut-brain crosstalk: implications for depression and Alzheimer's disease.

Neurosci Appl. 2026;5:107023. Epub 2026 Jul 24
Authors: Skourti K, Katsaitis F, Pavlidi P, Anesti M, Balla J, Emvalomatis A, Kokras N, Dalla C, Sotiropoulos I
PubMed: 42597739
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Differential detectability of pericyte and blood-brain barrier readouts across the Alzheimer's disease clinical continuum: a systematic review and meta-analysis.

Front Aging Neurosci. 2026;18:1870764. Epub 2026 Jul 30
Authors: Wang W, Xu H, Wu T, Zhang Y, Tao M, Zhao X, Lu J, Tang X, Zhang S, Zhang Y, Nan H
PubMed: 42597738
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Metabolic cell death networks in Alzheimer's disease: mechanistic links and therapeutic perspectives of ferroptosis, cuproptosis, and disulfidptosis.

Front Cell Dev Biol. 2026;14:1879368. Epub 2026 Jul 30
Authors: Ding S, Guo Z, Ji H, He J
PubMed: 42597683
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Toward personalized medicine in AD/ADRD through genetic-exposome dementia risk assessments.

NPJ Dement. 2026;2(1):70. Epub 2026 Aug 12
Authors: Tolosa-Tort P, Okorie M, Chatterjee A, Boeriu AI, Sharma RU, Andrews SJ
PubMed: 42597443
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Medical comorbidities of patients receiving amyloid-targeting treatments in a memory clinic.

Alzheimers Dement (Amst). 2026;18(3):e70445. Epub 2026 Aug 12
Authors: Powell WJ, Schindler SE, Jiménez-Mausbach M, Oh IY, Hofmann A, Snider BJ, Paczynski M, Ghoshal N, Payne PR, Lai AM, Hofford MR, Gupta A
PubMed: 42597430
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Inter-software variability of Centiloid quantification in amyloid PET: A head-to-head comparison of five software platforms.

Alzheimers Dement (Amst). 2026;18(3):e70443. Epub 2026 Aug 12
Authors: Zhang J, Burkett BJ, Schwarz CG, Dizdar N, Johnson MP, Bilgin C, Kemp BJ, Durski JM, Lowe V, Johnson DR
PubMed: 42597411
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The changing epidemiology of infection-associated mortality in Alzheimer's disease in the United States, 1999-2024.

Front Aging Neurosci. 2026;18:1885030. Epub 2026 Jul 30
Authors: Miao X, Zhang Y, Gao C, Meng W, Yan J, Zeng T, Tang G
PubMed: 42597288
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White matter abnormalities in amyotrophic lateral sclerosis: a free water imaging study.

Front Neurosci. 2026;20:1899073. Epub 2026 Jul 30
Authors: Liu Z, Yang H, Cui J, Guan Z, Gao D, Feng P, Yang H, Li W, Zhao Y, Yang Q, Zheng X, Liu Q, Geng Z
PubMed: 42597242
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Dual-task, single challenge: functionality as an early marker of cognitive decline.

Dement Neuropsychol. 2026;20:e20250349. Epub 2026 Aug 14
Authors: de Almeida JS, Rosendo IL, Plácido JD, Silva FO, Ferreira JV, Figueiredo LF, Deslandes AC, Gomes DC
PubMed: 42603030
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Change in brain glucose metabolism and cognition in amnestic MCI patients in relation to amyloid accumulation: A 3-year follow-up study.

Aging Brain. 2026;10:100165. Epub 2026 Aug 6
Authors: Rauhala E, Johansson J, Karrasch M, Eskola O, Tolvanen T, Rajander J, Rinne JO
PubMed: 42602999
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GLP-1-based incretin therapy is associated with lower incident Alzheimer's disease and cardiorenal events in adults with documented neuropsychiatric, cognitive, or sensory risk.

Biol Methods Protoc. 2026;11(1):bpag043. Epub 2026 Aug 3
Authors: Murugadoss K, Venkatakrishnan AJ, Soundararajan V
PubMed: 42602880
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Update and recommendations on genetic testing for amyotrophic lateral sclerosis in clinical practice: a Brazilian expert view.

Front Neurol. 2026;17:1928302. Epub 2026 Jul 31
Authors: Sgobbi P, de Rezende Pinto WB, Seneor DD, Orsini M, Chieia MA, Oliveira AS
PubMed: 42602697
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Automated differentiation of non-fluent and logopenic primary progressive aphasia in Italian speakers using acoustic and linguistic speech measures.

Alzheimers Dement (Amst). 2026;18(3):e70450. Epub 2026 Aug 14
Authors: Pierotti F, Morinelli C, Moschini V, Padiglioni S, Giacomucci G, Mazzeo S, Micera S, Bandini A, Bessi V
PubMed: 42602553
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Comparison of double-blind and open-label decline rates in lecanemab and donanemab trials in Alzheimer's disease.

BMJ Neurol Open. 2026;8(2):e001649. Epub 2026 Aug 10
Authors: Dwivedi AK, Imbimbo BP, Abanto J, Espay AJ
PubMed: 42602524
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Microstates and connectivity states reveal task-related network reorganization in Alzheimer's disease patients.

Clin Neurophysiol Pract. 2026;11:664-676. Epub 2026 Jul 28
Authors: Kim JW, Yeldesbay A, Kehm C, Fassbender RV, Onur OA, Rosjat N, Fink GR, Daun S
PubMed: 42602413
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TREM2 as a central immunometabolic hub in Alzheimer's disease: linking microglial states, lipid stress, and disease-stage-specific intervention.

Front Immunol. 2026;17:1893545. Epub 2026 Jul 31
Authors: Yang G, Xu X, Xu Y
PubMed: 42602355
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Dual inhibitory potential of N-methylcytisine against GSK-3β and AChE: implications for Alzheimer's disease treatment.

Open Life Sci. 2026 Jan;21(1):20251363. Epub 2026 Aug 17
Authors: Tarbiat S, Kantarci-Carsibasi N
PubMed: 42602264
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Dynamic structural profiling of PINK1 mutations (T313M and L347P) reveals a vital molecular perturbation namely phospho-Serine 65 ubiquitin recognition point in mitophagy mediated autosomal recessive Parkinson's disease (ARPD).

Front Mol Neurosci. 2026;19:1875988. Epub 2026 Jul 31
Authors: Vincent D, Sudandiradoss C
PubMed: 42602159
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Personalized, home-based transcranial alternating current stimulation for memory improvement in mild cognitive impairment: randomized, sham-controlled clinical trial protocol.

Front Aging Neurosci. 2026;18:1882406. Epub 2026 Jul 31
Authors: Bréchet L, Bouhour C, Rochas V, Mekrom VA, Eshmawey M, Unschuld PG
PubMed: 42602062
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Long non-coding RNAs in glial cells: key drivers of neuroinflammation in cognitive disorders.

Front Aging Neurosci. 2026;18:1849634. Epub 2026 Jul 31
Authors: Malatino C, Raffaele I, Quartarone A, Raciti G, Anchesi I, Iraci N, De Cola MC
PubMed: 42601953
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Neurogenesis defects in iPSC-derived midbrain organoids of early-onset Parkinson's disease with 22q11.2 deletion syndrome.

Front Cell Neurosci. 2026;20:1906023. Epub 2026 Jul 31
Authors: Ueki S, Kimura T, Tohge R, Tamada A, Oki M, Yakushiji Y, Inoue H, Kaneko S, Muguruma K
PubMed: 42601939
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Microstructural white matter alterations in dementia with lewy bodies and Alzheimer's disease: a diffusion tensor imaging and neurite orientation dispersion and density imaging study.

Front Aging Neurosci. 2026;18:1830477. Epub 2026 Jul 31
Authors: Guo Y, Niu X, Xia Y, Yang Y, Fu X, Li T, Zhang Y, Ji Y, Ni H
PubMed: 42601937
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Amyloid-β modulates APOE ε4 effects on cognition but not on targeted structural or functional connectivity measures over 2 years in pre-dementia adults.

Front Aging Neurosci. 2026;18:1889743. Epub 2026 Jul 31
Authors: Wei H, Zhang T, Liang Z, Li M, Kong M, Ba M
PubMed: 42601919
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Evaluating inclusion of continuous multivariable cognitive scores for operational enrichment of preclinical Alzheimer's disease trials: a retrospective emulation study.

JAR Life. 2026;15:100081. Epub 2026 Aug 8
Authors: Bayly H, Salvati L, Lenio S, Mez J, Alosco ML, Tripodis Y
PubMed: 42604096
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Psychometric properties of the Rowland Universal Dementia Assessment Scale - Peruvian Version among Indigenous Amazonian communities.

NPJ Dement. 2026;2(1):72. Epub 2026 Aug 14
Authors: Boluarte Carbajal A, Sanchez Boluarte AN, Nolasco M, Diaz MM
PubMed: 42603873
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Exploring the effect of red and near-infrared light on neurodegenerative disease: A focus on amyotrophic lateral sclerosis, Charcot's devastating disease of the motor system.

Int Rev Neurobiol. 2026;189:205-236. Epub 2026 Feb 9
Authors: Valverde A, Blasco H, Corcia P, Herault O, Magistretti P, Herault L, Cali C, Bartesaghi L, Stone J, Mitrofanis J
PubMed: 42613144
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Spatiotemporal Dynamics and Cellular States of Neuroinflammation in Amyotrophic Lateral Sclerosis: Implications for Stage‑Specific Therapeutics.

ASN Neuro. 2026;18(1):2715625. Epub 2026 Aug 18
Authors: Lv C, Zhu W, Wen X, Da Y
PubMed: 42610209
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Role of microRNAs in major brain diseases, focusing on neuroinflammation and neuronal apoptosis.

Iran J Basic Med Sci. 2026;29(6):844-869.
Authors: Aziz N, Hussain G, Abbas QA
PubMed: 42610130
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A regional registry ensures clinical guideline adherence and economic sustainability of Alzheimer's disease treatment: a 12-year population-based study in Catalonia.

Front Pharmacol. 2026;17:1848809. Epub 2026 Jul 22
Authors: Umbria M, Exposito J, Gasol M, Vallano A
PubMed: 42610018
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Huanglian Jiedu decoction ameliorates Alzheimer's disease by regulating calcium homeostasis via mitochondria-associated endoplasmic reticulum membranes.

Iran J Basic Med Sci. 2026;29(6):927-934.
Authors: Yuan Y, Li Z, Wang R, Zhao H, Song J
PubMed: 42609945
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Interpretable Alzheimer's Diagnosis via Multimodal Fusion of Regional Brain Experts.

Proc (IEEE Int Conf Healthc Inform). 2026;2026:311-320. Epub 2026 Aug 12
Authors: Zhuang F, Yang S, Aliyeva D, Wen Z, Duong-Tran D, Davatzikos C, Chen T, Wang S, Shen L
PubMed: 42609893
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Staging and Pseudotime Inference of Alzheimer's Disease Progression using Multimodal Imaging Data.

Proc (IEEE Int Conf Healthc Inform). 2026;2026:331-340. Epub 2026 Aug 12
Authors: Nair AA, Wen Z, Wang Z, Yan J, Saykin AJ, Huang H, Thompson PM, Davatzikos C, Shen L
PubMed: 42609863
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Targeting cellular senescence through nutritional senotherapeutics in brain aging and neurodegenerative diseases.

Front Nutr. 2026;13:1824908. Epub 2026 Aug 3
Authors: Salas-Venegas V, López-Diazguerrero NE, Ramírez-Carreto RJ, Konigsberg M, Chavarría A
PubMed: 42609608
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High-frequency taVNS modulates olfaction-related brain activity in patients with subjective cognitive decline.

Front Hum Neurosci. 2026;20:1888005. Epub 2026 Aug 3
Authors: Huang J, Li X, Zhou K, Liu B, Wei Y, Guo H, Wei S, Xu S, Liu Y, Huang J, Deng D, Liang L
PubMed: 42609487
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A locus coeruleus-centric framework for novelty, salience, and gamma oscillations: implications for neurostimulation, aging, and disease.

Front Aging Neurosci. 2026;18:1895931. Epub 2026 Aug 3
Authors: Jackson BL
PubMed: 42609354
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A multilevel conceptual framework for dementia: from life-course mechanisms to public health strategies.

Braz J Med Biol Res. 2026;59:e15447. Epub 2026 Aug 17
Authors: Aliberti MJ, Paiva JE
PubMed: 42615668
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Regional amyloid accumulation, post-traumatic distress, and intrusive symptoms in cognitively unimpaired older adults at risk for Alzheimer's.

Alzheimers Dement (Amst). 2026;18(3):e70410. Epub 2026 Aug 18
Authors: Palpatzis E, Colceriu CM, Shekari M, Akinci M, Suárez-Calvet M, Grau-Rivera O, Sánchez-Benavides G, Gispert JD, Arenaza-Urquijo EM, ALFA study
PubMed: 42614877
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Experience with donanemab over a 1-year period: observations of side effects and compliance from a regional specialty medical center.

Alzheimers Dement (Amst). 2026;18(3):e70438. Epub 2026 Aug 18
Authors: Shields LB, Hust HS, Cooper GE, Kluthe T, Hart RN, Thaliath AP, Dennis BC, Freeman SW, Cain JF, Shang WY, Wasz KM, Orr AT, Shields CB, Barve SS, Pugh KG
PubMed: 42614867
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Harmonizing biofluid specimen collection and biomarker quantification in Diverse Vascular Contributions to Cognitive Impairment and Dementia (DVCID) study.

Alzheimers Dement (Amst). 2026;18(3):e70435. Epub 2026 Aug 17
Authors: Zhou S, Conston J, Suthprasertporn N, Denis-Romero R, Lucente JD, White JL, Mielke MM, Harvey D, Rajan KB, Johnson DK, Fornage M, DeCarli C, Hinman JD, Jin LW, DVCID Study Investigators
PubMed: 42614671
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Microglia-astrocyte crosstalk as a key organizing principle of Alzheimer's disease: from homeostatic cooperation to maladaptive signaling loops.

Front Aging Neurosci. 2026;18:1908574. Epub 2026 Aug 4
Authors: Gong M, Lan J, Miao J
PubMed: 42614559
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Clinical tools to differentiate behavioral variant frontotemporal dementia from phenocopies.

Alzheimers Dement (Amst). 2026;18(3):e70452. Epub 2026 Aug 17
Authors: Flavell J, Lee S, McElligott CA, Coleman FM, Fazlollahi A, McCann EG, Nguyen DD, Nestor PJ
PubMed: 42614532
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Associations of proteomic and epigenetic aging clocks with Alzheimer's disease phenotypes: An exploratory analysis.

Alzheimers Dement (Amst). 2026;18(3):e70456. Epub 2026 Aug 17
Authors: David Sarmento C, Drouard G, Saari TT, Aaltonen A, Heikkinen A, Hukkanen M, Palviainen T, Herukka SK, Kokkola T, Kärkkäinen S, FinnGen, Palotie A, Julkunen V, Runz H, Kaprio J, Ollikainen M, Vuoksimaa E
PubMed: 42614490
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Parkinson's Disease: Immunometabolic Control Points Across Neural, Vascular, and Peripheral Systems.

Parkinsons Dis. 2026;2026:5349481. Epub 2026 Aug 17
Authors: Narvaez Irizarry Felix Y, Bermudez Adorno Alondra M, Boris E, Lilia K, Mikhail I
PubMed: 42614481
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Graphomotor performance as a quantitative marker of Alzheimer's disease: a tablet-based case-control ROC study.

Front Neurosci. 2026;20:1900444. Epub 2026 Aug 4
Authors: Gorzelańczyk EJ, Laskowska E, Pasgreta K, Kamiński P, Kawala-Sterniuk A, Walecki P
PubMed: 42614446
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Emerging neuroprotective mechanisms and therapeutic potential of natural polysaccharides in Alzheimer's disease.

Front Aging Neurosci. 2026;18:1877358. Epub 2026 Aug 4
Authors: Muhammad N, Ai R, Yang L, Cui Y, Wang L, Weng S, Wang Y, Kakar MU, Khan S, Ahmad S, Iqbal I
PubMed: 42614314
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Association between different sodium-glucose co-transporter 2 inhibitors and the risk of dementia: a network meta-analysis.

Front Endocrinol (Lausanne). 2026;17:1777151. Epub 2026 Aug 4
Authors: Meng Z, Wu H, Miao Y, Qi W, Sha M
PubMed: 42614235
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Cerebellar ataxia-onset ALS with SOD1 D91A mutation: a rare phenotype.

Front Neurol. 2026;17:1889931. Epub 2026 Aug 4
Authors: Shevchuk DV, Nuzhnyi EP, Fedotova EY, Ershova MV, Minaev IV, Anikin GA, Protsenko AR, Abramycheva NY, Zakharova MN, Illarioshkin SN
PubMed: 42614182
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Imaging and Characterization of Ganglioside-Induced Amyloid Fibril Formation.

Methods Mol Biol. 2026;3035:437-446.
Authors: Matsubara T
PubMed: 42613541
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Zinc-finger ubiquitin-binding domain of histone deacetylase 6 modulates Tau structure and function.

Methods Enzymol. 2026;733:81-110. Epub 2026 Jun 8
Authors: Balmik AA, Chinnathambi S
PubMed: 42624569
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Histone Decatylase 6 and Tau-induced microglial chemotaxis by trans-well migration and wound-scratch assay.

Methods Enzymol. 2026;733:385-406. Epub 2026 Jul 2
Authors: Chinnathambi S, Desale SE
PubMed: 42624566
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Histone deacetylases in neurodegeneration and neuronal plasticity.

Methods Enzymol. 2026;733:321-366. Epub 2026 Jul 15
Authors: Mehta B, Nambiar S, Shirke O, Pandita S, Markandeya YS
PubMed: 42624563
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Synergetic inhibition of deubiquitinases and acetyltransferases to regulate tau acetylation and aggregation in SH-SY5Y cell line model of Alzheimer's disease.

Methods Enzymol. 2026;733:297-319. Epub 2026 Jun 6
Authors: K C B, D K H, Priyadarshini P
PubMed: 42624562
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Histone deacetylase as a potential therapeutic target for memory dysfunction during aging and neurodegenerative disorders.

Methods Enzymol. 2026;733:279-295. Epub 2026 Jun 8
Authors: Singh P, Thakur MK
PubMed: 42624561
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Epigenetic modulators as therapeutics for neurodegenerative disorders/Alzheimer's disease.

Methods Enzymol. 2026;733:163-222. Epub 2026 Jul 15
Authors: Halder D, Prajapati D, Banerjee T, Biswas S, Ghosh B
PubMed: 42624557
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Thinking Beyond Common Diagnoses: A Case Report of Creutzfeldt-Jakob Disease.

WMJ. 2026;125(3):402-406.
Authors: Licata T, Huh W, Bolan M
PubMed: 42623627
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IMAGING OF THE BONE ARCHITECTURE IN THE CONTEXT OF ALZHEIMER DISEASE.

Osteoarthr Imaging. 2026;6 Suppl 1:100445.
Authors: Suryadevara V, Valiya AK, Krehbial CJ, Karra S, Kluppel M, Willis MS
PubMed: 42622180
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Editorial: Molecular and cellular pathways underlying neurodegenerative disorders.

Front Cell Dev Biol. 2026;14:1943531. Epub 2026 Jul 31
Authors: Bougea A, Ouro A, Reiss AB
PubMed: 42621955
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Cerebrospinal fluid biomarkers in E200K genetic Creutzfeldt-Jakob disease: a national study from an endemic Slovak cohort.

Front Neurosci. 2026;20:1906444. Epub 2026 Aug 5
Authors: Zakova D, Koscova S, Melicherova K, Janakova A, Szarvasova Z, Kosorinova D, Stelzer M
PubMed: 42621919
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Structural changes in gray matter and white matter across the Alzheimer's disease continuum.

Front Neurosci. 2026;20:1853132. Epub 2026 Aug 5
Authors: Lin S, Xue M, Wang T, Chen Y, Sheng C, Sun J, Sui Y, Zou W, Lian J, Peng J, Zhang T, Wang W
PubMed: 42621887
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Correction: Comorbidity sequence, sex, and APOE-genotype forecast Alzheimer's disease diagnosis.

Front Med (Lausanne). 2026;13:1947497. Epub 2026 Aug 5
Authors: Merlini S, Gatta R, Orini S, Basharat A, Farooq M, Brinton RD, Vitali F
PubMed: 42621871
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An interpretable multimodal ensemble assessment framework for Alzheimer's disease cognitive staging.

Front Neurol. 2026;17:1911900. Epub 2026 Aug 5
Authors: Zhang J, Yuan B, Liu Y, Xue Z
PubMed: 42621498
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Engaging Hispanic/Latino young adults in Alzheimer's disease research through boot camp translation.

Alzheimers Dement (N Y). 2026;12(3):e70309. Epub 2026 Aug 19
Authors: Martinez MN, Moeller S, Arroyo-Miranda M, Lafont-Tanner D, John SE, Kunik M, Vardeman J, Mullen R, Pressman P, Stocker M, Lopez-Esquibel N, Woods SP, Medina LD
PubMed: 42621272
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Post-marketing safety signals and report-level ARIA-E stratification for lecanemab and donanemab: an integrated FAERS and WHO-VigiAccess pharmacovigilance study.

Ther Adv Drug Saf. 2026;17:20420986261473013. Epub 2026 Aug 18
Authors: Xue WY, Li X, Li WT, Qin BZ, Wang CZ, Liu T, Wang M
PubMed: 42621237
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FIS1 dependent peripheral fission exacerbates mitochondrial fragmentation and dysfunction in prion diseases.

Front Neurosci. 2026;20:1893232. Epub 2026 Aug 5
Authors: Gou F, Li Z, Li J, Yang D, Zhao M, Wang D, Wen P, Sun Z, Wang J, Fan Q, Dai Y, Zhao D, Yang L
PubMed: 42621101
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Neurogenesis and neuroplasticity activities of natural products: therapeutic potential in Alzheimer's disease.

Front Pharmacol. 2026;17:1863841. Epub 2026 Aug 5
Authors: Shaheen AM, Mousa MH, Hindam MO, El-Dessouki AM, Fahim SA, Hal DM, Ahmed S, El-Shiekh RA, Khalifa HO
PubMed: 42621019
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Translating peripheral blood biomarkers into Alzheimer's disease care: an exploratory dual-pathway model of immune and viral dynamics in behavioral and psychological symptoms of dementia.

Front Aging Neurosci. 2026;18:1867226. Epub 2026 Aug 5
Authors: Wu CT, Chou SP, Chang CR, Chang CC, Chu CI
PubMed: 42621008
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Alzheimer's disease polygenic risk score associates with hippocampal subfield atrophy and immune-related genetic mechanism.

Front Aging Neurosci. 2026;18:1875172. Epub 2026 Aug 5
Authors: Olivé C, de Rojas I, Zhang L, Sotolongo-Grau O, Quintela I, García-González P, Puerta R, Montrreal L, Bayón P, Rovira M, Valenzuela A, Capdevila-Bayo M, Muñoz Á, Miguel A, Calm B, Calero M, Rábano A, Belén Pastor A, Del Ser T, Medina M, Carracedo Á, Ramírez A, Molina-Porcel L, Montalbán X, Cano A, Valero S, Marquié M, Sanz P, Sánchez-Juan P, Boada M, Strange B, Fernández MV, Ruiz A
PubMed: 42620948
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Impact of exercise on cognitive efficiency in older adults with subjective memory complaints: a randomized clinical trial.

Front Aging Neurosci. 2026;18:1875431. Epub 2026 Aug 5
Authors: Silva GO, Clark M, Lautenschlager NT, Thomas HJ, Smith KJ, Maslen BA, Cox KL, Pestell CF, Ainslie PN, Carter HH, Naylor LH, Green DJ
PubMed: 42620947
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Research progress on the role of the locus coeruleus in cognitive function.

Front Hum Neurosci. 2026;20:1830622. Epub 2026 Aug 5
Authors: Li X, Liang X, Yuan X, Dai N, Qian K, Li K, Zhang Y, Wang H
PubMed: 42620451
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Why dementia is often not diagnosed by subtype: care pathways and imaging access in the United Arab Emirates.

Front Psychiatry. 2026;17:1910567. Epub 2026 Aug 5
Authors: Javaid SF, Al Mugaddam F, Shebani Z, Bokhari SA
PubMed: 42620425
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Divergent trends in Alzheimer's disease burden: a comparative analysis of the US and G20 nations.

Int J Public Health. 2026;71:1609525. Epub 2026 Aug 5
Authors: Zou Y, Wang Q, Zhang Q, Cheng X
PubMed: 42620417
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Loss of epigenetic adaptation to a high-fat diet in alpha-synuclein transgenic mice.

Front Cell Neurosci. 2026;20:1901103. Epub 2026 Aug 5
Authors: Hoof V, Schaffner SL, Dever K, MacIsaac J, Rotermund C, Kobor MS, Kahle PJ, Hentrich T, Schulze-Hentrich JM
PubMed: 42620320
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