Alzforum - Papers of the Week: 30 Oct - 5 Nov 2026

Construction of a robust fluorescent probe for the rapid evaluation of natural products' inhibition of Alzheimer's disease.

Anal Chim Acta. 2026 Dec 8;1426:346374. Epub 2026 Oct 12
Authors: Xu X, Xu X, Zhou L, Wang W, Ouyang M, Zheng J, Zhang L
PubMed: 42967802
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Association of LATE-NC With Neuropathologic Lesions and Cognitive Abilities: A Population-Based Autopsy Study.

Neurology. 2026 Dec 8;107(11):e218694. Epub 2026 Nov 5
Authors: Matos Silva C, Justo AF, Ribeiro Paes V, Grinberg LT, Pasqualucci CA, Ferriolli E, Nitrini R, Nelson PT, Paraizo Leite RE, Suemoto CK
PubMed: 42987245
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The microglial lineage: from molecular states to context-dependent functions.

Cell Insight. 2026 Dec;5(6):100378. Epub 2026 Oct 10
Authors: Li C, Wu Z, Xiang X, Li H
PubMed: 42959446
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Black Myrobalan (Terminalia chebula) as a potential multitarget neuroprotective agent: Translational insights and future directions in neurodegenerative diseases.

Biochem Biophys Rep. 2026 Dec;48:102850. Epub 2026 Oct 24
Authors: Ghiasvand K, Meftahi GH
PubMed: 42964735
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Early HbA1c in new metformin users: A dementia risk reassessment trigger, not a cognitive target.

Am J Med. 2026 Dec;139(12):e378.
Authors: Wang M, Chu X
PubMed: 42971697
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Sleep and Neurodegeneration: Artificial Intelligence Applications in Early Detection and Personalized Care.

Sleep Med Clin. 2026 Dec;21(4):547-560. Epub 2026 Oct 1
Authors: Ibrahim A, Ganglberger W, Cesari M, Stefani A
PubMed: 42977363
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Statement of Retraction: Safinamide protects against amyloid β (Aβ)-induced oxidative stress and cellular senescence in M17 neuronal cells.

Bioengineered. 2026 Dec;17(1):2745625. Epub 2026 Nov 5
Authors:
PubMed: 42987352
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Statement of Retraction: Magnolol attenuates the locomotor impairment, cognitive deficit, and neuroinflammation in Alzheimer's disease mice with brain insulin resistance via up-regulating miR-200c.

Bioengineered. 2026 Dec;17(1):2745454. Epub 2026 Nov 5
Authors:
PubMed: 42987276
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Systems Pharmacology and Molecular Docking-Based Investigation of the Molecular Mechanism of Astilbin in the Treatment of Alzheimer's Disease.

Biomed Chromatogr. 2026 Dec;40(12)
Authors: Huang S, Lv Q, Chen L, Zhou C, Liao Y, Pan R
PubMed: 42984463
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Molecular determinants of α-synuclein toxicity and aggregation revealed by deep mutagenesis.

Biochem Soc Trans. 2026 Nov 25;54(11):1581-1594.
Authors: Noh D, Newberry RW
PubMed: 42973104
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Phytomicronutrients in neurodegeneration: modulating microglial dynamics for neuroprotection.

Z Naturforsch C J Biosci. 2026 Nov 25;81(11-12):703-737. Print 2026 Nov 25
Authors: Adhikary K, Prameela G, Das J, Ramzan M, Ganguly K, Datta N, Banerjee P, Barman S, Sridhar SB, Taj T, Mondal M, Ashique S, Chopra S, Chopra H
PubMed: 42980191
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The Importance of Biologic Characterization of Neurodegenerative Dementias.

Neurology. 2026 Nov 24;107(10):e218775. Epub 2026 Nov 2
Authors: Irwin DJ
PubMed: 42970750
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Plasma P-Tau217 and NfL Longitudinal Changes Across Neurodegenerative Diseases: Impact of α-Synuclein in Alzheimer Disease.

Neurology. 2026 Nov 24;107(10):e218685. Epub 2026 Nov 2
Authors: Esteller-Gauxax D, Pérez-Millan A, Sarto J, Guillén N, Puey R, Collet-Romà T, Comas-Albertí A, Borrego-Écija S, Canasto P, Martín-Sobrino I, Massons M, Bosch B, Rigol A, Patricio V, Juncà-Parella J, Fernández-Villullas G, Alcón D, García RR, Rondán LN, Augé Fradera JM, Antonell A, Falgàs N, Tort-Merino A, Lladó A, Sánchez-Valle R, Balasa M
PubMed: 42970748
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A fibril-selective single-domain antibody targets pathogenic amyloid-β assemblies and protects human neurons.

iScience. 2026 Nov 20;29(11):117946. Epub 2026 Oct 21
Authors: Greenlee MA, Amniouel S, Rivera I, Suh J, Martinez NJ, Simeonov A, Head E, Tycko R, Zheng W, Fleming BD, Zhang Q
PubMed: 42960253
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On the Need to Revise the Amyloid Cascade Hypothesis.

Chembiochem. 2026 Nov 12;27(21)
Authors: Teplow DB, Raskatov JA
PubMed: 42985938
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Molecular Insights on the Reduction-Dependent Electronic Modulation of Graphene Oxide Surface Toward Reactivity and Acetylcholinesterase Inhibition of Alzheimer's Drugs.

Chemphyschem. 2026 Nov 12;27(21)
Authors: Phanrang PT, Upadhyaya J, Chandra AK, Mitra S
PubMed: 42984381
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Amino Acid Functionalization Influences the Binding of Thiophene-Vinylene-Benzothiazolium-Based Fluorescent Ligands to Protein Deposits in Tissue Sections With Alzheimer's Disease Pathology.

ChemMedChem. 2026 Nov 12;21(21)
Authors: Björk L, Vidal R, Ghetti B, Lindgren M, Klingstedt T, Nilsson KP
PubMed: 42978234
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Mechanistic understanding of the role of the lung-brain axis in the pathogenesis of PM2.5-induced Alzheimer's disease.

Clin Sci (Lond). 2026 Nov 11;140(11):2611-2635.
Authors: Defrancesco AD, Wang B, Yi C, Oliver BG, Chen H
PubMed: 42984379
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Hepatocyte-derived exosomal miR-122 mediates liver-to-brain crosstalk and neuroinflammation in alcohol-exposed Alzheimer's disease mice.

Proc Natl Acad Sci U S A. 2026 Nov 10;123(45):e2535191123. Epub 2026 Nov 3
Authors: Brezani V, Ortega-Ribera M, Rezagholizadeh N, Joshi R, Brezani V, Babuta M, Santos BA, Zivny A, Thevkar Nagesh P, Ghiran I, Michelle Shreyer E, Minchenberg SB, Flavin A, Szabo G
PubMed: 42975926
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A functional connectome identifies vulnerability to cognitive decline and Alzheimer's disease progression.

Sci Adv. 2026 Nov 6;12(45):eaed9351. Epub 2026 Nov 4
Authors: Zhao K, Xie H, Fonzo GA, Carlisle NB, Jacobs T, Osorio RS, Church A, Lin FV, Zhang Y, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42981415
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Common transcriptional changes in the brain during hibernation and Alzheimer's disease.

Sci Adv. 2026 Nov 6;12(45):eaeg3486. Epub 2026 Nov 4
Authors: Largo-Barrientos P, Praschberger R, León-Espinosa G, Bultynck PJ, Mallopoulou A, Machado JF, Poovathingal S, Davie K, Verstreken P
PubMed: 42981396
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Ethnoracial and Linguistic Diversity in Treatment Research for Primary Progressive Aphasia: A Systematic Review.

Am J Speech Lang Pathol. 2026 Nov 5;35(6):3597-3617. Epub 2026 Nov 2
Authors: Manning R, Bao W, Quiñones Vieta MF, Ansín Gómez L, Acosta JA, de Leon J, Filella Mercè J, García Hernandez E, Gutiérrez Sánchez KP, Holst Chaires JC, Marqués Kiderle S, Cruz DF, Yoshimoto G, Matías-Guiu JA, Montagut Colomer N, Wagner Rodríguez CA, Santos Santos MÁ, Henry ML, Grasso SM
PubMed: 42970452
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Continuous-Speech Parkinson's Disease Detection Using Acoustic and Inharmonicity Features.

J Voice. 2026 Nov 5; Epub 2026 Nov 5
Authors: Li R, Momeni N, Whitling S, Jakobsson A
PubMed: 42988717
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Quantifying "Normal Pressure Hydrocephalus"-like Brain Morphometry patterns in an Alzheimer's Disease Cohort.

AJNR Am J Neuroradiol. 2026 Nov 5; Epub 2026 Nov 5
Authors: Bacha L, Griffa A, Kurz FT, Hutuca I, Battistini K, Venkategowda PB, Prabhu KM, Thiran JP, Maréchal B, Disselhorst J, Di Noto T, Allali G, Lovblad KO, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42988576
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Astragalin ameliorates cognitive dysfunction in Alzheimer's disease model mice: Role of the iron metabolism-autophagy axis.

Brain Res. 2026 Nov 5;:150626. Epub 2026 Nov 5
Authors: Wang C, Huang W, Zhang W, Zhang L, Zhou C, Yang Y, Wang S, Lin J, Liu J, Li G, Yang Y, Ma Y
PubMed: 42988349
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The dual role of microglia in cognitive dysfunction: from neuroinflammation to therapeutic opportunities.

Neurobiol Dis. 2026 Nov 5;:107678. Epub 2026 Nov 5
Authors: Wang Y, Qiang C, Xu X, Zhou S, Liu C, Wang J
PubMed: 42988339
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Poly(lactic-co-glycolic acid) immunomodulatory nanoparticles attenuate neuroinflammation and Alzheimer's disease-related pathology in 5xFAD mice.

Exp Neurol. 2026 Nov 5;409:116116. Epub 2026 Nov 5
Authors: Sanders B, Korthauer M, Parihar KS, Ifergan I
PubMed: 42988308
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RDP-modified extracellular vesicles from brain organoid-derived mesenchymal stem cells improve the behavior and pathology of 5×FAD mice.

Pharmacol Res. 2026 Nov 5;:109739. Epub 2026 Nov 5
Authors: Huang E, He Y, Ran X, Lin B, Zhang Y, Liao H
PubMed: 42988190
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Masitinib-loaded poly(lactic-co-glycolic acid) nanoparticles reinstate lysosomal acidification and drive immunomodulation in Alzheimer's disease.

J Control Release. 2026 Nov 5;:115518. Epub 2026 Nov 5
Authors: Huang Q, Chen Y, Liu Y, Lv Y, Xie X, Liyang C, Tong F, Gao H, Sun J
PubMed: 42988058
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PRKN-independent mitophagy regulators in dopaminergic neurons identified by genome-wide CRISPR screening.

Neurosci Res. 2026 Nov 5;:105154. Epub 2026 Nov 5
Authors: Nishimura T, Kunisada Y, Li HL, Highfill CA, Nagasawa K, Tsujihata Y
PubMed: 42988051
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Sirt1 modulates p53‑acetylation‑dependent Yy2‑Elf‑1‑associated NLRP3‑relevant signaling in CUMS‑evoked aggravated Alzheimer's disease‑related phenotypes.

Brain Res Bull. 2026 Nov 5;246:112202. Epub 2026 Nov 5
Authors: Chai F, Shan Q, Hu Y, Liu L, Zou J, Xia G, Wang Y
PubMed: 42988015
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Lipid homeostasis and cellular metabolism in neurodegenerative diseases: A maturing framework to guide therapeutic development.

Cell Rep Med. 2026 Nov 5;:103130. Epub 2026 Nov 5
Authors: Isacson O, Tsai LH, Akay L, Platt F, Hallett P
PubMed: 42987827
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Not born in the brain: Bone marrow-derived microglia in human aging.

Cell Stem Cell. 2026 Nov 5;33(11):1745-1747.
Authors: Seo J, Kim S, Lee J, Yoo Y
PubMed: 42987795
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Linguistic features from constrained spontaneous speech as potential markers of preclinical Alzheimer's disease.

J Prev Alzheimers Dis. 2026 Nov 5;13(10):100689. Epub 2026 Nov 5
Authors: Huang H, Li Z, Young CB, Smith V, Ang TF, Kolachalama VB, Au R, Chen J
PubMed: 42987558
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An Electrochemiluminescence Biosensing Platform Based on a Hydrogel-AAO Nanochannel Membrane for GFAP Detection.

ACS Sens. 2026 Nov 5; Epub 2026 Nov 5
Authors: Lai J, Chen J, Huang H, Liu J, Zou Z, Liu J, Lin Z, Hong G
PubMed: 42986928
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ApoE-dependent lipid handling by median eminence microglia supports myelin remodeling and metabolic function.

Cell Rep. 2026 Nov 5;45(11):118255. Epub 2026 Nov 5
Authors: McGrath ER, Folick A, Morrissette LJ, Brown Mayfield SM, Kim H, Weng LF, Pham V, Pillutla SN, Choi MK, Tomaka C, Mechelke AN, Cheang RT, Bolus WR, Schwendeman A, Ntranos V, Koliwad SK, Valdearcos M
PubMed: 42986751
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A human gut-BBB-brain microphysiological model for studying Alzheimer's disease.

Lab Chip. 2026 Nov 5; Epub 2026 Nov 5
Authors: Deng YS, Wang WP, Wang F, Ma GM, Lin JF, Yan CX, Zhou YL, Wang LY, Gong XQ, Sun L, Zhao J, Pei G, Zhang L, Wang WY
PubMed: 42986694
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No association between five-factor personality model and 5-year all-cause mortality in patients with subjective cognitive decline and mild cognitive impairment.

Neuropsychiatr. 2026 Nov 5; Epub 2026 Nov 5
Authors: Harather S, Lehrner J
PubMed: 42986604
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7-Hydroxyflavone Attenuates Amyloid-β-Induced Alzheimer's Disease-Like Pathology Through Modulation of ROS/NLRP3 Inflammasome Signaling.

Neurochem Res. 2026 Nov 5;51(6)
Authors: Rakshit D, Mishra A
PubMed: 42986540
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Astrocytic endoplasmic reticulum stress as an amplifier of neuroinflammation and neurodegeneration in Alzheimer's disease: a narrative review.

Immunol Res. 2026 Nov 5;74(1)
Authors: da Silva Lima B Jr, Dos Santos YT, Farias GC, de Lima Souza EF, de Lima PD, Quaresma JA, da Costa Vasconcelos PF, de Sousa JR
PubMed: 42986483
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Behavioral, biochemical, histological, and electrophysiological changes following intracerebral injection of bone marrow stem cell-derived exosomes in male rat models of Alzheimer's disease.

Exp Brain Res. 2026 Nov 5;245(1)
Authors: Karimi A, Hoveizi E, Khajehpour L, Ghotbeddin Z
PubMed: 42986457
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Effects of high-intensity interval and moderate-intensity continuous training on neuroinflammatory and amyloidogenic pathways in an STZ-induced AD-like model.

Arch Physiol Biochem. 2026 Nov 5;:1-11. Epub 2026 Nov 5
Authors: Safari Moughadam M, Yaghoubi A, Cheragh Birjandi S, Tavakoli M
PubMed: 42986125
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Hesperetin Inhibits Aβ Early Aggregation by Disrupting the Continuity of the β-Sheet Structure.

J Phys Chem B. 2026 Nov 5;130(44):11788-11798.
Authors: Zhang Y, Wu Y, Zhang S, Zhang L, Li X
PubMed: 42986084
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Histidine Tautomerism-Mediated Regulation of β-Hairpin Formation and Primary Nucleation in Amyloidogenic PrP(106-126) A117 V Peptides.

J Phys Chem B. 2026 Nov 5;130(44):11672-11680.
Authors: Wang L, Li J, Altayib A, Zhu R, Sun Y, Shi H, Gao L
PubMed: 42986076
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FE65 Recognition Rewires the Dynamic Contact Network of the Amyloid Precursor Protein Intracellular Domain.

J Phys Chem B. 2026 Nov 5;130(44):11718-11731.
Authors: Mandal N, Skepö M
PubMed: 42986073
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Deep Learning for AD Risk Screening and Progression Prediction.

Adv Sci (Weinh). 2026 Nov 5; Epub 2026 Nov 5
Authors: Lu B, Chen YR, Li RX, Zhang MK, Yan SZ, Chen GQ, Wang JH, Chai WH, Castellanos FX, Thompson PM, Lu J, Han Y, Yan CG
PubMed: 42985795
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Skin Seed Amplification Assay Differentiates Multiple System Atrophy from Parkinson's Disease.

Mov Disord. 2026 Nov 5; Epub 2026 Nov 5
Authors: Kuzkina A, Rodriguez D, Panzer C, Ndayisaba A, Kohl A, Rai S, Gilbert B, Hammerschlag B, Shen K, Harder-Rauschenberger L, Laun O, Meehan J, Perumalla S, Salabasidou E, Jones K, Ceku D, Blum R, Knorr S, Monoranu CM, Sommer C, Volkmann J, Changizi BK, Doppler K, Khurana V
PubMed: 42984461
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Regional Mitochondrial Density Maps Selective Posterior Atrophy in Parkinson's Disease.

Mov Disord. 2026 Nov 5; Epub 2026 Nov 5
Authors: Konuri A, Churchill L, Anderson J, Ignatavicius A, Halliday G, Landin-Romero R, Lewis SJ, Matar E
PubMed: 42984454
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Brain Mechanisms Linking Type 2 Diabetes to Alzheimer Disease: A Multimodal Imaging Framework.

Alzheimer Dis Assoc Disord. 2026 Nov 5; Epub 2026 Nov 5
Authors: Sy J, Tsiknia A, Sussman BL, Ali N, Villarreal I, Juarez M, Estrada JG, Nikkhah Bahrami S, Ganesan S, Nimmo S, Jann K, Wang DJ, Borzage MT, Braskie MN, Yassine HN
PubMed: 42978515
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Evaluating the Interaction of Alzheimer Biomarker Burden and α-Synuclein Status on Cognitive Trajectories in Parkinson Disease: Methodological Challenges and Power Estimates.

Alzheimer Dis Assoc Disord. 2026 Nov 4; Epub 2026 Nov 4
Authors: Ledingham D, Sathyanarayana S, Iredale R, Foster V, Galley D, Lafontant DE, Lad M, Baker MR, Pavese N
PubMed: 42975960
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Current findings, application, and diagnosis of magnetic resonance imaging in amyotrophic lateral sclerosis.

Rev Neurosci. 2026 Nov 4; Epub 2026 Nov 4
Authors: Xu Z, Fan T, Xu R
PubMed: 42975618
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Cytoplasmic TDP-43 aggregation promotes oxidative stress and neurotoxicity through Trx1 mRNA sequestration and translational suppression.

Redox Biol. 2026 Nov 4;98:104469. Epub 2026 Nov 4
Authors: Lee JM, Bok E, Jeon H, Hwang S, Hong J, Lee SB, Cha SJ, Kang SH, Kim HJ, Cheon M, Lee BH, Kim C, Lee SW, Kim SR, Nahm M, Kim J
PubMed: 42987774
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Virtual screening and molecular docking of flavonoid compounds as BACE-1 inhibitors for Alzheimer's Disease: identification of Betagarin as a promising nutraceutical lead candidate.

Nat Prod Res. 2026 Nov 4;:1-11. Epub 2026 Nov 4
Authors: Jha P, Saxena S
PubMed: 42984186
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Brain clearance of protein aggregates in degenerative diseases: the role of microglia and astrocytes.

Transl Neurodegener. 2026 Nov 4;15(1)
Authors: Xiong M, Huang Y, Jiang H, Zhang Z
PubMed: 42983584
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The TNKS/PI31-proteasome axis as a central node in TDP-43 neuropathies.

J Biomed Sci. 2026 Nov 4;33(1)
Authors: Bubphachat P, Majumder P, Wang IF, Huang JK, Kao TJ, Lee YC, Shen CJ, Chen GC, Chen PC, Huang CS
PubMed: 42983429
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Screening for Parkinson's disease across questionnaires using language models.

Nat Aging. 2026 Nov 4; Epub 2026 Nov 4
Authors:
PubMed: 42983009
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Clinical genetics and genetic counseling in the era of disease-modifying therapies for dementia: lessons from Japan.

J Hum Genet. 2026 Nov 4; Epub 2026 Nov 4
Authors: Nakamura K, Sekijima Y
PubMed: 42982982
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Parkinson's: beyond the brain.

Nature. 2026 Nov 4; Epub 2026 Nov 4
Authors:
PubMed: 42982969
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Physiological APP processing is required for synaptic plasticity and cognition.

Cell Death Dis. 2026 Nov 4;17(1)
Authors: Kilian L, Bengelsdorff V, Just J, Stork S, Galanis C, Banicevic M, Amrein I, Back M, Jungenitz T, Fellenz M, von Engelhardt J, Deller T, Wolfer DP, Vlachos A, Korte M, Müller UC
PubMed: 42982811
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Intergenerational educational attainment and risk for incident dementia in a U.S. community-based cohort study: Findings from the Atherosclerosis Risk in Communities (ARIC) Neurocognitive Study.

J Alzheimers Dis. 2026 Nov 4;:13872877261500432. Epub 2026 Nov 4
Authors: Gupta S, Morrill V, Groechel RC, Kucharska-Newton A, Mosley TH, Lutsey PL, Meza E, Gottesman RF
PubMed: 42982757
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Financial mismanagement leading to genetic diagnosis of familial frontotemporal dementia.

J Formos Med Assoc. 2026 Nov 4; Epub 2026 Nov 4
Authors: Shea YF, Yam KK, Ma W, Chung HB
PubMed: 42982692
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Predicting progression in Parkinson's disease.

J Neurol Neurosurg Psychiatry. 2026 Nov 4; Epub 2026 Nov 4
Authors: Velucci V, Milella G, Vitucci B, Loverre T, De Pizzo F, Carrarini E, Pellicciari R, Iliceto G, Defazio G
PubMed: 42982581
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Human immunodeficiency virus 1 glycoprotein Gp120 induces amyloid pathology in neurons.

Exp Neurol. 2026 Nov 4;408:116108. Epub 2026 Nov 4
Authors: Agbey C, Gamboa A, Wilson K, Campbell LA, Rebeck WG, Nath A, Mocchetti I, NIH-Neuro-HIV Research Consortium
PubMed: 42982399
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HIV-1 Tat drives genotype-dependent neuroimmune programs that promote Parkinson Disease-like neurodegeneration in the hSNCAA53TGba1 mouse model.

Exp Neurol. 2026 Nov 4;408:116107. Epub 2026 Nov 4
Authors: Bertasini C, Lotti V, Lagni A, Grisotto J, Picari R, Diani E, Cecchetto R, Raniero D, Turrina S, Mazzariol A, Gibellini D, Paolone G
PubMed: 42982394
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The Activity Wall in Alzheimer's drug discovery: When potency optimization reaches its limits.

Drug Discov Today. 2026 Nov 4;:104846. Epub 2026 Nov 4
Authors: Ramírez-Márquez CD, Medina-Franco JL
PubMed: 42982364
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Association between functional connectome features and circulating amino acid levels in early-stage Parkinson's disease: An exploratory study.

Neurobiol Dis. 2026 Nov 4;231:107674. Epub 2026 Nov 4
Authors: Esposito F, De Micco R, Nuzzo T, Pirozzi MA, Siciliano M, Hassan A, Cirillo M, Usiello A, Tessitore A
PubMed: 42982204
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P2RX7 drives inflammatory microglia and pathogenic extracellular vesicle secretion in tauopathy.

Neuron. 2026 Nov 4; Epub 2026 Nov 4
Authors: Bodart-Santos V, Ravula AR, You Y, Abdullah M, Ruan Z, Ellison JG, Radhakishun S, Basu Ray N, Melvin BC, Kurti A, Liang Z, Sakai Y, O'Brien DR, Nguyen SN, Shaffer SA, Fiddes L, Butovsky O, Springer W, Ikezu S, Ikezu T
PubMed: 42982039
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Retraction to "Integrative ALS therapy: gene targeted therapy by base editing and potential exercise rehabilitation as synergistic strategies for functional recovery".

Phys Act Nutr. 2026 Nov 4; Epub 2026 Nov 4
Authors: Lee K, Kwak T, Park W
PubMed: 42982035
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Dinotefuran aggravates Alzheimer's disease-associated microglial inflammation through the CHUK/NFKB1-mediated NF-κB signaling pathway.

Neurotherapeutics. 2026 Nov 4;24(1):e01117. Epub 2026 Nov 4
Authors: Baibujiafu G, Lin Y, Zhang L, Du L, Yang S, Yu Y, Ainiwaer K, Luo J, Wang X
PubMed: 42981968
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CSF pTau181 predicts asymmetric hippocampal atrophy in cognitively unimpaired older adults.

J Prev Alzheimers Dis. 2026 Nov 4;13(10):100690. Epub 2026 Nov 4
Authors: Ghanbarian E, Zheng L, Qian T, Glover CM, Sajjadi SA, Corrada MM, Grill JD, Ezzati A, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42981715
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CogniPaz, an Ecologically Oriented Gamified mHealth Tool for Detecting Mild Cognitive Impairment: Prospective Cohort Diagnostic Accuracy Study.

JMIR Mhealth Uhealth. 2026 Nov 4;14:e99688.
Authors: Estebas-Armas C, Medina-López A, Blanco-de-Miguel D, Losantos-García I, Hernández-Barral M, Alonso-López E, Henche-Rodríguez S, Ocampo-Pérez O, Zmork-Martínez GR, Alonso-de-Leciñana M, Frank-García A, Martín-Montes Á
PubMed: 42981698
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Artificial intelligence-based voice biomarkers for early detection and monitoring of neurological diseases: current evidence, limitations, and clinical perspectives.

Comput Biol Med. 2026 Nov 4;218:112041. Epub 2026 Nov 4
Authors: Santiago LR, Kabir IM, Hasbahr VS, Timoteo LM, Tamayo EA, Hadad HR, Muniz LV, Pereira LX, Halim P, Nurkolis F, Syahputra RA, de Azambuja Ribeiro RI
PubMed: 42981649
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Serum Aberrant Expression of Long Non-coding RNA LINC00365 and its Diagnostic Value in Alzheimer's Disease.

J Geriatr Psychiatry Neurol. 2026 Nov 4;:8919887261505040. Epub 2026 Nov 4
Authors: Chen S, Xu N, Shi J, Li D
PubMed: 42981447
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Distinct tau PET dynamics in early versus late age-of-onset Alzheimer's disease.

Sci Transl Med. 2026 Nov 4;18(874):eaea2816. Epub 2026 Nov 4
Authors: Chiotis K, Blazhenets G, Soleimani-Meigooni DN, Aisen PS, Amuiri A, Atri A, Beckett L, Brickhouse M, Clark DG, Dage JL, Day GS, Duara R, Eloyan A, Foroud T, Graff-Radford NR, Grant IM, Hammers DB, Honig LS, Johnson EC, Jones DT, Kirby K, Koeppe R, Kramer JH, Kukull WA, Lagarde J, Leuzy A, Maiti P, Masdeu JC, Mendez MF, Musiek E, Nudelman KN, Onyike CU, Riddle M, Rocha S, Rogalski E, Salloway S, Schonhaut DR, Sha SJ, Shankar R, Taurone A, Thangarajah M, Toga AW, Touroutoglou A, Turner RS, Vemuri P, Wingo TS, Wolk DA, Womack K, Zhang J, Carrillo MC, Dickerson BC, Apostolova LG, La Joie R, Rabinovici GD
PubMed: 42981430
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Cardiorespiratory fitness and risk of incident dementia: systematic review and meta-analysis of 12 cohort studies involving 2.3 million cognitively intact participants.

Geroscience. 2026 Nov 4; Epub 2026 Nov 4
Authors: Kunutsor SK, Taguiam E, Krache M, Laukkanen JA
PubMed: 42980900
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A narrative review of rare variants in Alzheimer's disease: diverse populations inform diverse mechanisms.

Neurol Sci. 2026 Nov 4;47(11)
Authors: Tábuas-Pereira M, Santana I, Kun-Rodrigues C, Paquette K, Brás J, Guerreiro R
PubMed: 42980874
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Modulation of Alzheimer's disease pathogenesis by the FGF-FGFR axis: therapeutic implications and translational perspectives.

Mol Biol Rep. 2026 Nov 4;53(1)
Authors: Saifi A, Bishnoi M, Deshmukh R
PubMed: 42980867
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Clinical correlates of cognitive impairment in progressive supranuclear palsy and multiple system atrophy: a comparative neuropsychological study.

J Neural Transm (Vienna). 2026 Nov 4; Epub 2026 Nov 4
Authors: Athira PM, Kumar KJ, Prasad S, Geethu TV, Harish M, Dey S, Ravichandiran K, Kataria A, Mohan S, Kamble N, Holla VV, Mahale RR, Mailankody P, Mehta A, Binu VS, Pal PK, Yadav R
PubMed: 42980755
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Advances in plant polysaccharide research for neurodegenerative diseases therapy.

Mol Biol Rep. 2026 Nov 4;53(1)
Authors: He BH, Yang W, Yang M, Lv X, Zhao JJ
PubMed: 42980747
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From molecular pathways to nanocarrier design: a translational framework for lipid-based nanoparticles in Alzheimer's disease.

Discov Nano. 2026 Nov 4;21(1)
Authors: Manna P, Maity A, Roy S, Sahu S, Pradhan S, Ganguly SC, Chakraborty M, Kundu M
PubMed: 42980730
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MCU Dysregulation in Alzheimer's Disease: Linking Calcium Overload to Mitochondrial Failure, Neurodegeneration, and Therapeutic Opportunities.

Mol Neurobiol. 2026 Nov 4;63(1)
Authors: Babu HW, Muthukumar S, Lakhanpal V, Wander A, Narayanaswamy A, Reddy DH, Vellingiri B
PubMed: 42980692
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Protein Isoaspartate Repair in Amyotrophic Lateral Sclerosis: An Integrative Bioinformatic Analysis of the PCMT Gene Family.

ACS Chem Neurosci. 2026 Nov 4;17(21):3526-3537.
Authors: Yardimci BI, Zurel AG, Biterge B
PubMed: 42980086
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Conditional Mutant MAPT Overexpression in Neural Organoids Elicits Robust Tau Accumulation and Pathological Transcriptomic Responses.

ACS Chem Neurosci. 2026 Nov 4;17(21):3501-3516.
Authors: Kjar A, Kim H, Spetz MR, Jarrett Z, Fernandez M, Wang J, Russotti ML, Bodnya C, Chavarria D, Hohman TJ, Gama V, Grueter B, Brunger JM, Lippmann ES
PubMed: 42980085
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Hippocampal 5-HT4/6 Receptor Antagonists Normalize Dopaminergic Dysfunction in a Rodent Model of Alzheimer's Disease.

ACS Chem Neurosci. 2026 Nov 4;17(21):3517-3525.
Authors: Eassa NE, Perez SM, Yang OJ, Boley AM, Lodge DJ
PubMed: 42980082
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Causal inference analysis of the effect of amyloid-β and tau proteins on dementia risk: A Mendelian randomization analysis.

J Alzheimers Dis. 2026 Nov 4;:13872877251415494. Epub 2026 Nov 4
Authors: Ayembilla JA, Osagie RO, Akinade AT, Sako O, Ogunmiluyi OE, Awe OI
PubMed: 42979808
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Severe suicidal behavior in the context of unrecognized progressive supranuclear palsy: temporal association with rTMS.

Neurocase. 2026 Nov 4;:1-8. Epub 2026 Nov 4
Authors: George Z, Viktor G, Argyro D, Vasilios C, Evdoxia T
PubMed: 42978546
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Cerebral amyloid PET in obstructive sleep apnoea: a systematic review and exploratory meta-analysis.

Nucl Med Commun. 2026 Nov 4; Epub 2026 Nov 4
Authors: Chiaravalloti A, Schillaci O
PubMed: 42978421
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Corrigendum: Transcriptional programs mediating neuronal toxicity and altered glial-neuronal signaling in a Drosophila knock-in tauopathy model.

Genome Res. 2026 Nov 3;36(11):2399.
Authors: Bukhari H, Nithianandam V, Battaglia RA, Cicalo A, Sarkar S, Comjean A, Hu Y, Leventhal MJ, Dong X, Feany MB
PubMed: 42977496
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CD4+ T cell subsets in CNS disorders: Pathogenic roles, immune dysregulation, and therapeutic perspectives.

Exp Cell Res. 2026 Nov 3;464(1):115219. Epub 2026 Nov 3
Authors: Afkhami H, Yousefi MH, Zarei Taher T, Mahmoudvand G, Rezaei P, Salehi S, Fath-Bayati L, Hosseinzadeh F
PubMed: 42977184
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Survival analysis of spontaneous speech for predicting mild cognitive impairment-to-dementia conversion.

J Prev Alzheimers Dis. 2026 Nov 3;13(10):100692. Epub 2026 Nov 3
Authors: Hinojosa-Calleja A, Calm B, Alegret M, Espinosa A, Cano A, Fernández MV, Miguel A, Solivar A, Valenzuela-Seba A, García-González P, Puerta R, Olivé C, Capdevila-Bayo M, Muñoz-Morales Á, Bayón-Buján P, Rovira-Bruna M, Iza M, Montreal L, Rosende-Roca M, Sanz-Cartagena P, Cantero-Fortiz Y, Gurruchaga MJ, Tarraga L, Montalbán X, Boada M, Ruiz A, Marquié M, Valero S
PubMed: 42976517
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Mitoxyperilysis and mitochondrial quality control in Parkinson's disease: emerging links to autophagy and neuronal death.

Apoptosis. 2026 Nov 3;31(11)
Authors: Tian X, Zhang B, Wei J
PubMed: 42975737
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Dementia imaging in the era of monoclonal anti-amyloid therapies.

Eur Radiol. 2026 Nov 3; Epub 2026 Nov 3
Authors: Barkhof F, Oliveira TG, Vernooij MW
PubMed: 42975710
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Subtype and stage inference of tract-level diffusion abnormalities in amyotrophic lateral sclerosis.

J Neurol. 2026 Nov 3;273(11)
Authors: Yin Y, Tu Y, Wang B, Chen Y, Zhao Y, Tang J, Zhang M, Zhang J
PubMed: 42975660
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Assessing instrumental activities of daily living in people with mild-to-moderate dementia: Objective and subjective assessments and their cognitive correlates.

J Neuropsychol. 2026 Nov 3; Epub 2026 Nov 3
Authors: Martyr A
PubMed: 42975556
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A validated antibody toolbox for ALS research.

Elife. 2026 Nov 3;15
Authors: Ayoubi R, MacDougall EJ, McDowell I, Biddle MS, Ferreira BT, Zha C, Dorion MF, Ross JP, Bolivar SG, Ruiz Moleon V, Alende C, Francis V, Fotouhi M, Chaineau M, Chen CX, Piscopo VE, Soubannier V, Shlaifer I, You Z, Nicouleau M, Keates T, Lee WH, Marsden BD, Koukouflis L, Wigren E, Marks CA, Healy LM, Dion PA, Rouleau GA, Fon EA, Virk HS, Gräslund S, Gileadi O, Edwards AM, Durcan TM, McPherson PS, Laflamme C
PubMed: 42975030
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White matter injury, brain aging, and cognitive decline beyond amyloid/tau.

J Alzheimers Dis. 2026 Nov 3;:13872877261500493. Epub 2026 Nov 3
Authors: Beheshti I, Elkana O
PubMed: 42974819
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Preliminary Psychometric Evaluation of the Korean Version of the Dementia Apraxia Test.

OTJR (Thorofare N J). 2026 Nov 3;:15394492261496846. Epub 2026 Nov 3
Authors: Lee HR, Choi YI
PubMed: 42973402
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Reply: Clarifying incremental accuracy and thresholds for a plasma tau-to-amyloid ratio.

Brain. 2026 Nov 3; Epub 2026 Nov 3
Authors: Benina N, Buitrago L, De Simone FI, Radwan RR, Miller MC, Martin K, Dickson D, Ho S, Moghekar A, Albert M, Mattsson-Carlgren N, Palmqvist S, Ossenkoppele R, Jonsson MF, Hansson O, Stomrud E, Sachdev P, Niu H, Verbel D, Hawkins DM
PubMed: 42973074
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Clarifying incremental accuracy and thresholds for a plasma tau-to-amyloid ratio.

Brain. 2026 Nov 3; Epub 2026 Nov 3
Authors: Wang Z, Chen J
PubMed: 42973061
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Tau-driven hyperexcitability of locus coeruleus noradrenergic neurons underlies sleep fragmentation and cognitive decline in mice.

Cell Rep. 2026 Nov 3;45(11):118273. Epub 2026 Nov 3
Authors: Li W, Tao J, He C, Xiao J, Li M, Xu G, Jia Y, Qin H, Chen X, Wang YJ
PubMed: 42981191
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Brain glucose metabolism and blood brain barrier permeability in Alzheimer's disease continuum.

Aging (Albany NY). 2026 Nov 3;18(1):1494-1514. Epub 2026 Nov 3
Authors: Ricci F, Motta C, Bonomi CG, Bernocchi F, Poli M, Koch G, Chiaravalloti A, Martorana A
PubMed: 42981159
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Progress towards improving mouse models for preclinical testing of treatments for Alzheimer's disease.

Mamm Genome. 2026 Nov 3;37(1)
Authors: Sasner M, Rangel-Barajas C, Oblak AL
PubMed: 42980691
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The Effect of Alzheimer's Disease and Diabetes on the Volume of Brain Structures.

J Vis Exp. 2026 Nov 3;(237)
Authors: Arpacı MF, Akçiçek M, Uzun GB, İnceoğlu F, Altıparmak A, Deniz MA, Bolayır A, Aygül G, Pekmez H, Acer N
PubMed: 42980257
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Gut-Induced Synuclein Propagation: A New Mechanism in Neurodegenerative Disease.

Neuroscientist. 2026 Nov 3;:10738584261490909. Epub 2026 Nov 3
Authors: Sun Y, Li B, Ye K
PubMed: 42978412
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Tractography-Based Insights into Neuroplasticity and Clinical Heterogeneity in Parkinson's Disease Subtypes.

Neuroscientist. 2026 Nov 3;:10738584261497262. Epub 2026 Nov 3
Authors: Kar P, Roy D, Kar BR
PubMed: 42978407
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Methods for Identification and Structural Characterization of Tau Polymorphs in Neurodegenerative Disease.

Biophys J. 2026 Nov 3; Epub 2026 Nov 3
Authors: Pitz ME, Mickol RL, Pyles CG, Brown SM, Fidler AP, Fears KP, Beasley MA
PubMed: 42978226
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Lower recorded prevalence of Alzheimer's disease in natalizumab-exposed older adults with multiple sclerosis: A hypothesis-generating observation.

Mult Scler. 2026 Nov 3;:13524585261499995. Epub 2026 Nov 3
Authors: Shirani A, Stopschinski BE, Herz J, Calvier L, Stuve O
PubMed: 42978183
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Vasomechanic treatment is associated with increased efflux of human brain proteins.

Nat Commun. 2026 Nov 3;17(1)
Authors: Tuunanen J, Hautamäki K, Väyrynen T, Järvelä M, Korhonen V, Huotari N, Kaakinen M, Kananen J, Helakari H, Raitamaa L, Jukkola J, Herukka SK, Laurén K, Salmi U, Eklund L, Nikkinen J, Nedergaard M, Kiviniemi V
PubMed: 42977753
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Non-invasive oral magnetoelectric vagus nerve neuromodulation for Parkinson's disease therapy.

Nat Biomed Eng. 2026 Nov 3; Epub 2026 Nov 3
Authors: Mac CH, Chang PJ, Chu LA, Lin YH, Wang JT, Lin CY, Yuan YC, Yao Y, Nguyen DT, Chang Y, Chen YH, Nguyen MT, Lin YJ, Sung HW
PubMed: 42977739
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Nanobody-Modified Outer Membrane Vesicles Attenuate Alzheimer's Disease-Like Neurodegeneration by Modulating Mitophagy-Associated Phenotypes and cGAS-STING-Related Inflammatory Signaling.

Adv Healthc Mater. 2026 Nov 2; Epub 2026 Nov 2
Authors: Xiao J, Yang Z, Li J, Xiong Q, Xia X, Hao L, Ling Z, Pang K, Zhou C, Wu H
PubMed: 42971925
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Genetics of Parkinson's disease and parkinsonism: a practical guide to assessment and testing.

Pract Neurol. 2026 Nov 2; Epub 2026 Nov 2
Authors: Frost JL, Mullane G, Lam E, Real R, Lynch T, Morris HR, Olszewska DA
PubMed: 42971770
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Molecular descriptor-based QSAR modeling of carbamate derivatives for predicting acetylcholinesterase inhibitory activity.

Chem Biol Interact. 2026 Nov 2;441:112412. Epub 2026 Nov 2
Authors: Hosseini F, Ashengroph M, Alaei L
PubMed: 42971381
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Disentangling reproductive history and parenthood in late-life cognitive and vascular brain health.

Neurosci Biobehav Rev. 2026 Nov 2;192:107075. Epub 2026 Nov 2
Authors: Pan Y, Yang R, Xu Y, Zhang H
PubMed: 42971340
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VR Scout for AD: An Immersive Virtual Reality System towards Early Screening of Alzheimer's Disease.

IEEE Trans Vis Comput Graph. 2026 Nov 2;PP Epub 2026 Nov 2
Authors: Ding D, Yao H, Yan H, Huang J, Zhang R, Sun H, Wu T, Liu Y
PubMed: 42970657
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Racial and Ethnic Differences in Access to Alzheimer Special Care Units After Hospitalization.

JAMA Netw Open. 2026 Nov 2;9(11):e2643623.
Authors: Xu H, Bowblis JR, Li S, Pappadis MR, Kuo YF, Goodwin JS
PubMed: 42970288
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ADInteractome: discovering Alzheimer's disease-associated gene interactions from single-nucleus RNA-seq data through neural interaction states.

Brief Bioinform. 2026 Nov 2;27(6)
Authors: Wu Y, Maurya N, Yang Y, Chen W, Wang G, Liu Z, Hu X, Zheng WJ, Xu Z
PubMed: 42969854
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Proteomics Reveals Blood-Brain Barrier Membrane Protein Remodeling in Amyloid-β Pathology.

Mol Pharm. 2026 Nov 2;23(11):5848-5862.
Authors: Hyvärinen J, Todorovska R, Palacios MD, Gynther M, Afonin A, Lehtonen M, Auriola S, Saveleva L, Kanninen KM, Fricker G, Puris E
PubMed: 42969705
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Iron Boride Nanostructures as Oral Acid-Responsive Hydrogen Donors for Alzheimer's Disease Therapy.

Mol Pharm. 2026 Nov 2;23(11):5288-5304.
Authors: Chen Z, Chen D, Zhang J, Wang C, Liu J, Liang Y, He Q, Du X
PubMed: 42969693
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A rare TMEM175 mutation drives Parkinson's disease pathology by disrupting proton gating and lysosomal acidification.

J Clin Invest. 2026 Nov 2;136(21) Epub 2026 Nov 2
Authors: Yang X, Li P, Lv M, Wang L, Shan R, Jiang Z, Chen D, Huang F, Cai W, Zhao L, Guo Z, Chen X, Cen Z, Wang Y, Yang W, Li X, Luo W, Yang L, Hu M, Xu H
PubMed: 42969231
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Former versus current smoking among older adults living with Alzheimer's disease, related dementias, and cognitive impairment.

J Alzheimers Dis. 2026 Nov 2;:13872877261500405. Epub 2026 Nov 2
Authors: Parker MA, Klopack ET, Johnson AL, Guo L, Parker ES
PubMed: 42969191
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Understanding the Pattern of Cognitive Decline in GBA1-Related Parkinson's Disease: An Exploratory Longitudinal Multi-Cohort Study.

Ann Neurol. 2026 Nov 2; Epub 2026 Nov 2
Authors: Bode M, Pauly C, Jónsdóttir SR, Schulte C, Becker S, Wurster I, Roeben B, Lerche S, Poewe W, Krüger R, Liepelt-Scarfone I, Brockmann K, NCER‐PD consortium, Parkinson's Progression Markers Initiative
PubMed: 42969188
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Retinal Microvascular Alterations Link Astroglial Activation to Neurodegeneration in Mild Cognitive Impairment.

Transl Vis Sci Technol. 2026 Nov 2;15(11):5.
Authors: Hu S, Wang Y, Wang L, Wu S, Zheng C, Xu H, Kwapong WR, Wang Z
PubMed: 42975098
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New hemiaminal ether dihydropyrimidinones as CK1/CK2 inhibitors targeting α-synuclein in Parkinson's disease.

RSC Adv. 2026 Nov 2; Epub 2026 Nov 2
Authors: Wakeel H, Munir S, Gondal HY, Cheema ZM, Muskan A, Malik I, Nisar M, Siddiqui H, Sultan SK
PubMed: 42974366
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The cassette exons of α-synuclein play distinct roles in membrane remodelling and membrane-mediated amyloid formation.

Chem Sci. 2026 Nov 2; Epub 2026 Nov 2
Authors: Dewison KM, Chakraborty P, Brockwell DJ, Radford SE
PubMed: 42974245
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Microglia: Metabolic Adaptation in Neurodegeneration.

Neuroscientist. 2026 Nov 2;:10738584261498171. Epub 2026 Nov 2
Authors: Aljayousi L, Gentile N, Ayata P
PubMed: 42973161
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A Multimodal Nomogram Predicting the Risk of Cognitive Impairment in Parkinson Disease.

Mov Disord Clin Pract. 2026 Nov 2; Epub 2026 Nov 2
Authors: Negida A
PubMed: 42972958
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Amyloid beta governs mitochondrial lipid metabolism defects and neurodegenerative lysosomal stress.

EMBO Rep. 2026 Nov 2; Epub 2026 Nov 2
Authors: Walton C, Oleinik N, Kassir MF, Lee HG, Bhat NR, Sambamurti K, Albayram O, Angel P, Wang GY, Bose RJ, Ha K, McCarthy JR, Ogretmen B
PubMed: 42972106
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Flower isoforms mediate fitness selection of astrocytes through extracellular vesicles.

EMBO Rep. 2026 Nov 2; Epub 2026 Nov 2
Authors: Tu SM, Lin CH, Liu Y, Schirra C, Yang CA, Hohneck J, Jung M, Clemenz A, Rother S, Aljohmani A, Yildiz D, Schwarz Y, Krause E, Schulz-Schaeffer WJ, Flockerzi V, Yao CK, Chang HF
PubMed: 42972105
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Digital-like contamination in the Clock Drawing Test: Norms across six scoring systems.

J Neurol Sci. 2026 Nov 2;491:126239. Epub 2026 Nov 2
Authors: Ilardi CR, Osiurak F, Gamboz N, Iavarone A, Scuotto C, Marangolo P, Brandimonte MA, De Luca M, Garofalo E, Federico G
PubMed: 42987555
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A versatile multi-dimensional ratiometric sensor exploiting material-interface properties for t-Tau protein detection in human serum.

Talanta. 2026 Nov 2;314:130895. Epub 2026 Nov 2
Authors: Yuan W, Jin Q, Rong R, Wang X, Wang X, Wang X
PubMed: 42987521
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Protein adduction by multiple aldehydes contributes to α-synuclein aggregation and dopaminergic neuron loss in rat models of Parkinson's disease.

Redox Biol. 2026 Nov 2;98:104468. Epub 2026 Nov 2
Authors: Chen L, Deng H, Li N, He Y, Zhai G, Pan H, Fang C, Shi F
PubMed: 42981985
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Evaluation of cross-cohort generalizability of machine learning-derived blood transcriptomic biomarkers for Parkinson's disease.

Biochem Biophys Res Commun. 2026 Nov 2;842:154828. Epub 2026 Nov 2
Authors: Kumar S
PubMed: 42981817
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Evaluating ANO6 as a Parkinson's disease candidate gene: A human genetic investigation of common and rare variant associations.

Parkinsonism Relat Disord. 2026 Nov 2;153:109027. Epub 2026 Nov 2
Authors: Parlar SC, Leonard H, Senkevich K, Liu L, Teferra M, Global Parkinson's Genetics Program (GP2). Electronic address: cornelis.blauwendraat@nih.gov, Gan-Or Z
PubMed: 42981733
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Exome Sequencing Identifies Population-Specific Genetic Risk Factors for Progressive Supranuclear Palsy in Asia.

Mov Disord. 2026 Nov 1; Epub 2026 Nov 1
Authors: Chen PS, Lin RJ, Chen HY, Cheng L, Hung MZ, Lee NC, Hsu JS, Fan SP, Li CH, Tai CH, Luo W, Zheng X, Chiang HL, Chen CY, Wu YR, Lee TL, Chang YY, Lan MY, Chang HC, Lu CS, Huang SY, Kim HJ, Lee JY, Shin JH, Saranza G, Nomura T, Yaguchi H, Lee WP, Toh TS, Tay YW, Ahmad-Annuar A, Ooi JC, Chia YK, Anuar AN, Ng AS, Tan YJ, Tan AH, Tan EK, Chan CC, Yabe I, Lim SY, Lin CH
PubMed: 42967813
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Targeting RIPK1-NF-κB crosstalk: A novel perspective on necroptosis in Alzheimer's Disease.

Mol Biol Rep. 2026 Nov 1;53(1)
Authors: Kartik S, Rohilla K, Pal R
PubMed: 42967243
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Corrigendum to "Neurodegenerative mortality among National Football League Players".

EClinicalMedicine. 2026 Nov;101:104276. Epub 2026 Oct 24
Authors: Luster CB, Abdolmohammadi B, Mastrodicasa MJ, Nowinski CJ, Feigel ED, Finegan B, White AJ, Connors EJ, Rovito C, Zafonte RD, Alosco ML, McKee AC, Mez J, Daneshvar DH
PubMed: 42964555
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A multimodal digital NeuroMarker platform with composite and domain-level validity for identification of mild cognitive impairment: a cross-sectional study.

EClinicalMedicine. 2026 Nov;101:104266. Epub 2026 Oct 23
Authors: Iulita MF, Kolachalama VB, Brugada-Ramentol V, Harrison J, Griffin N, Benavides GS, Vera-Campuzano E, Minguillon C, Alcolea D, Mackintosh L, Ward L, Merino AT, Balasa M, Ishida S, Rivera OG, Calvet MS, Robertson J, Doecke J, Mas CP, Fallone S, Charvat M, Tarnanas I, Jones M, Streel E
PubMed: 42964515
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Integrative Evolutionary and Structural Analysis of GBA1 Provides Insights Into Mutation-Specific Effects Associated With Parkinson's Disease.

Eur J Neurosci. 2026 Nov;64(9)
Authors: Mustafa S, Abbasi AN, Mughal KA, Batool F, Malik MF, Khalid RR, Abbasi AA, Bao Y
PubMed: 42963316
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Navigating the Challenges of Shared Decision-Making in Amyloid Immunotherapy for Alzheimer's Disease.

Eur J Neurol. 2026 Nov;33(11)
Authors: François G, Michalon R, Tannou T, Damier P, Desmoulin S, Lebouvier T
PubMed: 42969459
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Frontal Cerebral Blood Flow Deficits in Behavioral Variant Frontotemporal Dementia: Associations With Clinical Symptoms, Peripheral Vascular Biomarkers, and Neuroimaging Measures.

CNS Neurosci Ther. 2026 Nov;32(11)
Authors: Hou J, He Q, Fu X, Chen Y, Lu H, Xu Y, Wu L, Chu M
PubMed: 42968588
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Beyond the Microbial Hypothesis: Shared Genetic, Osteoimmune and Vascular Mechanisms in the Oral-Brain Axis Linking Periodontitis and Alzheimer's Disease.

Eur J Neurosci. 2026 Nov;64(9)
Authors: Kabbashi S, Ahmed M, Chetty M
PubMed: 42968523
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Sleep Dysfunction as a Unifying Theme in Dementia.

J Sleep Res. 2026 Nov 1; Epub 2026 Nov 1
Authors: Jiang J, Larsen EK, Warren JD
PubMed: 42968428
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Evaluating plasma phosphorylated tau217 for clinical rule-out of cerebral amyloid pathology: Evidence from a memory clinic cohort.

J Alzheimers Dis. 2026 Nov 1;:13872877261500407. Epub 2026 Nov 1
Authors: Kurz CI, Tegethoff P, Hufnagel A, Perneczky R
PubMed: 42968340
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Dry, but not wet, age-related macular degeneration increases Alzheimer's disease risk: Findings from a multidimensional analysis.

J Alzheimers Dis. 2026 Nov 1;:13872877261502863. Epub 2026 Nov 1
Authors: Yang L, Zeng J, Ding Y, Li L
PubMed: 42968295
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Integrated clinical and transcriptomic analysis reveals miRNA-mediated mechanisms linking hearing loss to cognitive decline in Alzheimer's disease.

J Alzheimers Dis. 2026 Nov 1;:13872877261501149. Epub 2026 Nov 1
Authors: Wang X, Zhang B, Ma H, Shan A, Lian Q, Han X, Xu C, Yao Q, Wen B, Luan H, Li S, Cui T, Lv S, Sun Q, Guo J, Chen R, Wei C
PubMed: 42968239
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Eyes-open resting-state EEG microstate analysis using ratio-normalized parameters across four- and seven-class solutions in healthy controls, mild cognitive impairment, and Alzheimer's disease.

J Alzheimers Dis. 2026 Nov 1;:13872877261501861. Epub 2026 Nov 1
Authors: Simfukwe C, An SS, Youn YC
PubMed: 42968018
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Mitochondria-Associated Membranes as a Convergent Hub of Brain Aging: From Neurodegeneration to Cerebral Ischemia.

Eur J Neurosci. 2026 Nov;64(9)
Authors: Li M, Xu D, Li Y, Zhao Q
PubMed: 42977507
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Beyond the Brain: Understanding the Dermatologic Associations of Neurodegenerative Diseases.

J Drugs Dermatol. 2026 Nov 1;25(11):1080-1081.
Authors: Zarghami A, Khakh A, Nussbaum D, Friedman A
PubMed: 42976824
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Dextromethorphan as a Potentially Safer Treatment for Agitation Associated With Dementia Due to Alzheimer's Disease.

J Psychosoc Nurs Ment Health Serv. 2026 Nov;64(11):6-8. Epub 2026 Nov 1
Authors: Kverno K
PubMed: 42976263
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Transcranial Pulse Stimulation in Parkinson's Disease: A Systematic Review.

Brain Behav. 2026 Nov;16(11)
Authors: Pereira GS, Rosa GH, Neto PA, de Araújo JE, da Silva ML
PubMed: 42975199
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Clock Drawing Test Performance in Rural Vietnam: Reliability and Concurrent Validity Relative to the Mini-Mental State Examination in a Community-Based Sample.

Geriatr Gerontol Int. 2026 Nov;26(11)
Authors: Yazawa A, Pham TT, Nguyen CQ, Ito A, Phan DC, Hachiya M, Hoang TT, Do HT, Mizoue T, Inoue Y
PubMed: 42974696
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Misfolded tau propagates via templated seeding.

Nat Neurosci. 2026 Nov;29(11):2625.
Authors: Ren Q
PubMed: 42972096
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A brain of many microglia origins.

Nat Neurosci. 2026 Nov;29(11):2625.
Authors: Marin IA
PubMed: 42972093
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Differential NMDA-Evoked Excitatory and Inhibitory Neuronal Responses Under In Vivo and Ex Vivo Conditions in 5xFAD Mice.

Eur J Neurosci. 2026 Nov;64(9)
Authors: Lee S, Park T, Chung SW, Suh M
PubMed: 42988526
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Matrix Matters: Head-To-Head Concordance of Serum and Plasma for NULISAseq CNS Disease Panel.

J Neurochem. 2026 Nov;170(11)
Authors: Merati T, Tolassi C, Rondina A, Girotto I, Bertoni M, Sweeney EM, Toja A, Rusi E, Martinuzzo C, Pilotto A, Padovani A
PubMed: 42985912
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Alzheimer's Disease: Mechanisms and Therapeutic Advances.

MedComm (2020). 2026 Nov;7(11):e71093. Epub 2026 Nov 3
Authors: Fu G, Pan M, Sun Q, Yue G, Lei T
PubMed: 42985466
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Determinants of time from symptom debut to dementia diagnosis in United Arab Emirates.

BJPsych Int. 2026 Nov;23(4):212-219. Epub 2025 Nov 20
Authors: Javaid SF, Alkuwaiti S, Ibrahim N, Alkaabi F, Al Houqani S, Al Mugaddam F, Abdel Aziz K, Andrade G, Shebani Z
PubMed: 42985407
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Cognitive screening in Egypt: survey of opinions and best practices for detecting cognitive impairment in Egyptians.

BJPsych Int. 2026 Nov;23(4):222-227. Epub 2026 Jan 22
Authors: Berry J, Berry J, Nasreddine Z, Loza N, Boulos K
PubMed: 42985403
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Intrathecal Transplantation of Human Umbilical Cord-Derived MSCs Outperforms Intravenous Administration in Attenuating Pathology and Cognitive Deficits in Alzheimer's Disease Mice.

CNS Neurosci Ther. 2026 Nov;32(11)
Authors: Ding L, Yu W, Chen Y, Wang H, Li S, Li H, Shu T, Huang X, Yang Y, Liu R, Liu X, Ai Z, Guo X, Chen J, Qu Q
PubMed: 42984124
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Evaluating the accuracy of brief cognitive assessments for the early detection of cognitive impairment in adults across primary and specialty care settings: A systematic review and meta-analysis.

Alzheimers Dement. 2026 Nov;22(11)
Authors: Loveless J, Pilcher L, Bolton CJ, Guan DX, Imo U, Ngubo CG, McAteer MB, Urquhart O, Rangarajan SK, Kim LS, Sako K, Tang B, Yakoub Y, Machado LS, Ko F, Rentz D, Pahlke S, Mahinrad S, Snyder H, Tampi MP
PubMed: 42983912
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How a once-controversial idea is advancing understanding of Parkinson's disease.

Nature. 2026 Nov;659(8139):S9-S11.
Authors: Nuwer R
PubMed: 42983047
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How the brain protects itself from Parkinson's disease.

Nature. 2026 Nov;659(8139):S14-S15.
Authors: DeWeerdt S
PubMed: 42983045
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Could chemicals contribute to Parkinson's?

Nature. 2026 Nov;659(8139):S12-S13.
Authors: Worth T
PubMed: 42983044
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Replacing the neurons that Parkinson's destroys.

Nature. 2026 Nov;659(8139):S2-S4.
Authors: Dattaro L
PubMed: 42983043
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Six highlights from Parkinson's disease research.

Nature. 2026 Nov;659(8139):S16-S17.
Authors: Nuwer R
PubMed: 42983042
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Progress accelerates in Parkinson's treatments.

Nature. 2026 Nov;659(8139):S1.
Authors: Brody H
PubMed: 42983040
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The shared genetic architecture of the TDP-43 spectrum: Bridging clinical FTLD and neuropathological endophenotypes.

Alzheimers Dement. 2026 Nov;22(11)
Authors: Patel M, Kumar P, Western D, Johnson M, Liu M, Budde J, Cruchaga C, Pottier C
PubMed: 42982761
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Locus coeruleus microstructural integrity and sleep disruption in the context of Alzheimer's disease pathology.

Alzheimers Dement. 2026 Nov;22(11)
Authors: Van Egroo M, Patsyuk Y, Baillet M, Vogt NM, Lim AS, Ashton NJ, Janelidze S, Blennow K, Hansson O, Zetterberg H, Jacobs HI
PubMed: 42982755
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Validation of plasma biomarker immunoassay-based models for predicting brain amyloid positivity in cognitively impaired individuals.

Alzheimers Dement. 2026 Nov;22(11)
Authors: Syrjanen JA, Figdore DJ, Griswold ME, Wiste HJ, Dierkhising RA, Kremers WK, Lachner C, Graff-Radford NR, Day GS, Graff-Radford J, Jack CR Jr, Knopman DS, Petersen RC, Bornhorst JA, Algeciras-Schimnich A, Alzheimer's Disease Neuroimaging Initiative
PubMed: 42982748
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Measurement precision matters: Accounting for uncertainty alters estimated memory trajectories across the cognitive spectrum.

Alzheimers Dement. 2026 Nov;22(11)
Authors: Trittschuh EH, Scollard P, Crane PK, Choi SE, Mez J, Saykin AJ, Gibbons LE, Mukherjee S
PubMed: 42982742
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Accelerated clinical evaluations for Alzheimer's disease: feasibility across specialty and rural care settings.

Alzheimers Dement. 2026 Nov;22(11)
Authors: Vidoni ED, Morris JK, Weis K, Townley RA, Parks AC, Brunette AM, Gillen LR, Fikru SA, Montero A, Brubaker R, Woodall D, Agee S, Summers K, Levendovszky SR, Davis D, Woodward JL, Burns JM
PubMed: 42982740
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Stable episodic memory and higher education do not influence the rate of Alzheimer's disease pathology as measured by plasma p-tau217.

Alzheimers Dement. 2026 Nov;22(11)
Authors: Avelar-Pereira B, Spotorno N, Dolado AO, Bali D, Adolfsson AN, Mattsson-Carlgren N, Palmqvist S, Janelidze S, Hansson O, Nyberg L
PubMed: 42982738
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Correction to "Gamma sensory stimulation in mild Alzheimer's dementia: An open-label extension study".

Alzheimers Dement. 2026 Nov;22(11)
Authors:
PubMed: 42982612
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Clinical Trajectory of Late-Onset Delusional Disorder Toward Evolving Dementia With Lewy Bodies.

Psychogeriatrics. 2026 Nov;26(6)
Authors: Fujishiro H, Takeda K, Iwata-Endo K, Arafuka S, Miyata S, Iwamoto K, Torii Y, Iritani S
PubMed: 42980247
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Coptis chinensis rhizome extract up-regulates ATP13A2 and lysosomal function to reduce neuronal vulnerability in α-synuclein-expressing BE(2)-M17 cells.

J Tradit Complement Med. 2026 Nov;16(6):654-667. Epub 2026 Sep 9
Authors: Lin CH, Wu YR, Chao CY, Chen CM, Chen IC, Lee-Chen GJ, Chang KH
PubMed: 42979290
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A comprehensive review of the two most commonly studied traditional Chinese medicines for treating Alzheimer's disease.

J Tradit Complement Med. 2026 Nov;16(6):573-583. Epub 2026 Sep 19
Authors: Shiao YJ
PubMed: 42979024
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Cross-Organ Multi-Omics Profiling of Systemic Alterations in 5xFAD Mice and Changes Associated with Huanglian Jiedu Decoction Treatment.

Adv Sci (Weinh). 2026 Oct 31; Epub 2026 Oct 31
Authors: Gao W, Gao J, Su X, Kong X, Wei X, Ding T, Guo T, Gao S, Zhou Y, Zhou J, Zhao H
PubMed: 42966893
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Safety and efficacy of cannabinoid-based interventions in Parkinson's disease: A frequentist and bayesian meta-analysis of randomized controlled trials.

Rev Neurol (Paris). 2026 Oct 31; Epub 2026 Oct 31
Authors: Fernandes JV, Tudella GC, Klostermann AU, Menegucci G, de Almeida KJ
PubMed: 42966680
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Biological mechanisms of ageing and potential therapeutic targets.

Med Clin (Barc). 2026 Oct 31;:107678. Epub 2026 Oct 31
Authors: Rius-Bonet J, Abbas M, Macip S
PubMed: 42966663
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Iron affects association and dissociation rates of α-synuclein iron-responsive element mRNA binding to iron regulatory protein in Parkinson's disease.

Int J Biol Macromol. 2026 Oct 31;386:155071. Epub 2026 Oct 31
Authors: Khan MA, Mohammad T, Khan N, Shaibah HS, Hassan MI
PubMed: 42966587
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Current development of therapeutic strategies for Alzheimer's disease.

Am J Med. 2026 Oct 31; Epub 2026 Oct 31
Authors: Goetzl EJ
PubMed: 42966519
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Dendrobium officinale extract ameliorates Alzheimer's disease by modulating PI3K-AKT-mTOR pathway and autophagy-related processes: An integrated study combining feature-based molecular networking, network pharmacology and multi-omics.

J Ethnopharmacol. 2026 Oct 31;374(Pt 3):122588. Epub 2026 Oct 31
Authors: Fu J, Liang Z, Wang F, Xiong F, Wang X, Sun J, Zhan J, Hu K, Gao H
PubMed: 42966516
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SIRT1 signaling in Alzheimer's disease: Regulation of mitochondrial biogenesis and therapeutic implications.

Pharmacol Res. 2026 Oct 31;234:109713. Epub 2026 Oct 31
Authors: Liu D, Li P, Gao Q, Liu B, Li W, Liu X
PubMed: 42966483
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Nanomedicine for Alzheimer's disease: A stage-matched framework integrating pathological network modulation, blood-brain barrier delivery, and clinical translation.

Pharmacol Res. 2026 Oct 31;234:109709. Epub 2026 Oct 31
Authors: Li J, Wang Y, Liu Y, Ji Y, Lu P, Yang W, Zhang S
PubMed: 42966482
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Reduced BNIP1 impairs autophagosome-lysosome fusion in hippocampal neurons and contributes to Alzheimer's disease pathology.

Brain Res Bull. 2026 Oct 31;246:112186. Epub 2026 Oct 31
Authors: Li C, Zhang M, Xia H, Zhi X, Wang N, Guo J, Wang K, Wang L, Wang X, Zhang W
PubMed: 42966413
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Intracerebral Administration of a Novel, Bioactive Peptide Induces a Biochemical Profile in Rat Brain Reminiscent of Alzheimer's Disease.

Neurochem Res. 2026 Oct 31;51(6)
Authors: Watkinson B, Bast T, Williams S, Bourgade K, Garcia-Rates S, Hasan S, Greenfield S
PubMed: 42965728
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Revealing Pharmacological Target for Comorbid Epilepsy in Alzheimer's Disease: Neurochemical Insights from STZ Mice.

Neurochem Res. 2026 Oct 31;51(6)
Authors: Kaur A, Goel RK
PubMed: 42965717
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Leveraging immunoprecipitation mass spectrometry and neuropathology to identify the clinical value of different blood tau species in Alzheimer's disease.

J Neurol. 2026 Oct 31;273(11)
Authors: Labonte J, Miner AE, Groh JR, Montoliu-Gaya L, Tripodis Y, Aparicio HJ, Turk KW, Budson AE, Farrer L, Goldstein LE, Qiu WQ, Mez J, McKee AC, Zetterberg H, Stein TD, Gobom J, Ashton NJ, Alosco ML
PubMed: 42965704
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AI-based diagnosis of frontotemporal dementia using neuroimaging: a systematic review and meta-analysis.

Eur Radiol. 2026 Oct 31; Epub 2026 Oct 31
Authors: Li Y, He X, Li N, Luo X
PubMed: 42965691
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Correction to: Rapamycin restores peripheral blood flow in aged mice and in mouse models of atherosclerosis and Alzheimer's disease.

Geroscience. 2026 Oct 31; Epub 2026 Oct 31
Authors: Van Skike CE, DeRosa N, Galvan V, Hussong SA
PubMed: 42965647
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Protein Quality Control Systems in Neurodegeneration-Chaperones, Cytoskeleton, and the Pathogenic Transition of Tau.

Mol Neurobiol. 2026 Oct 31;63(1)
Authors: Bisht A, Pippadpally S, Kumar V
PubMed: 42965640
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MetaDome 2027: a comprehensively updated resource for aggregating missense variant evidence across homologous human protein domains.

Nucleic Acids Res. 2026 Oct 31; Epub 2026 Oct 31
Authors: Wiel L, Ferraro F, Yu J, Zhen J, Nachun D, Mendez R, Reuter CM, Cui JL, Bonner DE, Carter JN, Marwaha S, van de Vorst M, Emami S, Kravets E, Neu MB, van Ham TJ, Kleefstra T, Ashley EA, Bernstein JA, Montgomery SB, Gilissen C, Wheeler MT
PubMed: 42963945
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Tau positron emission tomography imaging in progressive supranuclear palsy: A review of phenotypes, symptoms, and clinical severity.

Parkinsonism Relat Disord. 2026 Oct 31;:109039. Epub 2026 Oct 31
Authors: Chow CM, Rosal AE, Camastra C, Strafella AP
PubMed: 42977585
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Disrupted imagery, disrupted scenes: mental scene construction in behavioural-variant frontotemporal dementia.

Brain Res. 2026 Oct 30;1895:150621. Epub 2026 Oct 30
Authors: El Haj M, Chapelet G, Kapogiannis D, Boutoleau-Bretonnière C
PubMed: 42962989
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The metabolic-brain axis: GLP-1 signaling, insulin resistance, and obesity pharmacotherapy in neurodegeneration.

Metabolism. 2026 Oct 30;186:156810. Epub 2026 Oct 30
Authors: Santerre M, Shcherbik N, Sawaya BE
PubMed: 42962966
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Targeting lipid peroxidation-derived aldehydes in Parkinson's Disease and ageing: Antioxidant investigations and mechanistic insights.

Ageing Res Rev. 2026 Oct 30;123:103432. Epub 2026 Oct 30
Authors: Nicoara C, Fezza F, Maccarrone M, Bartolacci A, Guescini M, Marchegiani F, Campagna R, Picconi B, Stocchi F, Stocchi V, De Pandis MF, Donati-Zeppa S, Rotondo R
PubMed: 42962772
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Metabolic endotyping for mechanism-informed Alzheimer's and Parkinson's disease trials.

Med. 2026 Oct 30;:101336. Epub 2026 Oct 30
Authors: Santiago JA, Rascol O, Foltynie T, Meissner WG, Potashkin JA, Gutierrez-Silva JC, Shahrestani MN, Wu Y, Rundek T, Haq IU
PubMed: 42962668
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The neurobiology of menopause: Implications for brain aging and Alzheimer's risk.

Neuron. 2026 Oct 30; Epub 2026 Oct 30
Authors: Mosconi L
PubMed: 42962664
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Age-dependent structural evolution of a functional amyloid contributes to memory impairment in Drosophila.

Cell. 2026 Oct 30; Epub 2026 Oct 30
Authors: Ou S, Guillen-Poza PA, Ng KK, Xu L, Cheng BY, Yi Y, Ho LY, Franco-Fernández A, Khaki PS, Mukhi M, Cheung KC, Sharma R, Oroz J, Hirano Y, Hervas R
PubMed: 42962658
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Manganese exposure activates the cGAS-STING-IL-17 axis and is associated with Tau and α-synuclein accumulation in mice.

Ecotoxicol Environ Saf. 2026 Oct 30;326:120992. Epub 2026 Oct 30
Authors: Yang J, Luo J, Zhou Q, Chai X, Wang X, Li J, Wang M, Gu X, Chang X, Li S, Yang M, Sun Y, Wang H
PubMed: 42962470
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LAMP2A gene therapy mitigates Parkinson's disease-related pathology in nonhuman primates.

Sci Adv. 2026 Oct 30;12(44):eaeg1787. Epub 2026 Oct 30
Authors: Arotcarena ML, Fouka M, Gialinaki EG, Giannopoulou M, Jadot H, Darricau M, Lovisotto A, Dovero S, Planche V, Balpe E, Achour M, Thiolat ML, Dutheil N, Li Q, Noe E, Pioli EY, Harhouri K, Steinschneider R, Kirik D, Jensen NM, Jensen PH, Stefanis L, Bezard E, Dehay B, Xilouri M
PubMed: 42962009
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Heat-Killed Lactobacillus murinus Attenuates Aβ25-35-Induced Neurotoxicity and Alters Hippocampal 6-Phosphogluconate Metabolism.

Probiotics Antimicrob Proteins. 2026 Oct 30; Epub 2026 Oct 30
Authors: Li D, Ding G, Sun Z, Qian Y, Zhang W, Wang G, Zhang F
PubMed: 42961718
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Cost-Effectiveness Analysis of Disease-Modifying Therapies for Early Alzheimer's Disease in China.

Neurol Ther. 2026 Oct 30; Epub 2026 Oct 30
Authors: Dong S, Gao K, Lin W, Chen W, Liu H, Wang Q, Yi Z
PubMed: 42961631
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Delayed associative memory and recall error patterns in mild cognitive impairment: discriminant capacity of the Italian face-name association test.

Geroscience. 2026 Oct 30; Epub 2026 Oct 30
Authors: Scaramuzzi GF, Ventrella T, Iacobellis S, Lonigro L, Gasparre D, Taurisano P, Manippa V
PubMed: 42961537
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From dosage alteration to amplification strategies: mechanistically defined alpha-synuclein mouse models for Parkinson's disease therapy development.

Acta Neuropathol. 2026 Oct 30;152(1)
Authors: Nuber S, Fanning S, Dettmer U
PubMed: 42961519
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Annual Dementia Incidence May Reach 25 Million by 2050.

JAMA. 2026 Oct 30; Epub 2026 Oct 30
Authors: Richmond S
PubMed: 42961441
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Alpha-synuclein: The main actor at the first Patagonia Synuclein workshop.

J Parkinsons Dis. 2026 Oct 30;:1877718X261494920. Epub 2026 Oct 30
Authors: Fernández Outón CO, Do Carmo Gonçalves P, Fernández I, Outeiro TF
PubMed: 42961317
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Cerebrospinal fluid p62/SQSTM1 is associated with tau pathology, brain structural alterations, and cognitive impairment in adults without dementia.

J Alzheimers Dis. 2026 Oct 30;:13872877261502791. Epub 2026 Oct 30
Authors: Yao MY, Guo HH, Li QY, Huang LY, Tan L, Wang HF, Alzheimer's Disease Neuroimaging Initiative
PubMed: 42961137
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Draw me a zebra: Study of an item-drawing protocol to assess semantic memory in a memory clinic.

J Alzheimers Dis. 2026 Oct 30;:13872877261502808. Epub 2026 Oct 30
Authors: Dissard M, Deheinzelin L, Ouadghiri S, Creusat A, Rey S, Delahouliere L, Mathieu E, Vallet M, Brissard A, Brunet C, Derobert I, Lacour M, Zarea A, Martinaud O, Wallon D, Morin A
PubMed: 42961134
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Deciphering the neuroprotective signaling of SGLT2 inhibitors in Alzheimer's disease.

J Alzheimers Dis. 2026 Oct 30;:13872877261502860. Epub 2026 Oct 30
Authors: Kamihara T, Kato R, Morisaki A, Kaneko S, Omura T, Shimizu A
PubMed: 42961128
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Bidirectional transitions between subjective cognitive decline and normal cognition and risk of mild cognitive impairment: A multistate Markov model study in NACC UDS.

J Alzheimers Dis. 2026 Oct 30;:13872877261502867. Epub 2026 Oct 30
Authors: Xiao Y, Zhou Z, Jin M, Wang C, Qian X, Jia F
PubMed: 42961122
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Alzheimer's disease: targeted nanomedicine to mitigate neuroinflammation.

Nanomedicine (Lond). 2026 Oct 30;:1-4. Epub 2026 Oct 30
Authors: Vashist A, Lakshmana MK
PubMed: 42960972
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Periodontal disease, biomarkers of ADRD risk, and cognitive functioning.

J Periodontol. 2026 Oct 30; Epub 2026 Oct 30
Authors: Warren JR, Grodsky E, Muller CL, Manly JJ, Brickman AM, Kim S, Himmelstern J, Demmer RT
PubMed: 42960616
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The Association of Amyloid-β and Tau With Synaptic Dysfunction in Alzheimer's Disease.

Ann Clin Transl Neurol. 2026 Oct 30; Epub 2026 Oct 30
Authors: Roveta F, Mendes AJ, Garibotto V, Boccalini C, Lathuiliere A, Rainero I, Rubino E, Zetterberg H, Ashton NJ, Ribaldi F, Frisoni GB, Alzheimer's Disease Neuroimaging Initiative
PubMed: 42960521
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Plasma and CSF neurofilament light chain measured by Simoa and Lumipulse: an inter-platform comparison across neurological disorders.

Clin Chem Lab Med. 2026 Oct 30; Epub 2026 Oct 30
Authors: Toja A, Quaresima V, Tolassi C, Merati T, Trasciatti C, Signorini SG, Morotti A, Berinato F, Poli L, Stabile L, Girotto I, Bertoni M, Zatti C, Magliozzi A, Martinuzzo C, Pangrazio C, Eshja K, Foresti G, Libri I, Rusi E, Bianchi M, Cristillo V, Volonghi I, Galli A, Rizzardi A, Caratozzolo S, Agosti C, Colao R, Rodolico C, Marcello E, Gardoni F, Di Luca M, Zetterberg H, Ashton NJ, Brugnoni D, Pilotto A, Padovani A
PubMed: 42960454
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Glymphatic Dysfunction as a Multisystem Pathway Linking Systemic Health Conditions to Alzheimer's Disease: Mechanisms, Risk Factors, and Therapeutic Opportunities.

Mol Neurobiol. 2026 Oct 30;63(1)
Authors: Abaresh S, Ivantsova E, Parmar MS
PubMed: 42957838
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Neuroinflammation-Associated Synaptic Dysfunction in Neurodegenerative Diseases: A Dual-Database Parallel Bibliometric Analysis.

J Vis Exp. 2026 Oct 30;(236)
Authors: You L, Ke Z, Zhang B, Yue Lau L, Li B, Hong Z, Aldridge RJ, Whitmore EA, Ji F, Chen Y, Meng S
PubMed: 42965328
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Validation of the Telephone MoCA in iRBD and Parkinson's Disease with Conversion to the Standard MoCA.

Mov Disord Clin Pract. 2026 Oct 30; Epub 2026 Oct 30
Authors: van Hillegondsberg L, Zerenner T, Lawton M, Groenewald K, Razzaque J, Welch J, Ben-Shlomo Y, Hu M
PubMed: 42963896
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Mitochondrial complex IV disruption is a detrimental pathology conferring ssusceptibility to alzheimer's disease.

Mol Psychiatry. 2026 Oct 30; Epub 2026 Oct 30
Authors: Tian J, Jia K, Chen Y, Wang T, Guo L, Swerdlow RH, Du H
PubMed: 42963367
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A background-suppressed CRISPR/Cas13a-HRCA biosensor for ultrasensitive miR-137 detection toward differential screening of Alzheimer's disease.

Talanta. 2026 Oct 30;314:130886. Epub 2026 Oct 30
Authors: Song J, Yue H, Zhang C, Jiao J, Jiao J
PubMed: 42971085
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Phytochemicals in Alzheimer's disease: Mechanistic Insights, Targets, and Future Directions.

Mini Rev Med Chem. 2026 Oct 30; Epub 2026 Oct 30
Authors: Mehra A, Mittal A
PubMed: 42983936
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Reassessing the Amyloid-Neurodegeneration Relationship: Integrating Demographic and Amyloid PET Measures to Estimate AD-Related Glucose Hypometabolism.

Curr Alzheimer Res. 2026 Oct 30; Epub 2026 Oct 30
Authors: Chen C, Bhargava V, Su Y, Reiman E, Chen K
PubMed: 42983922
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Designing Memory into the Medicine Box: A Call for Smarter Adherence Tools in Alzheimer's Care.

Curr Alzheimer Res. 2026 Oct 30; Epub 2026 Oct 30
Authors: Uludag K
PubMed: 42983921
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Targeting the DFG-out conformation of TTBK1 enables the discovery of selective type II neuroprotective inhibitors.

Eur J Med Chem. 2026 Oct 30;321(Pt 3):119468. Epub 2026 Oct 30
Authors: Sanchez-Santos C, Madruga E, Recio J, Diaz-Palacios K, Aledavood E, Lietha D, Gil C, Martinez A
PubMed: 42981879
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Skin biopsy-derived measures of small-fiber loss relate to cognitive impairment in Parkinson's disease.

Parkinsonism Relat Disord. 2026 Oct 30;153:109038. Epub 2026 Oct 30
Authors: Cheng X, Li X, Wu L, Chen S, Gu Q, Li D, Wu S, Zheng J, Ma J, Li X
PubMed: 42981734
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Resveratrol partially restores the expression of the clock genes Per1 and Bmal1 in the suprachiasmatic nucleus of scopolamine-induced Alzheimer's rat model.

Exp Brain Res. 2026 Oct 29;244(12)
Authors: Rezapour R, Jaberi-Asl A, Vasheghani Farahani A, Bahramirad A, Farhadi M, Jameie SB
PubMed: 42961657
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Enhanced Screening for Preclinical Cognitive Vulnerability Using Target-Specific Dwelling Time in the Digital Trail Making Test Part A-A Pilot Study.

Alzheimer Dis Assoc Disord. 2026 Oct 29; Epub 2026 Oct 29
Authors: Tanaka S, Yamagami T
PubMed: 42960914
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Total salvianolic acids protect APP/PS1 mice from Alzheimer's disease by attenuating neuroinflammation through hippocampal lipid regulation.

J Alzheimers Dis. 2026 Oct 29;:13872877261498369. Epub 2026 Oct 29
Authors: Hu P, Zhang M, Wei X, Xiao S, Li B, Liu K, Su G, Han B, Shi X, Wei C, Sun J, Zhang Z, Han Z, Shen L
PubMed: 42957985
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A small-molecule TREM2 agonist for Alzheimer's disease.

Nat Med. 2026 Oct 29; Epub 2026 Oct 29
Authors: O'Leary K
PubMed: 42957774
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Artificial intelligence applications in microbiota-gut-brain axis research: Implications for Alzheimer's disease.

J Alzheimers Dis. 2026 Oct 29;:13872877261500124. Epub 2026 Oct 29
Authors: Lista S, Emanuele E, Cuperlovic-Culf M, Mahdi A, Singh V, López-Ortiz S, Khoramipour K, Merino-País M, Minoretti P, Cisale GY, Heslegrave A, Imbimbo C, Sancesario GM, Bendlin BB, Imbimbo BP, Zetterberg H, Santos-Lozano A
PubMed: 42957639
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Improving the Diagnostic Accuracy of Plasma Alzheimer's Disease Biomarkers With Objective and Subjective Cognitive Screening.

Ann Clin Transl Neurol. 2026 Oct 29; Epub 2026 Oct 29
Authors: Abdolmaleki M, Gaynor LS, Liu D, Hohman TJ, Gifford KA, Zetterberg H, Jefferson AL, Bolton CJ
PubMed: 42957617
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Lack of NRF2 expression alters the dynamics of stress granules promoting the aggregation of ALS disease-associated proteins.

Redox Biol. 2026 Oct 29;98:104462. Epub 2026 Oct 29
Authors: Jiménez-Villegas J, Carnicero-Senabre D, Sicart A, Van Den Bosch L, Cuadrado A, Rojo AI
PubMed: 42976580
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The relation of whole-brain functional connectivity to global amyloid and local tau presence.

Neurobiol Aging. 2026 Oct 29;170:64-75. Epub 2026 Oct 29
Authors: Ziadlou D, Wales R, Chen X, Leung HC, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42981912
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The pathological roles of intrinsically disordered proteins in lysosomal acidification dysfunction in neurodegenerative diseases.

Transl Neurodegener. 2026 Oct 28;15(1)
Authors: Abd-ElRaouf K, Murphy DT, Cheong LY, Zeng J, Lo CH
PubMed: 42958598
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Strain-specific morphology and CNS propagation of template-directed SOD1 aggregation following peripheral nerve inoculation.

Acta Neuropathol Commun. 2026 Oct 28;14(1)
Authors: Keskin I, Sigfridsson I, Skagerberg Ekhtiari E, Marklund M, Mattson S, Brännström T, Marklund SL, Nordström U, Andersen PM
PubMed: 42958460
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Immunometabolic dysregulation of reactive microglia and astrocytes in neurodegenerative diseases: Mechanistic insights and therapeutic implications.

J Neurol Sci. 2026 Oct 28;491:126237. Epub 2026 Oct 28
Authors: Gao C, Shi R, Jiang X, Chai H, He X
PubMed: 42966163
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Multi-Omics Machine Learning Framework Identifies CAPS, NUBPL, and RRBP1 as Hubs Linking Neuroinflammation and Mitophagy in Alzheimer's Disease.

Curr Alzheimer Res. 2026 Oct 28; Epub 2026 Oct 28
Authors: An X, Cao M, Yi Z, Wang Y, Yu W, Ren Z
PubMed: 42983238
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Neuroinflammatory Biomarkers in Neurodegenerative Disease Diagnosis and Progression.

Curr Neurovasc Res. 2026 Oct 28; Epub 2026 Oct 28
Authors: Verma AK, Singh R
PubMed: 42983236
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CSF neurofilament, daily function, and survival correlates of a MOBP risk variant in the Barcelona PSP Registry: an exploratory study.

Parkinsonism Relat Disord. 2026 Oct 27;153:109031. Epub 2026 Oct 27
Authors: Painous C, Fernandez M, Perez-Montesino J, Camara A, Brenlla C, Pérez-Soriano A, de Mena L, Zaro I, Muñoz E, Valldeoriola F, Martí MJ, Garrido A, Sánchez-Gómez A, Maragall L, Tolosa E, Alba-Arbalat S, Camos-Carreras A, Naranjo L, Ruiz-Garcia R, Molina-Porcel L, Llado A, Balasa M, Borrego-Ecija S, Aldecoa I, Tio M, Martin N, Buongiorno M, de Fabregues O, Gonzalez V, Pont-Sunyer C, Delgado T, Lafuente C, Sanchez V, Bargallo N, Casanova-Molla J, Escalante S, Caballol-Pons N, Planas-Ballve A, Avila A, Vila D, Marco C, Jauma S, Bejr-Kasem H, Calopa M, Calvo NM, Mas A, Mas N, Sarto J, Navarro J, Montori-Palacin E, Compta Y
PubMed: 42966009
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Neuroprotective Effects of Natural Products: Innovative Therapeutic Strategies for Preventing the Progression of Neurodegenerative Diseases.

Mini Rev Med Chem. 2026 Oct 27; Epub 2026 Oct 27
Authors: Zou Y, Gong C, Pan C
PubMed: 42983265
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AI-Assisted Cross-Dataset Prioritization of Circulating microRNA Candidates for Alzheimer's Disease.

Curr Alzheimer Res. 2026 Oct 27; Epub 2026 Oct 27
Authors: Wilczyński K
PubMed: 42983255
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Dementia Risk Across Profiles of Subjective Memory Complaints and Slow Gait: Disentangling Cognitive and Motor Contributions.

Curr Alzheimer Res. 2026 Oct 27; Epub 2026 Oct 27
Authors: Du L, Liu T
PubMed: 42983254
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Fecal Microbiota Transplantation in Alzheimer's Disease: A Scoping Review of Human, Registry, and Preclinical Evidence.

Aging Dis. 2026 Oct 26; Epub 2026 Oct 26
Authors: Xu J, Cao Z, Liu Y, Gao A, Kong Y
PubMed: 42970314
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A revised motor unit number estimate detects presymptomatic motor neuron loss in amyotrophic lateral sclerosis.

Clin Neurophysiol. 2026 Oct 26;194:2112448. Epub 2026 Oct 26
Authors: Bilgorai J, Rafferty GF, Carobin A, Scott J, Chen M, Zhou P, Shaw CE, Vanhoestenberghe A, Bashford J
PubMed: 42987653
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A Support Vector Machine Method With Correlation-Based Recursive Feature Elimination for the Early Diagnosis of Alzheimer's Disease.

J Integr Neurosci. 2026 Oct 26;25(10):51378.
Authors: Zhong H, Sheng J, Zhang Q, Gong Z, Zhang R, Sun Z, Zhu X, Cheng Y
PubMed: 42979926
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Rhes as a Potential Modulator of PINK1/Parkin-Dependent Mitophagy in Huntington's Disease.

J Integr Neurosci. 2026 Oct 26;25(10):53852.
Authors: Saim M, Al-Kazzaz H, Ahmad H
PubMed: 42979923
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Directional Sensitivity of Dynamic Cerebral Autoregulation in Alzheimer's Disease and Mild Cognitive Impairment.

Curr Alzheimer Res. 2026 Oct 25; Epub 2026 Oct 25
Authors: Kalidas N, Panerai RB, Beishon L
PubMed: 42983220
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A prospective observational study measuring the stability of plasma pTau181 using the Elecsys Phospho-Tau (181P) plasma immunoassay for early detection of Alzheimer's disease.

Alzheimers Res Ther. 2026 Oct 24;18(1)
Authors: Kurz C, Leonhardt S, Hufnagel A, Wizemann S, Deutelmoser H, Menzel P, Perneczky R
PubMed: 42958309
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Novel sleep scoring method for neurodegenerative diseases: feasibility and reliability in advanced Parkinson disease.

Sleep Med. 2026 Oct 24;149:109334. Epub 2026 Oct 24
Authors: Montini A, Gaig C, Baldelli L, Sala M, Pazzaglia C, Mignani F, Vignatelli L, Zenesini C, Baldin E, Calandra-Buonaura G, Santamaria J, Provini F, Iranzo A
PubMed: 42967379
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Sex-Dependent Effects of Chronic Cannabinoid Treatment on Repetitive Behaviors and Amyloid Burden in APP/PS1 Mice.

Curr Neuropharmacol. 2026 Oct 23; Epub 2026 Oct 23
Authors: Vidal-Palencia L, González-Parra JA, Ramon-Duaso C, Busquets-Garcia A
PubMed: 42983214
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Corrigendum to "Neuropsychological Profiles in Genetic Frontotemporal Dementia: A Meta-Analysis and Systematic Review".

Aging Dis. 2026 Oct 22; Epub 2026 Oct 22
Authors: Poos JM, den Berg EV, Boer L, Meertens-Gunput S, Dopper EG, Seelaar H, Jiskoot LC
PubMed: 42970316
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Rivastigmine and Emerging Nanotechnological Strategies for Targeted Delivery: A Comprehensive Review.

Curr Pharm Des. 2026 Oct 22; Epub 2026 Oct 22
Authors: Babar E, Ur Rehman A, Gul P, Arshad MS, Shah BA, Ahmed N
PubMed: 42973307
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Integrating Network Pharmacology and Experimental Validation to Elucidate the Anti-neuroinflammatory Mechanism of Hemerocallis citrina Baroni Against Alzheimer's Disease.

Comb Chem High Throughput Screen. 2026 Oct 22; Epub 2026 Oct 22
Authors: Xu M, Zhang Y, Jie W, Kang J, Yan T
PubMed: 42973299
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Dopaminergic System: A Potential Therapeutic Target for Alzheimer's and Parkinson's Diseases.

CNS Neurol Disord Drug Targets. 2026 Oct 22; Epub 2026 Oct 22
Authors: Lekkala VD, Lomada D, Reddy MC, Puranik N, Majumder S, Haque MA
PubMed: 42973293
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Artificial Intelligence-integrated Multimodal Neural Biomarkers for Early Risk Stratification in Preclinical Alzheimer's Disease.

Curr Neurovasc Res. 2026 Oct 22; Epub 2026 Oct 22
Authors: Savitha Mol GM, Justin A, Uma Maheswari D, Vengatachalam G
PubMed: 42973291
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High-altitude environments elevate central and peripheral α-synuclein levels and accelerate PD-related pathology.

J Transl Med. 2026 Oct 21;24(1)
Authors: Sun HL, Fan DY, Xie JH, Du Q, Zeng RJ, Hu JN, Liang J, Zhu L, Wang X, Wang HX, Zhao Q, Zhang R, Wang YJ, Zhao HD, Jin WS
PubMed: 42963787
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Natural Bioactive Compound Combinations in Alzheimer's Disease: Gut-brain Axis and Quantitative Interaction Assessment.

Curr Alzheimer Res. 2026 Oct 21; Epub 2026 Oct 21
Authors: He W, Wang Z, Zheng S, Liu F, Zhang Y, Yang L
PubMed: 42973372
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Therapeutic Multifaceted Potential of Melatonin in Neurodegenerative Diseases: From Neuroprotective Mechanisms to Translational Promise.

Curr Med Chem. 2026 Oct 21; Epub 2026 Oct 21
Authors: Roghani M, Taheri M
PubMed: 42973361
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AI-integrated Approaches in Alzheimer's Disease: Linking Molecular Pathways, Biomarkers, and Emerging Therapies.

Curr Drug Targets. 2026 Oct 21; Epub 2026 Oct 21
Authors: Aziz N, Sachan K, Singh A, Srivastava S, Wal P, Gupta R, Sharma KK, Gasmi A
PubMed: 42973348
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Identification of an S-nitrosylation-Related Gene Signature for Alzheimer's Disease via Bulk and Single-Cell Transcriptomic Profiling.

Curr Alzheimer Res. 2026 Oct 20; Epub 2026 Oct 20
Authors: Yi J, Tan J, Zhou L, Gong Q, Hu J
PubMed: 42973345
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Filamin-A links transcriptional disruption to dopaminergic decline in progressive supranuclear palsy.

Brain. 2026 Oct 19; Epub 2026 Oct 19
Authors: Tsujikawa K, Sahashi K, Ito S, Maekawa T, Riku Y, Iwasaki Y, Ogi T, Katsuno M
PubMed: 42974760
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Neuroprotective Effects of Neolamarckia cadamba against β-amyloid-induced Cognitive Dysfunction via Antioxidant and Anti-inflammatory Mechanisms in Rats.

Curr Neurovasc Res. 2026 Oct 19; Epub 2026 Oct 19
Authors: Mishra R, Gupta JK
PubMed: 42973315
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Endothelial BACE1 impairs insulin signaling to drive cerebral small vessel disease and stroke.

Sci Bull (Beijing). 2026 Oct 16; Epub 2026 Oct 16
Authors: Li J, Lin T, Long Z, Lin J, Gao F, Shen Y
PubMed: 42957517
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Exercise, Dynamic Functional Connectivity, and Sex in Alzheimer's Disease: A Hypothesis-Generating Framework for the Sex-Dependent Dynamic Reconstitution Model.

Aging Dis. 2026 Oct 16; Epub 2026 Oct 16
Authors: Gong Z, Xiang Z, Xiang L, Yuan J
PubMed: 42970313
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The Glymphatic System: From Basic Research Advances to Non-Invasive Brain Stimulation Applications-A Narrative Review.

J Integr Neurosci. 2026 Oct 16;25(10):50308.
Authors: Jiang Z, Yue W, Zhang Y, Yu S, Wang H, Luo T
PubMed: 42979929
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Clinical, neuroimaging, and longitudinal progression characteristics of GBA1-associated Parkinson's disease in a Northeast China cohort.

NPJ Parkinsons Dis. 2026 Oct 15;12(1)
Authors: Du X, Wang X, Shen P, Liang Y, Lin X, Chen J, Pan L, Zhang Y
PubMed: 42971995
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Epigenetic Gene-Environment Interactions in Parkinson's Disease.

J Integr Neurosci. 2026 Oct 14;25(10):51645.
Authors: Zhang K, Chen G, Jia J, Zeng X
PubMed: 42979931
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NOD1 and neurodegenerative diseases: Exploring the interplay between innate immune signaling and cognitive decline.

Curr Opin Pharmacol. 2026 Oct 13;91:102681. Epub 2026 Oct 13
Authors: Kalra P, Grewal AK, Singh TG
PubMed: 42966072
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Baseline Physical Frailty Predicts Clinical Outcomes During Lecanemab Therapy in Early Alzheimer's Disease: A Prospective Real-World Cohort Study.

Aging Dis. 2026 Oct 11; Epub 2026 Oct 11
Authors: Shin J, Park YJ, Lee S, Kang J, Lee S, Lee ES, Jung HN, Ryoo I, Chung SJ, Eo JS, Suh SI, Oh K, Koh SB, Kang SH
PubMed: 42970319
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A Lightweight EEG-Based Alzheimer's Disease Detection Framework on an Edge-Computing Platform Toward Future Intelligent Digital Twin Systems.

J Integr Neurosci. 2026 Oct 10;25(10):53849.
Authors: Alqahtani A, Al-Ahmadi S, Soudani A
PubMed: 42979938
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APOE2 attenuates APOE4-associated amyloid pathology and related toxicity in a mouse model of Alzheimer's disease.

Nat Commun. 2026 Oct 8;17(1)
Authors: Chen K, Chen Y, Ren Y, Wang Z, Huang Y, Pan M, Li Z, Casey MC, Qiao W, Shi J, Kong D, Xhafkollari G, Santhakumar H, Wetmore AM, Thompson EA, Wang X, Dickson DW, Holtzman DM, Bu G, Han X, Peng J, Zhao N
PubMed: 42982855
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Anterocollis Following Rotigotine Therapy in Parkinson Disease: Further Evidence for a Dopamine Agonist Class Effect.

Clin Neuropharmacol. 2026 Oct 2; Epub 2026 Oct 2
Authors: Pitton Rissardo J, Fornari Caprara AL
PubMed: 42970457
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A model of brain function to predict tau across Alzheimer's disease and related disorders.

Nat Commun. 2026 Oct 2;17(1)
Authors: Corriveau-Lecavalier N, Zhang G, Botha H, Barnard LR, Wiste HJ, Dicks E, Gogineni VR, Lee J, Sintini I, Senjem ML, Schwarz CG, Cogswell PM, Johnson DR, Gunter JL, Kamykowski MG, Graff-Radford J, Ramanan VK, Fields JA, Machulda MM, Stricker NH, Boeve BF, Lowe VJ, Kantarci K, Knopman DS, Whitwell JL, Josephs KA, Petersen RC, Jack CR Jr, Jones DT, or the Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42967904
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Rethinking neurodegeneration: Placing disease in its physiological context.

PLoS Biol. 2026 Oct;24(10):e3004087. Epub 2026 Oct 30
Authors: Clarke J, Jäkel S
PubMed: 42961880
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ARRDC4 drives Tau pathology via USP14-mediated deubiquitination and acts as a novel therapeutic target in Alzheimer's disease.

Alzheimers Dement. 2026 Oct;22(10)
Authors: Liu J, Xiao BW, Mai X, Wang YC, Fei Y, Wang Y, Hou SX
PubMed: 42957973
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APOE ε4 gene dose drives a canonical and predictable topography of amyloid deposition.

Alzheimers Dement. 2026 Oct;22(10)
Authors: Mendes AJ, Boccalini C, Ribaldi F, Pievani M, Peretti D, Garibotto V, Chincarini A, Frisoni GB, Alzheimer's Disease Neuroimaging Initiative
PubMed: 42957970
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Association of neighborhood deprivation with Alzheimer's disease pathology, brain structure, and cognition by race and ethnicity, sex, and APOE ε4 status.

Alzheimers Dement. 2026 Oct;22(10)
Authors: Aguilar-Dominguez P, Colceriu CM, Holland TM, Lockhart SN, Masdeu JC, Neumann LT, Snyder HM, Baker LD, Bejanin A, Landau SM, Arenaza-Urquijo EM
PubMed: 42967602
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Chronic kidney disease and blood-based biomarkers of Alzheimer's disease: the brain in kidney disease study.

Alzheimers Dement. 2026 Oct;22(10)
Authors: Sheets KM, Curran JM, Mielke MM, Zeng X, Karikari TK, Sutphen CL, Register TC, Murray AM
PubMed: 42967588
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MRI-derived glymphatic-related composite captures brain and cognitive vulnerability associated with cardiovascular risk in older adults.

Alzheimers Dement. 2026 Oct;22(10)
Authors: Wang Z, Lin G, Fang F, Yu J
PubMed: 42967579
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The Emerging Role of α-Synuclein Strains in Parkinson's Disease: From Molecular Pathology to Clinical Phenotypes.

Cureus. 2026 Oct;18(10):e117292. Epub 2026 Oct 1
Authors: Verma A, Tiwari PC, Sharma B, Bihari B, Pal R
PubMed: 42967208
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Polygenic risk scores for LATE-neuropathologic change: Implications for clinical utility.

Alzheimers Dement. 2026 Oct;22(10)
Authors: Pyun JM, Park YH, Shade LM, Fardo DW, Kim S, Nho K, Alzheimer's Disease Neuroimaging Initiative
PubMed: 42963336
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Tau positron emission tomography harmonization using the CenTauR approach: General conversion equations, relevant cut-points, and external validation.

Alzheimers Dement. 2026 Oct;22(10)
Authors: Moscoso Rial A, Leuzy A, Raket LL, Villemagne VL, Klein G, Tonietto M, Olafson E, Smith R, Schwarz CG, Baker S, Saad ZS, Bullich S, Lopresti B, Sanabria Bohorquez S, Domingues Kolinger G, Lutz O, Boada M, Betthauser TJ, Charil A, Collins EC, Collins JA, Gunn RN, Higuchi M, Hostetler E, Hutchison RM, Iaccarino L, Insel PS, Irizarry MC, Jack CR Jr, Jagust WJ, Johnson KA, Johnson SC, Tissot C, Vállez García D, Salvadó G, Stephenson D, Marquié M, Mathotaarachchi S, Mintun MA, Ossenkoppele R, Huang Q, Mao X, Gnörich J, Pappas I, Petersen RC, Chiotis K, Rabinovici GD, Rosa-Neto P, Stephens AW, Whittington A, Carrillo MC, Pontecorvo MJ, Budd Haeberlein S, Dunn B, Kolb HC, Tatton N, Karten Y, Brendel M, O'Bryant S, Xie F, Rowe CC, Hansson O, Doré V, Alzheimer's Disease Neuroimaging Initiative (ADNI), Health and Aging Brain Study (HABS‐HD) Study Team
PubMed: 42963335
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Expert perspectives on the design and communication of endpoints in Alzheimer's disease clinical trials.

Alzheimers Dement. 2026 Oct;22(10)
Authors: Tariot PN, Dickson SP, Dwyer J, Granda C, Hughes L, Karlawish J, Linz N, Nair KV, Paulsen R, Pawson D, Perneczky R, Schindler SE, Scholler E, Taylor J, Tiede B, Vradenburg G
PubMed: 42963333
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Deep learning-based prediction of regional brain Tau PET burden from MRI.

Alzheimers Dement. 2026 Oct;22(10)
Authors: Kim D, Ho BC, van Voorst H, Liu Y, Benzinger TL, Sha S, Mormino E, Henderson VW, Zaharchuk G
PubMed: 42963328
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Creutzfeldt-Jakob Disease as an Ongoing Concern: A Narrative Review.

Cureus. 2026 Oct;18(10):e117478. Epub 2026 Oct 5
Authors: Helm LR, Toftness AR
PubMed: 42985570
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ERBB4 Perturbation Supports a Developmental Cytoskeletal Reactivation Hypothesis in Alzheimer's Disease.

Cureus. 2026 Sep;18(9):e117166. Epub 2026 Sep 29
Authors: Lehrer S
PubMed: 42960311
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Bidirectional Interplay Between Periodontitis and Alzheimer's Disease: Mechanisms, Clinical Management, and Preventive Strategies.

Cureus. 2026 Sep;18(9):e117264. Epub 2026 Sep 30
Authors: Alwithanani NA
PubMed: 42966961
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Disentangling global atrophy burden from local structural patterns reveals clinically relevant heterogeneity in mild cognitive impairment.

BMC Neurosci. 2026 Aug 27;27(1)
Authors: Yang X, Lyu J, Wang J, Quan Y
PubMed: 42963752
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LncRNA FBXL19-AS1 regulates the miR-650/ITGB3 axis to drive pathological progression in Alzheimer's Disease.

Hereditas. 2026 Aug 14;163(1)
Authors: Dou J, Zhu Y, Du Z, Zhang G
PubMed: 42958467
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TDP-43-related cryptic splicing reflects pathological heterogeneity in amyotrophic lateral sclerosis.

Acta Neuropathol Commun. 2026 Aug 8;14(1)
Authors: Ikegami I, Hongo S, Koyama A, Hayakawa-Yano Y, Yano M, Sugai A, Ishihara T, Tada M, Kakita A, Onodera O, Koike YM
PubMed: 42983891
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LRRK2 G2019S variant is associated with transcriptional changes in Parkinson's disease human myeloid cells under proinflammatory environment.

J Neuroinflammation. 2026 Aug 8;23(1)
Authors: Navarro E, Efthymiou AG, Mattei D, Parks M, Riboldi GM, Vialle RA, Udine E, Muller BZ, Humphrey J, Allan A, Argyrou C, de Paiva Lopes K, Münch A, Raymond D, Sachdev R, Shanker VL, Miravite J, Katsnelson V, Leaver K, Frucht S, Bressman SB, Marcora E, Saunders-Pullman R, Goate AM, Raj T
PubMed: 42983839
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MemTrax as a scalable digital triage tool for mild cognitive impairment screening: primary validation in Alzheimer's disease and exploratory analysis in Parkinson's disease.

Alzheimers Res Ther. 2026 Aug 8;18(1)
Authors: Shi X, Kong H, Chen W, Lin L, Yuan K, Su F, Wang Y, Zhang Y, Zhou J, Zhou X, Ashford CB, Li F, Ashford JW, Bergeron MF, Pei Z, Zheng Y, Xian W
PubMed: 42983581
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Lysosomal alkalinization: a convergent mechanism in lysosomal storage disorders and classical neurodegenerative diseases.

Cell Commun Signal. 2026 Aug 8;24(1)
Authors: Dubey AR, Kumar S, Singh R
PubMed: 42983435
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The impact of structural variation on Alzheimer's disease in the Alzheimer's disease sequencing project.

Genome Biol. 2026 Aug 7;27(1)
Authors: Lee S, English AC, Peloso GM, Bis JC, Boerwinkle E, Choi SH, Heard-Costa NL, Lin H, Xia R, Seshadri S, Destefano AL, Fornage M, Sedlazeck FJ
PubMed: 42958586
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Oligodendrocyte Lineage Dysfunction in Alzheimer's Disease: A Bidirectional, Stage-Dependent Account.

Cell Mol Neurobiol. 2026 Aug 7;46(1)
Authors: Ning X, Lan J, Miao J
PubMed: 42980859
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TREM2-LRP1 axis in Alzheimer's disease: pharmacological trade-offs of receptor shedding and functional restoration.

Cell Mol Life Sci. 2026 Aug 7;83(1)
Authors: Kamikubo Y
PubMed: 42980769
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Brain white matter functional alterations in patients with Alzheimer's disease and amnestic mild cognitive impairment.

BMC Med Imaging. 2026 Aug 5;26(1)
Authors: Lin Y, Dai F, Dong D, Jia Y, Zhang J, Chen Y, Ge X, Ding Z, Wang L, Feng Q
PubMed: 42972292
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Regulatory cell death of microglia in common cerebrovascular diseases: mechanism, heterogeneity and therapeutic significance.

J Transl Med. 2026 Aug 5;24(1)
Authors: Cheng J, Zhang C, He Y, Lan X, Zheng Y, Han J, Li J, Zhao Y, Zhang B, Feng S, Cheng F, Wang Q, Li C, Wang X
PubMed: 42983447
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Effects of motion and white matter hyperintensities on reference region based ¹⁸F-SynVesT-1 PET quantification in Alzheimer's disease and healthy volunteers.

EJNMMI Res. 2026 Aug 3;16(1)
Authors: Carron C, Noë S, Vanderlinden G, Koole M, Schramm G, Van Laere K
PubMed: 42957873
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Voxel-based texture similarity networks reveal abnormal brain network topology linked to molecular signatures in amyotrophic lateral sclerosis.

BMC Med. 2026 Aug 3;24(1)
Authors: Zhuang SP, Cai ZW, Huang ZY, Lin LY, Chen S, Zou ZY, Ding H, Qin W, Chen HJ
PubMed: 42972546
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Neuropathological and vascular determinants of cerebral amyloid angiopathy risk: evidence from the NACC cohort.

Alzheimers Res Ther. 2026 Aug 1;18(1)
Authors: Ma L, Wang Y, Goudey B, Jin L, Pan Y
PubMed: 42958434
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Cerebellar Topological Alterations Across the Alzheimer's Disease Continuum.

Psychiatry Clin Psychopharmacol. 2026 Aug;36(4):361-372. Epub 2026 Aug 12
Authors: Zhang C, Liu X, Fan J, Li W, Shi J, Tian M
PubMed: 42964963
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Astrocyte lipid metabolism in brain health and neurodegeneration: from regulatory hub to maladaptive stressor.

Mol Neurodegener. 2026 Aug 1;21(1)
Authors: Wang W, Pan H, Mi Y, Farol J, Yin F
PubMed: 42972384
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Target-area dosimetry-guided photobiomodulation improves pathology and cognitive function in APPswe/PS1dE9 mice.

J Transl Med. 2026 Jul 31;24(1)
Authors: Cao S, Chen Y, Li J, Li Z, Liu D, Zhong L, Dong X, Dai J, Yin H
PubMed: 42958401
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Deciphering the metabolome in Alzheimer's disease.

Mol Neurodegener. 2026 Jul 31;21(1)
Authors: Yang X, Shen Y
PubMed: 42972409
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Impact of heat-induced retrieval methods on silver staining for detecting senile plaques of Alzheimer's disease in human brain tissue sections.

Diagn Pathol. 2026 Jul 29;21(1)
Authors: Zhang ZY, Zhang SS, Wang SD, Cheng K, Yi WH, Li ZW, Zhou JN, Wang XM, Wang CW
PubMed: 42968096
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Effects of the extract of Ginkgo biloba L. on inflammatory response and mitochondrial dynamics in microglia in Alzheimer's disease.

BMC Complement Med Ther. 2026 Jul 28;26(1)
Authors: Liu X, Liu D, Gao Y, Yan S, Liu H, Yang X
PubMed: 42983391
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Socio-clinical profiles and life satisfaction (LS) in individuals with emerging cognitive disorders (MCI or iSCCs) a multicenter cross-sectional study in French university-affiliated memory clinics.

J Public Health Res. 2026 Jul;15(3):22799036261487220. Epub 2026 Sep 18
Authors: Tibi-Levy Y
PubMed: 42973746
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Dysregulation of Expression of Nicotinic Acetylcholine Receptors and Ly6/uPAR Proteins in the Cingulate Gyrus of the Cerebral Cortex of Patients with Alzheimer's Disease.

Acta Naturae. 2026;18(3):48-55.
Authors: Bychkov ML, Ochneva AG, Ushakova VM, Morozova AY, Zorkina YA, Abramova OV, Kostyuk GP, Kirpichnikov MP, Paramonov AS, Lyukmanova EN
PubMed: 42960058
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Retraction: MicroRNA Let-7f-5p Promotes Bone Marrow Mesenchymal Stem Cells Survival by Targeting Caspase-3 in Alzheimer Disease Model.

Front Neurosci. 2026;20:2023227. Epub 2026 Oct 15
Authors: Frontiers Editorial Office
PubMed: 42959676
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Combined administration of buntanetap and dulaglutide counteracts synaptic dysfunction and memory loss in an Alzheimer's disease mouse model.

Alzheimers Dement (N Y). 2026;12(4):e70336. Epub 2026 Oct 28
Authors: Acquarone E, Gutierrez SB, Zhang H, Morin A, Maccecchini M, Arancio O
PubMed: 42959452
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Sex Differences in Domain-Specific Cognitive Trajectories and Dementia Risk: Evidence From the Whitehall II Cohort.

J Aging Res. 2026;2026:1953393. Epub 2026 Oct 28
Authors: Toopchiani S, Sindi S, Janani L, Robinson O
PubMed: 42959399
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Differences in anti-amyloid therapy eligibility assessment based on use of the SWI versus GRE sequence.

Alzheimers Dement (Amst). 2026;18(4):e70524. Epub 2026 Oct 28
Authors: Bermudez C, Pillai JJ, Burkett BJ, McDonald JS, Johnson DR, Wiste HJ, Weigand SD, Jack CR Jr, Vemuri P, Petersen RC, Graff-Radford J, Ramanan VK, Cogswell PM
PubMed: 42959393
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Cognitive transfer and durability of computerised cognitive training in older adults with mild cognitive impairment: a systematic review and meta-analysis of randomised controlled trials.

Front Aging Neurosci. 2026;18:1952783. Epub 2026 Oct 15
Authors: Luo H, Deng L, Long L, Chen W, Yao J, Liu Y
PubMed: 42959097
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Serum neuron-derived extracellular vesicle mitochondrial DNA as a potential biomarker for mild cognitive impairment due to AD.

Front Aging Neurosci. 2026;18:1924123. Epub 2026 Oct 15
Authors: Lin D, Luo Y, Qiu X, Ye P, Chen R, Xu W, Zheng R, Fu X, Fan K, Chen D, Yang B, Chen L, Ou Q, Liu X
PubMed: 42959066
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The "Invisible Killer" of Neurodegeneration: Mitochondrial Dysfunction in Neurodegenerative Disorders, Mechanisms, Emerging Pathways and Therapeutic Strategies.

J Inflamm Res. 2026;19:653025. Epub 2026 Oct 27
Authors: Cao S, Liu T, Cheng X, Tian X, Wei J
PubMed: 42967168
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Mini-Mental State Examination trajectories across dementia subtypes in the Swedish Registry for Cognitive/Dementia Disorders and U.S. National Alzheimer's Coordinating Center.

Alzheimers Dement (Amst). 2026;18(4):e70531. Epub 2026 Oct 30
Authors: Bao X, García Pascual B, Blakstad E, Norgren J, Abzhandadze T, Zhu N, Hoang MT, Chatterjee S, Scolamiero M, Eriksdotter M, Xu H, Ptacek SG
PubMed: 42967021
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Spatial patterns of amyloid clearance after donanemab: A preliminary 12-month real-world amyloid PET study in Japanese patients with early Alzheimer's disease.

Alzheimers Dement (Amst). 2026;18(4):e70539. Epub 2026 Oct 30
Authors: Kujuro Y, Saito M, Maruko M, Qian E, Koh H, Katai H, Hattori H
PubMed: 42966975
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Communication and shared decision-making for anti-amyloid therapy in early Alzheimer's disease: An exploratory qualitative study of real-world audio-recorded clinical encounters.

Alzheimers Dement (N Y). 2026;12(4):e70343. Epub 2026 Oct 30
Authors: Paladino J, Echols H, Thacker A, Gale SA, Ramirez Gomez L, Weizenbaum E, Pu CT, Ritchie C, Shah SJ, Lindenberger E
PubMed: 42966930
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Rapidly Progressive Alzheimer's Disease: Candidate Mechanisms and Diagnostic Challenges.

Clin Interv Aging. 2026;21:638910. Epub 2026 Oct 26
Authors: Cao M, Leng L, Liu P, Fan Z, Peng G
PubMed: 42965095
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Photobiomodulation as a regulator of neuroinflammation: mechanistic insights and therapeutic potential in brain disorders.

Front Neurol. 2026;17:1902491. Epub 2026 Oct 16
Authors: Blivet G, Bertrand C, Brauge D, Delrieu J, Touchon J
PubMed: 42964993
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Agreement and longitudinal repeatability of established brain volumetry pipelines across healthy controls, multiple sclerosis, and Alzheimer's disease.

Front Neurosci. 2026;20:1917471. Epub 2026 Oct 16
Authors: Šišić N, Barakovic M, Edde M, Théberge A, Beaudoin AM, Dumbia M, Lapointe E, Descoteaux M, Magon S, Gobbi S
PubMed: 42964793
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Clinical and Epidemiological Profile of Progressive Supranuclear Palsy in a Colombian Referral Center: A Retrospective Cohort Study.

Neurol Res Int. 2026;2026:9076106. Epub 2026 Oct 29
Authors: Henao-Pérez M, López-Medina DC, Arboleda-Ramírez A, Barroso-Barrera Z, Londoño-Aristizábal JP
PubMed: 42964603
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A newly defined substage of late-stage Alzheimer's disease, the "Dementia Gap": Can sedation to unconsciousness to relieve patients' intolerable suffering be moral?

J Alzheimers Dis Rep. 2026;10:25424823261460085. Epub 2026 Jul 8
Authors: Terman SA
PubMed: 42964420
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Trans-anethole attenuates streptozotocin-induced cognitive dysfunction by modulating oxidative stress and cholinergic activity.

Front Pharmacol. 2026;17:1954658. Epub 2026 Oct 16
Authors: Mole SS, Dwivedi PS, Lobo WL, Shastry CS, Khanal P
PubMed: 42964137
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Cross-sectional associations of Kidney deficiency, Phlegm-stasis, and Heat-toxin syndrome patterns with disease severity in Alzheimer's disease: an exploratory study.

Front Aging Neurosci. 2026;18:1763273. Epub 2026 Oct 16
Authors: Zhang L, An H, Ding M, Yu X, Yan F, Gu C, Li X
PubMed: 42964118
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Early caudate involvement marks a Lewy body spectrum phenotype in parkinsonism: a 5-year longitudinal study.

Front Neurol. 2026;17:1895109. Epub 2026 Oct 16
Authors: Varanese S, Buongarzone MP, Viola S, Ghilardi MF, di Rocco A, Speranza R, Masotino A, Durante C, Bonanni L
PubMed: 42964115
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Case Report: Sporadic Creutzfeldt-Jakob disease initially misdiagnosed as ischemic stroke: a diagnostic challenge and biomarker-based clarification.

Front Cell Neurosci. 2026;20:1938627. Epub 2026 Oct 16
Authors: Hao W, Zhou X, Wang M, Yang W, Cheng T
PubMed: 42964044
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InRegPep: a web server for modeling of parallel beta-sheet fibrillar aggregates of amyloidogenic peptides.

Front Mol Biosci. 2026;13:1908797. Epub 2026 Oct 16
Authors: Puławski W, Niewieczerzał S, Koliński A, Firlik G, Koliński M
PubMed: 42964025
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miR-615-3p targets SESN2 to inhibit neuronal mitophagy in an in vitro Alzheimer's disease model by regulating the AMPK/ULK1 axis.

Front Mol Neurosci. 2026;19:1873619. Epub 2026 Oct 16
Authors: Jing Y, Li D, Chen L, Li S, Yuan X
PubMed: 42964017
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Conductivity-To-Tissue Volume Ratio: Imaging Biomarker for the Alzheimer's Disease Continuum.

Am J Alzheimers Dis Other Demen. 2026;41:15333175261502814. Epub 2026 Nov 2
Authors: Ahn J, Lee MB, Kwon OI, Rhee HY, Jung YJ, Kim Y, Park S, Ryu CW, Lee J, Jahng GH
PubMed: 42969271
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Value of positive RT-QuIC replicate number in sporadic Creutzfeldt-Jakob disease.

BMJ Neurol Open. 2026;8(2):e001863. Epub 2026 Oct 28
Authors: Zavarella M, Hermann P, da Silva Correia S, Eyyuboglu SC, Schmitz M, Filippi M, Zerr I
PubMed: 42968878
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Language Impairment in Alzheimer's Disease: An Updated Narrative Review of Digital Assessment, Social Interventions, and Medical Treatment, 2016-2026.

Clin Interv Aging. 2026;21:633855. Epub 2026 Oct 28
Authors: Klimova B
PubMed: 42968820
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Unveiling the neuroinflammatory potential of aspartame in Alzheimer's disease: A comprehensive network toxicology and experimental validation approach.

PLoS One. 2026;21(11):e0361766. Epub 2026 Nov 3
Authors: Li D, Weng X, Huang Y, Yang D, Yao S, Zheng W, Jiang X, Wei Y, Xu S, Wei C
PubMed: 42976132
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A hybrid CNN-BiLSTM network with additive attention for automated four-stage classification of Alzheimer's disease from brain MRI.

Front Artif Intell. 2026;9:1948601. Epub 2026 Oct 16
Authors: Deenadayalan T, Shantharajah SP, Ramu SP
PubMed: 42974268
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Cancer-Alzheimer inverse comorbidity from epidemiology to protein self-assembly.

Front Endocrinol (Lausanne). 2026;17:1992522. Epub 2026 Oct 19
Authors: Zhang Y, Wang L, Wei J, Shuzan N, Zheng J
PubMed: 42974248
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Immune-endothelial crosstalk at the nexus of neuroinflammation and vascular dysfunction in aging.

Front Immunol. 2026;17:1972284. Epub 2026 Oct 19
Authors: Cui Z, Sun H, Chen Z, Li J
PubMed: 42974162
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The Gut-Brain Homeostatic Continuum in Alzheimer's disease: a systems framework for physiological resilience and disease progression.

Front Neurosci. 2026;20:1963040. Epub 2026 Oct 19
Authors: Jacquier-Sarlin M, Seignobos M, Rauzier L, Schaack B, Laurin D, Buisson A
PubMed: 42974103
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Neural evidence for progressive decline of visual face recognition ability in Alzheimer's disease.

Brain Commun. 2026;8(6):fcag390. Epub 2026 Oct 22
Authors: David J, Quenon L, Ivanoiu A, Koessler L, Colmant L, Salman Y, Huyghe L, Hanseeuw B, Rossion B
PubMed: 42974070
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Utility of extracellular vesicles in the diagnosis of central nervous system diseases.

Front Neurol. 2026;17:1959745. Epub 2026 Oct 19
Authors: Wang M, Yang J, Gao C, Qu S, Mi H, Guo Y, Gui T, Gai Z
PubMed: 42974031
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Identification of Key Genes and Pathways in Parkinson's Disease Through Bioinformatics Analysis.

Bioinform Biol Insights. 2026;20:11779322261489966. Epub 2026 Sep 16
Authors: Lotfi E, Ketabforoush AH, Azeditehrani F, Ahmadirad N, Daneshafrooz N, Golab F
PubMed: 42973917
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Physical exercise: a multi-target strategy for the prevention and treatment of Alzheimer's disease.

Front Aging Neurosci. 2026;18:1876075. Epub 2026 Oct 19
Authors: Tong W
PubMed: 42973868
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Nanomaterial modulation of lysosomal homeostasis in neurodegenerative proteinopathies: from pathological-protein degradation to re-release and seeding.

Front Mol Neurosci. 2026;19:1997252. Epub 2026 Oct 19
Authors: Song M, Bu N, Wei L, Chen J
PubMed: 42973848
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Predictors of 6-month clinical change in primary progressive aphasia following language therapy and transcranial magnetic stimulation.

Brain Commun. 2026;8(6):fcag398. Epub 2026 Oct 19
Authors: Fernández-Romero L, Delgado-Alonso C, Grasso SM, Cabrera-Martín MN, Balugo P, Fraile-Pereda A, Suárez-Coalla P, Barroso Y, Oliver-Mas S, Matias-Guiu J, Olazarán J, Díez-Cirarda M, Matias-Guiu JA
PubMed: 42973818
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Diagnostic reversion in dementia care: A real-world analysis of mild cognitive impairment diagnoses after dementia in a large electronic medical record system.

Alzheimers Dement (Amst). 2026;18(4):e70523. Epub 2026 Nov 1
Authors: Miramontes S, Khan U, Zimmerman S, Ferguson EL, Mills H, Oskotsky B, Phelps E, Oskotsky TT, Capra JA, Glymour MM, Sirota M, Tsoy E
PubMed: 42973575
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Characterizing cognitive concerns in subjective cognitive decline using large language models and electronic health record notes.

Alzheimers Dement (Amst). 2026;18(4):e70525. Epub 2026 Nov 1
Authors: Chen T, Wang J, Varghese S, Tian J, Amariglio RE, Zhou L, Marshall GA, Wang L
PubMed: 42973460
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[Cerebral amyloid angiopathy].

Zh Nevrol Psikhiatr Im S S Korsakova. 2026;126(10):24-31.
Authors: Esin RG, Gorobets EA, Efimova DM, Esin OR
PubMed: 42973250
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[Modifiable risk factors for Alzheimer's disease].

Zh Nevrol Psikhiatr Im S S Korsakova. 2026;126(10):7-15.
Authors: Makhnovich EV, Kovalenko EA, Osinovskaya NA, Shutikova AI, Kovaleva II, Bogolepova AN
PubMed: 42973248
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The efficacy of NMDA receptor antagonists in neuropsychiatric and non-motor symptoms of Parkinson's disease: a systematic review.

Dement Neuropsychol. 2026;20:e20260496. Epub 2026 Nov 2
Authors: Orlino JA, Corrales-Joson ML
PubMed: 42985541
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Decline in mitochondrial health and lysosomal acidification in human neurons during normal aging.

Front Aging Neurosci. 2026;18:1903701. Epub 2026 Oct 20
Authors: Legault EM, Izabal Gamez JP, Drouin-Ouellet J
PubMed: 42985442
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Hesperetin improves cognitive impairment in scopolamine-induced C57BL/6 mice.

Food Nutr Res. 2026;70 Epub 2026 Oct 27
Authors: Moon HR, Yun JM
PubMed: 42984960
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Specific enrichment of somatic single nucleotide variants in Alzheimer-associated tetraploid neurons.

Front Mol Neurosci. 2026;19:1929505. Epub 2026 Oct 21
Authors: López-Sánchez N, Rábano A, Frade JM
PubMed: 42984925
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From developmental divergence to degenerative vulnerability: convergent molecular mechanisms linking autism spectrum disorder and Alzheimer's disease.

Front Mol Neurosci. 2026;19:1963972. Epub 2026 Oct 21
Authors: Griñán-Ferré C, Hussain F, Bellver-Sanchis A, Pérez-Salvador N, Valle Y, Ortuño-Sahagún D, Arias-Carrión O
PubMed: 42984863
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Rapid eye movement sleep behavior disorder as a model of early neurodegeneration: challenges for research and clinical diagnosis.

Front Aging Neurosci. 2026;18:1961735. Epub 2026 Oct 21
Authors: Guerra-Crespo M, Ortega-Robles E, Arias-Carrión O
PubMed: 42984845
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Integrated manufacturing platform for cortical organoids reveals early phosphatase and prefoldin dysregulation in MAPT V337M neurons.

NPJ Dement. 2026;2(1):100. Epub 2026 Nov 3
Authors: Bertucci T, Bowles KR, Lotz S, Bheda S, Qi L, Farjood F, Whitton K, Goderie SK, Borden S, Rossi A, Hamann C, Tubbesing K, Rogalski J, Murphy D, Pedicone C, Oja LM, Lane K, Lotz R, Lotz H, Huber J, Chowdhury R, Joy S, Miller M, Butler DC, Arduini BL, Kiehl TR, Murray HF, Sandhof CA, Silva MC, Haggarty SJ, Dony L, Theis FJ, Treutlein B, Karch CM, Geschwind DH, Goate AM, Stern J, Temple S
PubMed: 42984670
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Restoring Parkin function: an AAV gene therapy approach for early-onset Parkinson's disease.

Front Mol Neurosci. 2026;19:1939065. Epub 2026 Oct 21
Authors: Basu S, Demarest TG, Gattone NJ, Gilsrud AJ, Wicks B, Khatiwada A, Nayal M, Gentzel R, Cohen DM, Kostuk EW, Narendra DP, Gonzalez-Alegre P, Biferi MG, Ramsburg EA
PubMed: 42984644
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[Alzheimer's Disease: When the evidence does not justify reimbursement for a drug].

Epidemiol Prev. 2026;50(4-5):361-364.
Authors: Traversa G
PubMed: 42984363
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AmyloDeep: protein language model-based ensemble model for predicting amyloid propensity from the amino acid sequence.

Bioinform Adv. 2026;6(1):vbag296. Epub 2026 Oct 6
Authors: Davtyan A, Khachatryan A, Petrosyan R
PubMed: 42979591
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Emerging and Repurposed Immune System Modulators for Alzheimer's Disease.

Drug Des Devel Ther. 2026;20:559284. Epub 2026 Oct 30
Authors: Decourt B, Azarfar K, Reyna EM, Kennedy JM, Sabbagh MN
PubMed: 42979167
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Efficacy of ORM-12741 on agitation/aggression symptoms in participants with Alzheimer's disease.

Alzheimers Dement (N Y). 2026;12(4):e70332. Epub 2026 Nov 2
Authors: Rinne JO, Cummings JL, Breznoscakova D, Hakulinen P, Hänninen J, Goetghebeur P, Miller DS, Rouru J
PubMed: 42979037
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Item-level verbal fluency psycholinguistic metrics predict preclinical Alzheimer's disease.

Alzheimers Dement (Amst). 2026;18(4):e70533. Epub 2026 Nov 2
Authors: Sugarman MA, Stabile M, Clark DG, Nietert PJ, Rodriguez-Porcel F, Bushnell J, Benitez A
PubMed: 42979035
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Remote versus in-person cognitive testing: the impact of visit modality on longitudinal cognitive outcomes in older adults.

Alzheimers Dement (Amst). 2026;18(4):e70530. Epub 2026 Nov 2
Authors: Leng Y, He Y, Mechanic-Hamilton D, Clark LR, Sachs BC, Lamar M, Beattie ZT, Saykin AJ, Barnes LL, Duff K, Capuano AW, Das S
PubMed: 42979031
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Decomposed arterial stiffness and NfL-cognition association in older adults: The IGNITE study.

Alzheimers Dement (Amst). 2026;18(4):e70507. Epub 2026 Nov 2
Authors: Norling AM, Collins AM, Sewell KR, Wan L, Grove G, Huang H, Hughes TM, Gepner AD, Sekikawa A, Oberlin LE, Karikari TK, Morris JK, Jakicic JM, Rogers RJ, Forman DE, McAuley E, Kramer AF, Hillman CH, Vidoni ED, Billinger SA, Burns JM, Marsland AL, Kang C, Erickson KI
PubMed: 42979025
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Multi-platform comparison of plasma phosphorylated tau assays: analytical and workflow factors drive clinical implementation decisions.

Alzheimers Dement (Amst). 2026;18(4):e70465. Epub 2026 Nov 2
Authors: Sandoval-Boczkowska O, Best JR, Smith RJ, Burns L, Helbling C, Hsiung GR, Pettersen JA, Lee PE, Henri-Bhargava A, Nygaard HB, DeMarco ML
PubMed: 42979019
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Cognitive and brain reserve in bilingual speakers with clinical AD variants.

Alzheimers Dement (Amst). 2026;18(4):e70506. Epub 2026 Nov 2
Authors: Biondo N, Suntay JM, Mandelli ML, Sandhu M, Estaban JS, Pillai J, Mamuyac E, Reyes RJ, Guevarra A, Henry ML, Dronkers NF, Gorno-Tempini ML, Grasso SM, de Leon J
PubMed: 42978977
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Neuropsychiatric symptoms across the revised Alzheimer's disease clinical staging framework: A review of current evidence and implications.

Alzheimers Dement (Amst). 2026;18(4):e70510. Epub 2026 Nov 2
Authors: Sankhe K, Vellone D, Guan DX, Creese B, Ismail Z, Kumar S, Lanctôt KL, Mortby ME, de Oliveira FF, Sinclair L, Gatchel J, Munro CE
PubMed: 42978812
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Integrated computational screening and biochemical validation identify natural small molecules targeting Aβ aggregation and dissociation.

J Pharm Pharm Sci. 2026;29:17216. Epub 2026 Oct 20
Authors: Lee H, Kumar V, Shin SJ, Nam Y, Jang S, Kim HS, Lee M, Song GY, Lim EK, Chae HJ, Moon M
PubMed: 42978683
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