Alzforum - Papers of the Week: 3-9 Apr 2026

The impact of seasons on cognitive function, neuropsychiatric symptoms, and activities of daily living in patients with Alzheimer's disease.

Ann Med. 2026 Dec;58(1):2654104. Epub 2026 Apr 3
Authors: Kong L, Xie D, Luo D, Guan R, Han C
PubMed: 41931120
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tDCS improves early Alzheimer's disease by synaptic vesicle fusion and release.

Mil Med Res. 2026 Dec;13(1):100003. Epub 2026 Mar 25
Authors: Zhuang YY, Yan JM, Wu TC, Xu WS, Wu B, Xie X, Wang WJ, Lin HW, Jian JW, Wang JZ, Jiang T, Chen LM, Qiu YX, Hu ZY, Zhou YH, Yang T, Yang MG, Zhu JF, Tao J, Chen LD, Li WG, Yan K, Liu WL
PubMed: 41953054
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Salvianolic acid a inhibits neuroinflammation and ameliorates Alzheimer's disease pathology via the p38 MAPK/NF-κB pathway based on network pharmacology and experimental validation.

Int Immunopharmacol. 2026 Jun 1;178:116594. Epub 2026 Apr 1
Authors: Xiao S, Han Y, Yan J, Wu L, Lin H, Yuan C, Song C, Ye J
PubMed: 41930874
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Role of aging‑related cytokines in neurodegenerative disease (Review).

Int J Mol Med. 2026 Jun;57(6) Epub 2026 Apr 3
Authors: Dai X, Rao X, Wang Y, Zhao W
PubMed: 41930561
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Effect of edaravone on synaptic damage in Alzheimer's disease via Rho/ROCK signaling.

Pak J Pharm Sci. 2026 Jun;39(6):1625-1630.
Authors: Li Y, Lai Q, Li Q, Fan Y
PubMed: 41934300
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Association of Circulating Vitamin D in Midlife With Increased Tau-PET Burden in Dementia-Free Adults.

Neurol Open Access. 2026 Jun;2(2) Epub 2026 Apr 1
Authors: Mulligan MD, Scott MR, Yang Q, Wang R, Ghosh S, Johnson KA, Beiser AS, Seshadri S, McGrath ER
PubMed: 41938573
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Post-Mortem Delay Induces Distinct Transcriptional and Morphological Changes in Microglia With Age-Specific Patterns.

Glia. 2026 Jun;74(6):e70144.
Authors: Kozlov S, Schmidt E, Theis H, De Domenico E, Beyer MD, Halle A
PubMed: 41943591
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Plant-Based Dietary Patterns and Risk of Alzheimer Disease and Related Dementias in the Multiethnic Cohort Study.

Neurology. 2026 May 12;106(9):e214916. Epub 2026 Apr 8
Authors: Park SY, Setiawan VW, Crimmins EM, White LR, Haiman CA, Wilkens LR, Le Marchand L, Lim U
PubMed: 41950435
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Neurovascular Unit Dysfunction and Cerebral Small Vessel Disease in Parkinson Disease: A Systematic Review and a Meta Analysis.

Neurology. 2026 May 12;106(9):e214873. Epub 2026 Apr 9
Authors: Del Papa DF, Herman J, Kunju AT, Najafi T, O'Boyle R, Salama A, Hneiny L, Samarakoon T, Peabody T, Marmol S, Feldman M, Haq IU
PubMed: 41955557
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Loneliness as an Interface Between Alzheimer's Disease and Suicidal Behaviour: A Systematic Review, Meta-Analysis and Meta-Analytic Factor Analysis.

Psychogeriatrics. 2026 May;26(3):e70165.
Authors: Rodrigues JF, Rodrigues LP, Teshima T, Yang S, Wu Y, Hu X, Abarca GI, da Cruz KC, Rodriguez MF, Rubatino FV, Yamakawa M, de Godoy MF, Filho GM
PubMed: 41944421
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Long-Term Exposure to Ambient Air Pollution and Incident Amyotrophic Lateral Sclerosis: A Prospective Cohort Analysis of the UK Biobank.

Neurology. 2026 Apr 28;106(8):e214858. Epub 2026 Apr 3
Authors: Chalitsios CV, Rudolf O, Gao J, Turner MR, Thompson AG
PubMed: 41931746
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Extent of Tau and Its Cognitive Implications in Patients With Cerebral Amyloid Angiopathy Without Cognitive Impairment.

Neurology. 2026 Apr 28;106(8):e214859. Epub 2026 Apr 7
Authors: Gokcal E, Becker JA, Horn MJ, Das AS, Viswanathan A, Rosand J, Polimeni JR, Sperling RA, Johnson KA, Greenberg SM, Gurol ME
PubMed: 41945879
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Cognitive Reserve in Genetic Alzheimer Disease: Why the Brain's "Buffer" Matters More Than We Thought.

Neurology. 2026 Apr 28;106(8):e214887. Epub 2026 Apr 8
Authors: Jung J
PubMed: 41950469
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Effect of Cognitive Reserve on Age at Symptom Onset and Cognitive Decline in Individuals With Dominantly Inherited Alzheimer Disease.

Neurology. 2026 Apr 28;106(8):e214804. Epub 2026 Apr 8
Authors: Llibre-Guerra JJ, Lu R, Clarens MF, Liu I, Renton A, Ryan NS, Goate AM, Aguillón D, Allegri RF, Benzinger TL, Berman S, Chhatwal JP, Chrem Mendez P, Vigo G, Cruchaga C, Day GS, Farlow MR, Fox NC, Gordon BA, Hassenstab J, Huey ED, Ibanez L, Ikeuchi T, Jucker M, Lee JH, Levey AI, Levin J, Niimi Y, Perrin RJ, Rosa-Neto P, Sánchez-Valle R, Schofield PR, Wang G, Li Y, Xiong C, Morris JC, Karch C, Daniels AJ, McDade E, Bateman RJ
PubMed: 41950468
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Potential crosstalk between Parkinson's disease and glucose metabolism.

J Biomed Res. 2026 Apr 25;:1-10. Epub 2026 Apr 25
Authors: Li Y, He X, Lan J, Bai L, Huang T, Zhang X
PubMed: 41947366
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Maternal Choline Supplementation in a Mouse Model of Down Syndrome and Alzheimer's Disease Generates Unique Expression Profile Mosaics Within Three Hippocampal Excitatory Neuronal Populations.

FASEB J. 2026 Apr 15;40(7):e71625.
Authors: Alldred MJ, Ibrahim KW, Pidikiti H, Lee SH, Heguy A, Chiosis G, Mufson EJ, Stutzmann GE, Ginsberg SD
PubMed: 41930605
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Timing the decline: Cellular circadian rhythms and Alzheimer's disease.

Proc Natl Acad Sci U S A. 2026 Apr 14;123(15):e2604049123. Epub 2026 Apr 6
Authors: Colwell CS
PubMed: 41941651
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Benzimidazole as a Versatile Scaffold for Developing Neurotherapeutics Against Neurodegenerative Diseases.

ChemMedChem. 2026 Apr 14;21(7):e202500869.
Authors: Barnwal N, Dubey S, Tiwari P
PubMed: 41945799
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Coordination of Anle138b to Silver Results in Selective Reduction of a C-Terminal Truncated α-Synuclein Protein and Increased Aggregate Size.

ChemMedChem. 2026 Apr 14;21(7):e202500890.
Authors: Rue KL, Herrera S, Shi ZC, Chakraborty I, Tachiki J, Ballesteros J, Andersen JK, Lithgow GJ, Al Isawi WA, Mezei G, Schmidt M, Raptis RG
PubMed: 41957541
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Restoration of gamma center frequency via personalized entrainment marks cognitive preservation in early Alzheimer's disease.

Geroscience. 2026 Apr 10; Epub 2026 Apr 10
Authors: Park Y, Chae H, Yoon E, Kim Y, Han JW, Woo SJ, Yoo S, Kim KW
PubMed: 41957314
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Elimination of senescent cells fails to attenuate disease progression in an ALS mouse model.

Neurol Sci. 2026 Apr 10;47(5)
Authors: Fang L, Bai Z, Yang D, Sun B, Zhao X, Deng J
PubMed: 41957276
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The genetic associations of DNAJC family members with Parkinson's disease: comprehensive evidence from burden analysis and Mendelian randomization.

Hum Genet. 2026 Apr 9;145(1)
Authors: Yang D, Xu J, Zhu Y, Lu Y, Yao R, Ye Z, Yu B, Chen J, Zhang T, Liu B, Huang S, Chen G
PubMed: 41951985
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Intranasal co-delivery of riluzole and berberine via chitosan-coated PLGA nanoparticles for synergistic neuroprotection in Alzheimer's disease: formulation, characterization, and pharmacokinetics analysis.

Naunyn Schmiedebergs Arch Pharmacol. 2026 Apr 9; Epub 2026 Apr 9
Authors: Komy MH, Aldosari BN, Zaki RM, Bafail R, Yusif RM, Abdelgawad MA, Elmowafy M, Abuhelwa AY, Eid HM
PubMed: 41951843
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Single nucleotide polymorphisms affecting galantamine binding to acetylcholinesterase in Alzheimer's disease: a structural bioinformatics study.

J Comput Aided Mol Des. 2026 Apr 9;40(1)
Authors: Islam N, Akçesme B
PubMed: 41951832
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ADT-OH promotes mitophagy and suppresses the cytosolic mtDNA-cGAS-STING inflammatory cascade in microglia.

Acta Pharmacol Sin. 2026 Apr 9; Epub 2026 Apr 9
Authors: Hou XO, Wang M, Deng R, Lu YF, Zhang JR, Ren L, Chen J, Liu CF, Yang YP, Hu LF
PubMed: 41951774
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Contributions of vascular ageing to late-onset Alzheimer's disease.

Exp Physiol. 2026 Apr 9; Epub 2026 Apr 9
Authors: Ferguson SJ, Choi YD, Walker AE
PubMed: 41957539
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Prodromal changes in cortical neuron physiology before amyloid pathology in a mild model of Alzheimer's disease.

Sci Rep. 2026 Apr 9; Epub 2026 Apr 9
Authors: Milicevic KD, Abreu AC, Chandran G, Zhu YM, Hu X, Ivanova VO, Jami M, Simon B, Fernández I, Yan R, Antic SD
PubMed: 41957486
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Trajectories of plasma and CSF MTBR-tau243 and phosphorylated-tau species across the Alzheimer's disease continuum.

Nat Commun. 2026 Apr 9;17(1)
Authors: Collij LE, Salvadó G, Horie K, Barthélemy NR, Betthauser TJ, Strandberg O, Smith R, Palmqvist S, Schindler SE, Ossenkoppele R, Janelidze S, Mattsson-Carlgren N, Bateman RJ, Hansson O
PubMed: 41957377
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Astrocyte-related proteins mediate the association of YWHAG with Alzheimer's pathology and enhance its diagnostic value.

Transl Psychiatry. 2026 Apr 9; Epub 2026 Apr 9
Authors: Zhang Z, Huang P, Yang Y, Wu H, Yao X, Wang Y, Yi H, Ning K, Chen Y, Wu Y, Chen Z, Shen P, Hong D, Huang X, Zou WQ
PubMed: 41957344
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Imaging-genetics-based dementia risk prediction using deep survival neural networks in the Rotterdam Study.

Sci Rep. 2026 Apr 9; Epub 2026 Apr 9
Authors: Yu J, Rosbergen MT, Wolters FJ, Bron EE, Vernooij MW, Ikram MA, Roshchupkin GV
PubMed: 41957153
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Dissecting genetic variant contributions to neurodegenerative disorders through targeted gene sequencing in a Sicilian population.

Sci Rep. 2026 Apr 9; Epub 2026 Apr 9
Authors: Treccarichi S, Papa C, Vinci M, Cosentino FI, Scalia G, Mostile G, Zappia M, Nicoletti A, Pennisi M, Musumeci A, Chiavetta V, Di Stefano V, Piccoli T, Blandino V, Tripodi M, Lanuzza B, Morreale M, Cupidi C, Ferri R, Lanza G, Cali F
PubMed: 41957096
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Cerebellar oligodendrocytic α-synuclein pathology and dentate nucleus neuronal hypertrophy in Parkinson's disease.

Sci Rep. 2026 Apr 9; Epub 2026 Apr 9
Authors: Iacono D, Peng H, Bouffard JP, Kurlan R
PubMed: 41957057
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Stages of objective memory impairment are associated with accelerated brain aging.

Sci Rep. 2026 Apr 9;16(1)
Authors: Flo BK, Skouras S, Matziorinis AM, Bashevkin T, Gaser C, Koelsch S
PubMed: 41957047
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Lipid droplets in neurodegenerative diseases: pathological drivers and therapeutic vulnerabilities.

Cell Death Discov. 2026 Apr 9; Epub 2026 Apr 9
Authors: Papapanagiotou O, Cotton K, Edwards C, Michod D, Crompton L, Craig T, Niklison-Chirou MV
PubMed: 41956992
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Nanoplastics and Neurodegeneration: A Roadmap From Mechanism to Causation.

Adv Sci (Weinh). 2026 Apr 9;:e75151. Epub 2026 Apr 9
Authors: Li Y, Wang Y, Liang X, Xu M, Leong DT, Ke PC
PubMed: 41955522
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A Single-Vesicle Electroanalytical Approach Uncovers Deficits of Vesicular Acetylcholine Content in Alzheimer's Disease.

J Am Chem Soc. 2026 Apr 9; Epub 2026 Apr 9
Authors: Jiang Y, Liu L, Xiong M, Liu W, Wang H, Liu Y, Cao L, Zhou J, Li C, Yuan C, Mao L, Li X
PubMed: 41955089
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Dysregulation of astrocytic DNAJC6 contributes to sporadic Parkinson's disease pathogenesis.

J Clin Invest. 2026 Apr 9; Epub 2026 Apr 9
Authors: Darsono WH, Hwang Y, Valencia E, Gunawan LT, Hyeon SJ, Ryu H, Stein TD, Chang MY, Wulansari N, Lee SH
PubMed: 41955024
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Roles of Lcn2 and neuroinflammation in a scopolamine-induced cognitive impairment animal model: implication of the NLRP3 inflammasome pathway.

Genes Genomics. 2026 Apr 9; Epub 2026 Apr 9
Authors: Lee MY, Campomayor NB, Apare B, Park RE, Kim D, Kim HJ, Kim M
PubMed: 41954880
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Nano-magnolol enhances the modulatory effects of magnolol on cognitive performance and BACE1-related biochemical changes in an STZ-induced rat model of Alzheimer's disease.

Discov Nano. 2026 Apr 9;21(1)
Authors: Youssef B, Ibrahim EA, Moselhy SS, ElShebiney S, ELabd WK
PubMed: 41954680
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Parkinson's disease dementia and hearing impairment, are they related? A UK biobank pilot analysis.

Exp Brain Res. 2026 Apr 9;244(5)
Authors: Readman MR, Giebel C, Cannon J, Fairman I, Plack CJ
PubMed: 41954638
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CVN-424: An Advanced GPR6 Inverse Agonist in Phase III Clinical Trials for Parkinson's Disease.

J Med Chem. 2026 Apr 9;69(7):7507-7511.
Authors: Tian X, Ali S, Allen JA, Zhou J
PubMed: 41952522
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Structural hormesis in protein aggregation: A minimal mechanistic model.

J R Soc Interface. 2026 Apr 8;23(237)
Authors: Mallela A, Schnell S
PubMed: 41946517
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Rapid elongation drives the exceptionally fast aggregation of the most common localized human amyloid medin.

Commun Chem. 2026 Apr 8; Epub 2026 Apr 8
Authors: Roy Chowdhury V, Horne RI, Cali MP, Toprakcioglu Z, Linse S, Vendruscolo M
PubMed: 41951867
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Population-scale repeat expansions elucidate disease risk and brain atrophy.

Nature. 2026 Apr 8; Epub 2026 Apr 8
Authors: Pounraja VK, Sul JH, Herman J, O'Keeffe S, Rajagopal V, Bai X, Kessler MD, Parikshak N, Landheer K, Zhang X, Yu S, Zhang L, LeBlanc MG, Rico-Varela J, Grau F, Wolf S, Sundaramoorthy S, Sepehrband F, Stahl EA, Huo Y, Ahmed M, Croll S, GHS-RGC DiscovEHR Collaboration, Mayo-RGC Project Generation, Penn Medicine BioBank, Salerno W, Overton JD, Marchini J, Reid J, Lotta LA, Baras A, Regeneron Genetics Center, Abecasis GR, Coppola G, Gelfman S
PubMed: 41951733
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Distinct finger-tapping feature in progressive supranuclear palsy correlates with motor function and brain atrophy.

NPJ Parkinsons Dis. 2026 Apr 8; Epub 2026 Apr 8
Authors: Chen Z, Xu W, Duan R, Tian M, Yang Q, Yin Y, Tang X, Wen T, Guo D, Liu Y
PubMed: 41951686
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Braking Parkinson's progression: the hypothetical druggable role of striatal parvalbumin interneurons.

NPJ Parkinsons Dis. 2026 Apr 8; Epub 2026 Apr 8
Authors: He Q, Wang X, Zhang X, Shu Y
PubMed: 41951621
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The social dimension of apathy: evidence for a distinct domain from 11,243 individuals across health and neurocognitive disorders.

Transl Psychiatry. 2026 Apr 8; Epub 2026 Apr 8
Authors: Zhao S, Ye R, Tang QY, Attaallah B, Toniolo S, Saleh Y, Rouse MA, Garrard P, Broulidakis MJ, Thompson S, Manohar SG, Irani SR, Ang YS, Lockwood P, Apps MA, Hu P, Wang K, Rowe JB, Le Heron C, Husain M
PubMed: 41951598
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Whole-genome sequencing reveals an East Asian-specific rare variant of INPP5J associated with Alzheimer's disease.

Transl Psychiatry. 2026 Apr 8; Epub 2026 Apr 8
Authors: Kimura T, Yamakawa A, Mitsumori R, Niida S, Ozaki K, Shigemizu D
PubMed: 41951582
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Application of digital tools in Alzheimer's disease.

J Formos Med Assoc. 2026 Apr 8; Epub 2026 Apr 8
Authors: Tang L, Mo Y, Bao D, Chen C
PubMed: 41951483
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Susceptibility-weighted imaging in patients with Corticobasal Syndrome or Progressive Supranuclear Palsy: distribution of iron deposits reflects clinical symptoms in 4-R tauopathies.

AJNR Am J Neuroradiol. 2026 Apr 8; Epub 2026 Apr 8
Authors: Migaleddu G, Del Prete E, Donatelli G, Frosini D, Ceravolo R, Cosottini M
PubMed: 41951427
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A human iPSC model of tauopathies engineered for 4R tau isoform expression endogenously develops late-stage neuronal tau pathology.

Sci Transl Med. 2026 Apr 8;18(844):eadu9845. Epub 2026 Apr 8
Authors: Dannert A, Schulz N, Klimmt J, Knez L, Groschup B, Gonçalves CC, Carraro C, Schifferer M, Brendel M, Paquet D
PubMed: 41950304
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Determination of α-Synuclein Protein Interactions by μMap Photoproximity Labeling.

J Am Chem Soc. 2026 Apr 8; Epub 2026 Apr 8
Authors: Lougee MG, Park GS, Kim HJ, Fowler JZ, Lin Z, Fazelinia H, Yanagawa E, Pagar VV, Chio TI, Spruce L, Lee VM, Garcia BA, Lakadamyali M, Petersson EJ
PubMed: 41950200
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Parkinson's disease: pathogenesis and therapeutic strategies.

Mol Biomed. 2026 Apr 8;7(1)
Authors: Zhang S, Wang T, Peng Y, Wang Q, Zhang Z, Chu S, Huang H, Chen N
PubMed: 41949708
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The interventional effect of acupuncture on overall cognitive function in Alzheimer's disease spectrum disorders: A meta-analysis.

J Alzheimers Dis. 2026 Apr 8;:13872877261438495. Epub 2026 Apr 8
Authors: Chen Y, Zhao S, Yang F, Wang Y, Han Z, Han F, Wang Z, Chen Z, Sun K, Liang P, Li K
PubMed: 41949488
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Association of Gastrointestinal Symptoms With Severity and Progression of Cognitive Impairment in Parkinson's Disease: A Systematic Review and Meta-Analysis.

J Gastroenterol Hepatol. 2026 Apr 8; Epub 2026 Apr 8
Authors: Ho K, Khan J, Cheloff AZ, Malhotra A, Shaukat A
PubMed: 41948786
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Response to "Comment on 'Alzheimer's disease diagnosis: An update and review of biomarkers, positron emission tomography, and emerging therapies.".

J Formos Med Assoc. 2026 Apr 8; Epub 2026 Apr 8
Authors: Chen PH, Hsu JL
PubMed: 41956888
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Tau seeds induce neurofibrillary tangle formation across brain regions via individual-specific connectivity.

Neuron. 2026 Apr 8; Epub 2026 Apr 8
Authors: Weber AJ, Ng B, Greathouse KM, Bennett DA, Tasaki S, Gaiteri C, Herskowitz JH
PubMed: 41956094
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Moving toward a more rigorous science of recruitment in clinical research. Commentary on "Evaluating evidence-based recruitment strategies for Alzheimer's disease and related dementias clinical trial research: a literature review".

J Prev Alzheimers Dis. 2026 Apr 8;13(5):100561. Epub 2026 Apr 8
Authors: Perales-Puchalt J, Vidoni ED
PubMed: 41955650
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Faecal microbiota transplant for Parkinson's disease.

Brain. 2026 Apr 8; Epub 2026 Apr 8
Authors: Santens P, Bruggeman A, Laukens D, Vandenbroucke RE
PubMed: 41955275
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RNA polymerase II drives FUS and EWSR1 exclusion from damaged chromatin.

Cell Rep. 2026 Apr 8;45(4):117236. Epub 2026 Apr 8
Authors: Varhoshkova S, Sang CC, Antonova L, Uzunova S, Kirova D, Aleksandrov R, Kanemaki MT, Lee HO, Stoynov S
PubMed: 41955098
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Assessing racial disparities in dementia-related vulnerabilities: a machine learning analysis of social, environmental, and climate factors.

Ethn Health. 2026 Apr 8;:1-17. Epub 2026 Apr 8
Authors: Amiri S, Bensken WP, Buchwald D
PubMed: 41952418
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Biochemical and Immunohistochemical Associations of TDP-43 and Cryptic RNA With Hippocampal and Amygdala Volumetrics in Alzheimer's Disease.

Ann Neurol. 2026 Apr 8; Epub 2026 Apr 8
Authors: Youssef H, Gatto RG, Ghayal NB, Estades Ayuso V, Jansen-West KR, Dunmore JA, Song Y, Yue M, Cook CN, DeTure M, Rawlinson BD, Castanedes-Casey M, Jack CR Jr, Petersen RC, Dickson DW, Petrucelli L, Whitwell JL, Prudencio M, Josephs KA
PubMed: 41952326
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Iron deficiency and dementia risk: evidence from the Swedish population-based cohort study AMORIS.

BMC Med. 2026 Apr 8;24(1)
Authors: Ding M, Wennberg A, Ek S, Hammar N, Schmidt-Mende K, Modig K
PubMed: 41952150
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Epidemiologic and clinical features of Alzheimer's disease: a hospital study based on the memory clinic in Abidjan, Côte D'ivoire, Sub-Saharan Africa.

BMC Neurol. 2026 Apr 7; Epub 2026 Apr 7
Authors: Kouassi KL, Ehoulan FR, Beuseize AM, Broh NY, Essoin-De Souza AN, Yeo NS, Abbé AS, Doumbia-Ouattara M
PubMed: 41942948
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Opposing patterns of blood-brain barrier permeability and Alzheimer's disease biomarkers across APOE genotype.

Neurol Sci. 2026 Apr 7;47(5)
Authors: Bernocchi F, Bonomi CG, Poli M, Di Donna MG, Terrinoni A, Motta C, Martorana A
PubMed: 41942760
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Tau accumulation increases the susceptibility to effective seizures of electroconvulsive therapy.

Transl Psychiatry. 2026 Apr 7; Epub 2026 Apr 7
Authors: Ohya T, Arakawa R, Sakayori T, Nogami T, Uchiyama S, Tateno A
PubMed: 41942439
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The potential of low-field MRI for global dementia care.

Nat Rev Neurol. 2026 Apr 7; Epub 2026 Apr 7
Authors: Evans TE, Harper J, Salehi A, Webb AG, Cole JH, Correa A, Adams HH, Cash DM, Jones DK
PubMed: 41946975
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Deep sleep slow wave-spindle coupling is selectively linked to plasma amyloid-β levels in older adults in clinical trials.

Sci Rep. 2026 Apr 7;16(1)
Authors: Wunderlin M, Wicki K, Teunissen CE, Züst MA
PubMed: 41946900
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Convergent coexpression reveals shared biological mechanisms underlying common and rare variant risk in six neuropsychiatric disorders.

Mol Psychiatry. 2026 Apr 7; Epub 2026 Apr 7
Authors: Abe H, Liao C, Han L, Morley T, Talkowski ME, Brennand KJ, Ruderfer DM
PubMed: 41946833
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Repurposing FDA-approved drugs as multi-target neuroprotective agents for Alzheimer's disease via computational screening and experimental validation.

Sci Rep. 2026 Apr 7;16(1)
Authors: Phemphunananchai K, Waiwut P, Phetcharaburanin J, Poonsawas P, Boonyarat C
PubMed: 41946775
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Growth hormone-releasing hormone attenuates amyloid deposition and neuroinflammation in Alzheimer's disease models.

Cell Death Dis. 2026 Apr 7; Epub 2026 Apr 7
Authors: Pedrolli F, Morello G, Gesmundo I, Banfi D, Ferro A, Wangpaichitr M, Sha W, Tamagno E, Schally AV, Guglielmotto M, Granata R
PubMed: 41946684
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A Mobile App-Based Individualized Nonpharmacological Intervention for Behavioral and Psychological Symptoms in Dementia: Pilot Randomized Controlled Trial.

JMIR Mhealth Uhealth. 2026 Apr 7;14:e79469.
Authors: Cho E, Yang M, Hwang S, Kim E, Cho J, Kim MJ
PubMed: 41945646
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Revisiting the inverse relationship between breast cancer and Alzheimer's disease: insights and implications.

Neuroepidemiology. 2026 Apr 7;:1-9. Epub 2026 Apr 7
Authors: Zhang Y, Deng Q
PubMed: 41945476
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Discovery of the First Brain-Penetrant Radioligands for Visualizing the GABA Transporter 1 (GAT-1): Synthesis, In Vitro Screening, and In Vivo Evaluation in Nonhuman Primates.

J Med Chem. 2026 Apr 7; Epub 2026 Apr 7
Authors: Gu J, Wang C, Gobbi L, Honer M, Zheng MQ, Gravel P, Gao H, Zhang L, Ropchan J, Nabulsi N, Borroni E, Tamagnan G, Carson R, Huang Y
PubMed: 41945380
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Peptide-based therapeutics in the management of Alzheimer's disease (AD) and their potential to develop novel strategies.

Metab Brain Dis. 2026 Apr 7;41(1)
Authors: Nabi SU, Rasool I, Khan A, Haq AU, Hussain I, Khan MS, Majid S, Rashid S, Rashid SM, Sehar N, Rather MA, Rehman MU
PubMed: 41945238
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Are cognitive subtleties too subtle to see? A diffusion tensor imaging validation of the subtle cognitive impairment test and other psychometric assessments in a normative sample.

Brain Imaging Behav. 2026 Apr 7;20(2)
Authors: Croall ID, Armitage PA, Hadjivassiliou M, Hoggard N
PubMed: 41945187
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The role of 2-Oxoglutarate dehydrogenase complex mitochondrial enzyme in alzheimer's disease: a literature review and bioinformatics workflow.

Metab Brain Dis. 2026 Apr 7;41(1)
Authors: Sayehmiri F, Parvenous M, Vakili K, Ebrahimi R, Batool Z, Bazgir N, Kazemi K, Moafi M, Ebrahimi MJ, Hajiesmaeili M
PubMed: 41945181
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Disodium cromoglycate restricts human tau hyperphosphorylation and manifestation of associated phenotypes by inhibiting GSK3β activity in Drosophila disease models.

Mol Biol Rep. 2026 Apr 7;53(1)
Authors: Kalita BR, Sarkar S
PubMed: 41945164
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Mechanistic Insights into Bergapten by Modulation of Filamin A and GSK3β in STZ Induced Alzheimer's Disease: An Integrated In Silico, In Vitro and In Vivo Study.

Neurochem Res. 2026 Apr 7;51(2)
Authors: Riaz M, Qadir H, Noman M, Ahmed S, Shah FA, Malik MU, Bashir K, Farooq U, Irshad N
PubMed: 41944966
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Associations between air pollution and markers of neuroinflammation, synaptic dysfunction and core Alzheimer's disease pathology vary by APOE genotype.

Neurotox Res. 2026 Apr 7;44(2)
Authors: Kimura K, Driscoll I, Cook N, Shahzad S, Betthauser TJ, Johnson SC, Asthana S, Gallagher CL, Hermann BP, Sager MA, Blennow K, Zetterberg H, Carlsson CM, Kollmorgen G, Okonkwo OC
PubMed: 41944915
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Music therapy interest in patients with Alzheimer's disease and Alzheimer's disease related dementia: A survey study.

J Alzheimers Dis. 2026 Apr 7;:13872877261437271. Epub 2026 Apr 7
Authors: Hemmy L, Cevasco-Trotter A, Silverman M, Wang S, Yuan SH
PubMed: 41944428
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Brain and Liver Dual-Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy.

Adv Sci (Weinh). 2026 Apr 7;:e23458. Epub 2026 Apr 7
Authors: Gong W, Hui W, Qiao S, Ji Q, Liu M, Zhang B, Liu D, Wu Y, Zhou S
PubMed: 41944296
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CSF alpha-Synuclein Seed Amplification Assay results in routine clinically collected samples.

J Parkinsons Dis. 2026 Apr 7;:1877718X261431201. Epub 2026 Apr 7
Authors: Dinter E, Margraff JL, Schniewind I, Reinhard N, UKD SAA study group, Reichmann H, Bräuer S, Falkenburger BH
PubMed: 41944207
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Dementia Incidence in Individuals With Parkinson's Disease in the Framingham Heart Study.

Ann Clin Transl Neurol. 2026 Apr 7; Epub 2026 Apr 7
Authors: Dookhy J, Cummings M, Price E, Liu Y, Gutierrez-Gomez S, O'Shea S, Frank S, Au R, Gurnani AS, Ang TF, Mez J, Shih LC
PubMed: 41944089
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Structural MRI phenotyping in Alzheimer's disease: Comparison of visual rating scales, volumetry, and cortical thickness in a Serbian single-centre cohort.

Biomol Biomed. 2026 Apr 7; Epub 2026 Apr 7
Authors: Aracki-Trenkic A, Živanović M, Milošević V, Bašić J, Radovanović D, Malobabić M
PubMed: 41943971
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Late-life body mass index and amyloid interaction on cognitive decline in unimpaired older adults.

J Prev Alzheimers Dis. 2026 Apr 7;13(5):100543. Epub 2026 Apr 7
Authors: Yau WW, Raman R, Chhatwal J, Pruzin JJ, Shirzadi Z, Aggarwal N, Brickman AM, Cogswell PM, Graff-Radford J, Pillai JJ, Vemuri P, Rafii MS, Yaari R, Aisen P, Sperling R, A4 and LEARN Study Teams
PubMed: 41950544
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Integration of aged brain multi-omics reveals cross-system mechanisms underlying Alzheimer's disease heterogeneity.

Cell Rep. 2026 Apr 7;45(4):117235. Epub 2026 Apr 7
Authors: Scheidemantel LP, de Paiva Lopes K, Gaiteri C, Menon V, De Jager PL, Schneider JA, Buchman AS, Wang Y, Tasaki S, Raittz RT, Bennett DA, Vialle RA
PubMed: 41950003
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Association of epigenetic age acceleration with MRI biomarkers of aging and Alzheimer's disease neurodegeneration.

Aging (Albany NY). 2026 Apr 7;18(1):303-326. Epub 2026 Apr 7
Authors: McEvoy LK, Zhang B, Nguyen S, Maihofer AX, Nievergelt CM, Casanova R, Horvath S, Lu AT, Davatzikos C, Erus G, Resnick SM, Espeland MA, Rapp S, Beckman K, Ferrucci L, LaCroix AZ, Shadyab AH
PubMed: 41949889
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Goat Milk Fat Globule Membrane Supplementation Ameliorates Alzheimer Disease Cognitive Impairment by Modulating the Gut Microbiota.

J Agric Food Chem. 2026 Apr 7; Epub 2026 Apr 7
Authors: Li H, Zhao Y, Luo Y, Bao B, Hao J, Duan S, Liu Z
PubMed: 41947394
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Correction: The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes.

Acta Neuropathol Commun. 2026 Apr 7;14(1)
Authors: Lasagna-Reeves CA, Sengupta U, Castillo-Carranza D, Gerson JE, Guerrero-Munoz M, Troncoso JC, Jackson GR, Kayed R
PubMed: 41947217
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Disruption of the OPTN-TBK1 axis impairs autophagosome formation in prion disease.

Life Sci. 2026 Apr 7;:124381. Epub 2026 Apr 7
Authors: Wang J, Wen P, Sun Z, Gou F, Fan Q, He Y, Zhao D, Yang L
PubMed: 41956418
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From comorbidity to continuum: Alzheimer's disease and epilepsy are connected-now what?

Neurosci Biobehav Rev. 2026 Apr 7;:106682. Epub 2026 Apr 7
Authors: Alves SS, Manzine PR, Dos Santos FM, Migliaccio MM, de Carvalho Alves LV, da Silva Junior RM, Becerra-Hernández LV, González-Acosta CA, Buriticá-Ramírez E, Cominetti MR, Camins A, Garcia-Cairasco N
PubMed: 41956234
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The efficacy and safety of Yokukansan for concomitant behavioral and psychological symptoms of Alzheimer's disease: a randomized, double-blinded clinical trial.

J Ethnopharmacol. 2026 Apr 7;:121644. Epub 2026 Apr 7
Authors: Yuan M, Gu C, Nguyen TT, Xu L, Chen X, Sun J, Zhong L, Zheng Y, Zhang L, Lu Q, Yuan C, Xu H
PubMed: 41956228
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The Role and Therapeutic Potential of DNA Glycosylases in Alzheimer's Disease.

Ageing Res Rev. 2026 Apr 7;:103129. Epub 2026 Apr 7
Authors: Zhao X, Li Y, Meng Z, Xu X, Chen L, Yu Q, Wang R, Ren Y, Chen F, Ai Q, Deng Y, Yu H, Wei J, Liang G
PubMed: 41956137
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Drug Repurposing in Alzheimer's Disease: Emerging Therapeutic Strategies and Promising Candidates.

Ageing Res Rev. 2026 Apr 7;:103113. Epub 2026 Apr 7
Authors: More PS, Rangari SW, Lade SN, Unidrwade DS, Burle SS, Umekar MJ, Lohiya RT, Zanwar AS
PubMed: 41956136
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Psychological Research on Alzheimer's Disease in Pakistan: A Systematic Review of Current Trends and Research Gaps.

Ageing Res Rev. 2026 Apr 7;:103132. Epub 2026 Apr 7
Authors: Aurooj A, Emmanuel S, Jabeen M, Minhaj D, Kirmani SK, Aurooj T, Kafeel SR
PubMed: 41956134
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Triangulating Causal Evidence on Sleep and Dementia.

Sleep. 2026 Apr 7; Epub 2026 Apr 7
Authors: Jiang K, Callow DD, Spira AP
PubMed: 41954951
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The electrophysiological basis of resting-state fMRI hyperconnectivity in early Alzheimer's disease.

Alzheimers Res Ther. 2026 Apr 6; Epub 2026 Apr 6
Authors: Spruyt L, Mlinarič T, Dusart N, Reinartz M, Van Hulle MM, Sunaert S, Van Laere K, Dupont P, Vandenberghe R
PubMed: 41943113
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Moderating role of executive function in the relationship between specific white matter changes and long-term delayed recall in aMCI patients.

Alzheimers Res Ther. 2026 Apr 6; Epub 2026 Apr 6
Authors: Li LL, Ma J, Wu JJ, Xue X, Sun YY, Hua XY, Guo QH, Xu JG
PubMed: 41943102
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Impact of zervimesine on the neuroinflammatory biomarker GFAP and related proteomic molecular correlates in plasma of participants from a phase 2 clinical trial in Alzheimer's disease.

Alzheimers Res Ther. 2026 Apr 6; Epub 2026 Apr 6
Authors: Di Caro V, Cho E, Thiel J, Lizama BN, Koel-Simmelink MJ, Pandey K, Duong D, Seyfried NT, Grundman M, Teunissen CE, Zetterberg H, Blennow K, Caggiano AO, Hamby ME
PubMed: 41943055
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Can supermicrosurgery treat Alzheimer's disease? - Current evidence and hope.

Head Face Med. 2026 Apr 6; Epub 2026 Apr 6
Authors: Rashad A, Hinrichs-Puladi B, Wieker H, Berens J, Ulbrich M, Röhrig R, Hölzle F, Reetz K, Klein M
PubMed: 41943029
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Non-cognitive symptoms as early indicators of Dementia: a preliminary retrospective study from a Psychiatric outpatient clinic.

BMC Psychiatry. 2026 Apr 6; Epub 2026 Apr 6
Authors: Li Y, Xu D, Gu C, Yang L, Jiang Y, Su N, Hong B, Liu Y, Li X, Xiao S, Yue L
PubMed: 41942959
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Efficacy of digital cognitive stimulation therapy for people with dementia: a systematic review and meta-analysis.

BMC Geriatr. 2026 Apr 6; Epub 2026 Apr 6
Authors: Saragih ID, Hwang P, Yadav D, Qiu L, Fick DM, Sundar SS, Abdullah S
PubMed: 41942923
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Contribution of health history and neuropathologic changes to the likelihood of dementia in those with intermediate/high Alzheimer's pathology: findings from The 90 + Study.

Acta Neuropathol. 2026 Apr 6;151(1)
Authors: Melikyan ZA, Al-Darsani Z, Jiang L, Colcord KA, Paganini-Hill A, Bukhari SA, Montine TJ, Kawas CH, Corrada MM
PubMed: 41942821
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Alzheimer's disease risk protein SorLA regulates ER homeostasis and lipid metabolism in human microglia, with conserved effects in neurons.

Acta Neuropathol. 2026 Apr 6;151(1)
Authors: Haq I, Ngo JC, Roy N, Lee E, Choudhury MA, Soni RK, Teich AF, Mayeux RP, De Jager PL, He Y, Wu X, Bennett DA, Olah M, Sher F
PubMed: 41942750
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Author Correction: Consuming a modified Mediterranean ketogenic diet reverses the peripheral lipid signature of Alzheimer's disease in humans.

Commun Med (Lond). 2026 Apr 6;6(1)
Authors: Neth BJ, Huynh K, Giles C, Wang T, Mellett NA, Duong T, Blach C, Schimmel L, Register TC, Blennow K, Zetterberg H, Batra R, Schweickart A, Dilmore AH, Martino C, Arnold M, Krumsiek J, Han X, Dorrestein PC, Knight R, Meikle PJ, Craft S, Kaddurah-Daouk R
PubMed: 41942725
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Differentiating Alzheimer's disease and vascular dementia via combined OCT and OCT‑angiography analysis.

Sci Rep. 2026 Apr 6; Epub 2026 Apr 6
Authors: Ceylan S, Çalışkan ME, Çelik N, Atalay E
PubMed: 41942574
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A single-nucleus RNA-seq dataset of the colon in Pink1-deficient and wild-type mice.

Sci Data. 2026 Apr 6; Epub 2026 Apr 6
Authors: Junaid M, Park SJ, Bae Y, Lee EJ, Bin Lim S
PubMed: 41942478
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Sex-Specific regional brain activity and cognitive function in mild cognitive impairment: An rs-fMRI study.

Transl Psychiatry. 2026 Apr 6; Epub 2026 Apr 6
Authors: Liu Q, Chen B, Su T, Wang Q, Xu D, Yang M, Lin G, Zeng Y, Lao J, Liang S, Li J, Yao K, Xiao Z, Gao P, Zheng X, Zhong X, Ning Y
PubMed: 41942447
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Temporal dynamics of cognitive functioning in people with Parkinson's disease.

NPJ Parkinsons Dis. 2026 Apr 6;12(1)
Authors: Scharfenberg D, Kalbe E, Ophey A, Balzer-Geldsetzer M, Berg D, Hilker-Roggendorf R, Kassubek J, Liepelt-Scarfone I, Mollenhauer B, Reetz K, Riedel O, Roeske S, Schulz JB, Storch A, Trenkwalder C, Witt K, Dodel R, Deserno MK
PubMed: 41942434
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Association of circulating branched-chain or aromatic amino acids based on metabolome and apolipoprotein E genotype with incident dementia: a large cohort study.

Int J Food Sci Nutr. 2026 Apr 6;:1-11. Epub 2026 Apr 6
Authors: Liu Z, Ai Y, Wu Y, Zhang Y, Hua J, Liu T, Liu D, Chen GC, Xu G, Chen LH
PubMed: 41942124
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Positional Prompts-Enhanced Brain-Heart-Gut Interactions for Mild Cognitive Impairment Diagnosis.

IEEE Trans Med Imaging. 2026 Apr 6;PP Epub 2026 Apr 6
Authors: Li F, Zhao S, Bai S, Jia D, Xie F, Liang J, Zhang H, Zhang Y, Ding Z, Xu Y, Sun K, Shen D
PubMed: 41941822
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Controlled Seeding of β-Amyloid Fibrillation Reveals Propagation of Structural Polymorphisms in Cellular Environments.

Biochemistry. 2026 Apr 6; Epub 2026 Apr 6
Authors: Wang T, Sun Y, Lin YR, Yao L, Qiang W
PubMed: 41941608
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Advancing Precision Dementia Care With Genetic-Exposome Risk Assessment.

JAMA Neurol. 2026 Apr 6; Epub 2026 Apr 6
Authors: Andrews SJ, Yaffe K
PubMed: 41941206
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Cognitive health on the fingertips: Fine motor deficiencies for assessing the risk of mild cognitive impairment in the aging adults.

Neuropsychology. 2026 Apr 6; Epub 2026 Apr 6
Authors: Zhao Y, Zhang J, Zhao Y, Yuan Y, Shen J, Peng H, Li J
PubMed: 41941131
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Normative data and clinical validity of verb and phonemic fluency tasks in Turkish-speaking older adults.

Neuropsychology. 2026 Apr 6; Epub 2026 Apr 6
Authors: Tosun S, Karalı FS, Eskioğlu Eİ, Çavdar D, Dicle M, Çınar N, Macoir J
PubMed: 41941130
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Correction: Revisiting Parkinson's disease definition and classification: insights from two emerging biological frameworks.

J Neural Transm (Vienna). 2026 Apr 6; Epub 2026 Apr 6
Authors: Reyes NG, Pajo AT, Saranza G, Höglinger GU, Lang AE
PubMed: 41940965
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Genetic and environmental risk factors of Parkinsonism.

J Neural Transm (Vienna). 2026 Apr 6; Epub 2026 Apr 6
Authors: Kanovsky P, Mensikova K, Cupr P, Vodicka R, Kolarikova K, Strnadova T, Cook SE, Sebelova-Konickova D, Klanova J, Colosimo C, Rosales R
PubMed: 41940964
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From periodontitis to neurodegeneration: Can probiotics modulate the P. gingivalis-amyloid pathway in Alzheimer's disease?

J Alzheimers Dis. 2026 Apr 6;:13872877261432686. Epub 2026 Apr 6
Authors: Sharif-Askari Z, Atoui K, El Zein W, Rizk M, Sharif Askari E
PubMed: 41940869
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Time-restricted eating in Alzheimer's disease (TREAD): A call for research.

J Alzheimers Dis. 2026 Apr 6;:13872877261438520. Epub 2026 Apr 6
Authors: Geda YE, Krell-Roesch J, Bekele K, Gunning JA, Zaniletti I, Eagan D, Demeke M, Khan N, Chahal G, Smith T, DeCuna C, Aliskevich EL, Hettiwatte Y, Ransdell M, Racette SB
PubMed: 41940859
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Sex differences in cognitive performance in Alzheimer's disease: Insights from the ADAS-Cog-13.

J Alzheimers Dis. 2026 Apr 6;:13872877261440125. Epub 2026 Apr 6
Authors: Liu M, Bhatt K, Giaever MF, Ardekani BA, Reichert Plaska C, Alzheimer's Disease Neuroimaging Initiative, Ghanbarian E
PubMed: 41940855
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Apolipoprotein E proteotyping as a valid alternative to genotyping in clinical practice.

J Alzheimers Dis. 2026 Apr 6;:13872877261438522. Epub 2026 Apr 6
Authors: Alcalá Ramírez Del Puerto JM, Ortega-Madueño I, Gil-Moreno MJ, Abizanda-Saro P, Palacios-Sarmiento M, Millán-Guirado R, Cruz-Cárdenas M, Matías-Guiu JA
PubMed: 41940854
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Persistent functional impairment as a preclinical signal of Alzheimer's disease: Advancing dementia prognostication through the natural history of function.

J Alzheimers Dis. 2026 Apr 6;:13872877261438521. Epub 2026 Apr 6
Authors: de Levante Raphael D
PubMed: 41940849
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A Bayesian classification model for differential diagnosis of Alzheimer's disease and frontotemporal dementia using plasma biomarkers.

J Alzheimers Dis. 2026 Apr 6;:13872877261439950. Epub 2026 Apr 6
Authors: Costa T, Liloia D, Premi E, Ashton N, Zettemberg H, Blennow K, Padovani A, Borroni B
PubMed: 41940846
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CeRNA regulatory network of cerebral microvascular dysfunction in early development of APP/PS1 mice model of Alzheimer's disease.

J Alzheimers Dis. 2026 Apr 6;:13872877261435563. Epub 2026 Apr 6
Authors: Gu Q, Xie Y, Zhao Z, Zhuang Z, Yang L, Huang H, Li H, Pi S, Chen F, Gong C, He Y
PubMed: 41940832
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Plasma lipid trajectories improve prediction of future Alzheimer's disease.

J Alzheimers Dis. 2026 Apr 6;:13872877261435212. Epub 2026 Apr 6
Authors: Zou H, Wang T, Huynh K, Meikle PJ, Kaddurah-Daouk R, Luo S, Alzheimer's Disease Neuroimaging Initiative, Alzheimer's Disease Metabolomics Consortium
PubMed: 41940830
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Uncovering polygenic and local genetic overlap between sarcopenia and Alzheimer's disease.

J Alzheimers Dis. 2026 Apr 6;:13872877261436016. Epub 2026 Apr 6
Authors: Ding K, Jiang W, Lei M, Gao Y
PubMed: 41940827
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Distinct patterns of microstructural brain changes in Alzheimer's disease subtypes: Diffusion MRI metrics in braak stage-related regions.

J Alzheimers Dis. 2026 Apr 6;:13872877261436754. Epub 2026 Apr 6
Authors: Hayakawa N, Takeda S, Takahashi H, Arisawa A, Matsuo C, Tomiyama N, Nakajima T, Miki S, Kishino Y, Teshirogi S, Yamamoto S, Okawara M, Ito Y, Takami Y, Takeya Y, Yamamoto K, Morishita R
PubMed: 41940826
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Baseline cortical amyloid-β levels are associated with subsequent study-partner-rated apathy in community-dwelling older adults.

J Alzheimers Dis. 2026 Apr 6;:13872877261436755. Epub 2026 Apr 6
Authors: Munro CE, Beltran J, Palmer P, Farrell M, Hanseeuw B, Rentz DM, Buckley R, Properzi M, Vannini P, Amariglio RE, Quiroz YT, Yang HS, Blacker D, Sperling RA, Johnson KA, Marshall GA, Gatchel JR
PubMed: 41940821
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Functional connectivity alterations in objectively defined subtle cognitive decline: A cross-sectional functional MRI study in cognitively healthy older adults.

J Alzheimers Dis. 2026 Apr 6;:13872877261435619. Epub 2026 Apr 6
Authors: Sigg-Alonso J, Mondragón JD, González-López M, Pasaye Alcaraz EH, Fernández T
PubMed: 41940817
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The value and risks of antidepressant therapy in Alzheimer's disease: a field update and its clinical implications.

Expert Rev Neurother. 2026 Apr 6;:1-15. Epub 2026 Apr 6
Authors: Rus Prelog P, Kores Plesničar B, Zupan M, Frol S, Kramberger MG
PubMed: 41940797
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Feasibility of Craniofacial Vascular Lymph Node Transfer for Augmented Glymphatic Drainage in Rodents.

Cleft Palate Craniofac J. 2026 Apr 6;:10556656261438277. Epub 2026 Apr 6
Authors: Andrews BT, Zanaty M, Pierson SR, Fiock KL, Howard MA, Hansen MR, Yin TC
PubMed: 41940537
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Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy.

Adv Healthc Mater. 2026 Apr 6;:e04608. Epub 2026 Apr 6
Authors: Salim MW, Zhang W, Collins-Praino L, Wang Y, Care A
PubMed: 41937703
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A scoping review of frontal cortex tDCS on neuropsychological functioning in older adults with mild cognitive impairment and Alzheimer's Clinical Syndrome.

Int Rev Psychiatry. 2026 Apr 6;:1-17. Epub 2026 Apr 6
Authors: Helphrey JH, Hart J, McClintock SM, Peters ME, Thakkar VJ, LoBue C
PubMed: 41937689
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Corrigendum to Diffusion MRI measures detect brain microstructure changes due to early treatment with neurotrophic peptide mimetic P021 in the 3xTg-AD mouse model of Alzheimer's disease. Magn Reson Imaging. 2026 Jun;129:110641 Page: 9.

Magn Reson Imaging. 2026 Apr 6;:110677. Epub 2026 Apr 6
Authors: Falangola MF, Voltin J, Cole M, Nietert PJ, Liu F, Iqbal K, Jensen JH
PubMed: 41945082
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Voice Biomarkers: Cognitive Impairment, including Alzheimer's Disease, Dementia, or Mild Cognitive Impairment: Introduction to Peripheral Neuropathy.

Curr Alzheimer Res. 2026 Apr 6; Epub 2026 Apr 6
Authors: Özcan F
PubMed: 41944116
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Pathophysiological Role of the Gut Brain Axis in Parkinson's Disease: From Microbial Metabolites and Intestinal Permeability to Central Neuroinflammation.

Curr Neurovasc Res. 2026 Apr 6; Epub 2026 Apr 6
Authors: Saini O, Kaur A, Haneef M, Kosey S
PubMed: 41944109
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Associations between TMEM106B C-terminal fragment aggregation, age, and TDP-43 or tau pathology.

Brain Pathol. 2026 Apr 6;:e70090. Epub 2026 Apr 6
Authors: Acewicz A, Tarka S, Grzegorczyk M, Rzepliński R, Wierzba-Bobrowicz T, Stępień T
PubMed: 41943532
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Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival.

Ann Clin Transl Neurol. 2026 Apr 6; Epub 2026 Apr 6
Authors: Beers DR, Lin YY, Thonhoff JR, Thome AD, Faridar A, Zhao W, Wen S, Appel SH
PubMed: 41943205
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Factors related to cognitive reserve: A comparative analysis of education, occupation, lifestyle, and social network factors based on brain measures.

J Gerontol B Psychol Sci Soc Sci. 2026 Apr 6; Epub 2026 Apr 6
Authors: Sun H, Perry B
PubMed: 41950393
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Alzheimer's disease staging using enhanced inception-ResNet-V2 and improved XceptionNet models for 3D MRI classification and segmentation.

J Neurosci Methods. 2026 Apr 5;432:110767. Epub 2026 Apr 5
Authors: Srilakshmi V, Devarasetty P, Chetana VL, Vinta S, Kowtharapu R
PubMed: 41941947
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[18F]Fluorodeoxyglucose positron emission tomography ([18F]FDG PET) Characterizes Neurodegeneration Levels Across the α-Synucleinopathy Continuum.

Mov Disord. 2026 Apr 5; Epub 2026 Apr 5
Authors: Orso B, Roura I, Mattioli P, Famà F, Massa F, Lorenzini L, Brugnolo A, Girtler N, Losa M, Raffa S, Sofia L, Roascio M, Arnulfo G, Morbelli S, Pardini M, Arnaldi D
PubMed: 41937449
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Neurogenesis as a Biomarker of Disease Modification in Parkinson's Disease.

Mov Disord. 2026 Apr 5; Epub 2026 Apr 5
Authors: Munir I, Noor G, Soomro MI
PubMed: 41937378
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Corrigendum to "IL-34 exacerbates pathogenic features of Alzheimers disease and calvaria osteolysis in triple transgenic (3x-Tg) female mice" [Biomed. Pharmacother. 166 (2023) 115435].

Biomed Pharmacother. 2026 Apr 4;:119293. Epub 2026 Apr 4
Authors: Ho A, Ngala B, Yamada C, Garcia C, Duarte C, Akkaoui J, Ciolac D, Nusbaum A, Kochen W, Efremova D, Groppa S, Nathanson L, Bissel S, Oblak A, Kacena MA, Movila A
PubMed: 41936484
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Amyloid-related imaging abnormalities in Japanese patients with Alzheimer's disease treated with Lecanemab: A real-world study.

J Prev Alzheimers Dis. 2026 Apr 4;13(6):100562. Epub 2026 Apr 4
Authors: Shimasaki R, Kurihara M, Bannai T, Hatano K, Suzuki F, Tokumaru AM, Ishii K, Ihara R, Iwata A
PubMed: 41936348
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Barriers and facilitators to recruitment, engagement, and retention of underrepresented populations in dementia prevention research: a scoping review.

J Prev Alzheimers Dis. 2026 Apr 4;13(6):100557. Epub 2026 Apr 4
Authors: Rirash AF, Franzen S, Bourdage R, Kreuk E, Visser NC, Babulal GM, van den Berg E, Papma JM
PubMed: 41936347
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LADNET: An MRI-based deep learning approach for Alzheimer's disease detection.

Comput Biol Med. 2026 Apr 4;208:111647. Epub 2026 Apr 4
Authors: Ullah U, Habib S, Islam M
PubMed: 41936289
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Environmental sound processing in primary progressive aphasia: behavioral deficits and their neural correlates.

Brain Cogn. 2026 Apr 4;195:106430. Epub 2026 Apr 4
Authors: Kawakami N, Ota S, Ogawa N, Kakinuma K, Katsuse K, Matsubara S, Morihara K, Kobayashi E, Kawamura A, Kikuchi H, Iseki C, Takanami K, Kanno S, Suzuki K
PubMed: 41936230
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Trajectories of frailty, grip strength and gait speed preceding dementia: a nested case-control study.

Age Ageing. 2026 Apr 4;55(4)
Authors: Wu Z, Phyo AZ, Cribb L, Vishwanath S, Orchard SG, Owen A, Woods R, Chong TT, Wolfe R, Shah RC, Sheets K, Murray A, Ryan J
PubMed: 41936045
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AI guided discovery of a murine model of asymptomatic Alzheimer's disease.

Acta Neuropathol Commun. 2026 Apr 4; Epub 2026 Apr 4
Authors: Jati S, Taheri S, Kal S, Sinha SC, Head BP, Mahata SK, Sahoo D
PubMed: 41935326
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Neuronal HDAC9: A key regulator of cognitive and synaptic aging, rescuing Alzheimer's disease-related phenotypes.

Mol Psychiatry. 2026 Apr 4; Epub 2026 Apr 4
Authors: Lei Y, Chen Y, Guo M, Patel F, Bai Y, Goo B, Du Q, Weintraub NL, Lu XY
PubMed: 41935184
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Baicalein alleviates Alzheimer's disease pathology in AD models by activating the PI3K/AKT/GSK3β pathway to inhibit neuronal apoptosis.

Sci Rep. 2026 Apr 4; Epub 2026 Apr 4
Authors: Cheng W, Yang S, Lu Y, Wang Y, Tan AH
PubMed: 41935181
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Inhibitory effect of epigallocatechin-3-gallate as a potent anti-amyloidogenic agent against the G138E mutant of SOD1.

Sci Rep. 2026 Apr 4; Epub 2026 Apr 4
Authors: Sheikhpour Z, Seyedalipour B, Ataei F, Baziyar P, Akhlaghi M, Hosseinkhani S
PubMed: 41935163
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DNAJC6 Parkinson's disease: Endolysosomal dysfunction and emerging roles for oligodendrocytes.

NPJ Parkinsons Dis. 2026 Apr 4; Epub 2026 Apr 4
Authors: Allen AG, Stednitz S, Lardelli M, Barthelson K
PubMed: 41935042
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The role of olfactory and salivary gland pathways in periodontal disease-mediated Alzheimer's disease progression: mechanistic insights and early diagnostic implications.

Acta Clin Belg. 2026 Apr 4;:1-17. Epub 2026 Apr 4
Authors: Liang H, Yu W, Han Z, Xu B, Zhuang Z, Liu J
PubMed: 41934639
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STFusion: A Spatial-Temporal Dual-Pathway Network with Multi-scale Attention Fusion for Early Diagnosis of Parkinson's Disease.

Interdiscip Sci. 2026 Apr 4; Epub 2026 Apr 4
Authors: Yue H, Kuang H, He M, Li J, Wang Y, Wang J
PubMed: 41934528
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Abnormal cortical hierarchy revealed by gradient dysfunction in patients with definite amyotrophic lateral sclerosis.

Brain Res Bull. 2026 Apr 4;239:111850. Epub 2026 Apr 4
Authors: Cai ZW, Zhuang SP, Huang ZY, Shi JY, Huang NX, Chen S, Zou ZY, Chen HJ
PubMed: 41941997
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Characterisation of a patient-derived iPSC-based model for studying the blood-brain barrier in Alzheimer's disease.

Brain Res Bull. 2026 Apr 4;239:111872. Epub 2026 Apr 4
Authors: Wagner S, Danz K, Hyvärinen J, Fischer AL, Kanninen KM, Gynther M, Puris E
PubMed: 41941996
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A specific Pilose antler peptide LVLVEAELRE ameliorates cognitive deficits in SAMP8 mice via Celsr2.

J Ethnopharmacol. 2026 Apr 4;:121649. Epub 2026 Apr 4
Authors: Sun Z, Peng Q, Qiu C, Jia X, Wang H, Wu S, Tao W
PubMed: 41941989
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Intelligent delivery of autophagy-targeting chimeric peptides by engineered exosomes for the degradation of a-synuclein.

Acta Biomater. 2026 Apr 4; Epub 2026 Apr 4
Authors: Zeng Y, Lv Z, Liang J, Wu Y, Han L
PubMed: 41941974
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Ferroptosis-related mechanisms in prion diseases provide insights into neurodegeneration and reveal therapeutic implications.

Redox Biol. 2026 Apr 4;93:104155. Epub 2026 Apr 4
Authors: Zayed M, Tayara H, Jeong BH
PubMed: 41945998
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Microstates to modulation: EEG signatures guiding clinical translation in dementia.

Clin Neurophysiol. 2026 Apr 4;:2111876. Epub 2026 Apr 4
Authors: Noda Y
PubMed: 41951467
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The m7G modification: An emerging player in neurological diseases.

Pathol Res Pract. 2026 Apr 4;282:156465. Epub 2026 Apr 4
Authors: Song Y, Zhao Z, Dai Y, Li C, He X, Wang Y, Xu ZD, Yang Y
PubMed: 41955837
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Sex differences for clinical presentations and co-pathologies in four-repeat tauopathies.

Biol Sex Differ. 2026 Apr 3; Epub 2026 Apr 3
Authors: Bayram E, Carter DJ, Aslam S, Forbes E, Holden SK
PubMed: 41933395
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Targeting the HDAC4-NHE6-endosomal pH axis restores amyloid-β clearance and cognitive function in Alzheimer's disease mice.

J Nanobiotechnology. 2026 Apr 3; Epub 2026 Apr 3
Authors: Huang N, Hong R, Cui X, Cao L, Shi L, Chen B, Su Y, Xu X, Hua C, Ying T
PubMed: 41933339
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Neuronal APOE4-induced early hippocampal network hyperexcitability in Alzheimer's disease pathogenesis.

Nat Aging. 2026 Apr 3; Epub 2026 Apr 3
Authors: Tabuena DR, Jang SS, Grone B, Yip O, Aery Jones EA, Blumenfeld J, Liang Z, Mann RS, Li Y, Necula D, Koutsodendris N, Rao A, Ding L, Zhang AR, Hao Y, Xu Q, Yoon SY, De Leon S, Huang Y, Zilberter M
PubMed: 41933197
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Target product profiles for treatments to delay or prevent symptomatic Alzheimer's disease.

Nat Med. 2026 Apr 3; Epub 2026 Apr 3
Authors: Cummings JL, Agadjanyan MG, Barry M, Corey L, Doody R, Hendrix S, Mattke S, Mattsson-Carlgren N, McDade E, Menetski JP, Mohs RC, Partrick KA, Petrovsky N, Selkoe DJ, Silva D, Sperling RA, Tiede B, Vradenburg G
PubMed: 41933174
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The exposome of brain aging across 34 countries.

Nat Med. 2026 Apr 3; Epub 2026 Apr 3
Authors: Legaz A, Moguilner S, Barttfeld P, Cuadros Castro J, Galván Rial DS, Migeot J, Farina FR, Gonzalez-Gomez R, Salazar-Londoño S, de Souza Azzi T, Alcauter S, Amoruso L, Anghinah R, Bakr M, Behrens MI, Bruno MA, Cardona JF, Chen C, Colliot O, Custodio N, d'Acremont Q, Debette S, Dzianok P, Güntekin B, Huguet J, Jarne C, Joliot M, Karageorgiou E, Khedr EM, Koopowitz SM, Kublik E, Lee J, Aksman L, Lopez S, Margaretic P, Matallana D, Matis S, Miltiadous A, Novotni G, Orio P, Parra MA, Reppermund S, de Paula França Resende E, Salum GA, Slachevsky A, Ortiz AL, Takada LT, Toh AQ, Tzallas A, Wen W, Whelan R, Yener G, Zegarra Valdivia JA, Alexoudi A, Arshad F, Atta H, Avila-Funes JA, Santos JB, Bruña R, Castelblanco-Toro SM, Chino Vilca BN, Coronel-Oliveros C, Crivello F, Cruzat J, Dellavale D, Dhooge C, Di Caterina G, Escudero J, Esquivias Farias JM, Eze LU, Evans TE, Farombi T, Fernández A, Fittipaldi S, Portillo F, Martinic GF, García AM, Garcia-Cordero I, Gaurav R, Godoy ME, Gonzalez Campo C, González Hernández A, Hanoğlu L, Hazelton JL, Herzog R, Ikiz B, Njamnshi AK, Landin-Romero R, López ME, Maito MA, Medel V, Sepúlveda JP, Ochoa Gómez JF, Ogbuagu C, de Oliveira MO, Ozansoy M, Palma-Espinosa J, Hilal S, Zhou JH, Escudero SD, Pitman JK, Prado P, Ramírez González D, Reyes P, Santamaría García H, Schröder J, Sitt JD, Soliman RK, Soto-Añari M, Thanissery N, Ito LT, Tsuchida A, Tzourio C, Yırıkoğulları H, Yokoyama JS, Aguillon D, Miller B, Alladi S, Jiang Y, Navarro A, Babiloni C, Huepe Artigas D, Piguet O, Sosa PA, Mostert CM, Tahmasian M, Li P, Hu K, Genon S, Stein DJ, Maestú F, Pievani M, Salama M, Brodaty H, Sachdev PS, Lawlor B, Eyre HA, Miranda JJ, Baez S, Tagliazucchi E, Duran-Aniotz C, Hernandez H, Ibanez A
PubMed: 41933172
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A pilot study of assessing visual hallucinations using virtual reality in lewy body disorders.

Sci Rep. 2026 Apr 3; Epub 2026 Apr 3
Authors: Hirczy SS, Lin YH, Xiong W, Schrift M, Kojima Y
PubMed: 41933015
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CRISPR-Cas9 and next-generation gene editing strategies for therapeutic intervention of neurodegenerative pathways in Alzheimer's disease: a state-of-the-art review.

Acta Neurol Belg. 2026 Apr 3; Epub 2026 Apr 3
Authors: Khan MS, Zafar I, Jamal A, Bahwerth FS, Khan S, Faizan M, Khan H, Noman M, Okeibunor K, Ahmad A, Zain Ul Abedin M
PubMed: 41931258
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Olfactory Dysfunction Exacerbates Hippocampal Aβ Accumulation, Tau Phosphorylation and Memory Deficits in Mice.

Neurochem Res. 2026 Apr 3;51(2)
Authors: Du M, Ma S, Bai L, Mou X, Gao Y, Zhang J, Chen Y
PubMed: 41931192
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Narrative Review "Dual Frontiers in Neurodegeneration: Pharmacological Synergies and Divergences in Parkinson's Disease and Type 2 Diabetes Mellitus".

Cell Mol Neurobiol. 2026 Apr 3; Epub 2026 Apr 3
Authors: Sharallah OA, Malakar V, Salama AE, Elmaaz SM, Daba SA, Poddar NK
PubMed: 41931123
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Epilepsia partialis continua as the presenting manifestation of Creutzfeldt-Jakob disease: A video-polygraphic clinical vignette.

Epileptic Disord. 2026 Apr 3; Epub 2026 Apr 3
Authors: Cutellè R, Pascarella A, Santoro A, Cianci V, Mammì A, Tripodi GG, Prestandrea C, Gasparini S, Ferlazzo E
PubMed: 41931016
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TREM2 deficiency delays postnatal microglial maturation and synaptic pruning, leading to anxiety-like behaviors.

J Alzheimers Dis. 2026 Apr 3;:13872877261437264. Epub 2026 Apr 3
Authors: Yang HC, Deng YS, Zhang J, Zhang T, Song W, Qin Q, Chen O, Tang Y
PubMed: 41930604
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Inflammation-related miR-155-5p as an APOE ε4-modulated biomarker for amyloid pathology in mild cognitive impairment.

J Alzheimers Dis. 2026 Apr 3;:13872877261437135. Epub 2026 Apr 3
Authors: Yoshida K, Saito N, Takahashi R, Ando S, Kashibayashi T, Fujita J, Takano K, Kowa H, Hashiramoto A
PubMed: 41930593
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Randomized, double-blind study of zervimesine in mild to moderate Alzheimer's disease.

J Alzheimers Dis. 2026 Apr 3;:13872877261437145. Epub 2026 Apr 3
Authors: Vijverberg EG, Scharre DW, Woodward M, Catalano S, Hamby ME, Grundman M, Morgan RE, Iaci J, Devins T, Caggiano AO
PubMed: 41930592
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Herpes zoster, antiviral therapy, and Alzheimer's disease: Turning association into an actionable prevention pathway.

J Alzheimers Dis. 2026 Apr 3;:13872877261438524. Epub 2026 Apr 3
Authors: Qin J, Xu X, Zou Y
PubMed: 41930591
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The role of cannabinoid ligands in neurodegenerative diseases: emerging anti-inflammatory, immunomodulation and disease-modifying perspectives.

Pharmacol Res. 2026 Apr 3;:108185. Epub 2026 Apr 3
Authors: Baldasso GM, Paes RS, Moreira AG, Salvadori SG, Limberger C, Roviezzo F, Capasso R, Dutra RC
PubMed: 41937092
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Decoding the Secretase Puzzle in Amyloid-β Generation: A State-of-the-Art Overview of the Protease-Mediated APP Processing Cascade in Alzheimer's Disease.

Ageing Res Rev. 2026 Apr 3;:103116. Epub 2026 Apr 3
Authors: Senkowska Z, Weglarz-Tomczak E
PubMed: 41936903
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Research Progress on Carotid Artery Changes and Cognitive Impairment in Alzheimer's Disease Patients.

Ageing Res Rev. 2026 Apr 3;:103127. Epub 2026 Apr 3
Authors: Li X, Feng X, Cai A, Guo X, Li J, Liao W, Long H, Luan P
PubMed: 41936902
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Ageing and the lymphatic system: Implications for immunity, brain health, and possible therapeutic interventions.

Ageing Res Rev. 2026 Apr 3;118:103126. Epub 2026 Apr 3
Authors: Rojas Velazquez MN, Gousopoulos E, Wolf S, Zurfluh CE, Lindenblatt N
PubMed: 41936901
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How does social health impact cognitive function and brain reserve? Findings from the SHARED Consortium.

Ageing Res Rev. 2026 Apr 3;:103118. Epub 2026 Apr 3
Authors: Samtani S, Stafford J, Szcześniak D, Brodaty H, Davis D, Ikram MA, Jeon YH, Melis RJ, Patalay P, Perry M, Rymaszewska J, Vernooij-Dassen M, Welmer AK, Wolf-Ostermann K, Maddock J, Marseglia A, SHARED Consortium
PubMed: 41936900
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Cerebrospinal fluid CEFA composition is enriched in saturated fatty acids and it is altered in Alzheimer's Disease.

J Lipid Res. 2026 Apr 3;:101034. Epub 2026 Apr 3
Authors: Pavanello C, Ossoli A, Comi C, Turri M, Tremolizzo L, Conti E, D'Incecco P, Barbiroli A, Parini P, Mitro N, Caruso D, Sierri G, Re F, Chinello C, Fumagalli C, Magni F, Fernandes K, Calabresi L
PubMed: 41936849
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Causal relationships between plasma lipidomics, trace elements, cerebrospinal fluid metabolites, and Parkinson's disease using Mendelian randomization.

Brain Res Bull. 2026 Apr 3;239:111859. Epub 2026 Apr 3
Authors: Wang M, Huang M, Chen Z, Gou S, Ma C, Xiao L
PubMed: 41936801
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Astrocytic FABP5 drives non-cell-autonomous oligodendrocyte injury in multiple system atrophy by promoting TNF signaling and ferroptotic stress.

Redox Biol. 2026 Apr 3;93:104150. Epub 2026 Apr 3
Authors: Wu C, Lin J, Chen Y, Takahashi N, Chen Q, Liu B, Dai F, Zhao W, Finkelstein DI, Kawahata I, Fukunaga K, Cheng A
PubMed: 41936214
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Dementia risk factor assessment in a local Alzheimer's prevention population: a German cross-sectional, observational study.

J Prev Alzheimers Dis. 2026 Apr 3;13(6):100556. Epub 2026 Apr 3
Authors: Sannemann L, Gerards M, Bohr L, Brosseron F, Escher C, Kalthegener F, Müller T, Ramírez A, Zeyen P, Jessen F, Rostamzadeh A
PubMed: 41935406
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Anti-alzheimer Drugs Development and Small Molecules: Mechanistic Understanding of the 5HT₄ and 5-HT₆ Receptor.

Curr Neuropharmacol. 2026 Apr 3; Epub 2026 Apr 3
Authors: Dhanawat M, Malik G, Wilson K, Bhushan B
PubMed: 41935386
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A computational framework for Alzheimer's disease detection using SwinRes Transformer.

Comput Biol Med. 2026 Apr 3;208:111663. Epub 2026 Apr 3
Authors: Parameswari M, Deepa N, Sathya Priya J, Muthulakshmi K
PubMed: 41934938
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Icariin, astragaloside IV and puerarin mixture salvages synaptic loss by enhancing mitochondrial biogenesis: A multi-target strategy for Alzheimer's disease therapy.

Biomed Pharmacother. 2026 Apr 3;198:119320. Epub 2026 Apr 3
Authors: Zhong J, He X, Yang H, Zhang J, Liu J, Yang J, Dong X
PubMed: 41934898
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Chicoric acid enhanced brain cholesterol efflux and reduced Aβ pathology via LXR-ABCA1 signaling in Alzheimer's models.

Neurotherapeutics. 2026 Apr 3;23(3):e00899. Epub 2026 Apr 3
Authors: Li D, Zhang Y, Wang R, Jin L, Cui X, Hong JS, Li S, Zhao J, Guo Y
PubMed: 41934727
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Association of plasma glial fibrillary acidic protein and APOE-ε4 with Alzheimer's disease.

Neurobiol Aging. 2026 Apr 3;164:19-27. Epub 2026 Apr 3
Authors: Zhu Y, Lan G, Li A, Zhang L, Jiang M, Yang J, Zhu J, He Z, Zhou X, Li M, Wang Y, Sun P, Cai Y, Liu Z, Wang YJ, Han Y, Bu G, Guo T
PubMed: 41946261
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P2X7 receptor and neuroinflammation in neurodegenerative disorders: an autoradiography study with [18F]JNJ-64413739.

Nucl Med Commun. 2026 Apr 3; Epub 2026 Apr 3
Authors: Ashok AH, Field S, Ramakrishnan NK, Thompson S, O'Brien JT, Aigbirhio FI
PubMed: 41944714
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Metabolic and inflammatory roles of glial cells in neurodegenerative and cerebrovascular diseases.

Ageing Res Rev. 2026 Apr 2;118:103120. Epub 2026 Apr 2
Authors: Ogunleye FA, Zhou Y, Yan L, Abhulimen PO, Xu Y, Lai MK, Okunowo WO, Sethi G, Fang C, Ma Y
PubMed: 41932503
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Ferulic acid inhibits Tau-441 liquid-liquid phase separation to restore glycolytic metabolism.

Int J Biol Macromol. 2026 Apr 2;358:151806. Epub 2026 Apr 2
Authors: Lin WJ, Li CY, Shi WP, Liu TA, Wang YJ, Li YJ
PubMed: 41932135
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Reliability and validity of the L test in people with Alzheimer's disease.

Geriatr Nurs. 2026 Apr 2;70:104025. Epub 2026 Apr 2
Authors: Ozkan T, Ates-Sari Y, Unluer NO, Hangun SF, Karadas C, Eroglu E
PubMed: 41932058
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MALDI mass spectrometry imaging (MSI) reveals molecular and structural heterogeneity of amyloid-β in sporadic Alzheimer's disease and Down syndrome.

Acta Neuropathol Commun. 2026 Apr 2;14(1)
Authors: Minta K, Söderberg L, Gkanatsiou E, Johannesson M, Möller C, Björklund M, Osswald G, Lannfelt L, Fabre S, Michno W
PubMed: 41928377
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Cost-utility analysis of cerebrospinal fluid versus blood biomarkers for early detection of Alzheimer's disease and mild cognitive impairment in Thailand: a modeling study.

BMC Health Serv Res. 2026 Apr 2; Epub 2026 Apr 2
Authors: Leelahavarong P, Prawjaeng J, Angkab P, Wongkom N, Scheltens P, Srinonprasert V, Senanarong V
PubMed: 41928210
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Early onset Alzheimer's disease with V180I variant of prion protein gene and a family history of dementia: a case report.

BMC Neurol. 2026 Apr 2; Epub 2026 Apr 2
Authors: Hamaguchi T, Hamano T, Senoh T, Kawasaki Y, Uehara T, Satoh K, Hara N, Miyashita A, Ikeuchi T, Kitamoto T, Asahina M
PubMed: 41928108
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Undiagnosed dementia in underserved African American populations: Missed opportunities for care.

Int Psychogeriatr. 2026 Apr 2;:100208. Epub 2026 Apr 2
Authors: Cohen G, Mati MB, Woodward OJ, Hepburn K, Perkins MM
PubMed: 41934033
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TDP-43 multidomains and RNA modulate interactions and viscoelasticity in biomolecular condensates.

Biophys J. 2026 Apr 2; Epub 2026 Apr 2
Authors: Matsushita Y, Yasuda I, Watanabe F, Yamamoto E
PubMed: 41933903
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Clustering hinders APP α-secretase processing in the plasma membrane.

Biophys J. 2026 Apr 2; Epub 2026 Apr 2
Authors: Pinkwart K, Lang T
PubMed: 41933902
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Risk factors for early-onset and late-onset dementia: a prospective cohort study.

Lancet Healthy Longev. 2026 Apr 2;:100831. Epub 2026 Apr 2
Authors: Giorgio K, Stephen JJ, Mansolf M, Peterson EA, Gross AL, Briceño EM, Levine DA, Helmer C, Debette S, Soumaré A, Ikram MA, Wolters FJ, Seshadri S, Satizabal CL, Himali JJ, Launer LJ, Li D, Mbangdadji D, Lloyd-Jones DM, Sorond FA, Zhao L, Lopez OL, Judd SE, Hughes TM, Guðnason V, Aiello AE, Fohner A, Singh-Manoux A, Sabayan B, Pankow JS, de Vries PS, Yaffe K, Beiser A, Dehghan A, Zmora R, Scholtens D, Lutsey PL, Allen NB, MacLehose R, Sedaghat S
PubMed: 41936382
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Association between heterozygous GBA1 L444P carrier status and risk of Parkinson's disease: A systematic review and meta-analysis.

Mol Genet Metab. 2026 Apr 2;148(2):110112. Epub 2026 Apr 2
Authors: Jurecka A, Kim HK, Siegfried N, Zhao YC
PubMed: 41936135
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Transcriptomic dissociation between synaptic plasticity suppression and structure-related maintenance signaling in the Alzheimer's frontal cortex: A molecular analysis.

Behav Brain Res. 2026 Apr 2;508:116202. Epub 2026 Apr 2
Authors: Juanlu C, Chen PS
PubMed: 41935791
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Microglial P2Y12 signaling phase-shifts glymphatic circadian rhythms and alters sleep architecture in mice.

Prog Neurobiol. 2026 Apr 2;261:102911. Epub 2026 Apr 2
Authors: Su L, Tian M, Hao Y, Zhang X, Liu X, Liu L, Yao E
PubMed: 41935776
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Amyloid pathology drives cognitive decline in Alzheimer's disease through impairing neurovascular coupling: An [¹⁸F]-Florbetapir PET/MRI Study.

Brain Res Bull. 2026 Apr 2;239:111863. Epub 2026 Apr 2
Authors: Hao X, Wang X, Liu R, Li Y, Dong C, Liu J
PubMed: 41935672
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Human APOB-expressing mice translate molecular phenotypes across the Alzheimer's disease spectrum.

Brain Behav Immun. 2026 Apr 2;136:106575. Epub 2026 Apr 2
Authors: Aumont-Rodrigue G, Poirier A, Picard C, Poirier J, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 41935644
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Chloride intracellular channel 4 contributes to Aβ-induced cognitive impairment in mice through the regulation of mitochondrial fission. CLIC4 promotes mitochondrial fission.

Cell Signal. 2026 Apr 2;:112499. Epub 2026 Apr 2
Authors: Wang J, Mao X, Zheng R, Gao H, Chen G, Zhang Y, Xu M, Lin Q, Nivar J, Tao YX, Sun M, Cao H, Zhang J, Li J
PubMed: 41935590
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A covalent organic framework nano-chelator orchestrates multitarget clearance of Alzheimer's pathologies.

J Colloid Interface Sci. 2026 Apr 2;717:140451. Epub 2026 Apr 2
Authors: Bai X, Wei Y, Zhao D, Zhang Y, Lian X, Zhang C, Li M
PubMed: 41950681
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Three donor-matched iPSC lines derived from human postmortem dura mater for modeling neurodegenerative diseases.

Stem Cell Res. 2026 Apr 2;94:103984. Epub 2026 Apr 2
Authors: Shim YM, Yoo S, Kwon HJ, Lee K, Park SH, Won JK
PubMed: 41955966
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The hypothalamus is an early site of mitochondrial failure and neuro-immune circuit disruption in amyotrophic lateral sclerosis.

Mol Metab. 2026 Apr 1;:102360. Epub 2026 Apr 1
Authors: Scaricamazza S, Nesci V, Fenili G, Tiberi M, Percio A, Rosina M, Salvatori I, Riggio F, Candelise N, Pieroni L, Greco V, Chiurchiù V, Ferri A, Valle C
PubMed: 41932651
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Blood neurodegeneration biomarkers and the muscle-brain axis in older adults: physical performance as a functional mediator of cognition.

Exp Gerontol. 2026 Apr 1;:113123. Epub 2026 Apr 1
Authors: Ceolin C, Noale M, Musso G, Sturani S, Ravelli A, Simonato C, Busetto L, Antonini A, Fiorenzato E, Montagnana M, Coin A, Devita M, Sergi G, De Rui M, OPA working group
PubMed: 41932588
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Revealing subcellular retinal alterations in 5xFAD B6SJLF1/J mice.

Exp Neurol. 2026 Apr 1;401:115758. Epub 2026 Apr 1
Authors: Giani A, Musi CA, Priori EC, Turchetti S, Passi M, Galbiati S, Viganò I, Bakker N, Klaassen I, Zerbini G, Borsello T, RECOGNISED consortium
PubMed: 41932564
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Dysregulation of Drp1 and Mfn2 is associated with reduced PSD-95, synaptophysin, and BDNF expression in a rat model of Alzheimer's disease.

Int J Biol Macromol. 2026 Apr 1;360:151774. Epub 2026 Apr 1
Authors: Alfateh M, Vasconcelos C, Choker AH, Mohammadaein H
PubMed: 41932483
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Overexpression of miR-455-3p enhances mitophagy, synaptic and mitochondrial proteins in Alzheimer's disease.

Mitochondrion. 2026 Apr 1;89:102151. Epub 2026 Apr 1
Authors: Pradeepkiran JA, Bandaru M, Islam MA, Kshirsagar S, Alvir RV, Mukherjee U, Reddy PH
PubMed: 41932415
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HTRA1 and brain disorders: A balancing act across neurodegeneration and repair.

Prog Neurobiol. 2026 Apr 1;261:102914. Epub 2026 Apr 1
Authors: Hjæresen S, Gramkow ET, Zhang M, Fex Svenningsen Å
PubMed: 41932381
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Generation and characterization of induced pluripotent stem cell lines from one Parkinson's disease patient carrying the GBA1 T369M variant and two variant-free controls.

Stem Cell Res. 2026 Apr 1;93:103983. Epub 2026 Apr 1
Authors: Hosseini Bondarabadi M, Xu M, Slingerland S, de Leeuw J, Sommer I, Harmsen HJ, van Laar T, van Ijzendoorn SC
PubMed: 41932028
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Apolipoprotein E Mimetic Peptide CN-105 and Postoperative Delirium in Older Patients: The Phase 2 MARBLE Randomized Clinical Trial.

JAMA Netw Open. 2026 Apr 1;9(4):e262289.
Authors: Timko NJ, Cooter Wright M, Smith MR, Boykin PC, Emerson JM, Woldorff MG, Eleswarpu S, Herbert JT, Moretti EW, Devinney MJ, Ayoub CM, Rockhold FW, Ryu D, Syed A, VanDusen KW, Bunning T, Hsia BJ, Bolognesi MP, Jiranek WA, Zetterberg H, Blennow K, Huebner JL, Li Z, Reekes TH, Browndyke JN, Laskowitz DT, Berger M, MARBLE Study Investigators
PubMed: 41931297
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Neutrophil inflammation metrics are associated with the risk of future dementia in large data from NYU Langone Hospitals and the Veterans Health Administration.

Alzheimers Dement. 2026 Apr;22(4):e71335.
Authors: He T, Betensky RA, Osorio RS, Swinnerton K, Zheng C, Jacobs T, Vedvyas A, Marsh K, Chodosh J, Hwang UY, Sifnugel N, Bubu OM, Wisniewski T, Brophy M, Do NV, Fillmore NR, Ramos-Cejudo J
PubMed: 41930609
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The Glymphatic System and Meningeal Lymphatics: Current Understandings and Future Perspectives.

MedComm (2020). 2026 Apr;7(4):e70691. Epub 2026 Mar 28
Authors: Sun H, Fan H, Zhou Y, Zhu H, Chen Y, Zhang R, Wang K, Pan Y, Zhang A
PubMed: 41930354
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Alzheimer's Disease in Africa: A Scoping Review Protocol.

Health Sci Rep. 2026 Apr;9(4):e72229. Epub 2026 Apr 1
Authors: Nuamah JA, Avorgbedor FK, Dadson SS, Adu Asamoah E, Benson PY, Kukuia KK, Kanmounye US
PubMed: 41929988
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Deletion of SPI1 in microglia exacerbates amyloid pathology by impairing microglial response in Alzheimer's disease models.

Neuron. 2026 Apr 1; Epub 2026 Apr 1
Authors: Kim B, Tate MD, Karahan H, Wijeratne HR, Sharify AD, Wang SS, Kim JR, Al-Amin MM, Hartigan K, Chung S, Dabin LC, Acri DJ, Doud EH, John SK, Mosley AL, Kim J
PubMed: 41928507
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Efficacy, safety and predictors of response to electroconvulsive therapy in Lewy body disease.

Parkinsonism Relat Disord. 2026 Apr 1;146:108301. Epub 2026 Apr 1
Authors: Kobayashi M, Nishio Y, Satake Y, Kanemoto H, Ishida T, Kigawa Y, Hatakeyama S, Utsumi K, Ikeda M
PubMed: 41935401
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Generation of three hiPSC clones from a frontotemporal dementia (FTD) patient with a heterozygous MAPT mutation p.K298_H299insQ (c.896_897insACA).

Stem Cell Res. 2026 Apr 1;93:103980. Epub 2026 Apr 1
Authors: Hirose T, Ishikawa KI, Li Y, Oyama G, Hatano T, Hattori N, Akamatsu W
PubMed: 41934872
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DAPK1-Mediated Parkin Inactivation Enhances Neurotoxicity via MITOL-Dependent Degradation.

J Cell Mol Med. 2026 Apr;30(7):e71132.
Authors: Park CH, Shin D, Chung KC
PubMed: 41943176
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The relationship between alcohol use disorder, measures of cognitive decline, and Alzheimer disease biomarkers in middle aged and older adults.

Alcohol Clin Exp Res (Hoboken). 2026 Apr;50(4):e70278.
Authors: Hayibor LA, Anokhin A, Fisher SL, Goate A, Foroud TM, Schindler SE, Bierut LJ, Hartz SM
PubMed: 41941099
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L-Leucine Upregulates Lysosomal Biogenesis and Autophagy to Lower Plaques in 5XFAD Mouse Model of Alzheimer's Disease.

J Neurochem. 2026 Apr;170(4):e70432.
Authors: Paidi RK, Gorai S, Mondal S, Pahan K
PubMed: 41940752
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Older Adults, Anti-Amyloid Therapy, and Frailty: What Oncology Can Teach Us.

Eur J Neurol. 2026 Apr;33(4):e70567.
Authors: Borda MG, O'Hara-Veintimilla K, Aarsland D
PubMed: 41937403
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Don't rush use of lymphatic surgery in Alzheimer's disease.

Nature. 2026 Apr;652(8109):534.
Authors: Zhang J, Liu Z
PubMed: 41946988
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Congming decoction alleviates Alzheimer's Disease induced by Aβ25-35 in rats via the microbiota-metabolism-inflammation axis, demonstrating its formulation advantages.

Phytomedicine. 2026 Apr 1;155:158139. Epub 2026 Apr 1
Authors: Tang S, Peng Y, Li Y, Li Y, Sun H, Piao S, Liu Z, Wu Y, Hou Z, Liu Z, Liu S, Wang R
PubMed: 41946054
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Digital and Analogical Cognitive Stimulation in Older Adults with Alzheimer's Disease: A Multicenter Randomized Controlled Trial Study Protocol.

Acta Med Port. 2026 Apr 1;39(4):281-286. Epub 2026 Apr 1
Authors: Justo-Henriques SI, Padeiro M, Silva RC, Macedo J, Borges-Machado F, São João RM, Ribeiro O
PubMed: 41945905
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FDA-Approved Drugs to Treat Dementia.

J Psychosoc Nurs Ment Health Serv. 2026 Apr;64(4):5-6. Epub 2026 Apr 1
Authors:
PubMed: 41944823
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Midbrain Energy Homeostasis Biomarker for Differential Diagnosis of Early-Stage Parkinson Disease: A 1H and 31P MRI Study.

Radiology. 2026 Apr;319(1):e251533.
Authors: Yu Q, Zhang Y, Huang P, Li Y, Liu P, Jin Z, Wang X, Zhang B, Weng J, Wu P, Haacke EM, Wiegers EC, Wijnen JP, Klomp DW, Haller S, Chen S, Yan F, He N
PubMed: 41944724
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Decoupling Alzheimer Disease Pathologic Abnormalities at PET with Improved Clinical Relevance by Interpretable Adversarial Decomposition Learning.

Radiology. 2026 Apr;319(1):e252321.
Authors: Tang C, Sun X, Tang A, Ruan W, Liu F, Fang H, Gai Y, Liang Z, Su Y, Wang X, Lan X, Alzheimer’s Disease Neuroimaging Initiative, Australian Imaging Biomarkers and Lifestyle Flagship Study of Aging Group
PubMed: 41944723
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Breakpoints in Alzheimer's disease biomarkers and cognition across the aging spectrum: The Mayo Clinic Study of Aging.

Alzheimers Dement. 2026 Apr;22(4):e71227.
Authors: Hu M, Knopman DS, Therneau T, Fought AJ, Hofrenning E, Lowe VJ, Petersen RC, Algeciras-Schimnich A, Jack CR Jr, Stricker NH, Mielke MM, Vemuri P, Graff-Radford J
PubMed: 41944335
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Impact of early locus coeruleus lesions in the TgF344 Alzheimer's disease rat model.

Alzheimers Dement. 2026 Apr;22(4):e71334.
Authors: Marriott AE, Schroeder JP, Korukonda A, Pate BS, McCann KE, Weinshenker D, Kelberman MA
PubMed: 41943538
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Longitudinal blood pressure trajectories and tau-lipid biomarkers associated with dementia in hypertensive adults: Results from the population-based CRHCP cohort.

Alzheimers Dement. 2026 Apr;22(4):e71346.
Authors: Zhong S, Guo X, Ouyang N, Zhao L, Li J, Liu F, Wang C, Xue W, Liang Z, Sun Y, Zhao M, Zhao C
PubMed: 41943496
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Glial pathology networks reveal early olfactory vulnerability in post mortem human Alzheimer's disease.

Alzheimers Dement. 2026 Apr;22(4):e71322.
Authors: Jung DH, Park E, Ju HC, Moon C, Jahanshahi A
PubMed: 41943492
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Prolonged morning wake transitions associated with amyloid beta burden: A cross-sectional pilot study.

Alzheimers Dement. 2026 Apr;22(4):e71123.
Authors: von Fingerhut G, Makino K, Osuka Y, Ito K, Kato T, Satake S, Shimada H
PubMed: 41943488
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Tracking tau and cellular responses in human iPSC-microglia: from uptake to seedable secretion, including in extracellular vesicles.

Alzheimers Dement. 2026 Apr;22(4):e71337.
Authors: Karabova MK, Del Ser-Badia A, Hedegaard A, Washer SJ, Baykam Z, O'Brien DP, Vendrell I, Hester SS, Fischer R, Johnson E, Melia CE, Matthews-Palmer TR, Matadeen R, Santambrogio A, Metrick MA 2nd, Vendruscolo M, Keeling S, Cheam KA, McEwan WA, Kosik KS, Day TA, James WS, Cowley SA
PubMed: 41943483
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Baseline characteristics of the SINgapore GERiatric Intervention Study to Reduce Cognitive Decline and Physical Frailty (SINGER) multidomain dementia prevention randomized controlled trial and insights from the recruitment process.

Alzheimers Dement. 2026 Apr;22(4):e71313.
Authors: Yap KH, Chen C, Chong EJ, Kandiah N, Kivipelto M, Lai MK, Maier AB, Matchar DB, Phua AK, Teo CK, Xu X, Zhou HJ, Chen CP
PubMed: 41943481
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A perspective: PLA2G4A as drug target for vascular inflammation in Alzheimer's disease.

Alzheimers Dement. 2026 Apr;22(4):e71320.
Authors: Kanwal A, Kerman BE, Wang S, Camey K, Li B, Flores-Aguilar L, Ali N, McIntire LB, Shu CA, Louie SG, Head E, Arvanitakis Z, Yassine HN
PubMed: 41950067
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Health system patterns of imaging and fluid biomarker testing in the era of anti-amyloid therapies.

Alzheimers Dement. 2026 Apr;22(4):e71343.
Authors: Robb WH, Kaur G, Huang S, Martinez F, Nguyen B, Shin CH, Yang M, Conyers CT, Grilli CB, Upjohn DP, Ortega VE, Hohman TJ, Keegan RM, Parent EE, Cogswell PM, Graff-Radford J, Johnson DR, Ramanan VK, Koran ME
PubMed: 41950049
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Correction to "Effectiveness, safety, and biomarker dynamics of lecanemab in Chinese Alzheimer's disease population: A multicenter real-world study".

Alzheimers Dement. 2026 Apr;22(4):e71347.
Authors:
PubMed: 41950014
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Expert consensus on communicating tau PET results to persons living with MCI or dementia: Findings from a modified Delphi study.

Alzheimers Dement. 2026 Apr;22(4):e71321.
Authors: Erickson C, O'Brien KS, Largent EA, Harkins K, Coykendall C, Kleid M, Clapp JT, Karlawish J
PubMed: 41950013
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Diagnostic performance of salivary markers of Alzheimer's disease: A systematic review.

Alzheimers Dement. 2026 Apr;22(4):e71248.
Authors: Borelli PV, Machado L, Carello-Collar G, Ferreira PC, Lourenço de Lima AM, Bellaver B, Pascoal TA, Benedet AL, Ashton NJ, Zimmer ER, Borelli WV
PubMed: 41949995
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Home-based sleep monitoring reveals associations between amyloid accumulation and sleep alterations in individuals with subjective and mild cognitive impairment.

Alzheimers Dement. 2026 Apr;22(4):e71326.
Authors: Buchal A, Dzialas V, Doering E, Giehl K, Bischof GN, Elmenhorst D, van Eimeren T, Drzezga A, Hoenig MC, T‐POT study group
PubMed: 41949989
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Mild cognitive impairment-to-Alzheimer's dementia progression risk: the contribution of the Interceptor project.

Alzheimers Dement. 2026 Apr;22(4):e71204.
Authors: Lombardo FL, Caraglia N, Lorenzini P, Vanacore N, Cappa SF, Cotelli M, Iodice F, Marra C, Miraglia F, Pappalettera C, Perani D, Quaranta D, Redolfi A, Spadin P, Tagliavini F, Vecchio F, Rossini PM, INTERCEPTOR Network
PubMed: 41949058
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Proteomic profiling of brain organoids and extracellular vesicles identifies early Alzheimer's disease biomarkers and drug response heterogeneity.

Alzheimers Dement. 2026 Apr;22(4):e71273.
Authors: Boyd RJ, Dong D, Sagar R, Iliuk A, Ahmed W, Androni X, Porsteinsson AP, Rosenberg PB, Lyketsos CG, Witwer KW, Mahairaki V
PubMed: 41949026
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Gene-Environment Interactions for Alzheimer's Disease Pathology in Cognitively Normal Adults: The CABLE Study.

Eur J Neurol. 2026 Apr;33(4):e70558.
Authors: Guo ZX, He XY, Ge YJ, Zhao B, Huang LY, Chen SD, Fu Y, Gao PY, Sheng ZH, Huang YM, Li QY, Tan L
PubMed: 41947717
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A network signature of Parkinson's disease.

Nat Neurosci. 2026 Apr;29(4):772.
Authors: Howells H
PubMed: 41957303
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From Mechanisms to Medicine: Astrocyte Dysfunction in Stress-Related Neuroinflammation and Alzheimer's Disease.

Eur J Neurosci. 2026 Apr;63(7):e70508.
Authors: Gupta KR, Thombre KR, Umekar MJ
PubMed: 41956895
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Four-Repeat Tauopathy With PSP-Like Features in Severe Intellectual Disability: Two Autopsy Cases.

Neuropathol Appl Neurobiol. 2026 Apr;52(2):e70075.
Authors: Hata Y, Kaneko H, Yoshida K, Tanaka R, Ichimata S, Nishida N
PubMed: 41956570
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RFWD2 Mitigates AD-Like Cognitive Impairments via the JNK-SGK1 Signaling Pathway in Mice.

CNS Neurosci Ther. 2026 Apr;32(4):e70860.
Authors: Ying M, Qi X, Wang A, Zhong G, Tong W, Yu D, Liu G, Guo Y
PubMed: 41954517
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Synaptic density imaging in behavioral variant frontotemporal dementia: A comparison of 1 8F-SynVesT-1 and 1 8F-FDG PET.

Alzheimers Dement. 2026 Apr;22(4):e71283.
Authors: Fesharaki-Zadeh A, Cayir S, Ibrahim W, Yang Y, Gallezot JD, Naganawa M, Wu Y, Toyonaga T, Sadabad FE, O'Dell R, Pittman B, Nabulsi N, Strittmatter S, Carson RE, Huang Y, van Dyck CH, Mecca AP, Matuskey D
PubMed: 41954197
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Fruit-Derived Citri Reticulatae Semen Extract Attenuates Alzheimer's Disease Neuroinflammation and Cognitive Impairment via Modulation of the PI3K/Akt/FoxO1 Pathway.

Mol Nutr Food Res. 2026 Apr;70(7):e70452.
Authors: Li S, Zhang X, Zhang P, Wang X, Yang Y, Qin D, Law BY, Pan Y, Tang Y
PubMed: 41954172
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Integrative genomic and functional analyses reveal NINL as a modulator of tau aggregation.

Alzheimers Dement. 2026 Apr;22(4):e71352.
Authors: Swift SK, Huang G, Cochran JN, D'Oliveira Albanus R, Minaya MA, Castruita PA, Zhang R, Miller KJ, Starr E, Galasso G, Marsh JA, Kao AW, Harari O, Yokoyama JS, Karch CM
PubMed: 41954097
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TOMM40 suppression promotes neuronal cholesterol imbalance and molecular and behavioral phenotypes of Alzheimer's disease.

Alzheimers Dement. 2026 Apr;22(4):e71306.
Authors: Yang NV, Wang S, Li B, Simms J, Dinh L, Huang A, Oei JH, Yassine HN, Krauss RM
PubMed: 41954048
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Widespread hnRNP K Mislocalisation Suggests Differential Neuronal Vulnerability in the Neurodegenerative and Ageing Human Brain.

Neuropathol Appl Neurobiol. 2026 Apr;52(2):e70072.
Authors: Jiang X, Toomey CE, Lashley T, Gatt A
PubMed: 41952419
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Multimodal Radiomics of Precisely Segmented Hippocampal Subfields: Iron Deposition and Structural Biomarkers for Early Diagnosis of Alzheimer's Disease.

Neuroimage. 2026 Mar 31;:121900. Epub 2026 Mar 31
Authors: Li D, He J, Liu B, Zhu L, Yang Y, Peng Y, Nie L, Wang R
PubMed: 41933850
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Individual gray-white matter functional connection predicts tau spread and cognitive decline in Alzheimer's disease.

Neuroimage. 2026 Mar 31;332:121904. Epub 2026 Mar 31
Authors: Wang L, Gao Y, Lu J, Jiang Q, Wang H, Dong F, Zhao Q, Guan Y, Qi X, Zuo C, Yu J, Jiang J
PubMed: 41933844
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Free sugar intake and dementia risk: a Swedish cohort study on dietary sources and dementia subtypes.

J Nutr. 2026 Mar 31;:101518. Epub 2026 Mar 31
Authors: Zhang N, Andresen J, Janzi S, Glans I, Samuelsson J, Nägga K, Borné Y, Palmqvist S, Hansson O, Sonestedt E
PubMed: 41933838
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Engineered microglial membrane-coated polydopamine-based nanomedicine for precise treatment of Alzheimer's disease.

J Control Release. 2026 Mar 31;:114896. Epub 2026 Mar 31
Authors: Huang Q, Lv Y, Ye X, Xia X, Chen Y, Wang X, Tong F, Yang W, Bozorov K, Shevtsov M, Li H, Gao H, Ye B
PubMed: 41933799
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Differential profiles of motor dysfunction in amnestic versus non-amnestic mild cognitive impairment - The Vietnam Era Twin Study of Aging.

Neuroscience. 2026 Mar 31; Epub 2026 Mar 31
Authors: Koppelmans V, Tasdizen T, Elman JA, Franz CE, Kremen WS
PubMed: 41933718
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APOE genotype and astrocyte activity collectively influence AD biomarkers and Aβ burden.

Brain Res. 2026 Mar 31;1883:150283. Epub 2026 Mar 31
Authors: Chen W, Su F, Kong H, Wang Y, Yi C, Zheng Y, Fang Y, Shi X, Lin Y, Zhou J, Zhang X, Pei Z
PubMed: 41933683
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Spatial lipidomics identifies α-synuclein-induced lipid changes in an AAV-induced Parkinsonian mouse model.

Neurobiol Dis. 2026 Mar 31;223:107372. Epub 2026 Mar 31
Authors: He Y, Kaya I, Zhang X, Nilsson A, Cao L, Andren PE, Svenningsson P
PubMed: 41933666
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The Role of Non-Coding RNA-Mediated Autophagy in Alzheimer's Disease.

Brain Res Bull. 2026 Mar 31;:111860. Epub 2026 Mar 31
Authors: Wang Y, Bao G, Li H, Li X, Lv L
PubMed: 41933660
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Inhibition of ESCRT-III activates alternative pathways for protein degradation and secretion.

Neurochem Int. 2026 Mar 31;196:106153. Epub 2026 Mar 31
Authors: Fujiwara M, Sakai R, Takahashi M, Matsumoto G, Hashimoto T, Kabuta T
PubMed: 41933658
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Stability and Dynamics of the N‑Terminal Domain of TDP-43 and the Effect of Point Mutations.

ACS Omega. 2026 Mar 31;11(12):19124-19133. Epub 2026 Mar 18
Authors: Pınar O, Jana AK, Yaşar F
PubMed: 41939353
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[18F]-Flortaucipir PET/MRI Supports a 4R Tauopathy Phenotype in Corticobasal Degeneration.

Clin Nucl Med. 2026 Mar 31; Epub 2026 Mar 31
Authors: Chen M, Franceschi AM
PubMed: 41949407
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Dysfunctional microglia-targeted nanoscavenger synergistically accelerates Aβ clearance and inhibits inflammatory cascade.

Biomaterials. 2026 Mar 27;333:124163. Epub 2026 Mar 27
Authors: Sun X, Xi Y, Chen Y, Zhou J, Ni J, Ding Y, Zhang H
PubMed: 41931967
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Synergistic Anti-dementia Effects of Symplocos racemosa Nanoemulsion: Isolation, Molecular Docking, and In Vivo Evaluation.

Curr Neurovasc Res. 2026 Mar 27; Epub 2026 Mar 27
Authors: Singh A, Mazumder A, Das S, Kumar R, Kanda A
PubMed: 41930762
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Glymphatic System Dysfunction in Alzheimer's Disease: Insights into its Mechanisms, Diagnostic Imaging, and Therapeutic Perspectives: A Systematic Review.

Curr Alzheimer Res. 2026 Mar 27; Epub 2026 Mar 27
Authors: Mehrabadi S, Samarghandian S
PubMed: 41928632
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Nanocarriers in Alzheimer's Therapy: A Comprehensive Review on Nanoparticulate Drug Delivery Systems.

Curr Neurovasc Res. 2026 Mar 26; Epub 2026 Mar 26
Authors: Parashar AK, Saraogi GK, Sethi VA, Ahmad Yasin HK
PubMed: 41930767
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Mendelian Randomization Analysis of Different Cathepsin Isoforms Associated with Neurodegenerative Diseases.

Curr Neurovasc Res. 2026 Mar 26; Epub 2026 Mar 26
Authors: Yang F, Shi X, Wang Y, Yin Y, Wu H, Ma K
PubMed: 41930763
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Targeting Blood-Brain Barrier Damage with Nanotechnology in the Fight Against Neurodegenerative Diseases.

CNS Neurol Disord Drug Targets. 2026 Mar 26; Epub 2026 Mar 26
Authors: Rajeshwar V, Ronald Darwin C, Ilango K, Iswariya VT, Begum SS, Mohan VK
PubMed: 41930585
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NEAT1 as a Diagnostic Biomarker and Therapeutic Target for Alzheimer's Disease: A Comprehensive Review.

CNS Neurol Disord Drug Targets. 2026 Mar 26; Epub 2026 Mar 26
Authors: Zamanian MY, Belaia OF, Gardanova ZR
PubMed: 41930583
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Digital Technology in Cognitive Decline: Bibliometric and Visualization Study.

Curr Alzheimer Res. 2026 Mar 26; Epub 2026 Mar 26
Authors: Huang Y, Zhu X, Yang S, Zhang Y, Tan Z, Han S
PubMed: 41928631
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Application of Chinese Pre-trained Language Models in Early Detection of Cognitive Impairment: A Comparative Study Based on Spoken Text.

Curr Alzheimer Res. 2026 Mar 26; Epub 2026 Mar 26
Authors: Chen X, Chen J, Mu Y, Pan X, Feng S
PubMed: 41928630
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Neuroprotective Mechanisms of Erucin: Therapeutic Pathways in Neurodegenerative Disorders.

Curr Neuropharmacol. 2026 Mar 25; Epub 2026 Mar 25
Authors: Patel S, Sood R, Shrivastava S, Jeengar MK
PubMed: 41930760
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AI-Driven Biomarker Discovery in Motor-Related Neurodegenerative Diseases.

CNS Neurol Disord Drug Targets. 2026 Mar 25; Epub 2026 Mar 25
Authors: Pavithra N, Begum RF, Ashwini ST, Nirenjen S, Singh A, Manisha M, Sridevi S, Singh SA
PubMed: 41930586
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Biotechnological Perspectives on GSK-3β and Hyperprolactinemia: Implications for the Progression of Alzheimer's Disease.

CNS Neurol Disord Drug Targets. 2026 Mar 25; Epub 2026 Mar 25
Authors: Venkatesan SJ, Devraj M, Virupakshappa MG, Dubey S, Kadiri SK, Tiwari P
PubMed: 41930581
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Modified Kai-Xin-San ameliorates cognitive impairment in Alzheimer's disease model mice by regulating neuroinflammation and synaptic dysfunction.

Phytomedicine. 2026 Mar 24;155:158102. Epub 2026 Mar 24
Authors: Liu XY, Wang K, Zhong JJ, Lin CL, Zhu JR, Wang PP, Guo R, Shao SS, Lim HS, Siow KL, Shan Kek R, Ng YH, Chen M, Han RC, Yao H, Zheng GQ, Wen L
PubMed: 41931996
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A microbiome quantitative trait locus in SLC39A8 modulates disease severity in synucleinopathy-induced models of Parkinson's disease.

Hum Mol Genet. 2026 Mar 23;35(6)
Authors: Yang JC, Situ J, Troutman R, Zhu R, Black M, Buri H, Gutta A, Tian F, Kang A, Aja E, Zeng A, Lai RW, Tan J, Liang F, Brahim C, Murphy G, Ahdoot A, Peng C, Jacobs JP
PubMed: 41955304
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Integration of Single-cell RNA Sequencing and Mendelian Randomization Analysis for Identifying Potential Immune Therapeutic Targets in Amyotrophic Lateral Sclerosis.

Biomed Environ Sci. 2026 Mar 20;39(3):327-341.
Authors: Pang XY, Wang HF, Bai JM, Huang XS
PubMed: 41944768
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Frontal variant Alzheimer's disease presenting as late-onset psychiatric illness: A case series highlighting diagnostic challenges on inpatient psychiatric units.

J Natl Med Assoc. 2026 Mar 19; Epub 2026 Mar 19
Authors: Patel S, Reisch A, Narapareddy BR
PubMed: 41933986
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Hydrogel-forming Microneedles: A Next-generation Approach for Enhanced Dermal Drug Delivery in Alzheimer's and Neurological Disorders.

Cent Nerv Syst Agents Med Chem. 2026 Mar 19; Epub 2026 Mar 19
Authors: Natarajan J, Ranganathan S
PubMed: 41941283
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A Systematic Review on Isoquinoline Derivatives as Emerging Multi-target Agents in Alzheimer's and Parkinson's Disorder Therapy.

Cent Nerv Syst Agents Med Chem. 2026 Mar 19; Epub 2026 Mar 19
Authors: Subramanian I, Surajambika RR, Sekar D, Natarajan R, Nagarajan NC
PubMed: 41941281
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The Role of Presynaptic Cytomatrix Protein Bassoon (BSN) in Tau Pathology and Propagation.

CNS Neurol Disord Drug Targets. 2026 Mar 18; Epub 2026 Mar 18
Authors: Oo WJ, Sia WT, Lee JY, Chen CH, Chang WL, Chye SM
PubMed: 41941234
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Pathogenic Protein Post-Translational Modifications in Alzheimer's Disease: Mechanisms and Therapeutic Strategies.

CNS Neurol Disord Drug Targets. 2026 Mar 18; Epub 2026 Mar 18
Authors: Vijayalakshmi A, Prabhakar V
PubMed: 41944134
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The Role of Glycans and Glycosyltransferases Involved in N-glycan Branching in Cancer, COPD, Alzheimer's Disease, and Redox Regulation.

J Vis Exp. 2026 Mar 17;(229)
Authors: Taniguchi N, Ohkawa Y, Nakano M, Gu J, Takahashi M
PubMed: 41941495
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Effects of Hesperetin Early Intervention on Brain Neurons and Microglia in APPswe/PS1dE9 Mice.

CNS Neurol Disord Drug Targets. 2026 Mar 16; Epub 2026 Mar 16
Authors: Wang N, Wen H, Sun Y, Xu W, Shen X, Wang R
PubMed: 41941239
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Genetic predisposition to hand grip strength predicts cognitive decline.

Neurobiol Aging. 2026 Mar 16;164:28-38. Epub 2026 Mar 16
Authors: Bercovitch R, Tio ES, Wickramatunga R, Misztal M, Gicas K, De Jager PL, Schneider JA, Buchman AS, Bennett DA, Rajji T, Kennedy JL, Felsky D
PubMed: 41955736
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Association of Cardiovascular-Kidney-Metabolic Health With Structural Brain Imaging and the Risk of Specific-Cause Dementia: A Cohort Study.

Am J Geriatr Psychiatry. 2026 Mar 10; Epub 2026 Mar 10
Authors: Zhang H, Liu X, Lyu D, Hou T, Xue F, Du Y
PubMed: 41936465
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Emerging Therapies and Research in Alzheimer's Disease: A Critical Review.

Cent Nerv Syst Agents Med Chem. 2026 Mar 10; Epub 2026 Mar 10
Authors: Agrawal MM, Mittal P
PubMed: 41941282
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DCPS modulates TDP-43-linked neurodegeneration through P-body-mediated RNA decay.

Neuron. 2026 Mar 9; Epub 2026 Mar 9
Authors: Ye Y, Zhang Z, Xiao Y, Zhu C, Wright N, Asbury J, Huang Y, Wang W, Gomez-Isaza L, Troncoso JC, He C, Sun S
PubMed: 41943580
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Inflammatory Signatures and Biomarkers: The Renal-Vesical Axis in Alzheimer Progression.

Int Neurourol J. 2026 Mar;30(1):3-10. Epub 2026 Mar 31
Authors: Kim Y, Jung J, Cirunduzi AC, Yoon S, Bang S, Yang SH
PubMed: 41942332
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The Crossroads of Neurodegeneration: Exploring the Overlap Between Alzheimer's Disease and Depression.

Cureus. 2026 Mar;18(3):e104771. Epub 2026 Mar 6
Authors: Bhatia P, Rosales JP, Patel P, Brini G, Singh J, Patel R, Petroski J, Brisman B, Sandhu M, Santacroce N, Singh A, Kaur G
PubMed: 41943747
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Short-Latency Afferent Inhibition and Cognitive Function in Older Adults With Mild Cognitive Impairment: A Pilot Study.

Brain Neurorehabil. 2026 Mar;19(1):e2. Epub 2026 Mar 12
Authors: Kim S, Jeong T, Park S, Kim DY
PubMed: 41953801
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Blood level of β-amyloid, Tau, and p-Tau in mild cognitive impairment and Alzheimer disease: A follow up study.

Indian J Med Res. 2026 Feb;163(2):166-173.
Authors: Pradhan R, Kumari S, Singh AK, Rao AR, Yadav Y, Upadhyay AD, Mehta PK, Dey AB, Dey S
PubMed: 41949144
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PPARG as a central regulator of ferroptosis in Alzheimer's disease: integrated transcriptomic, single-cell, and experimental evidence.

Front Aging Neurosci. 2026;18:1759279. Epub 2026 Mar 18
Authors: Tang L, Wu N, Xu H, Mo Y
PubMed: 41930369
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Glial lactate metabolism and transport in Alzheimer's disease.

Front Aging Neurosci. 2026;18:1731089. Epub 2026 Mar 18
Authors: Wang Y, Feng B, Hong R, Qiu D, Zhao J, Zhao L
PubMed: 41930368
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Unraveling the impact of common medications on biomarker patterns in Alzheimer's disease and mild cognitive impairment.

J Alzheimers Dis Rep. 2026;10:25424823251387281. Epub 2026 Jan 30
Authors: Paez K, Kopachik C, Yilmaz A, Vishweswaraiah S, Ashrafi N, Saiyed N, Monacelli N, Kerseviciute I, Gordevicius J, Ruff S, Pai A, Khaled I, Maddens ME, Graham SF
PubMed: 41929983
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Identification of novel serum biomarkers for Alzheimer's disease screened by phage display library of random peptides.

J Alzheimers Dis Rep. 2026;10:25424823261432141. Epub 2026 Mar 10
Authors: Gao D, Han Z, Ai X, Wang F, Lai D, Gao C, Zhang Z, Tao S, Shang J, Zhang J
PubMed: 41929982
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Estimates of current capacity for diagnosing and implementation of new treatment Alzheimer's disease in Slovenia.

J Alzheimers Dis Rep. 2026;10:25424823261424524. Epub 2026 Mar 19
Authors: Zupanic E, Stegnar G, Rakuša M, Rus Prelog P, Švab I, Gregoric Kramberger M
PubMed: 41929981
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A novel PSEN2 missense variant in a Japanese woman with hereditary Alzheimer's disease.

J Alzheimers Dis Rep. 2026;10:25424823261424532. Epub 2026 Feb 11
Authors: Kasuga K, Yuzawa C, Nakamura K, Shimizu Y, Hara N, Ikeuchi T, Sekijima Y
PubMed: 41929977
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Towards practical application of deep learning in diagnosis of Alzheimer's disease.

J Alzheimers Dis Rep. 2026;10:25424823261415808. Epub 2026 Jan 19
Authors: Parmar H, Walden E, Alzheimer's Disease Neuroimaging Initiative *
PubMed: 41929976
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TREM2 in Alzheimer's disease: A global bibliometric analysis of research evolution and therapeutic implications.

J Alzheimers Dis Rep. 2026;10:25424823251411528. Epub 2026 Jan 6
Authors: Cui L, Yue Z, Sun C, Shao K
PubMed: 41929975
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Characteristics of publicly available digital dementia risk screening tools: A scoping review.

J Alzheimers Dis Rep. 2026;10:25424823261433534. Epub 2026 Mar 30
Authors: Rwodzi Z, Mellow ML, Wu DP, Laver K, Dumuid D, Smith AE
PubMed: 41929974
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Diagnostic association of ante-mortem biomarkers with cerebral amyloid angiopathy in a cohort with high Alzheimer's disease comorbidity.

J Alzheimers Dis Rep. 2026;10:25424823261433955. Epub 2026 Mar 13
Authors: Hou K, Lu H, Zhang R, Wang Y, Xu G, Long F, Lu J, Xing D, Huang L, Sun Y, Alzheimer's Disease Neuroimaging Initiative
PubMed: 41929973
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Exploring shared molecular pathways and gene signatures in type 2 diabetes mellitus and Alzheimer's disease in a Pakistani cohort.

J Alzheimers Dis Rep. 2026;10:25424823251403462. Epub 2026 Mar 31
Authors: Noreen Z, Mondal T, Johnson J, Sahota J, Loffredo CA, Nunlee-Bland G, Korba B, Bhatti A, Chandra V, Ghosh S
PubMed: 41929972
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Comprehensive and stratified meta-analysis of diffusion tensor image analysis along the perivascular space in Alzheimer's disease: Linking glymphatic dysfunction with cognitive decline and amyloid pathology.

J Alzheimers Dis Rep. 2026;10:25424823261424508. Epub 2026 Feb 13
Authors: Zafari R, Taherkhani T, Kamroo A, Nabizadeh F
PubMed: 41929971
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N-Glycosylation and Alzheimer's disease: A 2001-2025 global bibliometric landscape revealing emerging diagnostic trends.

J Alzheimers Dis Rep. 2026;10:25424823251412909. Epub 2026 Jan 8
Authors: Shi G, Ju F, Dong Q, Fang Y
PubMed: 41929970
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The Cheung Glutamatergic Regimen as a candidate for primary and secondary prevention of Alzheimer's disease onset.

J Alzheimers Dis Rep. 2026;10:25424823261433953. Epub 2026 Mar 13
Authors: Cheung N
PubMed: 41929967
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Social determinants of health, genetic biomarkers, and cognitive function in Chinese older adults with subjective cognitive decline and mild cognitive impairment: A cross-sectional analysis.

J Alzheimers Dis Rep. 2026;10:25424823251409405. Epub 2026 Jan 13
Authors: Shi CX, Li JH, Liu J, Zhou QM, Yang X, Cheng YQ, Xia N, Li HB, Meng FF, Wang T, Zhu Y
PubMed: 41929966
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TARDBP gene mutation in a Chinese family with frontotemporal dementia: A case report and literature review.

J Alzheimers Dis Rep. 2026;10:25424823251412416. Epub 2026 Jan 12
Authors: Zhao X, Wu L, Li P
PubMed: 41929964
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A novel PSEN1 (p.Gln223Leu) variant associated with spastic paraparesis and early-onset Alzheimer's disease.

J Alzheimers Dis Rep. 2026;10:25424823261419068. Epub 2026 Jan 28
Authors: Lee HJ, Im H, Yoon B, Shim Y, Won D, Lee JH
PubMed: 41929960
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Challenges in community-based recruitment of Alzheimer's disease cases: Experience of the monitoring drug efficacy through multi-omics research initiative in Alzheimer's disease (MEMORI-AD) study.

J Alzheimers Dis Rep. 2026;10:25424823261431318. Epub 2026 Mar 9
Authors: Climacosa FM, Ornos ED, Diwa ER, Guantia MG, Qureshi AP, Gapaz NC, Dacasin AB, Asis JL, Carampel AC, Dela Cruz AM, Gordovez FJ, Reyes JC, Tabios IK, Manalo RV, Cruz JM, Anlacan VM
PubMed: 41929959
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Applications and implicit assumptions in dementia risk scores: A scoping review of the LIBRA score.

J Alzheimers Dis Rep. 2026;10:25424823261416457. Epub 2026 Jan 22
Authors: Kant WM, de Swart WK, Smit JM, Loog M, Krijthe JH
PubMed: 41929958
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Qualitative insights into participant and care partner perspectives on research-based Alzheimer's disease biomarker testing and disclosure.

J Alzheimers Dis Rep. 2026;10:25424823261429997. Epub 2026 Mar 13
Authors: Rahman-Filipiak A, Lesniak M, Burgei A, Sadaghiyani S, Roberts JS, Lichtenberg PA, Iordan A, Mozersky J, Hampstead BM
PubMed: 41929956
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P-tau217 and %p-tau217 exhibited superior diagnostic accuracy over other blood biomarkers in the initial assessment of individuals being diagnosed with mild cognitive impairment and Alzheimer's disease dementia.

J Alzheimers Dis Rep. 2026;10:25424823261439687. Epub 2026 Mar 31
Authors: Qiu Q, Qian W, Zhao W, Xie H, Cao L, Ye L, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 41929955
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Microbiome alterations in Alzheimer's disease: A systematic review of current evidence and global perspectives.

J Alzheimers Dis Rep. 2026;10:25424823261436287. Epub 2026 Mar 25
Authors: Oso TA, Okesanya OJ, Adebayo UO, Obadeyi KB, Ayelaagbe OB, Talabi OA, Adewole PD, Anorue CO, Ahmed MM, Talabi OT, Ogaya JB, Lucero-Prisno DE 3rd
PubMed: 41929953
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Network meta-analysis of the efficacy of nine drugs for cognitive function in patients with Alzheimer's disease.

J Alzheimers Dis Rep. 2026;10:25424823261422205. Epub 2026 Feb 6
Authors: Huang S, Guo Y
PubMed: 41929952
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Exploring BSCL2 and associated genes in Alzheimer's disease by integrative analysis of bioinformatics, sn-RNAseq and machine learning approach.

J Alzheimers Dis Rep. 2026;10:25424823261423079. Epub 2026 Feb 11
Authors: An X, Wang Y, Cao M, Yi Z, Zeng X, Yu W, Ren Z
PubMed: 41929951
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The causal association between the new gut microbiota and Alzheimer's disease: A Mendelian randomization study.

J Alzheimers Dis Rep. 2026;10:25424823261422629. Epub 2026 Feb 6
Authors: Lin F, Yang X, Xie X, Qiu L, Zheng C, Zheng X, Li Z, Nie B
PubMed: 41929950
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From routine periodontal therapy to Alzheimer's disease early detection: A scoping review.

J Alzheimers Dis Rep. 2026;10:25424823261421629. Epub 2026 Feb 4
Authors: Zhang Q, Almanie L, Ouyang Y, Cheng Z, Zhang H
PubMed: 41929949
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Distinct brain volume changes associated with the head-turning sign and Neucop-Q response patterns in Alzheimer's disease.

J Alzheimers Dis Rep. 2026;10:25424823261437682. Epub 2026 Mar 25
Authors: Watanabe M, Bun S, Shimizu A, Iwabuchi Y, Mori S, Jinzaki M, Mimura M, Ito D
PubMed: 41929948
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Large-scale APP duplication in early-onset Alzheimer's disease without cerebral amyloid angiopathy: A case report.

J Alzheimers Dis Rep. 2026;10:25424823251412896. Epub 2026 Jan 6
Authors: Shimohama S, Azami S, Oyama M, Takizawa T, Kubota M, Suzuki H, Yamada M, Nakahara J, Ito D
PubMed: 41929947
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Molecular sabotage of hippocampal synaptic plasticity by amyloid-β in Alzheimer's disease: A narrative review.

J Alzheimers Dis Rep. 2026;10:25424823261415807. Epub 2026 Feb 6
Authors: Behroozi Z, Askarpour H, Baghcheghi Y
PubMed: 41929946
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Identification of potential short-chain fatty acid biomarkers in Alzheimer's disease through bioinformatics analysis.

J Alzheimers Dis Rep. 2026;10:25424823261424808. Epub 2026 Feb 19
Authors: Yang Y, Meng Y, Li M, Xu Z, Wu H, Zhang Q, Zhang S, Kong F, Wang Z, Li X, Zhu Y
PubMed: 41929945
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Unraveling the molecular links: Alzheimer's disease-induced mechanisms of memory impairment: A narrative review.

J Alzheimers Dis Rep. 2026;10:25424823251412327. Epub 2026 Jan 6
Authors: Baghcheghi Y, Razazpour F, Mohammadi M, Mashayekhi H, Hedayati-Moghadam M
PubMed: 41929944
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Prediction of clinical and language changes after a single session of repetitive transcranial magnetic stimulation in primary progressive aphasia: A machine learning approach.

J Alzheimers Dis Rep. 2026;10:25424823261420785. Epub 2026 Feb 4
Authors: Rubio CM, Fernández-Romero L, Balugo P, Fraile-Pereda A, Suárez-Coalla P, Cabrera-Martin MN, Yus-Fuertes M, Matias-Guiu JA, Ayala JL
PubMed: 41929943
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The diagnostic value of plasma phosphorylated tau 181 in Alzheimer's disease within the Chinese population: A systematic review and meta-analysis.

J Alzheimers Dis Rep. 2026;10:25424823261432112. Epub 2026 Mar 5
Authors: Yan K, Li H, He S, Jia X, Liu D, Chen J
PubMed: 41929942
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Associations between systemic inflammatory markers and cognitive decline in patients with early-stage Alzheimer's disease: a retrospective clinical study.

Front Neurol. 2026;17:1765287. Epub 2026 Mar 18
Authors: Liu Y, Li Y, Zheng P, Zhang B
PubMed: 41929599
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Repeated Administration of Social and Structural Determinants of Health (SSDOH) Questions in an Alzheimer's Disease Research Center: The Aging Brain Study (ABC) Life Experience Survey.

Sage Open Aging. 2026;12:30495334261430788. Epub 2026 Mar 31
Authors: Stites SD, Lee DS, Kuz C, Humphreys V, Streitz ML, Xie SX, Flatt J, Glover CM, Mechanic-Hamilton D
PubMed: 41928917
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Correction: Exploring emotion recognition in patients with mild cognitive impairment and Alzheimer's dementia undergoing a rehabilitation program emotion recognition in patients with dementia.

PLoS One. 2026;21(4):e0346658. Epub 2026 Apr 6
Authors: PLOS One Staff
PubMed: 41941399
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Emotional-cognitive integration in aging: the role of alexithymia in mild cognitive impairment.

Front Public Health. 2026;14:1737901. Epub 2026 Mar 19
Authors: Marselli G, Corbo I, Pecchinenda A, Forte G, Favieri F, Troisi G, Blasutto B, Casagrande M
PubMed: 41941323
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A computational framework to predict the spreading of Alzheimer's disease.

Eng Comput. 2026;42(2):78. Epub 2026 Apr 2
Authors: Vazquez-Palomo A, Betegón C, Weickenmeier J, Martínez-Pañeda E
PubMed: 41940407
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Platelets from early-stage Alzheimer patients show enhanced amyloid binding, an elevated open canalicular system and sex-specific differences in their activation profile.

Front Neurol. 2026;17:1759268. Epub 2026 Mar 19
Authors: Donner L, Christl J, Kujovic M, Supprian T, Elvers M
PubMed: 41940301
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Sex-dependent grey matter atrophy in Alzheimer's disease progression.

Brain Commun. 2026;8(2):fcag103. Epub 2026 Apr 3
Authors: Mukherjee C, Bajaj S, Adhikari BM, Dhamala M
PubMed: 41940185
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Therapeutic potential of exerkines in neurodegenerative and mental disorders: a narrative review.

Front Physiol. 2026;17:1793043. Epub 2026 Mar 19
Authors: Yang S, Sang HW, Kim S, Cho EJ, Choi Y, Kang DW, Jang YC, Park DH, Kwak HB, Yook JS
PubMed: 41940019
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A study on the correlation between APOE gene polymorphism, white matter hyperintensities, and neuropsychiatric symptom phenotypes in Alzheimer's disease.

Front Psychiatry. 2026;17:1795598. Epub 2026 Mar 20
Authors: Fan W, Wang Z, Wan S, Liu M, Han Y, Liu X, Xu L, Wang X, Zhang D, Cai Q
PubMed: 41938851
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Safety and Efficacy of Mesenchymal Stem Cell Therapy in Multiple System Atrophy: Systematic Review.

Biologics. 2026;20:593367. Epub 2026 Mar 31
Authors: Elimam N, Albarari SS, Shaalan Y, Elsheikh SM, Alzamari AA, Elmekkawi N, Mogahed R, Alghuweiri RH
PubMed: 41938822
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Identifying transcriptomic signatures that mediate the causal effect of genotype on Alzheimer's disease.

Front Neurosci. 2026;20:1716828. Epub 2026 Mar 11
Authors: Kaur S, Tyler AL, Durante GL, Cary GA, Carter GW, Mahoney JM
PubMed: 41938695
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Non-Coding DNA-Derived Mimotopes of Aβ₄₂ as Novel Candidates for Alzheimer's Peptide Vaccine Design.

Int J Med Sci. 2026;23(4):1320-1332. Epub 2026 Mar 4
Authors: Raj N, R SP, Ammar RB, Rajendran P, Chellappan BV
PubMed: 41938524
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Astrocytic K+ regulation during neurodegenerative diseases.

Front Aging Neurosci. 2026;18:1782460. Epub 2026 Mar 19
Authors: Samokhina E, Buskila Y
PubMed: 41938070
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Protein lactylation in Alzheimer's disease: bridging metabolism, pathology, and therapeutic opportunity.

Front Aging Neurosci. 2026;18:1790090. Epub 2026 Mar 20
Authors: Cao H, Liang J, Dong X, Xia Z, Luo X, Liu B
PubMed: 41938067
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Correction: A Physics Informed Neural Network (PINN) framework for fractional order modeling of Alzheimer's disease.

Front Neuroinform. 2026;20:1821637. Epub 2026 Mar 19
Authors: Mehmood A, Farman M, Afzal F, Nisar KS, Ahmed MA, Hafez M
PubMed: 41937809
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Natural Chiral Scaffolds in Alzheimer's Disease: Therapeutic Potential, Mechanism, and Clinical Aspects.

Biomed Res Int. 2026;2026(1):e5968529.
Authors: Singh A, Sahu SK, Sah AK
PubMed: 41944346
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White matter microstructure disruption associated with PET and cognitive impairment in Alzheimer's disease.

PLoS One. 2026;21(4):e0346661. Epub 2026 Apr 8
Authors: Gonzales M, Kang X, Cort C, Adamson MM, Chao SZ, Yoon BC, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 41950270
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Hyaluronic acid: emerging roles and biomaterial innovations in Alzheimer's and Parkinson's disease therapy.

Front Pharmacol. 2026;17:1772172. Epub 2026 Mar 23
Authors: Wang Y, Duan J, Zang L, Sun T, Lv H, Liu F, Ma X
PubMed: 41948730
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Enhancing Early Diagnosis: Multimodal AI Approaches for Neurodegenerative Diseases.

J Biotechnol Biomed. 2026;9(1):67-76. Epub 2026 Mar 10
Authors: Swamy A, Agrawal DK
PubMed: 41948713
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Nanoengineered phytochemicals overcome blood-brain barrier constraints in neurodegenerative disorders.

Front Neurol. 2026;17:1792829. Epub 2026 Mar 23
Authors: Naim A, Farooqui AM, Badruddeen, Khan MI, Akhtar J, Ahmad A, Ashique S, Islam A
PubMed: 41948610
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Time-dependent histological characterization of amyloid-β induced cholinergic and glial alterations and their modulation by dehydroepiandrosterone sulfate (DHEAS).

Front Endocrinol (Lausanne). 2026;17:1764298. Epub 2026 Mar 23
Authors: Sólyomvári C, Makkai G, Capelo-Carrasco N, Strac DS, Zelena D, Farkas S
PubMed: 41948553
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Gut Microbiota Diversity and Function in Adults With Type 2 Diabetes, Alzheimer's Disease, and Both Conditions.

Int J Microbiol. 2026;2026:5247744. Epub 2026 Apr 5
Authors: Rodríguez-Rosas AM, Baldenebro-Félix DL, Peréz-Villarreal JM, García-Mena J, Kawano-Soto CA, Camberos-Barraza J, Valdéz-Flores MA, Calderón-Zamora L, Angulo-Rojo CE, Magaña-Gómez JA, Guadrón-Llanos AM
PubMed: 41948549
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The influence of bilingualism on the assessment and treatment of an Italian-English speaker with the logopenic variant of PPA.

Alzheimers Dement (Amst). 2026;18(2):e70310. Epub 2026 Apr 2
Authors: Tomasoni R, Santi GC, Tagliente S, Griseta C, Aresta S, Benzini A, Santacesaria P, Palmirotta C, Mandelli ML, Grasso S, Battista P
PubMed: 41948541
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Incremental value of plasma biomarkers in predicting clinical decline among cognitively unimpaired older adults: Results from the A4 trial.

Alzheimers Dement (Amst). 2026;18(2):e70321. Epub 2026 Apr 3
Authors: Khorsand B, Ghanbarian E, Rabin LA, Sajjadi SA, Ezzati A
PubMed: 41948540
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Application of machine learning to blood-based biomarkers of Alzheimer's disease in Down syndrome.

Alzheimers Dement (Amst). 2026;18(2):e70325. Epub 2026 Apr 6
Authors: Luckett PH, Petersen M, O'Bryant S, Mapstone M, Christian BT, Handen B, Head E, Ances BM, Alzheimer's Biomarker Consortium‐Down Syndrome
PubMed: 41948539
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Potential correlation between chronic pain and amyloid beta in Alzheimer's disease.

Front Pain Res (Lausanne). 2026;7:1799860. Epub 2026 Mar 23
Authors: Liu Y, Wang XP
PubMed: 41948424
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Therapeutic potential of vagus nerve stimulation in neurodegenerative diseases: research progress and mechanisms.

Front Immunol. 2026;17:1811107. Epub 2026 Mar 23
Authors: Hu Q, Wang J, Cao R, Liu W, Wang L
PubMed: 41948329
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Systemic proteomic and organ aging signatures associated with plasma Aβ oligomerization in a Korean cohort: a cross-sectional study.

Front Aging Neurosci. 2026;18:1620991. Epub 2026 Mar 23
Authors: Oh H, Kim H, Kang H, Kwon D, French L, Park YH, Youn YC, An SS, Kim S, Kang S
PubMed: 41948065
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Interleukin-6, CD8+ T cells, and Alzheimer's disease: unraveling neuroimmune crosstalk via genetic and mechanistic insights.

Front Aging Neurosci. 2026;18:1767927. Epub 2026 Mar 23
Authors: Xu R, Song W, Zhang X
PubMed: 41948064
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Deep learning-based detection of cerebral microbleeds on 2D T2*-weighted GRE MRI: toward ARIA-H risk assessment in Alzheimer's treatment.

Front Aging Neurosci. 2026;18:1729422. Epub 2026 Mar 23
Authors: Yang SO, Ahn J, Jung YH, Jang H, Na DL, Kim H, Kim JP, Seo SW, Kwak K
PubMed: 41948063
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The effects of visual art therapy in older adults with mild cognitive impairment: a systematic review and meta-analysis.

Front Public Health. 2026;14:1765620. Epub 2026 Mar 23
Authors: Jiao Y, Zhang Y, Liu J
PubMed: 41948011
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Pre-analytical characterization of CNS-derived extracellular vesicles from human saliva: effect of room temperature and cellular origin.

Front Neurosci. 2026;20:1765229. Epub 2026 Mar 23
Authors: Licatini LM, Licatini LM, Haddadin FA, Conklin GC, Badhwar A, Sarsoza FM, Sukreet S, Winston CN
PubMed: 41947859
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The role of the MIND diet in prevention and treatment of Alzheimer's disease: A literature review.

Wiad Lek. 2026;79(2):390-398.
Authors: Krupa J, Malinowski M, Krasowski M, Kalinowska A, Pietras W, Kozieł A, Kurek Z, Jentkiewicz A, Obeid EH, Ulrych J
PubMed: 41955600
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Decentralizing dementia research to the US-Mexico border: the Rio Grande Valley AD-RCMAR as a model for translational equity.

Alzheimers Dement (N Y). 2026;12(2):e70238. Epub 2026 Apr 6
Authors: Maestre GE, Blangero J, Manusov EG, de Erausquin GA, Fernández F, Mejía-Arango S, Diego V, López-Alvarenga JC, Alaniz C, García N, Pirela RV, Tsin A, Mahaney MC
PubMed: 41953574
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EEG recordings during visuo-attentive task reduce sex bias in Alzheimer's disease diagnosis.

Alzheimers Dement (N Y). 2026;12(2):e70245. Epub 2026 Apr 6
Authors: Amato LG, Lassi M, Grippo A, Moschini V, Giacomucci G, Padiglioni S, Morinelli C, Nacmias B, Mazzoni A, Bessi V, Vergani AA
PubMed: 41953573
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Real-World Multimodal Day-Care Intervention for Mild Cognitive Impairment with Lewy Bodies: A Prospective 3-Year Comparative Cognitive Trajectory Study.

Dement Geriatr Cogn Dis Extra. 2026;16(1):11-20. Epub 2026 Feb 19
Authors: Nemoto M, Nemoto K, Ota M, Sasai H, Midorikawa H, Sekine A, Kitabatake A, Arai T
PubMed: 41953385
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Diagnostic Blood-Based Biomarkers of Amyloid-β and Tau Pathologies Prior to Alzheimer's Disease Diagnosis: a Rapid Umbrella Review.

SN Compr Clin Med. 2026;8(1):109. Epub 2026 Apr 6
Authors: Yousefzadeh N, Sharma O, Oliver A, O'Keefe H, Robertson EG, Harris B, Spiers GF, Craig D
PubMed: 41953170
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Herpes simplex virus 2 and dementia risk: a systematic review and meta-analysis.

Front Dement. 2026;5:1737068. Epub 2026 Mar 24
Authors: Hunt CJ, Zabriskie BN, Coulter EJ, McClellan MC, Templeton G, Erbstoesser R, MacLean S, Miller CH, Moss J, Carter C, Gale SD, Moore JD, Farrer TJ, Hedges DW
PubMed: 41953111
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Mitochondrial dysfunction in Alzheimer's disease and related sex differences.

Front Aging Neurosci. 2026;18:1761702. Epub 2026 Mar 24
Authors: Misrani A, Ngwa C, Liu F
PubMed: 41952873
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Neural and motor mechanisms of handwriting: from healthy aging to neurodegenerative disorders.

Front Aging Neurosci. 2026;18:1758541. Epub 2026 Mar 24
Authors: Burgio F, Pezzetta R, Gooijers J, Nordio S, Mantini D
PubMed: 41952872
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Intervention of ginseng-derived macromolecular drugs in Alzheimer's disease: exploring mechanisms and assessing potential.

Front Aging Neurosci. 2026;18:1752446. Epub 2026 Mar 24
Authors: Liu W, Bai Y, Qu W, Zhang X, Zhou S, Luo H, Zhu M, Li D, Fang X
PubMed: 41952870
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Cortical, subcortical, and cerebellar atrophy and cognition deficits in Metropolitan Mexico City teens and young adults exposed to fine particulate matter (PM2.5) - neurodegeneration is in progress.

Front Neurol. 2026;17:1772916. Epub 2026 Mar 24
Authors: Calderón-Garcidueñas L, Hernández-Luna J, Galaz-Montoya CI, Clouston SA, Aiello-Mora MV, Amaro de Gante J, Stommel EW, Torres-Jardón R, Nalbantoglu OU
PubMed: 41952858
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Flexible Multimodal Neuroimaging Fusion for Alzheimer's Disease Progression Prediction.

Appl Med Artif Intel (2025). 2026;16206:235-245. Epub 2026 Jan 2
Authors: Burns B, Xue Y, Scharre DW, Ning X
PubMed: 41952807
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MANF improves cognitive function and attenuates neuroinflammation in APP/PS1 transgenic mice through the TLR4/MYD88/NF-κB signaling pathway.

J Anesth Transl Med. 2025 Dec;4(4):241-254. Epub 2025 Dec 29
Authors: Tang Y, Zhuo E, Li P, Wang C, Hu X, Liu X, Xu G, Shen Q
PubMed: 41929929
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Diversity-sensitive brain clocks linked to biophysical mechanisms in aging and dementia.

Nat Ment Health. 2025 Oct;3(10):1214-1229. Epub 2025 Sep 18
Authors: Coronel-Oliveros C, Moguilner S, Hernandez H, Cruzat J, Baez S, Medel V, Cuadros J, Santamaria-Garcia H, Valdes-Sosa PA, Lopera F, Ochoa-Gómez JF, González-Hernández A, Bonilla-Santos J, Gonzalez-Montealegre RA, Aktürk T, Yıldırım E, Anghinah R, Legaz A, Fittipaldi S, Yener GG, Escudero J, Babiloni C, Lopez S, Whelan R, Fernández A, Huepe D, Di Caterina G, Soto-Añari M, Gonzalez-Gomez R, Herrera E, Abasolo D, Kilborn K, Rubido N, Clark R, Herzog R, Yerlikaya D, Güntekin B, Deco G, Prado P, Parra MA, Orio P, Tagliazucchi E, Lawlor B, Ibanez A
PubMed: 41929992
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