Alzforum - Papers of the Week: 12-18 Jun 2026

Differential A-to-I editing of SINE B2 RNAs unveils an epitranscriptome response to Aβ neurotoxicity.

Life Sci Alliance. 2026 Sep;9(9) Print 2026 Sep
Authors: Mitchell L, Saville L, Gollen B, Haight T, Roy R, Turner C, Cheng Y, Kovalchuk I, Mohajerani MH, Zovoilis A
PubMed: 42303461
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Expanding the Spectrum of BCAP31-Associated Diseases: Early-Onset Parkinson Disease.

Neurol Genet. 2026 Aug;12(4):e200404. Epub 2026 Jun 10
Authors: Ishiguro M, Funayama M, Park DH, Hatano T, Nakazato T, Luo Y, Osawa M, Li Y, Yoshino H, Hattori N, Kanai K
PubMed: 42312245
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The Prodromal Synucleinopathy Rating Scale: An Assessment in Patients With REM Sleep Behavior Disorder.

Neurology. 2026 Jul 14;107(1):e218176. Epub 2026 Jun 16
Authors: Boeve BF, Nie Y, Lu R, De La Cruz H, Avidan AY, Bliwise DL, Campbell MC, Criswell SR, Davis AA, Duff K, Elliott J, Ferman TJ, Fields JA, Forsberg LK, Gagnon JF, Howell M, Huddleston DE, Lim MM, Locke J, McCarter SJ, McLeland J, Miglis MG, Miyagawa T, Neilson LE, Nichols K, Pelletier A, Schenck CH, Louis EK, Sum-Ping O, Trotti LM, Videnovic A, Xiong C, Postuma R, Ju YS, NAPS Consortium
PubMed: 42302227
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Fecal Microbiota Transplantation in Parkinson Disease: A Systematic Review, Meta-Analysis, and Meta-Regression.

Neurology. 2026 Jul 14;107(1):e218175. Epub 2026 Jun 16
Authors: Pereira MA, Tudella GC, Klostermann AU, Ohannesian VA, Gonçalves OR, da Silva RO, Andrade Fernandes JV, Ahmed A, Alencar AB, de Morais ST, Almeida KJ
PubMed: 42302222
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Measuring the Prodrome Promise and Challenges of the Prodromal Synucleinopathy Rating Scale.

Neurology. 2026 Jul 14;107(1):e218260. Epub 2026 Jun 16
Authors: Hopfner F, Höglinger GU
PubMed: 42302221
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Clinical Impact and Prognostic Value of Alzheimer Disease Biomarkers in the Very Old.

Neurology. 2026 Jul 14;107(1):e218180. Epub 2026 Jun 17
Authors: Ceriello C, Torres OH, Rubio-Guerra S, García-Castro J, Selma-Gonzalez J, Sala I, Sánchez-Saudinós MB, Videla L, Vera-Campuzano E, Arranz J, Rodríguez-Baz Í, Maure-Blesa L, Dols-Icardo O, Valldeneu S, Barroeta I, Santos-Santos M, Carmona-Iragui M, Vaqué-Alcázar L, Alvarez-Sanchez E, Lorente O, Carreras M, Bejanin A, Belbin O, Lleó A, Fortea J, Alcolea D, Illán-Gala I
PubMed: 42308436
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Not Lost in Translation: Universality of Clinical-Pathobiologic Correlation in Alzheimer Disease.

Neurology. 2026 Jul 14;107(1):e218262. Epub 2026 Jun 18
Authors: Cash DM, Knopman DS
PubMed: 42314106
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Clinical Evaluation of the Revised Biological and Clinical Staging Criteria for Alzheimer Disease in China.

Neurology. 2026 Jul 14;107(1):e218184. Epub 2026 Jun 18
Authors: Wang ZY, Xin JW, Wang MY, Chen S, Chen K, Lu J, Huang YY, Zhang W, Huang W, Wang R, Xie F, Cheng W, Chen X, Zuo C, Cui M, Zhao Q, Yu JT
PubMed: 42314105
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Phase 2 Futility Trials in Alzheimer Disease and Mild Cognitive Impairment: A Cohort Analysis of the ADNI Data Set.

Neurology. 2026 Jul 14;107(1):e218227. Epub 2026 Jun 18
Authors: Ganesh A, Smith EE, Mostert J, Strijbis EM, Schoonheim MM, Xia C, Nadeau Y, Leavitt VM, Kalia LV, Engelborghs S, D'Haeseleer M, McPherson T, Cutter GR, Koch MW, for Alzheimer's Disease Neuroimaging Initiative (ADNI)
PubMed: 42314102
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Dextromethorphan/bupropion (Auvelity) for agitation in Alzheimer's dementia.

Med Lett Drugs Ther. 2026 Jun 22;68(1757):98-100.
Authors:
PubMed: 42295171
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CCN1/Cyr61 associates with β-amyloid levels in human cerebrospinal fluids.

iScience. 2026 Jun 19;29(6):116244. Epub 2026 Jun 5
Authors: Shinohara M, Momota H, Saito T, Takenobu C, Kasuga K, Gheni G, Kawai K, Morishima M, Saito Y, Shindo A, Yasuno F, Ikeuchi T, Fukumori A, Sato N
PubMed: 42305617
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Unveiling the pathogenesis and therapeutic strategies of Alzheimer's disease through cuproptosis.

Biometals. 2026 Jun 18; Epub 2026 Jun 18
Authors: Xu S, Mu J, Wang Z, Yang J, Tian D, Shi T, Lan J, He P, Hao Z, Fu Y, Xing L, Ye J, Wang J
PubMed: 42310191
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Impact of adjunctive quantitative analysis on visual interpretation of amyloid PET: a multiple tracer, multicentre study.

Eur Radiol. 2026 Jun 18; Epub 2026 Jun 18
Authors: Ha S, Choi B, Kwon SJ, Kang S, Son J, Jeong SY, Lee SW, Choe YS, Kim D, Hong CM
PubMed: 42310039
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Early oligodendrocyte dysfunction signature in Alzheimer's disease: Insights from DNA methylomics and transcriptomics.

Mol Psychiatry. 2026 Jun 18; Epub 2026 Jun 18
Authors: Fodder K, Smith HM, Yaman U, Piras IS, Murthy M, Hardy J, Lashley T, de Silva R, Salih DA, Bettencourt C
PubMed: 42315917
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Nanoparticles that target nonamyloid and nontau pathways in Alzheimer's disease.

Discov Nano. 2026 Jun 18;21(1)
Authors: Alavian F, Hajimohammadi A
PubMed: 42315809
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Association of Cathepsin Proteins with Alzheimer's Disease Risk: An Integrated Observational and Genetic Analysis.

Neuromolecular Med. 2026 Jun 18;28(1)
Authors: Zhang Q, Li Q, Ai Z, Li F, Wang Y, Zhou W
PubMed: 42315799
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FDG PET in Movement Disorders and Parkinsonian Syndromes.

PET Clin. 2026 Jun 18; Epub 2026 Jun 18
Authors: Minoshima S, van Eimeren T, Drzezga A
PubMed: 42315466
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CNS target engagement of high-dose DHA supplementation in older adults at risk for dementia: a randomised, double-blind, placebo-controlled trial.

EBioMedicine. 2026 Jun 18;:106316. Epub 2026 Jun 18
Authors: Yassine HN, Pour SG, Juarez M, Arrelanas IC, Ali N, Dikeman D, Sanchez A, Park J, Kerman B, Duro MV, Asante I, Louie S, Kono N, D'Orazio LM, Chui H, Mack WJ, Harrington MG, Braskie MN, Schneider LS
PubMed: 42315445
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Strategic Amyotrophic Lateral Sclerosis Australia-Systems Genomics Consortium (SALSA-SGC): cohort profile.

BMJ Open. 2026 Jun 18;16(6):e110906.
Authors: Henders AK, Ziser L, Garton FC, Adams L, Ernst K, Furlong S, Heads JA, Heggie S, Krasniqi R, Bhadravathi Lokeshappa M, Mazumder S, McNamara E, MacShane A, Mekhael L, Nunn L, Orden B, Ryder J, Thorpe K, Toubia M, Wallace LM, Wickremeratne D, Windebank E, Benyamin B, Ngo S, Nicholson G, Pamphlett R, Steyn FJ, Visscher PM, Willams KL, Henderson R, Kiernan MC, Laing N, Mathers S, McCombe PA, Needham M, Rowe D, Schultz D, Talman P, Vucic S, Blair IP, McRae AF, Wray NR
PubMed: 42315356
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Explainable AI for MRI Alzheimer's disease classification: A comparative analysis.

Neuroimage. 2026 Jun 18;:122043. Epub 2026 Jun 18
Authors: Persson S, Svenberg H, Rial AM, Ferreira D, Moreno R, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42314917
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Air pollution is linked to divergent cortical thickness patterns in brain regions vulnerable to Alzheimer's disease.

Neurotoxicology. 2026 Jun 18;:103495. Epub 2026 Jun 18
Authors: Salminen LE, Wang X, Petkus AJ, Fennema-Notestine C, Elman JA, Hagler DJ Jr, Kaufman JD, Millstein J, Braskie MN, Liu J, Cho HJ, Kothapalli D, Thompson PM, Beavers DP, Espeland MA, Gatz M, Resnick SM, Frahmand I, Rapp SR, Finch CE, Chen JC, Kremen WS, Franz CE
PubMed: 42314912
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Molecular mechanism of dopaminergic neuron injury induced by PAHs: Regulation of AhR-RORα/Nrf2 axis and α-syn O-GlcNAc modification.

Neurotoxicology. 2026 Jun 18;115:103494. Epub 2026 Jun 18
Authors: Gao Y, Duan C, Zheng X, Qu L
PubMed: 42314911
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Folding pathways and force-induced unfolding of neurodegeneration associated GGGGCC microsatellite repeat RNA revealed by molecular simulations.

Int J Biol Macromol. 2026 Jun 18;:153101. Epub 2026 Jun 18
Authors: Yadav P, Malik I, Joshi H
PubMed: 42314891
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Miro1 mutations disrupt cellular calcium homeostasis via dysregulation of mitochondria-ER-contact-sites, rendering iPSC-derived neurons more susceptible to lipid peroxidation.

Neurobiol Dis. 2026 Jun 18;:107492. Epub 2026 Jun 18
Authors: Bartalis AE, Genschmar J, Fitzgerald JC, Hermann A, Grossmann D
PubMed: 42314863
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S-acylation of TDP-43: PALMing down aggregation?

Cell Chem Biol. 2026 Jun 18;33(6):742-744.
Authors: Yang R, Fang Y
PubMed: 42314654
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Promoting Brain Health in the Context of Normal Aging and Mild Cognitive Impairment: A Tutorial.

Am J Speech Lang Pathol. 2026 Jun 18;:1-27. Epub 2026 Jun 18
Authors: Cohen ML, Lanzi AM, Rothbart A, Keatley E, Seagly KS, Strong KA, Paul D, Sohlberg MM
PubMed: 42314214
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Fluorescence Lifetime and Smartphone-Enabled Detection of Amyloid-β for Diagnosis and Staging in Alzheimer's Disease.

ACS Chem Neurosci. 2026 Jun 18; Epub 2026 Jun 18
Authors: Bhagavath KK, Ramesh M, Kumar Y, Mandal S, Ila H, Govindaraju T
PubMed: 42314111
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Status of Alzheimer's and Parkinson's Disease Detections and Treatments.

ACS Chem Neurosci. 2026 Jun 18; Epub 2026 Jun 18
Authors: Nguyen PH, Derreumaux P
PubMed: 42313891
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Language processing in Mandarin sentence repetition in people with Alzheimer's disease.

Int J Speech Lang Pathol. 2026 Jun 18;:1-14. Epub 2026 Jun 18
Authors: Lin YT, Lai YH
PubMed: 42313606
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GENIE: A Two-Stage Interpretable Deep Learning Framework for Revealing the High-Order Genetic Interaction Network of Alzheimer's Disease.

IEEE Trans Comput Biol Bioinform. 2026 Jun 18;PP Epub 2026 Jun 18
Authors: Yu G, Ying H, Liu J, Amin N, van Duijn CM, Yang Y
PubMed: 42313600
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Microglia-driven neuroinflammatory signaling in neurodegeneration: mechanisms and therapeutic opportunities.

Mol Biol Rep. 2026 Jun 18;53(1)
Authors: Saini K, Dhiman P
PubMed: 42313307
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Targeting brain rhythms to support cognition in aging: a systematic review and meta-analysis of tACS across healthy aging, mild cognitive impairment, and Alzheimer's disease.

Geroscience. 2026 Jun 18; Epub 2026 Jun 18
Authors: Freitas da Costa B, Reuwsaat K, Emele N, Carvalho CM, Caparelli-Dáquer E, Panizzutti R
PubMed: 42313252
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Radiomics-enhanced 18F-AV45 PET/MRI for integrative assessment and centiloid estimation of amyloid-β burden in Alzheimer's disease.

Eur Radiol Exp. 2026 Jun 18;10(1)
Authors: Yuan Z, Zhang J, Zhou Z, Chen X, Qi N, Wang W, Cheng X, Lin Y, Zhao J
PubMed: 42313223
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Exercise-Driven NRF2 Activation as a Systemic Neuroprotective Strategy: Integrating Redox Biology, Muscle-Brain Crosstalk, and Therapeutic Targeting in Neurodegeneration.

Biochem Genet. 2026 Jun 18; Epub 2026 Jun 18
Authors: Deng P, Deng W, Wang L, Ye W, Li S
PubMed: 42313222
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Alzheimer's Disease and MERC Dysfunction: Integrating Mechanisms, Biomarkers, and Therapeutic Strategies.

Mol Neurobiol. 2026 Jun 18;63(1)
Authors: Kashif M, Majumder D
PubMed: 42313219
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Unraveling Aberrant Metabolic Patterns in Alzheimer's Disease Subtypes: From Perturbed Metabolic Pathways to Candidate Drug Targets.

Mol Neurobiol. 2026 Jun 18;63(1)
Authors: Lüleci HB, Jones A, Neff RA, Bennett DA, Zhang B, Çakır T, Thambisetty M
PubMed: 42313214
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Effects of Site-Specific Glycation on α-Synuclein.

ACS Chem Biol. 2026 Jun 18; Epub 2026 Jun 18
Authors: Baldensperger T, Hampel A, Becker CF
PubMed: 42312953
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Coaggregation with Aβ Drives β-Sheet Formation in tau Microtubule-Binding Repeats.

Biomacromolecules. 2026 Jun 18; Epub 2026 Jun 18
Authors: Huang F, Liu Y, Wang Y, Lv Z, Xu J, Zhang J, Ding F, Sun Y
PubMed: 42312952
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Qualitative Clock-Drawing Errors Across Dementia Etiologies and Mild Cognitive Impairment: A Clinically Interpretable Six-Class Framework.

CNS Spectr. 2026 Jun 18;:1-28. Epub 2026 Jun 18
Authors: Banik A, Pal S, Pal A, Pal M, Dutta I, Roy D, Chattopadhyay A, Benito-León J
PubMed: 42312459
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The evolving burden of early-onset Alzheimer's disease and other dementias in BRICS countries: Insights from the Global Burden of Disease Study 2023 and projections to 2035.

J Alzheimers Dis. 2026 Jun 18;:13872877261460745. Epub 2026 Jun 18
Authors: Yang L, Zeng J, Huang L, Li L
PubMed: 42312433
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Role of suvorexant in Alzheimer's disease: Targeting sleep, orexin signaling, and disease pathophysiology.

J Alzheimers Dis. 2026 Jun 18;:13872877261461161. Epub 2026 Jun 18
Authors: Ahmed Abbasi A, Norouziyan F, Moradikor N
PubMed: 42312432
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Metabolic context modulates neuroinflammation: Type 2 diabetes mellitus moderates the association of interleukin-8 with amyloid pathology and cognitive decline in mild cognitive impairment.

J Alzheimers Dis. 2026 Jun 18;:13872877261457565. Epub 2026 Jun 18
Authors: Kim EW, Alzheimer's Disease Neuroimaging Initiative
PubMed: 42312374
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Association between renin angiotensin system and cognitive outcomes over 15 years: The Look AHEAD study.

J Alzheimers Dis. 2026 Jun 18;:13872877261458824. Epub 2026 Jun 18
Authors: Yasar S, Anderson A, Hayden KM, Carmichael OT, Clark JM, Carlson MC, Asby DJ, Kehoe PG, Miners S, Espeland MA
PubMed: 42312371
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Why Deep Cervical Lymphovenous Anastomosis for Alzheimer Disease Lacks Scientific Foundation.

J Craniofac Surg. 2026 Jun 17; Epub 2026 Jun 17
Authors: Kim MS, Kang D
PubMed: 42302727
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Targeting the Nrf2 Signaling Pathway: A Review of Traditional Chinese Medicine for Alzheimer's Disease.

Am J Chin Med. 2026 Jun 17;:1-29. Epub 2026 Jun 17
Authors: Liu M, Hong H, Zhang X, Ren J, Tang C
PubMed: 42299502
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Why large-scale randomized trials of live-attenuated shingles vaccination for dementia prevention are urgently needed.

Nat Med. 2026 Jun 17; Epub 2026 Jun 17
Authors: Geldsetzer P
PubMed: 42310440
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iSCORE-PD: an isogenic stem cell collection to research Parkinson's disease.

Nat Commun. 2026 Jun 17; Epub 2026 Jun 17
Authors: Busquets O, Li H, Syed KM, Jerez PA, Dunnack J, Lo Bu R, Verma Y, Pangilinan GR, Martin A, Straub J, Du Y, Simon VM, Poser S, Bush Z, Diaz J, Sahagun A, Gao J, Hong S, Hernandez DG, Levine KS, Pochet N, Booth EO, Blanchette M, Bateup HS, Rio DC, Blauwendraat C, Hockemeyer D, Soldner F
PubMed: 42310027
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Plant-based neuroprotection against memory impairment: Insights from Drosophila melanogaster models of neurodegenerative diseases.

Neuroscience. 2026 Jun 17;610:255-272. Epub 2026 Jun 17
Authors: Cynthia Irene Kasi, Azhagu Saravana Babu Packirisamy, Meivelu Moovendhan
PubMed: 42309440
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P1642-1, a novel pancreatic polypeptide analogue, ameliorates cognitive impairment in 5 ×FAD mice and is associated with enhanced PINK1/Parkin-related mitophagy.

Peptides. 2026 Jun 17;199:171501. Epub 2026 Jun 17
Authors: Zhang H, Wei Y, Liu E, Sun H, Flatt P, Gault V, Irwin N, Hölscher C, Hao L, Zhang Z
PubMed: 42309369
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Novel aptamers targeting heparan sulfate for delivery of RNA therapeutics in Alzheimer's disease.

Prog Biomed Eng (Bristol). 2026 Jun 17; Epub 2026 Jun 17
Authors: Mehmood A, Shah AZ, Martinez Juarez JA, Liu X, Jiang H, Wang X
PubMed: 42309126
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Limiting neurodegeneration in ALS: A phosphatase paves the way.

Neuron. 2026 Jun 17;114(12):2073-2075.
Authors: Rugarli EI, Langer T
PubMed: 42309005
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D-chiro-inositol modulates brain insulin-related signaling and reduces amyloid burden, neuroinflammation and cognitive decline in preclinical models of Alzheimer's disease.

Biomed Pharmacother. 2026 Jun 17;201:119629. Epub 2026 Jun 17
Authors: Pacheco-Sánchez B, López-Gambero AJ, Gavito AL, Rivera P, Suárez J, Sanjuan C, Nilsson P, Tambaro S, de Fonseca FR
PubMed: 42308924
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Attention Networks Connectivity After Cognitive Rehabilitation in Alzheimer's Disease.

J Geriatr Psychiatry Neurol. 2026 Jun 17;:8919887261462178. Epub 2026 Jun 17
Authors: Salmon E, Bahri MA, Kurth S, Collette F, Phillips C, Majerus S, Lekeu F, Quittre A, Wojtasik V, Olivier C, Godichard V, Bastin C
PubMed: 42308323
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A multi-organ metabolomics atlas reveals molecular dysregulations in Alzheimer's disease mouse models.

Cell Rep. 2026 Jun 17;45(6):117499. Epub 2026 Jun 17
Authors: Zuffa S, Allaband C, Charron-Lamoureux V, Caraballo-Rodriguez AM, Patan A, Mohanty I, Agongo J, Bostick JW, Connerly TJ, Thron T, Needam BD, de Castro Fonseca M, Benitez RS, Hansen L, Tubb H, Cao J, Kalecký K, Bottiglieri T, MahmoudianDehkordi S, Schimmel L, Kueider-Paisley A, Graham SF, Siegel D, Wang M, Knight R, Kaddurah-Daouk R, Dorrestein PC, Mazmanian SK, Alzheimer Gut Microbiome Project Consortium
PubMed: 42308105
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EIGNN: An Explainable Imaging-Genetic Neural Network for Robust Alzheimer's Disease Risk Prediction.

IEEE Trans Med Imaging. 2026 Jun 17;PP Epub 2026 Jun 17
Authors: Zhang ZC, Cai Z, Zhao X, Cao J, Chen F, Ding J, Yang YT, Zhao XM
PubMed: 42308083
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Updates and validation of the Compi RNA-seq pipeline with a case study in Alzheimer's disease.

J Integr Bioinform. 2026 Jun 17; Epub 2026 Jun 17
Authors: Di Gerlando R, Gagliardi S, López-Fernández H
PubMed: 42308055
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Beyond Binary-The Case for Amyloid Centiloid Quantification.

JAMA. 2026 Jun 17; Epub 2026 Jun 17
Authors: Chin NA, Erickson CM, Grill JD, Rabinovici GD
PubMed: 42307963
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PCSK9 in bridging metabolism and neurodegeneration: a new paradigm for alzheimer's treatment.

Metab Brain Dis. 2026 Jun 17;41(1)
Authors: Sood S, Singh S, Singh TG
PubMed: 42307833
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Neuroinflammation mediated repurposing of clemastine for Alzheimer's disease through network pharmacology, molecular dynamics, and experimental validation studies.

Inflammopharmacology. 2026 Jun 17; Epub 2026 Jun 17
Authors: Soni S, Sarkar S, Tripathi P, Maurya S, Kaur G, Haque S
PubMed: 42307826
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Single-cell Transcriptomics Reveals that the SORBS1/FBXO22/BAG3 Axis Drives Astrocyte Senescence via Calcium Signaling and Affects Alzheimer's Disease-Related Neuronal Damage.

Neuromolecular Med. 2026 Jun 17;28(1)
Authors: Li Y, He X
PubMed: 42307825
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Glycogen Synthase Kinase-3β Inhibition Ameliorates Synaptic and Mitochondrial Dysfunction in a Sporadic Alzheimer's Disease-Like Model.

Mol Neurobiol. 2026 Jun 17;63(1)
Authors: Wang YH, Ding PL, Qin H, Zhang KX, Ge JW, Wu DH, Xie L, Liang K
PubMed: 42307791
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Choroidal Changes in Cerebral Amyloid Angiopathy Studied by Optical Coherence Tomography Angiography.

Transl Stroke Res. 2026 Jun 17;17(4)
Authors: Ye J, Ye X, Jia Y, Li X, Liu X, Zhu S, Huang S
PubMed: 42307684
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Gut microbiota and immune modulation: role in neurodegenerative disorders and cancer.

Mol Biol Rep. 2026 Jun 17;53(1)
Authors: Dogra KA, Sharma M, Ghosh N, Kaur G, Singh J, Sinha P
PubMed: 42307649
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A Phase-Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease-Associated Protein Aggregation and Guides Suppressor Design.

Adv Sci (Weinh). 2026 Jun 17;:e76118. Epub 2026 Jun 17
Authors: Sio JS, Loo WX, Loo YS, Tan WX, Lim HX, Liu H, Ng CS
PubMed: 42307331
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Alzheimer detection using multivariate decomposition of EEG signals and BDEO feature selection: with lobe-wise and overall feature analysis.

Comput Methods Biomech Biomed Engin. 2026 Jun 17;:1-25. Epub 2026 Jun 17
Authors: Sharma D, Sarkar AK
PubMed: 42307318
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Brain activity in an end-stage ALS patient suggests the presence of an unresponsive wakefulness syndrome.

Amyotroph Lateral Scler Frontotemporal Degener. 2026 Jun 17;:1-7. Epub 2026 Jun 17
Authors: Frycz S, Więcławski W, Skotniczny M, Binder M
PubMed: 42307135
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Diagnosis and management of frontotemporal dementia: a narrative review.

Neurodegener Dis Manag. 2026 Jun 17;:1-26. Epub 2026 Jun 17
Authors: Cenacchi V, Lombardo T, Palacino F, Cattaruzza T, Manganotti P, Benussi A
PubMed: 42306859
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Fucoxanthin Promotes Longevity and Neuroprotection in Caenorhabditis elegans via DAF-16 and Autophagy Pathways.

Rejuvenation Res. 2026 Jun 17;:15491684261460844. Epub 2026 Jun 17
Authors: Kim S, Park SK
PubMed: 42304897
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Targeting lysosomal pH restores mitochondrial quality control in GBA1-mutant Parkinson's disease.

Transl Neurodegener. 2026 Jun 17;15(1)
Authors: Sheshadri P, Costa-Besada MA, Fisher A, Kiraly S, Singh K, Kourouzidou I, Blacker TS, Zeng J, Shirihai OS, Grinstaff MW, Duchen MR
PubMed: 42310725
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Mid-to-late-life social network size and resilience to neurodegeneration: The Framingham Heart Study.

BMC Neurol. 2026 Jun 17; Epub 2026 Jun 17
Authors: Ho K, Hwang PH
PubMed: 42310578
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Plasmalogens in Alzheimer's Disease: A Narrative Review of Dietary Sources, Metabolism, and Neuroprotective Mechanisms.

J Agric Food Chem. 2026 Jun 17; Epub 2026 Jun 17
Authors: Zhang Y, Chen J, Jiang J, Yang N, Guo S, Gao F, Zhang C, Weng Q, Xiao H, Luo J, Chen J, Shen Q, Shen G, Ji L
PubMed: 42310520
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Biomarker Based ARIA Stress Test: A Proposed Conceptual Framework for Dynamic Biomarker-Guided ARIA Risk Stratification in Anti-Amyloid Immunotherapy for Alzheimer's Disease.

J Mol Neurosci. 2026 Jun 16;76(3)
Authors: Fang S, Chen S
PubMed: 42298214
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The Association Between Alzheimer's Disease-Related Biomarkers And Parkinson's Disease Based On Single-Cell Sequencing Analysis Combined With Mendelian Randomization.

J Mol Neurosci. 2026 Jun 16;76(3)
Authors: Duan X, Huang D, Zhong H, Guo X, Lu X, Wu J, Huang L
PubMed: 42298115
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The lung-brain axis in neurodegeneration: inflammatory, immune, and vascular mechanisms with therapeutic implications.

Inflammopharmacology. 2026 Jun 16; Epub 2026 Jun 16
Authors: Al-Shami AS, Anwar MM
PubMed: 42298083
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Baseline amyloid deposition phenotypes inform the spatial distribution of early amyloid clearance with lecanemab in Alzheimer's disease.

Eur J Nucl Med Mol Imaging. 2026 Jun 16; Epub 2026 Jun 16
Authors: Dou X, Hu D, Wang J, Zhong Y, Yu C, Zhan H, Chen Y, Zhou R, Zhang X, Zhang B, Zhou J, Tian M, Zhang H, Yan Y, Jin C
PubMed: 42297931
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Explainable EEG-based machine learning for early diagnosis of Alzheimer's disease and frontotemporal dementia.

Sci Rep. 2026 Jun 16; Epub 2026 Jun 16
Authors: Saeed F, Aldera S
PubMed: 42297902
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Summary for Patients: Dementia Risk After Recombinant Herpes Zoster Vaccination in Older Adults With a Recent Skilled-Nursing Facility Stay.

Ann Intern Med. 2026 Jun 16; Epub 2026 Jun 16
Authors:
PubMed: 42296504
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Dementia Risk After Recombinant Herpes Zoster Vaccination in Older Adults With a Recent Skilled-Nursing Facility Stay : A Target Trial Emulation.

Ann Intern Med. 2026 Jun 16; Epub 2026 Jun 16
Authors: Hayes KN, Harris DA, McConeghy KW, Grove LR, Joshi R, Han L, Davidson HE, Chachlani P, Bayer TA, Singh M, Abul Y, DeVone F, Gravenstein S
PubMed: 42296498
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Long-Term Blood Pressure Variability in Cerebral Amyloid Angiopathy is Associated with Ischemic Brain Injury and Cognitive Decline.

J Am Heart Assoc. 2026 Jun 16;15(12):e039087. Epub 2026 Jun 15
Authors: Sveikata L, Zanon Zotin MC, Schoemaker D, Ma Y, Perosa V, Chokesuwattanaskul A, Charidimou A, Duering M, Gurol ME, Assal F, Greenberg SM, Viswanathan A
PubMed: 42294770
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Circulating lipids are related to longitudinal changes of ATN biomarkers for Alzheimer's disease.

Mol Psychiatry. 2026 Jun 16; Epub 2026 Jun 16
Authors: Kim JP, Nho K, Wang T, Huynh K, Arnold M, Risacher SL, Bice PJ, Han X, Kristal BS, Blach C, Baillie R, Kastenmüller G, Meikle PJ, Saykin AJ, Kaddurah-Daouk R, Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s Disease Metabolomics Consortium (ADMC)
PubMed: 42304066
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Nickel(II) and Zinc(II) Binding to Tau Protein Fragments Containing Histidine and Cysteine.

Biol Trace Elem Res. 2026 Jun 16; Epub 2026 Jun 16
Authors: Mazhar F, Piskolti N, Kovács V, Várnagy K
PubMed: 42303860
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Retraction notice to "Exploring the molecular mechanisms of MSC-derived exosomes in Alzheimer's disease: Autophagy, insulin and the PI3K/Akt/mTOR signaling pathway" [Biomedicine & Pharmacotherapy 176 (2024) 116836].

Biomed Pharmacother. 2026 Jun 16;:119641. Epub 2026 Jun 16
Authors: Ebrahim N, Al Saihati HA, Alali Z, Aleniz FQ, Mahmoud SY, Badr OA, Dessouky AA, Mostafa O, Hussien NI, Farid AS, El-Sherbiny M, Salim RF, Forsyth NR, Ali FE, Alsabeelah NF
PubMed: 42303509
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Chinese herbal and natural compounds for Parkinson's disease: Myth or truth.

J Ethnopharmacol. 2026 Jun 16;370:122047. Epub 2026 Jun 16
Authors: Zhang R, Chen Y, Qian Y, Zhu C, Yang J, Zhang J
PubMed: 42302937
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TGFb signaling promotes astroglial activation and TDP-43 proteinopathy in organoid models of frontotemporal lobar degeneration.

J Clin Invest. 2026 Jun 16; Epub 2026 Jun 16
Authors: Ramsey AC, Tang XY, Macias MJ, Nano PR, Lu R, Benito B, Lau CM, Park J, Zhang J, Beatty W, Mukhtar T, Kriegstein AR, Bhaduri A, Marsan E, Huang EJ
PubMed: 42302828
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Orbitofrontal atrophy on MRI appears to be an indicator of C9orf72 repeat expansion status in FTD.

J Neuroradiol. 2026 Jun 16;53(5):101575. Epub 2026 Jun 16
Authors: Yli-Anttila N, Solje E, Aho K, Katisko K, Kivisild A, Soppela H, Krüger J, Hartikainen P, Lötjönen J, Hakumäki J
PubMed: 42302493
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Detecting amyloid-β pathology in subjective cognitive decline using plasma and CSF biomarkers.

EBioMedicine. 2026 Jun 16;129:106331. Epub 2026 Jun 16
Authors: Contador J, Pozzi FE, Sánchez-Benavides G, Fernández-Arcos A, Lantero-Rodríguez J, Montoliu-Gaya L, Minguillon C, Fauria K, González-Escalante A, Ortiz-Romero P, Blasco-Forniés H, de Diego-Osaba M, Jiménez Moyano E, Quijano-Rubio C, Kollmorgen G, Le Bastard N, Nadal A, Vanmechelen E, Jeromin A, Torres-Torronteras J, Ashton NJ, Zetterberg H, Blennow K, Gispert JD, Molinuevo JL, Del Campo M, Grau-Rivera O, Suárez-Calvet M, β-AARC Study collaborators
PubMed: 42302428
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Lupeol in neurodegenerative and neuropsychiatric disorders: Mechanisms and translational perspectives.

Biomed Pharmacother. 2026 Jun 16;201:119673. Epub 2026 Jun 16
Authors: Al-Abboodi AR, Azman KF
PubMed: 42302369
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Considerations for the selection and phenotyping of mouse models for the study of Alzheimer's disease.

STAR Protoc. 2026 Jun 16;7(3):104633. Epub 2026 Jun 16
Authors: Boyanova S, Katsouri L, Krupic J, Hair K, Wang SH, Wiseman FK
PubMed: 42301821
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Protocol for expressing and purifying recombinant full-length Tau by combining affinity chromatography with preparative HPLC.

STAR Protoc. 2026 Jun 16;7(3):104617. Epub 2026 Jun 16
Authors: Jing R, Mahapatra S, Bimali A, Herlory M, Walczak MA
PubMed: 42301817
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Cofilin 1-138 Promotes Mitochondrial Dysfunction and Synaptic Degeneration in Parkinson's Disease.

Mol Neurobiol. 2026 Jun 16;63(1)
Authors: Zhang D, Chen Y, Zhang H, Liu H, Wang D, Li Q, Qin H, Wan Y, Yan M
PubMed: 42301566
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Neuropathological study of the effects of aducanumab anti-Aβ immunotherapy on patients with Alzheimer's disease.

Acta Neuropathol. 2026 Jun 16;151(1)
Authors: Welikovitch LA, Oakley DH, Bennett RE, Serrano-Pozo A, Zhu H, Ruiz-Uribe NE, Zwang TJ, Chibnik LB, Gomez-Isla T, Frosch MP, Marks DS, Salloway S, Bernick C, Greeley D, Latimer CS, Nolan A, Hutchison RM, Rubel CE, Bussiere T, Plowey ED, Keene CD, Hyman BT
PubMed: 42301522
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Correction: A comparative study of dietary curcumin, nanocurcumin, and other classical amyloid‑binding dyes for labeling and imaging of amyloid plaques in brain tissue of 5×-familial Alzheimer's disease mice.

Histochem Cell Biol. 2026 Jun 16;164(1)
Authors: Maiti P, Hall TC, Paladugu L, Kolli N, Learman C, Rossignol J, Dunbar GL
PubMed: 42301495
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The Noradrenergic Brain in Parkinson's Disease.

Curr Neurol Neurosci Rep. 2026 Jun 16;26(1)
Authors: Pasquini J, Palermo G, Pavese N, Ceravolo R
PubMed: 42301334
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Modeling the organizational heterogeneity of cholesterol-enriched microdomains in the neuronal membranes of gray and white matter of Alzheimer's brain: a computational lipidomics study.

Soft Matter. 2026 Jun 16; Epub 2026 Jun 16
Authors: Peesapati S, Chakraborty S
PubMed: 42300919
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Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS.

Ann Clin Transl Neurol. 2026 Jun 16; Epub 2026 Jun 16
Authors: Calma AD, Pavey N, Tsuji Y, Ghapar AA, Bos MA, Orden B, Lee G, Mekhael L, Ryder J, Silva CS, McDonald D, Kakar F, Yiannikas C, Kiernan MC, Brown DA, Menon P, Vucic S
PubMed: 42300806
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Adverse events of Alzheimer's disease patients treated with memantine-based therapies: A disproportionality analysis of the FAERS database based on the MY FAERS platform.

J Alzheimers Dis. 2026 Jun 16;:13872877261458818. Epub 2026 Jun 16
Authors: Wang X, Zhang W, He J, Zhang X, Wang R, Li Z
PubMed: 42300750
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Language and communication disorders in dementia with Lewy bodies versus Alzheimer's disease: Objective screening and subjective perspectives of patients, their caregivers and clinicians.

J Alzheimers Dis. 2026 Jun 16;:13872877261458679. Epub 2026 Jun 16
Authors: Balohé M, Thivet J, Blanc F, Krein L, Jeon YH, Botzung A, Sanna L, Ravier A, Demuynck C, Muller C, Chabran É
PubMed: 42300742
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Primary and secondary prevention strategies for reducing population-level dementia burden: A microsimulation modeling study.

J Alzheimers Dis. 2026 Jun 16;:13872877261457937. Epub 2026 Jun 16
Authors: Van Rosmalen L, Brück CC, Wolters FJ, Handels R, De Kok IM
PubMed: 42300704
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Structural and load-dependent arterial stiffness are differentially associated with cognition or biomarkers of Alzheimer's disease and related dementias: The healthy brain study.

J Alzheimers Dis. 2026 Jun 16;:13872877261458779. Epub 2026 Jun 16
Authors: Deconne TM, Suerken CK, Lipford ME, Lockhart SN, Bateman JR, Espeland M, Rudolph MD, Rundle MM, Sutphen C, Register TC, Mielke MM, Pewowaruk R, Gepner AD, Baker LD, Craft S, Hughes TM
PubMed: 42300702
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Traumatic brain injury and late-life Alzheimer's disease neuropathology: Quantitative investigation in the Adult Changes in Thought study.

J Alzheimers Dis. 2026 Jun 16;:13872877261457138. Epub 2026 Jun 16
Authors: Selmanovic E, Gibbons LE, Folkerth RD, Keene CD, Nolan A, Crane P, Postupna N, Lee CS, Latimer CS, Ariza-Torres J, Hof PR, Dams-O'Connor K
PubMed: 42300698
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Plasma p-tau217 measured by the Elecsys automated immunoassay: Prospective validation in a heterogeneous memory clinic cohort.

J Alzheimers Dis. 2026 Jun 16;:13872877261459067. Epub 2026 Jun 16
Authors: Franco-Macías E, Noval-Padillo JÁ, Hervás-Navidad R, Espejo-Martínez B, Serrano-Gutiérrez C, Rodrigo-Herrero S, Méndez-Barrio C, Mendoza-Vázquez G, Carrera-Muñoz I, Marín-Romero B, Garzón-Maldonado F, Carazo-Barrios L, Rodríguez-Jiménez L, Martínez-Nogueras Á, Agüera-Morales E, Conde-Gavilán C, Jover AM, García-Navarro C, Iglesias-Espinosa M, Romera-Morales DJ, Cuartero-Rodríguez E, García-Roldán E, González-Acosta M, Almodóvar-Sierra Á, Marín-Cabañas M, Bernal Sánchez-Arjona M, García-Sánchez MI, Arriola-Infante JE, Arrabal-Gómez C, Oliver-Martos B, Serrano-Castro PJ, Fatela-Cantillo D
PubMed: 42300696
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Impacts of menopausal hormone therapy on Alzheimer's disease biomarkers: A systematic review.

J Alzheimers Dis. 2026 Jun 16;:13872877261456766. Epub 2026 Jun 16
Authors: Rodrigues AC, Valério FG, Moura CB, Da Silva AM, Tudella GC, Almeida SS, Gomes AC, Oliveira CE, Apóstolos-Pereira SL, Santos DH
PubMed: 42300694
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PARK(ing) time-How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease.

FEBS Lett. 2026 Jun 16; Epub 2026 Jun 16
Authors: Zientara K, Skoczek K, Pyza E, Damulewicz M
PubMed: 42299891
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Alzheimer's disease and related dementias state policies and mortality in the United States: A descriptive study.

J Alzheimers Dis. 2026 Jun 16;:13872877261453609. Epub 2026 Jun 16
Authors: Churchill N, Le TT, Nianogo RA
PubMed: 42299870
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Identification of candidate diagnostic biomarkers and gene networks for moderate stages of Alzheimer's disease in fusiform gyrus exhibiting neurofibrillary tangles.

J Alzheimers Dis. 2026 Jun 16;:13872877261452277. Epub 2026 Jun 16
Authors: Beh-Pajooh A
PubMed: 42299852
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Prediction of Alzheimer's disease risk factors from retinal images via deep learning: Development and validation of biologically relevant morphological associations in the UK Biobank.

J Alzheimers Dis. 2026 Jun 16;:13872877261457650. Epub 2026 Jun 16
Authors: Leem S, Yang Y, Woods AJ, Fang R
PubMed: 42299837
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Deep brain stimulation in alpha-synuclein models of Parkinson's disease: Bridging the translational gap.

J Parkinsons Dis. 2026 Jun 16;:1877718X261459876. Epub 2026 Jun 16
Authors: Kondrataviciute L, Weber H, Kapadia M, Aguirre-Padilla DH, Fauser M, Valiante TA, Hutchison WD, Milosevic L, Storch A, Kalia LV, Kalia SK
PubMed: 42299658
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Amyloid beta aggregation seeding activity as a new biomarker for Alzheimer's disease.

Chin Med J (Engl). 2026 Jun 16; Epub 2026 Jun 16
Authors: Song Y, Xie S, Li T, Li Y, Nie S, Wang Z, Ma J, Jia J
PubMed: 42299128
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Transcranial pulse stimulation modulates spectral signatures of Alzheimer's disease in the 3×Tg-AD mouse model.

Alzheimers Res Ther. 2026 Jun 16; Epub 2026 Jun 16
Authors: Gezginer I, Karakatsani ME, Nanda P, Chalasani P, Kindler D, Storz R, Belau M, Ni R, Schratt G, Deán-Ben XL, Razansky D
PubMed: 42298621
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The time interval from amyloid to tau PET positivity varies by age, sex and APOE-ε4 status.

J Prev Alzheimers Dis. 2026 Jun 16;13(8):100622. Epub 2026 Jun 16
Authors: Milà-Alomà M, Hausle I, Petersen KK, Thropp P, Schindler SE, Tosun D, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42309020
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HSP90 is involved in curcumin-mediated inhibition of tau aggregation.

Biochem Biophys Res Commun. 2026 Jun 16;829:154140. Epub 2026 Jun 16
Authors: Kam MK, Kim JW, Choi JY, Koh YH, Jo C
PubMed: 42308766
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From aging to Alzheimer's disease: concordant brain DNA methylation changes in late life.

Genome Med. 2026 Jun 16; Epub 2026 Jun 16
Authors: Lukacsovich D, Young JI, Gomez L, Schmidt MA, Zhang W, Kunkle BW, Chen XS, Martin ER, Wang L, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42304519
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A small molecule modulating heterogeneous amyloid-β isoforms improves cognitive and pathological outcomes in acute and 5XFAD Alzheimer's disease models.

Alzheimers Res Ther. 2026 Jun 16; Epub 2026 Jun 16
Authors: Kim J, Ku D, Park I, Ye S, Cho I, Park M, Seo W, Lee S, Kim HY, Kim I, Kim Y
PubMed: 42304429
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Taxifolin-Functionalized Rivastigmine Liposomal Nanoformulation: A Synergistic Approach for Alzheimer's Disease Management.

Pharm Nanotechnol. 2026 Jun 16; Epub 2026 Jun 16
Authors: M M, Kaliyaperumal R
PubMed: 42312515
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A High-Affinity NIR Fluorescent Probe for Aβ Oligomers Enables Theranostics Through Disrupting Membrane Interaction and Aggregation.

ACS Chem Neurosci. 2026 Jun 15; Epub 2026 Jun 15
Authors: Yang M, Wang Y, Deng J, Wu Q, Wang Z, Meng Q, Wang P, Yang J
PubMed: 42298288
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Autophagy protein links ageing and Alzheimer disease.

Nat Rev Neurol. 2026 Jun 15; Epub 2026 Jun 15
Authors: Fyfe I
PubMed: 42298113
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Mechanisms of increased Alzheimer's disease pathology with R47H and R62H TREM2 variants.

Acta Neuropathol. 2026 Jun 15;151(1)
Authors: Fancy NN, Willumsen N, Chau VM, Boulger SL, Whitwell HJ, Wang W, Avot B, Thomas M, Talbot-Martin J, Tsartsalis S, Khozoie C, McGarry A, Schneegans E, Yagoubi R, Cheung TK, Papageorgopoulou M, Adair E, Cooper B, Davey K, Smith AM, Scotton W, Hardy J, Matthews PM, Jackson JS
PubMed: 42298074
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Hospital-treated infection associated with Alzheimer's disease pathology: underlying mechanisms.

Mol Psychiatry. 2026 Jun 15; Epub 2026 Jun 15
Authors: Barichello T, Scaini G, Tayyab M, Dal-Pizzol HR, Petronilho F, Dal-Pizzol F
PubMed: 42297936
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Association between the use of anti-herpetic drugs and subsequent initiation of Alzheimer's disease drug treatment: Dutch population-based inception cohort study.

BMJ Open. 2026 Jun 15;16(6):e114033.
Authors: Alghamdi A, Balafas S, Bos JH, van Munster BC, Rafie K, Dolga AM, Hak E
PubMed: 42297456
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Current progress in the use of pyrazole-containing compounds for neuroprotection as a strategy to counteract neurodegeneration.

Biochem Pharmacol. 2026 Jun 15;251(Pt 2):118161. Epub 2026 Jun 15
Authors: Bastos IM, Moreira DR, Rebelo S, Silva VL
PubMed: 42297218
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The selective vulnerability of the left fimbria in cognitively normal APOE ε4 carriers: a localized structural correlate of high genetic risk for Alzheimer's disease.

Behav Brain Res. 2026 Jun 15;513:116336. Epub 2026 Jun 15
Authors: Suo Y, Wang L, Zhao Y, Wen Q, Feng Q, Zhang H, Ding Z
PubMed: 42297216
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An automated workflow for quantifying the formation of synuclein aggregates in human dopaminergic neurons.

Methods. 2026 Jun 15;254:29-41. Epub 2026 Jun 15
Authors: Han C, Nguyen-Renou E, Benaliouad F, Luo W, Chen CX, Alluli A, Villegas L, Beitel LK, Shlaifer I, Reintsch WE, Krahn AI, Cid Pellitero ED, Fon EA, Durcan TM
PubMed: 42297199
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From prediction to mechanism: Explainable AI uncovers plasma and CSF proteomic signatures of Alzheimer's disease.

J Proteomics. 2026 Jun 15;331:105698. Epub 2026 Jun 15
Authors: Donmez TB, Mansour M
PubMed: 42297098
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Basal Ganglia and Thalamic Volumes as MRI Markers of Motor and Cognitive Dysfunction in Parkinson's Disease.

Rofo. 2026 Jun 15; Epub 2026 Jun 15
Authors: Yıldız H, Atalay B, Özdilek B
PubMed: 42296997
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Beyond target engagement: RNA therapeutics and the neuroimmune challenge in tauopathies.

J Prev Alzheimers Dis. 2026 Jun 15;13(7):100626. Epub 2026 Jun 15
Authors: Breen EA
PubMed: 42296861
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Innate immune signaling as a potential pathomechanistic biomarker for distinct subtypes in amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener. 2026 Jun 15;:1-8. Epub 2026 Jun 15
Authors: Naumann M, Kretschmer S, Dorst J, Lapp H, Peikert K, Petri S, Gess B, Wolf C, Rödiger A, Smesny U, Pan-Montojo F, Kerschen P, Grehl T, Prudlo J, Regensburger M, Ludolph A, Günther R, Brenner D, Lee-Kirsch MA, Hermann A
PubMed: 42296226
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From Ambient Assistance to Data-Driven Precision in AI-Enabled Alzheimer's Care (2004-2025): A Bibliometric Perspective.

Gerontologist. 2026 Jun 15; Epub 2026 Jun 15
Authors: Du B, Li Q, Li X, Liu X, Zhang K, Gong Y, Song J, Wu H
PubMed: 42295865
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TDP-43 Aggregation: The Healthy-Toxic Balance of the Prion-Like Domain.

Adv Sci (Weinh). 2026 Jun 15;:e76119. Epub 2026 Jun 15
Authors: Zangrando L, Buratti E, Paron F
PubMed: 42295787
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Recent trends in anti-Alzheimer's potential of novel biologically active isatin analogues: synthetic strategies, structural activity relationship studies and molecular docking insights.

Mol Divers. 2026 Jun 15; Epub 2026 Jun 15
Authors: Nath R, Chakraborty A, Akhtar MJ, Maity I, Ganguly S, Nehra B, Ashique S, Khan SA, Tariq M, Bakshi S, Debnath B, Yasmin S, Khalilullah H, Ansari MY
PubMed: 42295692
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Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis.

Ann Clin Transl Neurol. 2026 Jun 15; Epub 2026 Jun 15
Authors: Jürs AV, Naumann M, Lehto A, Schön H, Kurth J, Prudlo J, Hermann A, Kasper E
PubMed: 42295687
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Epigallocatechin-3-gallate (EGCG) as a molecular chaperone and network rebalancer in neurodegenerative diseases.

Inflammopharmacology. 2026 Jun 15; Epub 2026 Jun 15
Authors: Farah H, Ahmed MH, Al-Hasnaawei S, Malathi H, Mishra S, Nanda A, Arora V, Chauhan AS
PubMed: 42295682
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Diagnosis and Prediction of Alzheimer's Disease via a High-Level Convolutional Block Attention Module-Residual Network.

Interdiscip Sci. 2026 Jun 15; Epub 2026 Jun 15
Authors: Rao C, Zhang X, Hou J
PubMed: 42295635
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Circ_0092222 is Enhanced in Alzheimer's Disease and Exacerbates Aβ-induced Neurotoxicity Through Sponging miR-331-3p.

Mol Neurobiol. 2026 Jun 15;63(1)
Authors: Guo Y, Chen P, Chen S, Xu N, Shi J, Li D, Zhang P
PubMed: 42295611
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Correction: Tailoring treatments: pharmacogenomics in the management of neurodegenerative diseases.

Acta Neurol Belg. 2026 Jun 15; Epub 2026 Jun 15
Authors: Roy KK, Kumari R, Upadhyay AK, Mohanty S
PubMed: 42295610
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Unlocking the aging brain: mTORC1 as a convergent integrator for neurodegeneration and therapeutic intervention.

Biogerontology. 2026 Jun 15;27(4)
Authors: Rejili M, Al-Kuraishy HM, Shokr MM, Batiha GE
PubMed: 42295556
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Biomarkers stewardship in parkinsonism: integrating alpha-synuclein seed amplification assays and neurofilament light chain into diagnostic pathways and patient communication.

J Neurol. 2026 Jun 15;273(7)
Authors: Leclercq V
PubMed: 42295486
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Expression of GPR34 in microglia remains stable in human Alzheimer's disease.

Acta Neuropathol. 2026 Jun 15;151(1)
Authors: Seiffer S, Rotter J, Brendler J, Ricken A, Detzer Z, Braune M, Schöneberg T, Schulz A, Winter K, Bechmann I
PubMed: 42295430
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Depression and anxiety modify cognitive concerns associated with amyloid and early clinical impairment.

Neuropsychology. 2026 Jun 15; Epub 2026 Jun 15
Authors: Stites SD, Schumann R, Shi Y, Mechanic-Hamilton D, Wolk DA, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42295275
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Neuronal resilience as an active and programmable property.

J Alzheimers Dis. 2026 Jun 15;:13872877261461252. Epub 2026 Jun 15
Authors: Acquarone E
PubMed: 42294922
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Design and Development of a Novel LXRβ/PPARδ Dual Agonist for Memory Impairment and Pathology in 3xTg-AD Animal Model of Alzheimer's Disease.

ACS Chem Biol. 2026 Jun 15; Epub 2026 Jun 15
Authors: Singh M, Steinke I, Crall N, Tamhankar S, Wibowo FS, Xavier J, Yue Z, Pondugula SR, Huang CJ, Griffett K, Smith FT, Chowdhury K, Suppiramaniam V, Amin RH
PubMed: 42294918
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Microplastics-Induced Gut Microbiota Dysbiosis Accelerates Alzheimer's-Like Pathology and Cognitive Decline via the Gut-Brain Axis.

Adv Sci (Weinh). 2026 Jun 15;:e76072. Epub 2026 Jun 15
Authors: Wu Z, Yang J, Zhang M, Li Y, Tu Z, Wang J, Yu JT, Guo K, Luo R
PubMed: 42294809
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Plasma neurofilament light chain and regional brain atrophy mediate the association of neuropsychiatric symptoms with cognition in Alzheimer's disease: evidence from two population-based studies.

Psychol Med. 2026 Jun 15;56:e192.
Authors: Wang YY, Zhu HY, Miao W, Wang ZX, Qin JJ, Song XH, Wang YH, Sun ZW, Zhou X, Yu XF, Zhu XQ, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42294788
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Oleanolic acid modulates neuronal regeneration through KLF5-mediated FGF13 mRNA degradation to alleviate Alzheimer's disease-like cognitive dysfunction.

J Mol Med (Berl). 2026 Jun 15;104(1)
Authors: Ren D, Xu J, Xiao L, Zhang T, Li B, Li R, Zhu H
PubMed: 42289606
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Investigating AD and non-AD [18F]flortaucipir distribution patterns in a memory clinic cohort.

Eur J Nucl Med Mol Imaging. 2026 Jun 15; Epub 2026 Jun 15
Authors: Piva F, Boccalini C, Ashton NJ, Zetterberg H, Blennow K, Frisoni GB, Veronese M, Garibotto V, Peretti DE
PubMed: 42289538
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Scalable CT-based prognostic modeling of dementia conversion in mild cognitive impairment.

Sci Rep. 2026 Jun 15;16(1)
Authors: Park S, Ahn J, Na DL, Kim HJ, Jang H, Kim JP, Kang SH, Yun J, Chun MY, Seo SW, Kwak K
PubMed: 42289414
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Designing polymer-peptide conjugates to target dipeptide repeat aggregates implicated in amyotrophic lateral sclerosis.

J Mater Chem B. 2026 Jun 15; Epub 2026 Jun 15
Authors: Gray VP, Cui Z, Klepsig M, Letteri RA
PubMed: 42300933
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Reply to: "Idebenone in Rapid Eye Movement Sleep Behavioral Disorder for Parkinson's Disease Prevention".

Mov Disord. 2026 Jun 15; Epub 2026 Jun 15
Authors: Li Y, Liu J
PubMed: 42298923
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Idebenone in Rapid Eye Movement Sleep Behavioral Disorder for Parkinson's Disease Prevention.

Mov Disord. 2026 Jun 15; Epub 2026 Jun 15
Authors: Tambasco N, Nigro P
PubMed: 42298919
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Plasma p-tau217 Versus p-tau181 in Parkinson's Disease: Differential Associations with Alzheimer's Disease-Related Neurostructural Changes and Cognitive Function.

Mov Disord. 2026 Jun 15; Epub 2026 Jun 15
Authors: Fiorenzato E, Cauzzo S, Musso G, Biundo R, Ceolin C, Cosma C, Fogliano CA, Meissner WG, Misenti V, Moz S, Nasi ML, Vianello F, Manara R, Montagnana M, Sergi G, Antonini A, OPA Working Group
PubMed: 42298873
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Development and validation of a harmonized memory score for multicenter Alzheimer's disease and related dementia research.

Alzheimers Res Ther. 2026 Jun 15; Epub 2026 Jun 15
Authors: Sanderson-Cimino M, Gross AL, Gaynor LS, Paolillo EW, Saloner R, Albert MS, Apostolova LG, Boersema B, Boxer AL, Boeve BF, Casaletto KB, Heuer HW, Forsberg LK, Hallgarth SR, Diaz VE, Clark LR, Eloyan A, Farias ST, Maillard P, Gonzales MM, Hammers DB, La Joie R, Cobigo Y, Wolf A, Hampstead BM, Mechanic-Hamilton D, Miller BL, Rabinovici GD, Ringman JM, D'Orazio LM, Rosen HJ, Ryman SG, Prestopnik JL, Salmon DP, Smith GE, DeCarli C, Rajan KB, Jin LW, Hinman JD, Johnson DK, Harvey DJ, Fornage M, Carrillo MC, Dickerson BC, Kramer JH, Staffaroni AM, ALLFTD consortium, MarkVCID study, LEADS consortium, and Diverse Vascular Contributions to Cognitive Impairment and Dementia (Diverse VCID) Study Investigators
PubMed: 42298651
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Advances in nano-TCM for Alzheimer's disease: lipid-based carriers integrated with innovative delivery strategies.

J Nanobiotechnology. 2026 Jun 15; Epub 2026 Jun 15
Authors: Deng L, Li H, Yang S, Chen F, Qiao J, Bao H, Wang X, Fang S, Xu B, Tang Z
PubMed: 42298558
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Tau profiling of brain extracellular vesicles reveals PHF6 peptide as core for pathological tau seeding in Alzheimer's disease.

J Biomed Sci. 2026 Jun 15;33(1)
Authors: Oosterlynck M, Fichter L, Leroux E, Eddarkaoui S, Bouillet T, Lefebvre C, Nguyen M, Maurage CA, Accart B, Dupré E, Landrieu I, Danis C, Lehmann S, Vialaret J, Buée L, Hirtz C, Colin M
PubMed: 42298542
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Generation of 4 human induced pluripotent stem cell lines (LUMCi070-A, -B, -C, and -D) from a patient with ischemic cerebral small vessel disease.

Stem Cell Res. 2026 Jun 14;95:104036. Epub 2026 Jun 14
Authors: Voesenek BJ, van der Graaf LM, Lesnik Oberstein SA, van Roon-Mom WM, Daoutsali E, Buijsen RA
PubMed: 42296843
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Concordance between domain-based neuropsychological profiles and clinical phenotypes in young-onset dementia.

Clin Neuropsychol. 2026 Jun 14;:1-15. Epub 2026 Jun 14
Authors: Renssen JW, Sikkes SA, van der Landen SM, Leeuwis AE, Groot C, van der Flier WM, Ponds RW, Pijnenburg YA
PubMed: 42289826
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Superoxide dismutase and glutathione interact to determine cognitive outcome among people with subjective cognitive decline (SCD): a prospective study.

Eur Arch Psychiatry Clin Neurosci. 2026 Jun 14; Epub 2026 Jun 14
Authors: Lin CH, Lane HY
PubMed: 42289601
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The effect of canagliflozin on hippocampal dendrite morphology in a model of Alzheimer's disease induced by intracerebroventricular injection of streptozotocin.

Brain Struct Funct. 2026 Jun 14;231(6)
Authors: Yazi S, Ozen B, Buldu B, Yalcin E, Karakose O, Cakmak O, Somunkiran S, Yananli HR, Sehirli US, Kirazli O
PubMed: 42289507
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Combination therapy of levodopa with safinamide is more effective than with rasagiline and zonisamide in Asian Parkinson's disease patients with motor fluctuations: a systematic review and network meta-analysis of randomized controlled trials.

J Neurol. 2026 Jun 14;273(7)
Authors: Wang Y, Wang XX, Yuan BJ, Li X, Zhang YL, Yang XH, Hou DL, Peng SJ, Li XJ, Feng Y, Zhou ZD, Tan EK, Wu YC
PubMed: 42289483
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A computational model to describe multi-regional brain architecture during neurodegeneration in Alzheimer's disease.

Sci Rep. 2026 Jun 14; Epub 2026 Jun 14
Authors: Li X, Rockall AG, Edison P, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Australian Imaging Biomarkers and Lifestyle (AIBL) Study, Aboagye EO
PubMed: 42289440
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Brain Metabolic Signatures of Amyloid-β and Tau Pathology in Corticobasal Syndrome: A Multimodal Biomarker Study.

Mov Disord. 2026 Jun 14; Epub 2026 Jun 14
Authors: Li XY, Lu JY, Shen Q, Zhao YX, Chan KW, Liu W, Ge JJ, Zhao J, Sun YM, Yen TC, Wu JJ, Zuo CT, Wang J, Liu FT, Progressive Supranuclear Palsy Neuroimage Initiative (PSPNI)
PubMed: 42289359
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Genetic suppressions of CRMP2 phosphorylation ameliorate α-synuclein accumulation in an α-synucleinopathy mouse model.

Neurosci Lett. 2026 Jun 14;883:138661. Epub 2026 Jun 14
Authors: Ayala Guevara V, Goshima Y, Ohshima T
PubMed: 42289231
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Current advances in PDGF isoform specificity and variable functions in aging-associated neurological disorders.

Neurobiol Dis. 2026 Jun 14;227:107488. Epub 2026 Jun 14
Authors: Wang J, Han T, Hu P, Hu S, Song J, Li S, Zhou Q, Luo A, Zeng L
PubMed: 42289203
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Phosphonates as Modulators of Brain Chemistry.

Med Res Rev. 2026 Jun 14; Epub 2026 Jun 14
Authors: Braga SS, Santos NE, Almeida-Santos M, Figueira FF, Almeida Paz FA
PubMed: 42288958
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Generation of an induced pluripotent stem cell line (NIMHi032-A) from a progressive supranuclear Palsy-Richardson's syndrome patient of Indian ethnicity.

Stem Cell Res. 2026 Jun 14;95:104037. Epub 2026 Jun 14
Authors: Ghanty R, Balaskar MO, Yadav R, Kamble N, Holla V, Pal PK, Datta I
PubMed: 42314572
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Seven-year progression of white matter hyperintensities and age-related cognitive change in healthy middle-aged and older adults.

Geroscience. 2026 Jun 13; Epub 2026 Jun 13
Authors: Liu J, Daugherty AM, Dahle CL, Ghisletta P, Raz N
PubMed: 42286380
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Recent advances in neurodegenerative diseases therapeutics: The inhibition of monoacylglycerol lipase strategy.

Neuroscience. 2026 Jun 13;610:198-206. Epub 2026 Jun 13
Authors: Mendoza-Camacho DM, Espinoza-Gutiérrez HA, Viveros-Paredes JM, Flores-Soto ME, Tejeda-Martínez AR
PubMed: 42285406
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α-Synuclein overexpression increases the tropism of pre-formed fibrils and MSA-patient derived seeds towards oligodendroglia.

Acta Neuropathol Commun. 2026 Jun 13; Epub 2026 Jun 13
Authors: Laursen AS, Lind-Holm Mogensen F, Folke J, Garnæs MF, Knecht LH, Brudek T, Olesen MV, Bidstrup M, Kaalund SS, Holst-Williams S, Willén K, Pinho M, Pritzkow S, Buell AK, Farzadfard A, Soto C, Fog K, Dalgaard LT, Sotty F, Aznar S
PubMed: 42288827
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Identification of TBXAS1 as a candidate biomarker and potential microglia-associated inflammatory regulator in Parkinson's disease.

Sci Rep. 2026 Jun 13; Epub 2026 Jun 13
Authors: Guan X, Zhao Q, Deng Y, Lu Z
PubMed: 42288542
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Proton pump inhibitor use and risk of dementia in a population-based cohort study.

Sci Rep. 2026 Jun 13; Epub 2026 Jun 13
Authors: Liu HH, Chen TI, Chen YC, Wang V, Yip PK, Lee FJ, Hsu WL, Lan YC
PubMed: 42288508
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Uncovering the Biological Mechanisms of TREM2 with Molecular Simulations: A Comprehensive Review and Perspective.

Prog Biophys Mol Biol. 2026 Jun 13; Epub 2026 Jun 13
Authors: Lietzke EE, Saeb D, Aldrich EC, de Menezes RF, Bruce KD, Sprenger KG
PubMed: 42288287
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Current status and challenges in targeting circulating amyloid-β carriers for Alzheimer's disease therapy.

Neuroscience. 2026 Jun 13;610:189-197. Epub 2026 Jun 13
Authors: Ren L, Luo XQ, Mi FY, Yu CY
PubMed: 42288184
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AQP4-Mediated Glymphatic Clearance: Sleep, Neurodegeneration, and the Translational Gap.

Neurosci Biobehav Rev. 2026 Jun 13;:106819. Epub 2026 Jun 13
Authors: Santerre M, Shcherbik N, Sawaya BE
PubMed: 42288169
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Tailored implementation of multidomain intervention to prevent cognitive impairment in community-dwelling older adults (Timi-Cog): A study protocol for a hybrid type 2 trial effectiveness-implementation study.

J Prev Alzheimers Dis. 2026 Jun 13;13(8):100623. Epub 2026 Jun 13
Authors: Huang Z, Shi C, Xue E, Qiu G, Jing Y, Wang Z, Ao X, Xu DR, Wang Y
PubMed: 42287975
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Eligibility of men vs. women in Alzheimer's trials: Inclusive vs. representative.

J Prev Alzheimers Dis. 2026 Jun 13;13(7):100625. Epub 2026 Jun 13
Authors: Grill JD, Gillen DL
PubMed: 42287775
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Focused ultrasound-mediated nanocarrier delivery across the blood-brain barrier for neurodegenerative diseases.

Biomed Pharmacother. 2026 Jun 13;201:119622. Epub 2026 Jun 13
Authors: Jaberi KR, Haghighi MR, Aligholi H, Takallu S, Asadi P, Mirzaei E, Jaberi AR, Sahraian A
PubMed: 42287757
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Evaluating early vs. late static SUVR windows of [¹⁸F]MK-6240 tau PET in Alzheimer disease: a head-to-head comparison study.

Eur J Nucl Med Mol Imaging. 2026 Jun 13; Epub 2026 Jun 13
Authors: Hu TW, Prince J, Zhou L, Wang XH, Tanzi EB, Khalafi M, Nehmeh SA, Pahlajani SS, Hojjati H, Glodzik L, Butler T, Chiang GC, Li Y
PubMed: 42287388
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Creutzfeldt-Jakob disease in the Philippines: diagnostic and management challenges from the first multicenter registry.

J Neural Transm (Vienna). 2026 Jun 13; Epub 2026 Jun 13
Authors: Ayo ST, Saranza G, Mabulay MK, Untalan L, Bilocura F, Dizon Z, Oliva PM, Ong JN, Ng A, Mata-Raciles C, Macabaya A, Lim B, Sage-Nolido AM, Serrano GK, Surdilla A, Pasco P, Kathleen M
PubMed: 42287369
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Fluid biomarkers in Cerebral amyloid angiopathy: current limitations and future directions.

Expert Rev Mol Diagn. 2026 Jun 13; Epub 2026 Jun 13
Authors: Del Chicca M, Mignani G, Iannaccone F, Piccarducci R, Giannini N, Tognoni G, Masi S, Ceravolo R, Siciliano G, Mancuso M, Baldacci F
PubMed: 42287242
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Beyond RSWA in prodromal α-synuclein disease: Do periodic limb movements signal potential early dopaminergic dysfunction?

Sleep Med. 2026 Jun 13;146:109086. Epub 2026 Jun 13
Authors: Gorantla S, Cesari M, Ferri R
PubMed: 42308678
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Author Correction: Exercise alleviates cognitive dysfunction in Alzheimer's disease mice via skeletal muscle-derived extracellular vesicles that enhance plaque clearance by microglia.

Nat Aging. 2026 Jun 12; Epub 2026 Jun 12
Authors: Lin J, Shao X, Shi T, Wang H, Zhang P, Zhou Y, Liu N, He Y, Fang D, Shi Y, Ma Y, Liu B, Gong W, Wu W, Peng R, Wang C, Shen T, Jiang Z, Ben Y, Qin J, Xu Z, Chen X, Jiang Q, Guo B
PubMed: 42286377
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A new AI assisted approach aligns data standards and accelerates interoperability in biomedical research.

NPJ Digit Med. 2026 Jun 12; Epub 2026 Jun 12
Authors: Long RA, Ballard S, Shah S, Bianchi O, Jones L, Koretsky MJ, Kuznetsov N, Marsan E, Jen B, Chiang P, Mukherjee A, Blauwendraat C, Leonard H, Vitale D, Levine K, Bandres-Ciga S, Jarreau P, Brannelly P, Phatak M, Pantazis C, Screven L, Andersh K, Kapasi A, Crary JF, Gutman D, Dugger BN, Biber S, Hohman T, Faghri F, Griswold M, Sargent L, Keuren-Jensen KV, Singleton AB, Fann Y, Nalls MA, Iwaki H
PubMed: 42286188
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Biobank-based genetic characterization of neurodegenerative diseases and idiopathic normal pressure hydrocephalus: insights and lessons learned from FinnGen.

Mol Psychiatry. 2026 Jun 12; Epub 2026 Jun 12
Authors: Heikkinen S, Julkunen V, Martiskainen H, Takalo M, Solje E, Leinonen V, Haapasalo A, Lipponen A, Hiltunen M
PubMed: 42286187
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The word Dementia should be retired.

Commun Med (Lond). 2026 Jun 12;6(1)
Authors: Zuendel MT, Cabral D, Pereira AC, Reiman EM
PubMed: 42286130
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Reactive astrocytes mediate toxicity in iPSC derived dopaminergic neurons.

NPJ Parkinsons Dis. 2026 Jun 12; Epub 2026 Jun 12
Authors: Ibarra-Aizpurua N, Olano-Bringas J, Vallin B, Crompton LA, Cowley SA, Bengoa-Vergniory N, Wade-Martins R
PubMed: 42285981
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GLP-1 agonist and neuroprotection in Stroke and Parkinson's disease: A systematic review.

Dis Mon. 2026 Jun 12;:102151. Epub 2026 Jun 12
Authors: Parekh DS, Kudaiarov D, Inban P, Agrawal A, Prajjwal P, Tariq H
PubMed: 42285803
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Correction: How well do plasma Alzheimer's disease biomarkers reflect the CSF amyloid status?

J Neurol Neurosurg Psychiatry. 2026 Jun 12;97(7):e1.
Authors:
PubMed: 42285553
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Correction: First presentation with neuropsychiatric symptoms in autosomal dominant Alzheimer's disease: the Dominantly Inherited Alzheimer's Network Study.

J Neurol Neurosurg Psychiatry. 2026 Jun 12;97(7):e2.
Authors:
PubMed: 42285552
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Correction: Clinical utility of cerebrospinal fluid biomarkers in the evaluation of cognitive impairment: a systematic review and meta-analysis.

J Neurol Neurosurg Psychiatry. 2026 Jun 12;97(7):e3.
Authors:
PubMed: 42285551
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Personalized high-dose accelerated intermittent theta-burst stimulation improves cognitive function in mild Alzheimer's disease: A randomized sham-controlled trial.

Brain Stimul. 2026 Jun 12;19(4):103142. Epub 2026 Jun 12
Authors: Xu N, Xing Y, Li A, Liu S, Gao J, Liu X, Xie W, Guo N, Chen Y, Sun X, Wu J, Gong W, Wang D, Tang Y, Liu H
PubMed: 42285404
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Blood and brain tissue RNA transcriptomics reveal six potential targets of Parkinson's disease: a meta-analysis.

J Adv Res. 2026 Jun 12; Epub 2026 Jun 12
Authors: Goh SY, Theng BW, Ong HL, Zhao Y, Wang DQ, Tan EK, Lee BT, Chao Y
PubMed: 42285216
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Time to pay attention to sleep for Alzheimer's disease in women.

J Prev Alzheimers Dis. 2026 Jun 12;13(7):100624. Epub 2026 Jun 12
Authors: Bayram E
PubMed: 42285026
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Predicting accumulation and age at onset of amyloid-β from genetic risk and resilience for Alzheimer's disease.

EBioMedicine. 2026 Jun 12;129:106329. Epub 2026 Jun 12
Authors: O'Brien EK, Cox T, Fernandez S, Bourgeat P, Porter T, Goudey B, Doecke JD, Masters CL, Fripp J, Nho K, Villemagne VL, Cruchaga C, Rowe CC, Saykin AJ, Doré V, Laws SM
PubMed: 42284682
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Amyloid-Related Imaging Abnormalities in Anti-amyloid Therapy: Clinical Implications of Kinetics for Safer Use and Risk Stratification.

Clin Drug Investig. 2026 Jun 12; Epub 2026 Jun 12
Authors: Totuk O
PubMed: 42283996
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Impact of awareness of genetic status on cognitive, behavioral, and neuropsychiatric outcomes in genetic frontotemporal dementia.

J Neurol. 2026 Jun 12;273(7)
Authors: de Boer L, Reichard B, Poos JM, De Houwer JF, Swartenbroekx T, Aro OA, Rajicic A, Brouwer A, Dopper EG, Donker Kaat L, Seelaar H, Jiskoot LC
PubMed: 42283789
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Deciphering the Molecular Mechanisms of Tau K18 Liquid-Liquid Phase Separation and Its Phosphorylation/RNA-Mediated Modulation via Coarse-Grained Simulations.

J Chem Inf Model. 2026 Jun 12; Epub 2026 Jun 12
Authors: Yan Q, Liu Y, Wang T, Liu Z, Zhang Z
PubMed: 42283756
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Structures and Dynamics of Tau Assemblies from Solid-State NMR.

Acc Chem Res. 2026 Jun 12; Epub 2026 Jun 12
Authors: El Mammeri N, Hong M
PubMed: 42283695
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Editor's Note: Protective effects of antidepressant citalopram against abnormal APP processing and amyloid beta-induced mitochondrial dynamics, biogenesis, mitophagy and synaptic toxicities in Alzheimer's disease.

Hum Mol Genet. 2026 Jun 12;35(12)
Authors:
PubMed: 42283567
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Tubulin State Determines Proteopathic Fate.

Cytoskeleton (Hoboken). 2026 Jun 12; Epub 2026 Jun 12
Authors: Lucas L, Quan MD, Ferreon JC, Ferreon AC
PubMed: 42283407
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Histological and Tissue-Level Outcomes of Stem Cell Therapies in Neurodegenerative Disorders: A Systematic Review.

Clin Anat. 2026 Jun 12; Epub 2026 Jun 12
Authors: Fikry H, Saleh LA, Sadek DR
PubMed: 42283246
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Diffusion Tensor Imaging Correlates of Financial Capacity Instrument-Short Form Completion Time in Mild Cognitive Impairment.

J Neuropsychiatry Clin Neurosci. 2026 Jun 12;:appineuropsych20250087. Epub 2026 Jun 12
Authors: Stevens DA, Alm K, Bakker A, Kamath V, Manning KJ, Rebok GW, Rosenberg PB, Nowrangi MA
PubMed: 42277578
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Social and environmental determinants of dementia risk: An umbrella review.

J Alzheimers Dis. 2026 Jun 12;:13872877261456777. Epub 2026 Jun 12
Authors: Ghiasvand S, Tegegne GT, Tabatabaei-Jafari H, Mazumdar S, Ambikairajah A, Bagheri N
PubMed: 42286895
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A mechanistic framework linking the oral microbiome to Alzheimer's disease through neuroinflammation.

J Alzheimers Dis. 2026 Jun 12;:13872877261456324. Epub 2026 Jun 12
Authors: Evers MJ, Krom BP, de Jongh CA
PubMed: 42286894
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Elevated Plasma Phospho-Tau217 in Beta-Propeller Protein-Associated Neurodegeneration.

Mov Disord. 2026 Jun 12; Epub 2026 Jun 12
Authors: Lee JH, Kim YS
PubMed: 42286755
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Circadian gatekeepers of the gut-brain-immune axis: implications for neuroinflammation and neurodegeneration.

J Neuroinflammation. 2026 Jun 12; Epub 2026 Jun 12
Authors: Cheng WY, Chan PL, Chan MK, Xu J, Wong KH, Chang RC
PubMed: 42286650
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Estimation of positron emission tomography amyloid load and related biomarkers in Alzheimer's disease using evoked potential tomography EEG: development and internal validation in a cross-sectional cohort.

Alzheimers Res Ther. 2026 Jun 12;18(1)
Authors: Rauchmann BS, Hamet J, Lai J, Kafi H, Rexwinkle J, Brendel M, Franzmeier N, Kurz C, Pogarell O, Levin J, Höglinger G, Perneczky R
PubMed: 42286647
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Trends in both Alzheimer's disease and Diabetes mellitus related mortality among middle-aged and older adults in the United States, 1999 to 2023: a CDC WONDER database analysis.

BMC Neurol. 2026 Jun 12; Epub 2026 Jun 12
Authors: Javed A, Kumar S, Iftekhar M, Siddiqui HT, Khan A, Faisal F, Ali M, Sohail F, Khan MH
PubMed: 42286514
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Oral body temperature and cerebrospinal fluid pTau181 in older adults at increased risk of Alzheimer's disease.

Neurobiol Aging. 2026 Jun 12;167:25-28. Epub 2026 Jun 12
Authors: Pillet P, Tremblay-Mercier J, Picard C, Rosa-Neto P, Villeneuve S, Poirier J, Calon F, PREVENT-AD Research Group
PubMed: 42296824
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Peripheral Immune Challenge Drives Enteric α-Synuclein and Tau Pathology in LRRK2 G2019S Mice.

Aging Dis. 2026 Jun 12; Epub 2026 Jun 12
Authors: Giachino C, Bertoli F, Tirolo C, Giuliano C, Mearelli M, Jakobi M, Schneiderhan-Marra N, L'Episcopo F, Deleidi M
PubMed: 42295088
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Retraction: Aqua-soluble DDQ reduces the levels of Dr1 and Ab and inhibits abnormal interactions between Ab and Dr1 and protects Alzheimer's disease neurons from Ab- and Dr1-induced mitochondrial and synaptic toxicities.

Hum Mol Genet. 2026 Jun 12;35(12)
Authors:
PubMed: 42307453
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Linking Neurodegeneration and Age-related Macular Degeneration: Unified Pathways and Intervention Strategies.

CNS Neurol Disord Drug Targets. 2026 Jun 12; Epub 2026 Jun 12
Authors: Mukherjee S, Ray SK, Mukherjee S
PubMed: 42304926
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Therapeutic Potential of Natural Chalcones Against Alzheimer's Disease: A Mechanistic Insight.

Curr Neurovasc Res. 2026 Jun 12; Epub 2026 Jun 12
Authors: Sinha S, Gupta S, Tiwari P
PubMed: 42304917
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Nicotine Versus Non-Nicotine Constituents in Neurodegenerative Risk: Evidence from Multivariable Mendelian Randomization.

Curr Neuropharmacol. 2026 Jun 12; Epub 2026 Jun 12
Authors: Wang T, Wu M, Liang L, Pei L, Wang D
PubMed: 42304913
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Low-intensity transcranial ultrasound stimulation suppresses abnormal neural oscillations in the motor cortex by stimulating STN in α-synucleinA53T mice.

Acta Neuropathol Commun. 2026 Jun 11; Epub 2026 Jun 11
Authors: Wang Q, Dong S, Zhao Z, Ma Z, Li X, Yan J, Yuan Y
PubMed: 42277970
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Longitudinal multiphoton imaging of cerebral amyloid angiopathy in response to anti-ApoE4 immunotherapy in mice.

Mol Neurodegener. 2026 Jun 11; Epub 2026 Jun 11
Authors: Bonnar O, Saadi F, Sanchez-Mico MV, Hanlin LH, Vom Eigen KA, Mumbi N, Bacskai BJ, Greenberg SM, Holtzman DM, van Veluw SJ
PubMed: 42277961
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PAK1 expression protects cellular and behavioral defects in animal models of Parkinson' s disease.

Mol Brain. 2026 Jun 11; Epub 2026 Jun 11
Authors: Kim JE, Lee K, Kim HJ, Oh WJ, Kim HK
PubMed: 42277926
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Meningeal lymphatic dysfunction in Alzheimer's disease: molecular mechanisms, clinical implications, and future perspectives.

Mol Neurodegener. 2026 Jun 11; Epub 2026 Jun 11
Authors: Liu L, Li JH, Bai YD, Wang YJ, Bu XL
PubMed: 42277828
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Does resolvin D2 reflect cognitive impairment in older adults? A clinical and biomarker analysis.

BMC Geriatr. 2026 Jun 11; Epub 2026 Jun 11
Authors: Boz S, Dagdemir AN, Oztorun HS, Kocaismail Z, Dogrul RT, Oguz EF, Erdogan K, Yılmaz B, Efe FK, Erten R, Demirel E, Eken G, Silay K
PubMed: 42277669
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Evaluation of diagnostic concordance between algorithms for Parkinson's disease dementia.

J Parkinsons Dis. 2026 Jun 11;:1877718X261450361. Epub 2026 Jun 11
Authors: Mana M, Mana J, Stofanikova P, Uhrova T, Jech R, Bezdicek O
PubMed: 42277619
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Dynamic dual roles of gut microbial metabolites in Alzheimer's disease: Translational insights for gut-brain axis interventions.

Microbiol Res. 2026 Jun 11;311:128587. Epub 2026 Jun 11
Authors: Ye X, Jing X, Li Z, Jia L, Zhong F, Luo XG
PubMed: 42287941
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Plasma phosphorylated tau217 discordance with amyloid status in an ethnically diverse mixed memory clinic cohort.

J Neurol Sci. 2026 Jun 11;488:126057. Epub 2026 Jun 11
Authors: Kjaergaard D, Nielsen TR, Stomrud E, Bali D, Clemmensen FK, Frederiksen KS, Gleerup HS, Hasselbalch SG, Janelidze S, Hansson O, Waldemar G, Simonsen AH
PubMed: 42287769
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Midlife insulin resistance and brain beta-amyloid accumulation as predictors of change in late-life cognitive function - A 20-year follow-up study.

Neurobiol Aging. 2026 Jun 11;167:29-41. Epub 2026 Jun 11
Authors: Pietilä E, Karrasch M, Helin S, Snellman A, Viitanen M, Jula A, Rinne JO, Ekblad LL
PubMed: 42302540
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Metal-based nanoparticles' potential in Alzheimer's disease diagnosis, therapy and theranostics.

Nanoscale. 2026 Jun 11; Epub 2026 Jun 11
Authors: Khorrami S, Alifarsangi A, Mohammed LJ, Amshawee AM, Zarrabi A
PubMed: 42300608
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Development of a dynamics-enhanced facial algorithm to discriminate progressive supranuclear palsy (PSP) from Parkinson's disease (PD).

Parkinsonism Relat Disord. 2026 Jun 11;149:108377. Epub 2026 Jun 11
Authors: Ruan Z, Liu J, Guo W, Zhang Y, Yu Y, Chhetri JK, Chan P
PubMed: 42308681
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Novel Compounds as TREM2 Modulators for Treating Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, and Nasu-Hakola Disease.

ACS Med Chem Lett. 2026 Jun 11;17(6):1236-1237. Epub 2026 May 21
Authors: Sabnis RW, Sabnis AR
PubMed: 42305210
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Development of Novel 17β-HSD10 Inhibitors and Their Evaluation in an In Vitro Model of Alzheimer's Disease.

ACS Med Chem Lett. 2026 Jun 11;17(6):1347-1354. Epub 2026 May 18
Authors: Sedlacek Miskerikova M, Houfkova A, Benkova M, Andrys R, Janousek J, Soukup O, Musilek K, Benek O
PubMed: 42305190
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Microtubule Stabilization as a Therapeutic Strategy: Updated Perspectives on Alzheimer's Disease and Neurodegenerative Tauopathies.

Curr Top Med Chem. 2026 Jun 11; Epub 2026 Jun 11
Authors: Yohannan DJ, Brunden KR, Alle T
PubMed: 42304749
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Neuroinflammation in Alzheimer's Disease: New Approaches.

Curr Drug Targets. 2026 Jun 11; Epub 2026 Jun 11
Authors: Katiyar S, Yadav D, Rabbee MF
PubMed: 42304748
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Modulating the Microbiota-gut-brain Axis: A Promising Strategy for Alzheimer's Disease Prevention and Management.

CNS Neurol Disord Drug Targets. 2026 Jun 11; Epub 2026 Jun 11
Authors: Kainth R, Kushwah AS
PubMed: 42304745
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Cu2+-selective porphyrin probes with multifunctional anti-AD activities and the structural-activity insights from X-ray single crystal analysis.

Eur J Med Chem. 2026 Jun 10;316:119050. Epub 2026 Jun 10
Authors: Zhi J, Feng H, Xue Q, Pang Z, Shen R, Yang A, Kou X
PubMed: 42288030
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Curcumin-based Nanotherapeutics to Combat Neurodegenerative Disease: Drug Delivery Strategies and Therapeutic Potential.

Curr Drug Deliv. 2026 Jun 9; Epub 2026 Jun 9
Authors: Mishra Y, Mishra V
PubMed: 42283188
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Multimodal magnetic resonance imaging-based clustering identifies two imaging-defined brain phenotypes in De novo Parkinson's disease.

Neuroimage Clin. 2026 Jun 9;51:104021. Epub 2026 Jun 9
Authors: Arabi E, Tian Y, Zhu M, Gao W, Fu Y
PubMed: 42288109
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Impact of genetic variants in the longevity gene PPARGC1A and cerebrospinal fluid PPARγ levels on clinical trajectories in Parkinson's disease: Potential biomarkers for neurodegeneration and ageing.

Parkinsonism Relat Disord. 2026 Jun 9;149:108380. Epub 2026 Jun 9
Authors: Fandrich M, Schulte C, Jakobi M, Roeben B, Wurster I, Lerche S, Zimmermann S, Deuschle C, Schneiderhan-Marra N, Joos TO, Gasser T, Brockmann K, Zimmermann M
PubMed: 42288107
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A false discovery rate control method using a fully connected hidden Markov random field for neuroimaging data.

Med Image Anal. 2026 Jun 9;113:104158. Epub 2026 Jun 9
Authors: Kim T, Jia Q, de Leon MJ, Shu H, Alzheimer’s Disease Neuroimaging Initiative
PubMed: 42287840
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Synaptic regulatory flux dynamics: Stiffness and homeostatic failure in Alzheimer's disease.

Comput Methods Programs Biomed. 2026 Jun 9;285:109509. Epub 2026 Jun 9
Authors: Srimaharaj W
PubMed: 42308717
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Natural Plant Extracts Rescue Memory Deficits in Drosophila Neurodegeneration Models.

J Microbiol Biotechnol. 2026 Jun 9;36:e2603035.
Authors: Sang J, Kang Y, Lee Y
PubMed: 42305043
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Serum SIRT3 Levels and Their Relationship With Alzheimer Disease Pathological Markers in Individuals With Mild Cognitive Impairment.

Cogn Behav Neurol. 2026 Jun 9; Epub 2026 Jun 9
Authors: Du J, An Z, Niu X, Luo Y, Jing Y, Yu A
PubMed: 42312440
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Vascular Aging Across the Cardiovascular-Alzheimer's Continuum: Hemodynamics and Artificial Intelligence.

Aging Dis. 2026 Jun 8; Epub 2026 Jun 8
Authors: Zhou Z, Zhang R, Wang J, Yu Y, Wei S, Wan W
PubMed: 42295094
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Nanoscale interrogation of α-Synuclein oligomers: Bridging biophysics, interface science, and neurobiology.

Adv Colloid Interface Sci. 2026 Jun 5;356:103965. Epub 2026 Jun 5
Authors: Goncerz M, Rubiś B, Szukalska M, Totoń E, Nehra M, Malesza I, Sujka-Kordowska P, Jachimska B, Florek E, Mądry E, Kumar S, Kujawska M
PubMed: 42284999
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A Multi-Locus and Machine Learning-Based Assessment of SNCA Variants in Alzheimer's Disease.

Int J Mol Sci. 2026 Jun 5;27(11)
Authors: Segmen H, Yildiz M
PubMed: 42278664
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Strategic physicochemical tuning: amphiphilic polymers as molecular regulators of amyloid aggregation and cytotoxicity.

Chem Sci. 2026 Jun 5; Epub 2026 Jun 5
Authors: Kwak J, Park S, Kim Y, Hwang Y, Lee SJ, Kim JG, Lim MH
PubMed: 42292944
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Optimizing Antibody-Based Therapies for Alzheimer's Disease: From Clinical Limitations to Molecular Engineering Innovations.

Aging Dis. 2026 Jun 4; Epub 2026 Jun 4
Authors: Liu Q, Lin RR
PubMed: 42295086
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Novel hydroxytyrosol esters as potential anti-amyloid and neuroprotective agents for Alzheimer's disease.

RSC Med Chem. 2026 Jun 4; Epub 2026 Jun 4
Authors: Kalpaktsi I, Panara A, Mavroidi B, Niforos GG, Kalampaliki AD, Vlachogianni IC, Georgiou EA, Fragopoulou E, Tsarbopoulos A, Skaltsounis AL, Pelecanou M, Palikaras K, Gikas E, Kostakis IK
PubMed: 42306035
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Comprehensive Extraction of Shrimp Head Lipids and Peptides from Litopenaeus vannamei: Evaluation of Neuroprotective Potential and Constituent Analysis.

Foods. 2026 Jun 3;15(11)
Authors: Zhao J, Zhou L, Liu Y, Yang Z, Ban F, Zhang Y
PubMed: 42279785
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Network Meta-Analysis of Cognitive Impairment and miRNA Expression in Alzheimer's Disease Patients with Hearing Loss: A Systematic Review and Cross-Validation.

J Clin Med. 2026 Jun 3;15(11)
Authors: Wang X, Wei C
PubMed: 42279176
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Integration of Transcriptional Signatures from Brain Tissue and Plasma Extracellular Vesicles of a Preclinical Tauopathy Mouse Model.

Int J Mol Sci. 2026 Jun 3;27(11)
Authors: Lucy TT, Mamun-Or-Rashid AN, Lee DC, Lefterov I, Koldamova R, Fitz NF
PubMed: 42278575
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SGLT2 Inhibitors in Alzheimer's Disease: Biochemical Insights and Therapeutic Potential.

Int J Mol Sci. 2026 Jun 3;27(11)
Authors: Mazzeo P, Vietri M, Tecce N, Delizia A, Remondelli V, Ciaglia T, Di Dio A, Corletti L, Pizzuti CG, Pepe G, Stabile E, Correale M, Campiglia P, Miranda MR, Tecce MF, Vestuto V
PubMed: 42278574
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Beyond the Amyloid Hypothesis: Systemic Drivers, CNS-PNS Crosstalk, and the Future of Alzheimer's Disease Therapeutics.

Int J Mol Sci. 2026 Jun 2;27(11)
Authors: Velázquez de Castro-Bono A, Castro-Luna G, Guil-Guerrero JL
PubMed: 42278566
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Hippocampal, Microglial, Morphological, and Amyloid Profiles Following Thiamine Pyrophosphate Treatment in 3xTg-AD Mice.

Int J Mol Sci. 2026 Jun 2;27(11)
Authors: Pastén-Castrejón NJ, Martínez-Orozco H, Gutiérrez-Silerio GY, Hernández-Montiel HL, Maya-Arteaga JP, Poblano-Paez I, García-Solís P, Díaz-Miranda SY
PubMed: 42278547
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Multi-Dimensional Transcriptomics Reveals the Prominent Role of Neuroinflammation in Alzheimer's Disease.

Int J Mol Sci. 2026 Jun 2;27(11)
Authors: Wang X, Rong Z, Xue F
PubMed: 42278544
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Targeting Brain Cholesterol Homeostasis in Alzheimer's Disease: Mechanisms and Therapeutic Perspectives.

J Neurochem. 2026 Jun;170(6):e70492.
Authors: Ruthirakuhan M, Taha AY, Swardfager W
PubMed: 42283223
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Effects of Lysine Deacetylation Inhibition Alone or in Combination With Arimoclomol on TDP-43 Proteinopathy.

J Neurochem. 2026 Jun;170(6):e70493.
Authors: Scozzari S, Columbro SF, Favagrossa M, Tortarolo M, Cagnotto A, Salmona M, De Marco G, Bendotti C, Calvo A, Pasetto L, Bonetto V
PubMed: 42283221
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Hyperlipid-Related Alzheimer's Disease: Potential Role of CircUCK2/miR-24-3p/p38 Axis in Neuronal Damage.

Compr Physiol. 2026 Jun;16(3):e70146.
Authors: Yin WL, Peng L, Zhang JH, Huang XL, Yin WG
PubMed: 42281258
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Lecanemab Reduces Neuropsychiatric Symptoms and Related Regional Brain Amyloid Load in Early Alzheimer's Disease: A Preliminary Prospective Study.

CNS Neurosci Ther. 2026 Jun;32(6):e70974.
Authors: Chang Y, Li H, Liu X, Li X, Liu J, Song J, Fu H, Xu X, Wang Y, Wang Q, Ren N, Chen J, Deng X, Zhang X, Zuo L, Zhou B, Sun X, Li Z, Cao Y, Wu R, Jia J, Qian H, Wang R
PubMed: 42277629
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Sleep and dementia: Assessing established dementia-related factors using multivariable Mendelian randomization.

Alzheimers Dement. 2026 Jun;22(6):e71592.
Authors: Guo Y, Wang R, Sindi S, Middleton LT, Kivipelto M
PubMed: 42298291
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Provider and patient perspectives on the diagnosis and treatment of Alzheimer's disease: A global perspective from the Global Alzheimer's Leadership Series (GoALS).

Alzheimers Dement. 2026 Jun;22(6):e71536.
Authors: Amouyel P, Andrieu S, Bradshaw A, Carmona RC, Dumont M, Grinberg LT, Iwatsubo T, Hansson O, Jack CR Jr, Jicha GA, Mahinrad S, McDade E, Mummery CJ, Petersen RC, Robinson S, Schneider JA, Shellcross L, Smith AG, Snyder HM, Tapply B, Teunissen C, van der Flier WM, Vellas B, Wallon D, Williamson JD, Wilcock D, Carrillo MC
PubMed: 42298289
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The impact of cognitive behavioral therapy for insomnia on cognitive performance and amyloid beta in older adults: A randomized controlled trial.

Alzheimers Dement. 2026 Jun;22(6):e71591.
Authors: Siengsukon CF, Hand LK, Nelson E, Glaser A, Ludwig R, Russell JA, Phadnis MA, Dai J, Bruce J, Vidoni ED, Drerup M, Morris J, Burns JM
PubMed: 42298279
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Expanding the role of insulin resistance to the earliest phases of cognitive decline: Preliminary evidence.

Alzheimers Dement. 2026 Jun;22(6):e71596.
Authors: Mazzeo S, Frijo A, Corbari MV, Bortolin E, Bruschi G, Bombaci A, Pozzi FE, Astengo A, Magrì F, Pettinato A, Costa E, Filippi M, Salsone M
PubMed: 42298139
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Plasma proteomic signatures of cellular aging predict human disease.

Nat Med. 2026 Jun;32(6):2060-2072. Epub 2026 Jun 15
Authors: Ding DY, Bot VA, Chen KL, Groves JW, Pálovics R, Masuda D, Farinas A, Oh HS, Wagner V, Lu N, Global Neurodegeneration Proteomics Consortium (GNPC), Cruchaga C, Isakova A, Schott JM, Wyss-Coray T
PubMed: 42297981
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Anti-Neuroinflammatory and Neuroprotective Effects of Caffeic Acid in Experimental Models of Neurodegeneration: A Systematic Review and Meta-Analysis.

J Biochem Mol Toxicol. 2026 Jun;40(6):e70959.
Authors: Bhat R, Greeny A, Viswanatha GL, Mudgal J, Hanumanthappa S, Krishnadas N
PubMed: 42290548
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The Effect of Protein Tagging on Aggregation and Phase Separation.

J Cell Biochem. 2026 Jun;127(6):e70096.
Authors: Saito H, Sugase K
PubMed: 42290014
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WSB.APP/PS1 mice develop age-dependent cerebral amyloid angiopathy, cerebrovascular dysfunction, and white matter deficits.

Alzheimers Dement. 2026 Jun;22(6):e71476.
Authors: Marola OJ, Uyar A, Keezer KJ, Chong Chie JA, Elk KJ, Cullen AE, Eldridge K, Persohn S, Kanyinda JN, Whitesell JD, Harris JA, Salama P, Walker AE, Carter GW, Sasner M, Territo PR, Howell GR, Onos KD
PubMed: 42304169
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APOE ε4 and amyloid status moderate the associations between sleep, physical activity, and tau-PET burden in cognitively unimpaired older adults.

Alzheimers Dement. 2026 Jun;22(6):e71555.
Authors: Callow DD, Rani N, Smith JC, Soldan A, Pettigrew C, Spira AP, Albert M, Bakker A, BIOCARD Research Team
PubMed: 42304165
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Human iPSC-NSC-Derived Extracellular Vesicles Can Alleviate Alzheimer's Disease-Linked Impairments in Mitochondria, mTOR Signaling, Autophagy, and Hippocampal Neurogenesis.

Aging Cell. 2026 Jun;25(6):e70590.
Authors: Madhu LN, Attaluri S, Kotian S, Upadhya R, Somayaji Y, Rao S, Tarale P, Ganesh SV, Huard C, Kodali M, Shuai B, Rao VV, Shetty AK
PubMed: 42304162
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Brain regional susceptibility to tauopathy in individuals at risk for chronic traumatic encephalopathy.

Alzheimers Dement. 2026 Jun;22(6):e71503.
Authors: Wiegand TL, Rubinski A, Jung LB, Franzmeier N, Arciniega H, Ravanfar P, Dewenter A, Alosco ML, Tripodis Y, Su Y, Protas H, Lin AP, Pasternak O, Chen K, Coleman MJ, Bouix S, Adler CH, Balcer LJ, Bernick C, Cummings JL, Stern RA, Reiman EM, Shenton ME, Ewers M, Koerte IK, DIAGNOSE CTE Research Project
PubMed: 42304137
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Mitochondrial NADK2-dependent NADPH controls tau oligomer uptake in human neurons.

Alzheimers Dement. 2026 Jun;22(6):e71594.
Authors: Pardo E, Kim T, Wallrabe H, Zengeler KE, Sagar VK, Mingledorff G, Sun X, Periasamy A, Lukens JR, Bloom GS, Norambuena A
PubMed: 42304136
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Lumipulse Blood Biomarker Test for Diagnosis of Alzheimer Disease.

Am Fam Physician. 2026 Jun;113(6):597-598.
Authors: Hilal O, Lin KW
PubMed: 42301867
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Next-generation intranasal delivery nano-platforms for targeted brain therapy of Alzheimer's disease.

Nanomedicine (Lond). 2026 Jun;21(12):1775-1795. Epub 2026 Jun 16
Authors: Malaiya A, Kenwat R, Mamgain A, Paliwal SR, Sulakhiya K, Maiti S, Paliwal R
PubMed: 42300978
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Microsaccade Dynamics During Visual Fixation as Markers for Parkinson's Disease: A Machine Learning Approach.

Transl Vis Sci Technol. 2026 Jun 1;15(6):19.
Authors: Wang Y, Tsitsi P, Markaki I, Svenningsson P, Öqvist Seimyr G, Pansell T, Nilsson M
PubMed: 42300656
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Older Patients With Memory Complaints Often Prefer Diagnostics in Primary Care or No Further Diagnostic Evaluation.

Int J Geriatr Psychiatry. 2026 Jun;41(6):e70229.
Authors: Ronner D, Richard E, van Charante EP, van Gool WA, Schers HJ, Perry M
PubMed: 42299962
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Long-Term Perceptions of the Value of Amyloid PET Scans Among Cognitively Impaired Medicare Beneficiaries and Their Care Partners.

Int J Geriatr Psychiatry. 2026 Jun;41(6):e70226.
Authors: Bélanger E, Couch E, Carroll M, Gadbois EA, Jutkowitz E, Van Houtven CH, Wetle TT
PubMed: 42299743
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Age-Dependent Remodeling of the Sciatic Nerve Proteome in 5xFAD Mice Can Be Attenuated by Exercise or Donepezil Treatment to Maintain Neuromuscular Function.

Aging Cell. 2026 Jun;25(6):e70595.
Authors: Brisendine MH, Nieves-Esparcia DQ, Willoughby OS, Brown B, Brown JR, Braxton DS, Henry SN, McCoin CS, Thyfault JP, Morris JK, Poelzing S, Grange RW, Jarome TJ, Najt CP, Drake JC
PubMed: 42299696
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Correction to "The Myokine Irisin Represents an Indirect Pathway Linking Exercise to Hippocampal Subfields Relevant to Alzheimer's Disease and Neurogenesis".

Aging Cell. 2026 Jun;25(6):e70591.
Authors:
PubMed: 42299049
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Decoding Choroid Plexus Pathology in Alzheimer's Disease: A Longitudinal Radiomics Approach for Prodromal Identification and Risk Stratification.

CNS Neurosci Ther. 2026 Jun;32(6):e70987.
Authors: Yin F, Wang X, Chen X, Sun J, Zhang K, Dong X, Wang W, Zeng P, Li B, Nie L, Luo D, Li Y, Luo T, Alzheimer's Disease Neuroimaging Initiative
PubMed: 42298895
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The brain region that could provide a cognitive 'reservoir' in old age.

Nature. 2026 Jun;654(8120):845.
Authors:
PubMed: 42310213
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Hippocampal GFAP in aging: Associations with AD and LATE-NC pathologies and cognitive decline in older adults.

Alzheimers Dement. 2026 Jun;22(6):e71613.
Authors: Agrawal S, Yu L, Leurgans SE, Li J, Kapasi A, Agarwal P, Dage JL, Barnes LL, Bennett DA, Boyle P, Schneider JA
PubMed: 42309988
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Contributions of the Alzheimer's Disease Neuroimaging Initiative to advancing AD research: a targeted review of recent publications.

Alzheimers Dement. 2026 Jun;22(6):e71566.
Authors: Veitch DP, Miller MJ, Kanoria S, Aisen PS, Beckett LA, Green RC, Harvey DJ, Jack CR Jr, Jagust W, Lee EB, Nho K, Nosheny R, Okonkwo OC, Perrin RJ, Petersen RC, Mindt MR, Saykin AJ, Shaw LM, Toga AW, Tosun D, Landau SM, Weiner MW, Alzheimer's Disease Neuroimaging Initiative
PubMed: 42309987
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White matter hyperintensities are associated with locus coeruleus atrophy and astrocytic β2-adrenergic receptor expression.

Alzheimers Dement. 2026 Jun;22(6):e71583.
Authors: Vidal V, Farías G, Delgado C, Delano PH, Vergara RC, Orellana P, Ossandón T, Crossley NA, Gonzalez-Campo C, Naismith SL, Gonzalez-Gomez R, Coronel-Oliveros C, Ibáñez A, Wainstein G, Sanders RD, Shine JM, Medel V
PubMed: 42309986
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Vulnerability of anterior medial temporal lobe subregions to early tau-related neurodegeneration in Alzheimer's disease: Converging evidence from tau-PET and plasma p-tau217.

Alzheimers Dement. 2026 Jun;22(6):e71571.
Authors: Mundada NS, Sadeghpour N, McGrew E, Tucker HL, Nasrallah IM, Das SR, Wolk DA, Yushkevich PA, Brown CA, Wisse LE
PubMed: 42309984
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Exploring the neuroprotective, antioxidant, and anti-amyloid effects of Ganoderma lucidum compounds in Alzheimer's disease: insights from experimental and computational approaches.

J Genet Eng Biotechnol. 2026 Jun;24(2):100706. Epub 2026 May 18
Authors: Mia M, Dutta A, Hossain MM, Adhikari J, Rahman MM, Shibly AZ
PubMed: 42309609
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A novel homozygous TREM2 c.257del variant in a Chinese family with Nasu-Hakola disease: A case study and literature review.

J Int Med Res. 2026 Jun;54(6):3000605261456056. Epub 2026 Jun 18
Authors: Liu Q, Lin RR, Gao PR, Chen DF, Li HL
PubMed: 42315331
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Chemo-omic pipeline enables discovery of prion synaptotoxic pathways and inhibitory drugs.

PLoS Pathog. 2026 Jun;22(6):e1014314. Epub 2026 Jun 18
Authors: Le NT, Mercer RC, Fang C, Sundaravadivelu A, Labadorf AT, Lin W, Kwan J, Blum B, Emili A, Harris DA
PubMed: 42313800
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PROTOCOL: Barriers and Facilitators to the Adoption of Speech-Based Cognitive Screening Tools: A Protocol for Systematic Review of Qualitative Evidence.

Campbell Syst Rev. 2026 Jun;22(2):18911803261460855. Epub 2026 Jun 11
Authors: Shankar R, Sundar V, Chua KS
PubMed: 42311363
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Effects of Wheat Malt Extract on Molecular and Behavioral Markers in Aged APP/PS1 and Wild-Type Mice.

Int J Mol Sci. 2026 May 30;27(11)
Authors: Kassenova A, Svirin E, Sitdikova K, Chaprov K, Tsoy A, Munter J, Nurzhanov A, Kuznetsova M, Veremeyko T, Deykin A, Ponomarev E, Strekalova T, Askarova S
PubMed: 42278520
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ZL006 Treatment Reduces Inflammation, Oxidative Stress, and Brain Aβ1-42 Accumulation and Rescues the Loss of PSD95 Synaptic Marker in Familial Alzheimer's Disease-Associated psen1-Deficient Zebrafish Model.

Int J Mol Sci. 2026 May 30;27(11)
Authors: Ricci S, Benuzzi M, Fazzina M, Cacialli P
PubMed: 42278518
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Vitamin D3 and Dimethyl Fumarate Partially Restore Neurotrophic Signaling Without Altering Mitochondrial Integrity in the STZ-Induced Model of Sporadic AD.

Int J Mol Sci. 2026 May 29;27(11)
Authors: Piekarczyk N, Berezka P, Domkowicz K, Myślińska D, Kaczor JJ
PubMed: 42278468
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The Role of the Ketogenic Diet in Modulating Biochemical Pathophysiology in Psychiatric and Neurodegenerative Disorders.

Int J Mol Sci. 2026 May 29;27(11)
Authors: Chang YB, Baleja JD
PubMed: 42278457
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Neurodegenerative Disease: From Molecular Basis to Therapy, 3rd Edition.

Int J Mol Sci. 2026 May 29;27(11)
Authors: Ricci C
PubMed: 42278452
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Multiscale simulations reveal the driving forces underlying V337M-induced tau core fragment aggregation.

Nanoscale. 2026 May 29; Epub 2026 May 29
Authors: Xia P, Chen Y, Tang J, Guan L, Feng D, Zou Y
PubMed: 42299954
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Cannabinoids Treatment for Agitation in Alzheimer's Disease: A Systematic Review and Meta-Analysis With Bayesian and Sequential Trial Analyses.

Am J Geriatr Psychiatry. 2026 May 29; Epub 2026 May 29
Authors: da Silva AM, de Siqueira Lima DV Jr, Figueiroa Souza R, Lopes VH, Januario Campos Cardoso L, Ornelas Pinto EL, Gonçalves OR, Braga C, Cal H, Haddad DS, Vasconcelos SM, Duarte FS, Perry G, Anghinah R
PubMed: 42315374
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The inhibitors of 17β-HSD10: are they any good?

RSC Chem Biol. 2026 May 28; Epub 2026 May 28
Authors: Kwa E, Ogilvie CE, Kormos NC, Green AJ, Smith TK, Gunn-Moore FJ
PubMed: 42282265
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Air Pollution and Alzheimer's Disease: A Systematic Review and Meta-Analysis.

J Clin Med. 2026 May 28;15(11)
Authors: Baiamonte L, Tarantino D, Lodico M, Bellante G, Migliazzo C, Allegra P, Maniscalco L, Piccoli T, Vanacore N, Matranga D, Salemi G
PubMed: 42279024
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Canonical Pathways Rewiring in Alzheimer's Disease.

Int J Mol Sci. 2026 May 27;27(11)
Authors: Pinta-Castro A, Michel-Ureña G, Pérez-González AP, De Anda-Jáuregui G, Hernández-Lemus E
PubMed: 42278365
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Neuroinflammation and Secretase Regulation in Alzheimer's Disease: From Molecular Cross-Talk to Multi-Target Therapeutics.

Int J Mol Sci. 2026 May 27;27(11)
Authors: Cipriano GL, Anchesi I, Raffaele I, Astorino MF, Minuti A, Calabrò M, Crisafulli C
PubMed: 42278353
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The Role of Polyphenols on Cognitive Function and Dementia Through Gut-Microbiota-Brain Axis Modulation: A Narrative Review.

Nutrients. 2026 May 26;18(11)
Authors: Sbai O, Perrone L, Poucheret P
PubMed: 42280341
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Genome-Wide and Locus-Level Analyses Reveal Modest, Heterogeneous Genetic Sharing Between Alzheimer's Disease and Myasthenia Gravis.

Int J Mol Sci. 2026 May 26;27(11)
Authors: Adewuyi EO, Auta A, Ossai CI, Anyaegbu CC, Nguyen TT, Rahman MR, Stephan BC, Tessema GA, Nyholt DR, Pereira G
PubMed: 42278322
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Video-Supported Remote Cognitive Assessment in General Practice-A Pilot Mixed-Method Study on Usability, Acceptability and Feasibility.

Healthcare (Basel). 2026 May 25;14(11)
Authors: Holfelder A, Brill E, Guerchouche R, Tran-Duc M, Lahr J, Klöppel S
PubMed: 42278705
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Multi-Omics Integration and Causal Inference Identify HSD17B1 as a Potential Nobiletin Target Linking Neurosteroid Metabolism to Alzheimer's Disease.

Int J Mol Sci. 2026 May 25;27(11)
Authors: Gao R, Lyu C, Gu Y, Hao R, Wang C, Li X
PubMed: 42278287
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Functional Pathological Features and Molecular Markers in Alzheimer's Disease.

Int J Mol Sci. 2026 May 24;27(11)
Authors: Park MN, Kim HW, Hong JH, Kim JK, Lee SB, Baek HS, Kwak S, Kwon YJ, Park K, Jeon J, Heo NH, Lee SH, Cho J, Kim S
PubMed: 42278253
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DSP-2342, a novel 5-hydroxytryptamine 2A/7 receptor antagonist, has therapeutic potential for behavioral and psychological symptoms of dementia.

J Pharmacol Exp Ther. 2026 May 20;393(7):104949. Epub 2026 May 20
Authors: Hatakama H, Sugao K, Kassai M, Miyauchi M, Baba S, Takeda Y, Miyazaki K, Yamada K, Niu M, Natsutani I, Saito K, Nishikawa H, Kato T
PubMed: 42302487
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Efficacy of Sodium Phenylbutyrate-Taurursodiol in Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-Analysis.

Ann Indian Acad Neurol. 2026 May 1;29(3):343-352. Epub 2026 Jun 12
Authors: Jomaa AM, Khalid H, Abozait HJ, Mudassar H, Kaur R
PubMed: 42301686
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Probable Creutzfeldt-Jakob Disease With Negative Cerebrospinal Fluid (CSF) 14-3-3 Protein: Diagnostic Value of Diffusion-Weighted MRI.

Cureus. 2026 May;18(5):e108879. Epub 2026 May 15
Authors: Choukri EM, Bouymajjan A, Boulahcen Z, Ayoub C, Omari Tadlaoui S, Alaoui Rachidi S
PubMed: 42299209
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A Severe Symptomatic Case of Amyloid-Related Imaging Abnormalities After Donanemab Infusion.

Cureus. 2026 May;18(5):e109045. Epub 2026 May 17
Authors: Harikumar N, Gupta M, Al Janabi T, Mand KK
PubMed: 42311735
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Cerebral Hyperperfusion with Lecanemab in Alzheimer's Disease Assessed by Amyloid PET and Arterial Spin Labeling.

Curr Alzheimer Res. 2026 Apr 24; Epub 2026 Apr 24
Authors: Imai N, Yano H, Ikegame Y, Yasuda S, Morishima R, Okumura A, Kumagai M, Shinoda J, Izumo T
PubMed: 42299007
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Amyotrophic Lateral Sclerosis: Therapeutic Innovations and Evolving Regulatory Approaches.

CNS Neurol Disord Drug Targets. 2026 Apr 1; Epub 2026 Apr 1
Authors: Singh G, Singh S, Sarkar A, Sandhu NK
PubMed: 42299015
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Pathogenic Proteins Driving ALS Pathogenesis: Molecular Mechanisms and Translational Therapeutic Perspectives.

CNS Neurol Disord Drug Targets. 2026 Apr 1; Epub 2026 Apr 1
Authors: Kaur H, Kaur M, Sethi GK, Kaur AS, Mishra A, Sharma N
PubMed: 42299014
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The Role of Helicobacter pylori CagA Protein in Inhibiting Amyloid Protein Aggregation.

CNS Neurol Disord Drug Targets. 2026 Apr 1; Epub 2026 Apr 1
Authors: Watson A, Shahid M, Eldeeb M
PubMed: 42299012
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The role of gut microbiota in the neurobiology and treatment of Alzheimer's disease.

Gen Physiol Biophys. 2026 Mar;45(2):129-151.
Authors: Rashidi SK, Dezfouli MA, Khalili H, Kiani AK
PubMed: 42281500
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Structural covariance network alterations across the spectrum of cognitive status in Parkinson's disease.

Clin Park Relat Disord. 2026;14:100456. Epub 2026 May 26
Authors: Shibata H, Uchida Y, Sakurai K, Tanaka K, Kano Y, Matsukawa N
PubMed: 42282907
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Editorial: Biomarker discovery and validation in neurological diseases.

Front Cell Neurosci. 2026;20:1877174. Epub 2026 May 27
Authors: Singla S, Vaidya B, Martínez-Palma L, Hermann DM
PubMed: 42282855
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Propagation of α-synuclein pathology: models, mechanisms and future goals.

Mol Neurodegener Adv. 2026;2(1):26. Epub 2026 Jun 9
Authors: Zolin A, Weber SA, Xie YX, Burré J
PubMed: 42281916
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Developmental and Age-Related RAB-3 phenotypes in a C. elegans Tauopathy Model.

MicroPubl Biol. 2026;2026 Epub 2026 May 29
Authors: Anderson A, Kim Guisbert K, Borgen M
PubMed: 42294396
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Alzheimer's Research UK Research Conference 2026.

Brain Neurosci Adv. 2026;10:23982128261454415. Epub 2026 Jun 11
Authors: Simzer EM, Elliott JA, Meftah S, Sekizar S, Young LF, Catterson JH
PubMed: 42294132
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Neurodegenerative spliceosomopathies.

Front Cell Dev Biol. 2026;14:1787859. Epub 2026 May 28
Authors: Mavillonio A, Rizzini D, Detassis S, Denti MA
PubMed: 42293743
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Immunosuppression in down syndrome regression disorder: a prospective observational cohort study.

Brain Commun. 2026;8(3):fcag203. Epub 2026 Jun 2
Authors: Santoro JD, Kazerooni L, Lucas MC, Yousuf MM, Otey ST, Bouchard S, Frost KC, Nguyen L, Anadani NA, Mahmud A, Manning MA, Rachubinski AL, Kammeyer RM, Patel L, Koster LE, van Eeghen AM, Spinazzi NA, Franklin C, Quinn EA, Espinosa JM, Rafii MS
PubMed: 42293324
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Quantitative susceptibility mapping reveals widespread brain iron abnormalities in sporadic patients with early-stage amyotrophic lateral sclerosis.

Brain Commun. 2026;8(3):fcag190. Epub 2026 May 26
Authors: Ma M, Zhao B, Gao N, Sun X, Shao K, Lin P, Li W, Zhao Y, Yu D, Yan C, Liu S, Yun Y
PubMed: 42293321
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Thyroid hormones and energy metabolism in amyotrophic lateral sclerosis.

Brain Commun. 2026;8(3):fcag198. Epub 2026 Jun 4
Authors: Novikova L, Lang C, Tumani H, Klose V, Kassubek J, Dreyhaupt J, Dupuis L, Wabitsch M, Ludolph A
PubMed: 42293320
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Music processing in behavioural variant frontotemporal dementia and Alzheimer's disease: a functional MRI study.

Brain Commun. 2026;8(3):fcag196. Epub 2026 Jun 1
Authors: van 't Hooft JJ, van der Zwaag W, Wink AM, Barkhof F, Schaefer RS, Warren JD, Pijnenburg YA, Tijms BM
PubMed: 42293318
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Mitochondrial dysfunction in Alzheimer's disease: connecting pathophysiology with neuroimaging.

Front Aging Neurosci. 2026;18:1748227. Epub 2026 May 29
Authors: Hu J, Lai J, Zhang B, Jiang X, Ma H, Liu Y
PubMed: 42293151
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SVIP in plasma: a candidate blood-based biomarker for early detection of amnestic mild cognitive impairment.

Front Aging Neurosci. 2026;18:1781331. Epub 2026 May 29
Authors: Lu G, Shan H, Yin Y, Chen L, Yu K, Wei Z, Chen H, Hu L, Qi Y, Wu T, Tao S, Fan X, Cheng G
PubMed: 42293149
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Propranolol reinstates mitochondrial dynamics and synaptic memory pathways through CaMKII/CREB-BDNF/ PKMζ cascades in an AD-like rat model.

Front Aging Neurosci. 2026;18:1729046. Epub 2026 May 29
Authors: Pinky, Neha, Kaushik M, Tiwari P, El-Tanani M, Rabbani SA, Parvez S
PubMed: 42293147
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Multiple system atrophy: integrating clinical phenotypes and multimodal biomarkers for early diagnosis.

Front Aging Neurosci. 2026;18:1801658. Epub 2026 May 29
Authors: Wilkens I, Hopfner F
PubMed: 42293144
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Gerobiotics and neuroprotection: effects on the gut-brain axis in age-related neurodegenerative diseases.

Front Aging Neurosci. 2026;18:1814234. Epub 2026 May 28
Authors: Kocaadam-Bozkurt B, Aslan S, Bozkurt O, Bodur M, Agagündüz D, Budán F
PubMed: 42293143
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Regional dopaminergic dysfunction patterns discriminate Parkinson's disease from multiple system atrophy parkinsonian subtype.

Clin Park Relat Disord. 2026;14:100451. Epub 2026 May 23
Authors: Xu D, Jia C, Zhang T, Ren C, Zhu W, Wang H, Huo L
PubMed: 42292967
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FUSION-AD: interpretable AI framework for risk assessment and subgroup discovery in Alzheimer's disease.

Front Neuroinform. 2026;20:1799307. Epub 2026 May 28
Authors: Iqbal A, Arif S, Husnain G, Ayouni S
PubMed: 42292927
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Pharmacology of nivegacetor (RG6289), a potent and selective gamma secretase modulator in clinical development for the treatment of Alzheimer's disease.

Front Pharmacol. 2026;17:1783414. Epub 2026 May 28
Authors: Lindemann L, Lambotte J, Rothe J, Messer J, Diener C, Pichereau S, Cantrill C, Mueggler T, Honer M, Beck J, Steinbrecher T, Tortelli R, Gerlach I, Ratni H, Rodriguez Sarmiento RM, Baumann K
PubMed: 42292846
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Mitochondrial dysfunction in Alzheimer's disease: targeting the powerhouse with nanomedicine.

Front Pharmacol. 2026;17:1755126. Epub 2026 May 29
Authors: Kang C, Zhou X, Li B, Li J
PubMed: 42292813
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Microglial metabolic reprogramming drives the therapeutic effects of bavachinin on brain network function and memory in Alzheimer's disease.

Front Pharmacol. 2026;17:1839602. Epub 2026 May 28
Authors: Zou Y, Lin Y, Zhang C, Li Y, Chen X, Ma X, Chen K, Liang B, Liang P
PubMed: 42292809
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Editorial: Unraveling protein misfolding and innate immunity in neurodegenerative diseases.

Front Immunol. 2026;17:1873694. Epub 2026 May 28
Authors: Fang Q, Hong Y, Zhu B
PubMed: 42292439
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Neuroinflammation in Alzheimer's disease: glial crosstalk, pathological modulation, and therapeutic implications.

Front Immunol. 2026;17:1783786. Epub 2026 May 29
Authors: Li E, Zhang P, Feng W
PubMed: 42292389
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Mechanisms of action and advances in application of music therapy in improving cognitive impairment based on the theory of neuroplasticity.

Front Neurosci. 2026;20:1828930. Epub 2026 May 28
Authors: Zeng ZT, Tang JX, Wang SR, Lei LZ, Xing ZY, Wang JM, Wu J
PubMed: 42292338
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Vascular endothelial growth factor receptor-1 (VEGFR-1) knock-down is protective against hypoxia, Aβ1-42 oligomer and Aβ1-42 fibril -induced neuronal cell death: implications in AD pathogenesis.

Front Neurosci. 2026;20:1799391. Epub 2026 May 29
Authors: Mukhopadhyay D, Das P, Angom RS, Dutta S, Li Z, Castanedes-Casey M, Kulkarni T, Chakravarty T, Wang E, Dickson D, Rachamala HK
PubMed: 42292330
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Plant-Derived Exosome-Like Nanoparticles in Neurodegenerative Diseases: From Dual Bioactive-Delivery Roles to Translational Challenges.

Int J Nanomedicine. 2026;21:608292. Epub 2026 Jun 9
Authors: Sun Y, Xu Z, Cui L, Guo J, Zhang X, Xiao Y
PubMed: 42292037
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STIP1/HOP promotes the formation of cytotoxic α-synuclein oligomers.

Mol Neurodegener Adv. 2026;2(1):27. Epub 2026 Apr 24
Authors: Rutledge BS, Wilson CJ, Lau RM, Jurado-Coronel JC, Del Cid-Pellitero E, Karttunen M, Durcan TM, Fon EA, Prado MA, Legleiter J, Duennwald ML, Choy WY
PubMed: 42291828
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Glymphatic clearance as revealed by diffusion tensor imaging along the perivascular space (DTI-ALPS) is associated with Alzheimer's disease neuropathology and periodic rsEEG alpha rhythms in mild cognitive impairment participants.

Alzheimers Dement (Amst). 2026;18(2):e70384. Epub 2026 Jun 11
Authors: Lopez S, Del Percio C, Lizio R, Noce G, Carpi M, Arnaldi D, Famà F, Pardini M, Massa F, Marinozzi F, Bini F, Treves G, Soricelli A, Salvatore M, Giubilei F, Ziccardi L, Güntekin B, Yener G, Ferri R, Lanuzza B, Stocchi F, Vacca L, Coletti C, Infarinato F, Romano P, Marizzoni M, Frisoni GB, Barone P, Cappiello A, Cuoco S, Bonanni L, D'Anselmo A, Antonini A, Fiorenzato E, Cauzzo S, Biundo R, D'Antonio F, De Pandis MF, Marziali S, Bruno G, Carducci F, Babiloni C
PubMed: 42291616
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Enlarged perivascular spaces in subcortical white matter are linked to amyloid-tau depositions and cognitive decline: Data from a memory clinic in Thailand.

Alzheimers Dement (Amst). 2026;18(2):e70399. Epub 2026 Jun 11
Authors: Booncharoen K, Thanapornsangsuth P, Pongpitakmetha T, Sarutikriangkri Y, Likitjaroen Y, Thanprasertsuk S
PubMed: 42291615
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The role of YKL-40 in Alzheimer's disease pathology and drug targeting.

PeerJ. 2026;14:e21361. Epub 2026 Jun 8
Authors: Sha Y, Fu H, Lu K, Wang G, Wang Y
PubMed: 42291413
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Intensive multidisciplinary rehabilitation modulates serum α-synuclein and miRNA expression in Parkinson's disease: preliminary results of a randomized study.

Front Cell Neurosci. 2026;20:1760593. Epub 2026 May 28
Authors: Agostini S, Meloni M, Mancuso R, Nuzzi R, Ferraro G, Salvatore A, Arcuri P, Castagna A, Navarro J, Saibene FL, Clerici M
PubMed: 42290958
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Role of Rehabilitation in the Management of Alzheimer's Disease and Related Dementias: Healthcare Provider Perspectives.

J Prim Care Community Health. 2026;17:21501319261461254. Epub 2026 Jun 14
Authors: Putri CA, Faieta J, Ebuenyi ID
PubMed: 42290126
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Analysis signals of disproportionate reporting associated with donanemab: A retrospective pharmacovigilance study using the FAERS database.

Sci Prog. 2026;109(2):368504261461675. Epub 2026 Jun 16
Authors: Zhang Y, Gong Q, Yu J, Zhang L, Hu Y
PubMed: 42302007
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Optimized detection of caspase-6 activation in a murine inflammation model to inform neurodegenerative disease therapies.

PLoS One. 2026;21(6):e0351312. Epub 2026 Jun 17
Authors: Sagarbarria I, Seo J, Smith AJ, Vazey EM, Tremblay KD, Mager J, Hardy JA
PubMed: 42308231
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APOE3-Christchurch variant enhances neurovascular support functions of iPSC-derived mesenchymal stromal cells.

Front Mol Biosci. 2026;13:1778856. Epub 2026 Jun 1
Authors: Rodriguez Martinez PJ, Yslas AR, Inoue Y, Parsons TM, Baker SK, Lu W, Raulin AC, Kanekiyo T
PubMed: 42306774
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Equity and budget challenges associated with the employment of anti-amyloid monoclonal antibodies for early Alzheimer's Disease in Italy: A scenario analysis.

JAR Life. 2026;15:100076. Epub 2026 Jun 4
Authors: Giorelli M, Fazio PD, Dimatteo T
PubMed: 42306480
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Therapeutic Potential of Naive Hair Follicle Stem Cells in Alzheimer's Disease: A Comprehensive Evaluation of Neuroprotection and Neurogenesis.

Neuropsychiatr Dis Treat. 2026;22:601127. Epub 2026 Jun 11
Authors: Liu L, Yang D, Fu J
PubMed: 42306175
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Imaging biomarkers of glymphatic system dysfunction in Alzheimer's disease: a systematic review and meta-analysis with a focus on DTI-ALPS index.

Front Aging Neurosci. 2026;18:1749316. Epub 2026 Jun 1
Authors: Liao Z, Chen R, Yang X, Shen K, Zeng J, Zhou H, Fang C, Liu Y, Chen C
PubMed: 42306139
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Overcoming the diagnostic gap in mild cognitive impairment in Parkinson's disease: a pilot study employing a machine learning-/augmented reality-based digital biomarker.

Front Aging Neurosci. 2026;18:1839000. Epub 2026 Jun 1
Authors: Poplawska-Domaszewicz K, Streel E, Brek A, Miśko N, Kosińska E, Metta V, Odin P, Antonini A, Biundo R, Fiorenzato E, Wu K, Chopra S, Haridas S, Tarnanas I, Griffin N, Brugada-Ramentol V, Iulita MF, Jones M, Michalak S, Kozubski W, Ray Chaudhuri K
PubMed: 42306138
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Analysis of structural alterations in olfactory-related brain regions in patients with cognitive impairment and the correlation with olfactory function.

Front Aging Neurosci. 2026;18:1778960. Epub 2026 Jun 1
Authors: Han X, Cao X, Liu L, Wang Z, Gao D, Lv H, Yang H, Wang Y, Cui C, Li S, Yang Q, Cui J, Zhang Z, Wang H, Cheng S, Song B, Geng Z
PubMed: 42306137
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Advances in AI-based diagnosis of Alzheimer's disease using MRI: a comprehensive survey.

Front Med (Lausanne). 2026;13:1767090. Epub 2026 Jun 1
Authors: Alyaqoobi HI, Lopez-Guede JM, Dara OA, Ramos-Hernanz JA, Aramendia I, Teso-Fz-Betoño D
PubMed: 42305954
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Neuropsychiatric symptoms and social cognition in frontotemporal dementia and Alzheimer's disease.

Dement Neuropsychol. 2026;20:e20250409. Epub 2026 Jun 15
Authors: Saraiva LA, Resende EP, Mariano LI, Paula DS, Caramelli P, Salgado JV, de Souza LC
PubMed: 42305952
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National and international models of involving people with lived experience in dementia policy, advocacy and research.

Front Dement. 2026;5:1816031. Epub 2026 Jun 2
Authors: Snowball E, Casey R, Myers Barnett K, Campill S, Eliassen JR, Tur Eliassen M, Anderton B, Stockwell-Lance C, Warbelow M, Bacsu JD, Lanza E, Bethell J
PubMed: 42311857
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Transcriptome-informed metabolic modeling reveals astrocyte-specific vulnerabilities in mild cognitive impairment and Alzheimer's disease progression.

Front Bioinform. 2026;6:1816121. Epub 2026 Jun 2
Authors: Angarita-Rodríguez A, Vargas-López V, Pinzón A, Sandoval-Hernandez A, Kang K, Li L, Papin J, Puentes-Rozo P, Aristizábal AF, González J
PubMed: 42311824
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Prevalence of Lewy body pathology and phenotypic associations in patients with mild cognitive impairment: Evidence from the Interceptor study.

Alzheimers Dement (Amst). 2026;18(2):e70382. Epub 2026 Jun 15
Authors: Baiardi S, Caldera S, Capellari S, Magliocchetti F, Mammana A, Zenesini C, Cappa S, Caraglia N, Cotelli M, Marra C, Miraglia F, Perani D, Redolfi A, Spadin P, Tagliavini F, Vanacore N, Vecchio F, Rossini PM, Parchi P
PubMed: 42311702
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Copper isotope shifts in biofluids track Alzheimer's pathology.

Alzheimers Dement (Amst). 2026;18(2):e70316. Epub 2026 Jun 15
Authors: Lahoud E, Moynier F, Mahan B, Luu TH, Rigoussen D, Le Borgne M, Paquet C, Fowler C, Bush AI
PubMed: 42311701
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Optimizing scalable approaches for early detection of cognitive impairment in primary care.

Alzheimers Dement (Amst). 2026;18(2):e70393. Epub 2026 Jun 15
Authors: Owora AH, Summanwar D, Kulshreshtha A, Miled ZB, Dexter PR, Jiang B, Shah Y, Puster E, Coppedge K, Disla S, Galvin JE, Fowler NR, Boustani M
PubMed: 42311700
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Age-dependent vulnerability to spatial memory interference in APP/PS1 mice.

Front Aging Neurosci. 2026;18:1794153. Epub 2026 Jun 2
Authors: Mitrovic Tartanoglu D, Tartanoglu CH, Sonnenberg C, Sabariego M, Haberl MG, Viana da Silva S
PubMed: 42311499
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APOE4 accelerates menopause-associated brain metabolic shift and disrupts bioenergetic adaptation.

Front Aging Neurosci. 2026;18:1796680. Epub 2026 Jun 2
Authors: Wang T, Shang Y, McLean JW, Yin F, Brinton RD
PubMed: 42311497
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Serum BP180 and BP230 autoantibodies in Alzheimer's disease: diagnostic and cognitive associations in a retrospective study.

Front Aging Neurosci. 2026;18:1757497. Epub 2026 Jun 2
Authors: Jin S, Yu J, Liu HL, Wang C, Zheng FM
PubMed: 42311495
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GLP-1 Receptor Agonists in Neurological Disorders: From Mechanisms to Clinical Translation.

Drug Des Devel Ther. 2026;20:613616. Epub 2026 Jun 12
Authors: Li P, Gao Y, Liu W
PubMed: 42311464
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Affective and cognitive theory of mind and associated brain functional alterations in frontotemporal dementia.

Brain Commun. 2026;8(3):fcag216. Epub 2026 Jun 6
Authors: Tripodi C, Canu E, Marangon A, Castelnovo V, Basaia S, Spinelli EG, Cecchetti G, Ghirelli A, Pisano S, Rugarli G, Caso F, Magnani G, Caroppo P, Prioni S, Villa C, Tremolizzo L, Appollonio I, Verde F, Ticozzi N, Silani V, Filippi M, Agosta F
PubMed: 42311451
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Deep cervical lymphaticovenous anastomosis for Alzheimer's disease: theoretical foundations, regulatory suspension, and translational challenges.

Front Aging. 2026;7:1849207. Epub 2026 Jun 2
Authors: Li G, Jiao S, Zhou Y, Cheng X
PubMed: 42311340
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Research should be conducted with us, not on us: Perspectives on Alzheimer's disease clinical trials for persons with Down syndrome.

Alzheimers Dement Behav Socioecon Aging. 2025 Dec;1(4) Epub 2025 Oct 7
Authors: Foye G, Foye E, Walter S, Ptomey LT
PubMed: 42281759
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