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<?xml-stylesheet type="text/xsl" media="screen" href="/~d/styles/rss2enclosuresfull.xsl"?><?xml-stylesheet type="text/css" media="screen" href="http://feeds.feedburner.com/~d/styles/itemcontent.css"?><rss xmlns:media="http://search.yahoo.com/mrss/" xmlns:itunes="http://www.itunes.com/dtds/podcast-1.0.dtd" xmlns:feedburner="http://rssnamespace.org/feedburner/ext/1.0" version="2.0"><channel><title>Abeta</title><link>http://betaamyloid.blogspot.com/</link><atom10:link xmlns:atom10="http://www.w3.org/2005/Atom" rel="self" type="application/rss+xml" href="http://feeds.feedburner.com/AmyloidEtal" /><description></description><language>en</language><managingEditor>noreply@blogger.com (Sanjay Bhardwaj)</managingEditor><lastBuildDate>Mon, 19 Oct 2009 05:50:40 PDT</lastBuildDate><generator>Blogger http://www.blogger.com</generator><openSearch:totalResults xmlns:openSearch="http://a9.com/-/spec/opensearch/1.1/">35</openSearch:totalResults><openSearch:startIndex xmlns:openSearch="http://a9.com/-/spec/opensearch/1.1/">1</openSearch:startIndex><openSearch:itemsPerPage xmlns:openSearch="http://a9.com/-/spec/opensearch/1.1/">25</openSearch:itemsPerPage><feedburner:info uri="amyloidetal" /><atom10:link xmlns:atom10="http://www.w3.org/2005/Atom" rel="hub" href="http://pubsubhubbub.appspot.com/" /><itunes:owner><itunes:email>amyloidorg@gmail.com</itunes:email></itunes:owner><itunes:explicit>no</itunes:explicit><itunes:subtitle>You Daily Dose on Amyloid Peptides</itunes:subtitle><feedburner:emailServiceId>AmyloidEtal</feedburner:emailServiceId><feedburner:feedburnerHostname>http://feedburner.google.com</feedburner:feedburnerHostname><item><title>amyloid inhibitors</title><link>http://feedproxy.google.com/~r/AmyloidEtal/~3/g3qYm_xxWQQ/amyloid-inhibitors.html</link><author>amyloidorg@gmail.com</author><pubDate>Thu, 15 Oct 2009 07:47:48 PDT</pubDate><guid isPermaLink="false">tag:blogger.com,1999:blog-6662563293158062075.post-8583813960019932842</guid><description>&lt;meta http-equiv="Content-Language" content="en-us"&gt;&lt;br /&gt;
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&lt;meta content= Abeta Blog, an informative website, is a sincere efforts of Scientists for the Scientists by providing a informative platform for Beta Amyloid Research Publications. Beta Amyloid blog keeps up details of Alzheimer Research Labs, Alzheimer Research conferences around the world.' name='description'/&gt;&lt;br /&gt;
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&lt;div class="MsoNormal"&gt;&lt;b&gt;&lt;u&gt;Amyloid Inhibitors&lt;o:p&gt;&lt;/o:p&gt;&lt;/u&gt;&lt;/b&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Raymond SB, Kumar AT, Boas DA, Bacskai BJ. &lt;b&gt;Optimal parameters for near infrared fluorescence imaging of amyloid plaques in Alzheimer's disease mouse models.&lt;/b&gt; &lt;i&gt;Phys Med Biol&lt;/i&gt;. 2009 Oct 21;54(20):6201-16. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19794239" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Bedrood S, Jayasinghe S, Sieburth D, Chen M, Erbel S, Butler PC, Langen R, Ritzel RA. &lt;b&gt;Annexin A5 Directly Interacts with Amyloidogenic Proteins and Reduces Their Toxicity.&lt;/b&gt; &lt;i&gt;Biochemistry&lt;/i&gt;. 2009 Oct 8; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19810772" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Hedden T, Van Dijk KR, Becker JA, Mehta A, Sperling RA, Johnson KA, Buckner RL. &lt;b&gt;Disruption of functional connectivity in clinically normal older adults harboring amyloid burden.&lt;/b&gt; &lt;i&gt;J Neurosci&lt;/i&gt;. 2009 Oct 7;29(40):12686-94. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19812343" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Cousins SL, Hoey SE, Stephenson FA, Perkinton MS. &lt;b&gt;AMYLOID PRECURSOR PROTEIN 695 ASSOCIATES WITH ASSEMBLED NR2A-AND NR2B-CONTAINING NMDA RECEPTORS TO RESULT IN THE ENHANCEMENT OF THEIR CELL SURFACE DELIVERY.&lt;/b&gt; &lt;i&gt;J Neurochem&lt;/i&gt;. 2009 Oct 7; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19811606" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Hoffner G, André W, Vanhoutteghem A, Souès S, Djian P. &lt;b&gt;Transglutaminase-Catalyzed Cross linking in Neurological Disease: from Experimental Evidence to Therapeutic Inhibition.&lt;/b&gt; &lt;i&gt;CNS Neurol Disord Drug Targets&lt;/i&gt;. 2009 Oct 7; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19811443" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Meyer-Luehmann M, Mielke M, Spires-Jones TL, Stoothoff W, Jones P, Bacskai BJ, Hyman BT. &lt;b&gt;A reporter of local dendritic translocation shows plaque- related loss of neural system function in APP-transgenic mice.&lt;/b&gt; &lt;i&gt;J Neurosci&lt;/i&gt;. 2009 Oct 7;29(40):12636-40. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19812338" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Yang TT, Hsu CT, Kuo YM. &lt;b&gt;Cell-derived soluble oligomers of human amyloid-beta peptides disturb cellular homeostasis and induce apoptosis in primary hippocampal neurons.&lt;/b&gt; &lt;i&gt;J Neural Transm&lt;/i&gt;. 2009 Oct 7; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19809865" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Atamna H. &lt;b&gt;Amino acids variations in Amyloid-beta peptides, mitochondrial dysfunction, and new therapies for Alzheimer's disease.&lt;/b&gt; &lt;i&gt;J Bioenerg Biomembr&lt;/i&gt;. 2009 Oct 6; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19806442" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Wille H, Bian W, McDonald M, Kendall A, Colby DW, Bloch L, Ollesch J, Borovinskiy AL, Cohen FE, Prusiner SB, Stubbs G. &lt;b&gt;Natural and synthetic prion structure from X-ray fiber diffraction.&lt;/b&gt; &lt;i&gt;Proc Natl Acad Sci U S A&lt;/i&gt;. 2009 Oct 6;106(40):16990-5. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19805070" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Price KA, Caragounis A, Paterson BM, Filiz G, Volitakis I, Masters CL, Barnham KJ, Donnelly PS, Crouch PJ, White AR. &lt;b&gt;Sustained Activation of Glial Cell Epidermal Growth Factor Receptor by Bis(thiosemicarbazonato) Metal Complexes Is Associated with Inhibition of Protein Tyrosine Phosphatase Activity.&lt;/b&gt; &lt;i&gt;J Med Chem&lt;/i&gt;. 2009 Oct 6; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19807095" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Ran C, Xu X, Raymond SB, Ferrara BJ, Neal K, Bacskai BJ, Medarova Z, Moore A. &lt;b&gt;Design, Synthesis, and Testing of Difluoroboron-Derivatized Curcumins as Near-Infrared Probes for in Vivo Detection of Amyloid-beta Deposits.&lt;/b&gt; &lt;i&gt;J Am Chem Soc&lt;/i&gt;. 2009 Oct 6; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19807070" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
Davis CH, Berkowitz ML. &lt;b&gt;Structure of the Amyloid-beta (1-42) Monomer Absorbed To Model Phospholipid Bilayers: A Molecular Dynamics Study.&lt;/b&gt; &lt;i&gt;J Phys Chem B&lt;/i&gt;. 2009 Oct 6; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19807060" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Serrano F, Chang A, Hernandez C, Pautler RG, Sweatt JD, Klann E. &lt;b&gt;NADPH oxidase mediates beta-amyloid peptide-induced activation of ERK in hippocampal organotypic cultures.&lt;/b&gt; &lt;i&gt;Mol Brain&lt;/i&gt;. 2009 Oct 5;2(1):31. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19804648" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Takeda S, Sato N, Takeuchi D, Kurinami H, Shinohara M, Niisato K, Kano M, Ogihara T, Rakugi H, Morishita R. &lt;b&gt;Angiotensin Receptor Blocker Prevented {beta}-Amyloid-Induced Cognitive Impairment Associated With Recovery of Neurovascular Coupling.&lt;/b&gt; &lt;i&gt;Hypertension&lt;/i&gt;. 2009 Oct 5; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19805638" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Yang X, Sheng W, He Y, Cui J, Haidekker MA, Sun GY, Lee JC. &lt;b&gt;Secretory phospholipase A2 Type III enhances {alpha}-secretase-dependent amyloid precursor protein processing through alterations in membrane fluidity.&lt;/b&gt; &lt;i&gt;J Lipid Res&lt;/i&gt;. 2009 Oct 5; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19805624" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Jäger S, Leuchtenberger S, Martin A, Czirr E, Wesselowski J, Dieckmann M, Waldron E, Korth C, Koo EH, Heneka M, Weggen S, Pietrzik CU. &lt;b&gt;alpha-secretase mediated conversion of the Amyloid Precursor Protein derived membrane stub C99 to C83 limits Abeta generation.&lt;/b&gt; &lt;i&gt;J Neurochem&lt;/i&gt;. 2009 Oct 5; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19804379" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Ye JT, Pi RB, Mao XX, Chen XH, Qin J, Xu SW, Liu PQ. &lt;b&gt;Alterations in mRNA expression of BACE1, cathepsin B, and glutaminyl cyclase in mice ischemic brain.&lt;/b&gt; &lt;i&gt;Neuroreport&lt;/i&gt;. 2009 Oct 3; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19809370" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Surguchev A, Surguchov A. &lt;b&gt;Conformational diseases: looking into the eyes.&lt;/b&gt; &lt;i&gt;Brain Res Bull&lt;/i&gt;. 2009 Oct 3; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19808079" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Mancuso M, Calsolaro V, Orsucci D, Siciliano G, Murri L. &lt;b&gt;Is there a primary role of the mitochondrial genome in Alzheimer's disease?&lt;/b&gt; &lt;i&gt;J Bioenerg Biomembr&lt;/i&gt;. 2009 Oct 2; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19798559" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
Ferrer I. &lt;b&gt;Altered mitochondria, energy metabolism, voltage-dependent anion channel, and lipid rafts converge to exhaust neurons in Alzheimer's disease.&lt;/b&gt; &lt;i&gt;J Bioenerg Biomembr&lt;/i&gt;. 2009 Oct 2; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19798558" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Alikhani N, Ankarcrona M, Glaser E. &lt;b&gt;Mitochondria and Alzheimer's disease: amyloid-beta peptide uptake and degradation by the presequence protease, hPreP.&lt;/b&gt; &lt;i&gt;J Bioenerg Biomembr&lt;/i&gt;. 2009 Oct 2; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19798557" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Taniguchi A. &lt;b&gt;[Development of click peptide: stimuli-responsive precursor producing Alzheimer's disease-related amyloid beta peptide]&lt;/b&gt; &lt;i&gt;Yakugaku Zasshi&lt;/i&gt;. 2009 Oct;129(10):1227-32. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19797878" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Nakaya T, Kawai T, Suzuki T. &lt;b&gt;Metabolic stabilization of p53 by FE65 in the nuclear matrix of osmotically stressed cells.&lt;/b&gt; &lt;i&gt;FEBS J&lt;/i&gt;. 2009 Oct 1; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19796171" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Niebroj-Dobosz I, Janik P, Sokolowska B, Kwiecinski H. &lt;b&gt;Matrix metalloproteinases and their tissue inhibitors in serum and cerebrospinal fluid of patients with amyotrophic lateral sclerosis.&lt;/b&gt; &lt;i&gt;Eur J Neurol&lt;/i&gt;. 2009 Oct 1; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19796283" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Ono M. &lt;b&gt;Development of positron-emission tomography/single-photon emission computed tomography imaging probes for in vivo detection of beta-amyloid plaques in Alzheimer's brains.&lt;/b&gt; &lt;i&gt;Chem Pharm Bull (Tokyo)&lt;/i&gt;. 2009 Oct;57(10):1029-39. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19801854" target="_blank"&gt;Amyloid Inhibitors&lt;/a&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Reference: Pub Med Abstracts&lt;br /&gt;
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&lt;div class="blogger-post-footer"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6662563293158062075-8583813960019932842?l=betaamyloid.blogspot.com'/&gt;&lt;/div&gt;&lt;img src="http://feeds.feedburner.com/~r/AmyloidEtal/~4/g3qYm_xxWQQ" height="1" width="1"/&gt;</description><app:edited xmlns:app="http://www.w3.org/2007/app">2009-10-15T07:47:48.524-07:00</app:edited><thr:total xmlns:thr="http://purl.org/syndication/thread/1.0">0</thr:total><feedburner:origLink>http://betaamyloid.blogspot.com/2009/10/amyloid-inhibitors.html</feedburner:origLink></item><item><title>Amyloid Beta Fibrils</title><link>http://feedproxy.google.com/~r/AmyloidEtal/~3/6l_tOYXdfcs/amyloid-beta-fibrils.html</link><author>amyloidorg@gmail.com</author><pubDate>Thu, 15 Oct 2009 04:47:42 PDT</pubDate><guid isPermaLink="false">tag:blogger.com,1999:blog-6662563293158062075.post-5710681383426751800</guid><description>&lt;meta http-equiv="Content-Language" content="en-us"&gt;&lt;br /&gt;
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&lt;meta content= Beta Amyloid.org, an informative website, is a sincere efforts of Scientists for the Scientists by providing a informative platform for Beta Amyloid Research Publications. Beta Amyloid blog keeps up details of Alzheimer Research Labs, Alzheimer Research conferences around the world.' name='description'/&gt;&lt;br /&gt;
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&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Bedrood S, Jayasinghe S, Sieburth D, Chen M, Erbel S, Butler PC, Langen R, Ritzel RA. &lt;b&gt;Annexin A5 Directly Interacts with Amyloidogenic Proteins and Reduces Their Toxicity.&lt;/b&gt; &lt;i&gt;Biochemistry&lt;/i&gt;. 2009 Oct 8; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19810772" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;Meyer-Luehmann M, Mielke M, Spires-Jones TL, Stoothoff W, Jones P, Bacskai BJ, Hyman BT. &lt;b&gt;A reporter of local dendritic translocation shows plaque- related loss of neural system function in APP-transgenic mice.&lt;/b&gt; &lt;i&gt;J Neurosci&lt;/i&gt;. 2009 Oct 7;29(40):12636-40. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19812338" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;br /&gt;
&lt;/div&gt;&lt;div class="MsoNormal"&gt;&lt;br /&gt;
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&lt;div class="blogger-post-footer"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6662563293158062075-5710681383426751800?l=betaamyloid.blogspot.com'/&gt;&lt;/div&gt;&lt;img src="http://feeds.feedburner.com/~r/AmyloidEtal/~4/6l_tOYXdfcs" height="1" width="1"/&gt;</description><app:edited xmlns:app="http://www.w3.org/2007/app">2009-10-15T04:47:42.412-07:00</app:edited><thr:total xmlns:thr="http://purl.org/syndication/thread/1.0">0</thr:total><feedburner:origLink>http://betaamyloid.blogspot.com/2009/10/amyloid-beta-fibrils.html</feedburner:origLink></item><item><title>Beta Amyloid 1 40: Research Paper Beta Amyloid 1 40</title><link>http://feedproxy.google.com/~r/AmyloidEtal/~3/O4iNieoVCA4/beta-amyloid-1-40-research-paper-beta.html</link><author>amyloidorg@gmail.com</author><pubDate>Mon, 12 Oct 2009 22:59:14 PDT</pubDate><guid isPermaLink="false">tag:blogger.com,1999:blog-6662563293158062075.post-1454339271100245447</guid><description>&lt;meta equiv="Content-Type" content="text/html; 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font-family: Arial;"&gt;Beta Amyloid 1 40: Research Paper Beta Amyloid 1 40&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/u&gt;&lt;/b&gt;&lt;/p&gt;    &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;Kumar A, Dogra S, Prakash A. &lt;b&gt;Protective effect of curcumin (Curcuma longa), against aluminium toxicity: Possible behavioral and biochemical alterations in rats.&lt;/b&gt; &lt;i&gt;Behav Brain Res&lt;/i&gt;. 2009 Dec 28;205(2):384-90. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19616038" target="_blank"&gt;PubMed Abstract&lt;/a&gt; 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&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;div class="blogger-post-footer"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6662563293158062075-1454339271100245447?l=betaamyloid.blogspot.com'/&gt;&lt;/div&gt;&lt;img src="http://feeds.feedburner.com/~r/AmyloidEtal/~4/O4iNieoVCA4" height="1" width="1"/&gt;</description><app:edited xmlns:app="http://www.w3.org/2007/app">2009-10-12T22:59:14.776-07:00</app:edited><thr:total xmlns:thr="http://purl.org/syndication/thread/1.0">0</thr:total><feedburner:origLink>http://betaamyloid.blogspot.com/2009/10/beta-amyloid-1-40-research-paper-beta.html</feedburner:origLink></item><item><title>Beta Amyloid 1 28: Research Paper on Beta Amyloid 1 28</title><link>http://feedproxy.google.com/~r/AmyloidEtal/~3/wF5J3FmhQ3U/beta-amyloid-1-28-research-paper-on.html</link><author>amyloidorg@gmail.com</author><pubDate>Mon, 12 Oct 2009 08:04:57 PDT</pubDate><guid isPermaLink="false">tag:blogger.com,1999:blog-6662563293158062075.post-1987805158957666791</guid><description>&lt;meta equiv="Content-Type" content="text/html; 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&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;div class="blogger-post-footer"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6662563293158062075-163624739759911196?l=betaamyloid.blogspot.com'/&gt;&lt;/div&gt;&lt;img src="http://feeds.feedburner.com/~r/AmyloidEtal/~4/wdP4LTR4xHo" height="1" width="1"/&gt;</description><app:edited xmlns:app="http://www.w3.org/2007/app">2009-10-12T23:00:34.660-07:00</app:edited><thr:total xmlns:thr="http://purl.org/syndication/thread/1.0">0</thr:total><feedburner:origLink>http://betaamyloid.blogspot.com/2009/10/structure-of-beta-amyloid-research.html</feedburner:origLink></item><item><title>Intracellular Amyloid: Research Paper on Intracellular Amyloid</title><link>http://feedproxy.google.com/~r/AmyloidEtal/~3/P6g13P5eloo/intracellular-amyloid-research-paper-on.html</link><author>amyloidorg@gmail.com</author><pubDate>Mon, 12 Oct 2009 23:01:48 PDT</pubDate><guid isPermaLink="false">tag:blogger.com,1999:blog-6662563293158062075.post-7963796564058116694</guid><description>&lt;meta equiv="Content-Type" content="text/html; 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	text-decoration:underline; 	text-underline:single;} h6 	{mso-style-next:Normal; 	margin:0in; 	margin-bottom:.0001pt; 	mso-pagination:widow-orphan; 	page-break-after:avoid; 	mso-outline-level:6; 	font-size:10.0pt; 	mso-bidi-font-size:12.0pt; 	font-family:Arial;} a:link, span.MsoHyperlink 	{color:blue; 	text-decoration:underline; 	text-underline:single;} a:visited, span.MsoHyperlinkFollowed 	{color:purple; 	text-decoration:underline; 	text-underline:single;} @page Section1 	{size:8.5in 11.0in; 	margin:1.0in 1.25in 1.0in 1.25in; 	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;} --&gt; &lt;/style&gt;  &lt;h6&gt;Intracellular Amyloid: Research Paper on Intracellular Amyloid&lt;/h6&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;Kumar A, Dogra S, Prakash A. &lt;b&gt;Protective effect of curcumin (Curcuma longa), against aluminium toxicity: Possible behavioral and biochemical alterations in rats.&lt;/b&gt; &lt;i&gt;Behav Brain Res&lt;/i&gt;. 2009 Dec 28;205(2):384-90. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19616038" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;Nunes AF, Montero M, Franquinho F, Santos SD, Malva J, Zimmer J, Sousa MM. &lt;b&gt;Transthyretin knockout mice display decreased susceptibility to AMPA-induced neurodegeneration.&lt;/b&gt; &lt;i&gt;Neurochem Int&lt;/i&gt;. 2009 Dec;55(7):454-7. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19595729" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt; 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	text-underline:single;} a:link, span.MsoHyperlink 	{color:blue; 	text-decoration:underline; 	text-underline:single;} a:visited, span.MsoHyperlinkFollowed 	{color:purple; 	text-decoration:underline; 	text-underline:single;} @page Section1 	{size:8.5in 11.0in; 	margin:1.0in 1.25in 1.0in 1.25in; 	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;} --&gt; &lt;/style&gt;  &lt;h5&gt;Amyloid Beta Dimers: Research Paper : Amyloid Beta Dimers&lt;/h5&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;Bhak G, Choe YJ, Paik SR. &lt;b&gt;Mechanism of amyloidogenesis: nucleation-dependent fibrillation versus double-concerted fibrillation.&lt;/b&gt; &lt;i&gt;BMB Rep&lt;/i&gt;. 2009 Sep 30;42(9):541-51. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19788854" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;Alboni S, Cervia D, Ross B, Montanari C, Gonzalez AS, Sanchez-Alavez M, Marcondes MC, De Vries D, Sugama S, Brunello N, Blom J, Tascedda F, Conti B. &lt;b&gt;Mapping of the full length and the truncated interleukin-18 receptor alpha in the mouse brain.&lt;/b&gt; &lt;i&gt;J Neuroimmunol&lt;/i&gt;. 2009 Sep 29;214(1-2):43-54. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19640592" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; 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&lt;i&gt;Glycobiology&lt;/i&gt;. 2009 Sep 23; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19776078" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;div class="blogger-post-footer"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6662563293158062075-5469878843254759007?l=betaamyloid.blogspot.com'/&gt;&lt;/div&gt;&lt;img src="http://feeds.feedburner.com/~r/AmyloidEtal/~4/5X0DPDU3iw8" height="1" width="1"/&gt;</description><app:edited xmlns:app="http://www.w3.org/2007/app">2009-10-12T23:02:58.084-07:00</app:edited><thr:total xmlns:thr="http://purl.org/syndication/thread/1.0">0</thr:total><feedburner:origLink>http://betaamyloid.blogspot.com/2009/10/amyloid-beta-dimers-research-paper.html</feedburner:origLink></item><item><title>Tau :Beta Amyloid::Research Paper on Tau  Beta Amyloid</title><link>http://feedproxy.google.com/~r/AmyloidEtal/~3/03oWMVQERmM/tau-beta-amyloid-research-paper-on-tau.html</link><author>amyloidorg@gmail.com</author><pubDate>Mon, 12 Oct 2009 23:04:30 PDT</pubDate><guid isPermaLink="false">tag:blogger.com,1999:blog-6662563293158062075.post-1658192438090244784</guid><description>&lt;meta equiv="Content-Type" content="text/html; 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	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;} --&gt; &lt;/style&gt;  &lt;h4&gt;&lt;strong&gt;&lt;span style=""&gt;Tau :Beta Amyloid:::: Research Paper on Tau &lt;span style=""&gt;&lt;/span&gt;Beta Amyloid&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/h4&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;Bhak G, Choe YJ, Paik SR. &lt;b&gt;Mechanism of amyloidogenesis: nucleation-dependent fibrillation versus double-concerted fibrillation.&lt;/b&gt; &lt;i&gt;BMB Rep&lt;/i&gt;. 2009 Sep 30;42(9):541-51. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19788854" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;Whitwell JL, Jack CR, Boeve BF, Senjem ML, Baker M, Ivnik RJ, Knopman DS, Wszolek ZK, Petersen RC, Rademakers R, Josephs KA. &lt;b&gt;Atrophy patterns in IVS10+16, IVS10+3, N279K, S305N, P301L, and V337M MAPT mutations.&lt;/b&gt; &lt;i&gt;Neurology&lt;/i&gt;. 2009 Sep 29;73(13):1058-65. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19786698" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt; 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&lt;i&gt;Neurosignals&lt;/i&gt;. 2009 Sep 29;18(1):9-23. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19786811" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;Jozefowski S, Marcinkiewicz J. &lt;b&gt;Aggregates of denatured proteins stimulate nitric oxide and superoxide production in macrophages.&lt;/b&gt; &lt;i&gt;Inflamm Res&lt;/i&gt;. 2009 Sep 26; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19784549" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;Smach MA, Charfeddine B, Ben Othman L, Lammouchi T, Dridi H, Nafati S, Ltaief A, Bennamou S, Limem K. &lt;b&gt;Evaluation of Cerebrospinal Fluid Tau/Beta-Amyloid(42) Ratio as Diagnostic Markers for Alzheimer Disease.&lt;/b&gt; &lt;i&gt;Eur Neurol&lt;/i&gt;. 2009 Sep 26;62(6):349-355. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19786779" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;Mlekusch R, Humpel C. &lt;b&gt;Matrix metalloproteinases-2 and -3 are reduced in cerebrospinal fluid with low beta-amyloid(1-42) levels.&lt;/b&gt; &lt;i&gt;Neurosci Lett&lt;/i&gt;. 2009 Sep 26; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19786072" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;Colell A, Fernández A, Fernández-Checa JC. &lt;b&gt;Mitochondria, cholesterol and amyloid beta peptide: a dangerous trio in Alzheimer disease.&lt;/b&gt; &lt;i&gt;J Bioenerg Biomembr&lt;/i&gt;. 2009 Sep 26; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19784764" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; 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&lt;i&gt;J Pharmacol Sci&lt;/i&gt;. 2009 Sep 26; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19783863" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;Xiao L, Zhao D, Chan WH, Choi MM, Li HW. &lt;b&gt;Inhibition of beta 1-40 amyloid fibrillation with N-acetyl-l-cysteine capped quantum dots.&lt;/b&gt; &lt;i&gt;Biomaterials&lt;/i&gt;. 2009 Sep 25; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19783039" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; 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font-family: Arial; font-weight: normal;"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;div class="blogger-post-footer"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6662563293158062075-1658192438090244784?l=betaamyloid.blogspot.com'/&gt;&lt;/div&gt;&lt;img src="http://feeds.feedburner.com/~r/AmyloidEtal/~4/03oWMVQERmM" height="1" width="1"/&gt;</description><app:edited xmlns:app="http://www.w3.org/2007/app">2009-10-12T23:04:30.506-07:00</app:edited><thr:total xmlns:thr="http://purl.org/syndication/thread/1.0">0</thr:total><feedburner:origLink>http://betaamyloid.blogspot.com/2009/10/tau-beta-amyloid-research-paper-on-tau.html</feedburner:origLink></item><item><title>Myeloma: Amyloid Multiple Myeloma: Amyloidosis and Myeloma</title><link>http://feedproxy.google.com/~r/AmyloidEtal/~3/UgGZaNO8b90/myeloma-amyloid-multiple-myeloma.html</link><author>amyloidorg@gmail.com</author><pubDate>Mon, 12 Oct 2009 23:05:49 PDT</pubDate><guid isPermaLink="false">tag:blogger.com,1999:blog-6662563293158062075.post-4912464633752563598</guid><description>&lt;meta equiv="Content-Type" content="text/html; 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&lt;i&gt;Am J Alzheimers Dis Other Demen&lt;/i&gt;. 2009 Sep 23; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19776335" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;Reed-Geaghan EG, Savage JC, Hise AG, Landreth GE. &lt;b&gt;CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation.&lt;/b&gt; &lt;i&gt;J Neurosci&lt;/i&gt;. 2009 Sep 23;29(38):11982-92. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19776284" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt; 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charset=utf-8"&gt;&lt;meta name="ProgId" content="amyloid cascade hypothesis"&gt;&lt;meta name="Generator" content="amyloid cascade hypothesis"&gt;&lt;meta name="Originator" content="amyloid cascade hypothesis"&gt;&lt;link rel="File-List" href="http://betaamyloid.blogspot.com/2009/10/amyloid-cascade-hypothesis-research.html"&gt;&lt;!--[if gte mso 9]&gt;&lt;xml&gt;  &lt;w:worddocument&gt;   &lt;w:view&gt;Normal&lt;/w:View&gt;   &lt;w:zoom&gt;0&lt;/w:Zoom&gt;   &lt;w:donotoptimizeforbrowser/&gt;  &lt;/w:WordDocument&gt; &lt;/xml&gt;&lt;![endif]--&gt;&lt;style&gt; &lt;!--  /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal 	{mso-style-parent:""; 	margin:0in; 	margin-bottom:.0001pt; 	mso-pagination:widow-orphan; 	font-size:12.0pt; 	font-family:"Times New Roman"; 	mso-fareast-font-family:"Times New Roman";} h1 	{mso-style-next:Normal; 	margin:0in; 	margin-bottom:.0001pt; 	mso-pagination:widow-orphan; 	page-break-after:avoid; 	mso-outline-level:1; 	font-size:12.0pt; 	font-family:"Times New Roman"; 	mso-font-kerning:0pt; 	text-decoration:underline; 	text-underline:single;} h2 	{mso-style-next:Normal; 	margin:0in; 	margin-bottom:.0001pt; 	mso-pagination:widow-orphan; 	page-break-after:avoid; 	mso-outline-level:2; 	font-size:10.0pt; 	mso-bidi-font-size:13.5pt; 	font-family:Arial; 	color:blue; 	font-weight:normal;} h3 	{mso-style-next:Normal; 	margin:0in; 	margin-bottom:.0001pt; 	mso-pagination:widow-orphan; 	page-break-after:avoid; 	mso-outline-level:3; 	font-size:10.0pt; 	mso-bidi-font-size:13.5pt; 	font-family:Arial; 	color:blue; 	font-weight:normal;} a:link, span.MsoHyperlink 	{color:blue; 	text-decoration:underline; 	text-underline:single;} a:visited, span.MsoHyperlinkFollowed 	{color:purple; 	text-decoration:underline; 	text-underline:single;} @page Section1 	{size:8.5in 11.0in; 	margin:1.0in 1.25in 1.0in 1.25in; 	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;} --&gt; &lt;/style&gt;  &lt;h3&gt;&lt;strong&gt;The Amyloid Cascade Hypothesis: Research Paper on The Amyloid Cascade Hypothesis&lt;o:p&gt;&lt;/o:p&gt;&lt;/strong&gt;&lt;/h3&gt; 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&lt;i&gt;Neurobiol Dis&lt;/i&gt;. 2009 Oct;36(1):151-61. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19631745" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;span style="font-size: 10pt; font-family: Arial;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/p&gt;  &lt;div class="blogger-post-footer"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6662563293158062075-5111143446340676791?l=betaamyloid.blogspot.com'/&gt;&lt;/div&gt;&lt;img src="http://feeds.feedburner.com/~r/AmyloidEtal/~4/2y8KXQ5wlUs" height="1" width="1"/&gt;</description><app:edited xmlns:app="http://www.w3.org/2007/app">2009-10-12T23:08:24.286-07:00</app:edited><thr:total xmlns:thr="http://purl.org/syndication/thread/1.0">0</thr:total><feedburner:origLink>http://betaamyloid.blogspot.com/2009/10/amyloid-hypothesis-alzheimers-research.html</feedburner:origLink></item><item><title>Amyloid Hypothesis: Research Paper on Amyloid Hypothesis</title><link>http://feedproxy.google.com/~r/AmyloidEtal/~3/X72FhfQendw/amyloid-hypothesis-research-paper-on.html</link><author>amyloidorg@gmail.com</author><pubDate>Mon, 12 Oct 2009 23:09:25 PDT</pubDate><guid isPermaLink="false">tag:blogger.com,1999:blog-6662563293158062075.post-4650181518634307423</guid><description>&lt;meta equiv="Content-Type" content="text/html; 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	text-decoration:underline; 	text-underline:single;} h2 	{mso-style-next:Normal; 	margin:0in; 	margin-bottom:.0001pt; 	mso-pagination:widow-orphan; 	page-break-after:avoid; 	mso-outline-level:2; 	font-size:10.0pt; 	mso-bidi-font-size:13.5pt; 	font-family:Arial; 	color:blue; 	font-weight:normal;} a:link, span.MsoHyperlink 	{color:blue; 	text-decoration:underline; 	text-underline:single;} a:visited, span.MsoHyperlinkFollowed 	{color:purple; 	text-decoration:underline; 	text-underline:single;} @page Section1 	{size:8.5in 11.0in; 	margin:1.0in 1.25in 1.0in 1.25in; 	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;} --&gt; &lt;/style&gt;  &lt;h2&gt;&lt;strong&gt;Amyloid Hypothesis: Research Paper on Amyloid Hypothesis&lt;o:p&gt;&lt;/o:p&gt;&lt;/strong&gt;&lt;/h2&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt; 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charset=utf-8"&gt;&lt;meta name="ProgId" content="amyloid research fund"&gt;&lt;meta name="Generator" content="amyloid research fund"&gt;&lt;meta name="Originator" content="amyloid research fund"&gt;&lt;link rel="File-List" href="http://betaamyloid.blogspot.com/2009/10/amyloid-research-fund-amyloid-research.html"&gt;&lt;link rel="Edit-Time-Data" href="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_editdata.mso"&gt;&lt;!--[if !mso]&gt; &lt;style&gt; v\:* {behavior:url(#default#VML);} o\:* {behavior:url(#default#VML);} w\:* {behavior:url(#default#VML);} .shape {behavior:url(#default#VML);} &lt;/style&gt; &lt;![endif]--&gt;&lt;!--[if gte mso 9]&gt;&lt;xml&gt;  &lt;w:worddocument&gt;   &lt;w:view&gt;Normal&lt;/w:View&gt;   &lt;w:zoom&gt;0&lt;/w:Zoom&gt;   &lt;w:donotoptimizeforbrowser/&gt;  &lt;/w:WordDocument&gt; &lt;/xml&gt;&lt;![endif]--&gt;&lt;style&gt; &lt;!--  /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal 	{mso-style-parent:""; 	margin:0in; 	margin-bottom:.0001pt; 	mso-pagination:widow-orphan; 	font-size:12.0pt; 	font-family:"Times New Roman"; 	mso-fareast-font-family:"Times New Roman";} h1 	{mso-style-next:Normal; 	margin:0in; 	margin-bottom:.0001pt; 	mso-pagination:widow-orphan; 	page-break-after:avoid; 	mso-outline-level:1; 	font-size:12.0pt; 	font-family:"Times New Roman"; 	mso-font-kerning:0pt; 	text-decoration:underline; 	text-underline:single;} a:link, span.MsoHyperlink 	{color:blue; 	text-decoration:underline; 	text-underline:single;} a:visited, span.MsoHyperlinkFollowed 	{color:purple; 	text-decoration:underline; 	text-underline:single;} @page Section1 	{size:8.5in 11.0in; 	margin:1.0in 1.25in 1.0in 1.25in; 	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;} --&gt; &lt;/style&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Amyloid Research Fund: Amyloid Research Grants: Funding on Amyloid Reserach&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://www.alz.org/Research/RGP/ETAC.asp" target="_new"&gt;Everyday Technologies for Alzheimer's Care (ETAC) Research Grants&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;Alzheimer's Association &lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;$200,000 total for up to three years&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;December&lt;!--[if gte vml 1]&gt;&lt;v:shapetype id="_x0000_t75" coordsize="21600,21600" spt="75" preferrelative="t" path="m@4@5l@4@11@9@11@9@5xe" filled="f" stroked="f"&gt;  &lt;v:stroke joinstyle="miter"&gt;  &lt;v:formulas&gt;   &lt;v:f eqn="if lineDrawn pixelLineWidth 0"&gt;   &lt;v:f eqn="sum @0 1 0"&gt;   &lt;v:f eqn="sum 0 0 @1"&gt;   &lt;v:f eqn="prod @2 1 2"&gt;   &lt;v:f eqn="prod @3 21600 pixelWidth"&gt;   &lt;v:f eqn="prod @3 21600 pixelHeight"&gt;   &lt;v:f eqn="sum @0 0 1"&gt;   &lt;v:f eqn="prod @6 1 2"&gt;   &lt;v:f eqn="prod @7 21600 pixelWidth"&gt;   &lt;v:f eqn="sum @8 21600 0"&gt;   &lt;v:f eqn="prod @7 21600 pixelHeight"&gt;   &lt;v:f eqn="sum @10 21600 0"&gt;  &lt;/v:formulas&gt;  &lt;v:path extrusionok="f" gradientshapeok="t" connecttype="rect"&gt;  &lt;o:lock ext="edit" aspectratio="t"&gt; &lt;/v:shapetype&gt;&lt;v:shape id="_x0000_i1025" type="#_x0000_t75" alt="" style="'width:6pt;"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image002.gif" shapes="_x0000_i1025" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1026" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image003.gif" shapes="_x0000_i1026" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1027" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image004.gif" shapes="_x0000_i1027" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1028" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image005.gif" shapes="_x0000_i1028" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1029" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image006.gif" shapes="_x0000_i1029" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://grants.nih.gov/grants/guide/pa-files/PAR-08-183.html" target="_new"&gt;Exploratory Collaborations with National Centers for Biomedical Computing (R21)&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Institutes of Health (NIH) Roadmap Initiatives&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;$275K over 2yrs&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;March 16, July 16, November 16&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1030" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image007.gif" shapes="_x0000_i1030" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1031" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image008.gif" shapes="_x0000_i1031" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1032" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image009.gif" shapes="_x0000_i1032" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1033" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image010.gif" shapes="_x0000_i1033" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1034" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image011.gif" shapes="_x0000_i1034" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://grants.nih.gov/grants/guide/pa-files/PAR-09-219.html" target="_new"&gt;Exploratory Innovations in Biomedical Computational Science and Technology (R21)&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Cancer Institute (NCI)
&lt;br /&gt;National Human Genome Research Institute (NHGRI)
&lt;br /&gt;National Institute on Aging (NIA)
&lt;br /&gt;National Institute of Biomedical Imaging and Bioengineering (NIBIB)
&lt;br /&gt;National Institute on Drug Abuse (NIDA)
&lt;br /&gt;National Institute of Environmental Health Sciences (NIEHS)
&lt;br /&gt;National Institute of General Medical Sciences (NIGMS)
&lt;br /&gt;National Institute of Mental Health (NIMH)
&lt;br /&gt;National Institute of Neurological Disorders and Stroke (NINDS)
&lt;br /&gt;National Institute on Alcohol Abuse and Alcoholism (NIAAA)
&lt;br /&gt;National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
&lt;br /&gt;National Eye Institute (NEI)
&lt;br /&gt;National Institute of Dental and Craniofacial Research&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;$275K over 2 yrs&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;March 16, July 16, November 16&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1035" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image012.gif" shapes="_x0000_i1035" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1036" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image013.gif" shapes="_x0000_i1036" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1037" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image014.gif" shapes="_x0000_i1037" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1038" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image015.gif" shapes="_x0000_i1038" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1039" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image016.gif" shapes="_x0000_i1039" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://grants.nih.gov/grants/guide/pa-files/PAR-08-135.html" target="_new"&gt;Exploratory/Developmental Grant for Complementary and Alternative Medicine (CAM) Studies of Humans (R21)&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Cancer Institute (NCI)
&lt;br /&gt;National Institute on Aging (NIA)
&lt;br /&gt;National Center for Complementary and Alternative Medicine (NCCAM)
&lt;br /&gt;Office of Dietary Supplements (ODS)&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;$400K over 3yrs&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;March 16, July 16, November 16&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1040" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image017.gif" shapes="_x0000_i1040" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1041" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image018.gif" shapes="_x0000_i1041" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1042" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image019.gif" shapes="_x0000_i1042" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1043" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image020.gif" shapes="_x0000_i1043" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1044" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image021.gif" shapes="_x0000_i1044" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://grants.nih.gov/grants/guide/pa-files/PA-08-185.html" target="_new"&gt;Exploratory/Developmental Grant for Complementary and Alternative Medicine (CAM) Studies using Cells, Tissues, and Animal Models of Disease (R21)&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Cancer Institute (NCI)
&lt;br /&gt;National Center for Complementary and Alternative Medicine (NCCAM)
&lt;br /&gt;Office of Dietary Supplements (ODS)&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;$275K over 2yrs&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;March 16, July 16, November 16&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1045" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image022.gif" shapes="_x0000_i1045" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1046" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image023.gif" shapes="_x0000_i1046" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1047" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image024.gif" shapes="_x0000_i1047" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1048" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image025.gif" shapes="_x0000_i1048" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1049" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image026.gif" shapes="_x0000_i1049" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://grants.nih.gov/grants/guide/pa-files/PA-07-459.html" target="_new"&gt;Feasibility Studies to Develop Technology and Methods for Genomics, Population Genomics and ELSI (R21)&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Human Genome Research Institute (NHGRI)
&lt;br /&gt;National Institutes of Health (NIH)
&lt;br /&gt;National Institute of Mental Health (NIMH)
&lt;br /&gt;National Institute of Dental and Craniofacial Research&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;$300K over 2yrs&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;16 February, 16 June, 16 October&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1050" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image027.gif" shapes="_x0000_i1050" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1051" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image028.gif" shapes="_x0000_i1051" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1052" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image029.gif" shapes="_x0000_i1052" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1053" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image030.gif" shapes="_x0000_i1053" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1054" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image031.gif" shapes="_x0000_i1054" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://grants.nih.gov/grants/guide/pa-files/PA-07-033.html" target="_new"&gt;Focal Cognitive Deficits in CNS Disorders (R01)&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Institute on Aging (NIA)
&lt;br /&gt;National Institute of Child Health and Human Development (NICHD)
&lt;br /&gt;National Institutes of Health (NIH)
&lt;br /&gt;National Institute of Neurological Disorders and Stroke (NINDS)
&lt;br /&gt;Office of Behavioral and Social Science Research
&lt;br /&gt;National Institute of Nursing Research&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;See program for details&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;February 5 June 5 October 5&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1055" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image032.gif" shapes="_x0000_i1055" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1056" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image033.gif" shapes="_x0000_i1056" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1057" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image034.gif" shapes="_x0000_i1057" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1058" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image035.gif" shapes="_x0000_i1058" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1059" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image036.gif" shapes="_x0000_i1059" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://grants.nih.gov/grants/guide/pa-files/PA-07-034.html" target="_new"&gt;Focal Cognitive Deficits in CNS Disorders (R03)&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Institute on Aging (NIA)
&lt;br /&gt;National Institutes of Health (NIH)
&lt;br /&gt;Office of Behavioral and Social Science Research
&lt;br /&gt;National Institute of Nursing Research&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;$50K/yr for 2 yrs&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;February 1, June 1, October 1 &lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1060" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image037.gif" shapes="_x0000_i1060" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1061" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image038.gif" shapes="_x0000_i1061" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1062" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image039.gif" shapes="_x0000_i1062" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1063" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image040.gif" shapes="_x0000_i1063" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1064" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image041.gif" shapes="_x0000_i1064" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://grants.nih.gov/grants/guide/pa-files/PA-07-035.html" target="_new"&gt;Focal Cognitive Deficits in CNS Disorders (R21)&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Institute on Aging (NIA)
&lt;br /&gt;National Institutes of Health (NIH)
&lt;br /&gt;National Institute of Neurological Disorders and Stroke (NINDS)
&lt;br /&gt;Office of Behavioral and Social Science Research
&lt;br /&gt;National Institute of Nursing Research&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;$50,000/yr for 2 yrs&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;February 1, June 1, October 1 &lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1065" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image042.gif" shapes="_x0000_i1065" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1066" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image043.gif" shapes="_x0000_i1066" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1067" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image044.gif" shapes="_x0000_i1067" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1068" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image045.gif" shapes="_x0000_i1068" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://www.fic.nih.gov/programs/firca.html" target="_new"&gt;Fogarty International Research Collaboration Award (FIRCA)&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Institutes of Health (NIH)&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;$32,000 per year direct costs&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;January 21, May 21, September 21.&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1069" type="#_x0000_t75" alt="" style="'width:.75pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image046.gif" shapes="_x0000_i1069" width="1" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1070" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image047.gif" shapes="_x0000_i1070" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1071" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image048.gif" shapes="_x0000_i1071" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1072" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image049.gif" shapes="_x0000_i1072" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1073" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image050.gif" shapes="_x0000_i1073" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://www.jdfaf.org/research_funding.htm" target="_new"&gt;French Foundation Fellowship&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;The John Douglas French Alzheimer's Foundation&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;2 years, at a salary of $35,000 per year&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;Annually in November&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1074" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image051.gif" shapes="_x0000_i1074" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1075" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image052.gif" shapes="_x0000_i1075" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1076" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image053.gif" shapes="_x0000_i1076" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1077" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image054.gif" shapes="_x0000_i1077" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://grants.nih.gov/grants/guide/pa-files/PA-08-097.html" target="_new"&gt;Functional Links between the Immune System, Brain Function and Behavior (R01)&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Cancer Institute (NCI)
&lt;br /&gt;National Institute on Aging (NIA)
&lt;br /&gt;National Institute of Biomedical Imaging and Bioengineering (NIBIB)
&lt;br /&gt;National Institute on Drug Abuse (NIDA)
&lt;br /&gt;National Institute of Mental Health (NIMH)
&lt;br /&gt;National Institute of Neurological Disorders and Stroke (NINDS)
&lt;br /&gt;National Center for Complementary and Alternative Medicine (NCCAM)
&lt;br /&gt;National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;See program for details.&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;March 5, July 5, November 5&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1078" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image055.gif" shapes="_x0000_i1078" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1079" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image056.gif" shapes="_x0000_i1079" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1080" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image057.gif" shapes="_x0000_i1080" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1081" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image058.gif" shapes="_x0000_i1081" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1082" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image059.gif" shapes="_x0000_i1082" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://grants.nih.gov/grants/guide/pa-files/PA-08-098.html" target="_new"&gt;Functional Links between the Immune System, Brain Function and Behavior (R21)&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Cancer Institute (NCI)
&lt;br /&gt;National Institute on Aging (NIA)
&lt;br /&gt;National Institute of Biomedical Imaging and Bioengineering (NIBIB)
&lt;br /&gt;National Institute on Drug Abuse (NIDA)
&lt;br /&gt;National Institute of Mental Health (NIMH)
&lt;br /&gt;National Institute of Neurological Disorders and Stroke (NINDS)
&lt;br /&gt;National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;$275K over 2yrs.&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt; March 16, July 16, November 16&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1083" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image060.gif" shapes="_x0000_i1083" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1084" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image061.gif" shapes="_x0000_i1084" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1085" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image062.gif" shapes="_x0000_i1085" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1086" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image063.gif" shapes="_x0000_i1086" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1087" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image064.gif" shapes="_x0000_i1087" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://grants.nih.gov/grants/guide/pa-files/PA-08-255.html" target="_new"&gt;Functioning of People with Mental Disorders (R01)&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Institute of Mental Health (NIMH)&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;See program for details&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;March 5, July 5, November 5&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1088" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image065.gif" shapes="_x0000_i1088" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1089" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image066.gif" shapes="_x0000_i1089" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1090" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image067.gif" shapes="_x0000_i1090" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1091" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image068.gif" shapes="_x0000_i1091" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1092" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image069.gif" shapes="_x0000_i1092" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://www.gairdner.org/nominations2007gairdner.html" target="_new"&gt;Gairdner International Awards&lt;/a&gt;&lt;b&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/b&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;Gairdner Foundation&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;$30,000 CAD&lt;b&gt;Deadline(s):  &lt;/b&gt;15 October annually&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1093" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image070.gif" shapes="_x0000_i1093" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1094" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image071.gif" shapes="_x0000_i1094" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1095" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image072.gif" shapes="_x0000_i1095" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1096" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image073.gif" shapes="_x0000_i1096" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1097" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image074.gif" shapes="_x0000_i1097" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://grants.nih.gov/grants/guide/pa-files/PA-07-457.html" target="_new"&gt;Genetic and Genomic Resources for Emerging Non-Mammalian Model Organisms (R24)&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Institute of General Medical Sciences (NIGMS)
&lt;br /&gt;National Institutes of Health (NIH)&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;$250K/yr for up to 4yrs. See program for details.&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;25 January, 25 May, 25 September&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1098" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image075.gif" shapes="_x0000_i1098" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1099" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image076.gif" shapes="_x0000_i1099" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1100" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image077.gif" shapes="_x0000_i1100" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1101" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image078.gif" shapes="_x0000_i1101" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://grants.nih.gov/grants/guide/pa-files/PAR-08-138.html" target="_new"&gt;Genetic Screens to Enhance Zebrafish Research (R01)&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Cancer Institute (NCI)
&lt;br /&gt;National Heart, Lung, and Blood Institute (NHLBI)
&lt;br /&gt;National Institute on Aging (NIA)
&lt;br /&gt;National Institute of Child Health and Human Development (NICHD)
&lt;br /&gt;National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
&lt;br /&gt;National Institute on Drug Abuse (NIDA)
&lt;br /&gt;National Institute of Environmental Health Sciences (NIEHS)
&lt;br /&gt;National Institute of Neurological Disorders and Stroke (NINDS)
&lt;br /&gt;National Institute on Alcohol Abuse and Alcoholism (NIAAA)
&lt;br /&gt;National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
&lt;br /&gt;National Institute of Dental and Craniofacial Research
&lt;br /&gt;National Institute on Deafness and Other Communication Disorders&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;Up to $500K/yr for 5 yrs. See program for details.&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;Letters of Intent Receipt Date(s): August 25, 2008, August 25, 2009, August 25, 2010; Application Due Date(s): September 24, 2008, September 24, 2009, September 24, 2010&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1102" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image079.gif" shapes="_x0000_i1102" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1103" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image080.gif" shapes="_x0000_i1103" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1104" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image081.gif" shapes="_x0000_i1104" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1105" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image082.gif" shapes="_x0000_i1105" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1106" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image083.gif" shapes="_x0000_i1106" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-06-033.html" target="_new"&gt;Genome-wide Association Studies in the Genes and Environment Initiative - Study Investigators (U01)&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Human Genome Research Institute (NHGRI)
&lt;br /&gt;National Institutes of Health (NIH)&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;$10 million (total costs) over 2 yrs&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;Application Receipt Date(s): November 29, 2006&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1107" type="#_x0000_t75" alt="" style="'width:.75pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image046.gif" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image046.gif" shapes="_x0000_i1107" width="1" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1108" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image084.gif" shapes="_x0000_i1108" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1109" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image085.gif" shapes="_x0000_i1109" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1110" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image086.gif" shapes="_x0000_i1110" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1111" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image087.gif" shapes="_x0000_i1111" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://www.hhmi.org/grants/individuals/medfellows.html" target="_new"&gt;Graduate Program - Research Training Fellowships for Medical Students&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;Howard Hughes Medical Institute&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;$25,000 per year and other allowances&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;Annually in January&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1112" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image088.gif" shapes="_x0000_i1112" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1113" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image089.gif" shapes="_x0000_i1113" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1114" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image090.gif" shapes="_x0000_i1114" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1115" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image091.gif" shapes="_x0000_i1115" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1116" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image092.gif" shapes="_x0000_i1116" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-10-008.html" target="_new"&gt;Healthy Aging through Behavioral Economic Analyses of Situations (R01)&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Institute on Aging (NIA)&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;$175K/yr for up to 3yrs.&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;Letters of Intent Receipt Date(s): October 2, 2009; Application Due Date: November 2, 2009&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1117" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image093.gif" shapes="_x0000_i1117" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1118" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image094.gif" shapes="_x0000_i1118" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1119" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image095.gif" shapes="_x0000_i1119" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1120" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image096.gif" shapes="_x0000_i1120" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1121" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image097.gif" shapes="_x0000_i1121" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://www.hhmi.org/cloister/" target="_new"&gt;HHMI-NIH Research Scholars&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;Howard Hughes Medical Institute&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;See program for details.&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Deadline(s):  &lt;/b&gt;Annually in January&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1122" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image098.gif" shapes="_x0000_i1122" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1123" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image099.gif" shapes="_x0000_i1123" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1124" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image100.gif" shapes="_x0000_i1124" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1125" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image101.gif" shapes="_x0000_i1125" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1126" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image102.gif" shapes="_x0000_i1126" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Program:  &lt;/b&gt;&lt;a href="http://grants.nih.gov/grants/guide/pa-files/PA-08-001.html" target="_new"&gt;High Throughput Tools for Brain and Behavior (SBIR [R43/R44])&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Sponsor(s):  &lt;/b&gt;National Institutes of Health (NIH)
&lt;br /&gt;National Institute of Mental Health (NIMH)
&lt;br /&gt;National Institute of Neurological Disorders and Stroke (NINDS)
&lt;br /&gt;Canadian Institutes of Health Research&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;Award:  &lt;/b&gt;Up to $300K/yr for 2 yrs for Phase I. Up to $500K/yr for 3 yrs for Phase II.&lt;b&gt;Deadline(s):  &lt;/b&gt;5 April, 5 August, 5 December&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1127" type="#_x0000_t75" alt="" style="'width:6pt;height:11.25pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image103.gif" shapes="_x0000_i1127" width="8" border="0" height="15" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1128" type="#_x0000_t75" alt="" style="'width:6pt;height:1.5pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image104.gif" shapes="_x0000_i1128" width="8" border="0" height="2" /&gt;&lt;!--[endif]--&gt;&lt;!--[if gte vml 1]&gt;&lt;v:shape id="_x0000_i1129" type="#_x0000_t75" alt="" style="'width:6pt;height:.75pt'"&gt;  &lt;v:imagedata src="file:///C:/DOCUME~1/sanjay/LOCALS~1/Temp/msoclip1/01/clip_image001.png" href="http://www.alzforum.org/images/spacer.gif"&gt; &lt;/v:shape&gt;&lt;![endif]--&gt;&lt;!--[if !vml]--&gt;&lt;img src="file:///C:/DOCUME%7E1/sanjay/LOCALS%7E1/Temp/msoclip1/01/clip_image105.gif" shapes="_x0000_i1129" width="8" border="0" height="1" /&gt;&lt;!--[endif]--&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;High Throughput Tools for Brain and Behavior (STTR [R41/R42])&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Institutes of Health (NIH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Mental Health (NIMH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Neurological Disorders and Stroke (NINDS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;Up to $300K/yr for 2 yrs for Phase I. Up to $500K/yr for 3 yrs for Phase II.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;5 April, 5 August, 5 December&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;HIV Infection Of The Central Nervous System (R01)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Institute on Drug Abuse (NIDA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institutes of Health (NIH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Mental Health (NIMH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Neurological Disorders and Stroke (NINDS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Alcohol Abuse and Alcoholism (NIAAA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;May 1, September 1, January 2&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Human Pluripotent Stem Cell (hPSC) Research Using Non-Embryonic Sources (R01)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Center for Research Resources (NCRR)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Heart, Lung, and Blood Institute (NHLBI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Aging (NIA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Allergy And Infectious Diseases (NIAID)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Child Health and Human Development (NICHD)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of General Medical Sciences (NIGMS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institutes of Health (NIH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Mental Health (NIMH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Neurological Disorders and Stroke (NINDS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Alcohol Abuse and Alcoholism (NIAAA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Eye Institute (NEI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Dental and Craniofacial Research&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;5 February, 5 June, 5 October&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Human Pluripotent Stem Cell (hPSC) Research Using Non-Embryonic Sources (R21)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Center for Research Resources (NCRR)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Heart, Lung, and Blood Institute (NHLBI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Aging (NIA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Allergy And Infectious Diseases (NIAID)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Child Health and Human Development (NICHD)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of General Medical Sciences (NIGMS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institutes of Health (NIH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Mental Health (NIMH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Neurological Disorders and Stroke (NINDS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Alcohol Abuse and Alcoholism (NIAAA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Eye Institute (NEI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Dental and Craniofacial Research&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;$275K over 2 yrs. See program for details.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;16 February, 16 June, 16 October&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Implicating Noncoding RNAs in the Genetics of Mental Disorders (Collaborative R01)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Institutes of Health (NIH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Mental Health (NIMH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;5 Feb, 5 June, 5 October&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Implicating Noncoding RNAs in the Genetics of Mental Disorders (R01)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Institutes of Health (NIH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Mental Health (NIMH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;5 February, 5 June, 5 October&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Implicating Noncoding RNAs in the Genetics of Mental Disorders (R21)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Institutes of Health (NIH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Mental Health (NIMH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;16 February, 16 June, 16 October&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Improving Diet and Physical Activity Assessment (R01)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Cancer Institute (NCI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Heart, Lung, and Blood Institute (NHLBI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Aging (NIA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Child Health and Human Development (NICHD)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Office of Dietary Supplements (ODS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Nursing Research&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;Letters of Intent Receipt Dates: (new applications) September 5, 2009; May 5, 2010; January 5, 2011; September 5, 2011; May 5, 2012 Letters of Intent Receipt Dates: (resubmission and revision applications) October 5, 2009; June 5, 2010; February 5, 2011; October 5, 2011; June 5, 2012&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Improving Diet and Physical Activity Assessment (R21)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Cancer Institute (NCI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Heart, Lung, and Blood Institute (NHLBI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Aging (NIA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Child Health and Human Development (NICHD)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Nursing Research&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;$275K over 2yrs&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;Letters of Intent Receipt Dates: (new applications) September 16, 2009; May 16, 2010; January 16, 2011; September 16, 2011; May 16, 2012. Letters of Intent Receipt Dates: (renewal, resubmission, and revision applications) October 16, 2009; June 16, 2010; February 16, 2011; October 16, 2011; June 16, 2012.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Independent Scientist Award (K02)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Institute on Aging (NIA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Allergy And Infectious Diseases (NIAID)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Child Health and Human Development (NICHD)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Drug Abuse (NIDA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Environmental Health Sciences (NIEHS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institutes of Health (NIH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Mental Health (NIMH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Neurological Disorders and Stroke (NINDS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Alcohol Abuse and Alcoholism (NIAAA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Office of Dietary Supplements (ODS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Dental and Craniofacial Research&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;March 12, July 12, November 12&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Information Technologies and the Internet in Health Services and Intervention Delivery (R01)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Cancer Institute (NCI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institutes of Health (NIH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Mental Health (NIMH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;March 5, July 5, November 5&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Institutional Clinical and Translational Science Award (U54)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Institutes of Health (NIH) Roadmap Initiatives&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;Letters of Intent Receipt Date: May 3, 2010; Application Receipt Date: June 1, 2010&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;International Research Collaboration – Basic Biomedical (FIRCA-BB)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Institute on Aging (NIA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Biomedical Imaging and Bioengineering (NIBIB)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Environmental Health Sciences (NIEHS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institutes of Health (NIH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;Direct cost of $32,000 per year for up to three years.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;January 21, May 21, September 21&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Investigator-Initiated Research Grants&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;Alzheimer's Association&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;60 awards-Each limited to $240,000 (direct and indirect) for up to three years&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;December&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;ISOA Academic Drug Development Program&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;Institute for the Study of Aging&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;Contact ISOA&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;ISOA Academic Drug Discovery Program&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;Institute for the Study of Aging&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;Contact ISOA&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;ISOA Biotechnology Development Program&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;Institute for the Study of Aging&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;Contact ISOA&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;ISOA Biotechnology Founder's Program&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;Institute for the Study of Aging&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;Contact ISOA&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Jointly Sponsored Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences (T32)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Institute on Aging (NIA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Child Health and Human Development (NICHD)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Drug Abuse (NIDA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of General Medical Sciences (NIGMS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Mental Health (NIMH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Neurological Disorders and Stroke (NINDS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Alcohol Abuse and Alcoholism (NIAAA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Eye Institute (NEI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Deafness and Other Communication Disorders&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;Letters of Intent Submission Date(s): April 25; Application Submission Date(s): May 25&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Lab to Marketplace: Tools for Brain and Behavioral Research (SBIR [R43/R44])&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Institute on Aging (NIA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Drug Abuse (NIDA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institutes of Health (NIH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Mental Health (NIMH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Center for Complementary and Alternative Medicine (NCCAM)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Alcohol Abuse and Alcoholism (NIAAA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Nursing Research&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;Up to $350K/yr for 2yrs for Phase I. Up to $600K/yr for 3yrs for Phase II.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;16 February, 16 June, 16 October&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Limited Competition: Renewal of Aging Intervention Testing Program (U01)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Institute on Aging (NIA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;$500K/yr for up to 5yrs&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;Letters of Intent Receipt Date: December 16, 2008;Application Receipt Date(s): January 16, 2009&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;McKnight Scholars Award&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;The McKnight Endowment Fund for Neuroscience&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;Each scholarship at $75,000 annually for 3 years&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;Annually in January&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;McKnight Technological Innovations in Neuroscience&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;The McKnight Endowment Fund for Neuroscience&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;$100,000 annually for two years&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;Annually in December&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Mechanisms of Functional Recovery After Stroke (R01)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Institute on Aging (NIA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Child Health and Human Development (NICHD)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Neurological Disorders and Stroke (NINDS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Deafness and Other Communication Disorders&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;February 5, June 5, October 5&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Mechanisms of Functional Recovery After Stroke (R21)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Institute on Aging (NIA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Child Health and Human Development (NICHD)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Neurological Disorders and Stroke (NINDS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Deafness and Other Communication Disorders&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;February 16, June 16, October 16&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Mechanisms Underlying the Links between Psychosocial Stress, Aging, the Brain and the Body (R01)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Cancer Institute (NCI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Aging (NIA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Mental Health (NIMH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;February 5, June 5, October 5&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Mentored Clinical Scientist Research Career Development Award (K08)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Cancer Institute (NCI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Heart, Lung, and Blood Institute (NHLBI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Aging (NIA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institutes of Health (NIH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Center for Complementary and Alternative Medicine (NCCAM)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Eye Institute (NEI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;February 1, June 1, October 1&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Program:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;         &lt;/span&gt;Mentored Clinical Scientist Research Career Development Award (K08)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Sponsor(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;National Cancer Institute (NCI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Heart, Lung, and Blood Institute (NHLBI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Aging (NIA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Allergy And Infectious Diseases (NIAID)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Biomedical Imaging and Bioengineering (NIBIB)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Child Health and Human Development (NICHD)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Drug Abuse (NIDA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Environmental Health Sciences (NIEHS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of General Medical Sciences (NIGMS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Mental Health (NIMH)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Neurological Disorders and Stroke (NINDS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Center for Complementary and Alternative Medicine (NCCAM)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Alcohol Abuse and Alcoholism (NIAAA)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Office of Dietary Supplements (ODS)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Eye Institute (NEI)&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute of Dental and Craniofacial Research&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;National Institute on Deafness and Other Communication Disorders&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Award:&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;            &lt;/span&gt;See program for details.&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;Deadline(s):&lt;span style=""&gt;  &lt;/span&gt;&lt;span style=""&gt;     &lt;/span&gt;March 12, July 12, November 12&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;span style=""&gt;            &lt;/span&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;div class="blogger-post-footer"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6662563293158062075-1252220220003341548?l=betaamyloid.blogspot.com'/&gt;&lt;/div&gt;&lt;img src="http://feeds.feedburner.com/~r/AmyloidEtal/~4/dc8fZRsfHIw" height="1" width="1"/&gt;</description><app:edited xmlns:app="http://www.w3.org/2007/app">2009-10-12T23:10:39.421-07:00</app:edited><thr:total xmlns:thr="http://purl.org/syndication/thread/1.0">0</thr:total><feedburner:origLink>http://betaamyloid.blogspot.com/2009/10/amyloid-research-fund-amyloid-research.html</feedburner:origLink></item><item><title>Beta Amyloid Fibrils: Research Papers on Beta Amyloid Fibrils</title><link>http://feedproxy.google.com/~r/AmyloidEtal/~3/ilhP4nazVMU/beta-amyloid-fibrils-research-papers-on.html</link><author>amyloidorg@gmail.com</author><pubDate>Mon, 12 Oct 2009 23:11:30 PDT</pubDate><guid isPermaLink="false">tag:blogger.com,1999:blog-6662563293158062075.post-472369397141196745</guid><description>&lt;meta equiv="Content-Type" content="text/html; charset=utf-8"&gt;&lt;meta name="ProgId" content="beta amyloid fibrils"&gt;&lt;meta name="Generator" content="beta amyloid fibrils"&gt;&lt;meta name="Originator" content="beta amyloid fibrils"&gt;&lt;link rel="File-List" href="http://betaamyloid.blogspot.com/2009/10/beta-amyloid-fibrils-research-papers-on.html"&gt;&lt;!--[if gte mso 9]&gt;&lt;xml&gt;  &lt;w:worddocument&gt;   &lt;w:view&gt;Normal&lt;/w:View&gt;   &lt;w:zoom&gt;0&lt;/w:Zoom&gt;   &lt;w:donotoptimizeforbrowser/&gt;  &lt;/w:WordDocument&gt; &lt;/xml&gt;&lt;![endif]--&gt;&lt;style&gt; &lt;!--  /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal 	{mso-style-parent:""; 	margin:0in; 	margin-bottom:.0001pt; 	mso-pagination:widow-orphan; 	font-size:12.0pt; 	font-family:"Times New Roman"; 	mso-fareast-font-family:"Times New Roman";} h1 	{mso-style-next:Normal; 	margin:0in; 	margin-bottom:.0001pt; 	mso-pagination:widow-orphan; 	page-break-after:avoid; 	mso-outline-level:1; 	font-size:12.0pt; 	font-family:"Times New Roman"; 	mso-font-kerning:0pt; 	text-decoration:underline; 	text-underline:single;} a:link, span.MsoHyperlink 	{color:blue; 	text-decoration:underline; 	text-underline:single;} a:visited, span.MsoHyperlinkFollowed 	{color:purple; 	text-decoration:underline; 	text-underline:single;} @page Section1 	{size:8.5in 11.0in; 	margin:1.0in 1.25in 1.0in 1.25in; 	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;} --&gt; &lt;/style&gt;  &lt;p class="MsoNormal"&gt;&lt;b&gt;&lt;u&gt;Beta Amyloid Fibrils: Research Papers on Beta Amyloid Fibrils&lt;o:p&gt;&lt;/o:p&gt;&lt;/u&gt;&lt;/b&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Quiroz-Baez R, Rojas E, Arias C. &lt;b&gt;Oxidative stress promotes JNK-dependent amyloidogenic processing of normally expressed human APP by differential modification of alpha-, beta- and gamma-secretase expression.&lt;/b&gt; &lt;i&gt;Neurochem Int&lt;/i&gt;. 2009 Dec;55(7):662-70. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19560504" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Nunes AF, Montero M, Franquinho F, Santos SD, Malva J, Zimmer J, Sousa MM. &lt;b&gt;Transthyretin knockout mice display decreased susceptibility to AMPA-induced neurodegeneration.&lt;/b&gt; &lt;i&gt;Neurochem Int&lt;/i&gt;. 2009 Dec;55(7):454-7. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19595729" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Milton NG, Harris JR. &lt;b&gt;Polymorphism of amyloid-beta fibrils and its effects on human erythrocyte catalase binding.&lt;/b&gt; &lt;i&gt;Micron&lt;/i&gt;. 2009 Dec;40(8):800-10. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19683452" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Arrázola MS, Varela-Nallar L, Colombres M, Toledo EM, Cruzat F, Pavez L, Assar R, Aravena A, González M, Montecino M, Maass A, Martínez S, Inestrosa NC. &lt;b&gt;Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.&lt;/b&gt; &lt;i&gt;J Cell Physiol&lt;/i&gt;. 2009 Dec;221(3):658-67. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19711354" target="_blank"&gt;PubMed Abstract&lt;/a&gt; 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	mso-font-kerning:0pt; 	text-decoration:underline; 	text-underline:single;} a:link, span.MsoHyperlink 	{color:blue; 	text-decoration:underline; 	text-underline:single;} a:visited, span.MsoHyperlinkFollowed 	{color:purple; 	text-decoration:underline; 	text-underline:single;} @page Section1 	{size:8.5in 11.0in; 	margin:1.0in 1.25in 1.0in 1.25in; 	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;} --&gt; &lt;/style&gt;  &lt;h1&gt;Vaccine Against Amyloid Beta: Research Paper on Vaccine Against Amyloid Beta&lt;/h1&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Peng Y, Xing C, Xu S, Lemere CA, Chen G, Liu B, Wang L, Feng Y, Wang X. &lt;b&gt;l-3-n-butylphthalide improves cognitive impairment induced by intracerebroventricular infusion of amyloid-beta peptide in rats.&lt;/b&gt; &lt;i&gt;Eur J Pharmacol&lt;/i&gt;. 2009 Oct 25;621(1-3):38-45. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19737553" target="_blank"&gt;PubMed Abstract&lt;/a&gt; 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&lt;i&gt;J Biol Chem&lt;/i&gt;. 2009 Oct 2;284(40):27252-64. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19651786" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;div class="blogger-post-footer"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6662563293158062075-5266537094556354495?l=betaamyloid.blogspot.com'/&gt;&lt;/div&gt;&lt;img src="http://feeds.feedburner.com/~r/AmyloidEtal/~4/KHLlNo1DW38" height="1" width="1"/&gt;</description><app:edited xmlns:app="http://www.w3.org/2007/app">2009-10-12T23:12:52.708-07:00</app:edited><thr:total xmlns:thr="http://purl.org/syndication/thread/1.0">0</thr:total><feedburner:origLink>http://betaamyloid.blogspot.com/2009/10/vaccine-against-amyloid-beta-research.html</feedburner:origLink></item><item><title>Beta Amyloid Vaccine: Research Paper on Beta Amyloid Vaccine.</title><link>http://feedproxy.google.com/~r/AmyloidEtal/~3/m5ByhjWVLwU/beta-amyloid-vaccine.html</link><author>amyloidorg@gmail.com</author><pubDate>Mon, 12 Oct 2009 23:14:06 PDT</pubDate><guid isPermaLink="false">tag:blogger.com,1999:blog-6662563293158062075.post-5837374792675671311</guid><description>&lt;meta equiv="Content-Type" content="text/html; 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&lt;i&gt;Colloids Surf B Biointerfaces&lt;/i&gt;. 2009 Nov 1;74(1):59-66. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19619991" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Edison P, Brooks DJ, Turkheimer FE, Archer HA, Hinz R. &lt;b&gt;Strategies for the generation of parametric images of [11C]PIB with plasma input functions considering discriminations and reproducibility.&lt;/b&gt; &lt;i&gt;Neuroimage&lt;/i&gt;. 2009 Nov 1;48(2):329-38. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19591948" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt; 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&lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Carro EM. &lt;b&gt;Therapeutic Approaches of Leptin in Alzheimer's Disease.&lt;/b&gt; &lt;i&gt;Recent Pat CNS Drug Discov&lt;/i&gt;. 2009 Nov 1; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19515011" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Zhang JJ, Zhang RF, Meng XK. &lt;b&gt;Protective effect of pyrroloquinoline quinone against Abeta-induced neurotoxicity in human neuroblastoma SH-SY5Y cells.&lt;/b&gt; &lt;i&gt;Neurosci Lett&lt;/i&gt;. 2009 Oct 30;464(3):165-9. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19699263" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Mouton PR, Chachich ME, Quigley C, Spangler E, Ingram DK. &lt;b&gt;Caloric restriction attenuates amyloid deposition in middle-aged dtg APP/PS1 mice.&lt;/b&gt; &lt;i&gt;Neurosci Lett&lt;/i&gt;. 2009 Oct 30;464(3):184-7. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19699265" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Giuliani F, Vernay A, Leuba G, Schenk F. &lt;b&gt;Decreased behavioral impairments in an Alzheimer mice model by interfering with TNF-alpha metabolism.&lt;/b&gt; &lt;i&gt;Brain Res Bull&lt;/i&gt;. 2009 Oct 28;80(4-5):302-8. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19622386" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Beeler N, Riederer BM, Waeber G, Abderrahmani A. &lt;b&gt;Role of the JNK-interacting protein 1/islet brain 1 in cell degeneration in Alzheimer disease and diabetes.&lt;/b&gt; &lt;i&gt;Brain Res Bull&lt;/i&gt;. 2009 Oct 28;80(4-5):274-81. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19616077" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Morita M, Osoda K, Yamazaki M, Shirai F, Matsuoka N, Arakawa H, Nishimura S. &lt;b&gt;Effects of non-steroidal anti-inflammatory drugs on Abeta deposition in Abeta(1-42) transgenic C. elegans.&lt;/b&gt; &lt;i&gt;Brain Res&lt;/i&gt;. 2009 Oct 27;1295:186-91. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19666013" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-weight: normal;font-family:Arial;font-size:10;"  &gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;div class="blogger-post-footer"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6662563293158062075-5837374792675671311?l=betaamyloid.blogspot.com'/&gt;&lt;/div&gt;&lt;img src="http://feeds.feedburner.com/~r/AmyloidEtal/~4/m5ByhjWVLwU" height="1" width="1"/&gt;</description><app:edited xmlns:app="http://www.w3.org/2007/app">2009-10-12T23:14:06.439-07:00</app:edited><thr:total xmlns:thr="http://purl.org/syndication/thread/1.0">0</thr:total><feedburner:origLink>http://betaamyloid.blogspot.com/2009/10/beta-amyloid-vaccine.html</feedburner:origLink></item><item><title>Beta Amyloid Deposition: Amyloid Deposition: Reserach Papers on Amyloid Peptides Deposition</title><link>http://feedproxy.google.com/~r/AmyloidEtal/~3/5uicTtjOI7k/beta-amyloid-deposition-amyloid.html</link><author>amyloidorg@gmail.com</author><pubDate>Mon, 12 Oct 2009 23:15:08 PDT</pubDate><guid isPermaLink="false">tag:blogger.com,1999:blog-6662563293158062075.post-5717185379159536075</guid><description>&lt;meta equiv="Content-Type" content="text/html; 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&lt;br /&gt;&lt;/p&gt;&lt;p class="MsoNormal"&gt;Nunes AF, Montero M, Franquinho F, Santos SD, Malva J, Zimmer J, Sousa MM. &lt;b&gt;Transthyretin knockout mice display decreased susceptibility to AMPA-induced neurodegeneration.&lt;/b&gt; &lt;i&gt;Neurochem Int&lt;/i&gt;. 2009 Dec;55(7):454-7. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19595729" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Transthyretin (TTR) has been regarded as a neuroprotective protein given that TTR knockout (KO) mice display increased susceptibility for amyloid beta deposition and memory deficits during aging. In parallel, TTR KO mice have increased levels of neuropeptide Y (NPY), which promotes neuroprotection and neuroproliferation. In this work, we aimed at evaluating TTR neuroprotective effect against an excitotoxic insult that is known to be prevented by NPY action. We show that despite a putative neuroprotective role of TTR, hippocampal slice cultures from TTR KO mice display a decreased susceptibility to AMPA-induced neurodegeneration. We also suggest that increased NPY levels in TTR KO mice are not associated with increased cell proliferation in the dentate gyrus or subventricular zone. In summary, the alleged neuroprotective role of TTR in the nervous system should be regarded with caution and should not be generalized to all types of insults.&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Lin MS, Chen XB, Wang SS, Chang Y, Chen WY. &lt;b&gt;Dynamic fluorescence imaging analysis to investigate the cholesterol recruitment in lipid monolayer during the interaction between beta-amyloid (1-40) and lipid monolayers.&lt;/b&gt; &lt;i&gt;Colloids Surf B Biointerfaces&lt;/i&gt;. 2009 Nov 1;74(1):59-66. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19619991" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Extracellular beta-amyloid (Abeta) deposit is considered as one of the primary factors in inducing Alzheimer's disease (AD). However, the mechanism of Abeta deposition on the cell membrane and the induced cytotoxicity are still unclear. On the basis of the previous reports and results, we propose the "Recruiting Hypothesis" on the interaction between the plasma membrane and Abeta. Recently, many studies focused on cholesterol, which is considered as an important factor for AD. The most challenging issue in studying the cholesterol is non-ideal mixing behavior and non-dynamic analysis. In the present study, we investigated the cholesterol recruitment in the lipid monolayer during the interaction between beta-amyloid peptides Abeta (1-40) and lipid monolayers by dynamic fluorescent imaging analysis. Results from lipid monolayer trough studies showed that the rate of Abeta adsorption onto lipid monolayer is mainly due to the electrostatic effect which is sensitive to the lipid monolayer composition. From the fluorescence imaging analysis, the interaction of Abeta with lipid monolayer containing negative charge lipid and cholesterol brings out the recruiting behavior of the cholesterol and reduces the fluidity of lipid. The present study not only demonstrates the technical application for monitoring the dynamic molecular behaviors at the interface but also reveals the roles to distinguish lipid molecules on the Abeta-membrane interaction.&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Mouton PR, Chachich ME, Quigley C, Spangler E, Ingram DK. &lt;b&gt;Caloric restriction attenuates amyloid deposition in middle-aged dtg APP/PS1 mice.&lt;/b&gt; &lt;i&gt;Neurosci Lett&lt;/i&gt;. 2009 Oct 30;464(3):184-7. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19699265" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Caloric restriction (CR) mitigates neurological damage arising from aging and a variety of other sources, including neuropathology in young adult mice that express single and double transgenic (tg) mutations associated with Alzheimer disease (AD). To evaluate the potential of CR to protect against relatively heavy AD-type pathology, middle-aged (13-14-month-old) mice that co-express two mutations related to familial AD, amyloid precursor protein (APP) and presenilin 1 (PS1), were fed balanced diets with 40% fewer calories than ad libitum-fed controls. Following 18 weeks of treatment, mice were killed and brains were processed for quantification of total volume of amyloid-beta (Abeta) in the hippocampal formation and the overlying neocortex. Computerized stereology confirmed that CR reduced the total Abeta volume by about one-third compared to that in age-matched controls. Thus, CR appears to attenuate the accumulation of AD-type neuropathology in two cortical brain regions of middle-aged dtg APP/PS1 mice. These findings support the view that CR could be a potentially effective, non-pharmacology strategy for reducing relatively heavy Abeta deposition in older adult dtg APP/PS1 mice, and possibly afford similar protection against the onset and progression of AD in older adult humans.&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Morita M, Osoda K, Yamazaki M, Shirai F, Matsuoka N, Arakawa H, Nishimura S. &lt;b&gt;Effects of non-steroidal anti-inflammatory drugs on Abeta deposition in Abeta(1-42) transgenic C. elegans.&lt;/b&gt; &lt;i&gt;Brain Res&lt;/i&gt;. 2009 Oct 27;1295:186-91. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19666013" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Although epidemiological studies have shown that long-term treatment with non-steroidal anti-inflammatory drugs (NSAIDs) may protect against Alzheimer's disease (AD), the mechanism(s) by which NSAIDs reduce the risk of AD remain to be determined. As C. elegans possess neither inflammatory cells nor the arachidonate cascade, we could evaluate the effects of NSAIDs on amyloid beta (Abeta) deposition in the absence of immune cells using Abeta-transgenic C. elegans. For this purpose, we established a strain of Abeta-transgenic C. elegans in which thioflavin S-reactive deposits are reproducibly detectable by confocal microscopy. Among the NSAIDs examined, ibuprofen and naproxen reduced the number of thioflavin S-reactive deposits. Furthermore, ibuprofen and naproxen neither affect the thioflavin S binding to Abeta nor Abeta expression in transgenic C. elegans. These data suggest that ibuprofen and naproxen, the most frequently used NSAIDs for the treatment of AD, have an inhibitory effect on Abeta deposition that is independent of the arachidonate cascade and cellular immune systems.&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;Kitaguchi H, Tomimoto H, Ihara M, Shibata M, Uemura K, Kalaria RN, Kihara T, Asada-Utsugi M, Kinoshita A, Takahashi R. &lt;b&gt;Chronic cerebral hypoperfusion accelerates amyloid beta deposition in APPSwInd transgenic mice.&lt;/b&gt; &lt;i&gt;Brain Res&lt;/i&gt;. 2009 Oct 19;1294:202-10. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19646974" target="_blank"&gt;PubMed Abstract&lt;/a&gt; &lt;/p&gt;  &lt;p class="MsoNormal"&gt;Chronic cerebral ischemia may accelerate clinicopathological changes in Alzheimer's disease. We have examined whether chronic cerebral hypoperfusion accelerates amyloid beta deposition in amyloid protein precursor transgenic (APP-Tg) mouse. At 5, 8, and 11 months of age, C57Bl/6J male mice overexpressing a mutant form of the human APP bearing the both Swedish (K670N/M671L) and the Indiana (V717F) mutations (APPSwInd) and their litterrmates were subjected to either sham operation or bilateral carotid artery stenosis (BCAS) using microcoils with an internal diameter of 0.18 mm (short-period group). One month after the sham operation or BCAS, these animals were examined by immunohistochemistry for glial fibrillary acidic protein, amyloid beta(1-40) (Abeta(1-40)), amyloid beta(1-42) (Abeta(1-42)), as well as Western blotting and filter assay for Abeta. Another batch of the littermates of APPSwInd mice were subjected to either sham operation or BCAS at 3 months and were examined in the same manner after survival for 9 months (long-period group). In the BCAS-treated group, the white matter was rarefied and astroglia was proliferated. Amyloid beta(1-40) immunoreactivity was found in a few axons in the white matter after BCAS, whereas Abeta(1-42) was accumulated in the scattered cortical neurons and the axons at ages of 6 months and thereafter in the short- and long-period groups. In the neuropil, both Abeta(1-40) and Abeta(1-42) were deposited in the sham-operated and BCAS-treated mice at ages of 9 and 12 months. There were no differences between the short-period group at ages of 12 months and the long-period group. Filter assay showed an increase of Abeta fibrils in the extracellular enriched fraction. Taken together, chronic cerebral hypoperfusion increased Abeta fibrils and induced Abeta deposition in the intracellular compartment and, therefore, may accelerate the pathological changes of Alzheimer's disease.&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;  &lt;p class="MsoNormal"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;div class="blogger-post-footer"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6662563293158062075-5717185379159536075?l=betaamyloid.blogspot.com'/&gt;&lt;/div&gt;&lt;img src="http://feeds.feedburner.com/~r/AmyloidEtal/~4/5uicTtjOI7k" height="1" width="1"/&gt;</description><app:edited xmlns:app="http://www.w3.org/2007/app">2009-10-12T23:15:08.359-07:00</app:edited><thr:total xmlns:thr="http://purl.org/syndication/thread/1.0">0</thr:total><feedburner:origLink>http://betaamyloid.blogspot.com/2009/10/beta-amyloid-deposition-amyloid.html</feedburner:origLink></item><item><title>Amyloid Beta Derived Diffusible Ligand: Beta Amyloid Ligands: Research Papers</title><link>http://feedproxy.google.com/~r/AmyloidEtal/~3/rWGQbuFypoU/amyloid-beta-derived-diffusible-ligand.html</link><author>amyloidorg@gmail.com</author><pubDate>Mon, 12 Oct 2009 23:16:22 PDT</pubDate><guid isPermaLink="false">tag:blogger.com,1999:blog-6662563293158062075.post-5566159203755363290</guid><description>&lt;meta equiv="Content-Type" content="text/html; charset=utf-8"&gt;&lt;meta name="ProgId" content="amyloid beta derived diffusible ligand"&gt;&lt;meta name="Generator" content="amyloid beta derived diffusible ligand"&gt;&lt;meta name="Originator" content="amyloid beta derived diffusible ligand"&gt;&lt;link rel="File-List" href="http://betaamyloid.blogspot.com/2009/10/amyloid-beta-derived-diffusible-ligand.html"&gt;&lt;!--[if gte mso 9]&gt;&lt;xml&gt;  &lt;w:worddocument&gt;   &lt;w:view&gt;Normal&lt;/w:View&gt;   &lt;w:zoom&gt;0&lt;/w:Zoom&gt;   &lt;w:donotoptimizeforbrowser/&gt;  &lt;/w:WordDocument&gt; &lt;/xml&gt;&lt;![endif]--&gt;&lt;style&gt; &lt;!--  /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal 	{mso-style-parent:""; 	margin:0in; 	margin-bottom:.0001pt; 	mso-pagination:widow-orphan; 	font-size:12.0pt; 	font-family:"Times New Roman"; 	mso-fareast-font-family:"Times New Roman";} a:link, span.MsoHyperlink 	{color:blue; 	text-decoration:underline; 	text-underline:single;} a:visited, span.MsoHyperlinkFollowed 	{color:purple; 	text-decoration:underline; 	text-underline:single;} @page Section1 	{size:8.5in 11.0in; 	margin:1.0in 1.25in 1.0in 1.25in; 	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;} --&gt; &lt;/style&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;Amyloid Beta Derived Diffusible Ligand: Beta Amyloid Ligands: Research Papers
&lt;br /&gt;&lt;/p&gt;&lt;p class="MsoNormal" style="text-align: justify;"&gt;
&lt;br /&gt;&lt;/p&gt;&lt;p class="MsoNormal" style="text-align: justify;"&gt;
&lt;br /&gt;&lt;/p&gt;&lt;p class="MsoNormal" style="text-align: justify;"&gt;Sim PL, Heese K. &lt;b&gt;Ligand-Dependent Activation of the Chimeric Tumor Necrosis Factor Receptor-Amyloid Precursor Protein (APP) Reveals Increased APP Processing and Suppressed Neuronal Differentiation.&lt;/b&gt; &lt;i&gt;Neurosignals&lt;/i&gt;. 2009 Sep 29;18(1):9-23. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19786811" target="_blank"&gt;PubMed Abstract&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;The beta-amyloid precursor protein (APP) is a type I transmembrane protein whose functions and metabolic processing have been implicated in the pathogenesis of Alzheimer's disease (AD). APP's physical resemblance as a glycosylated receptor and the presence of several conserved motifs which are characteristics of a membrane-associated receptor has prompted interest to study and understand the role of downstream signaling events mediated by the activation of APP during both physiological and pathological conditions. Efforts to elucidate the mechanisms of APP signaling have not been conclusive. In order to further characterize the intracellular signaling activities of APP, we have constructed a chimeric APP receptor which is made up of the extracellular domain of human tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), the membrane-spanning segment of human APP(770) isoform's beta-cleaved carboxyl-terminal fragment (C99), and the green fluorescent protein (GFP) tagged to the carboxyl-terminus of C99. The mammalian rat pheochromocytoma (PC12) cell line is used as the cellular model for transfection of this TNFRSF1B-APP-GFP (TAF) fusion receptor. Ligand-specific stimulation of this TAF receptor using human recombinant TNF reveals the induction of cytoplasmic TAF phosphorylation on Thr743 (numbering for APP(770) isoform) and an elevated release of APP intracellular domains (AICDs). Time-lapse microscopy shows the trafficking of GFP-tagged AICDs into the nucleus upon TAF receptor activation. The increased presence of AICDs is believed to suppress neuronal differentiation of PC12 cells in response to nerve growth factor treatment, by negatively regulating the levels of p53, cyclin D1 and phosphorylation of the signal transducer and activator of transcription STAT3. Copyright © 2009 S. Karger AG, Basel.&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;Drew SC, Masters CL, Barnham KJ. &lt;b&gt;Alanine-2 carbonyl is an oxygen ligand in Cu2+ coordination of Alzheimer's disease amyloid-beta peptide--relevance to N-terminally truncated forms.&lt;/b&gt; &lt;i&gt;J Am Chem Soc&lt;/i&gt;. 2009 Jul 1;131(25):8760-1. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19496610" target="_blank"&gt;PubMed Abstract&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;Copper interactions with the beta-amyloid peptide (Abeta) are believed to play a role in Alzheimer's disease (AD), in particular due to production of reactive oxygen species and Cu(2+)-mediated oligomerization. To understand the role that copper might play in these processes, a detailed knowledge of the fundamental Cu(2+)/Abeta interactions is essential. To date, the identity of the oxygen ligand(s) involved in Cu(2+) coordination by Abeta has remained unclear. Here, we have used site-specific (13)C and (15)N labeling in conjunction with hyperfine sublevel correlation (HYSCORE) spectroscopy to unambiguously identify the carbonyl of Alanine-2 as an oxygen ligand in one of the pH-dependent Cu(2+) coordination modes of Abeta. Polarization of the carbonyl moiety by Cu(2+) could promote amide hydrolysis and cleavage of the peptide bond between Ala2 and Glu3, providing a chemical mechanism for the generation of truncated Abeta 3-40/42 species found in AD plaques.&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;Aalto S, Scheinin NM, Kemppainen NM, Någren K, Kailajärvi M, Leinonen M, Scheinin M, Rinne JO. &lt;b&gt;Reproducibility of automated simplified voxel-based analysis of PET amyloid ligand [(11)C]PIB uptake using 30-min scanning data.&lt;/b&gt; &lt;i&gt;Eur J Nucl Med Mol Imaging&lt;/i&gt;. 2009 Jun 4; &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19495749" target="_blank"&gt;PubMed Abstract&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;PURPOSE: Positron emission tomography (PET) with 11C-labelled Pittsburgh compound B ([11C]PIB) enables the quantitation of beta-amyloid accumulation in the brain of patients with Alzheimer's disease (AD). Voxel-based image analysis techniques conducted in a standard brain space provide an objective, rapid and fully automated method to analyze [11C]PIB PET data. The purpose of this study was to evaluate both region- and voxel-level reproducibility of automated and simplified [11C]PIB quantitation when using only 30 min of imaging data. METHODS: Six AD patients and four healthy controls were scanned twice with an average interval of 6 weeks. To evaluate the feasibility of short scanning (convenient for AD patients), [11C]PIB uptake was quantitated using 30 min of imaging data (60 to 90 min after tracer injection) for region-to-cerebellum ratio calculations. To evaluate the reproducibility, a test-retest design was used to derive absolute variability (VAR) estimates and intraclass correlation coefficients at both region-of-interest (ROI) and voxel level. RESULTS: The reproducibility both at the region level (VAR 0.9-5.5%) and at the voxel level (VAR 4.2-6.4%) was good to excellent. Based on the variability estimates obtained, power calculations indicated that 90% power to obtain statistically significant difference can be achieved using a sample size of five subjects per group when a 15% change from baseline (increase or decrease) in [11C]PIB accumulation in the frontal cortex is anticipated in one group compared to no change in another group. CONCLUSION: Our results showed that an automated analysis method based on an efficient scanning protocol provides reproducible results for [11C]PIB uptake and appears suitable for PET studies aiming at the quantitation of amyloid accumulation in the brain of AD patients for the evaluation of progression and treatment effects.&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;Johnson AE, Jeppsson F, Sandell J, Wensbo D, Neelissen JA, Juréus A, Ström P, Norman H, Farde L, Svensson SP. &lt;b&gt;AZD2184: a radioligand for sensitive detection of beta-amyloid deposits.&lt;/b&gt; &lt;i&gt;J Neurochem&lt;/i&gt;. 2009 Mar;108(5):1177-86. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=19141073" target="_blank"&gt;PubMed Abstract&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;The presence of beta-amyloid plaques in brain is a hallmark of Alzheimer's disease (AD) and serves as a biomarker for confirmation of diagnosis postmortem. Positron emission tomography (PET) radioligands such as Pittsburgh compound B ([(11)C]-2-(3-fluoro-4-methylamino-phenyl)-benzothiazol-6-ol) (PIB) binds selectively to beta-amyloid and are promising new tools supporting the clinical diagnoses of AD. In addition, such methodology may be useful for evaluation of new drugs aiming at reduction of amyloid plaque load. The objective of this study is to develop a new amyloid selective PET radioligand with higher signal-to-background ratio when compared with existing amyloid PET ligands. The lead compound, AZD2184, (2-[6-(methylamino)pyridin-3-yl]-1,3-benzothiazol-6-ol) was found to have high affinity for amyloid fibrils in vitro (K(d): 8.4 +/- 1.0 nM). Two minutes after i.v. administration in rats, about 1% of the dose was in brain. In vitro autoradiography on cortical brain sections from amyloid-beta precursor protein/presenilin 1 (APP/PS1) mice and AD patients showed that while [(3)H]AZD2184 and [(3)H]PIB are mutually displaceable, [(3)H]AZD2184 displays a higher signal-to-background ratio primarily by virtue of lower background binding levels. The ratio of binding ability in prefrontal cortex (high plaque load) to subcortical white matter (background) was 4.5 for [(3)H]AZD2184 and 0.8 for [(3)H]PIB at 1 nM. In adjacent cortical sections from APP/PS1 mouse as well as from AD cortical tissue, [(3)H]AZD2184 and antibodies to human beta-amyloid labeled identical structures. In vivo administration of [(3)H]AZD2184 to APP/PS1 mice further showed that [(3)H]AZD2184 labels amyloid deposits with low non-specific background binding. Taken together, the pre-clinical profile of AZD2184 in relation to the reference ligand PIB, suggests that (11)C-labeled AZD2184 is a potential radioligand for PET-visualization of beta-amyloid deposits in the living human brain.&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;Koivunen J, Verkkoniemi A, Aalto S, Paetau A, Ahonen JP, Viitanen M, Någren K, Rokka J, Haaparanta M, Kalimo H, Rinne JO. &lt;b&gt;PET amyloid ligand [11C]PIB uptake shows predominantly striatal increase in variant Alzheimer's disease.&lt;/b&gt; &lt;i&gt;Brain&lt;/i&gt;. 2008 Jul;131(Pt 7):1845-53. &lt;a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;dopt=Abstract&amp;amp;list_uids=18583368" target="_blank"&gt;PubMed Abstract&lt;/a&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;Variant Alzheimer's disease (VarAD) with spastic paraparesis and presenile dementia is associated with certain mutations of the presenilin 1 (PS-1) gene, particularly those leading to deletion of exon 9 (PS-1Delta E9). VarAD is neuropathologically characterized by the presence of unusually large, Abeta42 positive, non-cored 'cotton wool' plaques (CWPs), also devoid of dystrophic neurites. The aim of the present study was to find out whether [(11)C]PIB would show increased uptake and serve as an in vivo biomarker of amyloid accumulation in VarAD. A further aim was to assess the correspondence of the [(11)C]PIB binding to the amount and type of Abeta deposits in another group of deceased VarAD patients' brains. We studied four patients with VarAD and eight healthy controls with PET using [(11)C]PIB as tracer. Parametric images were computed by calculating the region-to-cerebellum and region-to-pons ratio in each voxel over 60-90 min. Group differences in [(11)C]PIB uptake were analysed with automated region-of-interest (ROI) analysis. [(11)C]PIB uptake was compared to the immunohistochemically demonstrated deposition of Abeta in the brains of another group of four deceased VarAD patients. Patients with VarAD had significantly higher [(11)C] PIB uptake than the control group in the striatum (caudate nucleus and putamen), anterior and posterior cingulate gyrus, occipital cortex and thalamus. In the caudate and putamen [(11)C]PIB uptake, expressed as region-to-cerebellum ratio, was on the average 43% greater than the mean of the control group. The increases in the anterior (28%) and posterior (27%) cingulate gyrus, occipital cortex (21%) and thalamus (14%) were smaller. All VarAD patients showed this similar topographical pattern of increased [(11)C]PIB uptake. The results were essentially similar when the uptake was expressed as region-to-pons ratios. [(11)C]PIB imaging shows increased uptake in patients with VarAD especially in the striatum, and it can be used to detect amyloid accumulation in vivo in these patients. The pattern of increased [(11)C]PIB uptake is different from that described in sporadic Alzheimer's disease and resembles that seen in Alzheimer's disease patients with certain presenilin-1 mutations or amyloid precursor protein gene duplication showing predominantly striatal increase in [(11)C]PIB uptake.&lt;/p&gt;  &lt;p class="MsoNormal" style="text-align: justify;"&gt;&lt;!--[if !supportEmptyParas]--&gt; &lt;!--[endif]--&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/p&gt; 
&lt;br /&gt;
&lt;br /&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;div class="blogger-post-footer"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6662563293158062075-5566159203755363290?l=betaamyloid.blogspot.com'/&gt;&lt;/div&gt;&lt;img src="http://feeds.feedburner.com/~r/AmyloidEtal/~4/rWGQbuFypoU" height="1" width="1"/&gt;</description><app:edited xmlns:app="http://www.w3.org/2007/app">2009-10-12T23:16:22.811-07:00</app:edited><thr:total xmlns:thr="http://purl.org/syndication/thread/1.0">0</thr:total><feedburner:origLink>http://betaamyloid.blogspot.com/2009/10/amyloid-beta-derived-diffusible-ligand.html</feedburner:origLink></item><item><title>Beta Amyloid Sources, Abeta Peptides Source: Research Paper on Abeta Sources!!!!!!!!!!!!!</title><link>http://feedproxy.google.com/~r/AmyloidEtal/~3/jdhbOY8AxpE/beta-amyloid-sources-abeta-peptides.html</link><author>amyloidorg@gmail.com</author><pubDate>Mon, 12 Oct 2009 23:19:03 PDT</pubDate><guid isPermaLink="false">tag:blogger.com,1999:blog-6662563293158062075.post-4273384095733001333</guid><description>Beta Amyloid Sources, Abeta Peptides Source: Research Paper on Abeta Sources!!!!!!!!!!!!!
&lt;br /&gt;
&lt;br /&gt;Research Papers on Beta amyloid Sources:
&lt;br /&gt;
&lt;br /&gt;Title: Platelets Are the Primary Source of Amyloid β-Peptide in Human Blood
&lt;br /&gt;Authors: Chen M., Inestrosa N. C., Ross G. S. and Fernandez H. L.
&lt;br /&gt;Abstract
&lt;br /&gt;The main component of Alzheimer′s disease (AD) amyloid deposits is amyloid β-peptide (Aβ), a fragment of the larger amyloid precursor protein (APP). The cellular source of Aβ is not known, but a circulatory origin has been postulated. We studied human blood from healthy individuals and found that platelets account for almost 90% of the total anti-Aβ immunoreactivity detected in whole blood. Using reverse-phase HPLC, we identified a platelet peptide which corresponds to Aβ by three criteria. (a) it shares a retention time with the synthetic Aβ1-40 peptide in two consecutive HPLC tests; (b) it interacts with two anti-Aβ antibodies in separate ELISAs; and, (c) its partial N-terminal amino acid sequence closely matches that of Aβ. The detection of this peptide in platelets indicates that, aside from the well-known non-amyloidogenic (secretory) pathway, the processing of APP in platelets from healthy individuals also involves an amyloidogenic pathway. These findings are consistent with the view that platelets are one of the major sources of Aβ in the circulation.
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&lt;br /&gt;Title: In vitro expression analysis shows that the secretory form of gelsolin is the sole source of amyloid in gelsolin-related amyloidosis
&lt;br /&gt;Authors: H Kangas, T Paunio, N Kalkkinen, A Jalanko and L Peltonen
&lt;br /&gt;
&lt;br /&gt;Abstract
&lt;br /&gt;Amyloidoses are a group of diseases where abnormal fibrillar protein deposits accumulate in patients' tissues. In familial amyloidosis of the Finnish type (FAF), or gelsolin-related amyloidosis, the amyloid subunit protein consists of gelsolin peptides of amino acids 173-243 with the disease causing substitution at Asp187. Gelsolin is an actin- modulating protein and exists in both secretory and intracellular forms both encoded by a single gene in chromosome 9. We have previously shown that the FAF-associated forms of secretory gelsolin carrying the Asp187Asn or Asp187Tyr mutations are abnormally processed in cells, resulting in the secretion of an aberrant 68 kDa carboxyterminal fragment. Here we demonstrate by N-terminal sequencing that the amino terminus of this abnormal fragment is the amino acid 173 and thus represents the N-terminus of the FAF amyloid. We also provide evidence that the same truncated gelsolin can be found among the aberrant gelsolin fragments detected in patients' CSF. Finally, we also expressed the FAF-associated forms of intracellular gelsolin in COS-1 cells, and found no abnormality in their processing opposite to secretory form. Our results provide strong evidence that the secretory gelsolin is solely responsible for the amyloid formation in FAF.
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&lt;br /&gt;Title: Alzheimer’s amyloid peptide as a source of neurotoxic free radicals: the role of structural effects
&lt;br /&gt;
&lt;br /&gt;Author: Dariusz Pogocki
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;Abstract.
&lt;br /&gt;
&lt;br /&gt;This mini review gives a brief overview over the oxidation
&lt;br /&gt;mechanism of methionine (Met), relevant for processes which may lead to the
&lt;br /&gt;oxidation of amyloid -Beta peptide (BetaAP), involved in the pathogenesis of
&lt;br /&gt;Alzheimer’s disease. The CuII-catalysed oxidation of C-terminal Met35 in BetaAP
&lt;br /&gt;depends on the secondary structure of the peptide. That seems to be the key to
&lt;br /&gt;the known propensities of this peptide to form reactive oxygen species and
&lt;br /&gt;free radicals. The pro-oxidant character of BetaAP is not associated with its
&lt;br /&gt;Beta-sheet insoluble form. On the contrary, the alpha-helically organised structure is responsible for BetaAP redox-related cytotoxicity.
&lt;br /&gt;
&lt;br /&gt;Title: Identification of full length β-amyloid precursor protein in human neuronal and non-neuronal cell culture supernatant: a possible extracellular source for the generation of Aβ
&lt;br /&gt;
&lt;br /&gt;Authors: Kelly J. Conn a;  Gregoris Papastoitsis b;  Barbara Meckelein a; Carmela R. Abraham a
&lt;br /&gt;Abstract
&lt;br /&gt;β protein (Aβ) which is deposited in the amyloid plaques and vasculature in brains of Alzheimer's Disease (AD) patients is a 39 to 43 amino acid peptide proteolytically derived from the amyloid precursor protein (AβPP). Three major isoforms are expressed in the brain: AβPP751 and AβPP770 which contain a Kunitz-like protease inhibitor domain (KPI), and AβPP695 To date it is still unknown which AβPP isoforms are the precursors of Aβ, which proteolytic pathways are involved in its production, and if the processing occurs intracellularly and/or extracellularly. We now report the identification, by Western blot analysis, of an Aβ-containing AβPP protein which co-migrates with full length recombinant AβPP751 in the culture supernatant of two human neuroblastoma cell lines and in one human kidney cell line. This protein is recognized with six different antibodies towards AβPP targeting intracellular, extracel lular, and the Aβ region of AβPP. The immunodetection of this Aβ precursor is shown to be specific by absorption. The presence of full length AβPP in culture supernatant strongly suggests that some processing of ApPP may occur extracellularly. The recent identification of two soluble and/ or secreted proteases from AD and monkey brain both capable of processing recombinant AβPP in vitro1,2 suggests that Aβ production may occur extracellularly in vivo by an undescribed mechanism.
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;Chondrocyte of rheumatoid arthritis serve as a source of intra-articular acute-phase serum amyloid A protein
&lt;br /&gt;Authors: Shigeki Momohara Hiroshi Okamoto and Hisashi Yamanaka
&lt;br /&gt;Abstract: Article Outline  
&lt;br /&gt;Title: On the uniform source of amyloid in plaques, tangles and vascular deposits
&lt;br /&gt;Authors: D. Carleton Gajdusek
&lt;br /&gt;Abstract
&lt;br /&gt;A series of recent studies involving isolation, sequencing and cloning of a precursor protein of amyloid of AD, as well as in aging and Guamanian ALS/PD confirms the unifying hypothesis that the amyloid of paired helical filaments, amyloid plaque cores and vascular amyloid are of one source. The gene for the precursor protein of this brain amyloid is on chromosome 21.
&lt;br /&gt;
&lt;br /&gt;&lt;meta equiv="Content-Type" content="text/html; charset=utf-8"&gt;&lt;meta name="ProgId" content="beta amyloid sources"&gt;&lt;meta name="Generator" content="beta amyloid sources"&gt;&lt;meta name="Originator" content="beta amyloid sources"&gt;&lt;link rel="File-List" href="http://betaamyloid.blogspot.com/2009/10/beta-amyloid-sources-abeta-peptides.html"&gt;&lt;!--[if gte mso 9]&gt;&lt;xml&gt;  &lt;w:worddocument&gt;   &lt;w:view&gt;Normal&lt;/w:View&gt;   &lt;w:zoom&gt;0&lt;/w:Zoom&gt;   &lt;w:donotoptimizeforbrowser/&gt;  &lt;/w:WordDocument&gt; &lt;/xml&gt;&lt;![endif]--&gt;&lt;style&gt; &lt;!--  /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal 	{mso-style-parent:""; 	margin:0in; 	margin-bottom:.0001pt; 	mso-pagination:widow-orphan; 	font-size:12.0pt; 	font-family:"Times New Roman"; 	mso-fareast-font-family:"Times New Roman";} h3 	{margin-right:0in; 	mso-margin-top-alt:auto; 	mso-margin-bottom-alt:auto; 	margin-left:0in; 	mso-pagination:widow-orphan; 	mso-outline-level:3; 	font-size:13.5pt; 	font-family:"Times New Roman"; 	font-weight:bold;} a:link, span.MsoHyperlink 	{color:blue; 	text-decoration:underline; 	text-underline:single;} a:visited, span.MsoHyperlinkFollowed 	{color:purple; 	text-decoration:underline; 	text-underline:single;} p 	{margin-right:0in; 	mso-margin-top-alt:auto; 	mso-margin-bottom-alt:auto; 	margin-left:0in; 	mso-pagination:widow-orphan; 	font-size:12.0pt; 	font-family:"Times New Roman"; 	mso-fareast-font-family:"Times New Roman";} @page Section1 	{size:8.5in 11.0in; 	margin:1.0in 1.25in 1.0in 1.25in; 	mso-header-margin:.5in; 	mso-footer-margin:.5in; 	mso-paper-source:0;} div.Section1 	{page:Section1;} --&gt; &lt;/style&gt;  &lt;p style="text-align: justify;"&gt;Source: &lt;a href="http://www.ncbi.nlm.nih.gov/"&gt;PubMed&lt;/a&gt;&lt;/p&gt;  &lt;p style="text-align: justify;"&gt;&lt;strong&gt;&lt;span style="font-size: 10pt; font-family: Arial; font-weight: normal;"&gt;
&lt;br /&gt;&lt;o:p&gt;&lt;/o:p&gt;&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt; 
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&lt;br /&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;div class="blogger-post-footer"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6662563293158062075-4273384095733001333?l=betaamyloid.blogspot.com'/&gt;&lt;/div&gt;&lt;img src="http://feeds.feedburner.com/~r/AmyloidEtal/~4/jdhbOY8AxpE" height="1" width="1"/&gt;</description><app:edited xmlns:app="http://www.w3.org/2007/app">2009-10-12T23:19:03.768-07:00</app:edited><thr:total xmlns:thr="http://purl.org/syndication/thread/1.0">0</thr:total><feedburner:origLink>http://betaamyloid.blogspot.com/2009/10/beta-amyloid-sources-abeta-peptides.html</feedburner:origLink></item><item><title>Beta Amyloid Peptide Synthesis, Amyloid Synthesis: Research Paper on Beta Amyloid Synthesis</title><link>http://feedproxy.google.com/~r/AmyloidEtal/~3/uB-ybYbFDjg/beta-amyloid-peptide-synthesis-amyloid.html</link><author>amyloidorg@gmail.com</author><pubDate>Mon, 12 Oct 2009 23:20:21 PDT</pubDate><guid isPermaLink="false">tag:blogger.com,1999:blog-6662563293158062075.post-4476592558406822814</guid><description>Beta Amyloid Peptide Synthesis, Amyloid Synthesis: Research Paper on Beta Amyloid Synthesis!!!!!!!!!!!
&lt;br /&gt;
&lt;br /&gt;Title: Synthesis of beta-amyloid fragment 5RHDSGY10 and its isomers
&lt;br /&gt;
&lt;br /&gt;Authors:
&lt;br /&gt;Aleshina EIu, Pyndyk NV, Moĭsa AA, Sanzhakov MA, Kharybin ON, Nikolaev EN, Kolesanova EF.
&lt;br /&gt;
&lt;br /&gt;Abstract:
&lt;br /&gt;Peptide RHDSGY that represents the fragment of human beta-amyloid Zn-binding site and its isomers RH(D-Asp)SGY and RH(beta-Asp)SGY have been prepared by solid-phase synthesis and analysed by HPLC and various mass-spectrometric methods. The problem of low yield of peptide RHDSGY and its isomers attributed to 9-fluorenylmethoxycarbonyl (Fmoc)-amino acids and/or formation of side-products as RH(Asp-imide)SGY and RHDSGY (instead of RH(beta-Asp)SGY) was solved via selection of reagents for the removal of Fmoc groups from the growing peptide chain.
&lt;br /&gt;
&lt;br /&gt;Title:	
&lt;br /&gt;Synthesis of of beta-amyloid precursor peptide and presenilin segments.
&lt;br /&gt;
&lt;br /&gt;Authors:
&lt;br /&gt;Baláspiri L, Langel U.
&lt;br /&gt;
&lt;br /&gt;Abstract:
&lt;br /&gt;It seems likely that the beta-amyloid precursor protein (APP) and the presenilins (PS-1/2) play important roles in the development of Alzheimer's disease (AD). Attempts to mimic the biochemical actions of these proteins are often made by the application of fragments of these proteins. However, the synthesis of these segments by conventional methods of peptide synthesis is problematic. We have synthesized several C-terminal fragments of APP and PS-1/2 by solid-phase synthesis through combination of automatic and manual methods of synthesis. This permits solution of the 'difficult sequences' in the solid-phase synthesis of these peptides. Some details of the syntheses of nine segments are presented in this paper.
&lt;br /&gt;
&lt;br /&gt;Title:
&lt;br /&gt;Synthesis and activity of fibrillogenesis peptide inhibitors related to the 17-21 beta-amyloid sequence.
&lt;br /&gt;
&lt;br /&gt;Authors:
&lt;br /&gt;Giordano C, Masi A, Pizzini A, Sansone A, Consalvi V, Chiaraluce R, Lucente G.
&lt;br /&gt;
&lt;br /&gt;Abstract:
&lt;br /&gt;Peptide derivatives 1-5, incorporating synthetic non-proteinogenic amino acids, related to the beta-amyloid 17-21 fragment of the amyloidogenic Abeta(1-40), and the N-protected decapeptide 6, corresponding to a dimeric sequence of the same fragment, have been synthesized. These compounds were designed by using Soto's pentapeptide Ac-LPFFD-NH(2) (iAbeta5p) as lead compound. Their activity as inhibitors of fibrillogenesis and stability against enzymatic degradation have been determined. Compounds 1, 5 and 6 are potent inhibitors in comparison to the lead compound. Exposure to chymotrypsin of peptide derivatives 1-5, all containing unnatural amino acids, shows increased stability as compared with iAbeta5p and 6. Conformational properties of the new compounds have been determined by CD and FT-IR spectroscopies.
&lt;br /&gt;
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&lt;br /&gt;&lt;div class="blogger-post-footer"&gt;&lt;a href="http://feedburner.google.com/fb/a/mailverify?uri=AmyloidEtal&amp;amp;loc=en_US"&gt;Subscribe to Amyloid et.al. by Email&lt;/a&gt;&lt;img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6662563293158062075-4476592558406822814?l=betaamyloid.blogspot.com'/&gt;&lt;/div&gt;&lt;img src="http://feeds.feedburner.com/~r/AmyloidEtal/~4/uB-ybYbFDjg" height="1" width="1"/&gt;</description><app:edited xmlns:app="http://www.w3.org/2007/app">2009-10-12T23:20:21.514-07:00</app:edited><thr:total xmlns:thr="http://purl.org/syndication/thread/1.0">0</thr:total><feedburner:origLink>http://betaamyloid.blogspot.com/2009/10/beta-amyloid-peptide-synthesis-amyloid.html</feedburner:origLink></item><item><title>Beta Amyloid Elisa: Serum Amyloid a Elisa: Amyloid Elisa: Research Papers</title><link>http://feedproxy.google.com/~r/AmyloidEtal/~3/Oattx-Hm4bM/beta-amyloid-elisa-kits-abeta-elisa.html</link><author>amyloidorg@gmail.com</author><pubDate>Wed, 07 Oct 2009 09:30:24 PDT</pubDate><guid isPermaLink="false">tag:blogger.com,1999:blog-6662563293158062075.post-7749735256663229846</guid><description>Beta Amyloid Elisa: Serum Amyloid a Elisa: Amyloid Elisa: Research Papers&lt;br /&gt;Title: &lt;br /&gt;ELISA analysis of [beta]-secretase cleavage of the Swedish amyloid precursor protein in the secretory and endocytic pathways.&lt;br /&gt;&lt;br /&gt;Authors:&lt;br /&gt;Steinhilb, Michelle L 1; Turner, R. Scott 2; Gaut, James R 3&lt;br /&gt;&lt;br /&gt;Abstract:&lt;br /&gt;Limiting beta amyloid (A[beta]) production could become an important therapeutic target in Alzheimer's disease (AD). A[beta] is derived by the sequential cleavage of amyloid precursor protein (APP) by [beta]- and [gamma]-secretases. A double missense mutation in APP found in a Swedish pedigree (APPsw) elevates A[beta]40 and A[beta]42 production. A[beta] production and, therefore, [beta]-secretase cleavage of APPsw reportedly occur in the endoplasmic reticulum (ER), Golgi and endocytic compartments. However, the relative contribution of [beta]-secretase cleavage occurring in each compartment has not been determined. Experiments described here use a novel ELISA to measure the [beta]-cleaved product, APPsw[beta]. Using this ELISA, we provide new information regarding the relative amount of [beta]-secretase cleavage of APPsw that occurs in secretory and endocytic pathways. Using a dilysine retrieval motif to retain APPsw in the ER, we discovered that less than 15% of the [beta]-secretase cleavage was still detected. Experiments utilizing endocytosis-impaired mutants of APPsw revealed that little or no [beta]-secretase cleavage of APPsw appears to take place through endocytosis. Surprisingly, deletion of the entire cytoplasmic tail increased both APPsw[beta] and A[beta] secretion, suggesting that protein interactions with this region normally impede [beta]-secretase cleavage. These results suggest that APPsw is cleaved by [beta]-secretase late in the secretory pathway.&lt;br /&gt;&lt;br /&gt;Title: &lt;br /&gt;ELISA method for measurement of amyloid-beta levels.&lt;br /&gt;&lt;br /&gt;Authors: &lt;br /&gt;Schmidt SD, Nixon RA, Mathews PM.&lt;br /&gt;&lt;br /&gt;Abstract:&lt;br /&gt;The neuritic plaque in the brain of Alzheimer's disease (AD) patients consists of an amyloid composed primarily of Abeta, an approx 4-kDa peptide derived from the amyloid precursor protein. Multiple lines of evidence suggest that Abeta plays a key role in the pathogenesis of the disease, and potential treatments that target Abeta production and/or Abeta accumulation in the brain as beta-amyloid are being aggressively pursued. Methods to quantitate the Abeta peptide are, therefore, invaluable to most studies aimed at a better understanding of the molecular etiology of the disease and in assessing potential therapeutics. Although other techniques have been used to measure Abeta in the brains of AD patients and beta-amyloid-depositing transgenic mice, the enzyme-linked immunosorbent assay (ELISA) is one of the most commonly used, reliable, and sensitive methods for quantitating the Abeta peptide. Here we describe methods for the recovery of both soluble and deposited Abeta from brain tissue and the subsequent quantitation of the peptide by sandwich ELISA.&lt;br /&gt;&lt;br /&gt;Title: &lt;br /&gt;Determination of amyloid beta protein precursors harboring active form of proteinase inhibitor domains in cerebrospinal fluid of Alzheimer's disease patients by trypsin-antibody sandwich ELISA.&lt;br /&gt;    &lt;br /&gt;Authors: Kitaguchi N, Tokushima Y, Oishi K, Takahashi Y, Shiojiri S, Nakamura S, Tanaka S, Kodaira R, Ito H.&lt;br /&gt;&lt;br /&gt;Abstract:&lt;br /&gt;beta-Amyloid protein precursors (APP) having proteinase inhibitor domains (APPI) were quantified by a new sandwich enzyme linked immunosorbent assay for detection of active (free) form of proteinase inhibitors by using trypsin in place of the first antibody and by denaturation of APPI-trypsin complex in the microtiterplate. The concentration of APPs having APPI in cerebrospinal fluid of Alzheimer's disease patients was found, by this method, to be significantly elevated compared with those of multi-infarct dementia.&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;    &lt;br /&gt;&lt;br /&gt;Title:&lt;br /&gt;Development of a specific ELISA for the quantitative study of amino-terminally truncated beta-amyloid peptides&lt;br /&gt;&lt;br /&gt;Authors:&lt;br /&gt;Mohammed El Mouedden, Marc Vandermeeren, Theo Meert and Marc MerckenCorresponding Author Contact Information, &lt;br /&gt;&lt;br /&gt;Abstract:&lt;br /&gt;Clinical studies for disease modifying drugs in Alzheimer's disease are in real need for a sensitive biochemical diagnostic and therapeutic marker. Encouraging results have been obtained by measuring levels of pathology related proteins such as amyloid beta (Aβ) peptides and tau proteins in cerebrospinal fluid (CSF) and plasma of patients. We and other research groups have shown that truncated Aβ11–40 and Aβ11–42 is also a potential marker and that it is produced and deposited in the brains of patients and transgenic mouse models. Because of a lack of quantitative methods for specific measurement of the truncated Aβ it has not been possible to evaluate the true value of this potential biomarker. To overcome these limitations we developed a novel monoclonal antibody-based sandwich enzyme-linked immunosorbent assay (ELISA) to measure Aβ11–40 and Aβ11–42 levels in biological materials. For this purpose monoclonal antibodies were produced that react specifically with amyloid precursor protein (APP) products generated by cleavage at position 11 of the Aβ sequence. The assay has the sensitivity, selectivity and dynamic range to allow specific, direct quantitation of truncated Aβ11 peptides in cell culture medium, cerebrospinal fluid and brain tissue extracts.&lt;br /&gt;&lt;br /&gt;&lt;br /&gt;Title: &lt;br /&gt;Sensitive ELISA detection of amyloid-[beta] protofibrils in biological samples.&lt;br /&gt;&lt;br /&gt;Authors:&lt;br /&gt;Englund, Hillevi; Sehlin, Dag ; Johansson, Ann-Sofi ; Nilsson, Lars N. G. ; Gellerfors, Par ; Paulie, Staffan ; Lannfelt, Lars ; Pettersson, Frida Ekholm &lt;br /&gt;&lt;br /&gt;Abstract:&lt;br /&gt;Amyloid-[beta] (A[beta]) protofibrils are known intermediates of the in vitro A[beta] aggregation process and the protofibrillogenic Arctic mutation (APPE693G) provides clinical support for a pathogenic role of A[beta] protofibrils in Alzheimer's disease (AD). To verify their in vivo relevance and to establish a quantitative A[beta] protofibril immunoassay, A[beta] conformation dependent monoclonal antibodies were generated. One of these antibodies, mAb158 (IgG2a), was used in a sandwich ELISA to specifically detect picomolar concentrations of A[beta] protofibrils without interference from A[beta] monomers or the amyloid precursor protein (APP). The specificity and biological significance of this ELISA was demonstrated using cell cultures and transgenic mouse models expressing human APP containing the Swedish mutation (APPKN670/671ML), or the Swedish and Arctic mutation in combination. The mAb158 sandwich ELISA analysis revealed presence of A[beta] protofibrils in both cell and animal models, proving that A[beta] protofibrils are formed not only in vitro, but also in vivo. Furthermore, elevated A[beta] protofibril levels in the Arctic-Swedish samples emphasize the usefulness of the Arctic mutation as a model of enhanced protofibril formation. This assay provides a novel tool for investigating the role of A[beta] protofibrils in AD and has the potential of becoming an important diagnostic assay.&lt;br /&gt;&lt;br /&gt;Title: Diagnostic Accuracy of ELISA and xMAP Technology for Analysis of Amyloid ß42 and Tau Proteins&lt;br /&gt;Authors: Thierry S.M. Reijn, Marcel Olde Rikkert, Wieneke J.A. van Geel, Danielle de Jong and Marcel M. Verbeek&lt;br /&gt;&lt;br /&gt;Abstract:&lt;br /&gt;&lt;br /&gt;Background: Cerebrospinal fluid (CSF) concentrations of amyloid ß42 (Aß42) peptides and tau proteins may serve as biomarkers for Alzheimer disease (AD). Recently, the xMAP technology has been introduced as an alternative to ELISA for measurement of these markers.&lt;br /&gt;&lt;br /&gt;Methods: We used xMAP assays and ELISA to analyze CSF concentrations of Aß42, total tau (t-tau), and tau phosphorylated at threonine 181 (p-tau181) in samples from 69 patients with Alzheimer disease, 26 patients with vascular dementia, and 55 controls without neurological disorders.&lt;br /&gt;&lt;br /&gt;Results: High CV values (&gt;28%) for the ratio of xMAP:ELISA were observ
