ALN Magazine

Bulk Size Autoclaves

ALN Magazine news desk — Wed, 11 Nov 2009 12:00:00 -0500

In today’s economic environment, it’s critical that facilities utilize resources and space as efficiently as possible. And since an autoclave vessel can last more than 20 years, it’s important to ensure that the right long term choices are being made for your facility.

Management Tip #46: The 10 Essentials of Delegating

ALN Magazine news desk — Wed, 11 Nov 2009 12:00:00 -0500

You will not be an effective manager unless you learn how to delegate. The question, "Should I be handling this?" must be asked frequently if you are to develop your associates, build a strong team, and avoid being swamped.

Organ Regeneration in Zebrafish

ALN Magazine news desk — Wed, 11 Nov 2009 12:00:00 -0500

Researchers at the Salk Institute for Biological Studies have identified an essential cellular pathway in zebrafish that paves the way for limb regeneration.

Antioxidants May Be Influenza's Achilles Heel

ALN Magazine news desk — Wed, 11 Nov 2009 12:00:00 -0500

A team of researchers studying frogs have raised hopes that they have found an Achilles' heel for all strains of the flu — antioxidants.

Stroke Drug Could Help Cure Cancer

ALN Magazine news desk — Wed, 11 Nov 2009 12:00:00 -0500

Israeli scientists studying mice have identified a substance that can kill cancerous cells without harming healthy ones, paving the way for more effective cancer treatment.

Diabetic Fruit Flies Created

ALN Magazine news desk — Wed, 11 Nov 2009 12:00:00 -0500

Medical researchers at the University of Maryland have created fruit fly models of diabetes to study the genetics involved in the disease.

Commissioning a Biocontainment Facility for Accreditation/Certification

ALN Magazine news desk — Wed, 04 Nov 2009 12:00:00 -0500

Whether your project is a new building or a small renovation, a diagnostics lab or a high-containment animal research facility, the process of commissioning can become an integral tool in support of applications required for many accreditation and certification organizations.

Management Tip #45: How to Raise Your Visibility at Work

ALN Magazine news desk — Wed, 04 Nov 2009 12:00:00 -0500

Used to flying below the radar at work? Think not being noticed will keep your job safe? Not anymore. The best strategy now is to figure out how you can raise your visibility at work — in positive ways.

Kent State to Provide BSL3 and 4 Training

ALN Magazine news desk — Wed, 04 Nov 2009 12:00:00 -0500

University officials announced that Kent State has been selected as the second facility in the country to provide continuing education to professionals working in BSL3 and 4 laboratories.

Cancer Patient Radiation Treatments Made Safer

ALN Magazine news desk — Wed, 04 Nov 2009 12:00:00 -0500

In experiments with mice, U.S. researchers say they may have found a way to protect healthy tissue and also increase tumor death when cancer patients undergo radiation therapy.

Mole Rat May Aid Human Health

ALN Magazine news desk — Wed, 04 Nov 2009 12:00:00 -0500

Mice are very prone to cancer. People have stronger defenses against cancer, the disease accounts for 23 percent of human mortality. But the mole rat seems not to get the disease at all.

Probiotic Therapy Helps Recovery from Colitis

ALN Magazine news desk — Wed, 04 Nov 2009 12:00:00 -0500

A new study has found that the probiotic, Bacillus polyfermenticus, can help mice recover from colitis. Ulcerative colitis and Crohn's disease are the two major types of Inflammatory Bowel Disease (IBD).

JAX Publishes Online Tool for Exploring Autoimmune Disease Gene Networks

ALN Magazine news desk — Wed, 04 Nov 2009 12:00:00 -0500

The Jackson Laboratory publishes a new tool to accelerate discovery of autoimmune disease mechanisms and therapies.

Facebook for Scientists

ALN Magazine news desk — Wed, 28 Oct 2009 12:00:00 -0500

A two–year, $12.2 million NIH grant will help scientists find research partners more easily, thanks to a Facebook-like professional social network called VIVOweb. By fostering alliances, it is hoped that biomedical research and discovery will move faster.

Management Tip #44: A Practical Guide for Developing Leaders

ALN Magazine news desk — Wed, 28 Oct 2009 12:00:00 -0500

Here's a practical guide for developing leaders, adapted from June Delano with Monitor Executive Development. While the guide does not include everything a leader needs to learn, it does offer ideas for developing people before and during new leadership assignments.

Mice Regain Ability to Extend Telomeres

ALN Magazine news desk — Wed, 28 Oct 2009 12:00:00 -0500

Mice and Dyskeratosis Congenita patients share a genetic deficiency that shortens their telomeres; studying how the mice recover normal telomere length suggests potential for DKC therapy.

Symptoms of Depression Appear in Mice Exposed to Light at Night

ALN Magazine news desk — Wed, 28 Oct 2009 12:00:00 -0500

Researchers found that too much light at night can lead to symptoms of depression, according to a new study in mice.

Retardation Tied to Brain Protein

ALN Magazine news desk — Wed, 28 Oct 2009 12:00:00 -0500

In a study with mice researchers have gained new insight into how a brain protein growth factor could lead to mental retardation.

Bedding Out, Bedding In

ALN Magazine news desk — Wed, 21 Oct 2009 12:00:00 -0500

Many bedding disposal and dispensing products offer distinct advantages to save animal facilities both time and money. If your laboratory is still dumping out soiled bedding into a garbage can and replacing it by scooping from a bag, it may be time to think about improving your methods. Consider the benefits to your laboratory’s workflow, ergonomics, and cleanliness by upgrading your systems for bedding disposal and dispensing.

Management Tip #43: What Great Managers Do Differently

ALN Magazine news desk — Wed, 21 Oct 2009 12:00:00 -0500

Great managers break every rule perceived as “conventional wisdom,” when dealing with the selection, motivation, and development of staff.

Study with Monkeys Shows Promise for Parkinson's

ALN Magazine news desk — Wed, 21 Oct 2009 12:00:00 -0500

Researchers studying Macaque monkeys, that received gene therapy for symptoms of Parkinson's disease, saw a significant improvement in their motor function without the side effects associated with current standard therapy.

Finding Sheds New Light on Colon Cancer Prevention

ALN Magazine news desk — Wed, 21 Oct 2009 12:00:00 -0500

University of Florida researchers have grown tumors in mice using cells from inflamed but noncancerous colon tissue taken from human patients, a finding that sheds new light on colon cancer and how it might be prevented.

Drugs to Save Vision May Temporarily Break the Blood-retina Barrier

ALN Magazine news desk — Wed, 21 Oct 2009 12:00:00 -0500

Drugs to save vision might one day be delivered more safely by temporarily breaking through the blood-retina barrier, which normally prevents molecules in the blood from reaching the retina.

UGA College of Veterinary Medicine Hosts Symposium

ALN Magazine news desk — Wed, 21 Oct 2009 12:00:00 -0500

The University of Georgia, College of Veterinary Medicine will host the Science of Veterinary Medicine Research Day Symposium on Thursday, Oct. 29. Admission is free and the symposium is open to the public. UGA veterinary students who participate in the symposium can receive elective course credit.

Design Considerations for Mouse Holding Rooms

ALN Magazine news desk — Wed, 14 Oct 2009 12:00:00 -0500

This article is presented with the intention of stimulating continued thought and dialogue regarding the process of design of mouse animal holding rooms and how to best serve the parties of interest.

Management Tip #42: Top Ten Reasons to Quit Your Job

ALN Magazine news desk — Wed, 14 Oct 2009 12:00:00 -0500

Susan Heathfield, a management and organization development consultant with about.com offers these top ten reasons why you might want to quit your current job.

Fighting Osteoporosis? Grow New Bones

ALN Magazine news desk — Wed, 14 Oct 2009 12:00:00 -0500

A new mechanism of bone formation in mice has been discovered that works without inducing the complementary bone breakdown.

Function of Immune Cells Changed by Prostate Tumors

ALN Magazine news desk — Wed, 14 Oct 2009 12:00:00 -0500

Researchers have learned that prostate tumors in mice can cause immune cells to change their function. This finding has important implications for the design of immune-based therapies for cancer.

Fountain of Youth - Fact or Fiction

ALN Magazine news desk — Wed, 14 Oct 2009 12:00:00 -0500

A report in Agence France-Presse suggests that the fountain of youth may exist after all. Scientists have discovered means to extend the lifespan of mice suggesting that aging and age-related diseases can be treated.

Sleepless Nights for Mice Linked to Alzheimer’s Plaques

ALN Magazine news desk — Wed, 14 Oct 2009 12:00:00 -0500

A new study suggests that sleep problems may actually contribute to the disease process. Researchers report that disrupted sleep can lead to the buildup of brain plaques — a hallmark of Alzheimer's disease — in mice.

NIH Announces Awards to Encourage High-Risk Research and Innovation

ALN Magazine news desk — Wed, 07 Oct 2009 12:00:00 -0500

NIH recently announced awards with funding of $348 million over five years to encourage exploration of ideas that have the potential to speed the translation of research into improved health.

Management Tip #41: Uncertainty Can Be More Stressful Than Clear Negative Feedback

ALN Magazine news desk — Wed, 07 Oct 2009 12:00:00 -0500

Some individuals would rather receive clear negative information than deal with ambiguity or uncertainty, according to new research out of the University of Toronto.

ALN Subscription Offer Raises Money for ResearchSaves Campaign

ALN Magazine news desk — Wed, 07 Oct 2009 12:00:00 -0500

The Foundation for Biomedical Research (FBR) announced it has launched a national animal research education campaign. Please join us in keeping public opinion on the importance of humane animal research enlightened and strong. Your free subscription to ALN Magazine can help.

Pharmacal Research Laboratories Inc Awarded Vendor of the Year

ALN Magazine news desk — Wed, 07 Oct 2009 12:00:00 -0500

The New Jersey Branch of AALAS offers its Vendor of the Year Award to an outstanding vendor who is active in the New Jersey AALAS branch and who serves the industry.

Mouse Model Mimics Humans

ALN Magazine news desk — Wed, 07 Oct 2009 12:00:00 -0500

Researcher’s goal — to create a mouse model that mimics the natural progression of cancer in humans, to provide advances in the field of melanoma preclinical science.

Drug Crosses Blood-Brain Barrier Reducing Formation of Brain Metastases in Mice

ALN Magazine news desk — Wed, 07 Oct 2009 12:00:00 -0500

According to a new study, the drug vorinostat is able to cross the blood-brain barrier and reduce the development of large metastatic tumors in mice.

A Chemical Treatment System for Liquid Effluent

ALN Magazine news desk — Wed, 30 Sep 2009 12:00:00 -0500

A waste treatment system was designed and built to process liquid effluent from a laboratory/vivarium working with human pathogenic viruses.

Management Tip #40: Eight Tips to Encourage Meaningful Work Conflict

ALN Magazine news desk — Wed, 30 Sep 2009 12:00:00 -0500

Susan M. Healthfield from about.com offers eight useufl tips to healthy conflict in the workplace.

Immune Cells Could Heal Injured Lungs

ALN Magazine news desk — Wed, 30 Sep 2009 12:00:00 -0500

New research with mice is shedding light on how a special group of immune cells heal badly injured lungs. The next step is to find a way to boost the cells in patients or get them to work harder when needed.

Mice Provide Weight Loss Hope

ALN Magazine news desk — Wed, 30 Sep 2009 12:00:00 -0500

A group of mice genetically engineered to alter the action of a gene called Cpe experienced a reduction in appetite, but their metabolism remained high despite being less hungry and not eating as much as normal mice.

Paralyzed Rats Walk Again

ALN Magazine news desk — Wed, 30 Sep 2009 12:00:00 -0500

An experiment that has helped paralyzed rats to walk again has raised new hopes for patients with spinal cord injury.

Two Monkeys Now Able to See in Color

ALN Magazine news desk — Wed, 30 Sep 2009 12:00:00 -0500

Dalton and Sam are male squirrel monkeys, about a foot tall. Recently, they were endowed with a new genetic gift— the ability to see the world with full color vision.

Alzheimer's Research Shows Immune Response to Vaccine

ALN Magazine news desk — Wed, 30 Sep 2009 12:00:00 -0500

A researcher working on a vaccine for Alzheimer's disease (AD) has demonstrated that it is possible to test and measure specific immune responses in mice carrying human genes and to anticipate the immune response in Alzheimer's patients.

Management Education for Laboratory Animal Facility Managers

ALN Magazine news desk — Wed, 23 Sep 2009 12:00:00 -0500

Individuals willing to study and apply new skills can take advantage of the many programs available for professional development.

Management Tip #39: Lead Through Listening

ALN Magazine news desk — Wed, 23 Sep 2009 12:00:00 -0500

As a business leader, you have to listen, get the facts, determine the problem, and help resolve the situation.

Green Vivaruim Foundation Announces Call for Nominations

ALN Magazine news desk — Wed, 23 Sep 2009 12:00:00 -0500

The Green Vivarium Foundation will be hosting their 2nd Annual Green Vivarium Foundation awards at AALAS.

Simple Solutions for Effective Cleaning and Sterilization Inside Your Research Facility

ALN Magazine news desk — Wed, 23 Sep 2009 12:00:00 -0500

This STERIS LAR Workshop will take place on October 15, 2009 in Indianapolis, Indiana. Topics include: Cleaning and Sterilization & Decontamination.

Customize Your Sterilizer Online

ALN Magazine news desk — Wed, 23 Sep 2009 12:00:00 -0500

Tuttnauer has recently launched “Build Your Tuttnauer Autoclave.” This application allows you to customize your very own autoclave, step by step.

Xybion Expands Software to Include Full Range of Vivarium Management Capabilities

ALN Magazine news desk — Wed, 23 Sep 2009 12:00:00 -0500

Xybion Medical Systems, developer of Pristima™, announced the expansion of its portfolio of software tools to manage critical medical research information through a strategic partnership with Locus Technology, Inc.

Monkey DNA Swap Provides Options for Mitochondrial Disease

ALN Magazine news desk — Wed, 23 Sep 2009 12:00:00 -0500

Scientists report that a new technique for exchanging DNA between egg cells may provide new options for preventing certain inherited disorders that pass from mother to child in mitochondria, the structures that create energy inside nearly all the body’s cells.

Automatic Data Collection Systems for Animal Care Facilities

ALN Magazine news desk — Wed, 16 Sep 2009 12:00:00 -0500

Today’s animal care facilities can increase efficiencies of routine husbandry management tasks by utilizing the numerous automatic data collection technologies available.

Management Tip #38: The Two Most Important Management Secrets

ALN Magazine news desk — Wed, 16 Sep 2009 12:00:00 -0500

Your expectations of people and their expectations of themselves are the key factors in how well people perform at work. Part 2: The Galatea Effect — The Power of Self-Expectations

Robotics Symposium for Leonardo Automation Club Members Announced

ALN Magazine news desk — Wed, 16 Sep 2009 12:00:00 -0500

The purpose of this symposium, to be held in Milan September 21-23, 2009, is to bring together science and technology with an overview on the evolution of robotics, its benefit on repetitive operations and possible applications in laboratory animal facilities.

Study: H1N1 Virus May Have Advantage over Seasonal Influenza

ALN Magazine news desk — Wed, 16 Sep 2009 12:00:00 -0500

Preliminary findings in ferrets suggest that the novel 2009 H1N1 influenza virus may out-compete human seasonal influenza viruses, researchers say. National Institutes of Health, 9/1

NIAID Funds Trials Examining Antimicrobial Drug Resistance

ALN Magazine news desk — Wed, 16 Sep 2009 12:00:00 -0500

Scientists are addressing the threat of antimicrobial drug resistance by launching two new clinical trials aimed at prolonging the effectiveness of currently available antibacterial drugs. The concept underlying both studies: Less is more.

Researchers Find Lung Cancer Oncogene Holds Key to Turning Off Cancer

ALN Magazine news desk — Wed, 16 Sep 2009 12:00:00 -0500

Scientists at the Mayo Clinic have found that the lung cancer oncogene PKCiota is necessary for the proliferation of lung cancer stem cells. These stem cells are rare and powerful master cells that manufacture the other cells that make up lung tumors and are resistant to chemotherapy treatment.

Spare Gene Is Fodder for Fishes’ Evolution

ALN Magazine news desk — Wed, 16 Sep 2009 12:00:00 -0500

Scientists have suspected that spare parts in the genome—extra copies of functional genes that arise when genes or whole genomes get duplicated—might sometimes provide the raw materials for the evolution of new traits. Now, researchers report a discovery of a prime example of this in fish.

Neurobehavioral Core Facilities

ALN Magazine news desk — Wed, 09 Sep 2009 12:00:00 -0500

Behavioral core facilities encourage multi-disciplined research, expanding on our previous knowledge of the workings of the brain and any associated disorders, providing equipment and expertise in a central location, in an effort to move neuroscience into the future, and should be considered by more institutions.

Management Tip #36: The Two Most Important Management Secrets

ALN Magazine news desk — Wed, 09 Sep 2009 12:00:00 -0500

Your expectations of people and their expectations of themselves are the key factors in how well people perform at work.

Gene Discovery Identifies a Critical Protein's Role in Hearing

ALN Magazine news desk — Wed, 09 Sep 2009 12:00:00 -0500

In humans, hereditary hearing loss is one of the most common birth defects, yet the majority of genes required for audition is thought to remain unidentified.

Mouse Brain Rewires to Recuperate Neural Function After Stroke

ALN Magazine news desk — Wed, 09 Sep 2009 12:00:00 -0500

A Japanese research group has found that after a cerebral stroke in one side of a mouse brain, the other side of the brain rewires its neural circuits to recuperate from damaged neural function.

Iowa State Researchers Receive ARRA Grants

ALN Magazine news desk — Wed, 09 Sep 2009 12:00:00 -0500

Iowa State University researchers have so far won 19 grants worth a total of $7.7 million from federal agencies awarding money from the American Recovery and Reinvestment Act.

Mouse Studies Reveal How Bacteria Causes Some Colon Cancers

ALN Magazine news desk — Wed, 09 Sep 2009 12:00:00 -0500

Johns Hopkins scientists say they have figured out how bacteria that cause diarrhea may also be the culprit in some colon cancers.

Shanghai Sharing Conference Convenes in September

ALN Magazine news desk — Wed, 26 Aug 2009 12:00:00 -0500

The leadership of the laboratory animal science community will join together to network, share strategies for building and sustaining world-class animal research programs, and learn from one another about managing the complexities of aligning purpose with practice in a global economy at the second Sharing Conference in Shanghai, China.

Management Tip #35: Read any good management books lately?

ALN Magazine news desk — Wed, 26 Aug 2009 12:00:00 -0500

After reading a good book on business or self-improvement, if you simply put it down and say "that was a good read," you may as well have read a novel. Reading a book is one thing. But to incorporate what you've read into your life, you'll need to take it a step further and actually study the material.

Alzheimer's Mice Show Memory Deficits with Oxygen Treatment

ALN Magazine news desk — Wed, 26 Aug 2009 12:00:00 -0500

Studies on mice suggest that people genetically predisposed to Alzheimer's disease or with excessive amounts of beta amyloid in their brains are at increased risk of developing the disease earlier if they receive high concentrations of oxygen, known as hyperoxia.

Studies in Mice Offer Breakthrough in Dengue Fever

ALN Magazine news desk — Wed, 26 Aug 2009 12:00:00 -0500

Dengue viruses are spreading throughout the world affecting more than 100 countries, including the U.S. Recent studies, using mice, have offered information in developing a vaccine and other treatments against the most deadly strains of the disease.

Imitation Offers Insights on Social Bonding

ALN Magazine news desk — Wed, 26 Aug 2009 12:00:00 -0500

A new study reports that monkeys prefer humans who imitate them over those who don’t. Mimicry may be an ancient behavior for primates to form social groups. Observing how imitation promotes bonding in primates may lead to insights in disorders such as certain forms of autism.

New NIH Director Sworn In

ALN Magazine news desk — Wed, 26 Aug 2009 12:00:00 -0500

Francis S. Collins, M.D., Ph.D. became the 16th director of the National Institutes of Health. He was nominated to lead the NIH by President Obama on July 8, and was unanimously confirmed by the U.S. Senate on August 7.

DHS Stands Behind BSL-4 Research in Kansas

ALN Magazine news desk — Wed, 19 Aug 2009 12:00:00 -0500

In a 30 page rebuttal, the Department of Homeland Security defended its selection of Kansas State University as the site for a National Bio and Agro-Defense Facility. Among other pathogens, the NBAF would conduct research on highly infectious foot-and-mouth disease.

Management Tip #34: Screening a Candidate by Phone

ALN Magazine news desk — Wed, 19 Aug 2009 12:00:00 -0500

Susan M. Heathfield of About.com says, "The telephone interview saves managerial time and eliminates unlikely candidates." A list of prepared questions help the process go smoothly.

New European Center for Training in Laboratory Animal Science

ALN Magazine news desk — Wed, 19 Aug 2009 12:00:00 -0500

The recently launched Fondazione Guido Bernardini is as an independent, non-profit, educational center devoted to assist in meeting the need for continuous, post qualification professional training and development in laboratory animal science.

Cancer Tumors Killed by "Nanobees"

ALN Magazine news desk — Wed, 19 Aug 2009 12:00:00 -0500

Studies suggest that using nanobees to "fly" in and target cancerous tumors could lessen the growth and size of established tumors and also act at early stages to prevent cancer from developing.

Tooth Grown from Stem Cells

ALN Magazine news desk — Wed, 19 Aug 2009 12:00:00 -0500

Researchers report using stem cells to grow a replacement tooth for an adult mouse suggesting that using similar techniques in humans could restore function to patients with organ failure.

Strep Throat Antibodies Linked to OCD in Mice

ALN Magazine news desk — Wed, 19 Aug 2009 12:00:00 -0500

Recent studies indicate that pediatric obsessive-compulsive disorder (OCD) may develop from an inappropriate immune response to the bacteria causing common throat infections.

Perspectives in Alkaline Hydrolysis

ALN Magazine news desk — Wed, 12 Aug 2009 12:00:00 -0500

The commercialization of alkaline hydrolysis technology used in tissue digester systems has led to many new innovations in the process and equipment design — some of which have led consumers to many perceptions and misconceptions regarding the process due to the changing technology.

Management Tip #33: Mistakes New Managers Make: The Four Biggies

ALN Magazine news desk — Wed, 12 Aug 2009 12:00:00 -0500

By avoiding these four common mistakes, you’ll be well on your way towards becoming an excellent manager. This week — Mistake #4: Failing to Seek Help

Scientists Re-Form Nerve Connections

ALN Magazine news desk — Wed, 12 Aug 2009 12:00:00 -0500

Researchers at the UCSD School of Medicine, in experiments with rats, found that regenerating axons can be guided to their correct targets where they can re-form connections after spinal cord injury.

The Way You Eat and Breast Cancer

ALN Magazine news desk — Wed, 12 Aug 2009 12:00:00 -0500

A recent study with mice suggests the method by which calories are restricted may be more important for cancer protection than the actual overall degree of calorie restriction.

Immune Cells Cause More Post-Stroke Brain Damage

ALN Magazine news desk — Wed, 12 Aug 2009 12:00:00 -0500

Japanese researchers showed that mice that were deficient in the immune cells —that floods the brain soon after a stroke, causing inflammation and more neurological damage— suffered far less brain damage after a stroke compared to normal mice.

Neurons Generated in the Adult Intestine

ALN Magazine news desk — Wed, 12 Aug 2009 12:00:00 -0500

In a study, carried out on adult mice, drugs similar to the neurotransmitter serotonin increase the production of new neurons in the gut, confirming that an adult intestine can generate neurons in the enteric nervous system in the gut's wall that controls the gastrointestinal system.

Stem Cell Research May Reduce Animal Experiments

ALN Magazine news desk — Wed, 12 Aug 2009 12:00:00 -0500

Researchers from the University of Bath, U.K. are embarking on a project to use stem cell technology that could reduce the number of animal experiments used to study conditions such as motor neuron disease.

Imaging Looks to the Future

ALN Magazine news desk — Wed, 5 Aug 2009 12:00:00 -0500

Emerging trends, techniques, and processes for the imaging field include optical and digital imaging. In laboratory animal science, the tools and technologies used for imaging are constantly changing. Researchers are no longer forced to work around bulky imaging machines—and the technology has become more user-friendly.

Management Tip #32: Mistakes New Managers Make: The Four Biggies

ALN Magazine news desk — Wed, 5 Aug 2009 12:00:00 -0500

By avoiding these four common mistakes, you’ll be well on your way towards becoming an excellent manager. This week — Mistake #3: Becoming Too Authoritarian

Blue Dye No. 1 Treats Spine Injury in Rats

ALN Magazine news desk — Wed, 5 Aug 2009 12:00:00 -0500

Researchers discovered that the commonly used food additive FD&C blue dye No. 1 is remarkably similar to a lab compound that blocks a key step in nerve inflammation.

Allergy Drug Reduces Obesity and Diabetes in Mice

ALN Magazine news desk — Wed, 5 Aug 2009 12:00:00 -0500

Using two common over-the-counter allergy medications researchers reduced both obesity and Type 2 diabetes in mice.

Scientists Caution Swine Flu May Effect Unborn

ALN Magazine news desk — Wed, 5 Aug 2009 12:00:00 -0500

Scientists discovered that the H1N1 flu virus changes the workings of genes that control fetal brain growth and development in mice.

Reducing Specific Protein Levels May Delay Aging

ALN Magazine news desk — Wed, 5 Aug 2009 12:00:00 -0500

A team of scientists have discovered that by reducing the levels of the protein p38MAPK, they were able to delay the aging of multiple tissues, in genetically modified mice.

Green and Lean: Methods of Improving Lab Animal Room Ventilation

ALN Magazine news desk — Wed, 29 Jul 2009 12:00:00 -0500

Hardly a day goes by where we don’t hear about the rising cost of energy, its scarcity, and the negative impacts of fossil fuels on the global environment.

Management Tip #31: Mistakes New Managers Make: The Four Biggies

ALN Magazine news desk — Wed, 29 Jul 2009 12:00:00 -0500

By avoiding these four common mistakes, you’ll be well on your way towards becoming an excellent manager. This week — Mistake #2: Doing It All

$3 Million in Stimulus Money Allocated for Post-Doctoral Research

ALN Magazine news desk — Wed, 29 Jul 2009 12:00:00 -0500

An $3 million award from the American Recovery and Reinvestment Act (ARRA, the "stimulus package") has been granted to Vanderbilt University’s Institute for Global Health to fund jobs for early-career scientists. The grant will allow 13 research fellows and 10 advanced research fellows to join the National Institutes of Health’s Clinical Research Training Scholars and Fellows Program.

Embryonic-Like Cells Repair Damaged Mouse Hearts

ALN Magazine news desk — Wed, 29 Jul 2009 12:00:00 -0500

When ordinary cells, reprogrammed to act like embryonic stem cells, were injected into mice whose hearts had been damaged by a heart attack, they helped improve both the structure and function of the heart.

Stem Cells offer Hope for Dementia Patients

ALN Magazine news desk — Wed, 29 Jul 2009 12:00:00 -0500

Scientists have successfully used injections of stem cells to repair damaged parts of the brain and restore lost memory in mice.

NIAID to Launch Clinical Trials for Influenza Vaccine

ALN Magazine news desk — Wed, 29 Jul 2009 12:00:00 -0500

Scientists in a network of medical research institutions across the U.S. are set to begin a series of clinical trials to gather critical data about influenza vaccines, including two candidate H1N1 flu vaccines.

What's NIH Doing with Its Stimulus Money?

ALN Magazine news desk — Wed, 22 Jul 2009 12:00:00 -0500

Earlier this year, the NIH received $10.4 billion from the American Recovery and Reinvestment Act with $8.2 billion to go towards grants to fund scientific research. And the applications keep rolling in.

Management Tip #30: Mistakes New Managers Make: The Four Biggies

ALN Magazine news desk — Wed, 22 Jul 2009 12:00:00 -0500

By avoiding these four common mistakes, you’ll be well on your way towards becoming an excellent manager. This week — Mistake #1: Becoming Buddies with Employees

Swine Flu Goes Deeper Into the Body than Regular Flu—Even Into Intestines

ALN Magazine news desk — Wed, 22 Jul 2009 12:00:00 -0500

Researchers have revealed that seasonal flu and swine flu cause different symptoms because they have different destinations.

Low-calorie Diet Slows Aging in Monkeys

ALN Magazine news desk — Wed, 22 Jul 2009 12:00:00 -0500

A 20-year study of monkeys shows that a reduced-calorie diet pays off in less disease and longer life, a finding that could apply to humans.

Scientists Create "Artificial Brain Cell"

ALN Magazine news desk — Wed, 22 Jul 2009 12:00:00 -0500

Using the artificial brain cells, called a "delivery electrode," scientists have managed to pass messages used by the brain to control many actions in the body.

While Public Praises Scientists, Scientists Fault Public, Media

ALN Magazine news desk — Wed, 22 Jul 2009 12:00:00 -0500

A new report finds that overwhelming majorities of Americans believe that science has had a positive effect on society and that science has made life easier for most people.

USDA Settlement Means More Data Online

ALN Magazine news desk — Wed, 15 Jul 2009 12:00:00 -0500

Animal research facilities will have more information online about their experiments under a court settlement signed July 1st by the HSUS and USDA.

Management Tip #29: Cure Employee Negativity

ALN Magazine news desk — Wed, 15 Jul 2009 12:00:00 -0500

How you address negativity depends on whether you control it and how it started in the first place. The timeliness of your intervention also has an impact.

Genetically Engineered Mice Yield Clues to 'Knocking Out' Cancer

ALN Magazine news desk — Wed, 15 Jul 2009 12:00:00 -0500

Researchers have demonstrated that deleting two genes in mice leads to several types of tumors, providing additional evidence that such stress contributes to the development of cancer.

Memory Decline Reversed in Mouse Model

ALN Magazine news desk — Wed, 15 Jul 2009 12:00:00 -0500

US scientists say a human growth factor used to stimulate blood stem cells to proliferate in bone marrow can also reverse memory impairment in mice.

MIT Researchers Find New Actions of Neurochemicals

ALN Magazine news desk — Wed, 15 Jul 2009 12:00:00 -0500

Although the tiny roundworm Caenorhabditis elegans has only 302 neurons in its entire nervous system, studies of this animal have significantly advanced our understanding of human brain function.

Universitat Autònoma de Barcelona Researchers First to Clone Mice in Spain

ALN Magazine news desk — Wed, 8 Jul 2009 12:00:00 -0500

Cloe, Cleo and Clona are three female brown-colored mice and were born respectively on May 12, June 3, and June 10. By means of nuclear transfer techniques, scientist collected mature oocytes, removed their chromosomes and substituted them for the nucleus of an adult somatic cell.

Management Tip #28: Bored Employees Are More Disgruntled Than Overworked Onesn

ALN Magazine news desk — Wed, 8 Jul 2009 12:00:00 -0500

Businesses may realize far more negative consequences from bored employees than from those who report having “too much work”. Employees who are bored have lower job satisfaction, sense of accomplishment, and pride in their employers compared to all other workers.

Mice with Chromosomal Duplication Mirror Symptoms of Autism

ALN Magazine news desk — Wed, 8 Jul 2009 12:00:00 -0500

A particular chromosomal duplication in mice, when inherited patrilineally, causes them to behave in ways that parallel behavior associated with autism in humans.

Pig Connective Tissues Transformed into Stem Cells

ALN Magazine news desk — Wed, 8 Jul 2009 12:00:00 -0500

Researchers at the University of Missouri have developed a method for creating stem cells from fetal-pig fibroblasts, with the hope of creating an animal model stem-cell culture for therapy research.

Research: CNS Serotonin Vital to Mouse Behavior

ALN Magazine news desk — Wed, 8 Jul 2009 12:00:00 -0500

German researchers at the Max Delbrück Center for Molecular Medicine have discovered that the signaling molecule serotonin plays a significant role in normal mouse status, behavior, and parenting.

Underground Vivarium Plan Approved at University of Iowa

ALN Magazine news desk — Wed, 8 Jul 2009 12:00:00 -0500

The Iowa state Board of Regents has approved a plan for building a 35,200 square foot vivarium underground at the University of Iowa.

Green and Lean: Methods of Improving Lab Animal Room Ventilation