ASBMB AudioPhiles

JBC Podcast: Vitamin C’s potential role in epigenetics

Wed, 08 May 2013 15:58:33 EST

May 10 2013 — In this podcast we hear an interview with Gaofeng Wang at the University of Miami Wang talks about his Paper of the Week Ascorbate Induces Ten-Eleven Translocation Methylcytosine Dioxygenase-mediated Generation of 5-Hydroxymethylcytosine The paper delves into how vitamin C may play a role in epigenetics.

JLR Podcast: Fsp27 and fasting

Wed, 17 Apr 2013 15:07:51 EST

April 17 2014 — In this podcast we hear an interview with Pedro Marrero from the University of Barcelona about his group’s article in the Journal of Lipid Research Fsp2

JBC Podcast: gedunin, Hsp90 and p23

Thu, 07 Mar 2013 10:48:33 EST

In this podcast we hear an interview with Ahmed Chadli at the Georgia Regents University who talks about his Paper of the Week “Gedunin Inactivates the Co-chaperone p23 Protein Causing Cancer Cell Death by Apoptosis” The paper delves into the molecular mechanism of action of a naturally occurring product that is found in the neem tree an Indian medicinal plant.

JBC Podcast: sirtuins and JBC's Best of 2012

Wed, 13 Feb 2013 18:42:16 EST

In this podcast we hear an interview between JBC Associate Editor Joel Gottesfeld and John Denu from the University of Wisconsin-Madison about JBC’s Best of 2012 The Journal’s associate editors chose from among more than 4,000 articles published throughout the year selecting 22 one for each of the Journal’s affinity categories An affinity category corresponds to a section of the Journal’s table of contents. Denu co-authored two of the best of 2012 In the field of metabolism he coauthored the paper “Regulation of Glycolytic Enzyme Phyosphoglycerate Mutase-1 by Sirt1 Protein-mediated Deacetylation,” which was published in February In the field of enzymology he coauthored the paper Sirt3 “Protein Deacetylates Isocitrate Dehydrogenase 2 and Regulates Mitochondrial Redox Status,” which was published in April.

JBC Podcast: MDEG hyperactivation and caspase-8 activation

Fri, 01 Feb 2013 11:34:39 EST

Feb 1 2013 — Today we hear an interview with Wei-Xing Zong from Stony Brook University who talks about his group’s JBC Paper of the Week Hyperactivation of the mammalian degenerin MDEG promotes caspase-8 activation and apoptosis The paper and interview investigate how misregulation of the degenerin family of ion channels leads to cell death.

JBC Podcast: Parkin deficiency and myocardial infarction

Fri, 11 Jan 2013 10:53:36 EST

Jan 11 2013 — In this podcast we hear an interview with Åsa Gustafsson from the University of California San Diego who talks about her JBC Paper of the Week Parkin Protein Deficiency Exacerbates Cardiac Injury and Reduces Survival following Myocardial Infarction The paper delves into the cardiac defects brought on by a protein involved in Parkinson’s disease.

JBC Podcast: the molecular biology of Friedreich ataxia

Fri, 14 Dec 2012 13:16:39 EST

Dec 14 2012 -- In this podcast we hear an interview with Elena Hidalgo from the Unviersity of Pompeu Fabra in Barcelona Spain who talks about her JBC Paper of the Week Cells Lacking Pfh1 a Fission Yeast Homolog of Mammalian Frataxin Protein Display Constitutive Activation of the Iron Starvation Response The paper delves into the molecular biology of Friedreich ataxia a rare neurological disease.