AudiommunityA podcast about our bodies' never-ending fight with the outside worldhttps://audiommunity.substack.com/podcastSubstackSat, 11 Apr 2026 05:53:05 GMThttps://api.substack.com/feed/podcast/7655419.rssAudiommunity OrgA podcast about our bodies' never-ending fight with the outside worldepisodicAudiommunity Orgcontact@audiommunity.orgno<![CDATA[Episode 54 - Poop is lumen]]>In this episode, Matt and Kevin discuss a new paper showing a new technique to add poly-A tails to every RNA in a tissue section, enabling capture by spot-based sequencing technologies. This let’s them see microbes and host-encoded non-messenger RNAs, giving a much better view into intestinal biology.

Plus, Matt thinks it’s funny they’re taking tissue slices though fecal pellets and Kevin routinely says “microvillus” when he means “villus”, and pretends to know the anatomy of the intestines when he clearly doesn’t, despite being an Assistant Professor in the GI division at a hospital.

Links

* The paper - Spatial transcriptomics maps host–gut microbiome biogeography at high resolution

* The technologies - 10x Visium, StereoSeq, and CosMx

* Wikipedia - human digestive system



Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/episode-54-poop-is-lumensubstack:post:193460396Tue, 07 Apr 2026 13:39:46 GMTAudiommunity OrgNo4340254fullIn this episode, Matt and Kevin discuss a new paper showing a new technique to add poly-A tails to every RNA in a tissue section, enabling capture by spot-based sequencing technologies. This let’s them see microbes and host-encoded non-messenger RNAs, giving a much better view into intestinal biology. Plus, Matt thinks it’s funny they’re taking tissue slices though fecal pellets and Kevin routinely says “microvillus” when he means “villus”, and pretends to know the anatomy of the intestines when he clearly doesn’t, despite being an Assistant Professor in the GI division at a hospital. Links * The paper - Spatial transcriptomics maps host–gut microbiome biogeography at high resolution * The technologies - 10x Visium, StereoSeq, and CosMx * Wikipedia - human digestive system Get full access to Audiommunity Org at audiommunity.substack.com/subscribeIn this episode, Matt and Kevin discuss a new paper showing a new technique to add poly-A tails to every RNA in a tissue section, enabling capture by spot-based sequencing technologies. This let’s them see microbes and host-encoded non-messenger RNAs, giving a much better view into intestinal biology. Plus, Matt thinks it’s funny they’re taking tissue slices though fecal pellets and Kevin routinely says “microvillus” when he means “villus”, and pretends to know the anatomy of the intestines when he clearly doesn’t, despite being an Assistant Professor in the GI division at a hospital. Links * The paper - Spatial transcriptomics maps host–gut microbiome biogeography at high resolution * The technologies - 10x Visium, StereoSeq, and CosMx * Wikipedia - human digestive system Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 53 - Something catastrophic]]>In this episode, Matt and Kevin discuss a new paper from Matt’s old boss that shows that repeated “vaccination” against a completely harmless protein from chicken egg whites stimulates broad-based protection against a host of viral and bacterial pathogens, not to mention prevents mice from developing allergies.

So should everyone rush to drip LPS and ovalbumin into their noses? Mmmm… not so fast.

Plus, we kvetch about new NIH policies for the politburo-tization of grant review. A new era of American Lysenkoism is here!

Links

* The paper: Mucosal vaccination in mice provides protection from diverse respiratory threats

* The new NIH policy on grant review - doesn’t sound so bad, but you need to read it in context.



Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/episode-53-something-catastrophicsubstack:post:190036824Fri, 06 Mar 2026 13:31:23 GMTAudiommunity Org, Kevin Bonham, and MattNo4234In this episode, Matt and Kevin discuss a new paper from Matt’s old boss that shows that repeated “vaccination” against a completely harmless protein from chicken egg whites stimulates broad-based protection against a host of viral and bacterial pathogens, not to mention prevents mice from developing allergies. So should everyone rush to drip LPS and ovalbumin into their noses? Mmmm… not so fast. Plus, we kvetch about new NIH policies for the politburo-tization of grant review. A new era of American Lysenkoism is here! Links * The paper: Mucosal vaccination in mice provides protection from diverse respiratory threats * The new NIH policy on grant review - doesn’t sound so bad, but you need to read it in context. Get full access to Audiommunity Org at audiommunity.substack.com/subscribeIn this episode, Matt and Kevin discuss a new paper from Matt’s old boss that shows that repeated “vaccination” against a completely harmless protein from chicken egg whites stimulates broad-based protection against a host of viral and bacterial pathogens, not to mention prevents mice from developing allergies. So should everyone rush to drip LPS and ovalbumin into their noses? Mmmm… not so fast. Plus, we kvetch about new NIH policies for the politburo-tization of grant review. A new era of American Lysenkoism is here! Links * The paper: Mucosal vaccination in mice provides protection from diverse respiratory threats * The new NIH policy on grant review - doesn’t sound so bad, but you need to read it in context. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 52 - Close to the squeezey part ]]>Oh hey, look, we’re on substack now!

In this paper, Matt and Kevin discuss a new paper identifying and describing a new kind of macrophage (or is it a dendritic cell?) they call “adenophages”. The cells live in salivary and other exocrine glands, and are really good at phagocytosis and antigen presentation. But they also help squeeze out spit?

Links

* The Paper: Adenophages are an atypical macrophage population in exocrine glands sustained by ILC2-derived GM-CSF

* Wikipedia article on salivary glands



Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/episode-52-close-to-the-squeezeysubstack:post:186348850Mon, 02 Feb 2026 15:11:12 GMTKevin Bonham and MattNo5284522Oh hey, look, we’re on substack now! In this paper, Matt and Kevin discuss a new paper identifying and describing a new kind of macrophage (or is it a dendritic cell?) they call “adenophages”. The cells live in salivary and other exocrine glands, and are really good at phagocytosis and antigen presentation. But they also help squeeze out spit? Links * The Paper: Adenophages are an atypical macrophage population in exocrine glands sustained by ILC2-derived GM-CSF * Wikipedia article on salivary glands Get full access to Audiommunity Org at audiommunity.substack.com/subscribeOh hey, look, we’re on substack now! In this paper, Matt and Kevin discuss a new paper identifying and describing a new kind of macrophage (or is it a dendritic cell?) they call “adenophages”. The cells live in salivary and other exocrine glands, and are really good at phagocytosis and antigen presentation. But they also help squeeze out spit? Links * The Paper: Adenophages are an atypical macrophage population in exocrine glands sustained by ILC2-derived GM-CSF * Wikipedia article on salivary glands Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 51 - F is for Flume]]>science communication, and government funding.

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/f-is-for-flume-15fepisodes/episode051/index.htmlMon, 22 Dec 2025 00:00:00 GMTAudiommunity OrgA retrospective on audiommunity, and some solid rants about the importance of science, science communication, and government funding.No3174251A retrospective on audiommunity, and some solid rants about the importance of science, science communication, and government funding. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 50 – Kevin has learned a tautology]]>this time looking at the immunological implications of
a variant of a gene called Apolipoprotein E
that has been linked to Alzheimer's and other neurodegenerative diseases.
It's a long one, and we get snarky in this one folks!
Buckle up!

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/kevin-has-learned-a-tautology-a7depisodes/episode050/index.htmlWed, 10 Dec 2025 00:00:00 GMTAudiommunity OrgIn this episode, Matt and Kevin stick with the brain, this time looking at the immunological implications of a variant of a gene called Apolipoprotein E that has been linked to Alzheimer's and other neurodegenerative diseases. It's a long one, and we get snarky in this one folks! Buckle up!No7496250fullIn this episode, Matt and Kevin stick with the brain, this time looking at the immunological implications of a variant of a gene called Apolipoprotein E that has been linked to Alzheimer's and other neurodegenerative diseases. It's a long one, and we get snarky in this one folks! Buckle up! Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 49 - Scatch that itchy worm in your head]]>https://nicoleackermans.com)
to discuss her recent review paper tracing human thoughts about headbutting
from 10,000 BCE to the present day.
How are animals like bighorn sheep and woodpeckers protected
from brain injury?
Actually, wait... **are** they protected from brain injury?

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/scatch-that-itchy-worm-in-your-head-38cepisodes/episode049/index.htmlWed, 19 Nov 2025 00:00:00 GMTAudiommunity OrgIn this episode, Matt and Kevin are joined by [Nicole Ackermans](https://nicoleackermans.com) to discuss her recent review paper tracing human thoughts about headbutting from 10,000 BCE to the present day. How are animals like bighorn sheep and woodpeckers protected from brain injury? Actually, wait... **are** they protected from brain injury?No4231249In this episode, Matt and Kevin are joined by [Nicole Ackermans](https://nicoleackermans.com) to discuss her recent review paper tracing human thoughts about headbutting from 10,000 BCE to the present day. How are animals like bighorn sheep and woodpeckers protected from brain injury? Actually, wait... **are** they protected from brain injury? Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 48 – The Tyranny of the FACS machine]]>from the University of Toledo -
we're talking neonatal Tregs!

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/the-tyranny-of-the-facs-machine-2f6episodes/episode048/index.htmlThu, 06 Nov 2025 00:00:00 GMTAudiommunity OrgIn this episode Matt and Kevin welcome special guest Zach Hilt from the University of Toledo - we're talking neonatal Tregs!No4647248fullIn this episode Matt and Kevin welcome special guest Zach Hilt from the University of Toledo - we're talking neonatal Tregs! Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 47 - When you're a hammer]]>but Matt insists that it's really about Lupus

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/when-youre-a-hammer-982episodes/episode047/index.htmlThu, 23 Oct 2025 00:00:00 GMTAudiommunity OrgIn this episode, Matt and Kevin talk about glycoRNAs and inflammation, but Matt insists that it's really about LupusNo3598247In this episode, Matt and Kevin talk about glycoRNAs and inflammation, but Matt insists that it's really about Lupus Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 46 – Walk farther and farther to the left]]>from the lab of David Baltimore (RIP)
in which the gene encoding RAG-1,
one of two genes that is responsible for
the VDJ recombination -
a mechanism for the generation of diversity
in the adaptive immune system.

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/walk-farther-and-farther-to-the-left-060episodes/episode046/index.htmlFri, 19 Sep 2025 00:00:00 GMTAudiommunity OrgMatt and Kevin take a humbling look back a classic 1989 immunology paper from the lab of David Baltimore (RIP) in which the gene encoding RAG-1, one of two genes that is responsible for the VDJ recombination - a mechanism for the generation of diversity in the adaptive immune system.No3520246fullMatt and Kevin take a humbling look back a classic 1989 immunology paper from the lab of David Baltimore (RIP) in which the gene encoding RAG-1, one of two genes that is responsible for the VDJ recombination - a mechanism for the generation of diversity in the adaptive immune system. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 45 - Big if true]]>is this a paradigm shift in how we do science,
or a transpararent and cynical effort to slurp up all of the citations for being first?
Por que no los dos?

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/big-if-true-0dbepisodes/episode045/index.htmlWed, 27 Aug 2025 00:00:00 GMTAudiommunity OrgSomeone made an AI-based "virtual lab" to engineer nanobodies - is this a paradigm shift in how we do science, or a transpararent and cynical effort to slurp up all of the citations for being first? Por que no los dos?No4692245Someone made an AI-based "virtual lab" to engineer nanobodies - is this a paradigm shift in how we do science, or a transpararent and cynical effort to slurp up all of the citations for being first? Por que no los dos? Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 44 – Evolution - it's a hell of a drug]]>Well... sort of

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/evolution-its-a-hell-of-a-drug-338episodes/episode044/index.htmlMon, 11 Aug 2025 00:00:00 GMTAudiommunity OrgBacteria have immune systems? Even adaptive immune systems? And autoimmunity? Well... sort ofNo3874244fullBacteria have immune systems? Even adaptive immune systems? And autoimmunity? Well... sort of Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 43 - Why don't you go stain a brain?]]>which (once again) undermines the idea of immune privilage,
and also points to an interesting evolutionary question:
why would T-cells migrating from fat to the brain affect hunger response?

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/why-dont-you-go-stain-a-brain-d4aepisodes/episode043/index.htmlMon, 21 Jul 2025 00:00:00 GMTAudiommunity OrgMatt and Kevin discuss a new paper about the "subfornical organ" which (once again) undermines the idea of immune privilage, and also points to an interesting evolutionary question: why would T-cells migrating from fat to the brain affect hunger response?No4584243Matt and Kevin discuss a new paper about the "subfornical organ" which (once again) undermines the idea of immune privilage, and also points to an interesting evolutionary question: why would T-cells migrating from fat to the brain affect hunger response? Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 42 – Hypercube in the common parlance]]>Kate, Kevin, and Matt discuss a paper modeling just how wrong you are -
that is, unless you don't mind children dying.

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/hypercube-in-the-common-parlance-88depisodes/episode042/index.htmlTue, 03 Jun 2025 00:00:00 GMTAudiommunity OrgThink vaccines aren't important? Kate, Kevin, and Matt discuss a paper modeling just how wrong you are - that is, unless you don't mind children dying.No4115242fullThink vaccines aren't important? Kate, Kevin, and Matt discuss a paper modeling just how wrong you are - that is, unless you don't mind children dying. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 41 - Sense of adventure]]>an assistant professor at Emory's Hope Clinic,
about the current state of American biomedical science.

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/sense-of-adventure-732episodes/episode041/index.htmlMon, 26 May 2025 00:00:00 GMTAudiommunity OrgMatt and Kevin speak with Abbie Smith, an assistant professor at Emory's Hope Clinic, about the current state of American biomedical science.No4004Matt and Kevin speak with Abbie Smith, an assistant professor at Emory's Hope Clinic, about the current state of American biomedical science. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 40 – Mohawk Mice, Precious]]>Matt and Kevin discuss an excellent paper showing how skin-regulatory Tregs have a distinct role in protecting hair follicles from autoreactive CD8 T-cells; it’s a really clear illustration of why animal research is critical to advancing our understanding.

Also, for future reference, apparently riverside.fm’s bot transcription cannot distinguish Tregs from T-rex.

Links

* The paper

* Yes she will, Precious, she will get the hose



Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/mohawk-mice-precious-c19episodes/episode040/index.htmlWed, 21 May 2025 00:00:00 GMTAudiommunity OrgNo3763240fullMatt and Kevin discuss an excellent paper showing how skin-regulatory Tregs have a distinct role in protecting hair follicles from autoreactive CD8 T-cells; it’s a really clear illustration of why animal research is critical to advancing our understanding. Also, for future reference, apparently riverside.fm’s bot transcription cannot distinguish Tregs from T-rex. Links * The paper * Yes she will, Precious, she will get the hose Get full access to Audiommunity Org at audiommunity.substack.com/subscribeMatt and Kevin discuss an excellent paper showing how skin-regulatory Tregs have a distinct role in protecting hair follicles from autoreactive CD8 T-cells; it’s a really clear illustration of why animal research is critical to advancing our understanding. Also, for future reference, apparently riverside.fm’s bot transcription cannot distinguish Tregs from T-rex. Links * The paper * Yes she will, Precious, she will get the hose Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 39 - Ban the Lomb-Scargle]]>is two guys mansplaining menstruation...but also cool immunology!

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/ban-the-lomb-scargle-249episodes/episode039/index.htmlTue, 06 May 2025 00:00:00 GMTAudiommunity OrgI'm certain that what you've really been missing in these dark times is two guys mansplaining menstruation...but also cool immunology!No3816239I'm certain that what you've really been missing in these dark times is two guys mansplaining menstruation...but also cool immunology! Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 38 – It is a problem to encounter LPS in your eye]]>seems to intentionally shuttle certain microbes from the gut to lymph nodes and the spleen.

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/it-is-a-problem-to-encounter-lps-ceeepisodes/episode038/index.htmlTue, 15 Apr 2025 00:00:00 GMTAudiommunity OrgIn this episode, we're talking about a strange phenomenon where the immune system seems to intentionally shuttle certain microbes from the gut to lymph nodes and the spleen.No4608238fullIn this episode, we're talking about a strange phenomenon where the immune system seems to intentionally shuttle certain microbes from the gut to lymph nodes and the spleen. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 37 - Oh no, it rhymes!]]>and the passage of its product, 2,5-oligoadenylate, through gap junctions.

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/oh-no-it-rhymes-73aepisodes/episode037/index.htmlThu, 27 Mar 2025 00:00:00 GMTAudiommunity OrgIn this episode, we're talking about the OAS-RNaseL virus-sensing pathway, and the passage of its product, 2,5-oligoadenylate, through gap junctions.No4910237In this episode, we're talking about the OAS-RNaseL virus-sensing pathway, and the passage of its product, 2,5-oligoadenylate, through gap junctions. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 36 – Mice touching grass]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/mice-touching-grass-8beepisodes/episode036/index.htmlTue, 18 Mar 2025 00:00:00 GMTAudiommunity OrgHow does "rewilding" mice change their immune system? Also, an interview with an organizer of the Atlanta Stand Up for Science march!No7626236fullHow does "rewilding" mice change their immune system? Also, an interview with an organizer of the Atlanta Stand Up for Science march! Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 35 - One hundred times mosquito, by mass]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/one-hundred-times-mosquito-by-mass-129episodes/episode035/index.htmlFri, 28 Feb 2025 00:00:00 GMTAudiommunity OrgIn this episode, we're talking itch, and the sweet sweet relief you get when degranulating your mast cells.No4666235In this episode, we're talking itch, and the sweet sweet relief you get when degranulating your mast cells. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 34 – A blacksmith that decides to make wheels]]>No, we're not talking (only) about US politics,
we're talking about Postdocs!
And about a new paper showing how academic success
is linked to publications.

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/a-blacksmith-that-decides-to-make-beeepisodes/episode034/index.htmlMon, 10 Feb 2025 00:00:00 GMTAudiommunity OrgAre you bleak, disenchanted, stressed out, and unhappy? No, we're not talking (only) about US politics, we're talking about Postdocs! And about a new paper showing how academic success is linked to publications.No4980234fullAre you bleak, disenchanted, stressed out, and unhappy? No, we're not talking (only) about US politics, we're talking about Postdocs! And about a new paper showing how academic success is linked to publications. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 33 - Emmunity is dead. Long live Audiommunity!]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/emmunity-is-dead-long-live-audiommunity-64eepisodes/episode033/index.htmlThu, 30 Jan 2025 00:00:00 GMTAudiommunity OrgAudiommunity is back! Again!No3663233Audiommunity is back! Again! Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 29 - Camilla's Science is Cursed]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/camillas-science-is-cursed-001episodes/episode029/index.htmlMon, 20 Aug 2018 00:00:00 GMTAudiommunity OrgI swear, we know how to count; this episode was originally recorded back in January, but Camilla's audio file was weirdly corrupted. And in this attempt, Chadene's computer exploded, but we soldiered on without her.No3986129I swear, we know how to count; this episode was originally recorded back in January, but Camilla's audio file was weirdly corrupted. And in this attempt, Chadene's computer exploded, but we soldiered on without her. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 32 – Not an accurate representation of grad school]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/not-an-accurate-representation-of-dacepisodes/episode032/index.htmlMon, 28 May 2018 00:00:00 GMTAudiommunity OrgIn this episode, Chadene, Kate and Kevin discuss Kate's recently published paper about how STING, once thought to be involved only in defense against DNA viruses, actually slows RNA virus replication as well. Also, Chadene throws herself under the bus, and Kevin manages to only talk for about 20% of the time.No4939132fullIn this episode, Chadene, Kate and Kevin discuss Kate's recently published paper about how STING, once thought to be involved only in defense against DNA viruses, actually slows RNA virus replication as well. Also, Chadene throws herself under the bus, and Kevin manages to only talk for about 20% of the time. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 31 - Two Bucket Disease]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/two-bucket-disease-458episodes/episode031/index.htmlSat, 07 Apr 2018 00:00:00 GMTAudiommunity OrgIn this episode, we're talking about *Salmonella*, and the peculiar way in which it tries to keep you eating to keep you alive. Who knew pathogens could be so kind?No4081131In this episode, we're talking about *Salmonella*, and the peculiar way in which it tries to keep you eating to keep you alive. Who knew pathogens could be so kind? Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 30 – No Drop Shadows on Error Bars]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/no-drop-shadows-on-error-bars-f6fepisodes/episode030/index.htmlMon, 26 Feb 2018 00:00:00 GMTAudiommunity OrgIn this episode, Kevin and Camilla discuss *Salmonella* virulence,* and how different strains alter the immunogenicity of pathogens. Oh, and Kate's here too... KATE'S BACK!! WOO!! Dr. Franz has a new job, but is just as snarky and ill-prepared as ever. Plus she refuses to drink on the job.No4352130fullIn this episode, Kevin and Camilla discuss *Salmonella* virulence,* and how different strains alter the immunogenicity of pathogens. Oh, and Kate's here too... KATE'S BACK!! WOO!! Dr. Franz has a new job, but is just as snarky and ill-prepared as ever. Plus she refuses to drink on the job. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 28 – Giant Bag of Autoimmunity]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/giant-bag-of-autoimmunity-50cepisodes/episode028/index.htmlMon, 22 Jan 2018 00:00:00 GMTAudiommunity OrgToday (well, three weeks ago), Matt and Kevin talked about epitope spreading in Lupus, and a ton of crazy mouse models that allowed researchers to dissect the way a single auto-reactive B-cell clone can spread the disease party to its neighbors.No3405128fullToday (well, three weeks ago), Matt and Kevin talked about epitope spreading in Lupus, and a ton of crazy mouse models that allowed researchers to dissect the way a single auto-reactive B-cell clone can spread the disease party to its neighbors. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 27 - Macaque Prison Gangs]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/macaque-prison-gangs-64bepisodes/episode027/index.htmlSat, 23 Dec 2017 00:00:00 GMTAudiommunity OrgIn this episode, we're talking cure for the common cold... or at least, a vaccine for it. Also, Kevin and Matt read the wrong paper, Chadene corrects Kevin's pronunciation of her name (again!) and we give a big round of applause for Dr. Kate Franz (though she's still too busy for us).No3813127In this episode, we're talking cure for the common cold... or at least, a vaccine for it. Also, Kevin and Matt read the wrong paper, Chadene corrects Kevin's pronunciation of her name (again!) and we give a big round of applause for Dr. Kate Franz (though she's still too busy for us). Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 26 – Lies and Magic]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/lies-and-magic-04eepisodes/episode026/index.htmlTue, 05 Dec 2017 00:00:00 GMTAudiommunity OrgIn this episode, we're talking cancer, checkpoint blockade and poop - what's not to love? Also, Camilla is the only one drinking, Matt thinks the study needs more mice, and it took Kevin an extra 2 hours to edit this episode to remove all (he hopes) of his sniffles.No4623126fullIn this episode, we're talking cancer, checkpoint blockade and poop - what's not to love? Also, Camilla is the only one drinking, Matt thinks the study needs more mice, and it took Kevin an extra 2 hours to edit this episode to remove all (he hopes) of his sniffles. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 25 - You're famous if you have a wikipedia page]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/youre-famous-if-you-have-a-wikipedia-6bbepisodes/episode025/index.htmlSun, 19 Nov 2017 00:00:00 GMTAudiommunity OrgWe've got a couple of new hosts - Please give a warm welcome to Chadene Tremaglio and Camilla Engblom! Kate is still holed up in a cave (lab) trying to wrap up her PhD. But she'll soon return... we hope...No3226125We've got a couple of new hosts - Please give a warm welcome to Chadene Tremaglio and Camilla Engblom! Kate is still holed up in a cave (lab) trying to wrap up her PhD. But she'll soon return... we hope... Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 24 – The Devil Went Down to... awww, C'mon Matt]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/the-devil-went-down-to-awww-cmon-1beepisodes/episode024/index.htmlFri, 30 Sep 2016 00:00:00 GMTAudiommunity OrgAudiommunity loves Tasmanian devils, so we bite the s**t out of them... In this episode, we're talking about a contagious tumor that couldn't happen to a nicer species. No seriously, it really couldn't. Tasmanian devils bite each other on the face to say hello. WTF devils?No3542124fullAudiommunity loves Tasmanian devils, so we bite the s**t out of them... In this episode, we're talking about a contagious tumor that couldn't happen to a nicer species. No seriously, it really couldn't. Tasmanian devils bite each other on the face to say hello. WTF devils? Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 23 - If At First You Don't Succeed]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/if-at-first-you-dont-succeed-44bepisodes/episode023/index.htmlFri, 17 Jun 2016 00:00:00 GMTAudiommunity OrgThis week - Evidence that viruses drive the evolution of their hosts - who would have guessed? Matt struggles to remember how evolution works, and Kate and Kevin yell past each other about open peer review.No4606123This week - Evidence that viruses drive the evolution of their hosts - who would have guessed? Matt struggles to remember how evolution works, and Kate and Kevin yell past each other about open peer review. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 22 – So, a B-cell walks into a germinal center...]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/so-a-b-cell-walks-into-a-germinal-f27episodes/episode022/index.htmlWed, 11 May 2016 00:00:00 GMTAudiommunity OrgIn this episode, Matt and Kevin give in to aesthetics. This paper's just really pretty.No4653122fullIn this episode, Matt and Kevin give in to aesthetics. This paper's just really pretty. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 21 - Allergies Suck Less than Cancer]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/allergies-suck-less-than-cancer-ee1episodes/episode021/index.htmlTue, 26 Apr 2016 00:00:00 GMTAudiommunity OrgThis week, a guy gets a kiwi allergy from a bone marrow transplant from his sister, Matt envisions a magic mouse, and Kate peaces out after 20 min. Meanwhile, Kevin continues to be the only one drinking... that schtick may not last much longer.No3536121This week, a guy gets a kiwi allergy from a bone marrow transplant from his sister, Matt envisions a magic mouse, and Kate peaces out after 20 min. Meanwhile, Kevin continues to be the only one drinking... that schtick may not last much longer. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 20 – Bacteriophiles with Jesse Noar]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/bacteriophiles-with-jesse-noar-040episodes/episode020/index.htmlThu, 21 Apr 2016 00:00:00 GMTAudiommunity OrgSomething a bit different this episiode. Last month, we joined Jesse Noar, host of the excellent Bacteriophiles podcast to record an episode about oncolytic viruses (viruses that blow up cancer cells).No3441120fullSomething a bit different this episiode. Last month, we joined Jesse Noar, host of the excellent Bacteriophiles podcast to record an episode about oncolytic viruses (viruses that blow up cancer cells). Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 19 - J Lo Poop Pills]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/j-lo-poop-pills-efaepisodes/episode019/index.htmlThu, 17 Mar 2016 00:00:00 GMTAudiommunity OrgIn this episode, how parasitic worms alter in immunomodulatory effects of the gut microbiome. Also, Kate expresses her distaste for large datasets and animal experiments, and Matt proposes a weight loss company that will only market to identical twins.No4628119In this episode, how parasitic worms alter in immunomodulatory effects of the gut microbiome. Also, Kate expresses her distaste for large datasets and animal experiments, and Matt proposes a weight loss company that will only market to identical twins. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 18 – More cow... sirens?]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/more-cow-sirens-5efepisodes/episode018/index.htmlThu, 25 Feb 2016 00:00:00 GMTAudiommunity OrgIn this episode, we talk about the innate immune system's Trojan cow strategy - using a cyclic dinucleotide as a signaling molecule means that viruses can package the seeds of their own destruction.No4372118fullIn this episode, we talk about the innate immune system's Trojan cow strategy - using a cyclic dinucleotide as a signaling molecule means that viruses can package the seeds of their own destruction. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 17 - When your immune system is all up in it]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/when-your-immune-system-is-all-up-46depisodes/episode017/index.htmlThu, 28 Jan 2016 00:00:00 GMTAudiommunity OrgIn this episode we talk about lymphatics in the brain and why that's both obvious and not obvious. Meanwhile, Kate drinks disgusting smoothies and Kevin triggers Matt with a trigger warning.No3102117fullIn this episode we talk about lymphatics in the brain and why that's both obvious and not obvious. Meanwhile, Kate drinks disgusting smoothies and Kevin triggers Matt with a trigger warning. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 16 – Jimmy Carter's Brain on Drugs]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/jimmy-carters-brain-on-drugs-1bbepisodes/episode016/index.htmlWed, 13 Jan 2016 00:00:00 GMTAudiommunity OrgIn this episode, Matt and Kevin discuss checkpoint blockade cancer immunotherapy (wow, that's a mouthful). When cancer stamps down the breaks of the immune system, cutting the break line can allow T-cells to do their job.No3718116fullIn this episode, Matt and Kevin discuss checkpoint blockade cancer immunotherapy (wow, that's a mouthful). When cancer stamps down the breaks of the immune system, cutting the break line can allow T-cells to do their job. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 15 - The other DRACO]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/the-other-draco-681episodes/episode015/index.htmlMon, 21 Dec 2015 00:00:00 GMTAudiommunity OrgThis week, we're discussing DRACOs - not the Harry Potter character, a "new" class of antiviral therapeutics that links up the double-stranded RNA-binding part of one protein to the cell-death (apoPtosis)-activating part of a different protein.No4203115This week, we're discussing DRACOs - not the Harry Potter character, a "new" class of antiviral therapeutics that links up the double-stranded RNA-binding part of one protein to the cell-death (apoPtosis)-activating part of a different protein. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 14 – Matt got married, and we're talking about pregnancy]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/matt-got-married-and-were-talking-e6cepisodes/episode014/index.htmlWed, 09 Dec 2015 00:00:00 GMTAudiommunity OrgIn this episode, we're talking about the placental microbiome - that is, the bacteria that hang around a developing fetus in the womb. Wait, there are bacteria hanging around a developing fetus? Apparently!No4360114In this episode, we're talking about the placental microbiome - that is, the bacteria that hang around a developing fetus in the womb. Wait, there are bacteria hanging around a developing fetus? Apparently! Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 13 - GATACA]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/gataca-5e3episodes/episode013/index.htmlThu, 01 Oct 2015 00:00:00 GMTAudiommunity OrgIn this episode, we discuss the moral implications of doing experiments on babies without brains, and editing the genomes of unborn humans. I reveal my nature as a moral monster, and Kate can't resist bringing up Kim Kardashian's artificial selection of her own offspring.No4078113In this episode, we discuss the moral implications of doing experiments on babies without brains, and editing the genomes of unborn humans. I reveal my nature as a moral monster, and Kate can't resist bringing up Kim Kardashian's artificial selection of her own offspring. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 12 – Bee pollen is one of those hippy things]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/bee-pollen-is-one-of-those-hippy-332episodes/episode012/index.htmlThu, 16 Apr 2015 00:00:00 GMTAudiommunity OrgTo celebrate the return of the warm(ish) weather, we discuss a paper looking at immune responses to bee venom, and the underlying causes of environmental allergy.No3159112To celebrate the return of the warm(ish) weather, we discuss a paper looking at immune responses to bee venom, and the underlying causes of environmental allergy. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 11 - No, Not Seminol]]>and may play a role in suppressing a mother's immune response to a new fetus.

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/no-not-seminol-400episodes/episode011/index.htmlWed, 11 Mar 2015 00:00:00 GMTAudiommunity OrgA discussion about sCD38, a molecule that's secreted in mouse and human sperm, and may play a role in suppressing a mother's immune response to a new fetus.No3492111A discussion about sCD38, a molecule that's secreted in mouse and human sperm, and may play a role in suppressing a mother's immune response to a new fetus. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 10 – Taco shock syndrome]]>Also, Matt's bad hair day and a link between tacos and tampons.

Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/taco-shock-syndrome-496episodes/episode010/index.htmlWed, 28 Jan 2015 00:00:00 GMTAudiommunity OrgTurns out *Staphylococcus aureus* can evade the immune system by activating it. Also, Matt's bad hair day and a link between tacos and tampons.No3254110fullTurns out *Staphylococcus aureus* can evade the immune system by activating it. Also, Matt's bad hair day and a link between tacos and tampons. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 9 - I'd just like to second everything Abbie said]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/id-just-like-to-second-everything-8c5episodes/episode009/index.htmlThu, 04 Sep 2014 00:00:00 GMTAudiommunity OrgIn this episode, we're joined by Abbie Smith, a postdoctoral fellow studying HIV at Emory University, and author of the popular (and always wonderful) ERV blog.No452519In this episode, we're joined by Abbie Smith, a postdoctoral fellow studying HIV at Emory University, and author of the popular (and always wonderful) ERV blog. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 8 – Let's just make it more deadly]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/lets-just-make-it-more-deadly-b5cepisodes/episode008/index.htmlMon, 18 Aug 2014 00:00:00 GMTAudiommunity OrgKate and Kevin talk influenza and gain of function research. Should we be making flu more deadly?No494518fullKate and Kevin talk influenza and gain of function research. Should we be making flu more deadly? Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 7 - Hot Dog Buns, Hard Lines and Floppy Bits]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/hot-dog-buns-hard-lines-and-floppy-6b3episodes/episode007/index.htmlMon, 14 Jul 2014 00:00:00 GMTAudiommunity OrgAfter a hard day's work, sometimes you want to just kick your feet back and relax. Unfortunately, sometimes your CD8 T-cells want the same thing, even though they don't have feet.No460517After a hard day's work, sometimes you want to just kick your feet back and relax. Unfortunately, sometimes your CD8 T-cells want the same thing, even though they don't have feet. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 6 – Just a Huge Distraction]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/just-a-huge-distraction-c8fepisodes/episode006/index.htmlWed, 04 Jun 2014 00:00:00 GMTAudiommunity OrgIn this episode, Kevin talks with Pamela Ronald, professor of plant pathology at the University of California, Davis. Almost 20 years ago, Ronald discovered Xa21, a plant pattern recognition receptor that guards against bacterial infection. This receptor shares many features with Toll-like receptors, and the role of Xa21 was shown a year before TLRs were implicated in immunity.No226816fullIn this episode, Kevin talks with Pamela Ronald, professor of plant pathology at the University of California, Davis. Almost 20 years ago, Ronald discovered Xa21, a plant pattern recognition receptor that guards against bacterial infection. This receptor shares many features with Toll-like receptors, and the role of Xa21 was shown a year before TLRs were implicated in immunity. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 5 - When the Carnies Roll In]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/when-the-carnies-roll-in-137episodes/episode005/index.htmlWed, 14 May 2014 00:00:00 GMTAudiommunity OrgIn Episode 5, we're talking about neutrophils, and the special way they die.No3071In Episode 5, we're talking about neutrophils, and the special way they die. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 4 – Willy Nilly Brownian Motion]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/willy-nilly-brownian-motion-f33episodes/episode004/index.htmlFri, 25 Apr 2014 00:00:00 GMTAudiommunity OrgAfter a long absence, we're back! With an episode about the autoimmune disease multiple sclerosis and how immune cells navigate the around the body.No457414After a long absence, we're back! With an episode about the autoimmune disease multiple sclerosis and how immune cells navigate the around the body. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 3 - Immunologists' Dirty Little Secret]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/immunologists-dirty-little-secret-dd1episodes/episode003/index.htmlThu, 06 Mar 2014 00:00:00 GMTAudiommunity OrgToday, we're talking the *other* immunity (that both Kate and Kevin happen to study). Neglected for nearly one hundred years, the innate immune system is required for getting inflammation going, and without it, adaptive immunity wouldn't function.No5885Today, we're talking the *other* immunity (that both Kate and Kevin happen to study). Neglected for nearly one hundred years, the innate immune system is required for getting inflammation going, and without it, adaptive immunity wouldn't function. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 2 - Antibodies and Infantry]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/antibodies-and-infantry-835episodes/episode002/index.htmlMon, 24 Feb 2014 00:00:00 GMTAudiommunity OrgIn this episode, we're talking antibodies - what they are  and what they have to do with Vaccines. Also, we discuss efforts to use engineered antibodies to treat HIV.No519512fullIn this episode, we're talking antibodies - what they are  and what they have to do with Vaccines. Also, we discuss efforts to use engineered antibodies to treat HIV. Get full access to Audiommunity Org at audiommunity.substack.com/subscribe<![CDATA[Episode 1 - Everyone else’s kidneys]]>
Get full access to Audiommunity Org at audiommunity.substack.com/subscribe]]>https://audiommunity.substack.com/p/everyone-elses-kidneys-a58episodes/episode001/index.htmlThu, 30 Jan 2014 00:00:00 GMTAudiommunity OrgIn this episode, we're talking transplantation: Why is it so damned hard to transfer tumors between mice? Why do we have to go to extraordinary lengths to transplant kidneys between humans?No3031In this episode, we're talking transplantation: Why is it so damned hard to transfer tumors between mice? Why do we have to go to extraordinary lengths to transplant kidneys between humans? Get full access to Audiommunity Org at audiommunity.substack.com/subscribe