Beximco Pharma

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mkd@bpl.net (Administrator) — Sun, 11 Dec 2011 05:35:58 GMT

Exchanges where quoted and traded

AIM (GDRs* Only)
Dhaka Stock Exchange ( Ordinary Share )
Chittagong Stock Exchange ( Ordinary Share )

*GDRs are not quoted and traded in Dhaka and Chittagong Stock Exchanges

Number of AIM securities in issue:	::	56,457,439 GDRs
Percentage free float	::	100%
Percentage of shares not held in public hands	::	0
Number of shares held in treasury	::	0
Percentage of shares held in treasury	::	0

The identity and percentage holding of significant shareholders (i.e., holder of 3% or more AIM Securities in issue) are as follows:-

Significant Shareholders	No. of GDRs held	Percentage of shares held
HSBC Global Custody Nominees ( UK ) Limited	3.79m	6.17%
Credit Suisse Client Nominees (UK) Limited	8.63m	15.3%
Pershing Nominees Ltd.	6.97m	12.4%
Vidacos Nominees Ltd.	2.70m	4.8%

These however do not include information relating to AIM Securities cleared through Eoroclear that does not disclose holding because of secrecy under the Belgian Law; and also AIM Securities held in certificated form (i.e., GDRs physically in the possession of the GDRholders, not enabling us to furnish the name, address and number of GDRs held by such holders).

Cinarex-D Ophthalmic suspension

mkd@bpl.net (Administrator) — Wed, 07 Dec 2011 11:49:35 GMT

…to fight infections and inflammations together

Dexamethasone is glucocorticoid. It has an anti-inflammatory and anti-allergic action. It is used topically in the treatment of inflammatory conditions of the anterior segment of the eye. The efficacy of corticosteroids for the treatment of inflammatory conditions of the eye is well established. It works by reducing swelling. Tobramycin is an aminoglycoside antibiotic for topical administration to the eyes. It works by stopping the growth of bacteria by inhibiting protein synthesis. Tobramycin provide antibacterial protection against susceptible becteria.

Cinarex Eye drops

mkd@bpl.net (Administrator) — Wed, 07 Dec 2011 11:42:32 GMT

…a safe antibiotic for delicate patients

Cinarex (Tobramycin) is a water soluble aminoglycoside antibiotic active against a wide variety of ophthalmic infections. It is indicated for the treatment of external infections of the eye and its appendages such as bacterial conjunctivitis, keratitis, corneal ulcer caused by susceptible bacteria.Tobramycin ophthalmic preparation is safe and effective for use in children over 2 months of age.

The most frequent adverse reactions to Tobramycin are localized ocular toxicity and hypersensitivity, including lid itching and swelling and conjunctival erythema. These reactions are rare and occur in less than 3% of patients treated. Cinarex® Eye Drops: Plastic dropper bottle contains 5 ml sterile eye drops & each ml contains Tobramycin USP 3 mg.

Neofloxin D Eye & Ear Drops

mkd@bpl.net (Administrator) — Mon, 28 Nov 2011 05:00:07 GMT

Ciprofloxacin 0.3% and Dexamethasone 0.1%

…works together against infectious inflammation

Dexamethasone is glucocorticoid. It has an anti-inflammatory and anti-allergic action.Ciprofloxacin has cidal and inhibitory activities against bacteria which result from an interference with DNA gyrase, an enzyme needed by the bacterium for the synthesis of DNA.This combination eye drop is indicated for the treatment of steroid responsive inflammatory ocular conditions where bacterial infections or risk of bacterial infections co-exist. It is also indicated for the treatment of ear infections accompanied by inflammation such as otitis externa, otitis media and chronic suppurative otitis media etc. Neofloxin®-D Eye/Ear Drops: Plastic dropper bottle contains 5 ml sterile suspension each ml contains Dexamethasone USP 1 mg and Ciprofloxacin Hydrochloride USP equivalent to Ciprofloxacin 3 mg.

Regulatory Approvals

mkd@bpl.net (Administrator) — Mon, 21 Nov 2011 09:36:20 GMT

Over the years Beximco Pharma has established itself as a trusted source for prescription and OTC drugs. It always strives for quality, not only in the finished products but also in the manufacturing process itself. Beximco Pharma’s manufacturing facilities have undergone satisfactory audits by global regulatory bodies and thus have been awarded regulatory approvals including:

GMP clearance from Therapeutic Goods Administration (TGA) Australia for OSD, MDI and Spray.
GMP certification from Gulf Central Committee for Drug Registration, Executive Board of the Health Ministers’ Council of GCC states.
GMP certification from ANVISA, Brazil (Agência Nacional de Vigilância Sanitária)
GMP certification from INVIMA, Colombia (Instituto Nacional de Vigilancia de Medicamentos y Alimentos)
GMP certification from AGES, Austria (Austrian Agency for Health and Food Safety)
Qualified by UNICEF (MDI & OSD)
Qualified by Asthma Drug Facility (ADF), France (MDI)

GMP accreditation audit by an EMA regulatory authority was completed for the OSD and Ophthalmology units, and inspections and approvals from UK MHRA and US FDA are anticipated.

Third Quarter Report 2011

mkd@bpl.net (Administrator) — Tue, 01 Nov 2011 12:43:00 GMT

Open/ Download

Napa Extra

mkd@bpl.net (Administrator) — Tue, 01 Nov 2011 09:52:42 GMT

Napa® Extra is a mild analgesic and antipyretic formulated to give extra relief from pain and fever. It is a preparation of Paracetamol 500 mg and caffeine 65 mg. Paracetamol produces analgesia and Caffeine acts as an analgesic adjuvant and enhances the efficacy of Paracetamol.

Napa® Extra is recommended for the treatment of most painful and febrile conditions, for example, headache, including migraine, backache, toothache, rheumatic pain and dysmenorrhoea, and the relief of the symptoms of colds, influenza and sore throat.

Beximco Pharma Announces Third Quarter Financial Statements, 2011

mkd@bpl.net (Administrator) — Sun, 30 Oct 2011 05:03:37 GMT

We are pleased to present the un-audited Financial Statements of Beximco Pharmaceuticals Ltd.for the third quarter ended September 30, 2011 as per Securities and Exchange CommissionNotification No. SEC/CMRRCD/2008-183/Admin/03-34 dated September 27, 2009.

Press Releases September 30, 2011

NapaDol

mkd@bpl.net (Administrator) — Wed, 12 Oct 2011 04:49:58 GMT

(Paracetamol 325mg & Tramadol Hydrochloride 37.5mg Tablet)

Fixed dose combination of Paracetamol & Tramadol provides better pain relief than the individual molecules. Moreover, after surgery, tramadol inj. often prescribed to relieve post operative pain. But, injection generally given for short time. In this case this combination would be effective as maintenance therapy of post operative pain. Apart from this, paracetamol & tramadol combination shows excellent efficacy against painful osteoarthritis flare, traumatic pain & low back pain. Results of the published clinical literature suggest that Tramadol/Paracetamol, by reducing the incidence of adverse events, provides benefits for patients. Till the launching of NapaDol, Paracetamol & Tramadol were being used separately for the management of pain. Combination of Paracetamol & Tramadol provides dosage convenience to patient.

Ensures excellent management of pain
Ensures excellent option of osteoarthritis pain
Ensures effective management of painful osteoarthritis flare
Ensures an effective option for chronic LBP
Ensures effective option in breakthrough cancer pain relief
Ensures safety of treatment

Tetrace

mkd@bpl.net (Administrator) — Wed, 12 Oct 2011 04:45:52 GMT

Tetrace
(Cefepime Injection)
Cefepime is a fourth-generation cephalosporin antibiotic. Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria than third-generation cephalosporin. Cefepime has good activity against important pathogens including Pseudomonas aeruginosa, Staphylococcus aureus and multiple drug resistant Streptococcus pneumoniae. A particular strength is its activity against Enterobacteriaceae, whereas other cephalosporins are degraded by many plasmid and chromosome-mediated beta-lactamases. Cefepime is stable and is a front line agent when infection with Enterobacteriaceae is known or suspected. Cefepime is usually reserved to treat moderate-severe nosocomial pneumonia, infections caused by multi-resistant microorganisms (e.g. Pseudomonas aeruginosa) and empirical treatment of febrile neutropenia.

Rapid entry into bacterial cell wall due to having a Zwitter ion in its structure
Greater resistance to degradation by beta-lactamase
Enhanced affinity to PBP(Penicillin Binding Protein)
Lower MIC value than Ceftriaxone to Gram negative bacteria

Beximco Pharma

Share Information

Exchanges where quoted and traded

Cinarex-D Ophthalmic suspension

Cinarex Eye drops

Neofloxin D Eye & Ear Drops

Regulatory Approvals

Third Quarter Report 2011

Napa Extra

Beximco Pharma Announces Third Quarter Financial Statements, 2011

NapaDol

Tetrace

Cinarex-D Ophthalmic suspension