tag:blogger.com,1999:blog-4697350873058183760Wed, 21 Jun 2023 15:11:29 +0000BiologicsRheumatoid ArthritisPsoriatic ArthritisTNF BlockersMedical SchemesArthritis FoundationJuvenile ArthritisAnkylosing spondylitisBiosimilarsEnbrelHumiraPsoriasisRARevelexSABIOSide EffectsTumor Necrosis Factor (TNF)cancerAdalimumabAnnals of the Rheumatic DiseasesApremilastArthritisAtrhritisBWGBilogicsBiologics Working GroupCHATCostCytokinesDMARDDepressionDiscoveryErasmusEtanerceptFDAHeart RisksInfliximabKeneretMaptheraMelanomaOtezlaPHANGOPMBPharmaceutical CompaniesRA AlgorithmRituxanSirukumabcardiovascularfundingheart attackmethotrexatepatch; biologicsstrokeIn recent years, there have been promising advances in treating rheumatoid arthritis -- especially for those people who do not respond to disease-modifying drugs. The most important advance has been the development of a group of drugs called biologic response modifiers or biologics. This site has been established as a mouthpiece to the arthritis sufferer; providing regular updates of trends on biologics and developments on the availability thereof in Southern Africa.http://www.biologics.co.za/noreply@blogger.com (Andre Augustyn)Blogger23125tag:blogger.com,1999:blog-4697350873058183760.post-6007741606259593411Sat, 11 Apr 2015 13:09:00 +00002015-04-11T15:09:39.157+02:00BiologicsBiosimilars Biological Products Many of today’s important medications are biological products. Biological products are made from living organisms. The material they are made from can come from many sources, including humans, animals and microorganisms such as bacteria or yeast. Biological products are manufactured through biotechnology, derived from natural sources or, in some cases, produced http://www.biologics.co.za/2015/04/information-for-consumers-biosimilar.htmlnoreply@blogger.com (Andre Augustyn)0tag:blogger.com,1999:blog-4697350873058183760.post-5531824114028825571Sat, 11 Apr 2015 13:00:00 +00002015-04-11T15:00:09.003+02:00BiologicsPsoriasisPsoriatic Arthritis GBI Research has released its pharma report "Systemic Psoriasis Therapeutics in Major Developed Markets to 2020 - Continued Uptake of Biologics and Novel Pipeline Drugs to Drive Growth". The systemic psoriasis market is forecast to grow substantially over the forecast period from $5.0 billion in 2013 to $10.4 billion in 2020, across the eight major markets. This growth will be driven by a http://www.biologics.co.za/2015/04/psoriasis-therapeutics-market-expected.htmlnoreply@blogger.com (Andre Augustyn)0tag:blogger.com,1999:blog-4697350873058183760.post-109465603413645095Tue, 25 Mar 2014 05:45:00 +00002014-03-25T07:46:12.769+02:00ApremilastFDAOtezlaTumor Necrosis Factor (TNF) FDA approves Otezla to treat psoriatic arthritis The U.S. Food and Drug Administration today approved Otezla (apremilast) to treat adults with active psoriatic arthritis (PsA). PsA is a form of arthritis that affects some people with psoriasis. Most people develop psoriasis first and are later diagnosed with PsA. Joint pain, stiffness and swelling are the main signs and symptoms of PsA. http://www.biologics.co.za/2014/03/fda-approves-otezla-to-treat-psoriatic.htmlnoreply@blogger.com (Andre Augustyn)0tag:blogger.com,1999:blog-4697350873058183760.post-7639556170379050858Fri, 07 Feb 2014 09:10:00 +00002014-02-07T11:10:49.054+02:00BiologicscancerMelanomaRheumatoid ArthritisTNF Blockers TNF blockers are not associated with an increased risk of most types of cancer -- except nonmelanoma skin cancer and malignant melanoma. TNF blockers are biologic drugs used to treat conditions such as rheumatoid arthritis, psoriasis, and other autoimmune conditions. According to a report in Rheumatology News, the risk for cancer with the use of TNF blockers is about 6 per 1,000. With http://www.biologics.co.za/2014/02/tnf-blockers-used-for-rheumatoid.htmlnoreply@blogger.com (Andre Augustyn)0tag:blogger.com,1999:blog-4697350873058183760.post-7052605396155043105Sat, 01 Feb 2014 14:52:00 +00002014-02-01T16:52:20.576+02:00ArthritisBiologicsDepressionSide Effects Cordingley L. Arthritis Care Res. 2013;doi:10.1002/acr.22249. High levels of depression and anxiety were reported by patients with active rheumatoid arthritis who were awaiting biologic therapy, according to study results.  “This is the first study of its kind in patients with high levels of active disease, and suggests that routinely assessing a patient’s moods and beliefs — separate to http://www.biologics.co.za/2014/02/ra-patients-awaiting-biologic-therapy.htmlnoreply@blogger.com (Andre Augustyn)0tag:blogger.com,1999:blog-4697350873058183760.post-5237171319570697990Thu, 04 Apr 2013 11:43:00 +00002013-04-04T13:51:45.909+02:00BiologicsBiosimilars The current situation and future prospects for biosimilars is similar to that of small molecule drugs, according to an analysis by Research and Markets: they get to benefit from patent expiry.  On this basis, prospects for biosimilars might look good, with the vast majority of leading originator brands in the global biologics market expected to lose some degree of protection by 2019.  But http://www.biologics.co.za/2013/04/current-and-future-prospects-for.htmlnoreply@blogger.com (Andre Augustyn)0tag:blogger.com,1999:blog-4697350873058183760.post-8675809472039626631Sat, 25 Aug 2012 12:41:00 +00002012-08-25T14:44:56.176+02:00BiologicsRheumatoid ArthritisSirukumabTNF Blockers Published 24th August 2012 - PRB Staff Writer (http://clinicaltrials.pharmaceutical-business-review.com) Biologics (Ireland) has begun dosing in the Phase 3 program evaluating sirukumab (CNTO 136) as part of a collaboration with GlaxoSmithKline (GSK).  Sirukumab is a human anti-interleukin (IL)-6 monoclonal antibody in Phase 3 development for the treatment of adults with moderatelyhttp://www.biologics.co.za/2012/08/janssen-biologics-commences-phase-3.htmlnoreply@blogger.com (Andre Augustyn)0tag:blogger.com,1999:blog-4697350873058183760.post-9114737893207458560Wed, 31 Aug 2011 09:20:00 +00002011-08-31T11:20:44.118+02:00Heart RisksPsoriasisPsoriatic ArthritisSource: http://www.huffingtonpost.com/2011/08/24/psoriasis-drugs-heart-risks-biologics_n_935462.html For people with severe cases of psoriasis, the injectable drugs known as biologics can provide much-needed relief from the itchy, http://www.biologics.co.za/2011/08/psoriasis-drugs-not-linked-to-increased.htmlnoreply@blogger.com (Andre Augustyn)0tag:blogger.com,1999:blog-4697350873058183760.post-1298620476988826962Wed, 31 Aug 2011 09:12:00 +00002011-08-31T11:12:18.018+02:00BiologicsRARheumatoid Arthritis World News | August 30, 2011   Lynne Taylor         Patients wait 18 months after first experiencing any symptoms of rheumatoid arthritis (RA) before going to see their doctor, and they wait an average of seven years before their doctor starts treating with them a biologic drug, says a new study. This is despite findings which show that patients who are being http://www.biologics.co.za/2011/08/ra-patients-wait-seven-years-before.htmlnoreply@blogger.com (Andre Augustyn)1tag:blogger.com,1999:blog-4697350873058183760.post-4498762547580729960Fri, 05 Aug 2011 07:18:00 +00002011-08-05T09:19:22.322+02:00patch; biologicsJuly 11, 2011|By Lindsey Hoshaw, Globe Correspondent Frank Bobe, SpringLeaf chief executive, said the device gives control… (Jonathan Wiggs/Globe Staff) Patients who receive frequent intravenous injections to treat chronic illness typically endure arduous hospital visits. A new device could change that. SpringLeaf Therapeutics is developing a drug-filled patch patients can attach to their skin tohttp://www.biologics.co.za/2011/08/patch-may-replace-iv-drug-infusions.htmlnoreply@blogger.com (Andre Augustyn)0tag:blogger.com,1999:blog-4697350873058183760.post-7227277595287253563Wed, 25 May 2011 11:46:00 +00002011-05-25T13:46:17.644+02:00AtrhritisBilogicsIf you suffer from chronic pain, you may have to try a variety of treatments before you find the right ones for your symptoms. Some treatments may include pain and anti-inflammatory medications, diet and lifestyle changes, physical, occupational and support therapies. If these don't provide the relief you need, there's one more option that might relieve your chronic pain--biologics.  http://www.biologics.co.za/2011/05/is-it-time-to-take-biologics.htmlnoreply@blogger.com (Andre Augustyn)0tag:blogger.com,1999:blog-4697350873058183760.post-1438316016204482777Mon, 21 Dec 2009 13:04:00 +00002009-12-21T16:18:23.122+02:00Ankylosing spondylitisBiologicsMedical SchemesPMBPsoriatic ArthritisRheumatoid ArthritisDespite the recent South African test case (Erasmus vs Discovery) resulting in the inclusion of biologics as the current treatment algorithm for Rheumatoid Arthritis, this does unfortunately not change the position for a large percentage individuals identified with other forms of arthritis. As an individual suffering from severe psoriatic arthritis that has evolved to ankylosis spondylitis, http://www.biologics.co.za/2009/12/despite-recent-south-african-test-case.htmlnoreply@blogger.com (Andre Augustyn)5tag:blogger.com,1999:blog-4697350873058183760.post-8872664671552645088Sun, 29 Nov 2009 15:36:00 +00002009-11-29T17:48:41.295+02:00BiologicsDiscoveryErasmusfundingMedical SchemesRA AlgorithmRheumatoid Arthritis Full funding of biologic drugs for medical scheme members with severe rheumatoid arthritis (RA) is now a reality.In a surprising about turn, Discovery recently retracted their second appeal against two earlier rulings by the Council for Medical Schemes, which ordered them to fund their member, Sylvia Erasmus[1], in full for the use of the anti-rheumatic biologic, Enbrel, after previous treatmenthttp://www.biologics.co.za/2009/11/full-funding-for-arthritis-biologics.htmlnoreply@blogger.com (Andre Augustyn)2tag:blogger.com,1999:blog-4697350873058183760.post-3499250972984702994Wed, 29 Oct 2008 09:12:00 +00002008-10-29T11:25:28.261+02:00cancerRheumatoid ArthritisTNF BlockersTNF-antagonists, drugs widely used to treat rheumatoid arthritis (RA), don't appear to cause cancer, say Spanish researchers who analyzed data on more than 4,000 RA patients treated with the biologics. These drugs, which have been used since 1998 and given to more than 600,000 people worldwide, interfere with biologic substances that cause or worsen inflammation in RA patients. But it's been http://www.biologics.co.za/2008/10/biologics-dont-raise-cancer-risk-in-ra.htmlnoreply@blogger.com (Andre Augustyn)1tag:blogger.com,1999:blog-4697350873058183760.post-2826390598346800357Thu, 06 Mar 2008 09:24:00 +00002008-03-06T11:35:14.553+02:00cardiovascularheart attackmethotrexateRARheumatoid ArthritisstrokeTNF BlockersPatients prescribed drugs to treat rheumatoid arthritis could be at a reduced risk of heart attacks and strokes, according to a study published today in the open access journal Arthritis Research & Therapy.An international team of researchers led by Antonio Naranjo of the University of Las Palmas de Gran Canaria, Spain, and colleagues in Argentina, Europe, and the USA have analyzed data from the http://www.biologics.co.za/2008/03/arthritis-medications-reduce-risk-of.htmlnoreply@blogger.com (Andre Augustyn)4tag:blogger.com,1999:blog-4697350873058183760.post-2317609099482447591Mon, 03 Sep 2007 07:01:00 +00002007-09-03T09:25:15.574+02:00AdalimumabAnnals of the Rheumatic DiseasesEtanerceptInfliximabTumor Necrosis Factor (TNF)NEW YORK (Reuters Health) - Patients with rheumatoid arthritis who fail to respond to one of the biological drugs will often have a better response to a second drug within the same class, Danish researchers report in the Annals of the Rheumatic Diseases."Our data show that patients with rheumatoid arthritis benefit from switching to a second biologic drug," lead investigator Dr. Elisabeth Hjardemhttp://www.biologics.co.za/2007/09/drug-switch-may-benefit-arthritis.htmlnoreply@blogger.com (Andre Augustyn)0tag:blogger.com,1999:blog-4697350873058183760.post-4441517422874013082Wed, 22 Aug 2007 12:04:00 +00002007-08-22T14:17:47.187+02:00Ankylosing spondylitisBiologicsCostJuvenile ArthritisMedical SchemesPharmaceutical CompaniesPsoriatic ArthritisRheumatoid ArthritisBiologics, the new ‘wonder-drug’ in the fight against arthritis, offers the hope of partial or complete remission to people with previously incurable systemic arthritis diseases like rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and juvenile arthritis. But there is no getting around the fact that biologics are very expensive, typically costing 20 times more per patient per dayhttp://www.biologics.co.za/2007/08/cost-of-biologics-what-holds-answer.htmlnoreply@blogger.com (Andre Augustyn)0tag:blogger.com,1999:blog-4697350873058183760.post-2711879265322411049Fri, 17 Aug 2007 11:14:00 +00002007-08-17T09:44:59.836+02:00BiologicsEnbrelHumiraPsoriatic ArthritisRevelexRheumatoid ArthritisBiologics are genetically engineered proteins derived from human genes. They are designed to either inhibit or supplement specific components of the immune system called cytokines. These cytokines play a pivotal role in either fueling or suppressing inflammation (a key component in several forms of arthritis, such as rheumatoid arthritis and psoriatic arthritis).In recent years, there have been http://www.biologics.co.za/2007/07/what-is-biologics.htmlnoreply@blogger.com (Andre Augustyn)0tag:blogger.com,1999:blog-4697350873058183760.post-7361794930122718003Tue, 07 Aug 2007 07:37:00 +00002007-08-17T09:45:20.554+02:00Biologics Working GroupBWGMedical SchemesStar Editorial (August 06, 2007 Edition 2)What price the milk of human kindness? That's a question we can ask in the wake of a study that challenges claims by medical aid schemes that highly effective biological drugs are too expensive to provide.Biologics are target-specific treatments - such as the breast cancer drug Herceptin - that attack particular cells, cannot be manufactured and are grownhttp://www.biologics.co.za/2007/08/battle-of-profit-vs-health.htmlnoreply@blogger.com (Andre Augustyn)1tag:blogger.com,1999:blog-4697350873058183760.post-1224955873937972869Sun, 29 Jul 2007 09:48:00 +00002007-08-03T12:03:17.312+02:00EnbrelHumiraKeneretMaptheraRevelexRituxanSide EffectsTNF BlockersThese biologic response modifiers block an immune system protein called tumor necrosis factor, which acts as an inflammatory agent in some types of arthritis. By targeting this protein, TNF blockers can help reduce pain, morning stiffness and swollen joints. Some people experience side effects during or shortly after these drugs are injected, including chest pain, dizziness and difficulty http://www.biologics.co.za/2007/07/tumor-necrosis-factor-tnf-blockers-most.htmlnoreply@blogger.com (Andre Augustyn)1tag:blogger.com,1999:blog-4697350873058183760.post-2745894582499373672Sun, 17 Jun 2007 06:42:00 +00002007-08-17T09:30:12.972+02:00Arthritis FoundationBiologicsCHATDMARDJuvenile ArthritisChildren's Arthritis Trust (CHAT) offers hope to kids crippled by arthritis.To help treatment resistant children and teenagers in public healthcare who have not responded to the conventional drugs used for treating this crippling and devastating illness, The Arthritis Foundation has launched a special Children's Arthritis Trust called CHAT (Children Have Arthritis Too). The funds raised by this http://www.biologics.co.za/2007/05/childrens-arthritis-trust-chat.htmlnoreply@blogger.com (Andre Augustyn)2tag:blogger.com,1999:blog-4697350873058183760.post-3848816303600777185Thu, 07 Jun 2007 13:44:00 +00002007-08-17T09:29:49.372+02:00Arthritis FoundationBiologicsCytokinesRheumatoid ArthritisSABIOThere is a revolutionary new arthritis drug on the market, but some South African medical schemes seem unwilling to pay for it.A ground-breaking new class of drugs, known as biologics, offers the hope of partial or complete remission to people with previously incurable systemic arthritis diseases like rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and juvenile arthritis.Howeverhttp://www.biologics.co.za/2007/05/ra-drug-too-costly-say-sa-schemes.htmlnoreply@blogger.com (Andre Augustyn)0tag:blogger.com,1999:blog-4697350873058183760.post-6085975324184053899Sun, 06 May 2007 14:10:00 +00002007-08-06T16:28:41.042+02:00Arthritis FoundationBiologicsJuvenile ArthritisPHANGOSABIO "The Arthritis Foundation has taken up the challenge to ensure that people with arthritis will no longer be ignored when political or medical decisions are being taken that affect us." For too long we have merely accepted the word of our doctors, the ruling of our medical aids, or the service we get in the public health facilities, believing that one little lone voice won't achieve much in the http://www.biologics.co.za/2007/05/people-with-arthritis-giving-voice-to.htmlnoreply@blogger.com (Andre Augustyn)0