http://clincalc.com/blog Clinical tools and calculators for medical professionals Sun, 23 Aug 2015 12:15:29 +0000 en-US hourly 1 http://wordpress.org/?v=4.3.1 http://clincalc.com/blog/2015/08/new-colistin-colistimethate-sodium-calculator/ http://clincalc.com/blog/2015/08/new-colistin-colistimethate-sodium-calculator/#comments Sun, 23 Aug 2015 12:15:29 +0000 http://clincalc.com/blog/?p=339 Colistin (in the form of colistimethate sodium, or CMS, in the United States) is an older, last-line agent for multidrug-resistant gram-negative infections.  Because of colistin’s complex pharmacokinetics and for historical reasons, there is a paucity of data regarding its dosing in patients with severe gram negative infections, particularly for those with concurrent renal dysfunction. In one of […]]]> http://clincalc.com/blog/2015/08/new-colistin-colistimethate-sodium-calculator/feed/ 0 http://clincalc.com/blog/2015/07/vitamin-d2-ergocalciferol-vs-d3-cholecalciferol/ http://clincalc.com/blog/2015/07/vitamin-d2-ergocalciferol-vs-d3-cholecalciferol/#comments Sun, 19 Jul 2015 18:38:16 +0000 http://clincalc.com/blog/?p=327 In the United States, vitamin D supplementation is primarily available as vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). Although these two have historically been considered interchangeable and equipotent, the current body of literature strongly supports the preference of Vitamin D3 (cholecalciferol) over D2 (ergocalciferol). Vitamin D2 versus Vitamin D3 Vitamin D3 (cholecalciferol) is produced by […]]]> http://clincalc.com/blog/2015/07/vitamin-d2-ergocalciferol-vs-d3-cholecalciferol/feed/ 0 http://clincalc.com/blog/2015/06/vancomycin-calculator-eoip/ http://clincalc.com/blog/2015/06/vancomycin-calculator-eoip/#comments Sun, 07 Jun 2015 16:33:11 +0000 http://clincalc.com/blog/?p=302 We’re releasing a major update to the calculation for our popular vancomycin calculator today. Briefly, the new update implements more advanced calculations when adjusting a vancomycin dose based on a trough level. Drug Elimination during Vancomycin Infusion When adjusting vancomycin based on a trough level, pharmacokinetic textbooks recommend estimating a vancomycin peak level using the […]]]> http://clincalc.com/blog/2015/06/vancomycin-calculator-eoip/feed/ 0 http://clincalc.com/blog/2015/04/icu-trials-passes-100-landmark-studies/ http://clincalc.com/blog/2015/04/icu-trials-passes-100-landmark-studies/#comments Sun, 19 Apr 2015 18:25:21 +0000 http://clincalc.com/blog/?p=296 ClinCalc.com is proud to announce that ICU Trials by ClinCalc, a mobile application that summarizes landmark critical care trials, has surpassed 100 studies in the app database! With our most recent update on April 18th, the following recent and historic landmark trials were added: MIDEX (2012): Dexmedetomidine vs. midazolam for mechanical ventilation PAC-Man (2005): Efficacy […]]]> http://clincalc.com/blog/2015/04/icu-trials-passes-100-landmark-studies/feed/ 2 http://clincalc.com/blog/2015/04/speed-up-video-playback-of-the-top-250-drugs-online-course/ http://clincalc.com/blog/2015/04/speed-up-video-playback-of-the-top-250-drugs-online-course/#comments Fri, 10 Apr 2015 01:52:11 +0000 http://clincalc.com/blog/?p=290 At ClinCalc.com, we’re huge fans of listening and watching educational content at a faster than normal pace. Unfortunately, the video provider used for The Top 250 Drugs (online drug therapy course) does not allow for the ability to change playback speed. Given our dedication to high-yield, rapid foundational learning, we’ve decided to build a free […]]]> http://clincalc.com/blog/2015/04/speed-up-video-playback-of-the-top-250-drugs-online-course/feed/ 0 http://clincalc.com/blog/2015/02/the-top-250-drugs-announcement/ http://clincalc.com/blog/2015/02/the-top-250-drugs-announcement/#comments Mon, 16 Feb 2015 18:11:10 +0000 http://clincalc.com/blog/?p=279 ClinCalc.com has been a bit quiet over the past year.  Our Twitter account has been mute, email updates rare, and website updates sparse. Why the radio silence? We’ve been diligently working on an exciting new product for the past year.  Quite literally, HUNDREDS of hours have been poured into the conception, creation, and implementation of this amazing new product. […]]]> http://clincalc.com/blog/2015/02/the-top-250-drugs-announcement/feed/ 0 http://clincalc.com/blog/2014/03/incredible-update-mobile-vancomycin-calculator-androidios/ http://clincalc.com/blog/2014/03/incredible-update-mobile-vancomycin-calculator-androidios/#comments Sat, 29 Mar 2014 22:04:40 +0000 http://clincalc.com/blog/?p=249 Advanced vancomycin pharmacokinetics equations has never been this easy. Our original Android-based Vancomycin Calculator was released in July 2011, followed a year later by our iPhone version.  In both mobile technology and the features of the ClinCalc.com website, a lot has changed in the last 2.5+ years. Today, we’re proud to announce a full redesign […]]]> http://clincalc.com/blog/2014/03/incredible-update-mobile-vancomycin-calculator-androidios/feed/ 0 http://clincalc.com/blog/2014/03/nejm-albios-review-failure/ http://clincalc.com/blog/2014/03/nejm-albios-review-failure/#comments Fri, 21 Mar 2014 03:01:57 +0000 http://clincalc.com/blog/?p=238 The New England Journal of Medicine released three landmark trials this week.  Each trial directly addresses controversies in sepsis management that have been debated for a decade or longer: high versus low MAP goals (SEPSISPAM), a challenge to early goal-directed therapy (ProCESS), and albumin replacement (ALBIOS). These trials will undoubtedly have a significant impact on […]]]> http://clincalc.com/blog/2014/03/nejm-albios-review-failure/feed/ 4 http://clincalc.com/blog/2013/12/visualizing-the-ascvd-pooled-cohort-equations/ http://clincalc.com/blog/2013/12/visualizing-the-ascvd-pooled-cohort-equations/#comments Mon, 16 Dec 2013 00:28:42 +0000 http://clincalc.com/blog/?p=215 The newest ACC/AHA ASCVD Pooled Cohort Equations has been a very hot topic lately.  Our free web-based ASCVD tool and mobile applications have been very well received.  A number of ClinCalc readers have asked for a better understanding of the Pooled Cohort Equations — how is an ASCVD calculated?  How “strong” is each risk factor? […]]]> http://clincalc.com/blog/2013/12/visualizing-the-ascvd-pooled-cohort-equations/feed/ 3 http://clincalc.com/blog/2013/11/ascvd-risk-calc-mobile-and-web-based/ http://clincalc.com/blog/2013/11/ascvd-risk-calc-mobile-and-web-based/#comments Sat, 23 Nov 2013 12:49:32 +0000 http://clincalc.com/blog/?p=205 At ClinCalc, we’re very proud to announce the availability of both a web-based and mobile-based (Android/iOS) 10-year ASCVD Risk Calculator (also termed the Pooled Cohort Equations Calculator).  This risk assessment tool is recommended by the newly published 2013 ACC/AHA cholesterol guidelines to estimate 10-year risk of atherosclerotic cardiovascular disease (ASCVD). Sweeping Changes to Cholesterol Guidelines These new […]]]> http://clincalc.com/blog/2013/11/ascvd-risk-calc-mobile-and-web-based/feed/ 4