Anthropological records show that the agricultural growing of crops such as grains and animal husbandry only began about 10,000 years ago. From an evolutionary genetic perspective this is only a short period of time for adaptation to take place on a genetic level to a change in our diet from that of a hunter and gatherer and only represents less than 1% of total human evolution with 99% being devoted to a hunter-gatherer diet. It has been speculated that the rise in chronic disease is a misalignment between ancient genomes that humans possess and their modern diets. These researchers have suggested that a diet most suitable for modern humans to consume is the hunter-gatherer diet that has been the most prevalent in our entire 2 million year history and thus the diet we are genetically designed to ingest. In addition around the same time, about 10,000 years ago another discovery was made which was the cooking of certain foods such as potato made them edible which had not been previously eaten until this discovery was made.

A paleolithic diet typically includes lean meat, fish, shellfish, seasonal fruit and vegetables, roots, eggs, nuts and seeds. It excludes all other foods such as grains including bread, pasta and noodles, dairy products, potatoes, salt, yeast, refined sugars and fats which all became staple foods with the agricultural revolution and the cooking of foods. The consumption of milk only occurred with the domestication of sheep, goats and cows around 10,000 years ago with the first evidence of dairy consumption being only 6000 years ago. The consumption of grains began about 11,000 but not until recently was used as an all year round staple, not to mention only within the last 200 years or so the milling of grains changed to produce refined white flour. Analysis shows that 70% of a typical western diet would not have been consumed pre-agricultural boom and thus is relatively foreign to our genes.

As a practitioner I see many patients with chronic illnesses with food being a contributing factor to their ill health. Dairy, gluten, yeast are the main culprits which should be avoided as we are not genetically designed to ingest them.

Carbohydrates, including sugars, are responsible for the release of insulin from your pancrease which then aids their transport into muscle and fat cells to be burnt off for energy production. As your cells become resistant to insulin your body reacts by producing more and more of it in order to maintain your blood sugar levels. This is known as insulin resistance which is the stage that precedes diabetes. Insulin resistance is harmful to your body as the spikes and crashes of blood glucose levels disrupt sex hormones, increases adrenal cortisol stress response, cause the over production of inflammatory hormones known as ecosonoids which increase inflammation in the body which is the precursor to cardiovascular disease, not to mention weight gain, increased blood pressure, etc, etc. It is therefore vital to maintain low insulin levels and thus a diet relatively low in sugar and carbohydrates is also recommended.

For those who have developed their clairsentience, and thus able to feel the effects of these foods on their body energetically, will know they are very harmful energetically also. They add dampness to the body, bury emotions and prevent true vitality.

As a general recommendation we recommend the following diet:

Foods Containing Protein

We recommend a reasonably high protein intake up to 60% of your calories coming from a lean protein source. Animal foods are rich in protein include: chicken, turkey, fish and sea food, eggs, lamb and beef (eat sparingly). Other acceptable protein sources are beans, tofu, and low-fat meat substitutes. Only eat grass fed red meats as grain fed meats may be contaminated with fungi and their mycotoxins from the grains they are fed.

Vegetables
One can include a large quantity of vegetables in your diet, such as asparagus, peppers, eggplant, cucumbers, cabbage, onions, celery, pumpkin, green-leaf vegetables, legumes such as beans and lentils. Cauliflower and broccoli are allowed in limited amounts. Ideally, vegetables should form the largest food group in your diet; they should cover at least half of the plate. A good example is a large salad with protein meal and dressing. Vegetables to be avoided are the starchy ones, such as potatoes and rice, while corn, carrots, and peas may be eaten sparingly.

Fruits:
Consumed only in limited amounts as they contain a lot of sugar. One can eat fruits that are low to medium in sugar such as green apples, berries, cherries, strawberries, blackberries, tomatoes, grapefruit, lemons and fresh lemon juice, limes and coconut. The fruits which contain the highest quantity of sugar should be avoided and include all dried fruit (for instance, raisins and figs, among others) and tropical fruits, such as bananas, oranges, mangoes and pineapples.

Nuts and Seeds
One can eat raw nuts such as walnuts, cashews, almonds, and pistachios. These provide valuable healthy fats, fibre, magnesium and potassium. Roasted nuts may be baked with hydrogenated oils which are bad trans fats so should be avoided. Avoid peanuts as they can contain large amounts of fungi/moulds and their mycotoxins.

Fats
It is important to satisfy your needs for essential fats like Omega-3 fats by eating fish – salmon and mackerel or by using flax seed oil. Foods with a high amount of monounsaturated fat, such as olive oil, avocado, and nuts, have indisputable health benefits.

I am aware that many would find this type of diet, which is really a lifestyle choice, too restrictive and unable to stick with it long term. Unfortunately many people live in total disregard of themselves which is not self loving. They tend to over indulge in foods they know are not good for them but do so anyway. Ultmately this results in a spleen condition which affects the adrenals, nervous system, etc.

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Phosphatidylcholine (PC) is an essential phospholipid which consists of phosphate, fatty acids and choline. It is essential for life as it makes up about 50% of all cell membranes making it one of the most important molecules in the body. It is also one of the components of bile (it is required for normal transport of bile acids). It also emulsifies and breaks down fat deposits in the body, which make it helpful in the prevention of gallstones, atherosclerosis, heart disease, and liver problems. It makes cholesterol more soluble and less able to cause hardening of the arteries. The choline in phophatidylcholine is necessary for metabolism of fatty acids and for the transport of fats through cells. Without it fat actually becomes trapped in the liver which interferes with liver function. Some researchers have also hypothesized that the ability of phosphatidylcholine to increase levels of acetylcholine in the brain might help people with Alzheimer’s disease, though clinical studies have not supported this theory. Still, people with mild to moderate dementia may benefit from supplements of phosphatidylcholine.
PC is an essential component to the PK protocol developed by Patricia Kane PhD which involves lipid replacement therapy using phospholipids such as PC. PC lipid replacement helps repair the damage to cellular membranes caused by biotoxins which tend to reside in the membrane fatty layer. In addition the PC helps flush the liver and gall bladder to aid the detoxification process of the biotoxins. This protocol is used for conditions such as chronic fatigue, fibromyalgia, Lymes disease, MS and multiple chemical sensitivities.
PC is also an essential component for Mesotherapy which is a non-surgical cosmetic medicine treatment which employs multiple injections of pharmaceutical, vitamins and nutraceuticals, including PC, into the subcutaneous fat to help dissolve it for weight loss.
Phosphatidylcholine is commonly available as a supplement obtained from lecithin which usually contains anywhere from 10% to 35% PC. These tend to be ineffective as the lecithin is unable to form a micelle when taken orally and thus are digested by lipase, phospholipase and other enzymes in the gut which break the PC down into its individual components before being absorbed.

If however highly purified PC (95 to 98%) is used it encourages the formation of PC micelles/liposomes when exposed to the watery environment in the gut. These tiny micelle spheres then transverse the gut wall and thus are absorbed without being broken down by digestive enzymes. These micelles/liposomes are being utilised by the pharmaceutical industry to increase the absorption of certain drugs captured inside the liposome sphere due to their high absorption rates.
The recommended dosage of a oral supplement that contains 95% phosphatidylcholine is 350 -500 mg three times per day for liver disorders, 500-900 mg three times per day to lower cholesterol, and 2 to 5g daily for lipid replacement therapy to rebuild cell membranes and flush the liver.
PC is also available as an injection at 100mg/ml for mesotherapy or for the PK protocol.
There have been few side effects reported with the use of phosphatidylcholine supplements other than gastrointestinal upset when large doses are used. High doses in the form of lecithin may cause a decrease in appetite as well.
Our laboratory produces both an oral liquid and injectable forms of PC using a highly purified source of PC thus ensuring it is effective. The oral liquid contains 100mg/ml  – Click here to order.

Our lab also produces choline capsules. These conatin 300mg choline as choline bitartrate which are better absorbed than many other choline forms. Click here to order.

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Chrysin (5,7-dihydroxyflavone) is a naturally occurring bioflavonoid extracted from the plant Passiflora coerulea. In the early 1980’s it was found to have the ability to inhibit the conversion of testosterone into estrogens by inhibiting the enzyme called aromatase. Aromatase inhibiting drugs (Arimidex) have been traditionally used to treat women with estrogen dependant breast cancers, as estrogens are produced in fat cells via these enzymes in a process called aromatisation. The use of these inhibitors are however becoming more popular in aging men seeking to gain control over their sex hormone levels, suppressing excess estrogen production while boosting low testosterone levels to a youthful state.

Declining testosterone in aging males can be the result of several factors one of these being an excess of the aromatase enzyme activity resulting with too much testosterone being aromatised into estrogen. This elevation in estrogen levels then acts on the brain to turn off testosterone production by a negative feedback mechanism resulting in a decline in the testosterone/estrogen ratio. The increased estrogen levels also increase SHBG (sex hormone binding globulin) levels which then binds to whatever free testosterone is left thus further reducing its free and active form levels even further. This cascade effect causes a hormone imbalance between estrogen and testosterone and is suspected to be involved in the formation of prostate problems as well as the many symptoms such as : decreased libido, erectile dysfunction, ejaculatory problems, decreased energy and strength, increase in body fat, loss of muscle mass, prostate enlargement, osteoporosis, depression, inability to concentrate, reduced mental agility and loss of enthusiasm.

In these cases where an excess of aromatisation exists the use of an aromatase inhibitor can help obtain a healthy estrogen:testosterone balance.  This can result with an increase in strength and stamina, increase in energy levels, improved muscle tone, increased libido, improved sexual function, improved mood and mental agility and a greater zest for life.  However in cases where low testosterone levels are not related to excessive aromatisation the use of aromatase inhibitors on their own are of little benefit. Therefore testing is essential to ensure its use is suitable.

Diagnosis

If you suffer from any of the symptoms listed above then it is a good idea to have your testosterone, DHT, estrone and estradiol hormone levels tested.

If test results indicate that estrone/estradiol is high and testosterone is low then chrysin therapy should be initiated to rectify the imbalance. Chrysin should also be used in men currently on testosterone replacement which follow up test results indicate that they are converting too much of it into estradiol.

Administration

Early research using oral chrysin has found it not to be as effective at enhancing testosterone levels as was anticipated. The problem was later found to be due to its poor absorption into the blood stream after oral administration. When taken orally large doses of 1 to 3g are required in order for enough to be absorbed to be effective. Pilot studies using it in combination with piperine found that after 30 days serum estradiol levels were reduced and free testosterone levels were increased which suggests that absorption was improved with the addition of piperine, however large doses were still required.

It has been reported that chrysin creams are effective at one tenth the oral dose, that is 100 to 300mg daily. Therefore creams appear to be the preferred method of administration. The benefit of using a cream base is that chrysin may be dissolved into the cream base along with penetration enhancers making it absorb through the skin much easier, whereas when taken orally this water insoluble flavonoid is only minimally absorbed. Creams also bypass the stomach and liver thus minimising gastric degradation and first pass metabolism thus allowing smaller doses to be administered. The quality of the chrysin cream is however paramount for its effectiveness. Many creams available are grainy in texture which indicates that it is not adequately dissolved in the cream base and thus will not be effectively absorbed through the skin leaving the grainy chrysin crystals on the surface of the skin.

The best way to supplement chrysin is to start with applying 1g of a good quality 10% Chrysin cream daily. This equates to a total daily dose of 100mg. After using the cream for approximately six to eight weeks a follow up hormone test should be performed to evaluate if estrogen levels are decreasing and if they are not then an increase in dose is required. This will involve the use of a 10% Chrysin cream twice to three times a day. If three times a day dosing on 10% cream does not work then it is time to switch to Arimidex.

Chrysin is available from us. Contact us for details.

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Iron is an important dietary mineral that is involved in various bodily functions, including the transport of oxygen in the blood. This is essential in providing energy for daily life. Iron deficiency means less oxygen is delivered to the cells. This can lead to fatigue, tiredness and decreased immunity. Other symptoms may include: hair loss, irritability, weakness, brittle or grooved nails, atrophy of the mucous membrane covering the tongue, the pharynx and the oesophagus, and impaired immune function

Iron deficiency is a common health problem
Iron deficiency is a common problem. High-risk groups include menstruating women, pregnant women, babies and toddlers, teenage girls and female athletes. Without intervention, a person whose dietary intake of iron is inadequate to meet their body’s needs will eventually deplete their iron stores and develop iron deficiency anaemia. It is important you have your levels tested if you suspect they are low. Do not self diagnose as these symptoms are common to many other conditions – not just iron deficiency. If you supplement iron unnecessarily you can be causing yourself harm. Iron is a strong oxidising agent and can cause oxidative stress in the body if levels are elevated. We never recommend iron supplements unless it has been tested and shown to be deficient.

Causes of iron deficiency
Some of the common causes of iron deficiency in adults include:

• Inadequate dietary intake – the two types of iron include haem iron (found in animal foods) and non-haem iron (from plant products). The body absorbs haem iron much more easily than non-haem iron. There are many reasons why the dietary intake of iron could be inadequate, including a poorly balanced vegetarian diet, chronic fad dieting or limited access to a wide range of fresh foods – for example, as a result of living in remote areas or having a low income.
• Blood loss – iron deficiency easily occurs in situations of blood loss such as heavy menstrual periods, regular blood donation, chronic disorders that involve bleeding (such as peptic ulcers, polyps or cancers in the large intestine) and certain medications, particularly aspirin.
• Increased need – the adolescent growth spurt, pregnancy and breastfeeding are situations when the body requires more iron. If this increased need isn’t met, a deficiency can quickly occur.
• Exercise – athletes are prone to iron deficiency because regular exercise increases the body’s need for iron in a number of ways; for example, hard training promotes red blood cell production, while iron is lost through sweating.
• Inability to absorb iron – healthy adults absorb about 10 to 15 per cent of dietary iron but some people’s bodies are unable to absorb or use iron from food.

Diagnosis

Ask your doctor to test for iron. Testing for Ferritin is the most sensitive index of early iron deficiency. We recommend your ferritin level, as a minimum, should be above 90 despite the fact that most pathology labs report a so called normal reference range minimum to be around 30. Recent research suggests this is too low. Most patients feel better when higher levels around 90 to 100 are achieved.
Iron-rich foods
Good sources of dietary iron include red meat, fish, poultry, lentils, beans, leaf vegetables, tofu, chickpeas and black-eyed peas. Lower amounts are also found in molasses.

Iron from different foods is absorbed and processed differently by the body; for instance, iron in meat (heme iron source) is more easily broken down and absorbed than iron in grains and vegetables (”non-heme” iron source).

Iron absorption by the body can be affected by the amount and type of iron consumed, dietary factors that enhance or inhibit iron absorption and an individual’s need for iron (when the body is low in iron, it absorbs a higher percentage from food). Absorption of iron from food is about 18 per cent from a typical western diet (including animal foods) and about 10 per cent from a vegetarian diet.

In many cases we find that ferritin levels do not rise substantially if only on an iron rich diet. Usually supplements are also required in order to achieve reasonable levels.

Iron Supplements

The amount of iron absorbed decreases with increasing doses. For this reason, it is recommended that most people take their prescribed daily iron supplement in two or three equally spaced doses. For adults who are not pregnant we recommend using from 20mg daily twice daily to 20mg three times a day. Each person is different so you need to dose according to individual needs.

The absorption of iron differs depending on the form used. Ferrous sulphate, often prescribed by doctors, is poorly absorbed and thus causes side effects such as constipation. Vitamin C is reported to improve absorption but only marginally. We recommend iron picolinate as it is one of the most highly absorbed forms available and thus rarely causes constipation.

Our laboratory produces 20mg elemental iron capsules in the form of iron picolinate – click here to order. For those who suffer from malabsorption and related conditions where gut absorption is low we also produce a sublingual lozenge to overcome this problem - click here to order. We recommend a 3 month course before being retested to determine if you need to continue with the supplements or not.

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The natural decline in male testosterone production that occurs with aging is attributed to a decline in the production of the pituitary hormone LH (Luteinizing hormone). LH is responsible for the stimulation of the male testes to produce testosterone and sperm. Therefore declining levels of LH causes a decrease in testosterone production,  sperm production and testicular atrophy.

The hormone Human Chorionic Gonadotrophin  (HCG) is prescribed by leading hormone experts for men to stimulate their own natural testosterone production as HCG stimulates the testes in much the same way as LH does. HCG hormone is not a natural male hormone but mimics the natural hormone LH almost identically. As a result HCG stimulates the leydig cells of the testes, in the same manner as LH, increasing testosterone production. The treatment objective of HCG is to stimulate the male testes to naturally produce more testosterone and thus overcome any deficiency without the need of using testosterone itself.

It may also be used by men on testosterone therapy in order to overcome side effects. Some men suffer from the body’s natural negative-feedback mechanism which causes the body to shut down its own production of testosterone via the hypothalamic-pituitary-gonadal axis. This causes testicular atrophy, among other things. HCG is also now being used more commonly in these cases to maintain and restore testicular size as well as normal testosterone production.

HCG had previously only been available as an intramuscular injection which deterred men from using it as it can be too inconvenient. Our laboratory has developed a nasal spray which delivers pharmaceutical grade HCG into the body without the need for injections. Therefore HCG can now be easily administered daily using nasal spray technology. If your doctor is interested in prescribing HCG Nasal Spary for you have them contact us for details.

HCG has also been used as part of a controversial weight loss program.

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People with irritable bowel syndrome (IBS) may suffer from constipation, diarrhoea (sometimes one alternating with the other), abdominal aches and pains, abdominal bloating, and/or flatulence. In chronic cases these gut symptoms can eventually cause other major health problems such as fatigue, depression, malabsorption syndrome, nutritional deficiencies, etc.

Causes of IBS
The underlying cause of IBS is still unknown, but certain factors have been found to ‘trigger’ attacks in susceptible individuals. These include:

Infection – Many of our IBS patients have found to have either a bacterial, parasitic or yeast infection in the bowel that may be contributing towards their symptoms. Parasites such as Blastocystis, Dientamoeba fragilis and cryptosporidium, yeasts such as candida and pathogenic bacteria such as clostridium are all too common in IBS patients we see.

Food intolerance – any food allergy or intolerance may contribute towards IBS symptoms. Generally the most common problem foods are dairy, gluten and yeast however you could potentially be intolerant to just about anything in your diet even foods you may consider to be a healthy such as various fruit and/or vegetables. Sugars may also exacerbate IBS symptoms.

Poor Digestion/Absorption – In some IBS cases we find a deficiency in pancreatic enzymes which are responsible for the appropriate digestion of the foods you eat. If not digested properly due to pancreatic deficiency the food remains in your bowel and feeds opportunistic bacteria resulting in fermentation which can contribute towards your IBS symptoms.

Bacterial Flora Imbalances (Dysbiosis) – many IBS patients we see are found to have inadequate numbers of beneficial bacteria in their bowels which are responsible for a balanced immune system and also aid digestion.

Emotional Issues – strong emotions, such as anxiety or stress, can affect the nerves of the bowel in susceptible people and cause IBS symptoms. In addition many suffers tend to bury their undelt with emotions which usually involve not accepting life into their bowels thus causing IBS symptoms.

Medications – certain drugs (such as antibiotics, antacids and painkillers) can lead to constipation or diarrhoea.

Testing for the Causes of IBS

Firstly IBS needs to be distinguished from other conditions with similar symptoms such as inflammatory bowl disease, polyps, and diverticular disease. Once these have been ruled out there are no specific tests for IBS per say however we find the two most important tests to help determine what is the most appropriate treatment include:

(1) Complete Digestive Stool Analysis (CDSA) - this test will be able to determine the balance of beneficial bacterial flora in your gut, Check for the presence of any pathogens, access pancreatic function and digestion as a whole, checks for absorption markers, diagnose gluten allergies, to name a few. This is very important information to determine how to balance and repair gut function.

(2) ALCAT Food Allergy Blood tests – this test will be able to detect any food allergies and/or intolerances in order to be able to tailor make a specific diet avoiding any problematic foods that may be contributing towards IBS symptoms. NB: Standard food allergy tests will only detect food allergies and not food intolerances so will not provide a complete picture on all the foods you should avoid.

Two other tests that may be useful in certain situations include:

(3) Heavy Metal 24hr Urine test with chelating agent challenge – this test has been included for some patients who appear to have a heavy metal issues which is known to damage the mucosa of the gut wall lining and thus produce IBS type symptoms.

(4) Gut permeability urine test – IBS has been associated with increased gut permeability (leaky gut syndrome) and low grade inflammation. This test may help identify the extent of damage and act as a baseline to monitor the effectiveness of your treatment.

All these tests may be orgnised during a consultation with Dr Serafin.

Treating IBS

The treatment should be based on the test results and may include:

(1) Probiotics – to help re-establish a healthy balance of appropriate gut flora. We routinely recommend ultrabiotic 45 made by Bioiceuticals which provides high doses of all the appropriate bacterial strains to colonise the small and large intestines which aid digestion and your immune system. Click here to order

(2) Digestive Enzymes – used to aid digestion if found to be diminished. We recommend using multigest enzymes made by Bioceuticals which is a balanced formula used for protein, fat and carbohydrate digestion. Click here to order.

(3) Repair Leaky Gut – If leaky gut is suspected or diagnosed by a gut permeability test then we recommend using Intestamine made by Bioceuticals which contains high doses of glutamine, slippery elm, aloe vera and a host of other nutrients specifically formulated to treat leaky gut. Click here to order.

(4) Eradicate any pathogen found – this step involves using the appropriate treatment to eradicate any candida, parasite or pathogenic bacteria found in your bowel. This step is essential for a complete recovery.  For information on treating candida click here. Information on treating parasites and bacteria will be given during a consultation based on the results of sensitivity studies.

(5) Diet – avoid any foods identified as being problematic by the ALCAT blood test. Increase fibre in the diet.

(6) Remove Heavy Metals – if found to be present you should act to remove any heavy metals by using either some form of chelation therapy such as DMSA or zeolites. Click here for more information.

(7) Esoteric Healing – energetically bowel problems are due to burying emotional issues and not dealing with them appropriately. Trying to manage the symptoms of this condition without dealing with these issues will only bury them deeper. We recommend esoteric healing to facilitate the process of letting them go and thus being healed. Click here for more information.

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Unfortunately many mainstream medical doctors refuse to prescribe bioidentical hormones as they are considered unorthodox treatments and instead prefer to continue to prescribe traditional synthetic and horse urine derived hormones despite the evidence. Some so called hormone “experts” even argue that there has not been any research on bioidentical hormones and they have no proven improved safety or efficacay compared to what is already being used. This is most definitely misleading and incorrect information in two ways. Firstly this type of statement assumes that conventional hormones have undergone large trials demonstrating they are safe and effective and that they should be the standard benchmark to which bioidenticals should be compared to when in fact there has never been a large controlled trial of traditional hormone replacement therapies. We should not establish a benchmark treatment to which all others should be compared if that benchmark has not been fully tested itself! Secondly there have indeed been a number of clinical studies over the years proving the safety and efficacy of bioidentical hormones and the evidence is continually growing.

Estriol, estradiol, estrone, progesterone and testosterone have all been individually approved for human use by the Therapeutics Goods Administration (TGA) in Australia and have been scheduled on the SUSDP. In addition all these hormones have been approved and listed in both the US and British Pharmacopoiea’s which are considered to be the medical industries bible. In addition hormones such as progesterone cream and DHEA are considered so safe in many other countries around the world that they are classed as a supplement and therefore available over the counter through health food stores and pharmacies while here in Australia they are only available on prescription.

A lot of confusion lies with the fact that in Australia no bioidentical hormone combination has been registered for commercial supply and therefore listed on the ARTG, even though several individual bioidentical hormones have. Single ingredient bioidentical estriol, estradiol and testosterone have all been registered and are commercially available and often prescribed as single ingredient preparations. The problem occurs when hormone combinations are required because these hormone combinations have not been registered on the commercial ARTG list. Not being listed does not mean they have not been approved for human use and are therefore unsafe. The truth is that being natural hormones pharmaceutical companies legally cannot patent these hormones. If they can not patent these hormones they do not develop these combinations and have them registered with the TGA as they deem them unprofitable. If the pharmaceutical companies do not pay to have these hormone combinations registered then the TGA will not register them. In the end the patient suffers because the companies will not make enough money from it.

In addition there are several so called experts whom are publically outspoken about the erroneous dangers of bioidentical hormones and promote the use of traditional HRT combinations such as conjugated estrogens with medroxyprogesterone which have been used or the  last 30 years or so without any large scale trials indicating any significant benefit and continues to be recommended even though recent large observational trials indicate considerable risk. These doctors have strong links and are financed by the pharmaceutical company whom produce these products and thus their motives for presenting much misinformation needs to be questioned?

Finally seminars that many doctor’s attend for their continuing education hosted by a certain organisation includes a poorly designed study which indicated progesterone cream was unable to effectively treat hot flushes, night sweats and other menopausal symptoms in order to teach doctors that bioidentical hormones do not work. This study also found that there was no increase in progesterone serum levels while on the progesterone cream thus teaching the doctors that the creams do not absorb. Two major problems with this study were that firstly menopausal symptoms are the result of low estrogens so why was progesterone used in this study and not a bioidentical estrogen which would normally have been used in a clinical situation? Secondly it has been proven that transdermal progesterone will not appear in serum tests due to limitations with the testing proceedure but does so in saliva tests within an hour after applying the dose. So why were serum tests used and not saliva? Was the test designed to fail from the start or was it innocent ignorance? Unfortunately when doctors are presented with this erroneous information they assume that it is correct and walk away thinking these hormones do not work. If your doctor tells you that you can bathe in progsterone cream and not absorb any of it you will know they have attended one of these seminars!

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Topical anesthesia is needed for common procedures such as suturing, wound cleaning, injection administration, cosmetic and laser procedures, tattooing, etc. The ideal topical anesthetic would provide complete anesthesia following a simple pain-free application, not contain narcotics or controlled substances, and be safe to use.

One of the most common local anesthetics produced by our laboratory include a combination of the topical anesthetics lidocaine and tetracaine in addition to epinephrine which is a vasoconstrictor. This gel is known as LET Anesthetic Gel. It has been used to treat pain associated with lacerations and for cosmetic procedures where the skin may be broken such as cosmetic or regular tattooing. The vasoconstrictor helps control swelling and bleeding. The onset of action is usually 20 to 30 minutes after being applied.

A triple-anesthetic gel containing benzocaine, lidocaine, and tetracaine (BLT Gel) has also been reported to be effective when applied prior to laser and cosmetic procedures. Convenience of application without need for occlusion is an advantage of this topical anesthetic gel in addition to a rapid onset of action of 20 to 30 minutes compared to 1 to 2 hours often observed with EMLA cream. The following article reported that a triple-anesthetic gel containing benzocaine, lidocaine, and tetracaine (”BLT”) applied prior to treatment with a 532-nm KTP laser resulted in significantly lower pain scores than with 3 other topical anesthetics at 15, 30, 45, and 60 minutes after application.

Cosmetic Dermatology 2003 Apr;16(4):35-7
Topical Triple-Anesthetic Gel Compared With 3 Topical Anesthetics
Lee MWC
Department of Dermatologic Surgery, University of California, San Francisco.

Finally our lab also produces a lidocaine and prilocaine combination (similar to EMLA) however LET and BLT gels are generally considered superior due to a more rapid onset of action and they do not require occlusion.

We supply an over the counter range for cosmetic and regular tattoo artists and a stronger prescription range for cosmetic laser clinics. Contact us for further information and for our competitive prices – you will be surprised how much you can save.

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Alprostadil 20mcg/ml
BIMIX – alprostadil and phentolamine combinations of varying strengths
TRIMIX – alprostadil, phentolamine and papaverine combinations of varying strengths
QUADMIX – alprostadil, phentolamine, papaverine and atropine combinations of varying strengths.

These injections produce less pain, are more affordable and more potent when compared to standard therapy and are recommended by most ED specialists. There are 12 different injection combinations in our complete range in order to cover the wide range of needs observed within the male population. We courier these injections Australia wide via overnight courier packed in ice. Contact us for more information.

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It is now well recognized that obesity can increase the risks of diabetes, cardiovascular disease, certain cancers, gout, osteoarthritis and gall bladder disease. Many people find it very difficult to lose weight even though they exercise, eat right and having had tried every diet pill on the market. This is because most treatments do not address the underlying cause of excess weight. Quite often a number of chemical imbalances are present that makes you gain weight and prevents you from losing weight. One such imbalance was first described by Professor Gerald Reaven in 1988 which he called Syndrome X but is now commonly referred to as metabolic syndrome.

Metabolic Syndrome is characterised by:

(1) Insulin resistance – the body is resistant to the effects of insulin as it is unable to transfer glucose from the blood stream into cells very efficiently. The glucose that does not enter cells is then transferred into fat deposits making you fatter.

(2) High hormone Insulin levels – the pancreas has to secrete more insulin to make up for the lack of sensitivity.

(3) Abnormal blood fats – High insulin levels cause increased triglycerides, decreases HDL’s (good) and increases LDL (bad) cholesterol.

(4) Blood glucose abnormalities – Blood glucose levels are unstable and can swing from too low to too high.

(5) Sex, adrenal and thyroid hormone imbalances – estrogen dominance,  adrenal exhaustion and/or hypothyroidism can cause weight gain and make it very difficult to lose weight.

Diagnosis Of Metabolic Syndrome:

(1) Fasting level of blood fats – Triglycerides, HDL and LDL cholesterol should all be within the normal range.

(2) Fasting Blood Glucose – If your fasting blood glucose is over 6.1mmol/L it is a sign of insulin resistance.

(3) Glucose Tolerance Test – measures the tolerance of an individual for an extra load of administered glucose. If your tolerance for the extra load of glucose is normal then your blood glucose levels will remain within the normal range. If your tolerance is impaired then your glucose levels become higher than the normal range (Normal levels: Fasting 3.6 – 6.1mmol/L;One hour after glucose load < 9mmol/L; TWO hours after glucose load < 7.1mmol/L).

(4) Serum Insulin Levels – Normal insulin levels during a glucose tolerance test should be: Fasting < 1, One hour 9 to 60, 2 hours 5 to 50, Three hours 1 to 24 mU/L.

(5) Liver Function test – Elevated liver enzymes may indicate fatty liver which is common in Syndrome X

(6) Hormone levels – Low progesterone and thyroid hormones as well as high estrogen and cortisol levels can be responsible for weight gain and make it nearly impossible to lose weight. All these need to be tested  – for more information click here.

Treatment for weight loss involves:

(1) Reducing Insulin Levels – involves reducing insulin levels by reducing simple sugars and refined carbohydrate intake by avoiding foods with a high glycemic index such as sugar and white flour which causes an escalation in glucose and insulin levels. Replace refined carbohydrates with quality protein and fresh vegetables - click here for details. Seek some dietary advice or get informed by reading some good books such as “The Zone Diet”.

(2) Increase Insulin Sensitivity – by making insulin work better by taking supplements such as chromium, lipoic acid, vandium, selenium and omega 3 & 6’s essential fatty acids. Our laboratory produces a combination supplement containing 500mcg chromium, 300mg lipoic acid and 5mg vandium for this purpose. Click here to order.

(3) Improve Liver Function – Liver is the major fat burning organ of the body and regulates fat metabolism. It controls carbohydrate metabolism and blood glucose control. A dysfunctional liver can cause a whole range of symptoms from weight gain, irritable bowl syndrome, sugar cravings, depression, foggy thinking, fatigue, excessive sweating, brown spots, recurrent infections, toxic overload. By cleansing the liver you will detoxify it and improved its fat burning functions. A liver cleanse involves using a low reactive diet for 14 days or longer if required. This briefly involves eating vegetable juices and eating raw foods especially salads and vegetables. Limit raw fruits as they are high in sugar and thus increase insulin levels. Stop intake of any dairy, gluten, yeast, caffeine, nicotine, alcohol, meats, etc. Take sulphur containing foods such as cabbage, onions, garlic shallots or supplement with MSM. Use a liver tonic with milk thistle, dandelion, globe artichoke, antioxidants, cysteine, glycine and glutamine which will stimulate phase I and II liver detoxification reactions. We recommend using Metagenics Thermophase Detox to provide all these nutrients and to use it while on this diet. Click here to order.

4) Balance Thyroid Hormones – low levels of thyroid hormones or a thyroid hormone imbalance such as reverse T3 dominance slows down your metabolism and can be the hidden problem that prevents you from losing weight. If you have low thyroid activity you may experience weight gain, fluid retention, bloating, constipation, hair loss, dry skin, low body temperature and fatigue. If you experience any of these symptoms refer to the information on treating Hypothyroidism.

(5) Balance Adrenal Hormones – prolonged periods of stress can initially cause the adrenal glands to produce excessive amounts of cortisol which can cause moon face, weight gain, fluid retention and bloating. This is known as stage 1 adrenal exhaustion. As adrenal exhaustion proceeds a reduction in metabolism ocuurs and thus low energy will result causing further weight gain. Refer to adrenal section for details on how to resolve this issue.

(6) Balance Sex Hormones – Estrogen dominance is a condition where an excess of estrogen is not appropriately balanced with progesterone. This usually occurs somewhere in your late 30’s to early 40’s as a result of perimenopause. This condition promotes weight gain and makes it very difficult to lose weight because estrogen converts calories into fat instead of burning it off. Excess estrogens may also reduce thyroid function creating a further drop in metabolism levels.

(7) Reduce Leptin Resistance – The hormone leptin has been found to be a major regulator of body weight and metabolism. Leptin is secreted by fat cells and the levels of leptin increase with the accumulation of fat. The increased leptin secretion that occurs with increased weight normally feeds-back to the hypothalamus as a signal that there are adequate energy (fat) stores. This stimulates the body to burn fat rather than continue to store excess fat, and stimulates thyroid releasing hormone (TRH) to increase thyroid stimulating hormone (TSH) and thyroid production. Studies suggest that the majority of overweight individuals who are having difficulty losing weight have varying degrees of leptin resistance, where leptin has a diminished ability to affect the hypothalamus and regulate metabolism. This leptin resistance results in the hypothalamus sensing starvation, so multiple mechanisms are activated to increase fat stores, as the body tries to reverse the perceived state of starvation. The mechanisms that are activated include diminished TSH secretion, a suppressed T4 to T3 conversion, an increase in reverse T3, an increase in appetite, an increase in insulin resistance and an inhibition of lipolysis (fat breakdown). The result? Once you are overweight for an extended period of time, it becomes increasingly difficult to lose weight. Most underweight or normal weight individuals will have leptin levels below 10, although most major labs will use a reference range of 1 to 9.5 for men and 4 to 25 for women. (It must be remembered that this range includes 95% of so-called normal people and includes many who are overweight.) There are several treatments available which usually include drugs that control insulin resistance. This may also be achieved through diet and supplements. Leptin resistance may also be the result of inflammation so some form of antiinflammatory may be useful to reduce leptin resistance. Dr. Jeffrey Flier and his colleagues at Harvard Medical School have led these efforts. They have discovered that a group of molecules involved in reducing inflammation also interfere with leptin signaling on the cell surface and inside the cell. These molecules are known as SOCS, which stands for suppressors of cytokine signaling. Two specific SOCS molecules, SOCS-1 and SOCS-3, have been shown in many animal studies, first by Flier’s group and later by other research teams, to jam the signals that leptin is supposed to deliver to brain cells and muscle cells.

Other Treatments Available

HCG stands for Human Chorionic Gonadotropin, a hormone present in both men and women, but which is produced in great amounts in pregnant females.  During pregnancy, the substance almost completely controls the woman’s metabolic functions.  In non-pregnant persons, research suggests hCG similarly increases the metabolism similar to a pregnant female.  Thousands of calories in stored fat are released, and are used by the body or expelled. HCG may be administered by daily injections or more convenient HCG nasal spray.

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