I am excited to announce that Varian Medical Systems has acquired Mobius Medical Systems.

This means wonderful things for our team, our users, and our products. Varian is committed to the future of the Mobius QA products and places a high value on the talent and technology that Mobius Medical Systems has built over the last 7 years.

This acquisition allows Varian to expand its QA portfolio and use the established Mobius QA solutions to improve treatment outcomes on a global scale. Varian will continue to develop the Mobius QA product line as part of their strategy to transform from a radiation therapy company to a broader cancer care company.

On a personal note, I am excited to join with Varian. Working together, we can accomplish so much more than we ever could working alone. I am extremely proud of the Mobius team. We have built innovative products and provided excellent customer support with a small number of highly talented employees. I have seen Varian’s deep appreciation for who we are at Mobius and what we have built. My team and I are thrilled to join Varian in our shared mission to eradicate cancer.

Sincerely,
Nathan Childress, PhD, DABR
Associate Vice President
Varian Medical Systems

Using an in-house collapsed cone convolution/superposition algorithm with over 100 reference beam models, Mobius3D provides users with 3D dosimetry verification, phantomless IMRT QA, and daily treatment QA. More than 300 clinics worldwide have switched to Mobius3D for patient QA, using a mix of 4 manufacturers’ linear accelerators, 13 different multileaf collimators, 10 photon energies, 14 electron energies, and 8 treatment planning systems.

“Our goal has always been to bring physicists faster, smarter QA,” says Nathan Childress, PhD, DABR, Founder of Mobius Medical Systems, LP. “We always knew that meant supporting high patient volumes, and I am thrilled to see the huge numbers of patients verified by our users.”

Some Mobius3D users have verified over 5000 patients with a single server: University Medical Center Groningen in Groningen, Netherlands verified 12000 patients in just 3 years, and Herlev Hospital in Herlev, Denmark also verified over 11000 patients.

Even more clinics are quickly approaching these numbers. Over 40 Mobius3D installations have verified more than 2000 patients since adopting the system, including University of Wisconsin Hospitals and Clinics Authority (3000 patients), Radiotherapiegroep Arnhem (5000 patients), and University of Texas Southwestern Medical Center (4000 patients across two servers).

With over 300,000 patients clinically verified across all installations, Dr. Childress says, “We aren’t stopping now. Even after we reach 1,000,000 patients, Mobius Medical Systems will continue our mission to develop innovative QA software for modern radiation oncology.”

“Our mission has always been to simplify and streamline machine QA,” said Dr. Nathan Childress, founder of Mobius Medical Systems. “Incorporating TG-148 into DoseLab offers TomoTherapy users the same quick, accurate, and detailed machine QA results that so many others have come to rely on for TG-142.”

About DoseLab
DoseLab is the leading machine QA software solution, with active installations in nearly 1000 centers worldwide. Operating with sub-pixel accuracy, DoseLab provides zero-click machine QA analysis with its
AutoQA module and is the only TG-142 software solution to offer built-in templates for daily, monthly, and annual mechanical checks.

About Mobius Medical Systems
Mobius Medical Systems, LP, offers innovative and powerful software solutions for quality assurance in radiation oncology. Mobius Medical Systems develops both DoseLab and Mobius3D, which provide clinicians worldwide with the important data they need to ensure the safe, efficient treatments.

Mobius3D version 2.0.1 includes new integration of the company’s DoseLab machine QA software and will be available for demonstrations at booth #4029. Clinicians now have the ability to view all of their patient QA and machine QA data in the same user friendly web interface. Version 2.0.1 also showcases the clinically released CBCT module, the first of its kind online tool for patient positioning QA and patient anatomy verification.

“We strongly believe that the process of Machine QA and Patient QA should be separated, but having access to the results in a single interface offers greater efficiency”, remarked Nathan Childress, Ph.D., founder of Mobius Medical Systems. “We were the first company to offer an integrated solution for plan QA, pre-treatment patient specific QA, and in-vivo per fraction QA. With the addition of patient positioning, anatomy verification, and machine QA, there isn’t a more integrated QA system available in our market today.”

The CBCT module is the first of its kind online tool for evaluating patient positioning and patient anatomy changes. Within 60 seconds of performing a cone-beam CT of the patient and performing recommended shifts Mobius3D reports a quantitative density gamma metric. Clinicians can use this metric to decide whether to proceed to treatment or not. The module can reveal incorrect shifts, changes in patient anatomy such as weight loss or even incorrect bolus placement. Once patient position is verified Mobius3D then calculates in vivo 3D dose for each treatment by using the measured log file data from the accelerator.

Neal Miller, Director of Marketing for Mobius Medical Systems stated, “With the addition of this module, we close the QA loop by including the patient in the equation. Mobius3D can provide unprecedented safety and accuracy for patient treatments by verifying plan quality, delivery precision and now patient positioning and anatomy changes too, all while bringing more efficiency to the department through automation.”

The company has partnered with RT-IDea, a Dutch leader in workflow optimization whose management team has extensive distribution experience in the worldwide radiation therapy marketplace. Centralizing sales and support functions in the Netherlands will allow the new organization to provide the high level of service that Mobius Medical Systems is known for to the whole of EMEA. The new office will be responsible for all aspects of software and hardware support for existing users in the region and will also facilitate installations and training for new customers.

Nathan Childress, Founder of Mobius Medical Systems stated, “While we have done a good job supporting our current base of customers in the region, we are experiencing quickly growing demand for our products, especially the upcoming CBCT module for online patient positioning verification in Mobius3D. We felt it was time to expand our company footprint. We are very excited to work with RT-IDea to advance our efforts in bringing the best QA solutions to more customers in the EMEA market.”

“We believe that Mobius is truly changing Patient and Machine QA in Radiation therapy.”, says Joos Wisse, Managing Director for RT-IDea, to which his business partner, Patrick Hylkema added, “Mobius Medical Systems’ innovative and intuitive software solutions relieve the clinical concerns that come from greater treatment complexity and a continuously increasing workload by fully automating patient and machine QA.”

The group reported that in a one-year period ending in 2015 Mobius3D was used to assess the quality of over 3,500 patient plans. The system also performed pre-treatment, patient-specific verification of those plans, while also continuously monitoring individual fractions to confirm the safety and accuracy of each delivery. Within one year’s time, Mobius3D had verified a remarkable total of over 56,000 patient fractions in this clinic alone.

Sune Kristian Buhl, one of Herlev’s medical physicists stated, “Not only is Mobius3D more time-efficient than our former methods, all verifications are done on the actual patient anatomy. This increases our trust in the data and provides more confidence in the safety and accuracy of the treatments that our patients are receiving.”

Nathan Childress Ph.D., founder of Mobius Medical Systems said, “We developed our log file based QA system, Mobius3D, to provide clinicians with a more efficient and more accurate way to perform patient specific quality assurance. We are pleased to have the ACR confirm that using log files qualifies as an alternative IMRT/VMAT QA method.”

Mobius Medical System’s Mobius3D software is the only commercially available system utilizing measured log files to perform patient specific end-to-end testing. Mobius3D uses the measured data from log files and a proprietary collapsed-cone convolution-superposition algorithm to determine three-dimensional dose to the patient. The process is completely automated and requires only the time needed to deliver the treatment fields.

Since its formation, Mobius has been providing the radiation oncology community with innovative software to streamline QA processes and increase positive patient outcomes. Over 1,000 clinics worldwide choose to use a variety of products from Mobius. While DoseLab led the way as its breakthrough product, rapidly becoming the most widely used TG-142 software solution, its success was followed by the release of additional cutting-edge products: Mobius 3D and Mobius FX, the first 3D patient plan and patient delivery QA system.

“It has been an amazing five years,” said founder, Dr. Nathan Childress. “Our team has grown from a team of one to nearly 30 people. We started selling a single product (DoseLab) and now have expanded to a diverse line of six hardware and software products. I’m honored to help guide the most advanced team in radiation oncology development to optimize patient care. We know that our work has literally saved lives. This remains the focus driving all our future endeavors. With this shared vision, I can’t wait to see what we can achieve in the next five years.”

Nathan Childress Ph.D., founder of Mobius Medical Systems said, “The purpose of creating Mobius3D was to ensure patients receiving radiation would get safe and effective treatments. With the release of version 1.5, clinicians can gain confidence that every fraction is delivered as expected. I am extremely proud of our team for building a product that moves the industry forward by significantly advancing automated radiation oncology QA tools.”

Version 1.5 also adds support for the new Mobius Verification Phantom (MVP). The MVP contains seven ion chamber measurement points and a film plane. Its geometry is built into Mobius3D, allowing QA plans measured using the MVP to be automatically calculated and verified in Mobius3D. The MVP adds flexibility in the Mobius3D ecosystem for commissioning, spot checks, easy investigation into QA failures, and as a secondary IMRT QA device.