display Latest news from The Rockefeller University Press on Newswise en-us Copyright 2026 Newswise 115 31 https://www.newswise.com/ https://www.newswise.com/images/newswise-logo-rss.gif https://www.newswise.com/articles/researchers-identify-new-way-to-inhibit-immune-cells-that-drive-allergic-asthma/?sc=rsin https://www.newswise.com/articles/researchers-identify-new-way-to-inhibit-immune-cells-that-drive-allergic-asthma/?sc=rsin Tue, 26 Mar 2024 10:00:00 EST Researchers at the Keck School of Medicine, University of Southern California, have discovered that a protein called Piezo1 prevents a type of immune cell in the lung from becoming hyperactivated by allergens. The Rockefeller University Press https://www.newswise.com/articles/newly-identified-yeast-could-prevent-fungal-infections-by-outcompeting-rivals-study-suggests/?sc=rsin https://www.newswise.com/articles/newly-identified-yeast-could-prevent-fungal-infections-by-outcompeting-rivals-study-suggests/?sc=rsin Mon, 18 Mar 2024 10:00:00 EST Researchers at the Weizmann Institute of Science in Israel have identified a yeast that could be used to prevent invasive candidiasis, a major cause of death in hospitalized and immunocompromised patients. The study, to be published March 18 in the Journal of Experimental Medicine (JEM), shows that the novel yeast lives harmlessly in the intestines of mice and humans and can displace the yeast responsible for candidiasis, Candida albicans. The Rockefeller University Press https://www.newswise.com/articles/study-identifies-new-pathway-to-suppressing-autoimmunity/?sc=rsin https://www.newswise.com/articles/study-identifies-new-pathway-to-suppressing-autoimmunity/?sc=rsin Fri, 29 Sep 2023 10:00:00 EST Researchers at Stanford University School of Medicine, Yale University School of Medicine, and the Hospital for Special Surgery Research Institute have uncovered new details about how the immune system prevents the production of antibodies that can recognize and damage the body's own, healthy tissues. The study, to be published September 29 in the Journal of Experimental Medicine (JEM), also reveals how this process is impaired in autoimmune disorders such as systemic sclerosis and systemic lupus erythematosus and suggests potential new strategies to treat these diseases. The Rockefeller University Press https://www.newswise.com/articles/mutations-in-blood-stem-cells-can-exacerbate-colon-cancer/?sc=rsin https://www.newswise.com/articles/mutations-in-blood-stem-cells-can-exacerbate-colon-cancer/?sc=rsin Thu, 24 Aug 2023 10:00:00 EST Researchers at the University of Florida College of Medicine have discovered how common age-related changes in the blood system can make certain colon cancers grow faster. The Rockefeller University Press https://www.newswise.com/articles/study-reveals-that-bats-experience-hearing-loss-in-old-age/?sc=rsin https://www.newswise.com/articles/study-reveals-that-bats-experience-hearing-loss-in-old-age/?sc=rsin Thu, 30 Mar 2023 10:15:20 EST Many mammals suffer hearing loss in old age, but bats were thought to be immune to this phenomenon because of the importance of hearing for echolocation. However, researchers in Israel have discovered that bats lose their hearing in old age just like humans do. The Rockefeller University Press https://www.newswise.com/articles/new-gene-editing-technique-reverses-vision-loss-in-mice/?sc=rsin https://www.newswise.com/articles/new-gene-editing-technique-reverses-vision-loss-in-mice/?sc=rsin Fri, 17 Mar 2023 10:00:00 EST Researchers in China have successfully restored the vision of mice with retinitis pigmentosa, one of the major causes of blindness in humans. The study, to be published March 17 in the Journal of Experimental Medicine, uses a new, highly versatile form of CRISPR-based genome editing with the potential to correct a wide variety of disease-causing genetic mutations. The Rockefeller University Press https://www.newswise.com/articles/新的基因编辑技术成功地逆转小鼠的视力损失/?sc=rsin https://www.newswise.com/articles/新的基因编辑技术成功地逆转小鼠的视力损失/?sc=rsin Fri, 17 Mar 2023 10:00:00 EST 视网膜色素变性症是人类失明的主要原因之一。中国的研究人员成功地恢复了患有视网膜色素变性症的小鼠的视力。该研究将于[三月十七日]发表在《实验医学杂志》上。该研究使用一种新型的、高度通用的CRISPR基因组编辑技术，有潜力纠正各种导致疾病的遗传突变。 The Rockefeller University Press https://www.newswise.com/articles/mouse-study-suggests-new-therapeutic-strategy-to-reduce-cardiovascular-disease-in-cancer-survivors/?sc=rsin https://www.newswise.com/articles/mouse-study-suggests-new-therapeutic-strategy-to-reduce-cardiovascular-disease-in-cancer-survivors/?sc=rsin Mon, 19 Dec 2022 10:20:24 EST Researchers at Memorial Sloan Kettering Cancer Center (MSKCC) in New York have discovered that common cancer treatments, such as radiotherapy or anthracycline drugs, cause long-term damage to heart tissue by activating a key inflammatory signaling pathway. The study, published December 19 in the Journal of Experimental Medicine (JEM), suggests that inhibiting this pathway could reduce the chances of cancer survivors suffering heart disease later in life. The Rockefeller University Press https://www.newswise.com/articles/severe-covid-19-caused-by-senile-interferon-response-in-older-patients-researchers-suggest/?sc=rsin https://www.newswise.com/articles/severe-covid-19-caused-by-senile-interferon-response-in-older-patients-researchers-suggest/?sc=rsin Wed, 21 Sep 2022 10:35:44 EST Researchers in Germany have discovered that age-dependent impairments in antiviral interferon proteins underlie the increased susceptibility of older patients to severe COVID-19. The study, published today in the Journal of Experimental Medicine (JEM), shows that aged mice infected with SARS-CoV-2 are protected from severe disease by treatment with one of these interferons, IFN-γ. The Rockefeller University Press https://www.newswise.com/articles/anti-sedative-could-alleviate-cancer-therapy-side-effects-study-suggests/?sc=rsin https://www.newswise.com/articles/anti-sedative-could-alleviate-cancer-therapy-side-effects-study-suggests/?sc=rsin Tue, 20 Sep 2022 11:05:46 EST Researchers in China have discovered that inhibiting a protein called the GABAA receptor can protect intestinal stem cells from the toxic effects of chemotherapy and radiotherapy. The study, published September 20 in the Journal of Experimental Medicine (JEM), suggests that the FDA-approved anti-sedative flumazenil, which targets GABAA receptors, could alleviate some of the common gastrointestinal side effects, such as diarrhea and vomiting, induced by many cancer treatments. The Rockefeller University Press https://www.newswise.com/articles/boosting-neuron-formation-restores-memory-in-mice-with-alzheimer-s-disease/?sc=rsin https://www.newswise.com/articles/boosting-neuron-formation-restores-memory-in-mice-with-alzheimer-s-disease/?sc=rsin Fri, 19 Aug 2022 10:00:00 EST Researchers at the University of Illinois Chicago have discovered that increasing the production of new neurons in mice with Alzheimer's disease (AD) rescues the animals' memory defects. The study, to be published August 19 in the Journal of Experimental Medicine (JEM), shows that new neurons can incorporate into the neural circuits that store memories and restore their normal function, suggesting that boosting neuron production could be a viable strategy to treat AD patients. The Rockefeller University Press https://www.newswise.com/articles/stanford-cancer-team-halts-growth-of-multiple-myeloma-and-diffuse-large-b-cell-lymphoma-in-mice-with-custom-molecule-sbcma-fc-v3/?sc=rsin https://www.newswise.com/articles/stanford-cancer-team-halts-growth-of-multiple-myeloma-and-diffuse-large-b-cell-lymphoma-in-mice-with-custom-molecule-sbcma-fc-v3/?sc=rsin Tue, 26 Jul 2022 10:00:00 EST Researchers at Stanford University have developed "decoy receptor" molecules that inhibit the growth of both multiple myeloma (MM) and diffuse large B cell lymphoma (DLBCL) in mice. The molecules, described in a study to be published July 26 in the Journal of Experimental Medicine (JEM), were also found to be nontoxic in monkeys, suggesting they could be used to treat humans with either of these deadly diseases, which are two of the most common blood cancers around the world. The Rockefeller University Press https://www.newswise.com/articles/broadly-neutralizing-antibodies-could-provide-immunity-against-sars-cov-2-variants/?sc=rsin https://www.newswise.com/articles/broadly-neutralizing-antibodies-could-provide-immunity-against-sars-cov-2-variants/?sc=rsin Wed, 15 Jun 2022 14:20:04 EST Two broadly neutralizing antibodies show great promise to provide long-acting immunity against COVID-19 in immunocompromised populations according to a paper published June 15 in the Journal of Experimental Medicine (JEM). The antibodies were effective against all SARS-CoV-2 variants of concern tested and could be used alone or in an antibody cocktail to diminish the risk of infection. The Rockefeller University Press https://www.newswise.com/articles/discovery-of-an-eat-me-signal-involved-in-synaptic-pruning-and-maturation-of-new-neurons-in-the-adult-brain/?sc=rsin https://www.newswise.com/articles/discovery-of-an-eat-me-signal-involved-in-synaptic-pruning-and-maturation-of-new-neurons-in-the-adult-brain/?sc=rsin Thu, 17 Mar 2022 10:00:00 EST A research group led by Kazunobu Sawamoto, a professor at Nagoya City University and National Institute for Physiological Sciences, and Chihiro Kurematsu, a student at Nagoya City University School of Medicine, has elucidated the mechanism that controls synaptic pruning of new neurons in the adult brain. These findings are expected to be useful in the study of neurological diseases with abnormalities in microglia and synapses, such as autism spectrum disorders (ASDs). The Rockefeller University Press https://www.newswise.com/articles/cancer-cells-iron-addiction-may-enable-specific-drug-targeting-study-suggests/?sc=rsin https://www.newswise.com/articles/cancer-cells-iron-addiction-may-enable-specific-drug-targeting-study-suggests/?sc=rsin Wed, 09 Mar 2022 10:00:00 EST Researchers at the University of California, San Francisco (UCSF), have discovered that cells carrying the most common mutation found in human cancer accumulate large amounts of ferrous iron and that this "ferroaddiction" can be exploited to specifically deliver powerful anticancer drugs without harming normal, healthy cells. The therapeutic strategy, described in a study to be published March 9 in the Journal of Experimental Medicine (JEM), could be used to treat a wide variety of cancers driven by mutations in the KRAS gene. The Rockefeller University Press https://www.newswise.com/articles/cancer-drug-shows-promise-in-treating-infants-with-rare-disease-that-causes-tissue-overgrowth/?sc=rsin https://www.newswise.com/articles/cancer-drug-shows-promise-in-treating-infants-with-rare-disease-that-causes-tissue-overgrowth/?sc=rsin Wed, 26 Jan 2022 10:00:00 EST PIK3CA-related overgrowth spectrum (PROS) is a group of rare, incurable disorders caused by mutations in the PIK3CA gene that result in the malformation and overgrowth of various parts of the body. A new report to be published January 26 in the Journal of Experimental Medicine (JEM) describes the successful treatment of two young infants with PROS using the breast cancer drug alpelisib. The Rockefeller University Press https://www.newswise.com/articles/fast-tracked-stroke-drug-for-humans-shows-promise-in-mice-that-it-might-also-prove-a-powerful-tool-against-dementia/?sc=rsin https://www.newswise.com/articles/fast-tracked-stroke-drug-for-humans-shows-promise-in-mice-that-it-might-also-prove-a-powerful-tool-against-dementia/?sc=rsin Wed, 01 Dec 2021 10:25:09 EST USC study published in the Journal of Experimental Medicine shows that experimental drug protects against injury caused by tiny blood clots in the brain's white matter, which can accumulate over time and lead to cognitive decline The Rockefeller University Press https://www.newswise.com/articles/open-access-content-from-rockefeller-university-press-now-available-on-researchgate/?sc=rsin https://www.newswise.com/articles/open-access-content-from-rockefeller-university-press-now-available-on-researchgate/?sc=rsin Tue, 23 Nov 2021 11:00:26 EST ResearchGate and Rockefeller University Press (RUP) today announced the completion of the first phase of a content syndication pilot partnership. ResearchGate users can now find full-text Immediate OA articles and a subset of five years of archival content published in the Journal of Cell Biology (JCB), Journal of Experimental Medicine (JEM), and Journal of General Physiology (JGP) between May 2016 and April 2021 on the network -- approximately 2,800 articles in total. The Rockefeller University Press https://www.newswise.com/articles/by-putting-cancer-cells-to-sleep-new-drug-could-prevent-tumor-metastasis/?sc=rsin https://www.newswise.com/articles/by-putting-cancer-cells-to-sleep-new-drug-could-prevent-tumor-metastasis/?sc=rsin Tue, 23 Nov 2021 10:00:21 EST A new therapeutic approach prevents the growth of metastatic tumors in mice by forcing cancer cells into a dormant state in which they are unable to proliferate. The study, published November 23 in the Journal of Experimental Medicine (JEM), could lead to new treatments that prevent the recurrence or spread of various cancer types, including breast cancer and head and neck squamous cell carcinoma (HNSCC). The Rockefeller University Press https://www.newswise.com/articles/yale-researchers-develop-rna-based-therapy-that-clears-sars-cov-2-from-mice/?sc=rsin https://www.newswise.com/articles/yale-researchers-develop-rna-based-therapy-that-clears-sars-cov-2-from-mice/?sc=rsin Wed, 10 Nov 2021 10:30:23 EST Researchers at Yale School of Medicine have discovered that an RNA molecule that stimulates the body's early antiviral defense system can protect mice from a range of emerging SARS-CoV-2 variants. The study, published today in the Journal of Experimental Medicine (JEM), could lead to new treatments for COVID-19 in immunocompromised patients, as well as providing an inexpensive therapeutic option for developing countries that currently lack access to vaccines. The Rockefeller University Press