Medical Drug Research Blog written by pharmacist

tag:blogger.com,1999:blog-2476705825949587878Tue, 19 May 2026 09:47:36 +0000Cytotoxic HIV-specific immunotherapy;immunotoxin 3B3-PE38HIV vaccine by step by step immunization strategyHow to reduce cholesterol; hyperlipidemic drugs;hypercholesterolemia drugsTHIS PAGE IS DEDICATED FOR SHARING KNOWLAGE ON HIV FOR RESERCH FETERNITY FOR PROVIDING SOLUTION AS SOON AS POSSIBLE AND MAKE THIS WORLD FREE OF THIS DISEASETest for HIVVitamin D TB; Mycobacterium tuberculosis; Biomarker interleukin-32Medical Drug Research Blog written by pharmacist Medical Drug Reasearch latest information on newer medical treatment new drug research drug updateshttps://bvwaghmare.blogspot.com/noreply@blogger.com (Author)Blogger103125tag:blogger.com,1999:blog-2476705825949587878.post-331155114014539787Wed, 05 Apr 2023 08:39:00 +00002023-06-28T04:17:17.660-07:00How to deal with Recurrent infection serge of corona virus.How to deal with Recurrent infection serge of corona virus. Last years in 2020 and 2021 we have faced lock down to protect ourselves from corona virus and its life threatening infection. Many of us went through vaccination and even after vaccination lives were lost due corona infection. Corona infection acts on the blood and blood vessels, triggering interleukin flair that caused damage to https://bvwaghmare.blogspot.com/2023/04/how-to-deal-with-recurrent-infection.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-4045247251198836437Sat, 24 Dec 2022 18:30:00 +00002023-07-22T21:06:40.995-07:00Which are the currently available medicines for treating HIV infection ? What is HAART ?</  Which are the currently available medicines for treating HIV infection ? What is HAART ? There are following class of Medicines available so far for treatment of HIV infection. HAART is made up of different kinds of drugs comprising from following categories: 1. Nucleoside Reverse Transcriptase Inhibitors (NRTIs) 2. Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs) 3. Protease https://bvwaghmare.blogspot.com/2010/11/which-are-currently-available-medicines.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-7880212932932591399Sat, 24 Dec 2022 18:30:00 +00002023-06-28T04:21:11.313-07:00New Class of Antiretroviral Capsid formation inhibitor that provides option for treatment to Multi Drug Resistant HIV 1 Infection New Class of Antiretroviral drug Lencapavir to provide lifesaving remedy for HIV infected people having Multi Drug Resistant HIV HIV virus can infect the human body through a mechanism of infection, and it reproduces in the human body increasing its number to lacs of viral copies in blood, and making lives of infected persons difficult. For the increased level of HIV Viral load doctors https://bvwaghmare.blogspot.com/2022/12/new-class-of-antiretroviral-capsid.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-2501600898838496554Tue, 11 Jan 2022 10:19:00 +00002022-12-24T09:51:23.586-08:00Opoidal drug should be contraindicated in COIVD 19Dextromethorphan a drug which is an analog of morphine and consist the main maopholine ring in its molecule which is also part of all opoid drugs.It is found that the Sigma1 sites on the viral particles are bind with Dextromethorphan in a manner that helps virus to replicate.Also the lysosome which impart cellular Immunity by embibing and dissolving viral particles, formed are smaller in size so https://bvwaghmare.blogspot.com/2022/01/opoidal-drug-should-be-contraindicated.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-295984697222880102Tue, 31 Mar 2020 12:44:00 +00002022-12-17T12:09:39.242-08:00Repurposing of existing Drugs in prevention and mitigation of Novel Corona Virus 19 Which are best candidates from existing drug molecules for use as antiviral drug against Novel Corona Virus 19. 1) Existing drugs which hold molecular similarities and properties which can potentially exhibit antiviral activity in treatment of novel corona virus 19 are listed below. 2) Diethylcarbamazine (DEC): Diethylcarbamazine(DEC) as Antiviral or in the https://bvwaghmare.blogspot.com/2020/03/repurposing-of-existing-drugs-in.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-4437589064940056566Mon, 23 Mar 2020 17:18:00 +00002020-09-06T06:02:38.752-07:00Steps in prevention of Corona Virus 19 spread How to prevent spread of Corona Virus 19 ? Following steps will help to save lives of millions of people from getting SARS COV 19 infection. An Alcohol or Isopropyl Alcohol based hand sanitizer may not be so effective as  that of Dilute  Solution of bleaching powder. Prefer Dilute solution of bleaching powder allow it's contact for minimum 10 minutes. 1.Keep yourself away from a https://bvwaghmare.blogspot.com/2020/03/steps-in-prevention-of-corona-virus-19.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-3745923084749786892Mon, 02 Mar 2020 15:06:00 +00002022-12-17T12:12:08.860-08:00Prevention and mitigation strategy for novel coronavirus infection How to prevent corona virus infection spread. Following techniques will provide significant protection from protecting an individual from getting COV19  infection even while living with person infected with Novel Corona Virus. These techniques are not adapted in china and other countries hence the spread and lethal impact of the outbreak is very huge and life threatening. In emergency https://bvwaghmare.blogspot.com/2020/03/prevention-and-mitigation-strategy-for.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-1068762650007342379Sun, 29 Nov 2015 18:13:00 +00002023-04-01T12:24:04.340-07:00HIV vaccine by step by step immunization strategyHIV vaccine by step by step immunization strategy Antibodies isolated from HIV positive individuals were successful in preventing proliferation of HIV in animal, while it was not preventing HIV in the infected individuals. Advertisement Pharma Guidelines  What is that difference that antibodies work against HIV in animal model, is now key towards development of a successful vaccination program against HIV. HIV https://bvwaghmare.blogspot.com/2015/11/hiv-vaccine-by-step-by-step.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-1242803075984631840Thu, 06 Nov 2014 17:34:00 +00002023-06-28T04:22:50.012-07:00How to reduce cholesterol; hyperlipidemic drugs;hypercholesterolemia drugsHow to reduce cholesterol medicines for increased cholesterol How to reduce cholesterol? Why medicines for cholesterol must be taken? Which medicines are given to reduce cholesterol? Higher level of cholesterol in body is very dangerous as it may block coronary arteries and may cause heart failure, cholesterol tend to form fatty plaques in veins and arteries, which when dislodged may occlude blood flow, if the artery that get occlusion is one that supply https://bvwaghmare.blogspot.com/2014/11/how-to-reduce-cholesterol-medicines-for.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-805410341234418006Sun, 07 Sep 2014 09:45:00 +00002015-09-16T21:25:48.319-07:00Vitamin D TB; Mycobacterium tuberculosis; Biomarker interleukin-32Protein that protect from TB infection developing in to lung infection Biomarker that will help predict if a person will develop fetal lung disease associated with TB infection and can be used to treat Mycobacterium tuberculosis infection. Every individual who encounter Mycobacterium tuberculosis infection do not develop an active form of TB, such individuals may test positive for Mycobacterium tuberculosis infection or antibody test. A protein interleukin-32 https://bvwaghmare.blogspot.com/2014/09/protein-that-protect-from-tb-infection.htmlnoreply@blogger.com (Author)1tag:blogger.com,1999:blog-2476705825949587878.post-7451041057919239353Tue, 02 Sep 2014 18:21:00 +00002015-06-20T13:35:44.032-07:00HIV neutralising antibodies for passive immunization. Advanced treatment of HIV infection with HIV neutralizing antibodies under development. Anti retroviral drugs must not be discontinued so as to keep HIV viral load under control to maintain quality of life, still many patients discontinue taking drugs for many reasons like anti retroviral drugs have their own set of side effects and complications, availability. Now such patients have better https://bvwaghmare.blogspot.com/2014/09/hiv-neutralising-antibodies-for-passive.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-7528381869539193732Tue, 28 Jan 2014 14:38:00 +00002023-04-01T11:56:35.907-07:00Cytotoxic HIV-specific immunotherapy;immunotoxin 3B3-PE38Immunotoxin destroys HIV cells novel approach in antiretroviral therapy New class of antiretroviral drug being developed that destroys HIV infected human cells hidden deep inside tissues. Bacterial toxin which can eliminate tissue cells responsible for proliferation of HIV. If you refer this page you will come to know that there are drugs available to treat HIV virus infection by attacking almost at all stages of infection of HIV (mode of action) except one https://bvwaghmare.blogspot.com/2014/01/immunotoxin-destroys-hiv-cells-novel.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-6350342710669415196Thu, 22 Aug 2013 13:19:00 +00002015-06-20T12:07:54.196-07:00Dolutegravir The Second drug in the class of HIV integrase inhibitors Second drug in the class of HIV integrase strand transfer inhibitors approved by US FDA to treat HIV infection Until 13-Aug-2013 there was only one drug Raltegravir available under the class of HIV integrase strand transfer inhibitors, on 13-Aug-2013 US FDA approved one more drug Tivicay (dolutegravir), HIV integrase strand transfer inhibitor to treat HIV infection. It is found to be https://bvwaghmare.blogspot.com/2013/08/dolutegravir-second-drug-in-class-of.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-1428513746505263181Thu, 22 Aug 2013 13:03:00 +00002015-06-20T12:10:43.772-07:00Antiretroviral drugs available to treat HIV infection Details of Antiretroviral drugs.  1) Nucleoside Reverse Transcriptase Inhibitors (NRTIs) : In this class there are about thirteen drugs available. 2) Nonnucleoside Reverse Transcriptase Inhibitors (NNRTIs) : In this category Five drugs are available 3) Protease Inhibitors (PIs) : In this category 10 Drugs are available. 4) Fusion Inhibitors : One drug is available 5) Entry Inhibitors - https://bvwaghmare.blogspot.com/2013/08/antiretroviral-drugs-available-to-treat.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-8996209886925899378Sun, 13 Jan 2013 16:34:00 +00002016-06-19T20:04:35.579-07:00New Drug for Non Infectious Diarrhea Associated with antiretroviral drug treatment in HIV infection Second botanical drug approved by US FDA for symptomatic relief from diarrhea associated with HIV infection and its drug treatment. Symptomatic relief form diarrhea incase HIV infection, is very important for continuation of antiretroviral drug therapy, as antiretroviral drug therapy itself can cause diarrhea , and it is one of reason why many tend to stop HIV drugs just to get relief https://bvwaghmare.blogspot.com/2013/01/new-drug-for-non-infectious-diarrhea.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-2235743337330804366Thu, 09 Aug 2012 23:55:00 +00002015-06-20T12:11:02.861-07:003D Structure of an intermediate protein in infection process of HIV virus to CD4 cell reveled New intermediate protein which facilitate attachment of HIV over CD4 and its 3D structure reveled.  An intermediate temporary protein found in the process of infection of HIV virus to CD4 cell, this protein can be used in the development of vaccine against HIV. This temporary protein is occurs just before the attachment of HIV virus to CD4 cell. The finding of this intermediatehttps://bvwaghmare.blogspot.com/2012/08/3d-structure-of-intermediate-protein-in.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-8918171765689471532Wed, 20 Jun 2012 10:36:00 +00002015-06-20T13:36:50.600-07:00Protein which can inhibit HIV virus attachment and entry in to new CD4 cells. Protein derived from platelet is found to exhibit broad spectrum HIV inhibitory properties. There are few sites over HIV virus which are unique and have great potential as targets for new drugs and HIV neutralizing antibodies, these sites so far are not explored as new targets for new antiretroviral drugs, now this research finding will certainly open doors for development of drugs and HIV https://bvwaghmare.blogspot.com/2012/06/protein-which-can-inhibit-hiv-virus.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-539853440141802033Fri, 20 Apr 2012 12:29:00 +00002015-06-20T12:11:17.876-07:00HIV vaccine reasearch heading towards success Antibodies of class Immunoglobulin G (Ig G ) increase protection in HIV vaccine trail, provide a clue for future development of HIV vaccine . Any vaccines work by inducing production of antibodies against any infective microorganism in our body Incase of HIV, antibodies produced are not able to stop or kill HIV virus as HIV virus proteins keep on changing due to high rate of mutation and keep https://bvwaghmare.blogspot.com/2012/04/hiv-vaccine-reasearch-heading-towards.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-5983675208419898712Mon, 05 Sep 2011 18:28:00 +00002015-06-20T13:38:01.550-07:00Anti retroviral drugs of class protease inhibitors drugs and increased blood cholesterol level. Antiretroviral drugs belonging to class protease inhibitors are known to cause increase in cholesterol level in patients taking protease inhibitors drugs. Anti retroviral protease inhibitors drugs which act by inhibiting enzyme protease , this enzyme helps HIV virus in building its protein by breaking higher proteins in to smaller on, and then make use of these smaller one for buildinghttps://bvwaghmare.blogspot.com/2011/09/anti-retroviral-drugs-of-class-protease.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-7941023727160758636Tue, 30 Aug 2011 19:07:00 +00002014-06-08T02:16:16.950-07:00HIV vaccine research, B Cells can be stimulated with proteins on HIV virus region which do not change and produce antibodies which can neutralize HIV virus. National institute of health led researchers found route to guide B cells to produce antibodies against HIV which can neutralize HIV the research provides a clue for development of HIV vaccine. . Days are not far when researchers will be successful in developing a vaccine for HIV, so far there is no vaccine available against HIV, in last few years HIV vaccine research has seen https://bvwaghmare.blogspot.com/2011/08/hiv-vaccine-research-b-cells-and-be.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-2905709672401002199Sat, 09 Jul 2011 12:27:00 +00002014-06-08T02:16:30.353-07:00Test for HIVTesting for HIV infection Tests for HIV are used to detect the presence of HIV infection in ones body, the tests can detect the HIV in blood , urine and saliva , the main principle behind these tests are detection of HIV antibodies, antigen or RNA of HIV. And the tests employed for detection are 1. ELISA 2. Western Blot 3.Polymerase Chain Reaction. 4.Rapid point of care test kits A. Home Access Express HIV-1 Test https://bvwaghmare.blogspot.com/2011/07/testing-for-hiv-infection.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-2929777057500200632Tue, 31 May 2011 18:08:00 +00002023-06-28T04:26:38.467-07:00New nonnucleoside reverse transcriptase inhibitors for treating patients who never recived any anti retroviral drug before New drug is now available for HIV positive patients who have never taken any treatment. There is a new drug development in the treatment of HIV positive individual, now a new drug is approved by US food and drugs administration , the new drug is a non nucleoside reverse transcriptase inhibitor, which can be used to lower the higher HIV 1 viral load in blood of HIV positive individuals which https://bvwaghmare.blogspot.com/2011/05/new-nonnucleoside-reverse-transcriptase.htmlnoreply@blogger.com (Author)0tag:blogger.com,1999:blog-2476705825949587878.post-2718172916002703829Mon, 30 May 2011 08:42:00 +00002013-08-21T08:20:19.535-07:00Tests for detection of HIV infection Test for HIV. Information on HIV   testing Main principle of detection of HIV infection is presence of antibodies against HIV virus in the HIV virus infceted individual, more reliable tests identify presence of HIV genetic material or RNA for detection of presence of HIV virus infection. ELISA test detect the presence of antibodies against HIV virus in ones blood, if ELISA test https://bvwaghmare.blogspot.com/2011/02/tests-for-detection-of-hiv-infection.htmlnoreply@blogger.com (Author)1tag:blogger.com,1999:blog-2476705825949587878.post-7930557735168390217Sun, 29 May 2011 21:42:00 +00002013-08-21T08:21:32.870-07:00Dr. A H Bandivdekar finds the inhibitor for sexual transmission of HIV virus. Dr. A H Bandivdekar finds the inhibitor for sexual transmission of HIV virus. Dr. A H Bandivdekar Indian scientist found the exact way by which HIV virus gains entry in to human blood in sexual transmission of HIV virus, which is one of the biggest reason for HIV virus infections and AIDS. We have few great out comes about process HIV virus infection. Amongst them Dr. A H Bandivdekar’s https://bvwaghmare.blogspot.com/2011/01/dr-h-bandivdekar-finds-inhibitor-for.htmlnoreply@blogger.com (Author)1tag:blogger.com,1999:blog-2476705825949587878.post-720390844407267860Sun, 28 Nov 2010 14:01:00 +00002013-08-21T08:25:04.806-07:00Call For The World...For This World. Call for world AIDS Day! HIV/AIDS is one of the major issues in front of every nation today , if we do not find ways to fight against HIV it has capability to affect every family in world. HIV virus do not recognise any boundaries of any nation , it do not understand difference of languages , neither it understand differences between poor and rich , women or child or men. Neither we have https://bvwaghmare.blogspot.com/2010/11/call-for-worldfor-this-world.htmlnoreply@blogger.com (Author)0