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    <title>Integrated Supplements Blog</title>
    
    
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    <id>tag:typepad.com,2003:weblog-492917</id>
    <updated>2012-01-25T12:19:56-06:00</updated>
    <subtitle>Nutrition for Your Full Human Potential</subtitle>
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        <title>Integrated Supplements is a Proud Sponsor of the Fittest Loser Challenge</title>
        <link rel="alternate" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2012/01/integrated-supplements-is-a-proud-sponsor-of-the-fittest-loser-challenge.html" />
        <link rel="replies" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2012/01/integrated-supplements-is-a-proud-sponsor-of-the-fittest-loser-challenge.html" thr:count="0" />
        <id>tag:typepad.com,2003:post-6a00d8341cbdce53ef016761109c4a970b</id>
        <published>2012-01-25T12:19:56-06:00</published>
        <updated>2012-01-27T11:15:16-06:00</updated>
        <summary>Integrated Supplements is proud to be a sponsor, and official nutritional supplement provider, for the 2012 Fittest Loser Challenge. Now in its fourth year, The Fittest Loser Challenge is a 12-week body transformation contest presented by The Daily Herald -...</summary>
        <author>
            <name>Integrated Supplements</name>
        </author>
        <category scheme="http://www.sixapart.com/ns/types#category" term="Fittest Loser" />
        
        
<content type="xhtml" xml:lang="en-US" xml:base="http://integratedsupplements.typepad.com/integrated_supplements_bl/">
<div xmlns="http://www.w3.org/1999/xhtml"><p><br /> <a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0163003a5dc3970d-pi" style="float: right;"><img alt="FLBlogImage1" class="asset  asset-image at-xid-6a00d8341cbdce53ef0163003a5dc3970d" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0163003a5dc3970d-250wi" style="width: 250px; margin: 0px 0px 5px 5px;" title="FLBlogImage1" /></a>Integrated Supplements is proud to be a sponsor, and official nutritional supplement provider, for the 2012 Fittest Loser Challenge.</p>
<p>Now in its fourth year, The Fittest Loser Challenge is a 12-week body transformation contest presented by The Daily Herald - suburban Chicago’s largest daily newspaper.  Out of hundreds of entries, six contestants are chosen to have their lives transformed. These chosen few receive expert training and nutritional consultation from Push Fitness – a premier training studio located in Schaumburg, Illinois – as well as premium nutritional supplements from us at Integrated Supplements.  For the duration of the 12-week contest, the contestants have their progress chronicled in the pages of the Daily Herald newspaper, and the one losing the most weight during this time is crowned with the title of: “The Fittest Loser.”</p>
<p><strong>But, the best part is, you don’t have to be a Fittest Loser contestant to join in.  </strong></p>
<p>Though only six people are chosen as contestants, the challenge has inspired hundreds of individuals to lose weight, build muscle, and improve their overall health and well-being.  We want you to benefit from the same sort of expert coaching that the Fittest Loser contestants receive.  In upcoming blog articles, we’ll give you practical tips on diet, supplements, training, and you’ll join a community of like-minded people striving to be their best everyday. </p>
<p>You can do it! And we're here to help.</p>
<p><span style="color: #005d86;"><strong><span style="font-size: 11pt;">Let's Get Started </span></strong></span></p>
<p>Sign up for our blog's<a href="http://www.facebook.com/IntegratedSupplement?v=app_192229990808929" target="_self"> “Fittest Loser” RSS feed</a>, and get involved by asking questions in the comments section of these blog posts or on our Facebook page.</p>
<p>Like us on Facebook, and <a href="http://www.facebook.com/IntegratedSupplement?sk=app_197602066931325" target="_self">fill out the form here</a> to be entered to win an Integrated Supplements prize package.</p>
<p>Visit our friends at <a href="http://www.pushfitnesstraining.com/" target="_self">Push Fitness</a> and be sure to check out some of the amazing transformations their clients have undergone - if you're in Chicago's northwest suburbs, there's no better place to go for expert personal training.</p>
<p>Be inspired by reading <a href="http://www.dailyherald.com/topics/FittestLoser/" target="_self">success stories</a> from previous Fittest Loser contestants.</p>
<p>Visit our <a href="http://www.integratedsupplements.com/intsup/intsup0001.homepage" target="_self">website</a>, and find out more about Integrated Supplements products.</p>
<p>If you're interested in purchasing Integrated Supplements products, we've got a great group of online and brick-and-stores carrying our products.  <a href="http://www.integratedsupplements.com/intsup/intsup0004.where_to_buy" target="_self">You can find them here.</a></p>
<p>Let's make 2012 your best year yet!</p>
<p><a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0163001b4257970d-pi" style="float: right;"><img alt="BottleGroup" border="0" class="asset  asset-image at-xid-6a00d8341cbdce53ef0163001b4257970d" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0163001b4257970d-800wi" style="margin: 0px 0px 5px 5px;" title="BottleGroup" /></a></p>
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    </entry>
    <entry>
        <title>Green Detox Q &amp; A - Green Detox and Healthy, Radiant Skin</title>
        <link rel="alternate" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/green-detox-q-a-green-detox-and-healthy-radiant-skin.html" />
        <link rel="replies" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/green-detox-q-a-green-detox-and-healthy-radiant-skin.html" thr:count="0" />
        <id>tag:typepad.com,2003:post-6a00d8341cbdce53ef0153939d6e22970b</id>
        <published>2011-12-23T08:30:00-06:00</published>
        <updated>2011-12-23T08:30:00-06:00</updated>
        <summary>Q. How can Green Detox support healthy, radiant skin? A. There are several mechanisms by which Green Detox can support healthy, radiant skin. As with many of the benefits of sea vegetables, one mechanism may begin in the gastrointestinal tract...</summary>
        <author>
            <name>Integrated Supplements</name>
        </author>
        
        
<content type="xhtml" xml:lang="en-US" xml:base="http://integratedsupplements.typepad.com/integrated_supplements_bl/">
<div xmlns="http://www.w3.org/1999/xhtml"><p><strong><span style="color: #005d86;"> <a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0153939d64c1970b-pi" style="float: right;"><img alt="Blog_Icon_GreenDetox" class="asset  asset-image at-xid-6a00d8341cbdce53ef0153939d64c1970b" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0153939d64c1970b-250wi" style="width: 250px; margin: 0px 0px 5px 5px;" title="Blog_Icon_GreenDetox" /></a>Q. How can Green Detox support healthy, radiant skin?</span></strong></p>
<p><strong><span style="color: #005d86;">A.</span></strong> There are several mechanisms by which Green Detox can support  healthy, radiant skin. As with many of the benefits of sea vegetables, one  mechanism may begin in the gastrointestinal tract by supporting a healthy  intestinal bacterial composition.</p>
<p>Somewhat surprisingly, intestinal bacteria can play a major  role in skin health. As an example, acne and other skin conditions are often  treated with oral antibiotics which alter the bacterial population of the  intestines. Interestingly, alternative medicine practitioners often associate  acne with impaired liver function, which, as we have seen, is one consequence of  a preponderance of pathogenic intestinal bacteria (note: sea vegetables and/or  chlorophyll are not antibiotics per se – they may merely support the growth of  beneficial bacteria in the intestines at the expense of pathogenic bacteria).</p>
<p>Seaweeds also contain unique antioxidant polyphenols. In their  natural environment, marine polyphenols protect seaweeds against the harmful  effects of UV radiation and pollution. These substances, when consumed, may also  be able to protect our skin from the same harmful stresses.</p>
<p>In addition, the unique polysaccharides found in seaweeds may  inhibit enzymes involved in the aging of skin. As a frame of reference, oral  nutritional supplements and anti–aging topical cosmetics containing the  structural component of skin and connective tissue, hyaluronan/hyaluronic, acid  have become increasingly popular recently. Components of Wakame seaweed  (<em>Undaria Pinnatifida</em>), have been shown to inhibit hyaluronidase – the  enzyme which breaks down hyaluronan:</p>
<p><a href="http://www.jstage.jst.go.jp/article/fstr/9/1/9_25/_article" target="_blank">Study Link – Hyaluronidase–Inhibiting Polysaccharide Isolated and  Purified from Hot Water Extract of Sporophyll of <em>Undaria  pinnatifida</em>.</a></p>
<p>Also, Green Detox contains an aqueous extract of <em>Fucus  vesiculosus</em> known as Maritech® Synergy. Maritech® Synergy is a source of  powerfully protective antioxidants, and also contains a standardized amount of  fucoidan – a polysaccharide from brown seaweed known to support immune function  and healthy cell growth and repair*. Similarly to Wakame, Maritech® Synergy has  been shown to inhibit the enzymes which break down the structural components of  skin, collagen and elastin.</p>
<p><a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0153939d6580970b-pi" style="float: right;"><img alt="Green DetoxJPG" class="asset  asset-image at-xid-6a00d8341cbdce53ef0153939d6580970b" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0153939d6580970b-150wi" style="width: 150px; margin: 0px 0px 5px 5px;" title="Green DetoxJPG" /></a>It has often been noted that people in Asian cultures enjoy  youthful, radiant, and wrinkle–free skin well into advanced age. The reason may  be more than just genetic – judging by the existing research, it's likely that  regular seaweed consumption offers useful protection against signs of skin  aging, including wrinkles, blemishes and age spots.</p>
<p>As, the role of nutrition in skin health has become  increasingly recognized, research in the field has led to the creation of  various "beauty–from–within" products, or "nutricosmetics" – nutritional  supplements which, unlike traditional cosmetics and beauty aids, are taken  orally. Green Detox is a perfect example of such a product.</p>
<p><a href="http://www.integratedsupplements.com/intsup/intsup0004.where_to_buy">Find a retailer for Green Detox and other Integrated Supplements Products</a></p>
<p><span style="color: #005d86;"> <strong>Related Posts:</strong></span></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-green-detox.html">Green Detox Q &amp; A - What is Green Detox?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-fucoidan.html">Green Detox Q &amp; A - What is Fucoidan?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-chlorella.html">Green Detox Q &amp; A - What is Chlorella?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-benefits.html">Green Detox Q &amp; A - Benefits</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-green-detox-versus-other-detox-supplements.html">Green Detox Q &amp; A - Green Detox Versus Other Detox Supplements</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-green-detox-versus-other-greens-supplements.html">Green Detox Q &amp; A - Green Detox Versus Other Greens Supplements</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-are-toxins-a-real-threat.html">Green Detox Q &amp; A - Are "Toxins" a Real Threat?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-food-based-toxins.html">Green Detox Q &amp; A - Food-Based Toxins</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-digestive-health-and-intestinal-detoxification.html">Green Detox Q &amp; A - Digestive Health and Intestinal Detoxification</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-green-detox-and-weight-loss.html">Green Detox Q &amp; A - Green Detox and Weight Loss</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-green-detox-and-hormonal-health.html">Green Detox Q &amp; A - Green Detox and Hormonal Health</a></p>
<p> </p></div>
</content>



    </entry>
    <entry>
        <title>Green Detox Q &amp; A - Green Detox and Hormonal Health</title>
        <link rel="alternate" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/green-detox-q-a-green-detox-and-hormonal-health.html" />
        <link rel="replies" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/green-detox-q-a-green-detox-and-hormonal-health.html" thr:count="0" />
        <id>tag:typepad.com,2003:post-6a00d8341cbdce53ef0162fcf2cb95970d</id>
        <published>2011-12-20T08:30:00-06:00</published>
        <updated>2011-12-20T08:30:00-06:00</updated>
        <summary>Q. How can Green Detox support hormonal health? A. Research has shown that Japanese women have longer menstrual cycles and lower serum estrogen levels than Western women. Not coincidentally, Japanese women are known to have among the lowest rates of...</summary>
        <author>
            <name>Integrated Supplements</name>
        </author>
        
        
<content type="xhtml" xml:lang="en-US" xml:base="http://integratedsupplements.typepad.com/integrated_supplements_bl/">
<div xmlns="http://www.w3.org/1999/xhtml"><p><span style="color: #005d86;"><strong> <a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef015437710817970c-pi" style="float: right;"><img alt="Blog_Icon_GreenDetox" class="asset  asset-image at-xid-6a00d8341cbdce53ef015437710817970c" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef015437710817970c-250wi" style="width: 250px; margin: 0px 0px 5px 5px;" title="Blog_Icon_GreenDetox" /></a>Q. How can Green Detox support hormonal health?</strong></span></p>
<p><span style="color: #005d86;"><strong>A. </strong></span>Research has shown that Japanese women have longer menstrual  cycles and lower serum estrogen levels than Western women. Not coincidentally,  Japanese women are known to have among the lowest rates of hormone–related  breast, endometrial, and ovarian cancers in the world. It's reasonable to wonder  if a seaweed–rich diet may be one reason why.</p>
<p>Recent preliminary research has shown that the brown seaweed,  <em>Fucus vesiculosus</em>, may be able to reduce the body's burden of the potent  estrogen 17–ß estradiol, while increasing levels of the protective hormone,  progesterone, in pre–menopausal women:</p>
<p><a href="http://www.biomedcentral.com/1472%E2%80%936882/4/10" target="_blank">Study Link – The effect of Fucus vesiculosus, an edible brown  seaweed, upon menstrual cycle length and hormonal status in three pre–menopausal  women: a case report.</a></p>
<p><a href="http://171.66.122.67/cgi/content/abstract/2005/1/1224" target="_blank">Study Link – The anti–estrogenic effects of the brown seaweed,  Fucus vesiculosus: implications in prevention of estrogen–dependent cancers.</a></p>
<p>Animal studies have shown similar findings:</p>
<p><a href="http://jn.nutrition.org/content/135/2/296.full" target="_blank">Study Link – Brown Kelp Modulates Endocrine Hormones in Female  Sprague–Dawley Rats and in Human Luteinized Granulosa Cells.</a></p>
<p>At this time, researchers aren't certain as to exactly how  seaweeds exert their effects on hormonal health. Some have proposed that  seaweed's ability to alter cholesterol levels may be responsible (steroid  hormones are produced from cholesterol, so less available cholesterol could  alter hormone synthesis).</p>
<p>It's more likely, however, that seaweed's effect on  gastrointestinal/liver function is responsible. We've already seen how some  seaweeds can reduce the production of enzymes which interfere with hormonal  detoxification. Additionally, pathogenic bacteria in the intestines presents a  chronic burden upon the liver (elements from these bacteria are continually  absorbed across the intestinal barrier and into portal circulation where the  liver detoxifies them before they can enter general circulation).</p>
<p>Many substances which alter the bacterial population of the  intestines are well–known to alter hormonal metabolism by the liver.  Antibiotics, for example (which take a large burden off of the liver by killing  pathogenic intestinal bacteria), are well–known to interfere with the action of  birth–control pills. In the absence of pathogenic intestinal bacteria, the liver  is far more capable of detoxifying (thus rendering inactive) such exogenous  hormones. With the unique prebiotic and bowel–cleansing elements found in  seaweed, there's reason to believe that such foods can aid in the natural  detoxification endogenous hormones as well. It seems clear that more research  into this aspect of seaweeds and sea vegetables is needed.</p>
<p><span style="color: #005d86;"><strong>Q. What about men? Can Green Detox improve men's hormonal health as well?</strong></span></p>
<p><span style="color: #005d86;"><strong>A.</strong></span> It seems likely that it can. Excess endogenous and exogenous  (i.e., environmental) estrogens pose a risk to men's health as well as women's.  If seaweeds can aid in the detoxification of estrogens indirectly by their bowel  cleansing, and liver–sparing effects, men would be likely to benefit as well as  women.</p>
<p>It's entirely possible that components in sea vegetables may  even provide unique benefits for bodybuilding and muscle growth. Intense  exercise is well known to tax the immune system, and it's not just steroid–using  bodybuilders with compromised liver function – intense exercise, itself, can tax  the liver as well.</p>
<p>All livestock farmers know that the use of antibiotics not only  reduces incidence of infection, but also results in enhanced growth and feed  efficiency in animals (i.e., the animal's growth is enhanced on relatively less  food intake). In recent years, however, the livestock industry has been under  increased pressure to minimize or eliminate the use of traditional antibiotics,  as these drugs may lead to the development of antibiotic–resistant bacteria – a  potential danger to both humans and animals. Though not antimicrobial per se,  various seaweeds have begun to be investigated as immunomodulating and  growth–promoting feed additives:</p>
<p><a href="http://pas.fass.org/content/17/4/217.full.pdf+html" target="_blank">Study Link – Alternatives to Conventional Antimicrobials in Swine  Diets.</a></p>
<p>Empirically, farmers have often noted that the nutritional  benefits of seaweed are greater than would be imagined from the nutritional  composition of the seaweed itself. This may be because the unique fibers in  seaweed create a bacterial environment in the intestines which facilitates the  absorption and utilization of nutrients.</p>
<p><a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef015437710ba9970c-pi" style="float: right;"><img alt="Green DetoxJPG" class="asset  asset-image at-xid-6a00d8341cbdce53ef015437710ba9970c" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef015437710ba9970c-150wi" style="width: 150px; margin: 0px 0px 5px 5px;" title="Green DetoxJPG" /></a>Agricultural studies have also found that conception rates of  cattle are often increased markedly when bulls are given seaweed as part of  their rations. Researchers conducting these studies found that bulls exhibited a  "very high" increase in the number of live sperm, as well as a "much greater"  durability of semen when fed seaweed.</p>
<p>Additionally, it's interesting to note that in Caribbean folk  medicine, seaweed–containing mixtures have been used as aphrodisiacs to enhance  virility.</p>
<p>Due to brown seaweed's ability to support so many aspects of  health and detoxification, these unique foods may be able to support healthy  hormonal levels in men and women alike.</p>
<p><a href="http://www.integratedsupplements.com/intsup/intsup0004.where_to_buy">Find a retailer for Green Detox and other Integrated Supplements Products</a></p>
<p><span style="color: #005d86;"> <strong>Related Posts:</strong></span></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-green-detox.html">Green Detox Q &amp; A - What is Green Detox?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-fucoidan.html">Green Detox Q &amp; A - What is Fucoidan?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-chlorella.html">Green Detox Q &amp; A - What is Chlorella?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-benefits.html">Green Detox Q &amp; A - Benefits</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-green-detox-versus-other-detox-supplements.html">Green Detox Q &amp; A - Green Detox Versus Other Detox Supplements</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-green-detox-versus-other-greens-supplements.html">Green Detox Q &amp; A - Green Detox Versus Other Greens Supplements</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-are-toxins-a-real-threat.html">Green Detox Q &amp; A - Are "Toxins" a Real Threat?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-food-based-toxins.html">Green Detox Q &amp; A - Food-Based Toxins</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-digestive-health-and-intestinal-detoxification.html">Green Detox Q &amp; A - Digestive Health and Intestinal Detoxification</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-green-detox-and-weight-loss.html">Green Detox Q &amp; A - Green Detox and Weight Loss</a></p>
<p> </p></div>
</content>



    </entry>
    <entry>
        <title>Green Detox Q &amp; A - Green Detox and Weight Loss</title>
        <link rel="alternate" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/green-detox-q-a-green-detox-and-weight-loss.html" />
        <link rel="replies" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/green-detox-q-a-green-detox-and-weight-loss.html" thr:count="0" />
        <id>tag:typepad.com,2003:post-6a00d8341cbdce53ef0153939d37e3970b</id>
        <published>2011-12-16T08:30:00-06:00</published>
        <updated>2011-12-16T08:30:00-06:00</updated>
        <summary>Q. Can Green Detox help with weight loss? A. There are several reasons why Green Detox may be particularly helpful with weight loss. Most obviously, Green Detox is a concentrated source of nutrients. During periods of caloric restriction and increased...</summary>
        <author>
            <name>Integrated Supplements</name>
        </author>
        
        
<content type="xhtml" xml:lang="en-US" xml:base="http://integratedsupplements.typepad.com/integrated_supplements_bl/">
<div xmlns="http://www.w3.org/1999/xhtml"><p><span style="color: #005d86;"><strong> <a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0162fcf28c9a970d-pi" style="float: right;"><img alt="Blog_Icon_GreenDetox" class="asset  asset-image at-xid-6a00d8341cbdce53ef0162fcf28c9a970d" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0162fcf28c9a970d-250wi" style="width: 250px; margin: 0px 0px 5px 5px;" title="Blog_Icon_GreenDetox" /></a>Q. Can Green Detox help with weight loss?</strong></span></p>
<p><span style="color: #005d86;"><strong>A.</strong></span> There are several reasons why Green Detox may be particularly  helpful with weight loss. Most obviously, Green Detox is a concentrated source  of nutrients. During periods of caloric restriction and increased energy  expenditure (i.e., exercise), concentrated sources of nutrients can supply for  the body's micronutrient needs without supplying additional calories.</p>
<p>As it contains sea vegetables, Green Detox is a particularly  rich source of iodine and other trace minerals. Iodine is a necessary nutrient  for proper thyroid function and healthy metabolism*, but the detoxifying  properties of Green Detox may also play a role in supporting proper thyroid  function, metabolism, and weight loss*.</p>
<p>Many environmental chemicals happen to be fat–soluble, and are  largely stored in our bodies' adipose (fatty) tissue. Because adipose tissue is  relatively metabolically inactive, storage of metabolism–disrupting toxins in  fat cells may be our bodies' way of protecting valuable metabolic machinery from  disruption via these toxins. And, because of their ubiquity and resistance to  degredation, it's safe to say that nearly every man, woman, and child in the  industrialized world has some degree of toxic burden from these environmental  chemicals.</p>
<p>Studies have found that weight loss (i.e., losing bodyfat)  causes large amounts of these stored pesticides and other fat–soluble  environmental toxins to be released from storage in adipose tissue and into the  bloodstream where they can then do great damage:</p>
<p><a href="http://www.ncbi.nlm.nih.gov/pubmed/11093288?dopt=Abstract" target="_blank">Study Link – Body weight loss increases plasma and adipose tissue  concentrations of potentially toxic pollutants in obese individuals.</a></p>
<p>Quote from the above study:</p>
<blockquote>
<p><span style="color: #666666;"><em>Organochlorine pollutants were found in  every subject and all 19 compounds detected had their plasma concentration  increased following treatment (mean body weight loss 9.5 kg), 15 of which were  statistically significant... Body weight loss increases plasma and subcutaneous  adipose tissue concentrations of organochlorine pesticides and PCBs in obese  subjects. These results raise concerns about an undesired and potentially  harmful side effect of weight loss in some obese patients who seem to be at  greater risk of health problems than leaner subjects since they show higher  organochlorine body burden.</em></span><em> </em></p>
</blockquote>
<p>Where the weight loss they experience is often so dramatic,  people who have undergone bariatric weight loss surgery are at particular risk  of harm from fat–soluble toxins stored in adipose tissue:</p>
<p><a href="http://www.springerlink.com/content/60022m76182v2493/" target="_blank">Study Link – Increased Plasma Levels of Toxic Pollutants  Accompanying Weight Loss Induced by Hypocaloric Diet or by Bariatric  Surgery.</a></p>
<p>Quote from the above study:</p>
<blockquote>
<p><span style="color: #666666;"><em>This weight loss yielded significant  increases in total plasma organochlorine concentration (increase of 23.8% for  obese and 51.8% for morbidly obese individuals). For morbidly obese individuals,  the weight loss at 1 year after surgery (46.3%) yielded a 388.2% increase in  total plasma organochlorine concentration.</em></span><em> </em></p>
</blockquote>
<p>The thyroid gland (and the cellular function of thyroid  hormone) is particularly inhibited by organochlorines and related chemicals. If  these chemicals flood the bloodstream during weight loss, it's easy to see how  this toxic burden could impair the metabolism, and may quickly bring weight loss  to a screeching halt. Studies have found that this does, indeed, happen during  periods of weight loss:</p>
<p><a href="http://toxsci.oxfordjournals.org/content/67/1/46.full" target="_blank">Study Link – Associations between Weight Loss–Induced Changes in  Plasma Organochlorine Concentrations, Serum T3 Concentration, and Resting  Metabolic Rate.</a></p>
<p>Quote from the above study:</p>
<blockquote>
<p><span style="color: #666666;"><em>Organochlorine compounds are released  from body fat into the bloodstream during weight loss. Because these compounds  may impair thyroid status, which is implicated in the control of resting  metabolic rate (RMR), the aim of this study was to determine if the augmentation  in plasma organochlorine concentrations might be associated with the decrease in  serum T3 concentration and RMR observed in response to body weight loss... In  conclusion, organochlorines released in plasma during weight loss are associated  with the documented decrease in serum T3 concentration and  RMR.</em></span><em> </em></p>
</blockquote>
<p>It's well–known that those who diet often reach a "plateau"  where metabolism slows down and weight loss stops regardless of dieting efforts.  It has often been thought that reduced caloric intake is solely responsible for  this metabolic slowdown, but the above research provides strong evidence that it  may be the toxic burden released during fat loss which is also largely  responsible.</p>
<p>To ensure that the fat–burning machinery of the metabolism  continues to run smoothly, dieting and exercise efforts should always be  accompanied by practices – such as supplementation with Green Detox – which  facilitate the body's detoxification of organochlorines and other fat–soluble  toxins.*</p>
<p>Yet another way in which Green Detox may be able to support  weight loss is by supporting beneficial bacterial populations in the intestines.  Emerging research gives reason to believe that the bacterial composition of the  intestines has far–reaching effects on overall health.</p>
<p>Generally speaking, dietary fiber is composed of indigestible  starch from plant foods. It's well–known that fiber can support digestive health  and regularity, but until recently, even scientists themselves hadn't realized  that dietary fiber is capable of impacting literally every aspect of health.</p>
<p>Dietary fibers are composed of different types of sugars with  widely varying molecular arrangements. While all dietary fiber is indigestible  to humans, different types of fiber act as fuel sources to "feed" and support  the growth of different species of bacteria in the intestines.</p>
<p>Fibers which support the growth of certain strains of  beneficial bacteria in the intestines have been dubbed prebiotics, and have been  the subject of intensive study in recent years. Seaweeds happen to contain  unique prebiotic fibers and polysaccharides not found in any land–based plant  food:</p>
<p><a href="http://www.ncbi.nlm.nih.gov/pubmed/20714423" target="_blank">Study Link – Prebiotics from Marine Macroalgae for Human and  Animal Health Applications.</a></p>
<p>A healthy bacterial environment in the intestines has been  linked to a reduced risk of obesity and metabolic syndrome, appetite reduction,  and even positive changes in mood–related symptoms. As the research unfolds,  it's becoming clear that dietary fiber is far more than just the "roughage" that  sweeps out our insides.</p>
<p><a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0162fcf28dd8970d-pi" style="float: right;"><img alt="Green DetoxJPG" class="asset  asset-image at-xid-6a00d8341cbdce53ef0162fcf28dd8970d" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0162fcf28dd8970d-150wi" style="width: 150px; margin: 0px 0px 5px 5px;" title="Green DetoxJPG" /></a>Studies have found a fascinating relationship between  intestinal bacterial populations and obesity. Certain types of intestinal  bacteria – found in obese individuals, but not in their lean counterparts – may  be particularly efficient at extracting food calories and facilitating their  storage in adipose tissue. In addition, intestinal bacteria uniquely associated  with obesity may trigger the systemic inflammation and fatty liver associated  with elevated blood lipids and metabolic syndrome:</p>
<p><a href="http://mayoclinicproceedings.com/content/83/4/460.short" target="_blank">Study Link – Gut Microbiota and Its Possible Relationship With  Obesity.</a></p>
<p>Quote from the above study:</p>
<blockquote>
<p><span style="color: #666666;"><em>...the gut bacterial flora of obese  mice and humans include fewer Bacteroidetes and correspondingly more Firmicutes  than that of their lean counterparts, suggesting that differences in caloric  extraction of ingested food substances may be due to the composition of the gut  microbiota. Bacterial lipopolysaccharide derived from the intestinal microbiota  may act as a triggering factor linking inflammation to high–fat diet–induced  metabolic syndrome... Existing evidence warrants further investigation of the  microbial ecology of the human gut and points to modification of the gut  microbiota as one means to treat people who are overweight or  obese.</em></span><em> </em></p>
</blockquote>
<p>People in seaweed–eating cultures have been found to harbor a  unique intestinal microbiota which evolved to feed on the polysaccharides in  seaweed:</p>
<p><a href="http://www.nature.com/nature/journal/v464/n7290/full/nature08937.html" target="_blank">Study Link – Transfer of carbohydrate–active enzymes from marine  bacteria to Japanese gut microbiota.</a></p>
<p>It's likely no coincidence, therefore, that cultures consuming  seaweeds as major dietary staples (Asian cultures, for example) are often known  for their health, longevity and relative freedom from obesity and related  disorders.</p>
<p> </p>
<p><a href="http://www.integratedsupplements.com/intsup/intsup0004.where_to_buy">Find a retailer for Green Detox and other Integrated Supplements Products</a></p>
<p><span style="color: #005d86;"> <strong>Related Posts:</strong></span></p>
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<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-fucoidan.html">Green Detox Q &amp; A - What is Fucoidan?</a></p>
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<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-are-toxins-a-real-threat.html">Green Detox Q &amp; A - Are "Toxins" a Real Threat?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-food-based-toxins.html">Green Detox Q &amp; A - Food-Based Toxins</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-digestive-health-and-intestinal-detoxification.html">Green Detox Q &amp; A - Digestive Health and Intestinal Detoxification</a></p>
<p> </p></div>
</content>



    </entry>
    <entry>
        <title>Green Detox Q &amp; A - Digestive Health and Intestinal Detoxification</title>
        <link rel="alternate" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/green-detox-q-a-digestive-health-and-intestinal-detoxification.html" />
        <link rel="replies" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/green-detox-q-a-digestive-health-and-intestinal-detoxification.html" thr:count="0" />
        <id>tag:typepad.com,2003:post-6a00d8341cbdce53ef0162fcf28936970d</id>
        <published>2011-12-14T08:30:00-06:00</published>
        <updated>2011-12-14T08:30:00-06:00</updated>
        <summary>Q. How can Green Detox support digestive health and intestinal detoxification? A. Green Detox can support digestive health and intestinal detoxification in several ways. As noted previously, the prebiotic effect of seaweed polysaccharides may alter the bacterial composition of the...</summary>
        <author>
            <name>Integrated Supplements</name>
        </author>
        
        
<content type="xhtml" xml:lang="en-US" xml:base="http://integratedsupplements.typepad.com/integrated_supplements_bl/">
<div xmlns="http://www.w3.org/1999/xhtml"><p><span style="color: #005d86;"><strong> <a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0153939cfe5b970b-pi" style="float: right;"><img alt="Blog_Icon_GreenDetox" class="asset  asset-image at-xid-6a00d8341cbdce53ef0153939cfe5b970b" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0153939cfe5b970b-250wi" style="width: 250px; margin: 0px 0px 5px 5px;" title="Blog_Icon_GreenDetox" /></a>Q. How can Green Detox support digestive health and intestinal detoxification?</strong></span></p>
<p><span style="color: #005d86;"><strong>A.</strong></span> Green Detox can support digestive health and intestinal  detoxification in several ways. As noted previously, the prebiotic effect of  seaweed polysaccharides may alter the bacterial composition of the intestines to  one more supportive of health. More specifically, pathogenic intestinal bacteria  produce enzymes which convert procarcinogens into carcinogens within the  gastrointestinal tract. As an example, many substances, including hormones and  hormone–like chemicals, are conjugated to glucoronic acid for excretion from the  body. Pathogenic intestinal bacteria, however, produce the enzyme,  ß–glucoronidase, which is able to break apart glucoronic acid cojugates, thus  "re–toxifying" the chemical which would otherwise be excreted from the body.</p>
<p>Pathogenic intestinal bacteria also produce azoreductases –  enzymes which may convert azo dyes (e.g, artificial food colorings) into  carcinogenic substances, and nitro– and nitrate reductases – enzymes which have  been implicated in gastrointestinal cancer.</p>
<p>Polysaccharides from seaweeds, like other prebiotics, have been  shown to shift the population of intestinal microbiota towards more beneficial  species, thus reducing the production of these enzymes:</p>
<p><a href="http://www.sciencedirect.com/science/article/pii/S0271531701003839" target="_blank">Study Link – Effect of edible seaweeds (Undaria pinnatifida and  Porphyra ternera) on the metabolic activities of intestinal microflora in  rats.</a></p>
<p>Quote from the above study:</p>
<blockquote>
<p><span style="color: #666666;"><em>Adaptation to diets containing Nori or  Wakame was associated with changes in microbial activity that involved a  decrease on reductive and hydrolytic enzymatic activities implicated in the  conversion of procarcinogens into carcinogens. The combination of the effect on  the gut flora and a more rapid transit of feces would be expected to reduce  exposure to potential carcinogens and may have health implications for human  nutrition.</em></span><em> </em></p>
</blockquote>
<p>The process of digestion itself often produces toxic  substances. Vegetarians often note that meat, for example, can putrefy and  become toxic within the gastrointestinal tract. The existing research lends  support to this contention, although the optimal solution may not be to avoid  meat entirely, but rather to consume meats with the fibers and chlorophyll  needed to neutralize the toxins which are derived from it.</p>
<p>The components of brown seaweed, laminaran and alginate, have  been shown to reduce the production of such putrefactive compounds of digestion  including, indole, p–cresol, and sulfide:</p>
<p><a href="http://www.sciencedirect.com/science/article/pii/S0308814604005448" target="_blank">Study Link – Inhibitory effects of laminaran and low molecular  alginate against the putrefactive compounds produced by intestinal microflora in  vitro and in rats.</a></p>
<p>Quote from the above study:</p>
<blockquote>
<p><span style="color: #666666;"><em>In the case of rats fed diet containing  2% (w/w) laminaran or low molecular alginate, the fermentation pattern agreed  with that of the in vitro experiment. Laminaran suppressed indole, p–cresole and  sulfide, significantly. These putrefactive compounds, in rats fed low molecular  alginate, also tended to be lower. These results suggest that the fermentation  of laminaran by intestinal bacteria suppresses the putative risk markers for  colon cancer.</em></span><em> </em></p>
</blockquote>
<p>Emerging research also suggests that some naturally–occurring  food–based chemicals, called lectins, may irritate the gastrointestinal tract by  attaching to sugars found in the cellular structure of the intestinal lining  (these cellular sugars are different than the sugars commonly used by the body  for energy). By binding to these sugars, lectins may interfere with proper  cellular communication, and may also trigger inflammation which may manifest as  gastrointestinal distress.</p>
<p>It's probably no coincidence that some of the foods which are  most apt to cause digestive problems – such as wheat (gluten), beans, and  legumes – also contain high amounts of particularly irritating lectins:</p>
<p><a href="http://www.jbc.org/content/256/13/6633.short" target="_blank">Study Link – The carbohydrate–binding specificity of pea and  lentil lectins. Fucose is an important determinant.</a></p>
<p><a href="http://www.springerlink.com/content/l11wk4h003345v53/" target="_blank">Study Link – The lectin properties of gluten as the basis of the  pathomechanism of gluten–sensitive enteropathy.</a></p>
<p>Interestingly, however, the same cellular sugar molecules to  which lectins bind can also be found in some foods. Seaweeds such as Fucus  vesiculosus and Undaria pinnatifada, for example, are known to contain such  sugars including fucose and mannose.</p>
<p>Traditional cultures often used seaweeds as folk remedies for  digestive disturbances, and modern researchers have proposed that the  consumption of the unique sugars in seaweeds may act as a "decoy" for the  attachment of harmful food–based lectins. In other words, lectins may bind to  the sugars found in seaweeds instead of these same sugars located on the cells  of the intestinal lining. It's important to note, also, that the health–damaging  effects of lectins may not be limited to the gastrointestinal system – as they  damage the structural integrity of the intestinal barrier, lectins are capable  of entering general circulation where they may attach to other tissues (e.g.,  connective tissue, elements of the nervous system, bladder tissue, etc.). This  partly explains why seaweeds may have such far–reaching benefits for disorders  involving systemic inflammation and immune dysfunction*.</p>
<p>In addition, the ingredients in Green Detox are among nature's  richest sources of the natural detoxifier, chlorophyll. We've already seen how  chlorophyll may play a role in neutralizing the cytotoxic damage produced by  heterocyclic amines in meat. In addition to the possible presence of  heterocyclic amines, the iron–containing pigment, haem, in red meat has been  associated with an increased risk of colon cancer. One proposed reason is the  degradation of haem to cytotoxic compounds in the gastrointestinal tract.</p>
<p>The consumption of vegetables, on the other hand, has been  associated with a reduced risk of colon cancer – and it's likely that  chlorophyll plays an important role. Animal studies have found that chlorophyll  is able to prevent the toxic effects of haem in the colon:</p>
<p><a href="http://carcin.oxfordjournals.org/content/26/2/387.full" target="_blank">Study Link – Green vegetables, red meat and colon cancer:  chlorophyll prevents the cytotoxic and hyperproliferative effects of haem in rat  colon.</a></p>
<p>Population–based studies in humans seem to support this  detoxifying role of chlorophyll as well:</p>
<p><a href="http://cebp.aacrjournals.org/content/15/4/717.short" target="_blank">Study Link – Heme and Chlorophyll Intake and Risk of Colorectal  Cancer in the Netherlands Cohort Study.</a></p>
<p>Quote from the above study:</p>
<blockquote>
<p><span style="color: #666666;"><em>Our data suggest an elevated risk of  colon cancer in men with increasing intake of heme iron and decreasing intake of  chlorophyll.</em></span><em> </em></p>
</blockquote>
<p><a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0153939d016b970b-pi" style="float: right;"><img alt="Green DetoxJPG" class="asset  asset-image at-xid-6a00d8341cbdce53ef0153939d016b970b" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0153939d016b970b-150wi" style="width: 150px; margin: 0px 0px 5px 5px;" title="Green DetoxJPG" /></a>Chlorophyll may also support healthy cell growth and repair.*  Numerous studies have found chlorophyll to stimulate wound healing:</p>
<p><a href="http://www.ncbi.nlm.nih.gov/pubmed/15425708" target="_blank">Study Link – Chlorophyll and wound healing; experimental and  clinical study. </a></p>
<p>In the intestines, chlorophyll thus has the potential to  protect the delicate intestinal lining.</p>
<p>As an interesting aside relating to intestinal detoxification,  chlorophyll is also a well–known internal deodorant, and is widely used to  control odors in those with incontinence and colostomies:</p>
<p><a href="http://www.ncbi.nlm.nih.gov/pubmed/14864969" target="_blank">Study Link – Deodorization of colostomies with chlorophyll.</a></p>
<p><a href="http://www.integratedsupplements.com/intsup/intsup0004.where_to_buy">Find a retailer for Green Detox and other Integrated Supplements Products</a></p>
<p><span style="color: #005d86;"> <strong>Related Posts:</strong></span></p>
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<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-fucoidan.html">Green Detox Q &amp; A - What is Fucoidan?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-chlorella.html">Green Detox Q &amp; A - What is Chlorella?</a></p>
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<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-green-detox-versus-other-greens-supplements.html">Green Detox Q &amp; A - Green Detox Versus Other Greens Supplements</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-are-toxins-a-real-threat.html">Green Detox Q &amp; A - Are "Toxins" a Real Threat?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-food-based-toxins.html">Green Detox Q &amp; A - Food-Based Toxins</a></p>
<p> </p></div>
</content>



    </entry>
    <entry>
        <title>Green Detox Q &amp; A - Food-Based Toxins</title>
        <link rel="alternate" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/green-detox-q-a-food-based-toxins.html" />
        <link rel="replies" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/green-detox-q-a-food-based-toxins.html" thr:count="0" />
        <id>tag:typepad.com,2003:post-6a00d8341cbdce53ef0162fcf26d5a970d</id>
        <published>2011-12-12T08:30:00-06:00</published>
        <updated>2011-12-12T08:30:00-06:00</updated>
        <summary>Q. In addition to environmental chemicals, what sort of toxicity is associated with the foods we eat? A. In addition to exogenous environmental toxins (e.g., pesticide residue, antibiotic residue, etc.), toxic substances can also be produced via cooking methods, as...</summary>
        <author>
            <name>Integrated Supplements</name>
        </author>
        
        
<content type="xhtml" xml:lang="en-US" xml:base="http://integratedsupplements.typepad.com/integrated_supplements_bl/">
<div xmlns="http://www.w3.org/1999/xhtml"><p><span style="color: #005d86;"><strong> <a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef01543770b78e970c-pi" style="float: right;"><img alt="Blog_Icon_GreenDetox" class="asset  asset-image at-xid-6a00d8341cbdce53ef01543770b78e970c" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef01543770b78e970c-250wi" style="width: 250px; margin: 0px 0px 5px 5px;" title="Blog_Icon_GreenDetox" /></a>Q. In addition to environmental chemicals, what sort of toxicity is associated with the foods we eat?</strong></span></p>
<p><span style="color: #005d86;"><strong>A.</strong></span> In addition to exogenous environmental toxins (e.g., pesticide  residue, antibiotic residue, etc.), toxic substances can also be produced via  cooking methods, as well as internally due to the inefficient digestion of  foods. As examples, altered protein structures from meats cooked at high  temperatures are known to contain potentially harmful substances called  heterocyclic amines (HCAs), and starch–based foods cooked at high temperatures  are known to contain a similarly harmful substance, acrylamide. As we shall see,  even food–based nutrients such as iron pose a toxicity risk in some situations.</p>
<p>In the broadest sense, it could be said that almost all foods  pose some toxicity risk. If we tried to completely avoid food–based toxins, the  result would be a near–starvation diet – obviously not a valid solution. It's  important to remember as well, that unlike modern agricultural chemicals,  food–based toxins are nothing new to our food supply. Our primitive ancestors,  for example, likely cooked meats over an open flame, without succumbing to the  modern diet–related disorders often associated with such practices.</p>
<p>For this reason, rather than attempting to engineer an overly  restrictive and unbalanced diet to avoid food–based toxins, it makes more sense  to investigate protective elements which can counter–balance them. Fruits and  vegetables, for example, provide numerous protective elements against these  toxins, but most people would admit to rarely consuming these foods  sufficiently. This is just one reason that our modern burden of food–based  toxins may be greater than ever before.</p>
<p>Where food–based toxins do much of their damage in the  intestines, it's probably no coincidence that colon cancer is one of the most  characteristic diseases of the industrialized world. The intestinal damage  caused by food–based toxins may explain why so many detoxifying protocols and  supplements place such an emphasis on the use of laxatives. Merely stimulating  bowel movements, however, doesn't meaningfully address the problem. The first  step in neutralizing toxins produced by cooking and inefficient digestion  involves altering the bacterial population of the intestines to one which  fosters healthy and complete digestion of foods. Various dietary fibers and  polysaccharides have this effect as they act as a selective growth medium for  "beneficial" intestinal bacteria.</p>
<p><a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0153939cf00e970b-pi" style="float: right;"><img alt="Green DetoxJPG" class="asset  asset-image at-xid-6a00d8341cbdce53ef0153939cf00e970b" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0153939cf00e970b-150wi" style="width: 150px; margin: 0px 0px 5px 5px;" title="Green DetoxJPG" /></a>Additionally, the green plant pigment, chlorophyll (and related  chemicals), may also offer protection against many food–based and  intestinally–derived toxins. Research has found, for example, that the  administration of cruciferous vegetables, chlorophyll, and yogurt (a source of  beneficial bacteria) helped to neutralize mutagenic DNA damage to colorectal  cells caused by heterocyclic amines (HCAs) in cooked meat:</p>
<p><a href="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0018707" target="_blank">Study Link – Inhibition of Fried Meat–Induced Colorectal DNA  Damage and Altered Systemic Genotoxicity in Humans by Crucifera, Chlorophyllin,  and Yogurt.</a></p>
<p>Quote from the above study:</p>
<blockquote>
<p><span style="color: #666666;"><em>...the inhibitor diet decreased nearly  twofold the DNA damage in target colorectal cells.</em></span><em> </em></p>
</blockquote>
<p>Ultimately, the real solution to body detoxification begins  with ensuring proper digestion, thus reducing the production of food–based and  intestinally–derived toxins.</p>
<p><a href="http://www.integratedsupplements.com/intsup/intsup0004.where_to_buy">Find a retailer for Green Detox and other Integrated Supplements Products</a></p>
<p><span style="color: #005d86;"> <strong>Related Posts:</strong></span></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-green-detox.html">Green Detox Q &amp; A - What is Green Detox?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-fucoidan.html">Green Detox Q &amp; A - What is Fucoidan?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-chlorella.html">Green Detox Q &amp; A - What is Chlorella?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-benefits.html">Green Detox Q &amp; A - Benefits</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-green-detox-versus-other-detox-supplements.html">Green Detox Q &amp; A - Green Detox Versus Other Detox Supplements</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-green-detox-versus-other-greens-supplements.html">Green Detox Q &amp; A - Green Detox Versus Other Greens Supplements</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-are-toxins-a-real-threat.html">Green Detox Q &amp; A - Are "Toxins" a Real Threat?</a></p>
<p> </p></div>
</content>



    </entry>
    <entry>
        <title>Green Detox Q &amp; A - Are "Toxins" a Real Threat?</title>
        <link rel="alternate" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/green-detox-q-a-are-toxins-a-real-threat.html" />
        <link rel="replies" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/green-detox-q-a-are-toxins-a-real-threat.html" thr:count="0" />
        <id>tag:typepad.com,2003:post-6a00d8341cbdce53ef0153939cea1c970b</id>
        <published>2011-12-09T08:30:00-06:00</published>
        <updated>2011-12-09T08:30:00-06:00</updated>
        <summary>Q. Is there credible evidence that chronic low-level exposure to "toxins" is actually disrupting our metabolism and health? A. It's certainly true that the vague term "toxins" is often used as a scare tactic to market supplements of questionable efficacy....</summary>
        <author>
            <name>Integrated Supplements</name>
        </author>
        
        
<content type="xhtml" xml:lang="en-US" xml:base="http://integratedsupplements.typepad.com/integrated_supplements_bl/">
<div xmlns="http://www.w3.org/1999/xhtml"><p><span style="color: #005d86;"><strong> <a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0162fcf23974970d-pi" style="float: right;"><img alt="Blog_Icon_GreenDetox" class="asset  asset-image at-xid-6a00d8341cbdce53ef0162fcf23974970d" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0162fcf23974970d-250wi" style="width: 250px; margin: 0px 0px 5px 5px;" title="Blog_Icon_GreenDetox" /></a>Q. Is there credible evidence that chronic low-level exposure to "toxins" is actually disrupting our metabolism and health?</strong></span></p>
<p><span style="color: #005d86;"><strong>A.</strong></span> It's certainly true that the vague term "toxins" is often used  as a scare tactic to market supplements of questionable efficacy. As we've seen,  most so–called "detoxifying" supplements contain little more than herbal  laxatives, which simply aren't long–term solutions to reducing the body's toxic  burden.</p>
<p>But, evidence does suggest that our modern environment and diet  is exposing us to historically–unprecedented levels of toxic exposure.</p>
<p>For simplicity's sake, it's helpful to conceptualize toxins in  two main categories:</p>
<p>• Environmental chemicals</p>
<p>• Food–based toxins (including those produced either as a  function of cooking/processing or internally as a function of inefficient  digestion).</p>
<p>Objective measures of the body's burden of environmental  chemicals can be gleaned from The Centers for Disease Control and Prevention's  Fourth National Report on Human Exposure to Environmental Chemicals published in  2009:</p>
<p><a href="http://www.cdc.gov/exposurereport/pdf/FourthReport_ExecutiveSummary.pdf" target="_blank">Report Link – Fourth National Report on Human Exposure to  Environmental Chemicals</a></p>
<p>The researchers conducting the above report tested for the  presence of various environmental chemicals in blood and urine from a random  sample of participants taking part in the National Health and Nutrition  Examination Survey (NHANES). Particularly widespread exposure to the following  chemicals was noted:</p>
<p><strong>Polybrominated diphenyl ethers</strong> – fire  retardants used in various manufactured products, which accumulate in the  environment and in human fat tissue. One polybrominated diphenyl ether, BDE–47,  was found in the serum of nearly every subject tested.</p>
<p><strong>Bisphenol A (BPA)</strong> – a component of epoxy  resins and polycarbonates used to make lightweight plastics. BPA may cause  hormonal disruption and reproductive toxicity. More than 90% of the urine  samples tested by the CDC contained BPA.</p>
<p><strong>Perfluorooctanoic Acid (PFOA)</strong> – A  perfluorinated chemical associated with the manufacture of non–stick coatings  for cookware, food packaging, stain–resistant carpets, and carpet–cleaning  solutions, was found in the serum of nearly all subjects tested. The potential  toxicity of this chemical is subject of ongoing research.</p>
<p><strong>Perchlorate</strong> – a chemical which is both  naturally–occurring and man–made. Its industrial uses include the manufacture of  explosives, flares, and rocket fuel. High–level exposure to perchlorate is known  to impair thyroid function, and the consequences of chronic, low–level exposure  are currently under intense investigation. All participants tested exhibited  measurable levels of perchlorate in their urine.</p>
<p><strong>Mercury, Arsenic, Cadmium</strong> – Heavy metals such  as mercury, arsenic, and cadmium are naturally–occurring, but modern industrial  usage of these metals may lead to unprecedented levels of exposure. Research is  ongoing, but it's currently unknown what level of bodily exposure to these  metals can be deemed safe.</p>
<p>Numerous studies show that sea vegetables may possess the  unique ability to help rid the body of such harmful environmental chemicals.  Animal studies have shown Chlorella possesses the ability to aid in the  detoxification of the carcinogenic insecticide, chlordecone; the environmental  pollutant, dioxin; and the heavy metals, cadmium and lead:</p>
<p><a href="http://www.ncbi.nlm.nih.gov/pubmed/6202479" target="_blank">Study Link – Detoxification of Chlordecone Poisoned Rats with  Chlorella and Chlorella Derived Sporopollenin." </a></p>
<p><a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240248/" target="_blank">Study Link – Chlorophyll derived from Chlorella inhibits dioxin  absorption from the gastrointestinal tract and accelerates dioxin excretion in  rats.</a></p>
<p><a href="http://www.ncbi.nlm.nih.gov/pubmed/20016697" target="_blank">Study Link – Effect of Chlorella intake on Cadmium metabolism in  rats.</a></p>
<p><a href="http://www.ncbi.nlm.nih.gov/pubmed/12781705" target="_blank">Study Link – Protective effects of Chlorella vulgaris in  lead–exposed mice infected with Listeria monocytogenes.</a></p>
<p>Similarly, various seaweeds have been shown to aid in the  detoxification of chemicals such as dioxin a well as offering protection against  radioactive elements:</p>
<p><a href="http://www.ncbi.nlm.nih.gov/pubmed/5731951" target="_blank">Study Link – The role of marine plants on radiation  protection.</a></p>
<p><a href="http://www.ncbi.nlm.nih.gov/pubmed/11829667" target="_blank">Study Link – Seaweed accelerates the excretion of dioxin stored in  rats. </a></p>
<p><a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef015437708c5d970c-pi" style="float: right;"><img alt="Green DetoxJPG" class="asset  asset-image at-xid-6a00d8341cbdce53ef015437708c5d970c" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef015437708c5d970c-150wi" style="width: 150px; margin: 0px 0px 5px 5px;" title="Green DetoxJPG" /></a>As the above study illustrates, sea vegetables are even able to  increase the excretion of environmental chemicals which have been stored in the  body. These chemicals are continually complexed with bile and are excreted into  the intestines. A significant portion of the toxins in bile, however, aren't  eliminated, but reabsorbed into the body via a process known as enterohepatic  circulation. Nutritional strategies for detoxification often act, in large part,  by preventing the re–uptake of bile–borne toxins:</p>
<p><a href="http://www.ncbi.nlm.nih.gov/pubmed/17296488" target="_blank">Study Link – Enterohepatic circulation of organochlorine  compounds: a site for nutritional intervention.</a></p>
<p>Sea vegetables, for example, contain several substances (e.g.,  chlorophyll, dietary fibers, alginate) uniquely suited to prevent the absorption  and re–absorption of toxins from the gastrointestinal tract. Taken regularly,  the ingredients in Green Detox may be able to steadily reduce the body's burden  of toxic substances.*</p>
<p><a href="http://www.integratedsupplements.com/intsup/intsup0004.where_to_buy">Find a retailer for Green Detox and other Integrated Supplements Products</a></p>
<p><span style="color: #005d86;"> <strong>Related Posts:</strong></span></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-green-detox.html">Green Detox Q &amp; A - What is Green Detox?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-fucoidan.html">Green Detox Q &amp; A - What is Fucoidan?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-chlorella.html">Green Detox Q &amp; A - What is Chlorella?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-benefits.html">Green Detox Q &amp; A - Benefits</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-green-detox-versus-other-detox-supplements.html">Green Detox Q &amp; A - Green Detox Versus Other Detox Supplements</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-green-detox-versus-other-greens-supplements.html">Green Detox Q &amp; A - Green Detox Versus Other Greens Supplements</a></p>
<p> </p></div>
</content>



    </entry>
    <entry>
        <title>Green Detox Q &amp; A - Green Detox Versus Other "Greens" Supplements</title>
        <link rel="alternate" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/green-detox-q-a-green-detox-versus-other-greens-supplements.html" />
        <link rel="replies" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/green-detox-q-a-green-detox-versus-other-greens-supplements.html" thr:count="0" />
        <id>tag:typepad.com,2003:post-6a00d8341cbdce53ef0162fcf2308c970d</id>
        <published>2011-12-07T08:30:00-06:00</published>
        <updated>2011-12-07T08:30:00-06:00</updated>
        <summary>Q. How is Green Detox different from other "greens" supplements? A. "Greens" products are concentrated sources of whole–food nutrition – often targeted towards people who don't consume the recommended 3 to 5 servings of vegetables each day. These nutritional supplements...</summary>
        <author>
            <name>Integrated Supplements</name>
        </author>
        
        
<content type="xhtml" xml:lang="en-US" xml:base="http://integratedsupplements.typepad.com/integrated_supplements_bl/">
<div xmlns="http://www.w3.org/1999/xhtml"><p><span style="color: #005d86;"><strong> <a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0153939cb7cc970b-pi" style="float: right;"><img alt="Blog_Icon_GreenDetox" class="asset  asset-image at-xid-6a00d8341cbdce53ef0153939cb7cc970b" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0153939cb7cc970b-250wi" style="width: 250px; margin: 0px 0px 5px 5px;" title="Blog_Icon_GreenDetox" /></a>Q. How is Green Detox different from other "greens" supplements?</strong></span></p>
<p><span style="color: #005d86;"><strong>A.</strong></span> "Greens" products are concentrated sources of whole–food  nutrition – often targeted towards people who don't consume the recommended 3 to  5 servings of vegetables each day. These nutritional supplements contain a wide  array of concentrated vegetables, grasses, herbs, seeds, and other components.  Often, however, it seems that the makers of greens products place too much  emphasis on including dozens of different ingredients – even if the dose and  type of ingredients they use stand little chance of offering any health benefit.  More importantly, many greens formulas contain ingredients which simply aren't  optimal nutrition for humans.</p>
<p>For example, the following ingredients commonly found in greens  formulas, are ones which we feel are best avoided:</p>
<p><strong>Grasses</strong> (e.g., wheat grass, barley grass)</p>
<p>While cereal grasses such as wheat grass and barley grass are  concentrated sources of nutrients, humans may not possess the optimal digestive  system to extract these nutrients. Some greens products address this by using  powders made from cereal grass juices which may be easier to digest. But, even  still, we feel that cracked–cell chlorella is a far better choice for a greens  formula than any cereal grass. Not only is chlorella a more concentrated source  of nutrients and chlorophyll than cereal grasses, but processes which crack the  chlorella cell wall allow nutrients to be accessed by the human digestive system  while still offering the unique detoxicative benefits of chlorella's unique  dietary fiber.</p>
<p><strong>Seeds/Legumes</strong> (e.g., flax seeds, flax seed  meal, hemp seeds, chia seeds et al.)</p>
<p>While seeds contain nutrients necessary for germination, they  also contain substances which are mildly, but meaningfully, toxic. As a defense  mechanism, seeds are specifically designed to resist destruction by the  digestive systems of foraging animals. These defenses include not only a fibrous  outer shell which is resistant to digestion, but numerous anti–nutrients and  digestion–inhibiting substances inside the seed as well (e.g., phytates, trypsin  inhibitors, amylase inhibitors, cyanogenic glycosides, tannins and  phytoestrogens). Even polyunsaturated fatty acids in seeds can be counted among  these anti–nutrients, as these lipids inhibit digestion (especially when rancid  – as would be a likely occurrence in any greens product). Ultimately, some of  nature's most potent food–based toxins and anti–nutrients are found in seeds,  making their inclusion in nutritional products ill–advised.</p>
<p><strong>Vegetables which contain anti–nutrients</strong></p>
<p>In addition to important vitamins and minerals, many vegetables  contain anti–nutrients – substances which can inhibit digestion and the  absorption of nutrients. Spinach, for example is nutrient–dense, but also  contains oxalic acid which may impair mineral absorption and digestion.  Vegetables of the brassica family (e.g., cabbage, brussel sprouts, kale) contain  goitrogens which are known to inhibit thyroid function. Alfalfa sprouts contain  canavanine, analog of the amino acid, arginine, which has been associated with  hemolytic anemia and immune dysfunction:</p>
<p><a href="http://www.ncbi.nlm.nih.gov/pubmed/3155617" target="_blank">Study Link – Effects of L–canavanine on T cells may explain the  induction of systemic lupus erythematosus by alfalfa.</a></p>
<p>Traditional cooking methods often served to maximize the  nutritional content of vegetables, while minimizing such anti–nutritional  factors. However, the effects of consuming dried, concentrated versions of these  vegetables (and the anti–nutrients they contain) - as would be found in greens  formulas – are simply unknown. Depending upon the formulation, some greens  formulas may expose users to far greater risk of toxicity than the consumption  of food vegetables.</p>
<p><a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef015437707a3a970c-pi" style="float: right;"><img alt="Green DetoxJPG" class="asset  asset-image at-xid-6a00d8341cbdce53ef015437707a3a970c" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef015437707a3a970c-150wi" style="width: 150px; margin: 0px 0px 5px 5px;" title="Green DetoxJPG" /></a>Not only are sea vegetables likely to be far more concentrated  sources of nutrition than land–based vegetables, sea vegetables are also likely  to contain far fewer anti–nutrients than land–based vegetables as well. In  addition, certain sea vegetables contain health–promoting substances (e.g.,  fucoidan) which are simply non–existent in land–based vegetables. Sea vegetables  are also almost completely absent from the diet of people in the U.S. and many  parts of the industrialized Western world. All of these factors make  carefully–selected sea vegetables uniquely suited for use in dietary  supplements.</p>
<p><a href="http://www.integratedsupplements.com/intsup/intsup0004.where_to_buy">Find a retailer for Green Detox and other Integrated Supplements Products</a></p>
<p><span style="color: #005d86;"> <strong>Related Posts:</strong></span></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-green-detox.html">Green Detox Q &amp; A - What is Green Detox?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-fucoidan.html">Green Detox Q &amp; A - What is Fucoidan?</a><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-chlorella.html" /></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-chlorella.html">Green Detox Q &amp; A - What is Chlorella?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-benefits.html">Green Detox Q &amp; A - Benefits</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-green-detox-versus-other-detox-supplements.html">Green Detox Q &amp; A - Green Detox Versus Other Detox Supplements</a></p>
<p> </p></div>
</content>



    </entry>
    <entry>
        <title>Green Detox Q &amp; A - Green Detox Versus Other Detox Supplements</title>
        <link rel="alternate" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/green-detox-q-a-green-detox-versus-other-detox-supplements.html" />
        <link rel="replies" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/green-detox-q-a-green-detox-versus-other-detox-supplements.html" thr:count="0" />
        <id>tag:typepad.com,2003:post-6a00d8341cbdce53ef015437706b16970c</id>
        <published>2011-12-05T08:30:00-06:00</published>
        <updated>2011-12-05T08:30:00-06:00</updated>
        <summary>Q. How is Green Detox different from other detox supplements? A. Many supplements marketed for body detoxification contain harsh laxative herbs such as cascara sagrada or senna as their main ingredients. Though supporting healthy digestive function and elimination are important...</summary>
        <author>
            <name>Integrated Supplements</name>
        </author>
        
        
<content type="xhtml" xml:lang="en-US" xml:base="http://integratedsupplements.typepad.com/integrated_supplements_bl/">
<div xmlns="http://www.w3.org/1999/xhtml"><p><span style="color: #005d86;"><strong> <a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef015437705b06970c-pi" style="float: right;"><img alt="Blog_Icon_GreenDetox" class="asset  asset-image at-xid-6a00d8341cbdce53ef015437705b06970c" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef015437705b06970c-250wi" style="width: 250px; margin: 0px 0px 5px 5px;" title="Blog_Icon_GreenDetox" /></a>Q. How is Green Detox different from other detox supplements?</strong></span></p>
<p><span style="color: #005d86;"><strong>A.</strong></span> Many supplements marketed for body detoxification contain harsh  laxative herbs such as cascara sagrada or senna as their main ingredients.  Though supporting healthy digestive function and elimination are important for  detoxification, the use of harsh laxative herbs is not the best way to  accomplish this. Because of their potential to cause side effects and  dependency, these herbs should not be taken for extended periods of time, if at  all. In fact, rather than being detoxifying, herbs such as cascara sagrada pose  a toxicity risk all their own:</p>
<p><a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504026/" target="_blank">Study Link – Botanical Dietary Supplements Gone Bad.</a></p>
<p>Quote from the above study:</p>
<blockquote>
<p><span style="color: #666666;"><em>The chronic use of Cascara sagrada  involves several risks. Besides cramp like pains in the gastrointestinal tract,  chronic use disturbs the electrolyte balance, especially potassium deficiency,  causing a circulus vitiosus and a dependency on purgative dietary supplements.  In addition, several studies reported genotoxic and mutagenic effects in vitro  and in vivo for emodin and its derivatives causing them to be classified as  prospective carcinogens. Cascara sagrada products are still advertised as  slimming or detoxification products; however, considering the potential side  effects after chronic use, the intake of this herb for these indications should  be restrained.</em></span><em> </em></p>
</blockquote>
<p>Other detox supplements often contain mixtures of herbal  components such as milk thistle, red clover, or green tea extract. But, though  many of the ingredients in these herbal mixtures may have some therapeutic value  for some people in some situations, there's little reason to believe that these  haphazard mixtures of herbs will truly support the body's detoxification  mechanisms in the long–term.</p>
<p>Many supposedly "detoxifying" herbs may transiently stimulate  liver function, or the activity of detoxifying enzymes in the gastrointestinal  tract – but they also have the potential to do harm with continued use. Red  clover, for example, contains potent phytoestrogens – substances that could  ultimately add to the body's toxic/estrogenic burden when consumed regularly or  in excess. Similarly, high intakes of green tea extracts have also been shown to  cause liver damage:</p>
<p><a href="http://www.ncbi.nlm.nih.gov/pubmed/19198822" target="_blank">Study Link – Hepatotoxicity from green tea: a review of the  literature and two unpublished cases.</a></p>
<p>Quote from the above study:</p>
<blockquote>
<p><span style="color: #666666;"><em>Our analysis of the published case  reports suggests a causal association between green tea and liver damage. The  hepatotoxicity is probably due to (–)–epigallocatechin gallate or its  metabolites which, under particular conditions related to the patient's  metabolism, can induce oxidative stress in the  liver.</em></span><em> </em></p>
</blockquote>
<p><a href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0162fcf20759970d-pi" style="float: right;"><img alt="Green DetoxJPG" class="asset  asset-image at-xid-6a00d8341cbdce53ef0162fcf20759970d" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef0162fcf20759970d-150wi" style="width: 150px; margin: 0px 0px 5px 5px;" title="Green DetoxJPG" /></a>But Green Detox is different – it doesn't contain harsh  laxatives or herbs which tax detoxification pathways. The cleansing properties  of green detox are much gentler, and are largely attributable to two factors:</p>
<p>• Unique dietary fibers and polysaccharides uniquely found in  chlorella and seaweeds.</p>
<p>• Particularly high concentrations of the detoxifying green  pigment, chlorophyll.</p>
<p>Dietary fibers and chlorophyll are essential for proper body  detoxification, and sea vegetables are among the most concentrated sources of  these substances. With the unique nutrition they offer, it's no wonder that sea  vegetables/seaweeds have been staples in the diet of various cultures for  centuries. As a whole–food nutritional supplement which concentrates the  nutritional value of such foods, Green Detox is ideal for everyday use.</p>
<p><a href="http://www.integratedsupplements.com/intsup/intsup0004.where_to_buy">Find a retailer for Green Detox and other Integrated Supplements Products</a></p>
<p><span style="color: #005d86;"> <strong>Related Posts:</strong></span></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-green-detox.html">Green Detox Q &amp; A - What is Green Detox?</a> <br /> <a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-fucoidan.html" /></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-fucoidan.html">Green Detox Q &amp; A - What is Fucoidan?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-what-is-chlorella.html">Green Detox Q &amp; A - What is Chlorella?</a></p>
<p><a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/11/green-detox-q-a-benefits.html">Green Detox Q &amp; A - Benefits</a></p>
<p> </p></div>
</content>



    </entry>
    <entry>
        <title>A Diet For Long-Term Weight Control and Optimal Health Part 7 - Healthy Intakes of Omega-3 Fatty Acids</title>
        <link rel="alternate" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/a-diet-for-long-term-weight-control-and-optimal-health-part-7-healthy-intakes-of-omega-3-fatty-acids.html" />
        <link rel="replies" type="text/html" href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/12/a-diet-for-long-term-weight-control-and-optimal-health-part-7-healthy-intakes-of-omega-3-fatty-acids.html" thr:count="0" />
        <id>tag:typepad.com,2003:post-6a00d8341cbdce53ef015393f89ae9970b</id>
        <published>2011-12-03T16:26:47-06:00</published>
        <updated>2011-12-03T17:09:12-06:00</updated>
        <summary>Popular health and nutrition articles often posit the essential omega–6 and omega–3 fatty acids simplistically as the "good fats." Rarely, however, is any mention given to the actual amounts and ratios of these lipids required for good health. As we've...</summary>
        <author>
            <name>Integrated Supplements</name>
        </author>
        
        
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&lt;div xmlns="http://www.w3.org/1999/xhtml"&gt;&lt;p class="style20"&gt;&lt;a style="float: right;" href="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef015393f85cff970b-pi"&gt;&lt;img class="asset  asset-image at-xid-6a00d8341cbdce53ef015393f85cff970b" style="width: 250px; margin: 0px 0px 5px 5px;" title="HeaderPic201201" src="http://integratedsupplements.typepad.com/.a/6a00d8341cbdce53ef015393f85cff970b-250wi" alt="HeaderPic201201" /&gt;&lt;/a&gt;Popular health and nutrition articles often posit the  essential omega–6 and omega–3 fatty acids simplistically as the "good  fats."&amp;nbsp; Rarely, however, is any mention  given to the actual amounts and ratios of these lipids required for good  health.&amp;nbsp; As we've seen in previous  editions of the Integrated Supplements Newsletter, a gross excess of the  omega–6 essential fatty acid, linoleic acid in the modern diet may be a major  contributing factor to obesity and related chronic diseases such as diabetes, cancer,  and heart disease.&amp;nbsp; For all practical  purposes, therefore, it's clear that linoleic acid is anything but a "good  fat."&lt;/p&gt;
&lt;p class="style20"&gt;Similar confusion currently surrounds the  omega–3 fatty acids.&amp;nbsp; As a delicate  balance exists between omega–6 and omega–3 fatty acids, studies have begun to  find that the ratio of the two in the diet may be an important factor in  mediating inflammation and the development of chronic disease.&amp;nbsp; The excess of omega–6 linoleic acid in our  modern diet has led many researchers and product marketers to advocate  increased intakes of the omega–3 fatty acids to balance the ratio of the two  classes of lipids.&amp;nbsp; As omega–3 fatty  acids have garnered a steadily–increasing amount of mainstream acceptance,  numerous sources of omega–3 fatty acids have been aggressively marketed in  recent years, including fish oil, flax oil (and flaxseeds), krill oil, hemp  oil, and many others.&lt;/p&gt;
&lt;p class="style20"&gt;But, with omega–3 supplements, we again  find that the recommendations of the supplement marketers leave much to be  desired.&amp;nbsp; Many people currently consuming  omega–3 fatty acid supplements aren't emulating the fatty acid intakes of  healthy cultures, and are instead unwittingly consuming fatty acid intakes with  no historical precedent, and with no scientific backing.&amp;nbsp; The dangers of excess omega–3 consumption  have now become a very real concern for millions of people who have been  influenced by the widespread advice of health authorities and product sellers.&lt;/p&gt;
&lt;p class="style20"&gt;What's desperately needed is rational  perspective on the amounts and ratios of fatty acids which are likely to offer  protection against metabolic disruption and chronic disease.&amp;nbsp; As it turns out, the optimal dose of omega–3  fatty acids is far lower than is often implied by supplement marketers.&amp;nbsp; Supplements of omega–3 fatty acids are almost  never advisable, and, in fact, common supplemental doses of omega–3 fatty acids  are likely to be harmful when consumed over extended periods of time.&amp;nbsp;&lt;/p&gt;
&lt;p class="style20"&gt;An excess of omega–3 fatty acids has been  shown to result in profound suppression of the immune system which may lead to  increased incidence of infection in the short term, and possibly the  development of autoimmune disorders and even cancer in the longer–term.&amp;nbsp; In addition, the tendency of fragile omega–3  fatty acids to spontaneously (i.e., non–enzymatically) oxidize is partly  responsible for their potential toxicity.&amp;nbsp;  Oxidized metabolites of omega–3 fatty acids may cause widespread  metabolic disruption as they impair metabolism on a fundamental cellular  level.&amp;nbsp; Inhibition of thyroid function,  weight gain, accelerated skin aging, digestive disturbances, mood disorders,  joint disorders, and liver damage are just a few of the potential detriments of  omega–3 excess.&amp;nbsp;&lt;/p&gt;
&lt;p class="style20"&gt;As is so often the case in the marketing  of nutritional supplements, the potential benefits of omega–3 fatty acids have  been wildly overstated, while little to no mention has been made of the  potential risks.&lt;/p&gt;
&lt;p class="style21"&gt;&lt;span style="color: #005d86;"&gt;&lt;strong&gt; &lt;em&gt;A Brief Overview of Essential Fatty Acid Metabolism&lt;/em&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p class="style20"&gt;Omega–6 linoleic acid and omega–3  alpha–linolenic acid are considered essential to human nutrition.&amp;nbsp; These essential fatty acids (and the fatty  acids derived from them) are involved in metabolic cascades which produce  various inflammatory (and anti–inflammatory) chemicals.&amp;nbsp; Linoleic acid is metabolized largely into the  inflammatory mediator, arachidonic acid, while alpha–linolenic acid is  (ideally) metabolized largely into the anti–inflammatory long–chain omega–3  fatty acids such as EPA and DHA.&lt;/p&gt;
&lt;p class="style20"&gt;The term: "essential," however, can be a  bit misleading when used to describe nutrients like the essential fatty  acids.&amp;nbsp; First off, linoleic and  alpha–linolenic acids are merely parent chemicals for fatty acids which can  easily be consumed through food.&amp;nbsp; Meats,  eggs, and dairy, for example, are well–known sources of arachidonic acid, while  seafood is the richest source of EPA and DHA.&amp;nbsp;  Consuming these "ready–made" fatty acid metabolites is likely to  significantly reduce the requirements for their parent chemicals.&amp;nbsp; In addition, an outright deficiency of either  essential fatty acid is nearly impossible to achieve on any whole–food  diet.&amp;nbsp; Only in laboratory and hospital  settings have such deficiencies manifested, owing to poorly–constructed  artificial diets.&amp;nbsp;&lt;/p&gt;
&lt;p class="style20"&gt;But, though outright essential–fatty–acid  deficiency is rare, imbalances between the omega–6 and omega–3 fatty acids are  common.&amp;nbsp;&amp;nbsp;&lt;/p&gt;
&lt;p class="style20"&gt;The metabolism of omega–6 linoleic acid  into arachadonic acid, and omega–3 alpha–linolenic acid into the long–chain  omega–3s (e.g., EPA and DHA), both require some of the same metabolic  enzymes.&amp;nbsp; This is why, as we've seen in  previous Integrated Supplements Newsletters, an excess of omega–6 linoleic acid  in the modern diet can dramatically interfere with the production of long–chain  omega–3s, and their incorporation into tissues.&lt;/p&gt;
&lt;p class="style5"&gt;&lt;img src="http://www.integratedsupplements.com/email/images/FAMetabolism.jpg" border="0" alt="" width="450" height="500" /&gt;&lt;/p&gt;
&lt;p class="style20"&gt;The efficient incorporation of long–chain  omega–3 fatty acids (e.g., DHA) into tissues is thought to be required for the  health benefits of omega–3s to manifest.&amp;nbsp;  The question then becomes: how do we ensure that omega–3s are  metabolized safely and efficiently so as to optimize tissue levels of  long–chain omega–3s?&amp;nbsp; Consuming  additional alpha–linolenic acid (e.g., plant–based omega–3 sources such as oils  from soybeans, canola, flax, hemp, chia, &lt;em&gt;et al&lt;/em&gt;.) doesn't seem to be the  answer – especially if the diet contains excess linoleic acid.&amp;nbsp; Alpha–linolenic acid simply doesn't seem to  be metabolized into the long–chain omega–3s efficiently in the presence of  linoleic acid:&lt;/p&gt;
&lt;p class="style20"&gt;&lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/9637947/" target="_blank"&gt;Study Link – Can adults adequately convert  alpha–linolenic acid (18:3n–3) to eicosapentaenoic acid (20:5n–3) and  docosahexaenoic acid (22:6n–3)?&lt;/a&gt;&lt;/p&gt;
&lt;p class="style20"&gt;Quote from the  above study:&lt;/p&gt;
&lt;blockquote&gt;
&lt;p class="style20"&gt;&lt;span style="color: #666666;"&gt;&lt;em&gt;The use of ALA labelled with  radioisotopes suggested that with a background diet high in saturated fat  conversion to long–chain metabolites is approximately 6% for EPA and 3.8% for  DHA. With a diet rich in n–6 PUFA, conversion is reduced by 40 to 50%.&lt;/em&gt;&lt;/span&gt;&lt;/p&gt;
&lt;/blockquote&gt;
&lt;p class="style20"&gt;Knowing this, it probably makes sense to  consume some long–chain omega–3s from seafood, but consuming significant  (supplemental) amounts of additional long–chain omega–3s from fish/marine oils,  is a practice which should be questioned.&amp;nbsp;  The long–chain omega–3s are very chemically fragile, and are well–documented  to undergo spontaneous oxidation in the body when consumed in excess.&amp;nbsp; Worse yet, adding fish oils (and the like) to  a diet high in linoleic acid will only increase overall polyunsaturated fatty  acid (PUFA) intake to one likely to cause widespread oxidative damage over  time.&lt;/p&gt;
&lt;p class="style20"&gt;This is why we've previously advocated  that the linoleic acid content of the diet (and overall PUFA intake) be kept  low (~2% of calories).&amp;nbsp; Not only does a  low linoleic acid intake facilitate the incorporation of long–chain omega–3s  into tissue, but low overall levels of PUFA make oxidative damage of PUFA less  likely (with low linoleic acid intake, only trace amounts of omega–3 fatty  acids are needed to optimize tissue levels of long–chain omega–3s, so lipid  peroxidation is not a major concern).&lt;/p&gt;
&lt;p class="style21"&gt;&lt;span style="color: #005d86;"&gt;&lt;strong&gt; &lt;em&gt;Healthy Intakes of Omega–3 and Omega–6 Fatty Acids&lt;/em&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p class="style20"&gt;Where overt essential fatty acid  deficiency is rare, the recommendations of public health authorities for  essential–fatty–acids are geared towards achieving optimal tissue levels  resulting in reduced risk of chronic disease.&amp;nbsp;  Many researchers have noted a correlation between the level of  long–chain (e.g., EPA, DHA) omega–3 fatty acids in tissue, and protection from  various chronic and/or degenerative disorders.&amp;nbsp;  Achieving healthy tissue levels of omega–3, however, is only partly  determined by dietary omega–3 intake.&amp;nbsp;  Because the metabolism of the two classes of fatty acids is so  intertwined, a healthy intake of omega–3 fatty acids simply cannot be derived  without also looking at the background level of omega–6 fats in the diet.&amp;nbsp;&lt;/p&gt;
&lt;p class="style20"&gt;Studies have found that when the level of  omega–6 fats in the diet is low, the level of omega–3s needed to ensure healthy  tissue omega–3 levels is low as well.&amp;nbsp;  When the level of omega–6 fats in the diet is high (as it is in the  United States and many other industrialized countries), the level of omega–3s  needed to ensure healthy tissue levels of omega–3s is commensurately high.&lt;/p&gt;
&lt;p class="style20"&gt;Along these lines, researchers have  calculated the dietary levels of long–chain omega–3s which would be needed to  ensure what they believe to be healthy tissue levels of these fatty acids.&amp;nbsp; In countries with low linoleic acid intake,  healthy omega–3 intakes would be miniscule.&amp;nbsp;  In the Philippines, for example, where a mere 0.8% of calories come from  linoleic acid, a paltry 278 milligrams of long–chain omega–3s per day would be  sufficient to achieve what were deemed to be healthy omega–3 tissue levels.&lt;/p&gt;
&lt;p class="style20"&gt;By contrast, in the United States, where  7% to 9% of dietary calories come from linoleic acid, 3,667 milligrams of  long–chain omega–3s would be necessary to achieve healthy tissue levels:&lt;/p&gt;
&lt;p class="style20"&gt;&lt;a href="http://www.ajcn.org/content/83/6/S1483.short" target="_blank"&gt;Study Link – Healthy intakes of n–3 and n–6  fatty acids: estimations considering worldwide diversity.&lt;/a&gt;&lt;/p&gt;
&lt;p class="style20"&gt;Quote from the  above study:&lt;/p&gt;
&lt;blockquote&gt;
&lt;p class="style20"&gt;&lt;span style="color: #666666;"&gt;&lt;em&gt;n–3 LCFA intakes needed to meet a  tissue target representative of Japan (60% n–3 in LCFA) ranged from 278 mg/d  (Philippines, with intakes of 0.8% of energy as linoleate, 0.08% of energy as &lt;/em&gt;&lt;em&gt;a–&lt;/em&gt;&lt;em&gt;linolenate, and 0.06% of energy as arachidonic acid)  to 3667 mg/d (United States, with 8.91% of energy as linoleate, 1.06% of energy  as &lt;/em&gt;&lt;em&gt;a– &lt;/em&gt;&lt;em&gt;linolenate, and 0.08% of  energy as arachidonic acid). &lt;/em&gt;&lt;/span&gt;&lt;/p&gt;
&lt;/blockquote&gt;
&lt;p class="style20"&gt;The safety of such high doses of EPA and  DHA is questionable, however.&amp;nbsp; Even the  US FDA has stated that the combined dose of EPA and DHA from supplements should  not exceed 3 grams (3,000 mg) per day.&lt;/p&gt;
&lt;p class="style20"&gt;Importantly, the researchers of the above  study noted that the long chain omega–3 content needed to ensure healthy tissue  levels in Americans could be reduced to &lt;strong&gt;&lt;em&gt;one–tenth&lt;/em&gt;&lt;/strong&gt; of this dose if  intake of linoleic acid was lowered.&amp;nbsp;  Clearly, then, the ideal answer is to lower linoleic acid intakes – &lt;strong&gt;&lt;em&gt;not&lt;/em&gt;&lt;/strong&gt; to dramatically increase intakes of EPA and DHA:&lt;/p&gt;
&lt;p class="style20"&gt;Quote from the  above study:&lt;/p&gt;
&lt;blockquote&gt;
&lt;p class="style20"&gt;&lt;span style="color: #666666;"&gt;&lt;em&gt;This  allowance for n–3 LCFAs can likely be reduced to one–tenth of that amount by  consuming fewer n–6 fats.&lt;/em&gt;&lt;/span&gt;&lt;/p&gt;
&lt;/blockquote&gt;
&lt;p class="style20"&gt;Again, this fact is significant, as the  omega–6 and, to a greater extent omega–3 fatty acids are chemically  fragile.&amp;nbsp; Consuming high amounts of both  could lead to various forms of metabolic disruption including immune  dysfunction, premature aging (most visibly premature aging of the skin),  digestive and gastrointestinal disturbances, bleeding disorders, reduced blood  sugar control, depression, and even cancer.&amp;nbsp;  The potential for these long–term effects indicates that there's more to  essential fatty acid nutrition than just achieving tissue omega–3 levels which  happen to correspond to those of healthy cultures.&amp;nbsp; Those advocating omega–3 supplementation  often fail to make any mention of the importance of lowering the omega–6  (especially linoleic acid) content of the diet to avoid an overall excess of  PUFA consumption.&lt;/p&gt;
&lt;p class="style21"&gt;&lt;span style="color: #005d86;"&gt;&lt;strong&gt; &lt;em&gt;Which Diet Should We Emulate?&lt;/em&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p class="style20"&gt;The researchers conducting the above study  used Japanese tissue levels of long–chain omega–3s as the benchmark for healthy  intakes.&amp;nbsp; They found that the Japanese  intake of long–chain omega–3s (~750 mg per day combined of EPA and DHA) would  offer 98% of the worldwide population protection against numerous diet–related  diseases.&amp;nbsp; But even the Japanese diet may  be less–than–optimal when it comes to fatty acid intake.&amp;nbsp; Though the health benefits of the Japanese  diet are largely attributed to the regular intake of seafood rich in long–chain  omega–3s, researchers have provided convincing evidence that the linoleic acid  content of the Japanese diet (though significantly lower than that of the  American diet) may still be too high for optimal health.&lt;/p&gt;
&lt;p class="style20"&gt;To improve the health of the Japanese  population, The Japan Society for Lipid Nutrition has recently recommended that  linoleic acid intake be reduced.&amp;nbsp; The  authors of the scholarly article below go so far as to state that the  widely–touted benefits of omega–3 fatty acids can be alternately interpreted as  illustrative of the effects of linoleic acid excess – a fact which is often  conveniently ignored by the sellers of omega–3 supplements:&lt;/p&gt;
&lt;p class="style20"&gt;&lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/14579687" target="_blank"&gt;Article Link – The Japan Society for Lipid  Nutrition recommends to reduce the intake of linoleic acid. A review and  critique of the scientific evidence.&lt;/a&gt;&lt;/p&gt;
&lt;p class="style20"&gt;Quote from the  above study:&lt;/p&gt;
&lt;blockquote&gt;
&lt;p class="style20"&gt;&lt;span style="color: #666666;"&gt;&lt;em&gt;There are quite a few mechanisms of  action of omega–3 fatty acids, but the competition between the omega–6 and  omega–3 fatty acids at steps of elongation, desaturation, esterification into  phospholipids, their release, conversion to eicosanoids (lipid mediators) and  at their receptors is the major theme that explains why omega–3 fatty acids are  necessary for the prevention of CHD [coronary heart disease] and other chronic  diseases.&amp;nbsp; Accepting the usefulness of  omega–3 fatty acids is nearly equal to admitting the risk of excessive LA [linoleic  acid] intake. &lt;/em&gt;&lt;/span&gt;&lt;/p&gt;
&lt;/blockquote&gt;
&lt;p class="style20"&gt;The authors go on to say that, for those  who eat fish regularly (as the Japanese generally do) a healthy intake of  linoleic acid may be below 3% of calories.&amp;nbsp;  The authors found no evidence to recommend that the Japanese increase  their omega–3 consumption.&lt;/p&gt;
&lt;p class="style20"&gt;For all intents and purposes, therefore,  the Japanese intake of long–chain omega–3 fatty acids (~ 750 mg per day) likely  represents the &lt;strong&gt;&lt;em&gt;upper limit&lt;/em&gt;&lt;/strong&gt; of what healthy cultures have been  shown to consume.&amp;nbsp; Even this amount, however,  may be higher than is optimal.&amp;nbsp; Because  of the metabolic instability of omega–3s, there's clearly a limit on how many  can be consumed without doing harm.&amp;nbsp; The  few cultures consuming higher amounts of long–chain omega–3s than the Japanese  simply don't seem to experience additional health benefits as a result.&amp;nbsp; Likely because of their high intake of  omega–3 lipids, Inuit cultures, for example, are known to exhibit bleeding  disorders, and premature signs of aging:&lt;/p&gt;
&lt;p class="style20"&gt;&lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/7438807" target="_blank"&gt;Study Link – The bleeding tendency in Greenland  Eskimos.&lt;/a&gt;&lt;/p&gt;
&lt;p class="style20"&gt;And in controlled trials incorporating  omega–3 rich fish oils, higher omega–3 doses generally compromise the  beneficial effects instead of enhancing them.&lt;/p&gt;
&lt;p class="style20"&gt;Mediterranean–style diets have been  associated with reduced risk of cardiovascular disease and reduced rates of  all–cause mortality.&amp;nbsp; Though the omega–3  content of the Mediterranean diet may be higher than that of the standard  American diet, it may be their low level of linoleic acid which is a more  important health–promoting factor.&lt;/p&gt;
&lt;p class="style20"&gt;The Lyon Diet Heart Study – one of the  most successful studies ever conducted on the association between diet and  cardiovascular disease – found that the reduction in linoleic acid was an  essential part of the Mediterranean diet's success:&lt;/p&gt;
&lt;p class="style20"&gt;&lt;a href="http://circ.ahajournals.org/cgi/content/full/99/6/733" target="_blank"&gt;Study Link – Dietary Prevention of Coronary  Heart Disease The Lyon Diet Heart Study.&lt;/a&gt;&lt;/p&gt;
&lt;p class="style20"&gt;Quote from the  above study:&lt;/p&gt;
&lt;blockquote&gt;
&lt;p class="style20"&gt;&lt;span style="color: #666666;"&gt;&lt;em&gt;...only the trials that also lowered  intake of n–6 PUFAs and increased n–3 fatty acids successfully  lowered cardiovascular and all–cause mortality in the experimental  cohort.&lt;/em&gt;&lt;/span&gt;&lt;/p&gt;
&lt;/blockquote&gt;
&lt;p class="style20"&gt;The fact that the  Lyon Diet Heart Study employed the use of parent alpha–linolenic acid from  canola oil (and not long–chain omega–3s as would be found in fish oil) is  further evidence that excess linoleic acid is likely to be a more important  contributor to diet–related disease than the amount or type of omega–3s.&lt;/p&gt;
&lt;p class="style20"&gt;In all likelihood, those seeking to  prevent diet–related disorders by altering their fatty acid intake will be well  served to reduce their linoleic acid intake to below 2% of daily calories.&amp;nbsp; With this low linoleic acid intake, optimal  intakes of EPA and DHA will likely be significantly lower than the average  intake in Japan.&amp;nbsp; But, as the majority of  the industrialized world is likely to consume excess linoleic acid, the formal  omega–3 recommendations of several countries, as well as the World Health  Organization and North Atlantic Treaty Organization may therefore be slightly  high.&amp;nbsp; These organizations generally recommend  between 300 mg and 500 mg of total EPA and DHA per day.&amp;nbsp; This amount is roughly in line with the  American Heart Association's recommendation to consume 1 to 2 fish meals per  week.&amp;nbsp;&lt;/p&gt;
&lt;p class="style20"&gt;Although 300 mg – 500 mg of EPA and DHA  may be slightly higher than optimal on a diet low in linoleic acid, this intake  is still reasonable and, in all likelihood, safe.&amp;nbsp; Many of those who take omega–3 supplements,  however, may be consuming far greater (and potentially unsafe) amounts of  omega–3 fatty acids.&amp;nbsp; It's not entirely  uncommon to find fish oils and related sources of omega–3s recommended in doses  of multiple teaspoons per day – doses which not a shred of long–term scientific  evidence actually supports.&amp;nbsp; A single  teaspoon (or 5 capsules) of standard fish oil for example, will contain  approximately 1300 mg of combined EPA and DHA – an amount almost &lt;strong&gt;&lt;em&gt;twice&lt;/em&gt;&lt;/strong&gt; that of the average Japanese intake per day.&amp;nbsp;  Add to this the EPA and DHA in the diet, and many supplement takers are  sure to be consuming problematic amounts of long–chain omega–3s.&lt;/p&gt;
&lt;p class="style21"&gt;&lt;span style="color: #005d86;"&gt;&lt;strong&gt; &lt;em&gt;Alpha–Linolenic Acid – What Omega–3  Deficiency?&lt;/em&gt;&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p class="style20"&gt;In addition, those consuming plant–based  sources of omega–3 alpha–linolenic acid (e.g., flax oil, hemp oil) may not only  be consuming a relatively inefficient source of omega–3, but may also be adding  to their burden of linoleic acid as these plant–based sources invariably  contain significant amounts of it.&lt;/p&gt;
&lt;p class="style20"&gt;As such, reviews of the literature have  found the health benefits of omega–3 alpha–linolenic acid to be inconsistent at  best – likely because many variables exist which may interfere with the proper  conversion of alpha–linolenic acid into the long–chain omega–3s:&lt;/p&gt;
&lt;p class="style20"&gt;&lt;a href="http://www.ajcn.org/content/84/1/5.full" target="_blank"&gt;Study Link – n–3 Fatty acids from fish or fish  oil supplements, but not alpha–linolenic acid, benefit cardiovascular outcomes  in primary– and secondary prevention studies: a systematic review.&lt;/a&gt;&lt;/p&gt;
&lt;p class="style20"&gt;Quote from the  above study:&lt;/p&gt;
&lt;blockquote&gt;
&lt;p class="style20"&gt;&lt;span style="color: #666666;"&gt;&lt;em&gt;Evidence suggests that increased  consumption of n–3 FAs from fish or fish–oil supplements, but not of &lt;/em&gt;&lt;em&gt;a–&lt;/em&gt;&lt;em&gt;linolenic acid, reduces the rates of all–cause  mortality, cardiac and sudden death, and possibly stroke.&lt;/em&gt;&lt;/span&gt;&lt;/p&gt;
&lt;/blockquote&gt;
&lt;p class="style20"&gt;Those who attribute modern diet–related  disorders to an omega–3 deficiency should carefully investigate the changes in  the omega–3 content of the American diet throughout the 20th  Century.&amp;nbsp; Largely due to increases in the  consumption of soybean and canola oil, the omega–3 content of the American diet  actually &lt;strong&gt;&lt;em&gt;increased&lt;/em&gt;&lt;/strong&gt; significantly between 1909 and 1999.&amp;nbsp;&amp;nbsp; Depending upon the type of calculations  used, the omega–3 alpha–linolenic acid content of the diet during this time  increased from 0.39% to up to 0.72% of calories:&lt;/p&gt;
&lt;p class="style20"&gt;&lt;a href="http://www.ncbi.nlm.nih.gov/pubmed/21367944" target="_blank"&gt;Study Link – Changes in consumption of omega–3  and omega–6 fatty acids in the United States during the 20th century.&lt;/a&gt;&lt;/p&gt;
&lt;p class="style20"&gt;The above study notes, however, that the  concomitant increase in linoleic acid consumption during this time has served  to interfere with the metabolism and incorporation of omega–3 fatty acids in  tissues:&lt;/p&gt;
&lt;p class="style20"&gt;Quote from the  above study:&lt;/p&gt;
&lt;blockquote&gt;
&lt;p class="style20"&gt;&lt;span style="color: #666666;"&gt;&lt;em&gt;The estimated per capita consumption  of soybean oil increased &amp;gt;1000–fold from 1909 to 1999. The availability of  linoleic acid (LA) increased from 2.79% to 7.21% of energy... The apparent  increased consumption of LA, which was primarily from soybean oil, has likely  decreased tissue concentrations of EPA and DHA during the 20th century.&lt;/em&gt;&lt;/span&gt;&lt;/p&gt;
&lt;/blockquote&gt;
&lt;p class="style20"&gt;Sellers of plant–based omega–3 supplements  such as flax oil and hemp oil should address the question: If adding  alpha–linolenic acid to the diet were beneficial in correcting modern  diet–related disorders, why did these disorders become epidemic during the time  when the American public did just that?&amp;nbsp;  The only honest stance, of course, is that we don't need more omega–3  alpha–linolenic acid in our diet – we simply need to dramatically reduce the  diet's level of omega–6 linoleic acid.&amp;nbsp;  This simple solution is hard to come by, however, as there's no money to  be made by telling people what to avoid.&amp;nbsp;&lt;/p&gt;
&lt;p class="style20"&gt;From the research that exists, we yet  again find reason to believe that an excess of linoleic acid is the primary  lipid–related contributor to modern chronic diseases.&amp;nbsp; It's unlikely, therefore, that omega–3 fatty  acids will function optimally unless linoleic acid levels are lowered.&amp;nbsp; Simply adding omega–3 fatty acids to the diet  is a far–riskier practice than many people imagine, and in the next Integrated  Supplements Newsletter, we'll examine some of the potential problems that may  arise from the consumption of supplemental doses of omega–3 fatty acids.&lt;/p&gt;
&lt;p class="style20"&gt;&lt;strong&gt;Articles In This Series:&lt;/strong&gt;&lt;/p&gt;
&lt;p class="style20"&gt;&lt;strong&gt;&lt;span style="color: #005d86;"&gt;A Diet For Long-Term Weight Control and Optimal Health:&lt;/span&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p class="style20"&gt;&lt;a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2010/12/a-diet-for-long-term-weight-control-and-optimal-health-part-1.html" target="_self"&gt;Part 1- Sugars And Carbohydrates From An Addiction Perspective&lt;/a&gt;&lt;/p&gt;
&lt;p class="style20"&gt;&lt;a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2010/12/the-integrated-supplements-newsletter-a-diet-for-long-term-weight-control-and-optimal-health-part-2-.html" target="_self"&gt;Part 2 - The True Role of Sugar in Weight Gain, Diabetes, and Metabolic Syndrome&lt;/a&gt;&lt;/p&gt;
&lt;p class="style20"&gt;&lt;a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2010/12/integrated-supplements-newsletter-a-diet-for-long-term-weight-control-and-optimal-health-part-3-in-d.html" target="_self"&gt;Part 3 - In Defense of Fruit&lt;/a&gt;&lt;/p&gt;
&lt;p class="style20"&gt;&lt;a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/03/a-diet-for-long-term-weight-control-and-optimal-health-part-4-fatty-acid-intake-in-industrial-versus.html" target="_self"&gt;Part 4 - Fatty Acid Intake In Industrial Versus Traditional Diets&lt;/a&gt;&lt;/p&gt;
&lt;p class="style20"&gt;&lt;a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/05/a-diet-for-long-term-weight-control-and-optimal-health-part-5-the-role-of-modern-fats-in-heart-disea.html" target="_self"&gt;Part 5 - The Role of Modern Fats in Heart Disease, Cancer, and Obesity&lt;/a&gt;&lt;/p&gt;
&lt;p class="style20"&gt;&lt;a href="http://integratedsupplements.typepad.com/integrated_supplements_bl/2011/06/a-diet-for-long-term-weight-control-and-optimal-health-part-6-essential-fatty-acids-and-metabolic-di.html" target="_self"&gt;Part 6 - Essential Fatty Acids and Metabolic Disruption&lt;/a&gt;&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p class="style20"&gt;&lt;em&gt;&lt;strong&gt;About Us:&lt;/strong&gt; At Integrated Supplements, our goal is to bring you the wellness information and products you need to live your life to the fullest. We are dedicated to producing the highest–quality, all–natural nutritional supplements; and to educating the world on the health promoting power of proper nutrition. You can find out more by visiting: &lt;a href="http://www.integratedsupplements.com/intsup/intsup0001.homepage"&gt;www.IntegratedSupplements.com&lt;/a&gt;&lt;/em&gt;&lt;/p&gt;
&lt;p class="style20"&gt;&amp;nbsp;&lt;/p&gt;
&lt;p class="style20"&gt;These statements have not been evaluated by the FDA.  No Integrated Supplements product is intended to diagnose, treat, cure or prevent any disease.&lt;/p&gt;&lt;/div&gt;
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