https://jurnal.fk.unand.ac.id/index.php/jka Jurnal Kesehatan Andalas Faculty of Medicine, Universitas Andalas en-US Jurnal Kesehatan Andalas 2301-7406 <p>Authors retain copyright and grant the Jurnal Kesehatan Andalas right of first publication with the work simultaneously licensed under a <strong><a href="https://creativecommons.org/licenses/by-sa/4.0/" target="_blank" rel="noopener">Creative Commons Attribution-ShareAlike (CC BY-SA 4.0) license</a></strong> that allows others to <strong>share</strong> (copy and redistribute the material in any medium or format) and <strong>adapt </strong>(remix, transform, and build upon the material) the work for any purpose, even commercially with an acknowledgement of the work's authorship and initial publication in Jurnal Kesehatan Andalas.<br /><br />Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in Jurnal Kesehatan Andalas.<br /><br />Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).</p> https://jurnal.fk.unand.ac.id/index.php/jka/article/view/2653 <p><strong>Analysis of physical activity, online gaming addiction, and nutritional status of students at Sekolah Menengah Pertama Negeri 4 and 18 in Pontianak City</strong></p> <p>Adolescent obesity is increasing in line with low physical activity levels and the high prevalence of online gaming. A sedentary lifestyle, such as excessive gaming, may reduce physical activity and negatively affect nutritional status. <strong>Objective</strong>: To determine the correlation between physical activity and online gaming with nutritional status among students at the junior high schools Sekolah Menengah Pertama Negeri 4 and 18 in Pontianak city<strong>. Methods</strong>: This research was an observational analytic study with a cross-sectional design. The sample consisted of 190 students selected using purposive sampling. Physical activity was assessed using the PAQ-A questionnaire, online gaming with the GASA questionnaire, and nutritional status by measuring height and weight. Data were analyzed using Spearman’s correlation test. <strong>Results</strong>: Most students had a moderate level of physical activity (98 students; 51.6%), a moderate frequency of online gaming (125 students; 65.8%), and normal nutritional status (150 students; 78.9%). The analysis showed no significant correlation between physical activity (p = 0.499) or online gaming (p = 0.073) and nutritional status among students at SMPN 4 and 18 Pontianak. <strong>Conclusion</strong>: Levels of physical activity and online gaming addiction did not significantly affect the nutritional status of early adolescents at Sekolah Menengah Pertama Negeri 4 dan 18 Pontianak.</p> <p><strong>Keywords</strong>: physical activity, online games, nutritional status, adolescents, junior high schools</p> <p> </p> Fikri Akifa Permana Agustina Arundina Triharja Tejoyuwono Ita Armyanti Copyright (c) 2026 Fikri Akifa Permana, Agustina Arundina Triharja Tejoyuwono, Ita Armyanti https://creativecommons.org/licenses/by-sa/4.0 2026-03-29 2026-03-29 15 1 1 6 10.25077/jka.v15i1.2653 https://jurnal.fk.unand.ac.id/index.php/jka/article/view/2672 <p><strong>Comparison of SOFA scores in septic patients with and without type 2 diabetes mellitus</strong></p> <p>Sepsis is a life-threatening organ dysfunction. A dysregulated host response to infection causes it. Organ dysfunction can be represented by an increase in the SOFA score of &gt; 2 points. Every increase in the score reflects worsening of organ dysfunction. Type-2 Diabetes Mellitus (T2DM) is one of the most common comorbidities in sepsis patients. T2DM patients have chronic hyperglycemia. This condition can impair immune function and damage the endothelium. <strong>Objective</strong>: To find out the comparison of SOFA scores in sepsis patients with and without T2DM. <strong>Methods</strong>: This research was an analytical, cross-sectional study using medical record data from RSUP Dr. M. Djamil Padang. The 132 samples comprised 66 sepsis patients with T2DM and 66 without T2DM. Sampling was carried out by using a stratified random sampling technique. Bivariate data analysis used an independent-samples t-tes. The mean of SOFA scores in sepsis patients with T2DM was 8.05 +_ 2.36 and the mean of SOFA scores in sepsis patients 6.38 +_ 2.96. The p-value (&lt;0,05) in both groups was 0.001. <strong>Conclusion</strong>: There is a significant difference in SOFA scores between sepsis patients with and without T2DM.</p> <p><strong>Keywords</strong>: sepsis, SOFA score, T2DM</p> Munsyi Nares Wari Fadrian Eti Yerizel Mohamad Reza Dinda Aprilia Eka Nofita Copyright (c) 2026 Munsyi Nares Wari, Fadrian, Eti Yerizel , Mohamad Reza , Dinda Aprilia , Eka Nofita https://creativecommons.org/licenses/by-sa/4.0 2026-03-29 2026-03-29 15 1 7 13 10.25077/jka.v15i1.2672 https://jurnal.fk.unand.ac.id/index.php/jka/article/view/2720 <p><strong>Relationship between education level, employment status, and differences in average food intake among pregnant women: A cross-sectional study on pregnant women in West Sumatra Province</strong></p> <p>A pregnant woman will experience weight gain. Many factors influence weight gain in pregnant women, such as level of education, employment status, and food intake. <strong>Objective: </strong>To determine the relationship between education level, employment status, and variations in average dietary intake on weight gain among pregnant women. <strong>Methods</strong>: A cross-sectional study was conducted in West Sumatra Province with 183 respondents. Data on pregnant women's weight, employment status, education level, and food intake were obtained from secondary data sources, including maternal weight measurements, sociodemographic data, and the SQ-FFQ. The analysis uses the Chi-square test and one-way ANOVA. <strong>Results:</strong> The relationship between education level and employment status with weight gain of pregnant women were obtained with values of p=0.661 and p=0.977, and the difference between the average food intake (energy, carbohydrates, protein, and fat) with the weight gain of pregnant women was obtained sequentially, with values of p=0.179, 0.568, 0.143, and 0.104. <strong>Conclusion</strong>: There was no significant relationship between job status and education level and weight gain of pregnant women, and there was no significant average difference between food intake and weight gain of pregnant women.</p> <p><strong>Keywords</strong>: education level, employment status, food intake, pregnancy weight gain</p> Fristy Dwinanda Ralni Nur Indrawati Lipoeto Zurayya Fadila Copyright (c) 2026 Fristy Dwinanda Ralni, Nur Indrawati Lipoeto, Zurayya Fadila https://creativecommons.org/licenses/by-sa/4.0 2026-03-29 2026-03-29 15 1 14 25 10.25077/jka.v15i1.2720 https://jurnal.fk.unand.ac.id/index.php/jka/article/view/2668 <p><strong>Administration of snakehead fish (Channa striata) extract in chronic kidney disease with anasarca edema, diabetes mellitus, and hypertension: A case report</strong></p> <p>Chronic kidney disease (CKD) is a global health problem often accompanied by complications such as anasarca edema, anemia, and protein-energy malnutrition, particularly in patients with diabetes mellitus and hypertension. This condition requires innovative nutritional strategies to support clinical recovery. Snakehead fish (Channa striata), which is rich in protein, essential amino acids, and micronutrients, has been suggested as a potential supportive therapy. Scientific evidence regarding its benefits in CKD management remains limited. This case report presents nutritional care for a male patient with stage V CKD, anasarca edema, diabetes mellitus, and hypertension. The identified nutritional problems included decreased renal function requiring hemodialysis and endocrine metabolic disturbances; therefore, the nutritional intervention focused on a high-protein, low-simple-carbohydrate diet, Oral Nutrition Support (ONS), and snakehead extract supplementation (50 mL/day for six days). Monitoring outcomes showed an increase in dietary intake up to 75% of requirements, improvement in hemoglobin levels from 8.2 g/dL to 8.5 g/dL, and clinical improvements, including reduced nausea, decreased edema, and lowered blood pressure from 203/106 mmHg to 146/72 mmHg. Snakehead extract supplementation has the potential to serve as an effective supportive intervention to improve hemoglobin levels, clinical status, and nutritional outcomes in CKD patients with complications.</p> <p><strong>Keywords</strong>: anasarca edema, chronic kidney disease, diabetes mellitus, nutritional intervention, snakehead fish</p> <p> </p> Khoirunisa Khanifa Meirina Dwi Larasati Yuniarti Luhur Ngudi Setyaningrum Copyright (c) 2026 Khoirunisa Khanifa, Meirina Dwi Larasati, Yuniarti, Luhur Ngudi Setyaningrum https://creativecommons.org/licenses/by-sa/4.0 2026-03-29 2026-03-29 15 1 45 51 10.25077/jka.v15i1.2668 https://jurnal.fk.unand.ac.id/index.php/jka/article/view/2685 <p><strong>Non-pharmacological prevention strategies for allergic rhinitis in addressing the limitations of long-term antihistamine therapy: A systematic review</strong></p> <p>Antihistamine therapy in Allergic rhinitis is generally the primary choice for symptom management. However, long-term use often presents side effects such as sedation, tolerance, and lack of control over allergen exposure. Non-pharmacological preventive strategies are important to explore as complementary and alternative approaches. <strong>Objective</strong>: To analyze effective non-pharmacological strategies for the prevention of allergic rhinitis. <strong>Methods</strong>: A literature search was conducted across electronic databases such as PubMed, Scopus, and Google Scholar, focusing on publications published between 2015 and 2024. The selected studies included experimental studies, systematic reviews, and clinical guidelines addressing non-pharmacological interventions for allergic rhinitis. The most frequently discussed non-pharmacological strategies included environmental controls (e.g., reducing exposure to dust, mites, and air pollution), nasal saline irrigation, mask use, lifestyle modifications, and patient education. <strong>Results</strong>: Several interventions have shown significant reductions in symptom scores and improvements in patients' quality of life, especially when combined with pharmacological therapy. Non-pharmacological approaches have significant potential as long-term management strategies for allergic rhinitis. <strong>Conclusion</strong>: The combination of education, environmental modifications, and physical interventions can reduce symptom frequency and the need for antihistamines.</p> <p><strong>Keywords</strong>: allergic rhinitis, antihistamines, environmental modifications, non-pharmacological, prevention</p> Iwan Setiawan Adji Sabira Husna Ristyana Noval Gentha Mahensa Witrishya Anggrahini Aisyah Nabilah Marshanda Ariella Nadhifa Lina Nur Fatimah Dhia Laila Nadzifa Copyright (c) 2026 Iwan Setiawan Adji, Sabira Husna Ristyana, Noval Gentha Mahensa, Witrishya Anggrahini, Aisyah Nabilah, Marshanda Ariella Nadhifa, Lina Nur Fatimah, Dhia Laila Nadzifa https://creativecommons.org/licenses/by-sa/4.0 2026-03-29 2026-03-29 15 1 26 34 10.25077/jka.v15i1.2685 https://jurnal.fk.unand.ac.id/index.php/jka/article/view/2706 <p><strong>The role of oxidative stress in essential hypertension: A systematic review</strong></p> <p>Oxidative stress plays a crucial role in the pathogenesis of essential hypertension. It leads to endothelial dysfunction, reduced nitric oxide (NO) bioavailability, and increased arterial stiffness, all of which contribute to elevated blood pressure. <strong>Objective</strong>: To analyze the role of oxidative stress in the pathogenesis of essential hypertension. <strong>Methods</strong>: This study was a literature review conducted by searching PubMed, ScienceDirect, and Cochrane databases from 2021 to 2025 using the keywords “Hypertension AND Oxidative Stress AND Correlation.” Of the 2700 identified articles, six studies met the inclusion and exclusion criteria and were analyzed further. <strong>Results</strong>: All selected studies demonstrated a strong relationship between oxidative stress and hypertension. Increased production of Reactive Oxygen Species (ROS) impairs endothelial function, reduces NO levels, and increases arterial stiffness. Interventions using antioxidants, such as melatonin, and dietary nitrates improved vascular function and oxidative balance. However, the outcomes varied depending on the type and dosage of antioxidants used. <strong>Conclusion</strong>: Oxidative stress plays a key role in the development of essential hypertension through endothelial damage, vascular dysfunction, and activation of the renin-angiotensin system. Antioxidant-based interventions, particularly melatonin, show promising potential to improve redox balance and reduce blood pressure. Further studies are needed to establish their long-term efficacy and safety.</p> <p><strong>Keywords</strong>: antioxidants, essential hypertension, oxidative stress, melatonin, nitric oxide</p> <p> </p> Nur Ramadani Arban Mohammad Zulkarnain Emma Novita Copyright (c) 2026 Nur Ramadani Arban, Mohammad Zulkarnain, Emma Novita https://creativecommons.org/licenses/by-sa/4.0 2026-03-29 2026-03-29 15 1 35 44 10.25077/jka.v15i1.2706