LabOnline RSS Feed

MBF Bioscience SLICE high-performance light sheet microscope

Mon, 01 Jun 2026 00:00:00 +1000

MBF Bioscience’s SLICE Light-Sheet Microscope is engineered to expand access to high-performance 3D imaging by combining research-grade capability with a compact, cost-effective benchtop format. SLICE is designed to support a broad range of applications across neuroscience, cancer research, developmental biology, tissue engineering, core imaging facilities, and translational research in biotechnology and pharmaceutical environments.

SLICE is designed to deliver performance comparable to substantially more expensive systems, with approximately 1 µm lateral resolution and 5 µm axial resolution for imaging cells and fine neuronal processes throughout cleared tissue. The platform also offers three-wavelength imaging capability for flexible multi-channel imaging applications.

Designed to meet the practical needs of modern neuroscience and biology laboratories, SLICE is engineered to reduce the infrastructure demands often associated with advanced light-sheet imaging. Originating from the Tomer Lab at Columbia University and based on Projected Light Sheet Microscopy (Chen et al., 2024), the system received the 2025 Microscopy Today Innovation Award and is now installed at more than 30 leading research institutions across three continents.

The system is designed to support imaging of whole mouse brains, cleared organs and organoids at sub-micron resolution, while accommodating major clearing workflows, including iDISCO, CLARITY, CUBIC and BINAREE, without requiring hardware changes. Its benchtop footprint eliminates the need for a vibration isolation table, while BrightSLICE software is designed to provide an integrated environment for image acquisition, processing and visualisation without requiring separate licensing or third-party software assembly.

SLICE is engineered to be a practical, research-ready platform for laboratories seeking high-quality 3D imaging in a compact and accessible format.

Malvern Panalytical MicroCal PEAQ-ITC isothermal titration calorimeter for measuring binding affinity and stoichiometry

Mon, 01 Jun 2026 00:00:00 +1000

Understanding binding affinity is central to interpreting the intermolecular interactions that drive biological processes, structural biology and structure–function relationships. It is also central to drug discovery, where accurate measurement of binding strength and specificity underpins the design of effective, targeted therapeutics.

The MicroCal PEAQ-ITC from Malvern Panalytical is engineered to be an essential tool for biological interaction analysis, delivering precise measurements of affinity and stoichiometry in a single, label-free experiment.

While many isothermal titration calorimetry (ITC) systems provide basic thermodynamic data, they often are limited by sensitivity, complex workflows and data uncertainty. The PEAQ-ITC is designed to overcome these limitations through a combination of advanced hardware and intelligent software. Unmatched signal stability and lower noise compared to other systems are designed to enable accurate analysis of weak or complex interactions, even at low concentrations. Its enhanced sensitivity is designed to enable detection of interactions (eg, protein–protein, protein–small molecule and protein–nucleic acid) that many other systems simply cannot resolve.

Critically, common sources of error — such as inactive protein fractions or inaccurate ligand concentrations — can significantly distort binding data. PEAQ-ITC’s advanced analysis software is engineered to identify and correct these issues, allowing researchers to recover reliable thermodynamic parameters and improve confidence in structure–activity relationship (SAR) studies.

Ease of use is another defining feature. With PEAQ-Expert guidance tools, automated data quality assessment and rapid experiment-to-result workflows, users can generate high-quality data in under 30 minutes with low sample consumption and fully automated operation. By combining superior sensitivity and streamlined workflows, the MicroCal PEAQ-ITC is designed to deliver more accurate, reproducible data.

For more information: https://www.atascientific.com.au/products/malvern-microcal-peaq-itc/.

GeneFrontier PUREfrex cell-free protein synthesis system

Mon, 01 Jun 2026 00:00:00 +1000

PUREfrex from GeneFrontier is designed to be a breakthrough in cell-free protein synthesis technology, offering a precisely engineered in vitro coupled transcription/translation system. Unlike traditional S30 translation extracts, PUREfrex utilises a completely reconstituted system derived from E. coli translation machinery. By adding DNA or mRNA that encodes the target protein to the reaction solution, proteins can be synthesised easily and quickly without using living cells.

Features of the PUREfrex protein synthesis system include: protein expression in hours instead of days; highly purified components that eliminate contaminating nucleases and proteases; DNA and RNA template for integrity preservation; and maintaining optimal protein functionality.

Other features include: maximum yield of full-length target proteins; to express proteins with any tag, including polyhistadine (HIS); that PUREfrex components can be customised to meet the expression demands of a unique protein; and that PUREfrex volumes are easily scalable for protein production from µL to L quantities.

United Bioresearch Products distributes the full range of PUREfrex products in Australia.

For more information, click here.

Camfil CamSafe 3 safety housing

Mon, 01 Jun 2026 00:00:00 +1000

Camfil CamSafe 3 Housing is a modular, high integrity safe change housing system designed to ensure maximum containment and operator safety when handling contaminated air. It is engineered for exhaust air applications in critical environments including biosafety levels L1 to L3+, pharmaceutical and chemical processing, hospitals, laboratories, and animal research facilities.

The system is highly configurable, available in single or multi module designs to suit a wide range of airflow requirements and filtration stages. It supports both particulate and molecular filtration, offering flexibility for diverse contamination control needs.

CamSafe 3 incorporates a patented clamping mechanism with a single action lever and dual safety interlock, designed to ensure correct filter positioning and consistent gasket compression. Its integrated service bag collar is engineered to enable fully contained Bag In Bag Out (BIBO) filter changes, allowing safe removal and replacement of filters without exposure to hazardous contaminants.

The housing is designed for high pressure integrity and has been rigorously tested at ±6000 Pa, meeting stringent international standards including EUROVENT 2/2 Class C, EN 1886 Class L1, ISO 10648-2 Class 3, and EN 12237 Class D.

For performance verification, CamSafe 3 supports Manual Integrity Probe scanning within the housing and optional ducted injection modules for efficient leak testing using reduced aerosol volumes. A wide range of accessories, including dampers, supports, collectors, and decontamination options, further enhances system adaptability.

CamSafe 3 is designed to deliver a robust, flexible and highly secure containment solution tailored to critical air filtration environments where safety and reliability are essential.

For more information, click here.

Malvern Panalytical NanoSight Pro for precision in drug delivery nanoparticle analysis

Fri, 01 May 2026 00:00:00 +1000

As nanoparticle-based drug delivery advances modern therapeutics, accurate characterisation has never been more critical. From liposomes to polymer nanoparticles, size and concentration directly influence targeting efficiency, circulation time and therapeutic performance. The Malvern Panalytical NanoSight Pro is engineered to address this challenge with an advanced nanoparticle tracking analysis (NTA) platform. NanoSight Pro is a widely adopted NTA solution in biomaterials research designed to deliver rapid and robust, highly repeatable results.

The NanoSight Pro visualises and tracks individual particles in real time, measuring size distribution — typically ranging from 10 to 1000 nm — and concentration simultaneously. This particle-by-particle approach is designed to enable users to quickly assess critical quality attributes with minimal sample preparation, making it suitable for complex drug delivery systems.

A key advantage is its ability to combine light scatter and fluorescence detection. This allows users to distinguish between nanoparticle populations — such as empty versus cargo-loaded liposomes — even when sizes are similar. This capability is vital for formulation optimisation and controlled delivery.

NanoSight Pro is designed to overcome common limitations of traditional NTA systems. Automated workflows are designed to reduce user bias and improve reproducibility, while intelligent analysis algorithms are designed to reduce variability and ensure consistent results. In addition, flow-based measurements are designed to overcome issues of low particle statistics and sampling bias seen in static systems, improving data robustness. Enhanced optics and detection sensitivity are designed to also minimise background noise and improve accuracy when analysing polydisperse or low-concentration samples.

With intuitive NS Xplorer software and real-time visualisation, the platform aims to ensure researchers can confidently analyse each particle as it is measured.

To learn more, or book a personal NanoSight Pro demo, visit https://www.atascientific.com.au/products/malvern-nanosight-pro/.

Azure Biosystems Western Blot Imaging Systems

Fri, 01 May 2026 00:00:00 +1000

Azure Biosystems offers a range of high-performance Western blot imaging systems designed for versatility and precision. Azure Biomolecular Imagers support near-infrared (NIR) fluorescence, visible fluorescence and chemiluminescence, enabling comprehensive documentation and quantitative analysis across a wide range of applications. These include gels, Western blots, slides, tissue samples, small animal models, plants and media plates.

The Azure imaging family is engineered to deliver fast, sensitive, high-resolution detection using 9MP CCD technology, all within a compact, benchtop-friendly design. Models are available across the 200, 280, 300, 400, 500 and 600 series, offering flexible solutions to meet diverse research needs. These multimodal, multichannel systems feature NIR, visible light and UV excitation, allowing detection of a broad range of dyes, including Cy dyes, Alexa dyes, Safe dyes and trihalo compound-based gels.

The Azure Cielo Real-Time PCR System is engineered to generate high-quality qPCR data through advanced optical performance and broad-spectrum detection. It is designed to offer excellent specificity, precision, fast run times and reproducibility. Key applications include gene expression analysis (quantitative and qualitative), miRNA analysis, genetic mapping and fingerprinting, NGS library quantification, pathogen detection and six-channel multiplexing.

The chemiSOLO is a compact, personal chemiluminescent imager designed for high-quality quantitative imaging. It is suitable for applications such as chemiluminescent Western blotting, densitometry and visible gel imaging.

The Sapphire Biomolecular Imager features a unique, patent-pending three-detector system combined with laser-based excitation that minimises background noise. This hybrid laser scanner-CCD platform is designed to deliver best-in-class performance across chemiluminescence, visible and NIR fluorescence, and phosphor imaging.

Proteintech FlexAble Oligo-Ready Labeling Kits

Thu, 09 Apr 2026 00:00:00 +1000

Proteintech’s FlexAble Oligo-Ready Labeling Kits are used for generating Oligo-FlexLinker conjugates, which enable species-specific and high-affinity labelling of antibodies, providing a fast, easy way to label primary antibodies with Oligos.

The kits are designed to offer maximum flexibility, allowing users to label only what they really need. There is no need to label 100 µg of antibody even though atypical immunofluorescence (or other) workflow may only use a few micrograms. With the FlexAble Oligo-Ready kit, users gain full flexibility: prepare FlexLinkers, select the antibodies the user wants to modify, and label as little as 0.5 µg of antibody.

The innovative FlexAble technology allows for easy multiplexing, even with same species antibodies.

It’s also designed to make it simple for the user to build their own barcode library. A single FlexAble Oligo-Ready Antibody Labeling Kit allows the user to prepare up to three Oligo-FlexLinkers with three different oligos, enabling the user to create their own custom barcode library. The resulting Oligo-FlexLinkers are stable and can be stored long-term at −20°C. From there, labelling antibodies with the user’s barcode takes only 15 minutes.

For further information, contact United Bioresearch Products, which distributes the full range of Proteintech products in Australia.

Camfil Absolute V HEPA Filter

Thu, 02 Apr 2026 00:00:00 +1100

The Absolute V, VEXL and VEXXL HEPA filters are designed to be robust, lightweight solutions engineered for both supply and exhaust air systems where very high airflow and minimal pressure drop are essential. The Absolute VEXL and VEXXL stand out with a modern steel frame and V-shaped pleat pack, designed to offer the industry’s highest capacity and stability while achieving the lowest pressure drop and weight.

Capable of handling airflows up to 3.7 m/s, they deliver 23% energy savings over the market average and are claimed to be the lightest V-bank steel HEPA filters available. Each filter is individually scan-tested to guarantee 100% leak-free performance, and a strong, airtight frame is intended to ensure secure and reliable installation. Designed for Bag-in Bag-out safe change, they aim to provide the most convenient handling and maintenance.

Suitable for demanding pharmaceutical, healthcare, and food and beverage environments, these filters integrate seamlessly with air-handling units, HEPA housings and isolators. Their advanced design is engineered to protect against a broad spectrum of airborne contaminants while maintaining excellent indoor air quality. With a construction 41% lighter than the previous range and a 21% longer filter life, the Absolute V family is designed to simplify operations and reduce facility downtime. Absolute V is ProSafe certified and fully compliant with EC1935:2004, VDI6022 and ISO 846 standards.

For more information: www.camfil.com.

Micropore Technologies Advanced Crossflow (AXF) platform

Wed, 01 Apr 2026 00:00:00 +1100

Crystallisation is a critical step in the manufacture of active pharmaceutical ingredients (APIs). The size, shape and polymorphic form of API crystals directly influence drug properties such as solubility, bioavailability and stability. However, achieving consistent crystallisation can be challenging. Traditional methods like batch cooling or anti‑solvent addition often struggle to deliver tight control over nucleation, particle size distribution, morphology and polymorphism — leading to inconsistent material, broad size distributions and significant post‑processing requirements such as milling or additional purification steps. While these approaches remain widely used, they are often difficult to reproduce and scale reliably, creating bottlenecks in development and manufacture.

Micropore Technologies aims to address these challenges through its patented Advanced Crossflow (AXF) platform, which uses precision-engineered membranes to control mixing conditions during particle formation. This membrane‑based approach has been widely explored for API crystallisation through both reactive and antisolvent crystallisation methods. The platform is designed to enable control over crystal size, morphology and polymorphic form, helping researchers tailor APIs for improved processability and bioavailability. Low shear conditions also protect sensitive materials during processing.

Key benefits include repeatable and reproducible control of crystal size and morphology, the ability to selectively produce desirable API forms or amorphous material and the capability to generate API nanocrystals to enhance dissolution and bioavailability. The continuous system is engineered to be scalable from early research and development through pilot and industrial production, support aseptic processing with in-line process analytical technology and reduce downstream processing of API crystals by delivering precise control over crystal size distribution.

Book a Micropore AXF series demo or request a trial at https://www.atascientific.com.au/products/micropore-axfseries.

Tomocube HT-X1 mini 3D holotomography system

Sun, 01 Mar 2026 00:00:00 +1100

Scitech, in partnership with Tomocube, is proud to announce the launch of the HT-X1 mini, a compact and flexible holotomography platform designed to bring high-resolution, label-free 3D imaging to a wider range of laboratories. Combining cutting-edge imaging technology with a user-friendly design, the HT-X1 mini is engineered to enable researchers in cell biology, immunology, regenerative medicine and high-content 3D imaging to capture live cells in their natural state without perturbation.

Weighing just 30 kg, the HT-X1 mini is engineered to fit seamlessly into even the most space-constrained environments, from cell culture rooms to clinical and field laboratories. Its plug-and-play usability ensures research teams can rapidly integrate advanced 3D imaging into their workflows, transforming routine experiments into high-impact discoveries.

At the heart of the HT-X1 mini is Tomocube’s second-generation holotomography technology, which delivers high-resolution 3D refractive index maps of live cells. The system is fully compatible with TomoAnalysis, Tomocube’s image analysis suite, providing researchers with seamless continuity from data acquisition to quantitative analysis.

Understanding that research needs evolve, the HT-X1 mini is built with modular flexibility. Laboratories can begin with essential imaging capabilities and later expand to include fluorescence imaging, environmental incubation, laser-based autofocus and multi-wavelength illumination, ensuring the platform can grow alongside their research. This versatility supports everything from routine cell monitoring to complex, high-content 3D studies.

The HT-X1 mini combines a 40× NA 0.75 air objective lens, a 2.8 MP CMOS image sensor, LED illumination at 444 nm (with optional 520 and 660 nm wavelengths), and a motorised stage for precise sample positioning. Optional modules for multi-channel fluorescence, laser-based autofocus and environmental control further enhance its capabilities, making advanced live-cell 3D imaging more accessible.

The HT-X1 mini is designed to democratise high-resolution, label-free 3D imaging, giving researchers the tools to observe cellular processes in unprecedented detail while maintaining flexibility, ease of use, and adaptability for future research demands.

Malvern Panalytical Mastersizer 3000+ particle size analysis with automated guidance

Sun, 01 Mar 2026 00:00:00 +1100

Launched in 2012, the Mastersizer 3000 particle size analyser is designed to be the instrument of choice for high performance, reliability and compact design. The Mastersizer 3000+ from Malvern Panalytical builds on this legacy by placing practical guidance and automation at the centre of the user experience.

At its core, the Mastersizer 3000+ uses laser diffraction to measure particle size distributions across a broad range — from the nanoscale into the millimetre range — in both wet and dry dispersions. Its intuitive Mastersizer Xplorer software is engineered to provide built-in expert guidance that supports users of all experience levels through every stage of the measurement process, from initial sample set-up to final reporting, reducing training time and helping ensure consistent results across operators.

Over time, features and accessories have expanded alongside software modules such as Smart Manager, which helps optimise instrument uptime and usage, and OmniTrust, which supports regulatory compliance and data integrity.

A stand-out feature for practical laboratory use is SOP Architect, an intelligent method development assistant embedded in the software. SOP Architect leads users step-by-step through standardised workflows, embedding best-practice guidance and automating key tasks such as stirrer speed optimisation, obscuration titrations and ultrasound dispersion decisions. This simplifies method development and supports robust, reproducible procedures.

For routine analysis, Size Sure is designed to improve confidence in results by helping users mitigate environmental influences such as contamination and the effects of unstable conditions. Data Quality Guidance offers real-time feedback to help users assess data quality. Together, these tools are designed to help generate reliable data to speed up analysis and support informed decision-making.

The Mastersizer Auto-Lab is the Autosampler option which can measure up to 42 samples while maintaining the same analytical flexibility as manual operation.

Book a Mastersizer 3000+ demo or request a trial at www.atascientific.com.au/products/malvern-mastersizer-3000-ultra.

Camfil CleanSeal AU terminal HEPA housing

Sun, 01 Feb 2026 00:00:00 +1100

Camfil’s CleanSeal AU is a robust, fully welded ceiling housing, specifically engineered for the Australian market. Designed to deliver reliable performance and ease of use, it is suited to cleanrooms, laboratories and life science facilities where precision airflow and contaminant control are critical. The housing can be customised to suit specific finishes, formats or fully bespoke ceiling integrations, providing flexibility to meet the unique requirements of any facility.

Equipped with a full suite of measurement ports, CleanSeal AU enables accurate filter validation and monitoring, making it suitable for both supply and exhaust air applications. The premium integrity variant supports ISO 14644-3 in-situ testing, offering a complete installation kit for high-performance cleanroom environments.

CleanSeal AU is compatible with both PU and GEL gaskets and features a universal mounting system, allowing for suspended or compression installations. Its pre-positioned filter retainers and patented adjustable clamping system accommodate all Camfil Megalam HEPA filter sizes (MG/MD/MX), facilitating quick upgrades to maintain pressure cascades and enhance energy efficiency.

Key advantages include: stainless steel filter retaining section for gasket or gel seal HEPA filters and diffusers; quick front plate locking for immediate filter access; perforated diffuser standard, with alternative options available; powder-coated plenum standard, optional stainless-steel finish; and optional adjustable damper for precise room airflow control.

CleanSeal AU is engineered to combine durability, flexibility and compliance with stringent cleanroom standards, making it a reliable solution for maintaining optimal airflow, pressure control and energy-efficient operation in demanding life science and pharmaceutical environments.

For more information, contact the company or submit your enquiry at www.camfil.com.

Cellbox Go portable, lightweight CO2 incubator

Sun, 01 Feb 2026 00:00:00 +1100

For decades, cell transport has relied on freezing, despite costly trial-and-error and frequent cell loss. Shipping frozen cells is risky and inefficient.

Enabled by the Cellbox from Cellbox Solutions (Germany), warm chain logistics offers an alternative approach that keeps cells alive and thriving during transport. Cellbox is a portable CO₂ incubator designed for ground or air transport, maintaining 37°C and 5% CO₂ throughout the journey. The solution is designed to ensure cells arrive healthy, metabolically active and ready to use — and often in better condition than if they had remained static in a lab incubator.

Two models are available: Cellbox Shipper, ideal for long-distance transport, and Cellbox Go, a lightweight, backpack-ready system designed for flexibility. Both are available in ground and flight-approved configurations.

In Australia, where distances are vast and research happens everywhere — from city labs to remote field sites — Cellbox is engineered to be more than a shipper. Intended to be a mobile incubator for microscopy sessions, field research, clinical trials and beyond. It’s shipped neuronal cells across Sydney, run patient-derived cells in Qld for clinical trials and even helped research in Ningaloo.

To book a Cellbox Go or request a trial, contact the company or visit https://www.atascientific.com.au/products/cellbox-go-ground-or-flight/.

Azure Biosystems Sapphire FL+ large-format biomolecular imager

Tue, 13 Jan 2026 00:00:00 +1100

From large-format phosphor screens to high-throughput imaging workflows, the Sapphire FL+ by Azure Biosystems offers a 46 x 25 cm scanning bed — a scan area spacious enough to accommodate even oversized samples. From western blots to 2D gels, microscope slides, model organism imaging, multi-well plates, tissue arrays and protein arrays, the product is designed to provide high flexibility and precise quantitation of molecular assays.

The Sapphire FL+ has been billed as one of only two scanners in its class that supports phosphor imaging — a highly sensitive assay that utilises radioactivity. It can scan storage phosphor screens up to 20 x 40 cm, delivering 24-bit dynamic range and high image quality through its use of laser excitation and photon multiplier tube (PMT) detection.

The Sapphire FL+ features a novel, patent-pending design of interchangeable and customisable laser and filter modules, enabling a virtually infinite number of spectral combinations. A broad range of excitation and emission wavelengths, as well as phosphor imaging, are supported.

The instrument offers laser options from UV to NIR wavelengths (375–900 nm), 5–1000 μm resolution scans and a Z-plane range from -1 to +6 mm. Whether imaging western blots, gels, 96-well plates or tissue slides, the adjustable Z-plane provides optimal focus for every sample.

An optional Chemiluminescence Module adds high-resolution, quantitative chemiluminescence and visible imaging. It allows users to capture proteins with femtogram sensitivity and provides the ability to capture colour marker images.

Logos Biosystems X-CLARITY system for streamlined tissue clearing

Thu, 01 Jan 2026 00:00:00 +1100

Visualising intact biological structures in three dimensions remains a major challenge for researchers. Conventional histology techniques require thin tissue slicing, which can distort spatial relationships and make it difficult to interpret complex cellular networks. Thick or whole-tissue imaging, on the other hand, is hindered by light scattering caused by lipids, leading to opaque samples and poor imaging depth. There is a growing need for standardised clearing methods to clear tissues efficiently without damaging structure or losing fluorescent signals.

The X-CLARITY system from Logos Biosystems addresses these challenges by automating and standardising the tissue clearing process. Using proprietary electrophoretic tissue clearing (ETC) technology, the system rapidly and uniformly removes lipids from fixed tissues, rendering them optically transparent while maintaining molecular and structural integrity.

The X-CLARITY tissue clearing system, together with dedicated hydrogel and mounting solutions, provides an all-in-one, easy-to-use workflow from start to finish. The process can clear a mouse brain in just a few hours, eliminating manual variability and improving consistency across samples.

Once cleared, tissues can be imaged using confocal, two-photon or light sheet microscopy to reveal intricate 3D architecture — from neuronal pathways and vascular networks to tumour microenvironments. By simplifying and accelerating tissue clearing, the system empowers researchers in neuroscience, developmental biology and pathology to gain deeper insight into biological systems.

ATA Scientific provides demonstrations and expert support to help laboratories adopt this transformative workflow. To see the benefits for yourself, contact the company or visit https://www.atascientific.com.au/products/logos-biosystems-x-clarity/.

Meling -86°C TwinDrive Ultra Low Temperature Freezer

Thu, 01 Jan 2026 00:00:00 +1100

The Meling -86°C TwinDrive Ultra Low Temperature Freezer is designed with dual independent refrigeration systems, ensuring that if one system fails, the other maintains temperatures around -75 to -80°C, protecting samples. This redundancy makes it far safer than traditional single-compressor freezers, which risk sample loss in the event of failure.

Meling’s TwinDrive technology also delivers uniform cooling with minimal fluctuation, guaranteeing consistent -86°C storage conditions. The system achieves rapid temperature recovery after door openings, reducing risk during routine access. Each compressor operates under reduced load, extending service life and lowering maintenance costs.

Meling TwinDrive freezers meet ENERGY STAR V2.0 standards, consuming less power while maintaining ultra-low cooling. Advanced VIP vacuum insulation panels further reduce energy demand, while eco-friendly HC refrigerants align with sustainability goals.

User-focused design includes a 10″ intelligent touch screen, ergonomic handles and comprehensive alarm systems for monitoring. Optional CO₂ back-up systems add an extra layer of protection.

Logos Biosystems LUNA-FX7 Automated Cell Counter

Mon, 01 Dec 2025 00:00:00 +1100

Accurate cell counting is critical in research, yet laboratories routinely face several challenges that can compromise results. Manual counting with haemocytometers is slow and subjective, often introducing variability between users and experiments. Complex or heterogeneous samples, such as high-density cultures, clumped cells, debris or mixed populations, make reliable counting difficult and time-consuming. Labs that need to process multiple samples or high-throughput assays often struggle to maintain efficiency without sacrificing accuracy.

The LUNA-FX7 Automated Cell Counter from Logos Biosystems is designed to address all of these issues. Its high-resolution imaging and advanced algorithms can deliver precise and reproducible counts, effectively eliminating the inconsistencies associated with manual methods. The system’s brightfield and fluorescence channels allow for discrimination between live and dead cells, even in challenging or heterogeneous samples.

In addition, the LUNA-FX7 can simultaneously analyse multiple samples with its 1-, 3- and 8-chamber slide options, reducing hands-on time and increasing throughput. Automated focus, exposure and quality-control features enable consistent results across all samples. The intuitive touchscreen interface and software-assisted data management make the system easy to operate while supporting standardised workflows, including regulated laboratory environments.

By streamlining cell counting and removing common sources of error, the LUNA-FX7 empowers researchers to save time, work more efficiently and generate reproducible data.

ATA Scientific offers demonstrations and expert support to help laboratories integrate the LUNA-FX7 into their workflows. To see the benefits for yourself, contact the company today or visit https://www.atascientific.com.au/products/luna-fx7-automated-cell-counter/.

Proteintech CoraLite Plus-Tyramide reagents and detection kits

Mon, 01 Dec 2025 00:00:00 +1100

Proteintech’s CoraLite Plus-Tyramide dyes are fluorescent labelling reagents based on TSA technology. Upon interaction with HRP, the tyramides are oxidised into free radicals, which then allows the dyes to form covalent bonds with nearby tyrosine residues on the antigen of interest.

Compared to indirect staining methods, TSA dyes can enhance the fluorescent signal by several hundred-fold due to dye accumulation and direct labelling of the target. This makes them particularly useful for the detection of low-abundance targets.

Furthermore, this system is suitable for tissue multiplexing as multiple TSA dyes can be sequentially added through cyclical antibody stripping and re-probing.

Other benefits include up to 100x more sensitivity than indirect staining methods, achieving publication-quality data at the first attempt. A wide dynamic range enables the detection of low-abundance targets and easy multiplexing with no limitations on the primary antibody host.

For further information, contact United Bioresearch Products, the distributor of the full range of Proteintech products in Australia, or visit https://www.ptglab.com/products/tyramide-signaling-amplification-reagents/.

Camfil Australia Opakfil ES V-Bank air filter with Works with WELL designation

Wed, 19 Nov 2025 00:00:00 +1100

Camfil Australia has confirmed that its compact V-Bank air filter, Opakfil ES, has successfully maintained its Works with WELL designation. This program, developed by the International WELL Building Institute (IWBI), recognises products that align with WELL strategies based on IWBI licensing criteria. By achieving the Works with WELL trademarks, companies can demonstrate their commitment to advancing products and solutions that support human health and wellbeing.

Opakfil ES continues to meet stringent performance criteria, including: high energy efficiency, as it’s designed to minimise energy consumption, contributing to sustainable building operations; low pressure drop, enabling efficient airflow and reducing strain on HVAC systems; and high dust-holding capacity, extending filter life and reducing maintenance needs. Compliant with ISO 16890, it is available in ePM1 and ePM10 efficiencies, for effective particulate filtration.

These features make the air filter suitable for applications where air quality and energy efficiency are important.

Camfil is now working to further expand its range of WELL-certified solutions.

For more information on Opakfil ES and its designation, visit https://bit.ly/camfilauworkswithwell.

Malvern WAVEsystem (GCI) and PEAQ ITC for detecting weak interactions in drug discovery

Sat, 01 Nov 2025 00:00:00 +1100

Fragment-based drug discovery (FBDD) is a powerful approach in modern drug development. It identifies promising drug candidates by screening small molecular fragments with low molecular weights that bind weakly but specifically to biological targets. However, detecting and characterising these weak interactions presents a significant challenge. Grating-coupled interferometry (GCI) and isothermal titration calorimetry (ITC) have emerged as essential tools for overcoming these hurdles, enabling researchers to validate fragment binding and gain deep kinetic and thermodynamic insights.

The Malvern WAVEsystem uses GCI, an advanced optical technique that provides real-time, label-free detection of molecular interactions. Unlike surface plasmon resonance (SPR), GCI uses waveguide-based interference, enhancing sensitivity for low-affinity fragments that may be missed using other methods. GCI detects weak-binding fragments, measures association and dissociation rates with precision, and enables efficient screening with minimal sample consumption. By identifying fragments with desirable kinetic profiles, GCI acts as a first filter in the FBDD workflow.

While the Malvern WAVEsystem (GCI) excels in kinetics, the Malvern PEAQ ITC provides a thermodynamic profile by measuring the heat released or absorbed during binding. It confirms hits detected by GCI and differentiates enthalpy- and entropy-driven interactions, offering insights into binding mechanisms. ITC also detects non-specific interactions and quantifies absolute binding constants, complementing GCI’s kinetic data.

Individually, the Malvern WAVEsystem (GCI) and Malvern PEAQ ITC are powerful tools, but their combined use offers deep insights into fragment binding. While GCI identifies and ranks hits based on binding kinetics, ITC validates and characterises their thermodynamic properties. This combined data can guide structure-based optimisation, leading to high-affinity, drug-like molecules while reducing time to clinical candidates.

The complementary nature of these techniques means that no valuable fragment is overlooked and all critical binding characteristics are fully explored, making them useful tools for modern drug development.

To learn more or book your personal demo, contact ATA Scientific or visit https://www.atascientific.com.au/products/creoptix-wave/.