Comments for Lab Science News

Comment on USP 467 for Residual Solvents: Manufacturers Face Challenges with Pharmaceutical Impurities by Julie

Julie — Tue, 07 Feb 2012 06:53:50 +0000

Dear Sir/Madam,
Could you advise what is the concentration limit allowed in API (active pharmaceutical ingredient) for o-xylene? Is there any guideline for it?

Thank you very much.

Regards,
Juliani

Comment on EPA Study Eases Concern of Harmful Chemicals Being Found in Playground Surfaces by Amy Stephan

Amy Stephan — Sat, 28 Jan 2012 18:13:21 +0000

Wondering what became of the Spring 2010 EPA meeting that is referenced above? Can you let me know if there was a meeting or report?

Also, why is carbon black not on the list above, as it comprises over 30% of the material in tires? I noticed it is missing from the EPA list of tire ingredients as well.

Thanks for responding back to me.

Amy

Comment on USP 467 for Residual Solvents: Manufacturers Face Challenges with Pharmaceutical Impurities by Pervaiz Qureshi

Pervaiz Qureshi — Thu, 26 Jan 2012 19:49:53 +0000

Dear Dr. Kalakoti,
Here is the answer to your question.
The ppm limits for all Class 3 solvents as per USP is 5000, and the PDE (Permitted Daily Exposure) is >50 mg/day. Is it clear?

Comment on Cadmium Exposure and Testing by Payton Gary

Payton Gary — Wed, 25 Jan 2012 21:01:09 +0000

Hello, my name is Payton,

I’ve been looking for an expert on cadmium as I have a few questions. I am from Stambaugh Middle School in the United States, and I am on the school’s Robotics team. We have a robotics competition coming up in which we are required to complete a research project on food contamination. Our topic is Cadmium in rice. We’ve decided to ask you a few questions since you seem to have an expertise that no one else possesses on the matter.

1. Is Cadmium magnetic?

2. Can Cadmium be evaporated and/or washed out of rice? Is it easy or difficult?

3. Has Cadmium been a serious problem lately? Within the past 5 years?

4. We’ve created a solution which consists of this: “an assembly line machine that with run large tubs of rice through a filter/washing station onto a conveyer belt that will heat the rice causing any infected water to evaporate, it will repeat this process about 3 times. Every 10 tubs will also be sampled for Cadmium.” Does this solution sound plausible to you?

Thank you for your time,
-Payton Gary

Comment on Cadmium Exposure and Testing by admin

admin — Fri, 20 Jan 2012 23:00:24 +0000

Hi Valerie,

I would suggest that you discuss your potential exposure with your doctor. I know of no testing kit on the market that would allow you to test for the levels of cadmium needed to ensure your materials do not pose health risks. To ensure your zinc alloy does not include cadmium, you may want to purchase it from a vendor that can provide a certificate that it is cadmium-free. If they are reputable, they will have such a certificate. Thanks,

Dee O’Neill
ALS-Columbia

Comment on Allowable Levels Established for DEHP in Bottled Water by admin

admin — Fri, 20 Jan 2012 22:46:41 +0000

Hello! You will want to contact Nestle directly to find out what tests they perform on their bottled water and what safety standards they adhere to.

Comment on Allowable Levels Established for DEHP in Bottled Water by Manny Gonzales

Manny Gonzales — Fri, 20 Jan 2012 20:59:24 +0000

My question is: How safe is the bottled water Nestle Pure Life 16.9FLOZ (500mL)? Is it within safety standards?

Comment on USP 467 for Residual Solvents: Manufacturers Face Challenges with Pharmaceutical Impurities by admin

admin — Thu, 19 Jan 2012 18:30:34 +0000

Hello Rajesh,

Tert-butanol is not listed in the USP <467> method, so we cannot provide a limit.

Thank you,

Columbia Analytical Services, Inc.
Now part of the ALS group

Comment on USP 467 for Residual Solvents: Manufacturers Face Challenges with Pharmaceutical Impurities by Rajesh Pawar

Rajesh Pawar — Wed, 18 Jan 2012 06:23:08 +0000

What is residual solvent of Tert-butanol limit in API

Comment on Cadmium Exposure and Testing by Valerie K

Valerie K — Sat, 14 Jan 2012 19:25:12 +0000

I am a jewelry maker as a hobby and I often purchase metal alloy (zinc) beads directly from China. I have recently learned of the dangers of Cadmium. Can you recommend a good testing kit/method to test the inventory I have on hand, and also tell me what the ‘acceptable levels’ of cadmium are for such use as jewelry making. My items are not used by children, so I am assuming there is no ingestion of the beads, just the normal wear. I am concerned about my continued exposure to the materials however.

Thank you,

Valerie K.