Mission pour la Science et la Technologie de l'Ambassade de France aux Etats-Unis

The 2nd ICPerMed Conference 'Personalised Medicine - From Vision to Practice'

FranÃ§ois D — 2020-04-10T18:04:33Z

Supported by the European Commission, the conference will bring together world's leading researchers, ELSI experts, health economists, payers, patients and industry representatives, regulatory authorities and HTA experts and ICPerMed members including ministries representatives, research funding and policy organisations.
Within the last years, ICPerMed gathered and analysed needs from relevant stakeholders, defining challenges and actionable levers. In this context, ICPerMed developed a Vision Paper focusing on five challenges or perspectives in personalised medicine:

• Citizen engagement,
• Involvement of health providers,
• Implementation within healthcare systems,
• Health-related information,
• Economic value of implementation.

In the Vision Paper, ICPerMed provides keys on how to cross personalised medicine barriers through essential and transversal pillars that will allow improved therapy, diagnostic and preventive approaches, as well as new healthcare concepts for the benefit of citizens and patients.

During the conference, ICPerMed will be committed to demonstrate the importance and the need to address personalised medicine challenges through the prism of these critical pillars focusing on data & technology, intersectoral synergies and education & literacy necessary to initiate the translation into healthcare systems. To this end, the conference will comprise keynote lectures focusing on the implementation of personalised medicine approaches into healthcare systems for the benefit of patients, citizens and the society as a whole. In addition, in a specific dedicated session, ICPerMed will feature and honour best practices in personalised medicine research through the ICPerMed Recognition 2020, that aims to recognise, encourage, promote and disseminate outstanding examples.

Further information about the conference, the venue and the Scientific Committee Panel are available here:
https://www.icpermed.eu/en/ICPerMed-Conference-2020.php
Please register via the further link:
https://secure.pt-dlr.de/pt-conference/conference/ICPerMed_Okt_20
For further information about the conference, please contact ICPerMed@agencerecherche.fr

About ICPerMed

ICPerMed provides a platform to initiate and support communication and exchange on personalised medicine research, funding and implementation. ICPerMed assembles over 40 European and international partners representing ministries, funding agencies and the European Commission. With the support of the ICPerMed Secretariat, the consortium works on coordinating and supporting research to develop approaches for personalised medicine. Thereby, the central aim of ICPerMed is to align and encourage joint efforts in personalised medicine research and implementation on a European and international level. The ICPerMed Secretariat is coordinated by partners from France, Germany, Italy and Spain.

Postdoctoral position on Cancer and Cell Biology in Nice, France

FranÃ§ois D — 2020-04-08T18:53:48Z

Our team is multidisciplinary with 3 PU-PH, 2 MCU, 2 PH, 4 CNRS or INSERM researchers, 1 postdoc, 5 thesis students, 4 masters, 3 Engineers and technicians to make a direct link between biology and the clinic. Our laboratory is part of IRCAN INSERM U1081 / CNRS 7284 hosted by the Antoine Lacassagne Center for Cancer Research located in Nice, France.

Aging is usually perceived as a process that results from the combined influence of constitutional or so-called « genetic » factors, life-style associated factors and external events. Understanding these multiple interconnections requires synergy between many areas of molecular, cellular or biomedical experimental biology or biology, more dedicated to the study of aging and age-related diseases such as cancer. To this goal, the Institute for Research on Cancer and Aging Nice (IRCAN UMR7284, U1081) was created on January 1st, 2012, by the University of Cote d'Azur (UCA), the National Institute for Health and Medical Research (Inserm), and the National Center for Scientific Research (CNRS). The IRCAN was established to develop a strong research center focusing on cancer and aging, in the Medical School of Nice and in partnership with the cancer “Center Antoine Lacassagne” (CAL) and the Nice University Hospital (CHUN).

The research carried out at the IRCAN involves major areas of biology, from basic research to medical applications, with the objectives of improving our understanding of the common foundation between aging and cancer, and developing innovative strategies to prevent and cure cancer and chronic age-related pathologies.

Our laboratory is made up of about fifteen people and we work in a dynamic and international environment. The candidate will also benefit from the scientific environment (14 teams and around 200 people dedicated to research on cancer and aging) and the technical platforms made available by IRCAN.

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POSITION : The Institute of Pharmacology and Structural recruits

FranÃ§ois D — 2020-04-08T18:44:46Z

The Institute of Pharmacology and Structural Biology (IPBS) and the Centre for Integrative Biology (CBI) in Toulouse have launched a joint call for the recruitment of new group leaders.

IPBS and CBI are leading research institutes of the French National Centre for Scientific Research (CNRS) and the University of Toulouse, respectively founded in 1996 and 2016. They are located in Toulouse, southwest France, on the main Campus of the Université Toulouse III-Paul Sabatier, offering multidisciplinary education in the fields of Science, Health, Engineering and Technology, and developing one of the most important scientific research clusters in France.

The CBI-Toulouse conducts internationally recognized research in in fundamental aspects of the structure and function of complex biological systems. Research at CBI covers all scales from individual molecules to the whole organism, groups and animal societies. It is multidisciplinary, combining a wide range of research fields from genetics, epigenetics and RNA biology to microbiology, cell biology, chromatin / chromosome dynamics, developmental biology, neurobiology, collective animal behavior, as well as computational and systems biology.

The IPBS-Toulouse is a world leader in the discovery, characterization and validation of novel pathways and pharmacological targets in the fields of cancer, infection and inflammation, through the use of molecular and cellular biology approaches, together with in vivo experiments. It conducts state-of-the-art research in cancerology, immunology, microbiology, structural biology, proteomics, and biophysics.

The two institutes bring together more than 650 scientists and supporting staffs, including more than 100 national and international postdoctoral fellows and PhD students, in 57 research groups. They offer an outstanding scientific and stimulating research environment and several cutting-edge core facilities with highly qualified staff. These include mass spectrometry and proteomics, macromolecular crystallography, electron microscopy with cryoEM, liquid- and solid-state NMR, biophysical characterization of proteins and complexes, virtual screening, single particle tracking and tethered particle motion analysis, whole body, tissue and cellular imaging, flow cytometry and cell sorting in standard or BSL3 laboratories and animal facilities (housing bees, Drosophila, zebrafish, Xenopus and mice), together with a computer cluster for large data analysis and simulation.

In order to reinforce their research endeavors in an inspiring, collaborative and cutting-edge environment, the IPBS and the CBI are seeking new talented group leaders addressing fundamental questions, with priority on :

1) MICROBIOLOGY, including

· Infection biology : Biology of bacterial pathogens, with a particular focus on respiratory pathogens, addressing the mechanisms underlying pathogens' virulence and host-pathogen interactions, pathogens' persistence, drug resistance or tolerance within the host.

· Quantitative and computational biology of microbes : Applied to all aspects of bacteria, archaea, unicellular eukaryotes and their virus's biology

· Integrative structural biology of microbes : Applications based on structure determination by cryo-EM and cryo-electron tomography are encouraged.

https://www.nature.com/naturecareers/job/new-group-leaders-in-microbiology-and-infection-biology-center-for-integrative-biology-in-toulouse-cbi-toulouse-723024

2) CANCER BIOLOGY, including

• Tumor microenvironment /Cancer immunology : Implication of stromal components (immune and other cells) and extra-cellular matrix in tumor progression ; metabolic landscape of the tumor microenvironment ; targeting microenvironment for cancer therapy (including immunotherapy)

• DNA repair in cancer with therapeutic connections : DNA damage response (DDR) in cancer (epigenetics, transcriptional regulation, DNA repair syndroms, chromosomal translocations) and DDR-targeted drug discovery, or tumor resistance and/or vulnerabilities to clastogenic agents and/or DDR modulation.

https://www.nature.com/naturecareers/job/new-group-leaders-in-cancer-biology-institute-of-pharmacology-and-structural-biology-ipbs-723025

3) CELLULAR AND DEVELOPMENTAL BIOLOGY, with complementary expertise to existing groups investigating numerous aspects from cell division, morphogenesis to progenitor/stem cell biology using model organisms. Candidates complementing or reinforcing this community are encouraged to apply. Particular attention will be given to interdisciplinary, experimental and/or theoretical projects encompassing biophysics, systems biology and/or computational approaches.

https://www.nature.com/naturecareers/job/new-group-leaders-in-cellular-and-developmental-biology-center-for-integrative-biology-in-toulouse-cbi-toulouse-723020

Successful candidates will be provided with office and lab space for 5-10 people, staff support, a financial starting package and free access to technological facilities of both institutes.

Outstanding candidates, of any nationality at early-career stage, are expected to develop competitive, independent research and meet the required criteria for successful application to national and international funding, including ATIP-Avenir, FRM, ANR “Jeunes Chercheurs-euses”, ERC-StG or CoG, or equivalent installation grant, and to a position at CNRS. Senior researchers holding a CNRS or University position are also welcome to apply.

Tentative calendar

Applications (about 10 pages, in English) should be sent before May 12, 2020

Mid-June : Preselection of candidates.

Mid-July : Interview of preselected candidates by the selection committee and presentation of planned research projects

End-July : Outcome of the selection process.

The IPBS-Toulouse (France) recruits - New Group leaders in Cancer Biology

The IPBS and CBI (Toulouse, France) recruit New Group leaders in Microbiology and Infection Biology

Junior group leader in Cellular and Developmental Biology

MASTER - Computational Neuroscience and Neuroengineering.

FranÃ§ois D — 2020-03-09T19:16:43Z

A new Master Degree in "Computational Neuroscience and Neuroengineering (CNN)" is opening in 2020 at the Université Paris-Saclay together with CentraleSupélec School.

The Computational Neurosciences and Neuroengineering Master will train students in the fields of perception, processing and transmission of neural information, closed-loop neuroscience, control theory applied to the neurosciences and other related topics (see the flyer). The training program is based on experimental, computational and theoretical approaches, combining neurosciences, physics, applied mathematics, computer sciences and engineering at different scales (cell, network, behaviour) and different organizational levels (micro, meso- and macroscopic scales).

The application website is now open : https://inception.universite-paris-saclay.fr/en/

It is also possible to apply for a scholarship at : https://www.universite-paris-saclay.fr/en/admission/scholarships-and-financial-aid/bourses-internationales-de-master/international-masters

If more information is needed, please contact Sabir Jacquir at (sabir.jacquir@u-psud.fr).

Recherche Position : Maître de conférences

FranÃ§ois D — 2020-03-06T16:43:20Z

The Department of Bioengineering offers courses for engineering students at the bachelor's, master's and PhD levels. It hosts the Biomechanics and Bioengineering (UMR CNRS 7338) and Enzyme and Cell Engineering (UMR CNRS 7025) research laboratories. There are modules (part of the UTC Common Core) for entry-level
undergraduates, as well as specialized majors within the Engineering curriculum and at the master's level. The Department maintains strong connections with industry in teaching as well as in research, and has built close links with academic institutions and partners internationally. Over the course of three years, Engineering students enrolled at the Department of Bioengineering acquire knowledge and skills in both engineering and life sciences to prepare them for a career in agrifood,
biotechnology, or in the biomedical area.

- Open Calls for Proposals / actualite, actualite_offre

Fondation Alzheimer: Call for Applications

Carrina LaCorata — 2020-02-26T15:17:57Z

For the second consecutive year, the Fondation Alzheimer and the Fondation de France are partnering to allow young scientific or medical researchers who have already participated in mobility to continue their research works on the Alzheimer disease in a French laboratory with the aim of strengthening their professional development in preparation of a future permanent academic position. The granted funding is intended to cover the recipient's salary.

You have until May 11, 2020 to send your application for the Young Researchers Allocation in English via email and mail to the Fondation Alzheimer.

For more information and to download the documents,,
http://www.fondation-alzheimer.org

POSITION : Applications for junior or senior group leaders

FranÃ§ois D — 2020-02-24T16:13:29Z

The CRI is opening a call for group leaders or established teams with expertise in inflammatory diseases and/or inflammation-driven fibrosis and cancer

- Open Calls for Proposals / actualite, actualite_offre

Post Doc Fellow - Stem Cells Gene Therapy/Gene editing for inherited disorders

FranÃ§ois D — 2020-02-03T17:10:52Z

Lab/Research Program Website
https://medschool.Friedreich's ataxiaucsd.edu/som/pediatrics/research/labs/cherqui/Pages/default.aspx

About the Position
Title of the Position
Postdoctoral fellow

Job Description
Post Doc Fellow - Stem Cells Gene Therapy/Gene editing for inherited disorders

Location
University of California, San Diego
Department of Pediatrics

Principal Investigator
Stephanie Cherqui, PhD

Disciplinary Specialty of Research
Gene therapy, Gene editing, Stem Cells, Neuroscience

Description of the Position
Available immediately for highly motivated Ph.Ds, the position focuses on the use of hematopoietic stem cells (HSCs) and gene therapy for the treatment of inherited approaches for multi-systemic degenerative disorders, and in particular neuromuscular diseases. Gene therapy technologies employed in the project include lentivirus vectors and CRISPR/Cas9-mediated gene editing. The candidate will also use human and mouse HSCs in in vitro assays and murine models of genetic disorders. The project also includes the investigation of the mechanism involved in the rescue of degenerative neuromuscular tissues by HSC-derived cells. Successful Candidates will be part of a stimulating and collaborative scientific environment with cutting-edge instrumentation and facilities.

Qualifications Required and Preferred Academic Background
The candidate should be highly self-motivated, with strong communication and interpersonal skills and the ability to work independently, has a PhD, with a strong background in stem cell biology, gene therapy and CRISPR/Cas9-mediated gene editing and neuroscience. Experience with mice is required.
If you are interested, please submit your C.V. to Stephanie Cherqui scherqui@ucsd.edu.

Salary/Stipend
Salary is commensurate with experience.

Appointment Length/Period
Two years, with possibility for extension.

Call for applications 2020 - International mobility of junior researchers in Pediatric Cancers

FranÃ§ois D — 2020-01-29T20:08:59Z

The French Government has recently reinforced its commitment to pediatric cancer research through an additional annual 5M € plan coordinated by INCa, in conjunction with French research organizations (AVIESAN), public and private operators in oncology, healthcare professionals, health service users and voluntary bodies, including parents' associations. This new funding, repeated in 2020, reinforces the efforts of the French government, which has made research in paediatric oncology a priority. In this context, a call for proposals has been opened to enhance the attractiveness of pediatric oncology research for young talents and facilitate their career in pediatric oncology research.

- Open Calls for Proposals / actualite, actualite_offre, Sciences de la vie

GROUP LEADER POSITION

FranÃ§ois D — 2020-01-23T17:18:55Z

The Mediterranean Institute of Neurobiology (INMED), an internationally renowned Neuroscience Research Center with a long tradition of outstanding research, is seeking to recruit new independent group leaders in all fields of neuroscience. The institute currently hosts 9 research teams (150 people) engaging with a strong cooperative spirit in several fields of neuroscience including physiological and pathological neurodevelopment, neuronal
signaling, neural circuits, synapse biology, memory, spatial cognition, motor and sensory functions and various psychiatric and neurological diseases models (epilepsy, addiction, autism).

- Open Calls for Proposals / actualite_offre