Nature Biotechnology is a monthly journal publishing new concepts in biological technology of relevance to bioengineering, medicine, energy, agriculture, food and the environment. It has a magazine covering the commercial, political, ethical, legal and societal aspects of this research. http://feeds.nature.com/nbt/rss/current Nature Publishing Group en © 2026 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Nature Biotechnology © 2026 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. permissions@nature.com https://www.nature.com/uploads/product/nbt/rss.png http://feeds.nature.com/nbt/rss/current https://www.nature.com/articles/s41587-026-03225-x Nature Biotechnology, Published online: 16 July 2026; doi:10.1038/s41587-026-03225-x

Each year, Nature Biotechnology highlights companies that received sizeable early-stage funding in the previous year. Stylus Medicine is engineering novel recombinases for in vivo CAR T cell cancer therapy.]]> Ken Garber doi:10.1038/s41587-026-03225-x Nature Biotechnology, Published online: 2026-07-16; | doi:10.1038/s41587-026-03225-x 2026-07-16 Nature Biotechnology 10.1038/s41587-026-03225-x https://www.nature.com/articles/s41587-026-03225-x https://www.nature.com/articles/s41587-026-03248-4 Nature Biotechnology, Published online: 16 July 2026; doi:10.1038/s41587-026-03248-4

J. Craig Venter 1946–2026]]> Barry Merriman doi:10.1038/s41587-026-03248-4 Nature Biotechnology, Published online: 2026-07-16; | doi:10.1038/s41587-026-03248-4 2026-07-16 Nature Biotechnology 10.1038/s41587-026-03248-4 https://www.nature.com/articles/s41587-026-03248-4 https://www.nature.com/articles/s41587-026-03228-8 Nature Biotechnology, Published online: 15 July 2026; doi:10.1038/s41587-026-03228-8

Adenosine deaminases acting on RNA (ADARs) have not been previously exploited for DNA adenine base editing in mammals. We developed a single-nucleotide-resolution adenine base editor (snuABE) that uses ADAR and customized guide RNAs to precisely convert adenines to guanines on DNA targets with minimal bystander editing.]]> doi:10.1038/s41587-026-03228-8 Nature Biotechnology, Published online: 2026-07-15; | doi:10.1038/s41587-026-03228-8 2026-07-15 Nature Biotechnology 10.1038/s41587-026-03228-8 https://www.nature.com/articles/s41587-026-03228-8 https://www.nature.com/articles/s41587-026-03184-3 Nature Biotechnology, Published online: 15 July 2026; doi:10.1038/s41587-026-03184-3

Tumors are imaged across scales—from cells to whole body—with a triple-reporter mouse.]]> Ximena L. Raffo-IraolagoitiaAbdullah AlyamaniStephanie MayDavid StevensonAgata MackintoshLynn McGarryJayanthi AnandDmitry SolovievGavin BrownColin NixonChrysa KapeniMaike De La RocheKaren BlythThomas Graham BirdDouglas StrathdeeScott K. LyonsGilbert FruhwirthLeo M. CarlinDavid Y. Lewis doi:10.1038/s41587-026-03184-3 Nature Biotechnology, Published online: 2026-07-15; | doi:10.1038/s41587-026-03184-3 2026-07-15 Nature Biotechnology 10.1038/s41587-026-03184-3 https://www.nature.com/articles/s41587-026-03184-3 https://www.nature.com/articles/s41587-026-03231-z Nature Biotechnology, Published online: 15 July 2026; doi:10.1038/s41587-026-03231-z

Volumetric mesoscale imaging reveals subcellular immune dynamics in different mammalian organs.]]> Zhi LuMinghuan WangWentao ChenManchang JinLaiyu ZhuTianyun WangQi ZhangYi YangChaowei ZhuangJiamin WuWei WangQionghai Dai doi:10.1038/s41587-026-03231-z Nature Biotechnology, Published online: 2026-07-15; | doi:10.1038/s41587-026-03231-z 2026-07-15 Nature Biotechnology 10.1038/s41587-026-03231-z https://www.nature.com/articles/s41587-026-03231-z https://www.nature.com/articles/s41587-026-03222-0 Nature Biotechnology, Published online: 15 July 2026; doi:10.1038/s41587-026-03222-0

Event-based first-photon fluorescence lifetime imaging enables fluorescence lifetime imaging below one photon per pixel.]]> Yiliang ZhouYihong XiaoJing ZhouBo LiuZhifeng ZhaoXinyang LiMinghuan WangJiamin WuQionghai Dai doi:10.1038/s41587-026-03222-0 Nature Biotechnology, Published online: 2026-07-15; | doi:10.1038/s41587-026-03222-0 2026-07-15 Nature Biotechnology 10.1038/s41587-026-03222-0 https://www.nature.com/articles/s41587-026-03222-0 https://www.nature.com/articles/s41587-026-03232-y Nature Biotechnology, Published online: 14 July 2026; doi:10.1038/s41587-026-03232-y

Biotech news from around the world]]> doi:10.1038/s41587-026-03232-y Nature Biotechnology, Published online: 2026-07-14; | doi:10.1038/s41587-026-03232-y 2026-07-14 Nature Biotechnology 10.1038/s41587-026-03232-y https://www.nature.com/articles/s41587-026-03232-y https://www.nature.com/articles/s41587-026-03244-8 Nature Biotechnology, Published online: 14 July 2026; doi:10.1038/s41587-026-03244-8

MHRA’s radical rare disease proposal]]> doi:10.1038/s41587-026-03244-8 Nature Biotechnology, Published online: 2026-07-14; | doi:10.1038/s41587-026-03244-8 2026-07-14 Nature Biotechnology 10.1038/s41587-026-03244-8 https://www.nature.com/articles/s41587-026-03244-8