Nature Reviews Neuroscience is the leading review journal in the neurosciences. It publishes articles that review recent progress in brain and nervous system research. Topics range from molecular and cellular aspects of neuronal development and function to behavior, cognition and disorders of the nervous system. By commissioning the best authors to write on the timeliest issues, and following a rigorous peer-review process, the journal provides an unparalleled source of information and opinion for neuroscientists in academia, clinical research and industry. One of the unique features of Nature Reviews Neuroscience is its extraordinary breadth and depth of coverage. This very broad scope – from molecules to mind – captures the essence of modern neuroscience, and allows the journal to attract readers from all areas of this ever-expanding discipline. http://feeds.nature.com/nrn/rss/current Nature Publishing Group en © 2026 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Nature Reviews Neuroscience © 2026 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. permissions@nature.com https://www.nature.com/uploads/product/nrn/rss.gif http://feeds.nature.com/nrn/rss/current https://www.nature.com/articles/s41583-026-01086-6 Nature Reviews Neuroscience, Published online: 24 September 2026; doi:10.1038/s41583-026-01086-6

Human brain organoids cultured for more than 5 years reproduce endogenous programmes of postnatal brain maturation and track the passage of time in culture.]]> Katherine Whalley doi:10.1038/s41583-026-01086-6 Nature Reviews Neuroscience, Published online: 2026-09-24; | doi:10.1038/s41583-026-01086-6 2026-09-24 Nature Reviews Neuroscience 10.1038/s41583-026-01086-6 https://www.nature.com/articles/s41583-026-01086-6 https://www.nature.com/articles/s41583-026-01087-5 Nature Reviews Neuroscience, Published online: 24 September 2026; doi:10.1038/s41583-026-01087-5

Human brain activity under psilocybin contains latent temporal structure that improves alignment with ongoing context and covaries with the subjective quality of the psychedelic experience.]]> Jake Rogers doi:10.1038/s41583-026-01087-5 Nature Reviews Neuroscience, Published online: 2026-09-24; | doi:10.1038/s41583-026-01087-5 2026-09-24 Nature Reviews Neuroscience 10.1038/s41583-026-01087-5 https://www.nature.com/articles/s41583-026-01087-5 https://www.nature.com/articles/s41583-026-01083-9 Nature Reviews Neuroscience, Published online: 24 September 2026; doi:10.1038/s41583-026-01083-9

Some of the least understood phenomena in the brain emerge from interactions between local and global brain states, yet representing their joint activity is a considerable computational challenge. As neuroscience datasets grow and classical methods reach their limits, alternative approaches are needed. Quantum computing, through its novel approach to information processing, may offer a solution.]]> Annemarie WolffAlexandre ChoquetteGeorg NorthoffAtsushi IrikiGuillaume Dumas doi:10.1038/s41583-026-01083-9 Nature Reviews Neuroscience, Published online: 2026-09-24; | doi:10.1038/s41583-026-01083-9 2026-09-24 Nature Reviews Neuroscience 10.1038/s41583-026-01083-9 https://www.nature.com/articles/s41583-026-01083-9 https://www.nature.com/articles/s41583-026-01081-x Nature Reviews Neuroscience, Published online: 16 September 2026; doi:10.1038/s41583-026-01081-x

The capacity to self-evaluate and control one’s own cognitive performance, known as metacognition, underpins adaptive learning, social behaviours and self-belief. Stephen Fleming outlines our current understanding of the neural basis of metacognition, its contributions to self-regulation and social communication, and the consequences of its dysfunction in clinical conditions.]]> Stephen M. Fleming doi:10.1038/s41583-026-01081-x Nature Reviews Neuroscience, Published online: 2026-09-16; | doi:10.1038/s41583-026-01081-x 2026-09-16 Nature Reviews Neuroscience 10.1038/s41583-026-01081-x https://www.nature.com/articles/s41583-026-01081-x https://www.nature.com/articles/s41583-026-01082-w Nature Reviews Neuroscience, Published online: 14 September 2026; doi:10.1038/s41583-026-01082-w

In this Journal Club, Yu Qi discusses a 2021 study that reported a brain–computer interface that used neural activity in the motor cortex to decode attempted handwriting in real time.]]> Yu Qi doi:10.1038/s41583-026-01082-w Nature Reviews Neuroscience, Published online: 2026-09-14; | doi:10.1038/s41583-026-01082-w 2026-09-14 Nature Reviews Neuroscience 10.1038/s41583-026-01082-w https://www.nature.com/articles/s41583-026-01082-w https://www.nature.com/articles/s41583-026-01078-6 Nature Reviews Neuroscience, Published online: 11 September 2026; doi:10.1038/s41583-026-01078-6

Recent years have witnessed major advances in our understanding of the distinct functional and computational roles of the ventral hippocampus (vHPC). Mazen Kheirbek and colleagues examine the state-dependent representation of behaviourally salient information by the vHPC and discuss how its anatomy and circuit connectivity support affective and motivational behaviours.]]> Jeremy S. BianeJulian Wagner-CarenaMazen A. Kheirbek doi:10.1038/s41583-026-01078-6 Nature Reviews Neuroscience, Published online: 2026-09-11; | doi:10.1038/s41583-026-01078-6 2026-09-11 Nature Reviews Neuroscience 10.1038/s41583-026-01078-6 https://www.nature.com/articles/s41583-026-01078-6 https://www.nature.com/articles/s41583-026-01080-y Nature Reviews Neuroscience, Published online: 11 September 2026; doi:10.1038/s41583-026-01080-y

The mechanisms underlying electrical transmission are often viewed as relatively simple compared with those mediating chemical transmission, yet electrical synapses exhibit dynamic changes in structure and strength. In this Review, Alberto Pereda and Adam Miller examine the structural and molecular bases and complexities of electrical transmission.]]> Alberto E. PeredaAdam C. Miller doi:10.1038/s41583-026-01080-y Nature Reviews Neuroscience, Published online: 2026-09-11; | doi:10.1038/s41583-026-01080-y 2026-09-11 Nature Reviews Neuroscience 10.1038/s41583-026-01080-y https://www.nature.com/articles/s41583-026-01080-y https://www.nature.com/articles/s41583-026-01077-7 Nature Reviews Neuroscience, Published online: 28 August 2026; doi:10.1038/s41583-026-01077-7

A new study reports that olfactory receptor genes in the mosquito Aedes aegypti can be coexpressed in olfactory neurons and expressed in multiple subtypes of these neurons.]]> Darran Yates doi:10.1038/s41583-026-01077-7 Nature Reviews Neuroscience, Published online: 2026-08-28; | doi:10.1038/s41583-026-01077-7 2026-08-28 Nature Reviews Neuroscience 10.1038/s41583-026-01077-7 https://www.nature.com/articles/s41583-026-01077-7