Nature Reviews Neuroscience is the leading review journal in the neurosciences. It publishes articles that review recent progress in brain and nervous system research. Topics range from molecular and cellular aspects of neuronal development and function to behavior, cognition and disorders of the nervous system. By commissioning the best authors to write on the timeliest issues, and following a rigorous peer-review process, the journal provides an unparalleled source of information and opinion for neuroscientists in academia, clinical research and industry. One of the unique features of Nature Reviews Neuroscience is its extraordinary breadth and depth of coverage. This very broad scope – from molecules to mind – captures the essence of modern neuroscience, and allows the journal to attract readers from all areas of this ever-expanding discipline. http://feeds.nature.com/nrn/rss/current Nature Publishing Group en © 2026 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Nature Reviews Neuroscience © 2026 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. permissions@nature.com https://www.nature.com/uploads/product/nrn/rss.gif http://feeds.nature.com/nrn/rss/current https://www.nature.com/articles/s41583-026-01082-w Nature Reviews Neuroscience, Published online: 14 September 2026; doi:10.1038/s41583-026-01082-w

In this Journal Club, Yu Qi discusses a 2021 study that reported a brain–computer interface that used neural activity in the motor cortex to decode attempted handwriting in real time.]]> Yu Qi doi:10.1038/s41583-026-01082-w Nature Reviews Neuroscience, Published online: 2026-09-14; | doi:10.1038/s41583-026-01082-w 2026-09-14 Nature Reviews Neuroscience 10.1038/s41583-026-01082-w https://www.nature.com/articles/s41583-026-01082-w https://www.nature.com/articles/s41583-026-01078-6 Nature Reviews Neuroscience, Published online: 11 September 2026; doi:10.1038/s41583-026-01078-6

Recent years have witnessed major advances in our understanding of the distinct functional and computational roles of the ventral hippocampus (vHPC). Mazen Kheirbek and colleagues examine the state-dependent representation of behaviourally salient information by the vHPC and discuss how its anatomy and circuit connectivity support affective and motivational behaviours.]]> Jeremy S. BianeJulian Wagner-CarenaMazen A. Kheirbek doi:10.1038/s41583-026-01078-6 Nature Reviews Neuroscience, Published online: 2026-09-11; | doi:10.1038/s41583-026-01078-6 2026-09-11 Nature Reviews Neuroscience 10.1038/s41583-026-01078-6 https://www.nature.com/articles/s41583-026-01078-6 https://www.nature.com/articles/s41583-026-01080-y Nature Reviews Neuroscience, Published online: 11 September 2026; doi:10.1038/s41583-026-01080-y

The mechanisms underlying electrical transmission are often viewed as relatively simple compared with those mediating chemical transmission, yet electrical synapses exhibit dynamic changes in structure and strength. In this Review, Alberto Pereda and Adam Miller examine the structural and molecular bases and complexities of electrical transmission.]]> Alberto E. PeredaAdam C. Miller doi:10.1038/s41583-026-01080-y Nature Reviews Neuroscience, Published online: 2026-09-11; | doi:10.1038/s41583-026-01080-y 2026-09-11 Nature Reviews Neuroscience 10.1038/s41583-026-01080-y https://www.nature.com/articles/s41583-026-01080-y https://www.nature.com/articles/s41583-026-01077-7 Nature Reviews Neuroscience, Published online: 28 August 2026; doi:10.1038/s41583-026-01077-7

A new study reports that olfactory receptor genes in the mosquito Aedes aegypti can be coexpressed in olfactory neurons and expressed in multiple subtypes of these neurons.]]> Darran Yates doi:10.1038/s41583-026-01077-7 Nature Reviews Neuroscience, Published online: 2026-08-28; | doi:10.1038/s41583-026-01077-7 2026-08-28 Nature Reviews Neuroscience 10.1038/s41583-026-01077-7 https://www.nature.com/articles/s41583-026-01077-7 https://www.nature.com/articles/s41583-026-01070-0 Nature Reviews Neuroscience, Published online: 28 August 2026; doi:10.1038/s41583-026-01070-0

Neural network models can express computational hypotheses about brain information processing, but their high parametric capacity makes discriminating model alignment to experimental data challenging. In this Review, Kriegeskorte and colleagues discuss methodology for the optimization of stimuli that make models disagree in their predictions of neural and behavioural data and enhance model comparison.]]> Tal GolanHeiko H. SchüttNikolaus Kriegeskorte doi:10.1038/s41583-026-01070-0 Nature Reviews Neuroscience, Published online: 2026-08-28; | doi:10.1038/s41583-026-01070-0 2026-08-28 Nature Reviews Neuroscience 10.1038/s41583-026-01070-0 https://www.nature.com/articles/s41583-026-01070-0 https://www.nature.com/articles/s41583-026-01079-5 Nature Reviews Neuroscience, Published online: 27 August 2026; doi:10.1038/s41583-026-01079-5

Injury to hand nerves can lead to disordered digit representation, which is now shown to arise as a result of altered peripheral inputs following nerve regeneration.]]> Sian Lewis doi:10.1038/s41583-026-01079-5 Nature Reviews Neuroscience, Published online: 2026-08-27; | doi:10.1038/s41583-026-01079-5 2026-08-27 Nature Reviews Neuroscience 10.1038/s41583-026-01079-5 https://www.nature.com/articles/s41583-026-01079-5 https://www.nature.com/articles/s41583-026-01076-8 Nature Reviews Neuroscience, Published online: 27 August 2026; doi:10.1038/s41583-026-01076-8

Humans learn the extent to which outcomes are causally attributable to performance through dorsomedial prefrontal cortex tracking decision confidence to estimate the level of control in an environment as well as controllability changes via its interactions with the dorsal raphe nucleus.]]> Jake Rogers doi:10.1038/s41583-026-01076-8 Nature Reviews Neuroscience, Published online: 2026-08-27; | doi:10.1038/s41583-026-01076-8 2026-08-27 Nature Reviews Neuroscience 10.1038/s41583-026-01076-8 https://www.nature.com/articles/s41583-026-01076-8 https://www.nature.com/articles/s41583-026-01075-9 Nature Reviews Neuroscience, Published online: 21 August 2026; doi:10.1038/s41583-026-01075-9

Early-life exposure to stressors can lead to increased stress susceptibility in later life, shown here to be mediated in mice by SETD7-mediated monomethylation of H3K4 in dopaminergic neurons of the ventral tegmental area.]]> Sian Lewis doi:10.1038/s41583-026-01075-9 Nature Reviews Neuroscience, Published online: 2026-08-21; | doi:10.1038/s41583-026-01075-9 2026-08-21 Nature Reviews Neuroscience 10.1038/s41583-026-01075-9 https://www.nature.com/articles/s41583-026-01075-9