http://www.genome.gov/10000475 Press Releases from the National Human Genome Research Institute en-us Thu, 12 Jan 2012 10:42:37 EST Subscribe with My Yahoo!Subscribe with NewsGatorSubscribe with My AOLSubscribe with BloglinesSubscribe with NetvibesSubscribe with GoogleSubscribe with PageflakesSubscribe with Live.com http://www.genome.gov/27546652 http://www.genome.gov/27546652 Investigators at the National Institutes of Health have identified a genetic mutation in three unrelated families that causes a rare immune disorder characterized by excessive and impaired immune function. Symptoms of this condition include immune deficiency, autoimmunity, inflammatory skin disorders and cold-induced hives, a condition known as cold urticaria. The study was led by Joshua Milner, M.D., in the Laboratory of Allergic Diseases at the National Institute of Allergy and Infectious Diseases (NIAID), and Daniel Kastner, M.D., Ph.D., scientific director at the National Human Genome Research Institute (NHGRI). It appears in the online edition of the <em>New England Journal of Medicine</em> on Jan. 11, 2012.<div class="feedflare"> <a href="http://feeds.feedburner.com/~ff/NhgriPressReleases?a=b1ILFyswAJg:CkrLT4nT-Qo:yIl2AUoC8zA"><img src="http://feeds.feedburner.com/~ff/NhgriPressReleases?d=yIl2AUoC8zA" border="0"></img></a> <a href="http://feeds.feedburner.com/~ff/NhgriPressReleases?a=b1ILFyswAJg:CkrLT4nT-Qo:V_sGLiPBpWU"><img src="http://feeds.feedburner.com/~ff/NhgriPressReleases?i=b1ILFyswAJg:CkrLT4nT-Qo:V_sGLiPBpWU" border="0"></img></a> </div><img src="http://feeds.feedburner.com/~r/NhgriPressReleases/~4/b1ILFyswAJg" height="1" width="1"/> Wed, 11 Jan 2012 12:00:00 EST