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In the Feb 23, 2004 edition of the Time Magazine, it was stated

” As scientists delve deeper into the fundamental causes of illnesses, they are starting to see links to an age-old immunological defense mechanism called inflammation.. Hardly a week goes by without the publication of yet another study uncovering a new way that chronic inflammation does harm to the body.”

While scientists have been looking for the perfect anti-inflammatory medicine (it is common knowledge that existing medicines have unwanted side effects), Southeastern Asians were using something natural. People in Southeast Asia have been using the mangosteen fruit for centuries, to maintain their health and cure their ailments.

After a lot of research on the fruit, modern scientists are in close agreement. They’ve found that the fruit has anti-inflammatory abilities, which means it is helpful in preventing and possibly even stopping a wide range of diseases.

The Role of the COX 2 enzyme and Inflammation

When there is inflammation, the pain and swelling is caused by something called prostaglandins. These are made from the COX 2 enzyme. These prostaglandins are sent to an area of injury to help protect it from further injury. However, sometimes the inflammation process overreacts, and sometimes the injury does not fully heal and the inflammation remains at a low level, which results in chronic pain.

Anti-inflammatory drugs work by blocking the action of the COX 1 and COX 2 enzymes. As a result, there are fewer prostaglandins. However, these drugs can cause bleeding problems and stomach irritation because they block COX 1.

The mangosteen is a natural COX 2 inhibitor because of the xanthones found in the pericarp (rind) of the fruit. Many different studies have demonstrated that gamma mangostin, one of the xanthones in mangosteen, dramatically slows down the production of the COX 2 enzyme, which is known to be the major precursor to inflammation. Different researchers did these studies in different laboratories. See 1,2 below.

One study showed that the mangosteen extract was a more potent anti-inflammatory agent than several prescription anti-inflammatory medicines currently used for gout and arthritis.

Further information can be found about this research at the following..
1. Kurzel F, Hagel Ch, Zapf S, Meissneer H, Westphal M. Giese A. Cyclo-oxygenase inhibitors and thromboxane synthase inhibitor differentially regulate migration arrest, growth inhibition and apoptosis in human glioma cells.” Acta Neurochir (Wien). 2002 Jan: 144(1):71-87.

2. Nakatani K, Nakahat N, Arakawa T. Yasuda H. Ohizumi Y. 2001. “Inhibition of cyclooxygenase and prostaglandin E2 synthesis by g-mangostin, a xanthone derivative in mangosteen, in C6 rate glioma cells.” Biochecmical Pharmacology. Volume 63, Issue 1, 1 January 2002, Pages 73-79.

3. Nakatani, K, Arsumi M, Arakawa T, Oosawa k. Shimura S, Nakahata N, Ohizumi Y. “Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant.” Biol Pharm Bull, 2002 Sep: 25(9): 1137-41. Pub Med

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There are numerous healthful benefits in the raw food diet, it will give you increased potassium, magnesium, fiber, foliate and photochemical. This will happen only if your diet is lower in saturated fats, Trans fat and sodium. Not only does the raw food diet claim to offer its users better aiding in digestion, a boost in energy, more improved skin appearance, weight loss, but also help to reduce your risk of heart disease.

Some common utensils used by people on the raw food diet are such as a blender, food processor, juice extractor and a dehydrator. In addition to the foods listed above the person on a raw food diet should not consume three-quarters of their food to over 116 degrees.

Some of the ingredients you find you will need are quite difficult to obtain at your local store, Although it sounds like it would be a breeze in the kitchen as you are not actually cooking your ingredients.

If your normal daily diet consisted of lots of caffeine, meat and or sugar you may experience nausea and headaches throughout your adjustment period in the first few days of your raw food diet.

The raw food diet is sometimes frowned upon from some nutritionists and health professionals because it does lack a nutritional deficit in several areas. Children and pregnant women should steer clear of this diet as well as other individuals with an already weakened or deficit health systems are also advised against the raw food diet.

It is advisable to always check with your primary care physician before starting any diets or exercise programs to see if this is a helpful approach for your body. He will best advise you on the pros and cons of any health regime according to your specific health care needs.
 

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mangosteen satisfies four prerequisites of a superfruit: It’s appealing in taste, fragrance and visually; it’s rich in nutrients; it’s high in antioxidants; and it has the potential to lower risk of disease for people.

The author of the article quotes some research done by Dr. Ray Sahelian, M.D. and summarizes what the xanthones do. You can read the article here

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ONE WAY MANGOSTEEN REDUCES BLOOD SUGAR FOR DIABETICS

SUMMARY:

Mangosteen has been shown, in a recent laboratory study, to slow the breakdown of starch (carbohydrates) to sugar in the same way as the Diabetic drug, Acarbose (Brand names Prandase or Precose). Slower breakdown of starch results in less sugar (glucose) in the blood immediately following eating. Additional studies have shown that Mangosteen is retained in the blood for up to 6 hours maximum effectiveness occurs 1-3 hours after taking Mangosteen.
Thus, Diabetics are recommended to take their Mangosteen 1-3 hours prior to their largest meal, or with this meal. Mangosteen, taken at the correct time will also help non-Diabetics by reducing the extra strain excess sugar puts on the Pancreas. This extra strain on the Pancreas, in time, can lead to Diabetes.

DETAILS:

The Diabetic medication, Acarbose*, works by inhibiting the enzyme (Amylase) that is primarily responsible for the breakdown of Starch to Sugar ( Glucose).

A study** has shown that the one of the Xanthones in the Mangosteen Pericarp works in exactly the same way in our body as Acarbose.

Starch consists of unbranched glucose molecules (Amylose) and branched glucose molecules (Amylopectin). One of the Xanthones in the pericarp of Mangosteen inhibits the enzyme, Amylase. Amylase is inhibited with both Acarbose and Mangosteen, so that the amount of Starch broken down to Sugar from eating is greatly reduced. This means that the sugar level of Diabetics is lessened immediately after a meal. The starch in what was consumed is broken down more slowly over time, after Acarbose and Mangosteen disappear from a person’s blood.

Mangosteen works exactly the same way as Acarbose without any drug side effects.

For Diabetics, the best time to take Mangosteen*** is to take it within 1-3 hrs prior to eating, or with a meal. If a Diabetic is only taking one dose of Mangosteen, they should take their Mangosteen prior to their largest meal.

Non-Diabetics also benefit from taking Mangosteen. This is because diets which contain excess sugar put an unnecessary strain on the Beta cells in the pancreas. Over time, this excess strain has been shown to result in insulin resistance, leading to full blown Diabetes. Taking Mangosteen on a regular basis reduces the amount of sugar in the blood following meals high in carbohydrates and sugars, and thus prevents this strain on the pancreas.

Additional studies **** have shown that Mangosteen is retained in the blood stream for at least 6 hours maximum effectiveness occurs in the first 1-3 hours.

CONCLUSION

Mangosteen and the drug, Acarbose, both result in the slower breakdown of starch to sugar. This leads to everyone having less sugar in their blood following a meal. Less sugar to deal with means it is easier for Diabetics (and non-Diabetics) to move the sugar present in the blood into their cells less insulin needs to be released and the sugar level remains closer to normal. Another benefit of taking Mangosteen versus Acarbose is there are no drug side-effects.

REFERENCES
* Brand Names for Acarbose: Prandase or Precose

** Journal of Agricultural and Food Chemistry 2007 Nov 28; 55(24):9805-10. Assay-guided fractionation study of alpha-amylase inhibitors from Garcina mangostana pericarp.

*** Mangosteen will give one maximum results if it is in liquid form, and also contains Vitamins and Minerals in the same formulation. Mangosteen, minerals, vitamins taken in capsule or tablet form are not readily absorbed and utilized by the body.

**** Brunswick Laboratories 2008. Bioavailability and antioxidant effects of the Vemma formula in humans.

———————–

Vemma contains whole fruit Mangosteen Juice and pericarp extract. Go here for more information and to purchase Vemma Mangosteen Juice

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A raw food diet includes fruit, veggies, sprouts, nuts, seeds, dried fruit and seaweed. These diets are based on eating unprocessed and uncooked plant foods. Raw food advocates believe that heating food above 116 degrees Fahrenheit destroys the enzymes in food that help with digestion and absorption. A typical raw food diet consists of 75% of the diet being raw.

Individuals have sworn that being on the raw food diet increases energy, improves the skin’s appearance and reduces the risk of heart disease. The raw food diet will also help you lose weight and produce better digestion.

Nutritional elements such as potassium, magnesium, fiber, folate and phytochemicals have been associated with lowering the risk of heart disease, cancer and diabetes.

Your body may take some time to get used to the raw food diet, some side effects you may come across are mild headaches, nausea, cravings. This will usually pass in a few days once your body detoxifies.

In your raw food diet you may include foods such as fresh vegetables and fruits, grains, legumes, dried fruit and unprocessed organic or natural foods. You can also include freshly juiced fruits and vegetables, young coconut milk and purified water.

Some equipment you may need to start your raw food diet are a dehydrator which allows you to dehydrate your fruits and vegetables to enjoy whenever you want. Dehydrated food always lasts a lot longer as well.

Also a good food processor or blender will benefit you. It will save you time, not having to chop up your veggies and fruits. Also a good juice extractor is a must have for juicing your fresh fruits and veggies.

This diet may not be beneficial to all people such as children because there growing bodies are in need of more proteins and different nutrients, pregnant or nursing women as they are not to have raw food and also people with anemia or osteoporosis should not consume raw food.

If you are planning on changing your lifestyle and switching to raw food living you must keep in mind that it takes a considerable amount of effort to maintain as all your foods will be made from scratch. Also you may have trouble obtaining some of the ingredients you require. Although if you are committed and do not have any underlying health problems then the raw food way of living may be beneficial to you.

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A few days ago, I was at the market and saw some mangosteens. I had seen them at the market years ago, and never again. These had been imported from Thailand. I bought a couple for Australian $1.50 each. Here’s a picture of the 2 of them.

The lady who sold them to me said to cut the mangosteen in half through the center. Silly me! I cut it all the way through, and a bright red juice started pouring out of the fruit. Then, I realized I wasn’t supposed to cut right through. Anyway, at least you can see all the seeds and the pulp of the fruit in this picture.

I cut the second mangosteen properly by stopping the knife when I got to the soft part. One half of the mangosteen just fell off cleanly, and it looks more like all the other pictures of mangosteen.

I took the white part out carefully, and it consisted of tiny little segments (similar to the segments that an orange has). I really can’t tell you what it tasted like though! It was entirely different to any other fruit I had ever tasted.

A delicious taste! I tasted some of the pericarp (the red part you can see in the hollow section) and it wasn’t nice at all. I’m glad that Vemma has included the pericarp in their Vemma mangosteen juice, and camouflaged the taste.

This photo is the mangosteen next to a passionfruit, just to show you the relative size. This passionfruit is a bit larger than an average passionfruit.

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The majority of any studies done with the mangosteen fruit to date have been done in a lab. There is minimal work that has been done with people that can indicate the exact benefits someone will receive from taking a daily mangosteen supplement. How ever while it isn’t proven scientifically there are numerous people that praise the benefits of the fruit in prevention therapy for different forms of cancer and other environment illnesses.

The majority of studies focus on the pericarp of the fruit. The dark and woody rind portion, rather then the white tasty fruit inside. The reason that this is the point of focus is simple, that’s where the majority of Xanthones reside. While the fruit itself surely has some healthy benefits, they haven’t been studied to the extent of the rind.

Mangosteen Supplement Information

Those who take a mangosteen supplement generally take it for holistic medical purposes, the best ones being made from the peel, pulp, and hull of the fruit. Ideally a liquid mangosteen supplement is taken once per day in a 30ml to 90ml dose taken through the day rather than all at once.

The better mangosteen supplements don’t contain any sweeteners, preservatives, or stabilizing agents. Reason for this is those chemicals can have a negative effect on the beneficial effects the mangosteen has.

A more popular mangosteen supplement is Mangoxan, it gets it’s name from the mangosteen and the primary antioxidant in the fruit known as Xanthones. The supplement is made from the entire fruit puree, along with some other fruits that are high in antioxidants. The Xanthones are found to be most concentrated in the peel, and hull of the fruit.

Mangoxan is a wonderfully tasty juice, that hold extraordinary benefits as a supplement. The whole mangosteen puree mixed along with the other fruits high in antioxidants offers a vast array of health benefits. This juice is different then anything else available on the market. The xanthones combined with a cocktail of other antioxidants provides amazing health benefits. If you’re searching for a quality mangosteen supplement don’t look any further then Mangoxan.

D Fraser
http://www.articlesbase.com/health-articles/mangosteen-supplement-use-96528.html

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