Pharmaceutical Machinery Manufacturer India

CONTAINMENT TECHNOLOGY BY THE USE OF BARRIER ISOLATORS.

noreply@blogger.com (chamunda pharma) — Sat, 7 Dec 2019 00:28:00 -0800

The Concept of Roll Compactor with Isolators was originally derived by the “Nuclear Industry” in order to keep the operators safe from radioactive Isotopes. Eventually this technology was adopted into the pharmaceutical industry to address operator safety from highly potent API’s. After years of evolution & upgrades the Barrier Isolators are looked upon as safer, easier & cheaper alternatives for handling High Potent API’s (Hormones, Cytotoxic, etc.).

Isolators provide a contained & controlled environment on a smaller scale compared to a clean room. The result is achieving ergonomic operation in an almost germ / contaminants free working atmosphere. All of this is achieved at a much smaller scale with minimized cost of cleaning, air cycles, validation & maintenance in comparison to a clean room.

At Chamunda Containment Solution’s we understand the need of the ever evolving API market to handle API drugs with maximum safety with comparative minimum cost of handling. We are deriving systems which are capable of handling wet, dry mass & Liquid from a range of OEL 3 to OEL 5. We are backed up by consultants from Europe who guides us in achieving the desired goal.

Chamunda has a complete setup for design & manufacturing of both Process equipment’s & Isolators in house. This provides us with absolute control over customization & equipment integration with Rigid Isolators*.

Our Product Range consists of the following.

Sampling & Dispensing Isolator.
Isolator for Granulation.
Isolator for Roll compactor & dry process line.
Isolator for Auto coater.
Close loop Granulation lines.
Colloid mill with containment.

Special Features

Integrated process equipment’s with Rigid –ve pressure Barrier Isolators
Options for material ingress i.e. Pass Box, RTP’s & SBV’s
Options for material discharge i.e. Out Pass Box, RTP’s, SBV’s, and Continuous Liners or BIBO Sleeves.
In Process Containers with SBV’s.
Pressure controlled cycles with Temperature, Humidity & O2 monitoring & control if required.
Integrated WIP systems with Skid.
Drum loading systems.
Safe Change filters.
Glove integrity testing.
Optimum ergonomics via ergo trials.
Complete automation using PLC + HMI (10”- Mitsubishi / optional Siemens make), compliant to 21 CFR if required.
Support for pressure test OEL test provided.
In compliance with cGMP norms.

High Speed Double Rotary Tablet Press Machine

noreply@blogger.com (chamunda pharma) — Thu, 18 Jul 2019 01:51:00 -0700

MACHINE APPLICATION

AMPLUS - III High Speed Double Rotary Tablet Press is aptly designed for use in pharmaceutical Industry for Large Batch size Production for Single Layer as well as Bi-Layer Tablets. It does find its applications in many other similar process industries.

MACHINE OPERATIONAL PRINCIPLE

The material (Blended Powder/ Granules) is to be filled to the die hole through the hopper and the Feeder. Then, the filling volume of the powder is adjusted by motorized Dozer & pressed under the Pre & Main Pressure Rolls. The tablets are formed under this process & discharged automatically through the discharge chute of the Tablet Press.

MACHINE DESCRIPTION

This is a Double Rotary Tablet Press with inbuilt 10 Ton Pre Compression & 10 Ton main Compression, with Key features of Interchangeable Turret facility among 51 STN D / 65 STN B/ 81 STN BB. This ergonomically designed machine is cGMP Compliant Tablet Press meeting all the parameters of Design (smooth corners & surfaces), Operator’s safety, Control systems, Metallurgy, Surface treatment and Easy accessibility for cleaning, assembling and dismantling of components etc.

AMPLUS - III series Rotary Tablet Presses are controlled by 15” IPC WITH COLOUR TOUCH SCREEN WITH 21 CFR PART 11 COMPLIANCE. IPC supports online helps to provide the Automation solutions through internet & hence minimize the Machine Down Time and production loss.

This series of machines are designed and made as per cGMP STANDARD & are capable to meet all international standards including USFDA & MHRA REQUIREMENTS.

A) STRUCTURE

As the name suggests, the robust Structure design provides strength & stability to compression forces without vibration. Its sturdy construction based on 'TIE BEAM' design wherein the top frame, made of special C.I., supports the main body to withstand the pressure load during the entire tableting process. The trembling is also absorbed during the operation based on this structure. The structure is enclosed with SS 304 guards. The Tablet compression zone is covered with thick transparent acrylic guards. The machine is equipped with Anti Vibration mounts at the bottom.

B) TURRET DRIVE

Centrally driven Turret is connected directly on the Main Drive Shaft of Heavy Duty Oil Immersed Gear Box to get the max torque at the Turret. It is designed to meet the standards of Low Noise Level below 80db. Large capacity motor ensures that there are no jerks or slippages while compressing even large tablets of size up to 25mm.

C) TURRET

Highly accurately machined, 3 piece Turret with double tapper roller bearings, has SS 316 Die Table.

Upper & lower Punch Disk is made of Special Grade SGI Casting with Electroless Nickel Plating on the exposed portion in tableting zone. This Electroless Nickel plating provides excellent protection against corrosion from highly abrasive substances, salts, acids, alkali, humidity etc.

In upper Punch Disk, the keyway is given in upper punch bore for shaped punches. The Lower Disk is having the punch brake (Ball Plunger) which holds the lower punch, to reduce the weight variation & the Noise.

The lower wiper seal is fitted on the top part of the punch hole in order to block the Oil & dust from the Punch body.

Dies inserted in Die Holes are locked by specially designed & hardened Die Lock Assemblies.

The interchangeable Turret can be provided with option of ‘51D’, ‘65B’ or ‘81BB’ Tooling.

D) PRE & MAIN COMPRESSION PRESSURE ROLLS ASSEMBLIES

Equal & High pressure of Pre & Main Compression rolls, improves the dwell time for better compression. It eliminates the problem of tablet capping and chipping even for difficult formulations or shaped tablets.

Pre & Main Compression Rolls are specially designed, to deliver uniform Pressure on both the Upper & Lower Punches.

The motorized Lower pressure Roll Assembly has Load Cell, fitted at Center the lower roll, which enables the compressing Force measurement & monitoring. (Numeric as well as Graphical)

E) FILLING CAMS

3 types of the filling Cams are supplied along with the machine. A suitable one should be selected based on the Tablet Thickness. The maximum size of the Filling Cam is 20 mm.

F) FORCE FEEDER MECHANISM

Zero Clearance Force Feeder has User friendly design of the force feeder feeds the granules to the Die cavity uniformly. The Force Feeder has Single stage 3 Paddle design for optimum powder filling. Separate ACVFD Drive for Force Feeder is provided for uniform filling efficiency & weight control as well as to synchronize speed & feed both. Option of Clockwise & Anti Clockwise rotation of paddles can be selected from Touch Screen of IPC. It enables handling of difficult products with characteristics like low B.D., fluffiness, poor flow ability etc.

G) FEATURES & ADVANTAGES OF AUTOMATION

• All machine controls through IPC touch screen.

• Auto sampling based on, either time or revolution or punch nos.

• Initial startup & stop rejection by default

• Auto rejection, of any single tablet, if out of prescribed compaction force limit based on CFC through AWC facility.

• Graphical representation of pressure on individual punches at pre & main compression rolls.

• 4 level password securities to prevent unauthorized use.

• Recipe management & recipe storage.

• Audit trail reports with printing facility.

• Post installation. PLC complaints can be handled by internet through team viewer

H) AWC

• The range of AWC is divided such as control, reject and data store.

• Graphical representation of the value of both pre & main pressure.

• Display of figurer and graph both for the value of pressure on each individual punch.

• Indication / display, of any no. of the selected punch & the respective value of pressure applied on it.

• Filling depth can be adjusted, if the amount of filled powder is exceeded or shortened beyond preset value.

• The faulty tablet will be rejected automatically through Single tablet rejection system.

• All data like production, rejection samples taken. Batch time segments etc. are recorded.

• Discharge chute with three compartments viz. Acceptable tablets, initial / auto reject & sampling tablets gate.

I) CENTRALIZED SCADA MONITORING SYSTEM

Machine input & output status can be observed & monitored, in parallel to the machine connected panel, from outside, by any competent authorized person, while sitting in his office through any internet connected device.

BENEFITS OF SCADA:

• Report generation in PDF.

• Large no of recipe & data storage capability of IPC

• Connectivity to any type of printer.

• Graphical system representation.

• Real time trending

• Alarm history.

• Audit trail.

• Advanced security level.

Tablet Compression Machines Market Size 2019-2026 | Product Capacity, Manufacturers, Share, Value, Consumption, Growth and Segmentation

noreply@blogger.com (chamunda pharma) — Fri, 22 Feb 2019 20:28:00 -0800

The new research from Global QYResearch on TabletCompression Machines Market Report for 2019 expects to offer target gathering of people with the crisp point of view toward market and fill in the learning holes with the assistance of handled data and assessments from industry specialists. The data in the exploration report is all around handled and a report is aggregated by industry experts and prepared specialists in the field to guarantee of the nature of research.

The exploration is sponsored by broad and inside and out auxiliary research which includes reference to different measurable databases, national government archives, applicable patent and administrative databases, news articles, public statements, organization yearly reports, webcasts, budgetary reports, and various interior and outer restrictive databases. This evaluated information is cross-checked with industry specialists from different driving organizations in the market. After the whole confirmation process, these reports are imparted to topic specialists (SMEs) for adding further esteem and to pick up their keen feeling on the exploration. With such powerful procedure of information extraction, check, and finish, we solidly support the nature of our examination. With such broad and inside and out research and far reaching inclusion of data, it is dependably a plausibility of customers finding their ideal data in the report with walled in area of key segments and significant insights in all respects.

The worldwide Tablet Compression Machines advertise is esteemed at xx million US$ in 2018 is relied upon to achieve xx million US$ before the finish of 2025, developing at a CAGR of xx% amid 2019-2025.

This report centers around Tablet Compression Machines volume and incentive at worldwide dimension, territorial dimension and friends level. From a worldwide point of view, this report speaks to generally Tablet Compression Machines advertise measure by investigating authentic information and future prospect. Territorially, this report centers around a few key districts: North America, Europe, China and Japan.

At organization level, this report centers around the creation limit, ex-industrial facility value, income and piece of the pie for every maker canvassed in this report.

CPEB4-FC – Front Control Double Rotary Tablet Press Machine

noreply@blogger.com (Anonymous) — Thu, 13 Sep 2018 03:04:00 -0700

In the entry level segment of Double Rotary Tablet Press, CPEB4-FC is a proven model with the advantage of Front Control Operations.

Features:

User Friendly Compact Design.
Front Controls for Tablet Parameters.
Compression Force up to 10 ton
Main Motor with ACVFD and Electromagnetic Clutch.
Force Feeder with AC Drive**
Bi-Layer Attachment**

Technical Specifications:

MODEL	CPEB4-FC 27 ‘D’	CPEB4-FC 35 ‘B’	CPEB4-FC 45 ‘BB’
No of Stations	27	35	45
Tooling	D	B	BB
Max. Pressure (Ton)	10	6.5**	6.5**
Turret Speed (RPM)	17 to 42	17 to 42	17 to 42
Max Tablet Dia. (mm)	25	16	11
Max Output (Tablets/hr)*	136,080	176,400	226,800
Depth of Fill (mm)	20	17	17
Main Motor	5 HP, 1440 RPM	5 HP, 1440 RPM	5 HP, 1440 RPM
Upper Punch Penetration (mm)	3 to 6	3 to 6	3 to 6
Power Supply	415V, 3Phase, 50Hz	415V, 3Phase, 50Hz	415V, 3Phase, 50Hz

Cantilever Type – Roll Compactor

noreply@blogger.com (Anonymous) — Thu, 13 Sep 2018 02:46:00 -0700

FEATURES

• Cantilever Type Roll Design
• inline cake crusher & 2 stage granulator
• Roll – driven through ACVFD
• Hydraulic power pack for roll pressure & feed screw lifting
• Twin feed screw system for both horizontal & vertical feeding
• De-Aeration system in Vertical Feed Screw
• WIP provision only
• PLC System
• Mechanical Roll loading / unloading arrangement

OPTIONAL FEATURES

• Comprehensive Automation including
• Roll gap measurement & control
• 21 CFR Part 11 compliance
• Vacuum Powder Transfer System
• Closed loop system with structure & surrounding platform

MODEL	CPMRC – 300/125
Working Capacity – Throughput	100 to 400 kg / hr.
Roll Size (mm)	Ø300 X 125 W
Roll Speed	6 To 22 RPM (Variable through ACVFD)
Feed Screw Speed (Horizontal)	10 To 60 RPM (Variable through ACVFD)
Feed Screw Speed (Vertical)	10 To 200 RPM (Variable through ACVFD)
Roll Force	22 Ton by 2 Cylinder
Roll Drive Motor	12.5 HP
Feed Screw Motor (Horizontal)	2.0 HP
Feed Screw Motor (Vertical)	5.0 HP

Élan – Double Rotary High Speed Tablet Making Machine

noreply@blogger.com (Anonymous) — Wed, 7 Sep 2016 21:12:00 -0700

We have left a great impression in the pharmaceutical sectors situated in India as well as other nations for the utmost and impeccable quality of our tablet making machines. The reputation that we have earned is a result of our professional team who considers that the overall quality of the tablet is based on the efficiency and accuracy of the tablet making machines.

Our team concentrates on each aspect during the manufacturing of double rotary high speed tablet making machines

· No compromise in Quality Standard

· Use of High Graded Raw Material

· Following Global Standards

· Focused Examination throughout Manufacturing

· Modern Technology Implementation

· Numerous Post Manufacture Testing

· Ensuring Defined Output

· Ensuring Efficient Output

· Cost Effectiveness

Our main focus is on Élan which is Double Rotary high speed (100 RPM) machine for higher table output with five ton pre - compression and ten ton main compression capable in ONE line ONE MILLION TABLETS PER HOUR. This output is greatest among India's largest manufactures and high end European tablet making machines. This Machine stands out due to its new aesthetic look and ergonomically compact design and is benefitted with higher table output. It combines in one machine the sophistication that today's tableting requirements together with well proven mechanical components and design. This tablet manufacturing machine fabricated from the perfect quality material, which makes this highly reliable and durable. It is fully capable of making different size and shape of tablets. This machine can be used in a 24/7 production environment. The implementation of the advanced technology and sophisticated engineering makes this machinery the perfect in the marketplace. Another major competitive advantage - this machine would be the first in the industry with semi automatic variant.

The Machine is the outcome of the proficiency of our experts who manufacture these with the help of the advanced technology in compliance to the international standards of quality. This Double Rotary High Speed Tablet Making Machines provides excellent throughput apt for various batch manufacturing. This machine is ideally designed by skilled professional along with the experienced engineers and technicians of our company. This machine has exceptional provisions such as Acrylic carbonate upper guards, Electromagnetic Clutch, & Lower Guards etc.

This machine is always chosen owing to their performance, quality in addition to competence. This offers problem free operations, robustly for comprehensive time period with no breaks. It is exceptionally strong as well as. It is unproblematic to maintain and keep clean, very enduring as well as truly faultless for tablet making operations.

This High Speed Double Rotary tableting making machine delivers the imperative aspects that defined a good quality of the tablet including size, profiling, shaping, texture, hardness, and tooling performance, anti-counterfeiting, stability, branding, taste and smell.

Therefore we can always tap all ongoing projects of A & B+ class customers who are eager to have such high outputs but overall, not willing to shell out exorbitant prices. Truly, we intend to do our best shot to capitalize on this monumental opportunity and make this wonderful machine a great success.

Features:

· High Speed tablet making machine with outstanding performance, engineering, and reliability.

· Simple and convenient operation

· Extremely robust quality engineering

· Robust construction

· Perfect dimensions

· Front and easy controls

· Excellent functionality and performance

· Inter locked guards, for safety

· Higher output suitable for large batch production

· Multipunch tablet making

· Electromagnetic Clutch

· Low maintenance

· Easy operation

· Longer service life

· Exceptional durability

· Corrosion resistivity

· Accessibility for ease of cleaning, maintenance and operation

Duo Press – Bilayer Tablet Press

noreply@blogger.com (Anonymous) — Mon, 30 May 2016 01:12:00 -0700

Backed by rich pharmaceutical industry experience, we are ready to offer high speed tablet making machines to our customers. This Chamunda DUO PRESS (Double Rotary Press) stands out due to its new aesthetic look and ergonomically compact design and is benefited with higher table output. It is developed to meet the R & D in the Tableting zone of the medical industry. This wonderful machine comes with the variant tooling like “B”, “D”, “D B” and “D B BB” to meet the specific and customize requirements. This machine is developed following with international standard bearing in mind requirements of customers. Our team focuses on the machinery part during the manufacturing of this machine. This machine is available at market competitive price.

High efficiency manufacture of pharmaceuticals requires the use of great quality tableting presses. Finished tablet is determined by the various operating parameters as well as the performance and design of tablet punches and dies. Bilayer tablet is new concept of tablet for the successful creation of controlled release formulation with numerous features to provide a method of successful medicine delivery system. Bilayer tablet press is useful technology to conquer the shortcoming of the single layered pill. Bilayer pills can be a primary choice to avoid chemical incompatibilities. To reduce capital investment, tablet presses are used to produce such tablets. Using a DUO tablet press may be your perfect approach to producing a quality bi-layer tablets. Especially, when you wants high production output!

This machine is quality updated owing to their functionality, quality, in addition to competence. This provides easy & user-friendly operations, robustly for comprehensive time period with no breaks. It has exceptional supplies such as Electromagnetic Clutch, Adjustable Safety Upper Guard & contacts parts, Adjustable Upper punch penetration, made of SS 316. It is unproblematic to maintain and keep clean, very enduring as well as truly faultless for tablet making operations.

It is reliable and easy to operate with central driven, lubrication for centralized lubrication, and accessible front controls, suitable for large batch production.

Ideal Characteristics of Duo Press:

· Central Drive System

o No torque losses

· Pre Compression Force 5+ tons

o Better deaeration of material

o Perfect Suits for dry granulation

· Compatible for Bilayer Tablets

o Allows Combination of 2 different APIs (Active Pharmaceutical Ingredients)

o For an additional sales preposition

Features at a Glance:

· Drive Arrangement

o Through variable frequency AC Drive, offering a complete solution to your AC Motor Speed.

· All contacts parts made of SS 316

o Contact parts including rotating Feeder Paddles fitted with variable frequency drive, Discharge chute, Hopper, Hopper connector and butterfly valve for flow control

· Three piece turret

o with lower punch wiper seal and SS 316 Die Plate

· Adjustable Safety Upper Guard

o Operational interlock and Fully adjustable

· Dust Nozzle

o with Clamp- used for dust suppression

· Ejection system

o For weight checking or inspection purpose.

· Main motor with ACVFD

o It is reliable and affordable, has flexibility of control, and provides vital electrical energy savings through highly reduced electric bills.

· Adjustable Upper punch penetration

o This feature is very useful when tablet making very Shallow tablets.

· No foundation require because of anti vibration mounting

· Inching System

· High Speed Turret with Electro less nickel plating

· Tablet compression zone

· Anti-Reverse Protection

Optional Features:

· 5.7" Color Touch Screen

· Turret and Feeder Motor Controls

· 3 Level Password Protection

· Drive motor Controls and Fault Indication

· Machine Parameters

· Recipe Management

· Comprehensive Reports

· Force Control Parameters

· Average compaction force indication

Get best pharmaceutical machine to induce top quality granules

noreply@blogger.com (Anonymous) — Wed, 3 Feb 2016 00:58:00 -0800

There are a unit several pharmaceutical corporations on the market nowadays and that they need smart instrumentality which will facilitate to provide high-quality product. The foremost common instrumentality which will facilitate to induce powder granules is Roller compactor. It’s terribly troublesome to cope with dry powder however with the assistance of compactor it's terribly straightforward to relinquish pressure and therefore get granules of various sizes. This kind of pharmaceutical instrumentality is extremely in style because it is extremely straightforward to work and additionally supply optimized material. These forms of granules area unit accustomed build tablets of various size and therefore such straightforward process will facilitate to induce high-quality tablets and can also be used as fillers. Nowadays compactor available is right once needs to induce granules with high-quality process. The potency of labor is additionally augmented with facilitate to such machines. These forms of instrumentality area unit on the market very compact size and therefore will be placed at anywhere. It provides high-quality tablets that area unit fashioned with such powder granules.

Working of roller

The pressure is given to powder from each side to induce grain sin varied size. The complete Roller compactor is dividing into 3 steps which will facilitate to attain a positive result. The primary half is feeding wherever the powder is placed in compaction space. The compaction space is offered between rolls during this kind of pharmaceutical instrumentality. The second half is compaction unit wherever the rolls area unit giving pressure from each side to make powder granules. The force is given to each side that may facilitate to extend pressure in compaction space. The last step is to line size of granules that is offered by compacting powder material. These several vary in step with demand so size reduction unit is offered wherever one will set particle size. Thus, the complete process is extremely straightforward and helps to attain needed result among time. Individuals will go get compactor available and therefore get granules of various sizes that are more used for various functions. The roll compactor machine is offered with the totally atomized system wherever roll pressure, speed and size will be set in step with demand. It’s terribly straightforward to attain density and high-quality grain with the compactor which will be used as filling material in tablets.

What area unit benefits of Roll compactor?

The roll compactor machine is extremely straightforward to work and makers will even scale back staff whereas going for such machine-controlled machine.

The parts on the market in such machine will simply be disassembled that may facilitate to wash components simply. Thus, the pharmaceutical instrumentality will facilitate to relinquish high-quality product simply.

The availability of compactor available will facilitate to induce granules with dirt fee setting. Thus, there's no dirt created whereas coping with dry powder in such kind of machine.

The machines designed considering various factors like safety, setting and top quality.

The roll compactor machine is Associate in Nursing example of contemporary technology here coping with dry powder to induce granules of needed size is extremely straightforward.

The totally automation method build it straightforward to work and therefore facilitate to induce smart results among time. The assembly comes with the various units that enable setting pressure and size simply.

BLITZ Machine: For Better Efficiency and Increased Production

noreply@blogger.com (Anonymous) — Fri, 13 Feb 2015 00:00:00 -0800

Chamunda Pharma Machinery Pvt. Ltd. specializes in the manufacture of BLITZ machine in India. This is a unique rotary press machine which is widely used as a compression machine for tablets. BLITZ machine is used as a tablet press machine in the pharmaceutical sector to manufacture tablets of uniform sizes and weight. The key feature of this machine includes high speed tablet press with front control increasing production with increased output. Its sturdy body makes it easy to operate and is user friendly.

BLITZ Machine stands out from other pharmaceutical machines due to the following salient features.

Salient Features

1.    BLITZ machine has a pre compression force up to 5 ton along with main compression force up to 10 ton.
2.    It has a higher speed operation with a centrally driven Turret drive up to 60 RPM rotating through bearings making its functioning more efficient.
3.    The Force Feeder works up to 120 RPM for compression of fine granules synchronizing speed and feed for the machine.
4.    Its specially designed hydro- pneumatic power pack stabilizes pressure on the machine while loading and over loading release.
5.    It is designed with a three piece turret with a Die Plate of SS316.
6.    The machine has contact parts in SS316.
7.    It has a dust extraction nozzle clamp fitted and is helpful for easy cleaning.
8.    Its acrylic upper guard is firm and sturdy for interlocking and operational safety purpose.
9.    BLITZ machine has all its controls in front for easy operation along with an inbuilt control panel
10.    It has a main motor with ACVFD and Electro Magnetic Clutch along with a force feeder with ACVFD
11.    Its upper punch penetration is easy to operate while designing the granules
12.    The machine has a tunnel type two sided lifting track
13.    BLITZ machine has an arrangement of auto lubrication for centralized lubrication for more efficiency
14.    It has an anti-vibration mount of vibration absorption and is excellent for inching operation
15.    It has a special feature for anti-reverse protection
16.    BLITZ machine has been designed to provide provision for extra plug and socket of single and three phase for de-duster and dust extractor machine connection respectively

We, at Chamunda Pharma have successfully tested BLITZ machine and guarantee it to be the number one for increased production along with increased output. Its unique ergonomic design makes it easy for operational purpose. Its simple structure provides ease in maintaining the machine along with proper cleanliness.

Blitz Machine is specially designed for high speed accuracy along with efficiency for large patch production and more output.Its salient features enable all its parameters to be fine-tuned and make it more user friendly.

Manufacture of the tableting blend

noreply@blogger.com (Anonymous) — Sun, 7 Dec 2014 22:04:00 -0800

In the pill pressing method, the most guideline is to confirm that the acceptable quantity of active ingredient is in every pill. Hence, all the ingredients ought to be well-mixed. If a sufficiently uniform mixture of the elements can't be obtained with straightforward mixing processes, the ingredients should be coarse before compression to assure an excellent distribution of the active compound within the final pill. 2 basic techniques square measure accustomed granulate powders for compression into a tablet press: wet granulation and dry granulation. Powders that may be mixed well don't need granulation and might be compressed into tablets through direct compression.

Wet granulation

Wet granulation could be a method of employing a liquid binder to gently agglomerate the powder mixture. The number of liquid has got to be properly controlled, as over-wetting can cause the granules to be too onerous and under-wetting can cause them to be too soft and friable. binary compound solutions have the advantage of being safer to touch upon than solvent-based systems however might not be appropriate for medicine that square measure degraded by chemical reaction.

Procedure

1.         The active ingredient and excipients square measure weighed and mixed.

2.         The wet granulate is ready by adding the liquid binder–adhesive to the powder mix and admixture completely. Samples of binders/adhesives embody binary compound preparations of starch, natural gums like tree, and polyose derivatives like methyl group polyose, gelatin, and providence.

3.         Screening the damp mass through a mesh to create pellets or granules.

4.         Drying the granulation. a traditional tray-dryer or fluid-bed appliance square measure most typically used.

5.         When the granules square measure dried, they're had a screen of smaller size than the one used for the wet mass to form granules of uniform size.

Low shear wet granulation processes use terribly straightforward admixture instrumentality, and might take a substantial time to attain a uniformly mixed state. High shear wet granulation processes use instrumentality that mixes the powder and liquid at a awfully quick rate, and therefore hurries up the producing method. Fluid bed granulation could be a multiple-step wet granulation method performed within the same vessel to pre-heat, granulate, and dry the powders. It’s used as a result of it permits shut management of the granulation method.

Sieving & Grading Machine GMP Model (Vibro Sifter)

noreply@blogger.com (Anonymous) — Sat, 23 Aug 2014 01:01:00 -0700

Vibro Sifter offered is provided with multi-deck and dust-proof cover support and provides working on vibratory, rotary and magnetic principles that makes these suitable for sieving and screening of chemicals, cosmetics and pharmaceuticals. Finding use in sieving and screening of pharmaceuticals, chemicals, cosmetics, these are offered in different working capacities and are used for separation of mass composition of solid and liquid. These also come with circular gyratory screens that provide for efficient separation of mass composition of liquid from solid, solids from solids.

Features:

•    Simple & Compact construction.
•    Faster Separation
•    Double & Triple deck screens with outlet and hopper for bottom deck
•    available on request.
•    Lesser Maintenance and Power Consumption than the Conventional Sifter.
•    Easy dismantling and cleaning facility

Models	CPMVS 20”	CPMVS 30”
Screen Diameter	510 mm	750 mm
Charging Height	1000 mm	1150 mm
Discharging Height	600 mm	750 mm
Motor	0.5 HP, 3 Ø, A.C.	1 HP, 3 Ø, A.C.

Colloid Mill- State of Art perfect homogenizer | emulsifier | Dispersing | Milling from CHAMUNDA

noreply@blogger.com (Anonymous) — Mon, 4 Aug 2014 21:02:00 -0700

In-depth Knowledge of the domain-Pharma Machinery for Solid Oral Dosage, highly creative professionals and capability to convert imagination in to reality makes CHAMUNDA PHARMA MACHINERY PVT.LTD (CPMPL) as a preferred supplier for Pharma Machinery.

From its inception (1981) with the help of experienced engineers, we are able to offer a wide range of Colloid Mill. The company’s expertise in delivering unmatched products has helped in to earn the reputation of a veteran within the introduction of Colloid Mill during the early stage of companies expansion in early 80’s.

Super fine grind, Homogenize, Disperse, Mix and emulsify in single process TechniK-is one word to define our Colloid Mill.

Principle: A colloid mill does its work by hydraulic shear, bringing to bear a tremendous amount of energy on a small portion of material in the form of a thin film. This will reduce particles to their ultimate crystal size by breaking up the agglomerates into which they form. In the case of emulsions, the same principle holds. As the particles of the dispersed phase of the emulsion get smaller, it requires progressively more energy to overcome the surface tension holding them together. Enormous hydraulic shear is needed to do the job and a colloid mill is the ideal device to apply this force. Please refer attached white paper on Colliod Mill for your kind ref.

CPMPL engineers and application experts are available to assist you with selection of machine type as well as provide you with advice regarding installation of the machine into existing or new process systems. What else do you need? Please write to us in case you need us to attend your specific request if any.

Do your pharmaceutical Tablet Productions require speed and precision.-We have solution for it.

noreply@blogger.com (Anonymous) — Fri, 1 Aug 2014 23:03:00 -0700

Do your pharmaceutical Tablet Productions require speed and precision? CLIT PRESS II-Tablet press Machine is the answer.

Cutting edge technology, great reliability and unique design with easy to use and to maintain, these are the main features of our CLIT PRESS II. It’s really allows to Do your pharmaceutical Tablet Productions require speed and precision.-We have solution for it.-these are the words from the actual user/Machine Operator.

CLIT PRESS II machine is distinguished by the high technology, quality and reliability. These traits are guaranteed by an integrated and continuously upgraded production system. It’s is a modular design able to support various dosing units of powder. The high sophisticated manufacturing technology used for the moving parts ensures the precision of all the machine functions.

The design of CLIT PRESS II means precise functioning and high performances, characteristics which make this Tablet Press machine ideal for production of small, medium and large lots.The many options installed as standard enable CLIT PRESS II to satisfy all the production demands of the pharmaceutical companies.

Clit Press II offers a noticeable modularity:

• The standalone control cabinet contains all electrical and electronic components

• 29 Stations Press is specially designed to compress DS, Capsules & Oval shaped tablets 23mm & 19mmg respectively

• The turret has a wider pitch circle diameter

• Geometry of the compression rolls for extended Dwell time even at a High Speed

• Tablet press equipped with Three Piece Turret with SS 316 Die Plate with Lower Punch Wiper Seal (Wiper seal only in D & B Tooling)

Let’s get to know it better by referring attached details of our CLIT PRESS II- Award Winning Tablet Press Machine.Our Record says this machine is installed at more than 1000 places & this is the highest in number any company has installed for the rated capacity.

Feel free to contact undersigned in case you have any query.

Multi-Purpose Equipment-Redefine the excellence in R&D by Chamunda-India

noreply@blogger.com (Anonymous) — Tue, 29 Jul 2014 21:38:00 -0700

In Innovation, there is no rule except redefining creative excellence by putting your imagination into the reality. Driven by this fact, we at CHAMUNDA have crafted Multi-Purpose R&D equipment to cater the need of R&D Department. These equipment is originally designed a long back but haven’t got an opportunity to present it in a full range. Multi-Purpose Equipment is based on a powerful drive unit available in two versions. The various attachments can be easily and quickly connected by means of a flange coupling.

The Multi-Purpose Equipment is ideal for small scale production in the pharmaceutical, chemical, cosmetic and food industries. It fits perfectly into Research & Development of tablets, ointments, creams and more. The modular design is compact, economical and offers a powerful motor drive with a wide range of easily interchangeable attachments for various purposes.

Main benefits of the modular Multi-Purpose R&D Equipment is:

Little lab space needed
Constant product quality - improved production
Economical capital cost - one drive, many attachments
High quality

For your quick reference we have attached herewith the details of Multi-Purpose R&D Equipment. Hope it’s interesting reading.

With these significant strategic moves today, techno managerial excellence and a blueprint of tomorrow in our mind, we at Chamunda Pharma Machineries believe that tomorrow is truly ours! Isn’t it!

Tablet Press- Double Sided Square Rotary Tablet Press – GMP Model

noreply@blogger.com (Anonymous) — Mon, 28 Jul 2014 23:22:00 -0700

APPLICATION & PROCESS:

Double Sided Tablet Press Machine is used for production of simple and precise tablets from powder in Pharmaceutical and relevant Industries.

KEY FEATURES AT GLANCE

THE MACHINE CONCEPT

The basic construction of the machine consists of:

Rigid base frame fitted on rigid body
Tablet Compression Zone
Electric Control Panel

THE ERGONOMICS DESIGN

The CPEB4 has been completely new designed according to the most modern ergonomic aspects.

• GMP Model

• Easy cleaning and Changeover

• Stainless steel and acrylic surrounding

• Easy to operate and maintenance

THE DRIVE

The machine is equipped with VARIABLE SPEED PULLEY. The turret is driven by PB worm/Equivalent Material fitted to a bearing mounted worm shaft gear box which is driven by motor. Small adjustment between the worm and worm wheel to allow for any wear which can be adjusted in turn extending it’s life.

THE GRAVITY FEED FRAME

Non mechanical open gravity feed frame are standard equipment in this machine. The gravity feed frame fitted with easy removed Fixing knob on rigid base plate and can be easily set and maintained at the desired height. Resetting of the feed frame base is not required during change over and cleaning. The gravity feed frame fitted with re-circulating band to keep avoid spilling of the powder.

THE POWDER LEVEL

Powder level in the feed frame can be easily adjusted by hopper support bracket and knob. These adjustment are possible without having to shut down the machine and open the guard

THE TURRET AND DIE TABLE

We are proposing SS 316 die plate three piece turret along with SS 316 Powder Contact Parts.

THE CAMS DESIGN

For smooth operation, all CAMS are calculated by computer with a harmonic profile to fluent operation and minimum wear.

THE UPPER PUNCH PENETRATION

Adjustable upper punch penetration is provided as a standard features of CPEB4 model. The system provides the following features.

Change of level of compression of the tablet is possible in the die
Reduce ejection loads of difficult product like floppy or sticky
Die life can be increased by changing the level of tablet compression and reversing the dies

THE OVERLOAD AND PRESSURE RELEASE MECHANISM

· The compression spring overload pressure release mechanism fitted to lower pressure roll for applying unique systems fitted to lower pressure roll for applying unique compression force. It combines the advantage of selecting constant force or constant thickness of the tablet press. The overload pressure release ensures any overloading transmitted to the punches without major damage. The overload pressure release should always be set to relieve the pressure with minimum effort consistent with the diameter and hardness of the tablet being made.

THE DUST EXTRACTION ARRANGEMENT

· At high speed, the Dust Extraction system is prerequisite. The effective dust suction nozzles are fitted at compression zone with quick release design for easy cleaning.

THE LUBRICATION SYSTEMS

· The CPEB4 model is equipped with one shot lubrication systems to serve lubrication to all pressure roll pin. Oil cups are provided wherever continuous lubrication is required.

THE NOISE LEVEL

· The compression are is completely encapsulated and the machine itself is surrounded by sound absorbing covering. Therefore, the noise level is below 85 dB even under higher load. The machine is mounted on anti-vibration mounts.

THE CONTROL PANEL

The control panel fitted on front side of the machine. The control panel allows easy and safe adjustment of operating, easy cleaning and gives excess space for setting, change over and cleaning of the machine. The control panel is fitted with digital tablet counter, RPM Meter and Push Buttons. The electric components closed panel installed in the machine cabinet fitted with MCB, Overload relay, Contractors etc.

THE CLEANLINESS AND CLEANABILITY

The tableting zone has no painted surface and corner to avoid dust traps. The large cabinet combined with acrylic guards gives excellent access area for cleaning. Dust extractor nozzle significantly reduces the dust levels in the tableting zone.

THE ELECTRIC AND ELECTRONICS

Clearly defined wiring

High End Products used for longer life & improved Reliability of the machine Enhancing value of product

TECHNICAL SPECIFICATION

Sr.No.	MODEL	CPEB4 – 27 ‘D’ TOOLING	CPEB4 – 35 ‘B’ TOOLING	CPEB4 – 45 ‘BB’ TOOLING
1.	No. Of Station	27	35	45
2.	Tooling	D	B	B
3.	Max. Operating Load (Tons)	10 Tons	6.5 Tons	6.5 Tons
4.	Max. Tablets Dia. (mm)	Ø 25 mm	Ø 16 mm	Ø 11 mm
5.	Max. Depth Of Fill (mm)	20	17.5	17.5
6.	Upper Punch Penetration (mm)	1.5 to 8 mm	1.5 to 8 mm	1.5 to 8 mm

The output will depend on the physical and chemical properties of material being processed. In case of Tableting machine, it depends on tablet shape, weight, thickness & ambient conditions.

Electric voltage and frequency can be provided as per customer’s requirement.

The right for modification in the design and the specs are reserved without prior notice.

Double Rotary Tablet Press machine with Innovative Front Control-Increased Versatility

noreply@blogger.com (Anonymous) — Fri, 25 Jul 2014 22:07:00 -0700

Our motto is to bringing operational excellence to yours by constant upgrading our machines. Major emphasis of our research and development & continuous interaction with the end user has led to many value added products being launched from time to time.

In addition to the numerous expert discussions held for to configure our Double Rotary Tablet Press machine with Innovative Front Control, emphasis has been given for the functionality and features demanded by Production Pharmacist & Tablet Press operator. Moving on this front we came out with our latest version of Double Rotary Tablet Press with Innovative Front Control which is configured to Meet Production Pharmacist Requirements.

Owing to following merits, we are expecting that CPEB4 FC will become a leading name in the domain….

Our CPEB4FC is empowered by Innovative Front Control for to fine-tuned the major tablet parameters during the operation of the machine, thus Increased Productivity & reduced Wastage

Four Easy to use & calibrated knobs to control Table Thickness & Tablet Volume of both the sides

Knobs are provided with Anti-turning Locks to reduce chances of weight variation

The robust construction of the machine ensures smooth running even at a high speed

There is obviously a lot to know about CPEB4 FC, same has been noted in attached documents. Hope it’s interesting reading.

We are very pleased with the level of interest shown by user so far and expects “to sign up a new customer shortly”