tag:blogger.com,1999:blog-42788917804463618092024-09-26T00:10:06.459+01:00This is specifically for updates to the PolygenicPathways site and linked to papers relating to itChris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.comBlogger23125tag:blogger.com,1999:blog-4278891780446361809.post-83441154909526513202016-10-12T06:14:00.001+01:002016-10-12T06:14:22.655+01:00<a href="https://www.blogger.com/HPI.htm"><u><span style="color: blue;">Host pathogen interactomes</span></u></a><u> </u>for <a href="https://www.blogger.com/bornavirus.htm" target="_blank">Bornavirus</a>; <a href="http://www.polygenicpathways.co.uk/borrelia.htm" target="_blank">Borrelia burgdorferri</a>; &nbsp;<a href="https://www.blogger.com/borrelia.htm"><u></u></a><a href="https://www.blogger.com/calbicans.htm"><u><span style="color: blue;">Candida albicans</span></u></a>; <a href="https://www.blogger.com/chlamydia.htm"><u><span style="color: blue;">Chlamydia Pneumoniae</span></u></a> ; <a href="https://www.blogger.com/cryptococcus.htm"><u><span style="color: blue;">Cryptococcus Neoformans</span></u></a>; <a href="https://www.blogger.com/Ebolavirus.htm"><u><span style="color: blue;">Ebola virus</span></u></a>; <a href="https://www.blogger.com/epsteinbarr.htm"><u><span style="color: blue;">Epstein-Barr virus</span></u>;</a> <a href="https://www.blogger.com/helicobacter.htm"><u><span style="color: blue;">Helicobacter pylori</span></u></a>; <a href="https://www.blogger.com/hepatitisc.htm"><u><span style="color: blue;">Hepatitis C virus</span></u></a>;<a href="https://www.blogger.com/herpeshost.html" target="_blank">Herpes simplex (HSV-1)</a>; <a href="https://www.blogger.com/hervw.htm"><span style="color: blue;">HERV-W</span></a>; <a href="http://www.ncbi.nlm.nih.gov/projects/RefSeq/HIVInteractions/" target="_blank"><u><span style="color: blue;">HIV-1,</span> Human Protein Interaction Database</u></a><u> (NCBI);</u> <a href="https://www.blogger.com/cytomegalovirus.htm"><u><span style="color: blue;">Human cytomegalovirus</span></u></a><u>;</u> <a href="https://www.blogger.com/influenza.htm"><u><span style="color: blue;">Influenza A virus</span></u></a><span style="color: blue;">;</span> <a href="https://www.blogger.com/pgingivalis.htm"><u><span style="color: blue;">Porphyromonas Gingivalis</span></u></a>; <a href="https://www.blogger.com/tgondii.htm"><u><span style="color: blue;">Toxoplasma Gondii</span></u></a>; <a href="https://www.blogger.com/Tcruzi.htm"><u><span style="color: blue;">Trypanosoma Cruzi</span></u></a><span style="color: blue;"><u> </u></span>: KEGG pathway analysis of these interactomes can be accessed <a href="http://www.polygenicpathways.co.uk/hpi.htm" target="_blank">here&nbsp;</a>&nbsp;Dengue virus interactome from <a href="http://proline.biochem.iisc.ernet.in/DenHunt/" target="_blank">DenHunt</a>&nbsp;<a href="http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0004965" target="_blank">(Karyala et al, 2016</a>)Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-18688279947275272282015-12-06T19:05:00.001+00:002015-12-06T19:05:28.582+00:00<a href="http://www.polygenicpathways.co.uk/Bornakegg.htm" target="_blank">KEGG pathway analysis</a> of the host arm of the Bornavirus interactomeChris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-21004665372202800422015-04-18T12:54:00.001+01:002015-04-18T12:54:20.920+01:00<a href="http://www.polygenicpathways.co.uk/borrelia.htm">Interactome</a><br /> <br /> <a href="http://www.polygenicpathways.co.uk/borreliaKegg.htm" target="_blank">Kegg pathway interactome analysis&nbsp; </a>Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-90408642524374507642013-07-25T17:18:00.000+01:002013-07-25T17:18:11.850+01:00<div dir="ltr" style="text-align: left;" trbidi="on"> also with <a href="http://www.polygenicpathways.co.uk//HERPESKEGG.htm" target="_blank">KEGG pathway analysis</a> of the interactome</div> Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-81027318712679842802012-09-19T09:06:00.001+01:002012-09-19T09:06:07.250+01:00Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-58527183593639602452012-09-10T22:01:00.001+01:002012-09-10T22:01:55.762+01:00Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-46963914326602686152012-06-20T07:07:00.001+01:002012-06-20T07:07:57.122+01:00<a href="http://www.polygenicpathways.co.uk/pwaysportal.htm" target="_blank">KEGG pathways</a> have been updated for all diseases - including many pathogen entry pathways relevant to the viruses, bacteria and parasites implicated in each..Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-64595378387123043192012-05-21T10:56:00.001+01:002012-05-22T09:37:52.195+01:00<h2 style="font-weight: normal;"> <a href="http://www.polygenicpathways.co.uk/cfatpathways.htm" target="_blank">Chronic Fatigue pathways</a></h2>Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-33739978293352661012012-04-29T00:19:00.001+01:002012-04-29T00:25:11.596+01:00KEGG have added a number of pathways to their database: <a href="http://www.polygenicpathways.co.uk/keggszgenes.htm">This page relates to the many etched out by schizophrenia susceptibility genes. </a>Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-52134634841891371272011-12-26T13:37:00.000+00:002011-12-27T06:36:45.747+00:00<a href="http://www.polygenicpathways.co.uk/Kegg/depressionkegg.htm">The Pathways are here</a>Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-25594527899813355002011-11-13T22:42:00.000+00:002011-11-13T22:42:11.821+00:00<a href="http://www.polygenicpathways.co.uk/Kegg/adhdpathway.htm">KEGG pathway analysis of ADHD genes</a><br /> <br /> <a href="http://www.mendeley.com/import/?url=[CURRENT-PAGE-URL]" title="Add this article to your Mendeley library"></a>Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-60792309607238618992011-11-11T21:14:00.001+00:002011-11-11T21:14:35.108+00:00<a href="http://www.polygenicpathways.co.uk/Kegg/obesitypathways.htm">KEGG pathways of childhood obesity genes</a>Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-408649740180180982011-11-03T19:57:00.000+00:002011-11-06T17:04:45.034+00:00Follow this link: <a href="http://www.polygenicpathways.co.uk/Kegg/anorexiapathways.htm">KEGG pathway analysis of Anorexia Genes</a>Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-20579152435976350772011-09-02T19:21:00.000+01:002011-09-02T19:22:47.698+01:00In press: <a href="http://www.hindawi.com/journals/ijad/aip/501862/">International Journal of Alzheimer's disease:</a><br /> Alzheimer’s disease: APP, <a class="zem_slink" href="http://en.wikipedia.org/wiki/Gamma_secretase" rel="wikipedia" target="_blank" title="Gamma secretase">gamma secretase</a>, APOE, CLU, <a class="zem_slink" href="http://en.wikipedia.org/wiki/Complement_receptor_1" rel="wikipedia" target="_blank" title="Complement receptor 1">CR1</a>, <a class="zem_slink" href="http://en.wikipedia.org/wiki/PICALM" rel="wikipedia" target="_blank" title="PICALM">PICALM</a>, ABCA7, <a class="zem_slink" href="http://en.wikipedia.org/wiki/BIN1" rel="wikipedia" target="_blank" title="BIN1">BIN1</a>, <a class="zem_slink" href="http://en.wikipedia.org/wiki/CD2AP" rel="wikipedia" target="_blank" title="CD2AP">CD2AP</a>, <a class="zem_slink" href="http://en.wikipedia.org/wiki/CD33" rel="wikipedia" target="_blank" title="CD33">CD33</a>, <a class="zem_slink" href="http://en.wikipedia.org/wiki/EPH_receptor_A1" rel="wikipedia" target="_blank" title="EPH receptor A1">EPHA1</a> and MS4A2, and their relationships with <a class="zem_slink" href="http://en.wikipedia.org/wiki/Herpes_simplex" rel="wikipedia" target="_blank" title="Herpes simplex">herpes simplex</a> , C.Pneumoniae, other suspect pathogens and the <a class="zem_slink" href="http://en.wikipedia.org/wiki/Immune_system" rel="wikipedia" target="_blank" title="Immune system">immune system</a>: <br /> <a class="twitter-share-button" count="none" href="http://twitter.com/share" via="ChristophCarter">Tweet</a><script src="http://platform.twitter.com/widgets.js" type="text/javascript"> </script> <br /> <a href="http://www.hypersmash.com/dreamhost/" id="iZ164"> </a><br /> <div class="zemanta-pixie" style="height: 15px; margin-top: 10px;"> <a class="zemanta-pixie-a" href="http://www.zemanta.com/" title="Enhanced by Zemanta"><img alt="Enhanced by Zemanta" class="zemanta-pixie-img" src="http://img.zemanta.com/zemified_e.png?x-id=4019da9f-4654-4984-af87-b9f03c6d2ce2" style="border: medium none; float: right;" /></a></div> Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-89363053382603891502011-08-24T06:17:00.000+01:002011-08-24T06:17:24.496+01:00<span class="zemanta-img separator" style="clear: right;"><a href="http://commons.wikipedia.org/wiki/File:People_living_with_HIV_AIDS_world_map.PNG" style="clear: right; display: block; float: right; margin-left: 1em; margin-right: 1em;"><img alt="Estimated number of people in the world living..." height="139" src="http://upload.wikimedia.org/wikipedia/commons/thumb/6/68/People_living_with_HIV_AIDS_world_map.PNG/300px-People_living_with_HIV_AIDS_world_map.PNG" style="border: none; font-size: 0.8em;" width="300" /></a><span class="zemanta-img-attribution" style="clear: both; float: right; margin-left: 1em; margin-right: 1em; width: 300px;">Image via <a href="http://commons.wikipedia.org/wiki/File:People_living_with_HIV_AIDS_world_map.PNG">Wikipedia</a></span></span>Deleterious and beneficial viruses and other pathogens affecting HIV-1 infection and <a class="zem_slink" href="http://en.wikipedia.org/wiki/Autoantibody" rel="wikipedia" title="Autoantibody">autoantibodies</a> observed in <a class="zem_slink" href="http://en.wikipedia.org/wiki/AIDS" rel="wikipedia" title="AIDS">AIDS</a> are listed <a href="http://www.polygenicpathways.co.uk/aidshiv.htm">here </a><br /> <br /> <br /> <br /> <a class="twitter-share-button" count="none" href="http://twitter.com/share" via="ChristophCarter">Tweet</a><script src="http://platform.twitter.com/widgets.js" type="text/javascript"> </script> <br /> <a href="http://www.hypersmash.com/dreamhost/" id="iZ164"><br /> </a><br /> <div class="zemanta-related"><h6 class="zemanta-related-title" style="font-size: 1em; margin: 1em 0pt 0pt;">Related articles</h6><ul class="zemanta-article-ul"><li class="zemanta-article-ul-li"><a href="http://www.webmd.com/hiv-aids/news/20110817/study-may-aid-search-for-aids-vaccine?src=RSS_PUBLIC">New Study May Aid Search for AIDS Vaccine</a> (webmd.com)</li> </ul></div><div class="zemanta-pixie" style="height: 15px; margin-top: 10px;"><a class="zemanta-pixie-a" href="http://www.zemanta.com/" title="Enhanced by Zemanta"><img alt="Enhanced by Zemanta" class="zemanta-pixie-img" src="http://img.zemanta.com/zemified_e.png?x-id=ca8e9cf5-1d10-4504-9508-7147a5a6c6c8" style="border: medium none; float: right;" /></a></div>Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-90705772529563353352011-08-08T09:50:00.000+01:002011-08-08T09:50:44.304+01:00<a href="http://www.polygenicpathways.co.uk/alzenvrisk.htm">Alzheimer's risk factors</a><br /><br />Including numerous autoantibodies and a role for treponemesChris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-48381947759835270332011-07-19T07:18:00.001+01:002011-07-22T07:30:25.813+01:00The pathways have been updated with recent inputs fom the <a href="http://www.polygenicpathways.co.uk/herpeshost.html">host/pathogen interaction page</a> and with a number of new pathways that&nbsp; KEGG have added to their database.<br /> <a href="http://www.polygenicpathways.co.uk/keggcftrintact.htm" target="_blank"></a>Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-66518365597812578902011-07-18T16:14:00.001+01:002011-07-22T16:45:48.305+01:00The genetic pathways have been updated with new genes and with new pathways from KEGG. Those interacting with herpes simplex are also colour coded. <br /> <a href="http://www.polygenicpathways.co.uk/keggcftrintact.htm" target="_blank"></a>Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-81920626126203639092011-07-15T20:03:00.001+01:002011-07-24T20:07:18.149+01:00<a href="http://www.polygenicpathways.co.uk/AIDShiv.htm">See AIDS/HIV page </a><br /> <br /> <br /> <div class="zemanta-pixie" style="height: 15px; margin-top: 10px;"> <a class="zemanta-pixie-a" href="http://www.zemanta.com/" title="Enhanced by Zemanta"><img alt="Enhanced by Zemanta" class="zemanta-pixie-img" src="http://img.zemanta.com/zemified_e.png?x-id=822bcd08-643f-4c4b-847a-f4f266a87ad8" style="border: medium none; float: right;" /></a></div> Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-31548580147926435322011-06-27T09:02:00.000+01:002011-07-22T09:04:24.319+01:00This dataset desribes the genes that modify HIV-1 infection, as well as the autoantigens reported in HIV-1/AIDS: A list of antiviral strategies is also provided.Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-41473448125741805392011-04-15T07:30:00.001+01:002011-08-07T09:27:25.707+01:00Cystic fibrosis <a href="http://www.polygenicpathways.co.uk/keggcftrintact.htm" target="_blank">CFTR interactome </a>Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-32792986499080805362011-02-21T07:27:00.000+00:002011-07-22T07:29:07.053+01:00This dataset reports host/pathogen interaction for helicobacter pylori, a pathogen implicated in gastric ulcers and cancer, but also in a number of other diseasesChris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0tag:blogger.com,1999:blog-4278891780446361809.post-14392056922342091592011-02-01T18:35:00.000+00:002011-07-22T18:39:31.836+01:00This is a KEGG pathway analysis of the The <a href="http://www.ncbi.nlm.nih.gov/RefSeq/HIVInteractions/">HIV-1, human protein interaction database</a> from NCBI&nbsp; <br /> <a href="http://www.polygenicpathways.co.uk/keggcftrintact.htm" target="_blank"></a>Chris Carterhttp://www.blogger.com/profile/12674373470269272525noreply@blogger.com0