https://www.pnas.org/loi/pnas?af=R Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents Proceedings of the National Academy of Sciences en-US Proceedings of the National Academy of Sciences https://www.pnas.org/cms/asset/433b8ee2-291a-4032-a821-9a689e8fcaa8/default_cover.png https://www.pnas.org/loi/pnas?af=R https://www.pnas.org/doi/abs/10.1073/iti2226123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/> In This Issue doi:10.1073/iti2226123 Proceedings of the National Academy of Sciences 2026-06-02T07:00:00Z Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/iti2226123 https://www.pnas.org/doi/abs/10.1073/iti2226123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2522064123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>Polyploidy, also known as whole genome duplication, is a major evolutionary force in plants, driving diversification and the generation of novel phenotypic variation, including superior abiotic and biotic stress tolerance. The enhanced stress resilience ... Genome evolution through polyploidy: Enhancing plant stress resilience in agriculture doi:10.1073/pnas.2522064123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Patrick P. EdgerMelanie J. A. BodySonia De DonnoAdrian E. PlattsJianrong WangJiming JiangaDepartment of Horticulture, Michigan State University, East Lansing, MI 48824bGenetics and Genome Sciences, Michigan State University, East Lansing, MI 48824cHonors College, Michigan State University, East Lansing, MI 48824dDepartment of Computational Mathematics, Science, and Engineering, Michigan State University, East Lansing, MI 48824eDepartment of Plant Biology, Michigan State University, East Lansing, MI 48824 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2522064123 https://www.pnas.org/doi/abs/10.1073/pnas.2522064123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2522063123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>In native environments, organisms are faced with an array of acute or chronic stresses. These stresses include toxins, pathogens, and physical injury. An increasingly recognized response to diverse stresses is whole genome doubling or polyploidy. This ... Growth under pressure: The pros and cons of polyploidy induced by stress doi:10.1073/pnas.2522063123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Lilijana Sarabia OliverPaulo B. BelatoJoshua SilvaAnna SelmeckiDonald T. FoxAdrienne H. K. Roederahttps://ror.org/05bnh6r87Polyploidy Integration and Innovation Institute, Cornell University, Ithaca, NY 14853bSection of Plant Biology, School of Integrative Plant Science, and Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca NY 14853chttps://ror.org/00py81415Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710dhttps://ror.org/017zqws13Department of Microbiology and Immunology, University of Minnesota School of Medicine, Minneapolis, MN 55455 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2522063123 https://www.pnas.org/doi/abs/10.1073/pnas.2522063123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2522073123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>Escalating pressures of global climate change necessitate developing agricultural systems and crop varieties with enhanced resilience. Polyploidy, the state of possessing multiple complete sets of chromosomes arising from whole genome duplication (WGD), ... Harnessing polyploidy for climate-resilient crops: Lessons from the evolutionary model, allotetraploid cotton doi:10.1073/pnas.2522073123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Maojun WangRuipeng WangGuanjing HuXianlong ZhangJonathan F. Wendelahttps://ror.org/023b72294National Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan 430070, Chinabhttps://ror.org/04rswrd78Department of Ecology, Evolution, and Organismal Biology, Iowa State University, Ames, IA 50011chttps://ror.org/0313jb750National Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Institute of Cotton Research, Chinese Academy of Agricultural Sciences, Anyang 455000, Chinadhttps://ror.org/0313jb750Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Genome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518120, China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2522073123 https://www.pnas.org/doi/abs/10.1073/pnas.2522073123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2604018123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>The Royal Swedish Academy of Sciences awarded the 2025 Nobel Prize in Physics jointly to John Clarke, Michel H. Devoret, and John M. Martinis for their foundational discovery of macroscopic quantum mechanical tunneling and energy quantization in ... Profile of John Clarke, Michel H. Devoret, and John M. Martinis: 2025 Nobel laureates in Physics doi:10.1073/pnas.2604018123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Andrew N. ClelandSteven M. GirvinaPritzker School of Molecular Engineering, University of Chicago, Chicago IL 60637bDepartment of Physics, Yale University, New Haven CT 06520 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2604018123 https://www.pnas.org/doi/abs/10.1073/pnas.2604018123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2533976123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/> Ecology is not yet ready for AI—and why that matters doi:10.1073/pnas.2533976123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Gayatri Mishraahttps://ror.org/05dk0ce17Institute of Biological Chemistry, The Washington State University, Pullman, WA 99164 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2533976123 https://www.pnas.org/doi/abs/10.1073/pnas.2533976123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2537064123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificancePhotovoltaic subretinal prosthesis can restore form vision in patients blinded by age-related macular degeneration. However, residual photoreceptors surrounding the degenerate area can substantially alter the responses of the inner retinal ... Residual photoreceptors affect the response of a degenerate retina to electrical stimulation doi:10.1073/pnas.2537064123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Keith LyMohajeet B. BhuckoryDavis Pham-HowardAnna Kochnev GoldsteinNathan JensenDaniel PalankeraHansen Experimental Physics Laboratory, Stanford University, Stanford, CA 94303bDepartment of Ophthalmology, Stanford University, Stanford, CA 94303cDepartment of Electrical Engineering, Stanford University, Stanford, CA 94303 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2537064123 https://www.pnas.org/doi/abs/10.1073/pnas.2537064123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2537678123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceSmall water bodies (SWBs) are critical but often overlooked components of the global carbon cycle. We demonstrate that human activities, particularly agricultural nutrient loading and urbanization, amplify climate-driven greenhouse gas ... Human amplification of climate-induced greenhouse gas emissions from global small water bodies doi:10.1073/pnas.2537678123 Proceedings of the National Academy of Sciences 2026-05-18T07:00:00Z Xuliang ZhuangXiaoxuan LiuShengjun XuXu WangAamer Ali ShahLei WangShanghua WuCancan JiangZhiyun OuyangShilong PiaoaResearch Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, Chinabhttps://ror.org/05qbk4x57College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, Chinachttps://ror.org/04c4dkn09School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230027, Chinadhttps://ror.org/04s9hft57Department of Microbiology, Faculty of Biological Sciences Quaid-i-Azam University, Islamabad 45320, Pakistanehttps://ror.org/02v51f717Institute of Carbon Neutrality, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2537678123 https://www.pnas.org/doi/abs/10.1073/pnas.2537678123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2532741123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceIsotopic studies of human remains can track changes in dietary variation across transitions from wild food procurement to food production. In Kenya and Tanzania, foragers and fishers of the African Humid Period had highly varied approaches to ... Isotopic evidence for dietary variability among eastern Africa’s first pastoralists doi:10.1073/pnas.2532741123 Proceedings of the National Academy of Sciences 2026-05-18T07:00:00Z Kendra L. ChritzElizabeth A. SawchukMary E. PrendergastScott A. BlumenthalThure E. CerlingJulie DunneSteven T. GoldsteinKatherine M. GrilloAnneke JanzenPurity KiuraJulia Lee-ThorpMarta Mirazón LahrFredrick K. ManthiEmmanuel K. NdiemaFredrick OdedeThomas W. PlummerJensen WainwrightElisabeth A. Hildebrandahttps://ror.org/03rmrcq20Department of Earth, Ocean and Atmospheric Sciences, University of British Columbia, Vancouver V6T 1Z4, Canadabhttps://ror.org/04b8x5a95Department of Anthropology, Cleveland Museum of Natural History, Cleveland, OH 44106chttps://ror.org/008zs3103Department of Anthropology, Rice University, Houston, TX 77005dhttps://ror.org/0293rh119Department of Anthropology, University of Oregon, Eugene, OR 97401ehttps://ror.org/03r0ha626Department of Geology and Geophysics, University of Utah, Salt Lake City, UT 84112fhttps://ror.org/0524sp257School of Chemistry, University of Bristol, Bristol BS8 1QU, United Kingdomghttps://ror.org/01an3r305Department of Anthropology, University of Pittsburgh, Pittsburgh, PA 15260hhttps://ror.org/02y3ad647Department of Anthropology, University of Florida, Gainesville, FL 32611ihttps://ror.org/020f3ap87Department of Anthropology, University of Tennessee Knoxville, Knoxville TN 37996jhttps://ror.org/04sjpp691National Museums of Kenya, Nairobi 00100, Kenyakhttps://ror.org/052gg0110School of Archaeology, Oxford University, Oxford OX1 3TG, United Kingdomlhttps://ror.org/013meh722Department of Archaeology, Cambridge University, Cambridge CB2 3DZ, United Kingdommhttps://ror.org/023pskh72Department of History and Archaeology, Maseno University, Maseno 40105, Kenyanhttps://ror.org/02nf34254Department of Anthropology, Queens College, Flushing, NY 11367ohttps://ror.org/05qghxh33Department of Anthropology, Stony Brook University, Stony Brook, NY 11794 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2532741123 https://www.pnas.org/doi/abs/10.1073/pnas.2532741123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2601794123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificancePolar regions are often treated as evolutionary backwaters, yet they can connect continents and impose extreme selection. From the Late Cretaceous (73 Ma) Prince Creek Formation of Alaska (~80–85°N), we describe three species of ... Arctic ecosystems shaped mammalian dispersal and diversification before the Cretaceous–Paleogene mass extinction doi:10.1073/pnas.2601794123 Proceedings of the National Academy of Sciences 2026-05-18T07:00:00Z Sarah L. ShelleyJaelyn J. EberleGregory M. EricksonPatrick S. DruckenmilleraSchool of Natural Sciences, University of Lincoln, Brayford Pool, Lincoln LN6 7TS, United KingdombUniversity of Colorado Museum of Natural History, University of Colorado, Boulder, CO 80309cDepartment of Earth Science, University of Colorado, Boulder, CO 80309dDepartment of Biological Science, Florida State University, Tallahassee, FL 32306eUniversity of Alaska Museum, University of Alaska Fairbanks, Fairbanks, AK 99775fDepartment of Geosciences, University of Alaska Fairbanks, Fairbanks, AK 99775 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2601794123 https://www.pnas.org/doi/abs/10.1073/pnas.2601794123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2535700123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceHybrids between sexually reproducing animal species are sometimes characterized by unorthodox reproduction such as parthenogenesis or hybridogenesis (clonal transmission of half of the genome and elimination of the other). Understanding how ... Hybridogenesis as an intermediate step between sexual reproduction and parthenogenesis in stick insects doi:10.1073/pnas.2535700123 Proceedings of the National Academy of Sciences 2026-05-22T07:00:00Z Alexander BrandtGuillaume LavanchyVincent MérelLuca SoldiniMorgane MassyZoé DumasEmelyne GaudichauMarjorie LabédanFalon Pasquier GenoudMarc BastardotTanja Schwanderahttps://ror.org/019whta54Department of Ecology and Evolution, University of Lausanne, Lausanne CH-1015, Switzerlandbhttps://ror.org/03zdwsf69Institute for Biosciences, University of Rostock, Rostock 18059, Germanychttps://ror.org/012a77v79Biodiversity and Evolution Unit, Department of Biology, Lund University, Lund 223 62, Sweden Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2535700123 https://www.pnas.org/doi/abs/10.1073/pnas.2535700123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2522069123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificancePolyploid titan cells are central toCryptococcus neoformanspersistence during infection, yet how they reduce ploidy to generate daughter cells was unclear. In most eukaryotes, the meiosis-related proteins Spo11 and Dmc1 are best known for ... Meiosis-specific genes play roles in ploidy reduction in Cryptococcus neoformans titan cells doi:10.1073/pnas.2522069123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Zhuyun BianKayla WilhoitJulian LiberAnushka PeerZiyan XuPaul M. MagweneSheng SunJoseph HeitmanaDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710bDepartment of Biology, Duke University, Durham, NC 27708 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2522069123 https://www.pnas.org/doi/abs/10.1073/pnas.2522069123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2522065123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>Polyploidization, the consequence of genome doubling, is a macromutation that reshapes genomes, phenotypes, and ecological interactions. Polyploidization often results in novel phenotypes, including alterations in size, physiology, biochemistry, and ... Polyploidy: A macromutational force pushing bioeconomic developments doi:10.1073/pnas.2522065123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Marlies K. R. PeetersYves Van de Peerahttps://ror.org/00cv9y106Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, BelgiumbFlanders Research Institute for Agriculture, Fisheries and Food, Plant Sciences Unit, Melle 9090, BelgiumcVIB Center for Plant Systems Biology, Ghent 9052, Belgiumdhttps://ror.org/00g0p6g84Centre for Microbial Ecology and Genomics, Department of Biochemistry, Genetics and Microbiology, University of Pretoria, Pretoria 0028, South Africaehttps://ror.org/05td3s095College of Horticulture, Academy for Advanced Interdisciplinary Studies, Nanjing Agricultural University, Nanjing 210095, China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2522065123 https://www.pnas.org/doi/abs/10.1073/pnas.2522065123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2421731122?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceLand conservation initiatives, including protected areas, community-based management, and payments for ecosystem services, are crucial to sustainable human-environment systems. We propose eight design principles for conservation that can ... Emerging design principles for environmental, economic, and equity successes in land conservation doi:10.1073/pnas.2421731122 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Katharine R. E. SimsJennifer M. Alix-Garciaahttps://ror.org/028vqfs63Economics and Environmental Studies, Amherst College, Amherst, MA 01002bhttps://ror.org/00ysfqy60Applied Economics, Oregon State University, Corvallis, OR 97331 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2421731122 https://www.pnas.org/doi/abs/10.1073/pnas.2421731122?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2534913123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceSoils underpin food production, regulate the climate, and sustain terrestrial ecosystems, yet their condition is shifting rapidly under the combined pressures of human activity and climate change. Understanding how soils respond across decades,... A large-scale framework for estimating soil carbon, nitrogen, pH, and salinity dynamics for 1985–2023 doi:10.1073/pnas.2534913123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Matteo Dalle VaglieSaverio FranciniGherardo ChiriciFederico MartellozzoaDepartment of Economics and Management, University of Florence, Florence 50127, ItalybDepartment of Agricultural and Food Sciences, University of Bologna, Bologna 40127, ItalycDepartment of Agricultural, Food, Environment and Forestry Science and Technology, University of Florence, Florence 50144, Italy Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2534913123 https://www.pnas.org/doi/abs/10.1073/pnas.2534913123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2534056123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceHow Earth acquired its oxygen-rich atmosphere remains a pivotal question in Earth science. By analyzing secular changes in the thermal state of subduction zones inferred from metamorphic thermobaric ratios (T/P), we evaluate whether the ... Subduction modulated the long-term oxygenation of Earth’s surface doi:10.1073/pnas.2534056123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Wei ShiChao LiBenjamin J. W. MillsMichael BrownTim E. JohnsonThomas J. AlgeoMingcai HouChunlian WangMingyu ZhaoSimon W. PoultonaState Key Laboratory of Oil and Gas Reservoir Geology and Exploitation & Institute of Sedimentary Geology, Chengdu University of Technology, Chengdu 610059, ChinabKey Laboratory of Deep-time Geography and Environment Reconstruction and Applications of Ministry of Natural Resources, Chengdu University of Technology, Chengdu 610059, ChinacInternational Center for Sedimentary Geochemistry and Biogeochemistry Research, Chengdu University of Technology, Chengdu 610059, ChinadSchool of Earth, Environment and Sustainability, University of Leeds, Leeds LS2 9JT, United KingdomeLaboratory for Crustal Petrology, Department of Geological, Environmental, and Planetary Sciences, University of Maryland, College Park, MD 20742-4211fCurtin Frontier Institute for Geoscience Solutions, School of Earth and Planetary Sciences, Curtin University, Perth, WA 6845, AustraliagState Key Laboratory of Geomicrobiology and Environmental Changes, China University of Geosciences, Wuhan 430074, ChinahDepartment of Geosciences, University of Cincinnati, Cincinnati, OH 45221iMinistry of Natural Resources Key Laboratory of Metallogeny and Mineral Assessment, Institute of Mineral Resources, Chinese Academy of Geological Sciences, Beijing 100037, ChinajState Key Laboratory of Lithospheric and Environmental Coevolution, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100029, China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2534056123 https://www.pnas.org/doi/abs/10.1073/pnas.2534056123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2524894123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceMaintaining balance becomes increasingly challenging with aging, partly due to sensory system degradation. In parallel, cortical involvement in balance maintenance is hypothesized to increase. However, this hypothesis rests on indirect ... Aging increases the cortical resources allocated to static balance maintenance doi:10.1073/pnas.2524894123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Thomas LegrandScott J. MongoldLaure MüllerMaxime NiesenZoritsa DemerdzievPierre CoemelckEsranur Yildiran CarlakAntonella IannottaGilles NaeijeMathieu BourguignonMarc Vander Ghinstahttps://ror.org/01r9htc13Laboratory of Functional Anatomy, Faculty of Human Motor Sciences, Université Libre de Bruxelles, Brussels, Belgiumbhttps://ror.org/05m7pjf47School of Electrical and Electronic Engineering, University College Dublin, Dublin, Irelandchttps://ror.org/01r9htc13Service d’ORL et de Chirurgie Cervico-Faciale, Hôpital Universitaire de Bruxelles - Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgiumdhttps://ror.org/01r9htc13Laboratoire de Neuroanatomie et Neuroimagerie Translationnelles, Neuroscience Institute, Université libre de Bruxelles, Brussels, Belgiumehttps://ror.org/01r9htc13Centre de Référence Neuromusculaire, Department of Neurology, Hôpital Universitaire de Bruxelles - Hôpital Erasme, Université libre de Bruxelles, Brussels, BelgiumfWalloon ExceLlence Research Institute, Wavre 1300, Belgique Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2524894123 https://www.pnas.org/doi/abs/10.1073/pnas.2524894123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2532984123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceThere is a growing global demand for gold (Au), spurring the exploration of the sustainable technology to recover it from industrial waste. Herein, we present a simple and ecofriendly approach that transforms ordinary rice paper (RP), a starch-... Rice paper adsorbent for gold recovery doi:10.1073/pnas.2532984123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Seung Su ShinSeungho LeeSung-Joon ParkSungkwon JeonJiyun ChungWonhee JoChan Hee JungWangyun WonJung-Hyun LeeaDepartment of Chemical and Biological Engineering, Korea University, Seoul 02841, Republic of KoreabDepartment of Polymer Science and Engineering, Kyungpook National University, Daegu 41566, Republic of KoreacDepartment of Polymer Science and Engineering, Kumoh National Institute of Technology, Gumi, Gyeongbuk 39177, Republic of Korea Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2532984123 https://www.pnas.org/doi/abs/10.1073/pnas.2532984123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2525381123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceThe public and governments around the world are interested in effective policies to improve economic opportunities, particularly for children born to disadvantaged families. From a demographic perspective, we present a set of empirical ... China’s one-child policy amplifies intergenerational inequality via enlarged differential fertility doi:10.1073/pnas.2525381123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Yewen YuYi FanJunjian Yiahttps://ror.org/033vjfk17Institute for Advanced Study, Wuhan University, Wuhan 430072, Chinabhttps://ror.org/013e0zm98Department of Economics, School of Economics, Beijing Technology and Business University, Beijing 100084, Chinachttps://ror.org/01tgyzw49Department of Real Estate, Business School, National University of Singapore, Singapore 119245, Singaporedhttps://ror.org/02v51f717China Center of Economic Research, Peking University, Beijing 100871, Chinaehttps://ror.org/02v51f717National School of Development, Peking University, Beijing 100871, Chinafhttps://ror.org/02v51f717Institute for Global Health and Development, Peking University, Beijing 100871, China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2525381123 https://www.pnas.org/doi/abs/10.1073/pnas.2525381123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2531932123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceProteins undergo two fundamental types of phase transitions—amyloid aggregation and liquid–liquid phase separation (LLPS)—that shape cellular organization and contribute to diseases ranging from Alzheimer’s to cancer. While these processes are ... amyloid-predict and LLPS-predict: Predicting phase separation propensities in the intrinsically disordered proteome doi:10.1073/pnas.2531932123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Samuel LoboLeif GriemM. Scott ShellJoan-Emma Sheaahttps://ror.org/02t274463Department of Chemical Engineering, University of California, Santa Barbara, CA 93106bhttps://ror.org/02t274463Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106chttps://ror.org/02t274463Department of Physics, University of California, Santa Barbara, CA 93106 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2531932123 https://www.pnas.org/doi/abs/10.1073/pnas.2531932123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2537944123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificancePolitical and organizational leaders rely on advisors to make decisions. Ideally, leaders select honest advisors and not sycophants who praise and support the leader to gain personal or professional advantage. We show that avoiding sycophancy ... Rational sycophants and catastrophic risks doi:10.1073/pnas.2537944123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Robert AxelrodScott E. PageaFord School of Public Policy, University of Michigan, Ann Arbor, MI 48104bRoss School of Business, Santa Fe Institute, Santa Fe, NM 87501 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2537944123 https://www.pnas.org/doi/abs/10.1073/pnas.2537944123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2601239123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceThis Perspective proposes an operational neurobiological account of thought and identifies a specific transformation by which some thoughts become conscious. Drawing on the neuroscience of decision-making, it argues that thoughts are neural ... Conscious and nonconscious thought: Insights from the neuroscience of decision-making doi:10.1073/pnas.2601239123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Michael N. ShadlenaDepartment of Neuroscience, Columbia University, New York, NY 10027bHHMI, Chevy Chase, MD 20815cZuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2601239123 https://www.pnas.org/doi/abs/10.1073/pnas.2601239123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2535704123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceReading is an essential skill, yet some deaf children face reading challenges due to reduced access to signed or spoken language. In hearing children, successful reading depends on abstract phonological representations, but whether spoken ... Reading ability in both deaf and hearing adults is linked to neural representations of abstract phonology derived from visual speech doi:10.1073/pnas.2535704123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Samuel EvansCathy J. PriceJörn DiedrichsenTae TwomeyIndie BeedieMaggie FraserMairéad MacSweeneyahttps://ror.org/02jx3x895Institute of Cognitive Neuroscience, University College London, London WC1N 3AZ, United Kingdombhttps://ror.org/02jx3x895Deafness Cognition and Language Research Centre, Division of Psychology and Language Sciences, University College London, London WC1H 0PD, United Kingdomchttps://ror.org/02jx3x895Department of Imaging Neuroscience, Queen Square Institute of Neurology, University College London, WC1N 3AR, United KingdomdWestern Institute for Neuroscience, Western University, London, ON N6A 3K7, CanadaeDepartment of Computer Science, Western University, London, ON N6A 5B7, CanadafDepartment of Statistical and Actuarial Sciences, Western University, London, ON N6A 5B7, Canada Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2535704123 https://www.pnas.org/doi/abs/10.1073/pnas.2535704123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2517683123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceMicrotubule severing enzymes are critical in diverse cellular processes. Reconstitution experiments revealed that severing enzymes extract tubulin subunits and catalyze repair with fresh tubulin, creating islands formed of tubulin bound to ... Tubulin flux at spastin-induced nanodamage sites regulates microtubule rescue frequency and EB1 lifetimes doi:10.1073/pnas.2517683123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Ewa SzczesnaJeffrey O. SpectorStephanie L. SarbanesJiayi ChenAgnieszka SzykAntonina Roll-MecakaCell Biology and Biophysics Unit, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892bBiochemistry and Biophysics Center, National Heart, Lung and Blood Institute, Bethesda, MD 20892 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2517683123 https://www.pnas.org/doi/abs/10.1073/pnas.2517683123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2531407123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceTo ensure sensory information can be passed down from the sensory neurons to the interneurons that control the motor output, the sensory-motor circuit must be robust against genetic perturbations. However, the mechanisms underlying such ... Synaptic and neural pathway redundancy enables the robustness of a sensory-motor reflex and promotes predation escape in Caenorhabditis elegans doi:10.1073/pnas.2531407123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Haoming HeEugenia King Hin FongSandeep KumarHo Ming Terence LeeAndrew M. LeiferMartin ChalfieChaogu ZhengaSchool of Biological Sciences, The University of Hong Kong, Hong Kong SAR, ChinabPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544cDepartment of Physics, Princeton University, Princeton, NJ 08544dDepartment of Biological Sciences, Columbia University, New York, NY 10027 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2531407123 https://www.pnas.org/doi/abs/10.1073/pnas.2531407123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2518376123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceThe voltage-gated proton channel Hv1 regulates diverse physiological processes, including pH homeostasis in sperm and cancer cells, bone resorption by osteoclasts, and reactive oxygen species production in immune cells. Despite its importance,... A negative-hydrated constriction zone is revealed in the active state of the Hv1 channel doi:10.1073/pnas.2518376123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Juan J. Alvear-AriasDario BasaezEmerson M. CarmonaLuciano GaliziaMiguel FernandezAntonio Peña-PichicoiMarcelo OzuOrlando JorqueraRamón LatorreAlan NeelyJose Antonio GarateCarlos Gonzalezahttps://ror.org/0081fs513Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Biodiversidad y Biología Experimental, Buenos Aires C1428EGA, Argentinabhttps://ror.org/03cqe8w59Instituto de Biodiversidad y Biología Experimental y Aplicada, Universidad de Buenos Aires y Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires C1428EGA, ArgentinacMillenium Nucleus in NanoBioPhysics, Santiago 8580702, ChiledCentro Interdisciplinario de Neurociencia de Valparaíso, Universidad de Valparaíso, Valparaíso 2381850, Chileehttps://ror.org/00cvxb145Department of Neurobiology and Biophysics, University of Washington, Seattle, WA 98106fFederal University of Southern of Bahia, Center for Training in Environmental Sciences, Porto Seguro 45810-00, Brazilghttps://ror.org/04jrwm652Facultad de Ingeniería, Universidad San Sebastián, Santiago 8580702, Chilehhttps://ror.org/04jrwm652Centro Científico y Tecnológico de Excelencia Ciencia y Vida, Universidad San Sebastián, Santiago 8580702, Chile Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2518376123 https://www.pnas.org/doi/abs/10.1073/pnas.2518376123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2516655123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceWe show that people often fail to notice the absence of minority group members from social settings, even when this absence is meaningful and consequential. This blindness to minority absence arises from a fundamental cognitive tendency—we are ... Blindness to minority absence doi:10.1073/pnas.2516655123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Rasha KardoshAsael Y. SklarKalman VictorBella Qing DongAshi D. SchwartzGal ChenRan R. HassinYaacov Tropeahttps://ror.org/0190ak572Department of Psychology, New York University, New York, NY 10003bhttps://ror.org/01px5cv07Department of Management, Arison School of Business, Reichman University, Herzliya, Israel 4610101cDepartment of Psychology, The Hebrew University, Jerusalem 9190501, Israel Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2516655123 https://www.pnas.org/doi/abs/10.1073/pnas.2516655123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2533390123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceAqueous zinc (Zn) batteries hold tremendous potential for grid-scale energy storage—owing to their affordability and intrinsic safety—yet their cycle life is substantially limited by the parasitic hydrogen evolution reaction (HER) and the ... Atomic layer-deposited nucleation layers to control zinc morphology and suppress hydrogen evolution doi:10.1073/pnas.2533390123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Ajay RaviSanzeeda Baig ShuchiGuangxia FengYuqi LiPu ZhangJunyan LiTzu-Ling LiuGiulio D’AcuntoAngela CaiTony LiKenzie M. Sanroman GutierrezZaichun LiuJing WangGe ZhangJun Ho LeeJunyoung LeeXueer XuXun GuanXueli ZhengStacey F. BentYi Cuiahttps://ror.org/00f54p054Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305bhttps://ror.org/00f54p054Department of Chemical Engineering, Stanford University, Stanford, CA 94305chttps://ror.org/05gzmn429Stanford Institute for Materials and Energy Sciences, SLAC National Accelerator Laboratory, Menlo Park, CA 94025dhttps://ror.org/00f54p054Department of Energy Science and Engineering, Stanford University, Stanford, CA 94305 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2533390123 https://www.pnas.org/doi/abs/10.1073/pnas.2533390123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2424377123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceChronic obstructive pulmonary disease (COPD) is one of the deadliest diseases worldwide. Genetic and functional studies indicate that the geneHHIPis associated with COPD susceptibility, but its role in the disease is unknown. In this work, ... HHIP’s dynamic role in epithelial wound healing reveals a potential mechanism of COPD susceptibility doi:10.1073/pnas.2424377123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Dávid DeriteiWardatul Jannat AnamikaAnny Xiaobo ZhouJeong H. YunMaor SaulerMichael H. ChoEdwin K. SilvermanErzsébet Ravasz ReganKimberly Glassahttps://ror.org/04b6nzv94Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02215bDivision of Pulmonary and Critical Care Medicine, Department of Medicine, School of Medicine, University of Virginia, Charlottesville, VA 22903cPulmonary, Critical Care, and Sleep Medicine, Yale School of Medicine, New Haven, CT 06520-8057dhttps://ror.org/029zqs055Biochemistry and Molecular Biology, Department of Biology, The College of Wooster, Wooster, OH 44691 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2424377123 https://www.pnas.org/doi/abs/10.1073/pnas.2424377123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2530750123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceHuman cumulative culture depends on our ability to innovate. While most research emphasizes how social learning spreads and preserves innovations, the cognitive processes that generate them remain poorly understood. Our study shows how ... Semantic knowledge guides innovation and drives cultural evolution doi:10.1073/pnas.2530750123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Anil YamanShen TianBjörn LindströmaComputer Science Department, Vrije Universiteit Amsterdam, Amsterdam 1081 HV, The NetherlandsbDepartment of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm 171 77, Sweden Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2530750123 https://www.pnas.org/doi/abs/10.1073/pnas.2530750123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2520561123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceMapping sequence–function landscape of target protein is fundamental to protein engineering and to a deeper understanding of protein function. While the effect of a single mutation is often studied, the impact of combining multiple mutations ... Navigating high-order protein fitness landscapes via deep learning on directed evolution trajectories doi:10.1073/pnas.2520561123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Chengzhi SongLiang MaLingfeng XueYingfan XuQihan ZhangYuxi LiuChen SongYihan LinaCenter for Quantitative Biology and Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, ChinabThe Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, School of Life Sciences, Peking University, Beijing 100871, ChinacPeking University Chengdu Academy for Advanced Interdisciplinary Biotechnologies, Chengdu, Sichuan 610213, China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2520561123 https://www.pnas.org/doi/abs/10.1073/pnas.2520561123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2525164123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceThe EBV EBNA2 protein is required for EBV-induced transformation of B cells in vitro and drives transcription of the viral promoters used in type III latency. However, most EBV+ lymphomas in immunocompetent humans do not express EBNA2 (likely ... Epstein–Barr virus (EBV) infection causes human germinal center B cell–derived lymphomas in the absence of EBNA2 expression doi:10.1073/pnas.2525164123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Chunyan WangJillian A. BristolScott E. NelsonTony ChenCharlotte HendricksonDana C. BaiuMariah RielMitch HayesErik A. RanheimJenny E. GumperzEric C. JohannsenShannon C. KenneyaDepartment of Oncology, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53706bDepartment of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53706cDepartment of Pathology, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53706dDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53706 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2525164123 https://www.pnas.org/doi/abs/10.1073/pnas.2525164123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2531920123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceSex differences are consistently described in the incidence and severity of major depressive disorder. However, the drivers of these disparities are difficult to disentangle. Our model, the Four Core Genotypes mice, allows us to differentiate ... Impact of sex chromosomes and gonad type in stress susceptibility in corticostriatal brain regions doi:10.1073/pnas.2531920123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Kelly N. BarkoMicah A. SheltonDawson R. KroppThien Quy PhamJennifer R. RainvilleXiangning XueGeorge C. TsengGeorgia E. HodesMarianne L. SeneyaDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213bCenter for Neuroscience at University of Pittsburgh, Pittsburgh, PA 15261cSchool of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061dDepartment of Biostatistics, University of Pittsburgh, Pittsburgh, PA 15261 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2531920123 https://www.pnas.org/doi/abs/10.1073/pnas.2531920123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2522060123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceThis report establishes three key findings. First, that the enzymatic oxidation of thymidine (T) by 5-methylpyrimidine dioxygenases (5mYOXs) occurs in nature outside eukaryotes, with bacteriophage enzymes exhibiting postreplicative and ... Uncovering ParB-dependent and -independent subclasses of T-dioxygenases from bacteriophage doi:10.1073/pnas.2522060123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Katherine H. O’TooleLydia J. PerkinsAuriane BouchetMia L. DeSanctisSean R. LundAndrew J. MulhollandYahya El HaririSabaa BelkadiHarold W. BellDavid M. HoughLana SalehaResearch Department, Biochemistry and Microbiology Division, New England Biolabs, Ipswich, MA 01938 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2522060123 https://www.pnas.org/doi/abs/10.1073/pnas.2522060123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2528977123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceNanophase metallic iron (npFe0) in lunar impact glass provides key information about the space weathering process. However, lack of three-dimensional structures and morphologies has hampered our understanding about the occurrence and formation ... 3D insights into the multiorigins of nanophase Fe0 in the Moon surface doi:10.1073/pnas.2528977123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Yiheng DaiZezhou LiTianyi JiaZhiheng XieRuimin WangZongjun YinBing ShenJihan Zhouahttps://ror.org/02601yx74Beijing National Laboratory for Molecular Sciences, Center for Integrated Spectroscopy, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, Chinabhttps://ror.org/02v51f717Research Institute of Extraterrestrial Material at Peking University, Beijing 100871, Chinachttps://ror.org/02v51f717Ministry of Education Key Laboratory of Orogenic Belts and Crustal Evolution, School of Earth and Space Sciences, Peking University, Beijing 100871, Chinadhttps://ror.org/034t30j35State Key Laboratory of Palaeobiology and Stratigraphy, Nanjing Institute of Geology and Palaeontology, Chinese Academy of Sciences, Nanjing 210008, China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2528977123 https://www.pnas.org/doi/abs/10.1073/pnas.2528977123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2528144123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceGene editing therapy holds the promise to cure diseases in a single treatment, but is hindered by suboptimal delivery vectors. In this study, we develop an easy-to-operate synthetic chemistry enabling the plug-and-play assembly of diverse ... Plug-and-play assembly of biodegradable ionizable lipids for potent mRNA delivery and gene editing in vivo doi:10.1073/pnas.2528144123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Xuexiang HanYing XuAdele S. RicciardiJunchao XuYan XiangRohan PalankiVivek ChowdharyLulu XueNingqiang GongMohamad-Gabriel AlamehWilliam H. PeranteauJames M. WilsonDaniel RekerDrew WeissmanMichael J. Mitchellahttps://ror.org/00b30xv10Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104bhttps://ror.org/05qbk4x57State Key Laboratory of RNA Innovation, Science and Engineering, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, Chinachttps://ror.org/00b30xv10Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104dhttps://ror.org/00b30xv10Penn Institute for RNA Innovation, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104ehttps://ror.org/02n96ep67School of Pharmacy, East China Normal University, Shanghai 200062, Chinafhttps://ror.org/01z7r7q48Division of Pediatric General, Thoracic, and Fetal Surgery, The Center for Fetal Research, Children’s Hospital of Philadelphia, Philadelphia, PA 19104ghttps://ror.org/00py81415Department of Biomedical Engineering, Duke University, Durham, NC 27705hhttps://ror.org/00b30xv10Gene Therapy Program, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104ihttps://ror.org/00b30xv10Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104jhttps://ror.org/00b30xv10Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104khttps://ror.org/00b30xv10Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104lhttps://ror.org/00b30xv10Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104mhttps://ror.org/00b30xv10Center for Precision Engineering for Health, University of Pennsylvania, Philadelphia, PA 19104 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2528144123 https://www.pnas.org/doi/abs/10.1073/pnas.2528144123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2535714123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceNature in cities can enhance human well-being by delivering benefits like cooling, clean air and water, and opportunities for recreation and contemplation. Yet natural green (vegetation) and blue (surface water) spaces may not be equally ... Accessibility–equality dynamics in urban blue and green spaces reshape human well-being doi:10.1073/pnas.2535714123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Bin XueJianing ZhangBingsheng LiuMarina AlbertiYufeng FanDong ZhaoNancy B. GrimmaDepartment of Land Resources and Urban Development Management, School of Public Policy and Administration, Chongqing University, Chongqing 400044, ChinabSchool of Life Sciences, Arizona State University, Tempe, AZ 85287-4501cDepartment of Construction Management and Operations & Maintenance, School of Economics and Management, Hebei University of Technology, Tianjin 300401, ChinadDepartment of Urban Design and Planning, University of Washington, Seattle, WA 98195eDepartment of Civil & Environmental Engineering, School of Planning, Design and Construction, Michigan State University, East Lansing, MI 48824 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2535714123 https://www.pnas.org/doi/abs/10.1073/pnas.2535714123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2610968123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceAging is characterized by the progressive loss of stem cell function and tissue homeostasis. Using the invertebrate chordateBotryllus schlosseri, we demonstrate that brief pulsatile electrical current (PEC) induces long-lasting rejuvenation. ... Electrical stimulation promotes longevity and regeneration in a colonial chordate doi:10.1073/pnas.2610968123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Jos DomenYotam VoskoboynikTom LevyErica M. DomenKatherine J. IshizukaKarla J. PalmeriChiara AnselmiThomas RolanderNorma F. NeffAngela M. DetweilerIrving L. WeissmanKimberly L. GandyDebashis SahooAyelet Voskoboynikahttps://ror.org/00f54p054Biology Department, Stanford University, Hopkins Marine Station, Pacific Grove, CA 93950bhttps://ror.org/00f54p054Department of Pathology and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305chttps://ror.org/0168r3w48Department of Bioinformatics and System Biology, Jacobs School of Engineering, University of California, San Diego, CA 92093dhttps://ror.org/01an7q238Department of Integrative Biology, University of California, Berkeley, CA 94704ehttps://ror.org/00knt4f32Chan Zuckerberg Biohub SF, San Francisco CA 94158fhttps://ror.org/0168r3w48Department of Pediatrics, University of California, San Diego, CA 92093ghttps://ror.org/0168r3w48Department of Computer Science and Engineering, Jacob’s School of Engineering, University of California, San Diego, CA 92093 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2610968123 https://www.pnas.org/doi/abs/10.1073/pnas.2610968123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2606868123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceAcross animal species, injured tissues activate ERK signaling to trigger gene expression changes needed for healing or regeneration. However, it is not clear whether the process linking tissue damage to ERK is well conserved—involving shared ... Acoel whole-body regeneration begins with spreading, multi-tissue ERK signaling downstream of neuregulin-1 doi:10.1073/pnas.2606868123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Catriona BreenMansi Srivastavaahttps://ror.org/03vek6s52Department of Organismic and Evolutionary Biology, Museum of Comparative Zoology, Harvard University, Cambridge, MA 02138 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2606868123 https://www.pnas.org/doi/abs/10.1073/pnas.2606868123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2535412123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceAs the central kinase in antiviral innate immunity, the activation of TANK-binding kinase 1 (TBK1) must be tightly controlled. However, how host metabolic pathways directly regulate TBK1 activity remains poorly understood. In this study, we ... Phosphoethanolamine cytidylyltransferase 2 integrates DAG metabolism and TBK1 activation to regulate antiviral innate immunity doi:10.1073/pnas.2535412123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Wencong LaiZengjie LiuHan HuWanxuan ZhangBaolin LiRui WangZengqi ZhaoXueshan LiYihang HuJinwei DuanDan XuYongtao LiuXianyong BuJianlong DuBingyuan YangXiao TangYueru LiMin WanYanjiao ZhangHuihui ZhouKangsen MaiQinghui Aiahttps://ror.org/04rdtx186Key Laboratory of Aquaculture Nutrition and Feed (Ministry of Agriculture and Rural Affairs), Key Laboratory of Mariculture (Ministry of Education), Ocean University of China, Qingdao 266003, People’s Republic of ChinabLaboratory for Marine Fisheries Science and Food Production Processes, Qingdao Marine Science and Technology Center, Qingdao 266237, People’s Republic of China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2535412123 https://www.pnas.org/doi/abs/10.1073/pnas.2535412123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2603282123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceEndophytic insect pathogenic fungi play dual roles as plant mutualists and insect pathogens, transferring insect-derived nitrogen to plants and contributing substantially to ecosystem nitrogen cycling. Despite their importance, the mechanisms ... Volatile signaling in plant–Metarhizium–insect interactions: Implications for nitrogen cycling doi:10.1073/pnas.2603282123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Xingyuan TangTing FengChaonan YuMeihong NiYubo ZhangXin MaXinmiao WangJiani ChenWenqi ShiRaymond J. St.LegerJianhua HuangWeiguo FangaState Key Laboratory of Vegetation structure, Function and Construction (VegLab), College of Life Science, Zhejiang University, Hangzhou 310058, Chinabhttps://ror.org/00a2xv884Institute of Insect Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310058, Chinachttps://ror.org/047s2c258Department of Entomology, University of Maryland, College Park, MD 20742 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2603282123 https://www.pnas.org/doi/abs/10.1073/pnas.2603282123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2536003123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceCRISPR technologies are typically engineered in bacteria, even when they must function in the far more complex environment of human cells. This gap has limited the discovery of variants with improved DNA recognition or with resistance to ... Anti-CRISPR-mediated continuous directed evolution of CRISPR-Cas9 in human cells doi:10.1073/pnas.2536003123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Andrew L. SabolAmanuella A. MengistePrashant SinghVedagopuram SreekanthSamuel J. HendelMinh Thuan Nguyen TranAnton M. BarybinSantosh ChaudharyRa’Mal M. HarrisKristi E. LiivakZachary C. SeveranceCale M. LociceroKarishma KailassChaiheon LeeLucy Qinghua XuVincent L. ButtyAmit ChoudharyMatthew D. ShouldersaDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139bBroad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142cKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139dDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139eBioMicro Center, Massachusetts Institute of Technology, Cambridge, MA 02139fDivision of Renal Medicine, Brigham and Women’s Hospital, Boston, MA 02115gDivision of Engineering in Medicine, Brigham and Women’s Hospital, Boston, MA 02115hDepartment of Medicine, Harvard Medical School, Boston, MA 02115 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2536003123 https://www.pnas.org/doi/abs/10.1073/pnas.2536003123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2601012123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceVirtually all cells in the body contain circadian oscillators, yet how circadian timing is organized across diverse cell types within complex organs remains poorly understood. Here, we developed a cell type–specific circadian reporter system ... Not all gut cellular circadian oscillators are food entrainable doi:10.1073/pnas.2601012123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Isabel MagañaS. K. Tahajjul TaufiqueYongli ShanMelody ShenDavid E. EhichioyaJoseph S. TakahashiShin YamazakiYuuki Obataahttps://ror.org/05byvp690Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX 75390bhttps://ror.org/05byvp690Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390chttps://ror.org/05byvp690Peter O’Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2601012123 https://www.pnas.org/doi/abs/10.1073/pnas.2601012123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2522754123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceSynaptic plasticity, the ability of synapses to change their strength in response to activity, is fundamental to learning and memory, and is accompanied by changes in the presynaptic terminal and the postsynaptic spine. Here, three-dimensional ... Transition of the presynaptic vesicle cluster from a compact to dispersed organization during long-term potentiation doi:10.1073/pnas.2522754123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Guadalupe C. GarciaThomas M. BartolLyndsey M. KirkPriyal BadalaKristen M. HarrisTerrence J. Sejnowskiahttps://ror.org/03xez1567Computational Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037bhttps://ror.org/00hj54h04Department of Neuroscience, Center for Learning and Memory, Institute for Neuroscience, University of Texas at Austin, Austin, TX 78712chttps://ror.org/0168r3w48Department of Neurobiology, University of California, San Diego, La Jolla, CA 92037 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2522754123 https://www.pnas.org/doi/abs/10.1073/pnas.2522754123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2601534123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceSelf-accelerating turbidity currents are powerful, erosive gravity underflows that sever intercontinental telecommunication cables and reshape subaqueous landscapes. Despite their significance, direct field observations of their growth and ... In situ evidence of self-accelerating turbidity currents doi:10.1073/pnas.2601534123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Hongbo MaGefei DengXingyu ChenYuanjian WangBrandon McElroyJeffrey NittrouerYu ZhangToshiki IwasakiMatthieu CartignyXudong FuaDepartment of Hydraulic Engineering, Tsinghua University, Beijing 100084, ChinabDepartment of Civil and Environmental Engineering, Ven Te Chow Hydrosystems Laboratory, The Grainger College of Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801cYellow River Institute of Hydraulic Research, Key Laboratory of the Yellow River, Zhengzhou 450003, ChinadDepartment of Geology and Geophysics, University of Wyoming, Laramie, WY 82071eDepartment of Geosciences, Texas Tech University, Lubbock, TX 79409fDepartment of Civil Engineering, Hokkaido University, Sapporo, Hokkaido 060-0808, JapangDepartment of Geography, Durham University, Durham DH1 3LE, United Kingdom Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2601534123 https://www.pnas.org/doi/abs/10.1073/pnas.2601534123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2533420123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceTeams living and working in isolated, confined, and extreme (ICE) environments—such as Antarctic stations or future missions to the Moon and Mars—face unique psychological and social challenges. Yet longitudinal, high-resolution data on how ... Social interactions in isolated, confined, and extreme environments: A study of Antarctic winter teams using wearable sensors doi:10.1073/pnas.2533420123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Andrea CantisaniJan B. SchmutzPedro Marques-QuinteiroLorenzo Dall’AmicoCiro CattutoMirko AntinoWalter J. EppichKatharina StegmayerSebastian WaltheraTranslational Research Center, University Hospital of Psychiatry and Psychotherapy, Bern 3000, SwitzerlandbSanatorium Kilchberg, Private Clinic for Psychiatry and Psychotherapy, Kilchberg 8802, SwitzerlandcDepartment of Psychology, University of Zurich, Zurich 8050, SwitzerlanddIntrepid Lab, School of Economic Sciences and Organizations, Lusófona University, Lisboa 1749-024, PortugaleCentre for Transdisciplinary Development Studies, Universidade de Trás-os Montes e Alto Douro, Vila Real 5000-801, PortugalfInstitute for Scientific Interchange Foundation, Torino 10123, ItalygDepartment of Methodology for Behavioral Sciences, Universidad Complutense de Madrid, Madrid 28040, SpainhFaculty of Medicine, Dentistry, and Health Sciences, University of Melbourne, Melbourne, VIC 3010, AustraliaiDepartment of Psychiatry, Psychosomatics, and Psychotherapy, Center of Mental Health, University Hospital of Würzburg, Würzburg 97080, Germany Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2533420123 https://www.pnas.org/doi/abs/10.1073/pnas.2533420123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2605194123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceVaccinia virus encodes decapping enzymes that promote rapid turnover of mRNA and double-stranded RNA (dsRNA) through coordinating with host degradation factor. Here, we show that dysfunctional RNA degradation in vaccinia virus–infected cells ... Perturbation of RNA homeostasis impairs mitochondrial respiration during poxvirus infection through excess RNA accumulation doi:10.1073/pnas.2605194123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Djamal Brahim BelhaouariAnil PantSantiago Navarro-ForeroFernando CantuZhilong YangaDepartment of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843bDivision of Biology, Kansas State University, Manhattan, KS 66506 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2605194123 https://www.pnas.org/doi/abs/10.1073/pnas.2605194123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2522067123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificancePolyploid cells are life’s stress responders as the more than doubling of a cell’s genome has been shown to enable resistance to genotoxic stress. Cells are exposed to various sources of genotoxic stress, including ultraviolet light. Here, we ... Epithelial cell fusion is required for tissue repair following UV-A irradiation doi:10.1073/pnas.2522067123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Minqi ShenLillie G. MitchellLydia W. BoerLydia M. BischoffVicki P. LosickaBiology Department, Morrissey College of Arts and Sciences, Boston College, Chestnut Hill, MA 02647 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2522067123 https://www.pnas.org/doi/abs/10.1073/pnas.2522067123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2522077123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceUnderstanding the mechanism that links whole genome doubling (WGD), extra centrosomes, and tumorigenesis to one another is crucial to understanding tumor progression, as many human tumors have a high incidence of WGD and extra centrosomes. ... Oxidative stress and serum deprivation influence the evolution of newly formed tetraploid cells during tumorigenesis doi:10.1073/pnas.2522077123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Megan L. SweetMathew BloomfieldNicholas KeenNazia BanoXiang PanNicolaas C. BaudoinBarath UdayasuryanRaffae N. AhmadEva RiddervoldErica KlaiberScott S. VerbridgeEva M. SchmelzJing ChenDaniela CiminiaDepartment of Biological Sciences and Fralin Life Sciences Institute, Virginia Tech, Blacksburg, VA 24061bVirginia Tech Translational Biology, Medicine, and Health graduate program, Blacksburg, VA 24061cDepartment of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, VA 24061dDepartment of Biomedical Engineering and Mechanics, Virginia Tech, Blacksburg, VA 24061eVirginia Tech Center for Soft Matter and Biological Physics, Blacksburg, VA 24061fVirginia Tech Center for the Mathematics of Biosystems, Blacksburg, VA 24061 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2522077123 https://www.pnas.org/doi/abs/10.1073/pnas.2522077123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2522068123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceDiverse displays of ploidy, the number of complete sets of chromosomes, are observed in cardiomyocytes (CM) across the animal kingdom, yet the mechanisms that govern CM ploidy remain elusive. Here, we perform genome-wide association mapping ... Genome-wide association mapping and targeted loss of function studies identify Shroom3 as a driver of hyperpolyploidy and ventricular dilation doi:10.1073/pnas.2522068123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Alexandra L. PurdyAmirala Bakhshian NikAnooj A. ArkatkarProttoy HasanMichael A. FlinnPriyanka ChoudhuryCheyret WoodAkiko TakizawaLynn MalloyMonika TutajThomas A. DrysdaleDarren BridgewaterBrian A. LinkTimothy F. PlagemanAnne E. KwitekMelinda R. DwinellLaura M. SabaCaitlin C. O’MearaMichaela Pattersonahttps://ror.org/00qqv6244Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226bhttps://ror.org/00qqv6244Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226chttps://ror.org/00qqv6244Cardiovascular Research Center, Medical College of Wisconsin, Milwaukee, WI 53226dhttps://ror.org/03wmf1y16Center for Innovative Design and Analysis, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO 80045ehttps://ror.org/038pa9k74Children’s Health Research Institute, Victoria Research Labs, London, ON N6A 4L6, Canadafhttps://ror.org/02grkyz14Department of Physiology and Pharmacology, The University of Western Ontario, London, ON N6A 3K7, Canadaghttps://ror.org/02grkyz14Department of Paediatrics, The University of Western Ontario, London, ON N6A 3K7, Canadahhttps://ror.org/02fa3aq29Department of Pathology and Molecular Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON L8S 4L8, Canadaihttps://ror.org/00rs6vg23College of Optometry, The Ohio State University, Columbus, OH 43210jhttps://ror.org/03wmf1y16Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO 80045 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2522068123 https://www.pnas.org/doi/abs/10.1073/pnas.2522068123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2522071123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificancePolyploidy, having multiple copies of the entire set of chromosomes, underpins major innovations in both animals and plants and fuels biodiversity. Yet, why some polyploid lineages are successful while others fail remains unclear. Our study ... Ecological opportunity and the onset of polyploid niche expansion waves doi:10.1073/pnas.2522071123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Felipe KauaiYves Van de PeerDries BonteaDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, BelgiumbCenter for Plant Systems Biology, Bioinformatics and Evolutionary Genomics, VIB, 9052 Ghent, BelgiumcDepartment of Biology, Terrestrial Ecology Unit, Ghent University, 9000 Ghent, BelgiumdCenter for Microbial Ecology and Genomics, Department of Biochemistry, Genetics and Microbiology, University of Pretoria, Pretoria 0028, South AfricaeCollege of Horticulture, Academy for Advanced Interdisciplinary Studies, Nanjing Agricultural University, Nanjing 210095, China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2522071123 https://www.pnas.org/doi/abs/10.1073/pnas.2522071123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2535311123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceDisputes are central to scientific progress, but their resolution can be difficult. Adversarial collaboration offers a powerful but underexplored method for addressing scientific debate. We offer proof of concept that an AI-assisted ... AI assists adversarial collaboration in debate on minority salience doi:10.1073/pnas.2535311123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Barbara MellersLeo YuanYubo ZhouIsabelle MauboussinEyana C. LaoBea CorioVille SatopaaLyle UngarSudeep BhatiaCory J. ClarkRasha KardoshRan HassinAsael SklarSurya GayetChris PaffenStefan Van der StigchelAndre SahakianPhilip TetlockaPsychology and Marketing Department, University of Pennsylvania, Philadelphia, PA 19104bPsychology Department, University of Pennsylvania, Philadelphia, PA 19104cTechnology and Operations Management, Institut europeen d‘administration des affaires, Fontainebleau Cedex 77305, FrancedComputer and Information Sciences, University of Pennsylvania, Philadelphia, PA 19104eNew College of Florida, Sarasota, FL 34243fPsychology Department, New York University, New York, NY 10003gDepartment of Psychology, The Hebrew University of Jerusalem, Jerusalem 9190500, IsraelhArison School of Business, Reichman University, Herzliya 4610101, IsraeliExperimental Psychology, Helmholtz Institute, Utrecht University, Utrecht 3584 CS, The NetherlandsjManagement Department and Psychology Department, University of Pennsylvania, Philadelphia, PA 19104 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2535311123 https://www.pnas.org/doi/abs/10.1073/pnas.2535311123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2604142123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificancePair density waves are an unusual form of superconductivity in which the superconducting order varies periodically in space, but phase-sensitive evidence for their microscopic nature has remained limited. Here, we use normal and Josephson ... Phase-sensitive evidence for pair density waves in a kagome superconductor doi:10.1073/pnas.2604142123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Xiao-Yu YanGuowei LiuHanbin DengXitong XuHaiyang MaHailang QinJunyi ZhangYuanyuan ZhaoXiuhao FanWei SongMuwei GaoHaitian ZhaoZhe QuYigui ZhongKozo OkazakiXiquan ZhengYingying PengZurab GuguchiaXianxin WuDa WangQiang-Hua WangHendrik HohmannMatteo DürrnagelRonny ThomaleJia-Xin Yinahttps://ror.org/049tv2d57State Key Laboratory of Quantum Functional Materials, Department of Physics, and Guangdong Basic Research Center of Excellence for Quantum Science, Southern University of Science and Technology, Shenzhen 518055, ChinabQuantum Science Center of Guangdong-Hong Kong-Macao Greater Bay Area, Shenzhen 518045, Chinad William H. Miller III Department of Physics and Astronomy, Johns Hopkins University, Baltimore, MD 21218chttps://ror.org/034t30j35Anhui Key Laboratory of Low-Energy Quantum Materials and Devices, High Magnetic Field Laboratory (CHMFL), Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, Chinadhttps://ror.org/00za53h95William H. Miller III Department of Physics and Astronomy, Johns Hopkins University, Baltimore, MD 21218ehttps://ror.org/057zh3y96Institute for Solid State Physics, The University of Tokyo, Kashiwa, Chiba 277-8581, Japanfhttps://ror.org/02v51f717International Center for Quantum Materials, School of Physics, Peking University, Beijing 100871, ChinagPSI Center for Neutron and Muon Sciences, Villigen PSI 5232, Switzerlandhhttps://ror.org/034t30j35Theoretical Physics, Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 100190, Chinaihttps://ror.org/01rxvg760National Laboratory of Solid State Microstructures, School of Physics, Nanjing University, Nanjing 210093, Chinajhttps://ror.org/00fbnyb24Institute for Theoretical Physics and Astrophysics, University of Würzburg, Würzburg 97074, Germanykhttps://ror.org/05a28rw58Institute for Theoretical Physics, ETH Zürich, Zürich 8093, Switzerland Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2604142123 https://www.pnas.org/doi/abs/10.1073/pnas.2604142123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2529668123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceWe examine how peer influence shaped the choices of allegiance among West Point cadets during the American Civil War. Leveraging newly assembled historical data and modern inference methods, we provide causal evidence that peer effects remain ... Peer influence on West Point cadets’ Civil War allegiances doi:10.1073/pnas.2529668123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Yuchen GuoMatthew O. JacksonRuixue Jiaahttps://ror.org/00t33hh48Department of Economics, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, Chinabhttps://ror.org/0168r3w48The Chinese University of Hong Kong–University of California San Diego Joint Laboratory on Chinese Economy, Shatin, New Territories, Hong Kong SAR, Chinachttps://ror.org/00f54p054Department of Economics, Stanford University, Stanford, CA 94305dhttps://ror.org/01arysc35Santa Fe Institute, Santa Fe, NM 87501ehttps://ror.org/0168r3w48School of Global Policy and Strategy, University of California San Diego, La Jolla, CA 92093fhttps://ror.org/04jzmdh37Centre for Economic Policy Research, London EC1R 5HL, United Kingdomghttps://ror.org/04grmx538National Bureau of Economic Research, Cambridge, MA 02138 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2529668123 https://www.pnas.org/doi/abs/10.1073/pnas.2529668123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2533269123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceEcological communities are complex and dynamic systems and their composition—as well as changes in that—are difficult to predict. This is a major challenge especially with microbes, key players for example in global biogeochemical cycles and ... Evolution induced state shifts in a long-term microbial community experiment doi:10.1073/pnas.2533269123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Mikko KivikoskiJohannes CairnsShane L. HogleSanna PausioLutz BecksVille MustonenTeppo Hiltunenahttps://ror.org/040af2s02Department of Computer Science, University of Helsinki, Helsinki 00014, Finlandbhttps://ror.org/040af2s02Department of Organismal and Evolutionary Biology, University of Helsinki, Helsinki 00014, Finlandchttps://ror.org/05vghhr25Turku Collegium for Science, Medicine and Technology, University of Turku, Turku 20014, Finlanddhttps://ror.org/05vghhr25Department of Biology, University of Turku, Turku 20014, Finlandehttps://ror.org/0546hnb39Aquatic Ecology and Evolution, Department of Biology, University of Konstanz, Konstanz 78464, Germany Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2533269123 https://www.pnas.org/doi/abs/10.1073/pnas.2533269123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2606206123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceThe four serotypes of dengue virus (DENV1-4) pose a major threat to public health worldwide. The paradigm that individuals can be infected only once per lifetime by each serotype has been challenged by reports of homotypic reinfections; ... Long-term antibody dynamics challenge the paradigm of lifelong homotypic immunity to dengue virus doi:10.1073/pnas.2606206123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Jair AndradeAdrien Mitard de GirardierAngkana T. HuangDarunee BuddhariMarco Hamins-PuertolasMaria-Theresa AleraMary Noreen ChuaTaweewun HunsawongDerek A. T. CummingsStephen ThomasHeather FribergJeffrey R. CurrierAdam WaickmanAaron FarmerIn-Kyu YoonKathryn AndersonAlan L. RothmanHenrik Saljeahttps://ror.org/013meh722Department of Genetics, University of Cambridge, Cambridge CB23EH, United Kingdombhttps://ror.org/023swxh49Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok 10400, Thailandchttps://ror.org/040kfrw16Microbiology and Immunology, State University of New York Upstate Medical University, Syracuse, NY 13210dhttps://ror.org/043mz5j54School of Medicine, University of California, San Francisco, CA 94143eChong Hua Hospital, Cebu City 6000, PhilippinesfDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205ghttps://ror.org/0145znz58Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD 20910hhttps://ror.org/02yfanq70International Vaccine Institute, Seoul 08826, South Koreaihttps://ror.org/013ckk937Institute for Immunology and Informatics, Department of Cell and Molecular Biology, University of Rhode Island, Providence, RI 02903 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2606206123 https://www.pnas.org/doi/abs/10.1073/pnas.2606206123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2530090123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceNatural protein shells such as viral capsids and bacterial microcompartments have inspired efforts to design synthetic compartments that protect and deliver functional molecules. Here, we show that a nonviral, artificially evolved nucleocapsid ... An engineered closed-shell, two-component, 480-subunit nucleocapsid doi:10.1073/pnas.2530090123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Mikail D. LevasseurNaohiro TerasakaAngela SteinauerStephan TetterSara PfisterBeat H. MeierDonald Hilvertahttps://ror.org/02q73ep21Laboratory of Organic Chemistry, ETH Zurich, Zurich 8093, Switzerlandbhttps://ror.org/01m0th787Institute of Molecular Physical Science, ETH Zurich, Zurich 8093, Switzerland Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2530090123 https://www.pnas.org/doi/abs/10.1073/pnas.2530090123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2509164123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceBesides linear sequences organized in canonical B-form helix, eukaryotic DNA can also commonly adopt non-B-form alternative conformations. G-quadruplexes (G4s) are well-described non-B-form secondary DNA structures that are highly conserved ... CTCF directly binds G-quadruplex structures to regulate genome topology and gene expression doi:10.1073/pnas.2509164123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Daniela Samaniego-CastruitaIsabella HanRoxroy C. MorganSamantha CarpenterBryce WilliamsAbhijit ChakrabortyIshwar RadhakrishnanFerhat AySamuel A. MyersAnjana RaoVipul ShuklaaDepartment of Cell and Developmental Biology, Northwestern University, Chicago, IL 60611bhttps://ror.org/05vkpd318Center for Autoimmunity and Inflammation, La Jolla Institute for Immunology, La Jolla, CA 92037cDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60201dhttps://ror.org/0168r3w48Bioinformatics and Systems Biology PhD Program, University of California, San Diego, CA 92093ehttps://ror.org/0168r3w48Department of Pediatrics, University of California San Diego, La Jolla, CA 92093fhttps://ror.org/05vkpd318Laboratory for Immunochemical Circuits, La Jolla Institute for Immunology, La Jolla, CA 92037ghttps://ror.org/05vkpd318Division of Signaling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA 92037hhttps://ror.org/0168r3w48Department of Pharmacology and Moores Cancer Center, University of California San Diego, La Jolla, CA 92093iRobert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611jCenter for Human Immunobiology, Northwestern University, Chicago, IL 60611 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2509164123 https://www.pnas.org/doi/abs/10.1073/pnas.2509164123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2604349123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceCell behavior is often highly dynamic, exhibiting periodic protrusion-retraction cycles at the leading edge that are essential for migration, immune responses, and cancer invasion. How such instability arises from mechanotransduction between ... Force loading on molecular clutches governs the stability of cell lamellipodia doi:10.1073/pnas.2604349123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Ruihao XueLezi KangYonggang ChenHaoxiang YangHongyuan JiangZe Gongahttps://ror.org/04c4dkn09Department of Modern Mechanics, University of Science and Technology of China, Hefei, Anhui 230027, Chinabhttps://ror.org/034t30j35State Key Laboratory of Nonlinear Mechanics, Institute of Mechanics, Chinese Academy of Science, Beijing 100190, China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2604349123 https://www.pnas.org/doi/abs/10.1073/pnas.2604349123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2526584123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceTwo types of status define the standing of individuals within their groups: popularity (how much they are liked) and leadership (how much they are perceived to be leaders). In any social interaction, people may track their own and their peers’ ... Neural representations of popularity and leadership status relate to conformity in daily life doi:10.1073/pnas.2526584123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Ovidia A. StanoiDanielle CosmeMia JovanovaYoona KangFaustine CorbaniAmanda L. McGowanJosé Carreras-TartakAnthony ResnickPeter S. BearmanZachary M. BoydDani S. BassettDavid M. Lydon-StaleyPeter J. MuchaEmily B. FalkKevin N. OchsneraAnnenberg School for Communication, University of Pennsylvania, Philadelphia, PA 19104bAnnenberg Public Policy Center, University of Pennsylvania, Philadelphia, PA 19104cSchool of Medicine, University of St. Gallen, St. Gallen 9000, SwitzerlanddCentre for Digital Health Interventions, Department of Management, Technology and Economics, ETH Zürich, Zurich, SwitzerlandeDepartment of Psychology, Rutgers University, Camden, NJ 08102fDepartment of Psychology, Princeton University, Princeton, NJ 08540gDepartment of Sociology, Columbia University, New York, NY 10027hDepartment of Mathematics, Brigham Young University, Provo, UT 84603iDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104jDepartment of Mathematics, Dartmouth College, Hanover, NH 03755kDepartment of Psychology, University of Pennsylvania, Philadelphia, PA 19104lWharton Business School, University of Pennsylvania, Philadelphia, PA 19104mDepartment of Psychology, Columbia University, New York, NY 10027 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2526584123 https://www.pnas.org/doi/abs/10.1073/pnas.2526584123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2537357123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceIt is often assumed that the information transfer accuracy during gene expression must be high. However, translation is relatively error-prone. Under stress conditions, bacteria can benefit from mistranslation and concomitant proteome ... Plants tolerate substantial rates of plastid mistranslation via regulated proteostasis doi:10.1073/pnas.2537357123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Benjamin BrandtSebastian SchwartzSerena SchwenkertMoritz KrämerKuenzang OmCarina EngstlerAndreas KlinglPeter JahnsEtienne H. MeyerRachael A. DeTarJürgen EirichIris FinkemeierAsaph B. CousinsHans-Henning KunzaPlant Biochemistry and Physiology, Department of Plant Sciences, Ludwig-Maximilians-University Munich, Martinsried-Planegg 82152, GermanybMass Spectrometry of Biomolecules, Department of Plant Sciences, Ludwig-Maximilians-University Munich, Martinsried-Planegg 82152, GermanycPlant Molecular Biology, Department of Plant Sciences, Ludwig-Maximilians-University Munich, Martinsried-Planegg 82152, Germanydhttps://ror.org/05dk0ce17School of Biological Sciences, Washington State University, Pullman, WA 99164-4236ePlant Development, Department of Plant Sciences, Ludwig-Maximilians-University Munich, Martinsried-Planegg 82152, GermanyfDepartment of Plant Biochemistry, Heinrich-Heine-University Duesseldorf, Duesseldorf 40225, GermanygInstitute of Plant Physiology, Martin-Luther-University Halle-Wittenberg, Halle (Saale) 06120, Germanyhhttps://ror.org/03k1gpj17Department of Biology, Colorado State University, Fort Collins, CO 80523ihttps://ror.org/00pd74e08Plant Physiology, Institute of Plant Biology and Biotechnology, University of Muenster, Muenster 48149, Germany Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2537357123 https://www.pnas.org/doi/abs/10.1073/pnas.2537357123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2537320123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceMycobacteriumabscessus(MABS) infections are increasing in prevalence in people with CF (pwCF), partly due to widespread antibiotic resistance. While functional defects in the antibacterial ability of CF macrophages have been reported, this ... Multiple defects in macrophage antibacterial responses support intracellular survival of Mycobacterium abscessus in cystic fibrosis doi:10.1073/pnas.2537320123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Abdullah A. TariqueStefan EmmingDean KelkJayden LoganDivya RamanthEmma K. DaltonKaustav Das GuptaTamara BlakeJames E. B. CursonSyeda Farhana AfrozMatthew J. SweetClaire E. WainwrightRonan KapetanovicLaurent KremerScott C. BellEmmanuelle FantinoPeter D. SlyaChildren’s Health and Environment Program, Child Health Research Centre, The University of Queensland, Brisbane, QLD 4101, AustraliabAustralian Infectious Diseases Research Centre, The University of Queensland, Brisbane, QLD 4072, AustraliacInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, AustraliadRespiratory and Sleep Medicine, Queensland Children’s Hospital, Brisbane, QLD 4101, AustraliaeInstitut national de recherche pour l’agriculture, l’alimentation et l’environnement, Université de Tours, Infectiologie et Santé Publique, Nouzilly 37380, FrancefCentre National de la Recherche Scientifique, UMR 9004, Institut de Recherche en Infectiologie de Montpellier, Université de Montpellier, Montpellier 34293, FrancegInstitut national de la santé et de la recherche médicale, Institut de Recherche en Infectiologie de Montpellier, Montpellier 34293, FrancehThoracic Medicine, Gold Coast University Hospital, Southport, QLD 4125, AustraliaiSchool of Medicine and Dentistry, Griffith University, Southport, QLD 4032, Australia Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2537320123 https://www.pnas.org/doi/abs/10.1073/pnas.2537320123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2537490123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceHere, we identify histone acetyltransferase 1 (HAT1) as a lactyltransferase that catalyzes programmed cell death ligand 1 (PD-L1) lactylation, linking tumor metabolism to immune evasion. Mechanistically, HAT1-mediated lactylation stabilizes PD-... Lactylation of PD-L1 by a lactyltransferase HAT1 dictates its protein stability and tumor immune evasion doi:10.1073/pnas.2537490123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Man ShangXujie ZhaoYibi ZhangChang ZhangXiaohui YangYa WenXiaofeng ZhuYiwen ChenYinmin GuYongbo PanSiyuan JiangShuguang TanXuemei JiaChenbo JiShan Gaoahttps://ror.org/059gcgy73Department of Gynecology, Women’s Hospital of Nanjing Medical University (Nanjing Women and Children’s Healthcare Hospital), Nanjing 210004, ChinabZhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Southeast University, Nanjing 210096, ChinacNanjing Medical Key Laboratory of Female Fertility Preservation and Restoration, Nanjing 210004, Chinadhttps://ror.org/02wmsc916Medical College, Guizhou University, Guiyang 550025, Chinaehttps://ror.org/00a2xv884Innovative Vaccine and Immunotherapy Research Center, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Chinafhttps://ror.org/059gcgy73State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Women and Children’s Healthcare Institute, Biobank, and Cell Therapy Center, Women’s Hospital of Nanjing Medical University, (Nanjing Women and Children’s Healthcare Hospital), Nanjing 210004, ChinagJiangsu Provincial Engineering Research Center of Cancer Cell Therapy and Translational Medicine, Xuzhou Central Hospital, Southeast University, Xuzhou 221000, China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2537490123 https://www.pnas.org/doi/abs/10.1073/pnas.2537490123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2608405123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceAngle-independent structural colors from disordered colloids could replace conventional pigments, but “true red” has remained elusive, because blue light scattered by individual particles washes out the color. We design a photonic glass paint ... Metallodielectric photonic glass paints enable hyperchromatic, angle-independent structural color across the full visible spectrum doi:10.1073/pnas.2608405123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Yuwon JeonJaewon LeeYongDeok ChoMinyoung ParkKyeongsoo KimSoyul KwakSeungwoo LeeaKorea University-Korea Institute of Science and Technology (KU-KIST) Graduate School of Converging Science and Technology, Korea University, Seoul 02841, Republic of KoreabDepartment of Biomicrosystem Technology, Korea University, Seoul 02841, Republic of KoreacDepartment of Integrative Energy Engineering, Korea University, Seoul 02841, Republic of KoreadCenter for Opto-Electronic Materials and Devices, Post-Silicon Semiconductor Institute, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2608405123 https://www.pnas.org/doi/abs/10.1073/pnas.2608405123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2601546123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceMotor learning is often studied in specific brain regions, yet how the whole brain reconfigures during adaptation remains unknown. Using a trajectory analysis of human functional magnetic resonance imaging (fMRI) data, we show global ... Dynamic compression of whole-brain neural trajectories during human motor learning doi:10.1073/pnas.2601546123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Hoora MohseniAli RezaeiMaryam Ansari EsfehCorson N. AreshenkoffDaniel J. GaleJoseph Y. NashedEmily R. ObyJuan ChenJeffrey D. WammesDouglas J. CookJason P. GallivanaCenter for Neuroscience Studies, Queen’s University, Kingston, ON K7L 3N6, CanadabDepartment of Psychology, Queen’s University, Kingston, ON K7L 3N6, CanadacDepartment of Biomedical and Molecular Sciences, Queen’s University, Kingston, ON K7L 3N6, CanadadKey Laboratory of Brain, Cognition and Education Sciences (South China Normal University), Ministry of Education, Guangzhou, Guangdong Province 510631, ChinaeCenter for the Study of Applied Psychology, Guangdong Key Laboratory of Mental Health and Cognitive Science, and the School of Psychology, South China Normal University, Guangzhou, Guangdong Province 510631, ChinafPhilosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Ministry of Education, Guangdong Province 510631, ChinagSchool of Medicine, Queen’s University, Kingston, ON K7L 3N6, CanadahDivision of Neurosurgery, Department of Surgery, Queen’s University, Kingston, ON K7L 3N6, Canada Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2601546123 https://www.pnas.org/doi/abs/10.1073/pnas.2601546123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2604717123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceCurrent atmospheric models indicate that aerosols generally have an acidic surface. This study challenges that paradigm by revealing the existence of an “alkaline shell” (pH ~ 11) on organic-coated microdroplet aerosols. We show that this ... Interfacial electric fields create hyperalkaline shells on fatty acid–coated microdroplet aerosols doi:10.1073/pnas.2604717123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Yangyang LiuSonali SrivastavaDelicia GonsalvesPeter J. VikeslandaDepartment of Civil and Environmental Engineering, Virginia Tech, Blacksburg, VA 24061bVirginia Tech Institute of Critical Technology and Applied Science, Virginia Tech Sustainable Nanotechnology Center (VTSun), Blacksburg, VA 24061 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2604717123 https://www.pnas.org/doi/abs/10.1073/pnas.2604717123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2519139123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceUrinary tract infections (UTIs) are among the most common bacterial infections. Their initiation depends on the ability of uropathogenicEscherichia coli(UPEC) to adhere to bladder cells. Adhesion is mediated by FimH, a two-domain protein on ... Ultraslow conformational dynamics and catch bond formation of a bacterial adhesin revealed by a single-domain variant of FimH doi:10.1073/pnas.2519139123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Pearl MagalaLisa M. TuttleGianluca InterlandiLaura A. CarlucciMolly Y. MollicaMaria K. JanowskaWendy E. ThomasEvgeni V. SokurenkoRachel E. Klevitahttps://ror.org/00cvxb145Department of Biochemistry, University of Washington, Seattle, WA 98195bhttps://ror.org/00cvxb145Department of Bioengineering, University of Washington, Seattle, WA 98195chttps://ror.org/00cvxb145Department of Microbiology, University of Washington, Seattle, WA 98195 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2519139123 https://www.pnas.org/doi/abs/10.1073/pnas.2519139123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2520003123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceCysts are fluid-filled cavities surrounded by a cellular monolayer. Interactions between cysts are important during morphogenesis, yet their governing rules are poorly understood. Here, we designed a doublet assay using microfabrication to ... Interaction dynamics between epithelial cysts captured by tissue rheology doi:10.1073/pnas.2520003123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Marie AndréLinjie LuMichèle LiebDavid Gonzalez-RodriguezDaniel Rivelineahttps://ror.org/0015ws592Université de Strasbourg, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), UMR 7104- UMR-S 1258, Illkirch F-67400, Francebhttps://ror.org/0015ws592CNRS, UMR 7104, CNRS, Illkirch F-67400, FrancecINSERM, UMR-S 1258, Illkirch F-67400, Francedhttps://ror.org/0015ws592Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Development and Stem Cells Department, Illkirch F-67400, Franceehttps://ror.org/04vfs2w97Université de Lorraine, Laboratoire de Chimie et Physique - Approche Multi-échelles des Milieux Complexes (LCP-A2MC), Metz F-57000, France Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2520003123 https://www.pnas.org/doi/abs/10.1073/pnas.2520003123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2536452123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceSocial status, such as popularity, profoundly shapes our lives, yet how it emerges from individuals’ hidden mental processes is poorly understood. We combine neuroimaging with longitudinal school-wide social network analysis to track ... Early neural attunement to peer status predicts future social network position and popularity in adolescents doi:10.1073/pnas.2536452123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Won-Gyo ShinKiho SungJunho BangSunhae SulYoosik YoumCarolyn ParkinsonaDepartment of Sociology and Laboratory of Social Networks and Neuroscience, Yonsei University, Seoul 03722, Republic of KoreabDepartment of Psychology, Pusan National University, Busan 46241, Republic of KoreacDepartment of Data Science, Hanyang University, Seoul 04763, Republic of KoreadDepartment of Psychology, University of California, Los Angeles, CA 90095 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2536452123 https://www.pnas.org/doi/abs/10.1073/pnas.2536452123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2531265123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceThe CRISPR/Cas9-based mosaic technique, mosaic analysis by gRNA-induced crossing-over (MAGIC), is a versatile tool for in vivo biological investigations. However, its reliance on DNA double-strand breaks can cause significant, unintended cell ... Tuning mitotic recombination with patterned DNA nicks for precision mosaic analysis doi:10.1073/pnas.2531265123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Yifan ShenAnn T. YeungBei WangChun-Ting YehPayton DitchfieldElizabeth KornChun HanaDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853bWeill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2531265123 https://www.pnas.org/doi/abs/10.1073/pnas.2531265123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2535878123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceEnergy homeostasis depends on precise coordination between hypothalamic outputs and peripheral metabolic tissues. The ventromedial hypothalamus (VMH) is central to this regulation, yet the pathways linking it to distinct adipose depots remain ... Projection-defined hypothalamic outputs differentially regulate thermogenesis and lipolysis doi:10.1073/pnas.2535878123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Hyeonyoung MinQi ZhengYunlei Yangahttps://ror.org/05cf8a891Department of Medicine Division of Endocrinology, Albert Einstein College of Medicine, Bronx, NY 10461bhttps://ror.org/05cf8a891Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461chttps://ror.org/05cf8a891Einstein-Mount Sinai Diabetes Research Center, Albert Einstein College of Medicine, Bronx, NY 10461dhttps://ror.org/05cf8a891The Fleischer Institute for Diabetes and Metabolism, Albert Einstein College of Medicine, Bronx, NY 10461 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2535878123 https://www.pnas.org/doi/abs/10.1073/pnas.2535878123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2602234123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceSince the discovery of superconductivity in twisted bilayer graphene in 2018, moiré superlattices have emerged as an important platform for controlling electronic states in two-dimensional (2D) materials. Despite this impact, the construction ... Strain-induced deterministic moiré superlattices in 2D materials doi:10.1073/pnas.2602234123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Yu-Mi WuSihun LeeYufeng XiStephen D. FunniSaif SiddiqueNatalie L. WilliamsGiovanni SartorelloHesam AskariJudy J. Chaahttps://ror.org/05bnh6r87Department of Materials Science and Engineering, Cornell University, Ithaca, NY 14853bhttps://ror.org/022kthw22Department of Mechanical Engineering, University of Rochester, Rochester, NY 14611chttps://ror.org/05bnh6r87Kavli Institute at Cornell for Nanoscale Science, Cornell University, Ithaca, NY 14853dhttps://ror.org/05bnh6r87Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853ehttps://ror.org/05bnh6r87Cornell NanoScale Science and Technology Facility, Cornell University, Ithaca, NY 14853 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2602234123 https://www.pnas.org/doi/abs/10.1073/pnas.2602234123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2603937123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceAchieving the goal of “Zero Hunger” is an urgent global priority, given the profound impact of micronutrient deficiencies on human health and economic development. This study employed multiplex gene editing technology to target five key genes ... Multiplex gene editing enables the multibiofortification of essential vitamins and other health-promoting phytonutrients in tomato doi:10.1073/pnas.2603937123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Yechun HongZongjun YuWenbo ZhuJialei SunZeyao ZhuZhen WangMinjie CaoZhaobo LangYu-Xuan LyuPengpeng LiuJian-Kang ZhuaInstitute of Advanced Biotechnology, Institute of Homeostatic Medicine, and School of Medicine, Southern University of Science and Technology, Shenzhen 518055, ChinabSchool of Life Sciences, Anhui Agricultural University, Hefei, Anhui 230036, ChinacFaculty of Medicine, Macau University of Science and Technology, Macau SAR 999078, China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2603937123 https://www.pnas.org/doi/abs/10.1073/pnas.2603937123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2535319123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceThe RAS-GTPase activating protein (RAS-GAP) related domain of neurofibromin constitutes a small portion of the protein, suggesting that neurofibromin may possess additional functions beyond its well-characterized role in RAS regulation. In ... NF1 and SPRED1/2 cooperate through RAS-MAPK-independent functions doi:10.1073/pnas.2535319123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Jillian M. SilvaLizzeth CancheAlice ChengLucy C. YoungFrank McCormickahttps://ror.org/043mz5j54Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94153 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2535319123 https://www.pnas.org/doi/abs/10.1073/pnas.2535319123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2600749123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificancePlant interactions shift from facilitation to competition with increasing neighbor densities, but whether functional traits predict this transition remains unclear. We show that basic dimensions of functional traits, such as flower size and ... Trait-mediated interactions drive local diversity doi:10.1073/pnas.2600749123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Lisa BucheOscar GodoyLauren G. ShoemakerPeter VeskLauren M. HallettCourtney G. TaylorWing Man SiuManuel SevenelloMargaret M. MayfieldaSchool of Biosciences, University of Melbourne, Melbourne, VIC 3010, AustraliabEstación Biológica de Doñana, Sevilla 41092, SpaincDepartment of Botany, University of Wyoming, Laramie, WY 82071dSchool of Agriculture, Food and Ecosystem Sciences, University of Melbourne, Melbourne, VIC 3010, AustraliaeBiology Department and Environmental Studies Program, University of Oregon, Eugene, OR 97403 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2600749123 https://www.pnas.org/doi/abs/10.1073/pnas.2600749123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2604770123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceDysregulation ofhsART1 activity has been shown to permit immune cell evasion in non–small cell lung cancer through elevated mono-ADP ribosylation (MARylation) at Arg125 of purinergic type 2 receptor (P2X7) in P2X7-positive T cells, resulting ... Transition-state analysis of the arginine-specific human ADP-ribosyltransferase 1 doi:10.1073/pnas.2604770123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Daniel P. GroomJennifer T. AguilanAmanda LopacinskiScott J. GarforthVern L. Schrammahttps://ror.org/05cf8a891Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461bhttps://ror.org/05cf8a891Department of Pathology, Albert Einstein College of Medicine, Bronx, NY 10461 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2604770123 https://www.pnas.org/doi/abs/10.1073/pnas.2604770123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2507074123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceThis work constructs a high-resolution, multilayered spatiotemporal representation of the contiguous U.S., integrating livestock populations, processing centers, wild bird abundances, and human demographics using diverse datasets and advanced ... A high-resolution, US-scale digital similar of interacting livestock, wild birds, and human ecosystems for multihost epidemic spread doi:10.1073/pnas.2507074123 Proceedings of the National Academy of Sciences 2026-05-28T07:00:00Z Abhijin AdigaAyush ChopraMandy L. WilsonS. S. RaviDawen XieSamarth SwarupBryan L. LewisAndrew Scott WarrenJohn BarnesRamesh RaskarMadhav V. Maratheahttps://ror.org/0153tk833Biocomplexity Institute, University of Virginia, Charlottesville, VA 22904bhttps://ror.org/042nb2s44Massachusetts Institute of Technology Media Lab, Massachusetts Institute of Technology, Cambridge, MA 02139cOffice of Advanced Molecular Detection, U.S. Centers for Disease Control, Atlanta, GA 30333dhttps://ror.org/0153tk833Department of Computer Science, University of Virginia, Charlottesville, VA 22904 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2507074123 https://www.pnas.org/doi/abs/10.1073/pnas.2507074123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2533286123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceExcessive intestinal lipid absorption is a key driver of obesity, yet how gut microbes regulate this process remains unclear. Here we identify a previously unrecognized gut microbiota–Fatty acid binding protein 1 (FABP1) regulatory axis ... Akkermansia muciniphila–derived L-norleucine modulates FABP1-dependent fatty acid transport doi:10.1073/pnas.2533286123 Proceedings of the National Academy of Sciences 2026-05-28T07:00:00Z Juan LiZhengcai MaJinyin ZhangChunyong SunHuimin WuXiaoduo LiZheng LiHuiqing WangYubin YangLianchun ShangZhipeng YangJianyu ZhuJifei LiuRakia ManzoorLi TangXuegang LiXiaoli YeHang MaaEngineering Research Center of Coptis Development and Utilization (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, Chinabhttps://ror.org/00pcrz470School of Modern Chinese Medicine Industry, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, Chinachttps://ror.org/01kj4z117School of Life Sciences, Southwest University, Chongqing 400715, ChinadFaculty of Chemistry and Life Sciences, Gansu Minzu Normal University, Hezuo 747000, ChinaeDepartment of Clinical Laboratory, AnShun City People’s Hospital, Guizhou 561000, Chinafhttps://ror.org/02vg7mz57School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, People’s Republic of Chinaghttps://ror.org/011ashp19West China Second Hospital, Sichuan University, Chengdu 610041, ChinahKey Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu 610041, Chinaihttps://ror.org/02axars19Emergency Department, Chongqing Hospital Affiliated to Jiangsu Provincial Hospital of Chinese Medicine, Chongqing 402160, Chinajhttps://ror.org/04qzpec27College of Health Science and Environmental Engineering, Shenzhen Technology University, Shenzhen 518118, China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2533286123 https://www.pnas.org/doi/abs/10.1073/pnas.2533286123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2535708123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceFilamentous entanglement underlies the resilience and toughness of systems from polymer networks to textiles, yet most architected materials do not capitalize on this principle. While knitting research across mechanics, architecture, and ... Entanglement-driven responses through multiscale 3D-printed knits doi:10.1073/pnas.2535708123 Proceedings of the National Academy of Sciences 2026-05-28T07:00:00Z Bradley ClineCatherine BaiSehui JeongLing XuYue WangJames U. SurjadiCarlos M. PortelaTian ChenaDepartment of Mechanical and Aerospace Engineering, University of Houston, Houston, TX 77002bDepartment of Mechanical Engineering, Stanford University, Stanford, CA 94305cDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139dDepartment of Aeronautics, Imperial College London, London SW7 2AZ, United Kingdom Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2535708123 https://www.pnas.org/doi/abs/10.1073/pnas.2535708123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2533675123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceNatural convection in porous and fractured materials governs heat transport in systems ranging from planetary hydrothermal circulation to engineered thermal technologies. Because the structure of these materials is often unknown, their flows ... Dynamic confinement controls the porous-to-free convection transition doi:10.1073/pnas.2533675123 Proceedings of the National Academy of Sciences 2026-05-28T07:00:00Z Dario M. SchwendenerJerome NoirJonas LattChristophe CoreixasXiang-Zhao Kongahttps://ror.org/05a28rw58Department of Earth and Planetary Sciences, Institute of Geophysics, Geothermal Energy and Geofluids Group, ETH Zürich, Zurich 8092, Switzerlandbhttps://ror.org/05a28rw58Department of Earth and Planetary Sciences, Institute of Geophysics, Earth and Planetary Magnetism, Institute of Geophysics, ETH Zürich, Zurich 8092, Switzerlandchttps://ror.org/01swzsf04Department of Computer Science, University of Geneva, Carouge 1227, Switzerlanddhttps://ror.org/04snvc712Institute for Advanced Study, Beijing Normal–Hong Kong Baptist University, Zhuhai 519087, China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2533675123 https://www.pnas.org/doi/abs/10.1073/pnas.2533675123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2609796123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceStructural maintenance of chromosomes complexes such as cohesin and condensin actively organize genomes by extruding DNA loops. A key property of these motors is their processivity–the distance and duration over which loop extrusion persists. ... Theory of chromosome structural dynamics by processive loop extrusion doi:10.1073/pnas.2609796123 Proceedings of the National Academy of Sciences 2026-05-28T07:00:00Z Zhiyu CaoChaoqun DuZhonghuai HouPeter G. WolynesaCenter for Theoretical Biological Physics, Rice University, Houston, TX 77005bDepartment of Chemical Physics, University of Science and Technology of China, Hefei, Anhui 230026, ChinacDepartment of Chemistry, Rice University, Houston, TX 77005dDepartment of Physics, Rice University, Houston, TX 77005 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2609796123 https://www.pnas.org/doi/abs/10.1073/pnas.2609796123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2600483123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificancePredicting the genetic consequences of population decline is a major problem in conservation genomics. The black abalone was a culturally and economically important North American mollusk that declined by ~99% in the 1980s due to a rapid ... Ancient DNA from shells reveals delayed genomic erosion and rapid immune adaptation in the critically endangered black abalone doi:10.1073/pnas.2600483123 Proceedings of the National Academy of Sciences 2026-05-28T07:00:00Z T. Brock WooldridgeJoshua D. KappSarah M. FordWilliam E. SeligmannHolland C. ConwellTalia TzadikarioJonas OppenheimerZachary G. AndersonAlan Le MoanAlicia Abadía-CardosoPeter RaimondiBeth Shapiroahttps://ror.org/03s65by71Department of Ecology and Evolutionary Biology, University of California, Santa Cruz, CA 95060bhttps://ror.org/03s65by71Department of Biomolecular Engineering, University of California, Santa Cruz, CA 95060cCollege of Science, Northeastern University, Boston, MA 02215dhttps://ror.org/02en5vm52Laboratoire de Biologie Intégrative des Modèles Marins, Sorbonne Université, CNRS, Roscoff F-29680, Franceehttps://ror.org/05xwcq167Facultad de Ciencias Marinas, Universidad Autónoma de Baja California, Pedregal Playitas, Ensenada 22860, Baja California, MexicofColossal Biosciences, Austin, TX 75247 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2600483123 https://www.pnas.org/doi/abs/10.1073/pnas.2600483123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2524747123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceVerifying results of published social sciences research is essential but expensive, costing hundreds of dollars per study. With AI tools like ChatGPT becoming widespread, we tested whether they could help scientists check if research findings ... AI-assisted teams outperform AI-led teams but not human-only teams in assessing research reproducibility in quantitative social science doi:10.1073/pnas.2524747123 Proceedings of the National Academy of Sciences 2026-05-28T07:00:00Z Abel BrodeurDavid ValentaAlexandru MarcociJuan P. AparicioDerek MikolaBruno BarbarioliRohan AlexanderLachlan DeerTom StaffordLars VilhuberGunther BenschFabio MotokiMohamed AbdelhadyYousra AbdelmoulaGhina Abdul BakiTomás AguirreSriraj AiyerShumi AkhtarFarida AkhtarMelle R. AlbadaMicah AltmanDavid AngenendtZahra Arjmandi LariJorge Armando De León TejadaDavid Rodriguez AranaIgor AsanovAnastasiya-Mariya NohaRebecca AshongTobias AuerFrancisco J. Bahamonde-BirkeBradley J. BakerSöhnke M. BartramDongqi BaoLucija BatinovicTommaso BatistoniMonica BeederLouis-Philippe BelandCarsten Gero BienzChrist Billy AryantoCylcia BolibaughCarl BonanderRamiro BravoEgor BronnikovStephan BrunsNino BuliskeriaSara Caicedo-SilvaAndrea CalefJuan Sebastian Cano AriasGustavo A. Castillo AlvarezSolomon CaulkerSimonas CepenasArthur ChattonZirou ChenNgozi Chioma EwurumAnda-Bianca CiocîrlanFelix J. ClouthJason CollinsNikolai CookCesar CornejoJoão CraveiroJonathan CréchetJing CuiNiveditha Chalil VayalabronChristian CzymaraCarlos Daniel Bermúdez JaramilloHannes DattaLien DenooArshia DhaliwalNency DhamejaElodie DjemaiErwan DujeancourtUǧurcan DündarThibaut DupreyYasmine EissaYoussef El FassiIsmail El FassiKeaton EllisAli ElminejadMahmoud ElsherifAysil EmirmahmutogluGiulian Etingin-FratiEmeka EzeJan Fabian DollbaumJan FeldAndres Felipe Rengifo JaramilloGuidon FenigVictoria FernandesLenka FialaLukas FinkMojtaba FirouzjaeiangalougahSara FishJack FitzgeraldRachel ForshawAlexandre Fortier-ChouinardLouis FrégetJoris FreseJacopo GabaniSebastian GallegosMax C. GamillAttila GáspárRomain GauriotEvelina GavrilovaDiogo GeraldesGiulio Giacomo CantoneGrant GibsonDirk GoldschmittAmélie Gourdon-KanhukamweAndrea Gregor de VardaIdaliya GrigoryevaAlexi GugushviliAaron H. A. FletcherFlorian HabermannMárton HablicsekJoanne HaddadJonathan D. HallOlle HammarMalek HassounehCarina I. HausladenSophie C. F. HendrikseMatthew HepplewhiteAnson T. Y. HoSenan Hogan-HennessyElliot HowleyGaoyang HuangHéloïse HulstaertZlatomira G. IlchovskaPaola Jaimes SantamariaNiklas JakobssonJoakim JanssonEwa JaroszHossein JebeliYanchen JiangHiba JunaidRohan KallurayaSunny KarimEdmund KellyEva KimelSorravich KingsuwankulValentin KlotzbücherDaniel KrähmerPijus KrūminasNicholas KruusEssi KujansuuChristoph F. KurzStephan KüsterBlake Lee-WhitingFelix LewandowskiTongzhe LiRuoxi LiDan LiuJiacheng LiuHelix LoKatharina LoterFelipe Macedo DiasChristopher R. MadanNicolas MäderMarco MandasCesar MantillaJan MarcusDiego Marino FagesXavier MartinRyan McWayDaniel Medina-GasparSisi MengLingyu MengSimon MerzAlex P. MillerThibault MirabelDibya Deepta MishraSumit MishraBelay W. MogesMorteza Mohandes MojarradMyra MohnenLouis-Philippe MorinLucija MuehlenbachsGastón MullinAndreea MusulanSara MuzzìJames A. C. MyersFlorian NeubauerTuan NguyenAli NiaziArdyn NordstromBartłomiej NowakDaneal O’HabibTim ÖlkersJustin OngValeria Orozco CastiblancoÖmer ÖzakAli I. OzkesMikael PaasoShubham PandeyVarvara PapazoglouRomeo PenheiroLinh PhamUlrike PhielerPeter PützQuan QiJingyi QiuManuel T. ReinDavid A. ReinsteinJuuso RepoNicolas RudolfShree SahaOrkun SakaChiara SaponaroGeorg SatorMartijn SchoenmakersRaffaello SeriMeet ShahPaul SibilleChristoph SiemrothVladimir SkavyshBen SlaterWenting SongStefan StaubliTobias SteindlNomwendé Steven WaongoPaul StottStephenson StrobelRoshini SudhaharanPu SunScott D. SwainOleksandr TalaveraHanz M. TantiangcoGeorgy TarasenkoBoyd TarlintonMariam TarrafKen TeohRémi ThériaultBethan ThompsonTonghui TianWenjie TianEmmanuel TolaniNicolai BorgenSolveig Topstad BorgenJavier TorralbaCarolina Velez-OspinaMan Wai MakLukas WallrichZeyang WangLeah WardMatthew D. WebbDuncan WebbBryan S. WeberChristoph WeberWei-Chien WengChristian WestheideTom WilkinsonKwong-Yu WongMarcin WrońskiZhuangchen WuQixia WuVictor Y. WuBohan XiaoFeihong XuCong XuPranav YadavYu Yang ChouLuther YapMyra YazbeckBo YaoZuzanna ZagrodzkaTahreen ZahraMirela ZanevaXiaomeng ZhangZiwei ZhaoHan ZhongAras ZirgulisJiacheng ZouFloris ZoutmanChristelle ZozoungboaDepartment of Economics, Faculty of Social Sciences, University of Ottawa, Ottawa, ON K1N 6N5, CanadabInstitute for Replication, Ottawa, ON K1N 6N5, CanadacInstitute for Technology and Humanity, University of Cambridge, Cambridge CB2 1SB, United KingdomdDepartment of Statistical Sciences, Faculty of Information, University of Toronto, Toronto, ON M5S 3G6, CanadaeDepartment of Management and Marketing, University of Melbourne, Melbourne, Carlton, VIC 3010, AustraliafSchool of Psychology, University of Sheffield, Sheffield S1 4DP, United KingdomgResearch on Research Institute, London WC1E 6JA, United KingdomhDepartment of Economics, Cornell University, Ithaca, NY 14853iClimate and Development Policy Division, Leibniz Institute for Economic Research - Leibniz Institute for Economic Research, Essen, NRW 45128, GermanyjRobert C. Vackar College of Business and Entrepreneurship, University of Texas Rio Grande Valley, Edinburg, TX 78539kNorwich Business School, Accounting and Quantitative Methods, University of East Anglia, Norwich NR4 7TJ, United KingdomlDepartment of Economics, Carleton University, Ottawa, ON K1S 5B6, CanadamStatistics Canada, Ottawa, ON K1A 0T6, CanadanGovAI, N1 9JY, London, United KingdomoDepartment of Experimental Psychology, University of Oxford, Oxfordshire OX1 3EL, United KingdompFinance Discipline, University of Sydney Business School, The University of Sydney, Sydney, NSW 2006, AustraliaqDepartment of Actuarial Studies and Business Analytics, Macquarie Business School, Macquarie University, Sydney, NSW 2019, AustraliarDepartment of Socioeconomics, Vienna University of Economics and Business, Vienna 1020, AustriasCenter for Research on Equitable and Open Scholarship, Massachusetts Institute of Technology, Cabmridge, MA 02139tTechnical University of Munich School of Management, Technical University of Munich, Munich 80333, GermanyuCentre for Business Research, University of Cambridge, Cambridge CB2 1QA, United KingdomvIndependent researcher, Shiraz, IranwFacultad de Economía, Universidad del Rosario, Bogotá 111711, ColombiaxSchool of Economics, Universidad del Rosario, Bogotá 111711, ColombiayInternational Center for Higher Education Research and Faculty of Economics, University of Kassel, Kassel, Hessen 34125, GermanyzDepartment of Economics, University of Ghana, Legon, Accra, GhanaaaDepartment of Economics, University of Basel, Basel 4052, SwitzerlandbbDepartment of Methodology and Statistics, Tilburg School of Social and Behavioral Sciences, Tilburg University, Tilburg 5037 AB, The NetherlandsccDepartment of Sport, Tourism and Hospitality Management, Temple University, Philadelphia, PA 19312ddWarwick Business School, University of Warwick, Coventry CV4 7AL, United KingdomeeCenter for Economic Policy Research, Coldbath Square, London EC1R 5HL, United KingdomffDepartment of Economics, University of Zurich, Zurich CH-8001, SwitzerlandggDepartment of Behavioural Sciences and Learning, Linköping University, Linköping 58183, SwedenhhCentre for Experimental Social Sciences, Nuffield College, University of Oxford, Oxford OX1 1NF, United KingdomiiDepartment of Economics, University of Southampton, Southampton SO17 1BJ, United KingdomjjDepartment of Finance, Norwegian School of Economics, Bergen 5045, NorwaykkFaculty of Psychology, Atma Jaya Catholic University of Indonesia, Jakarta 12930, IndonesiallDepartment of Education, University of York, York YO10 5DD, United KingdommmKarlstad Business School, Karlstad University, Karlstad SE-651 88, SwedennnCenter for Societal Risk Research, Karlstad University, Karlstad 65188, SwedenooFaculty of Biology Medicine and Health, The University of Manchester, Manchester M13 9NT, United KingdomppSchool of Business and Economics, Maastricht University, Maastricht 6211 LM, The NetherlandsqqDepartment of Political Science, University of Chicago, Chicago, IL 60637rrCentre for Environmental Sciences, Hasselt University, Hasselt 3500, BelgiumssInternational Center for Higher Education Research, University of Kassel, Kassel, Hessen 34125, GermanyttMeta-Research Innovation Center at Stanford, Stanford University, Stanford, CA 94305uuDepartment of Economics, Nazarbayev University, Astana 010000, KazaakhstanvvFacultad de Economía, Universidad de los Andes, Bogotá 111711, ColombiawwUniversity College London School of Management, University College London, London E14 5AA, United KingdomxxDepartment of Economics, Universidad de Los Andes, Bogotá 111711, ColombiayyUnited Methodist University Sierra Leone, Freetown, Sierra LeonezzDepartment of Economics, International School of Management University of Management and Economics, Vilnius LT-01103, LithuaniaaaaDépartement de Médecine Sociale et Préventive, Université Laval, Québec, QC G1V0A6, CanadabbbDépartement de Médecine Sociale et Préventive, Université de Montréal, Montréal, QC H3N1X9, CanadacccDepartment of Management, Marketing and Information Systems, Hong Kong Baptist University, Kowloon Tong, Hong Kong Special Administrative Regions of ChinadddDepartment of Economics, College of Management Sciences, Michael Okpara University of Agriculture, Umudike, Abia State 440109, NigeriaeeeBusiness School, University of Technology Sydney, Sydney, NSW 2007, AustraliafffDepartment of Economics, Wilfrid Laurier University, Waterloo, ON N2L 3C5, CanadagggDepartment of Medical Statistics, The London School of Hygiene & Tropical Medicine, London WC1E 7HT, United KingdomhhhDepartment of Computer Science, University College London, London WC1E 6BT, United KingdomiiiDepartment of Economics, Faculty of Social Sciences, University of Ottawa, Ottawa ON, CanadajjjBusiness School, Beijing Normal University, Beijing 100875, ChinakkkBeijing Normal University, Belt and Road School, Zhuhai, Guangdong 519085, ChinalllSchool of Earth and Planetary Science, National Institute of Science Education and Research, Odisha 752050, IndiammmMigration & Migrants, Netherlands Interdisciplinary Demographic Institute, The Hague NL-2511 CV, the NetherlandsnnnDepartment of Economics, Universidad del Rosario, Bogotá 111711, ColombiaoooDepartment of Marketing, Tilburg University, Tilburg 5000 LE, The NetherlandspppDepartment of Strategy & Entrepreneurship, Tilburg University, Tilburg 5000 LE, The NetherlandsqqqDepartment of Economics, Binghamton University, Binghamton, NY 13902rrrEconomics, Université Paris Dauphine-Paris Sciences et Lettres, Paris CEDEX 16 75775, FrancesssSwedish Institute for Social Research, Stockholm University, Stockholm 103 91, SwedentttDepartment of Economics and Statistics, Linnaeus University, Växjö 35195, SwedenuuuDepartment of Marketing, Vienna University of Economics and Business Vienna, Vienna 1020, AustriavvvFinancial Stability Department, Bank of Canada, Ottawa, ON K1A 0G9, CanadawwwOnsi Sawiris School of Business, The American University in Cairo, New Cairo 11835, EgyptxxxDepartment of Accounting and Control, Hautes études commerciales Lausanne, Lausanne 1015, SwitzerlandyyyInstitute for Accounting, Controlling and Auditing, University of St. Gallen, St. Gallen 9000, SwitzerlandzzzMonash University, Melbourne, VIC 3168, AustraliaaaaaSchool of Psychology and Vision Science, University of Leicester, Leicester LE1 7RH, United KingdombbbbPsychology, University of Birmingham, Birmingham B15 2TT, United KingdomccccDepartment of Business and Management Science, Norwegian School of Economics, Bergen 5045, NorwayddddKonjunkturforschungsstelle Swiss Economic Institute, ETH Zurich, Zurich 8092, SwitzerlandeeeeDepartment of Economics, College of Management Sciences, Michael Okpara University of Agriculture, Umudike 440109, Abia State, NigeriaffffSchool of Politics and International Relations, University College Dublin, Dublin 4, IrelandggggSchool of Economics and Finance, Victoria University of Wellington, Wellington 6011, New ZealandhhhhBusiness School, Universidad de los Andes, Bogota 111711, ColombiaiiiiUniversidad de los Andes, Bogota 111711, ColombiajjjjVancouver School of Economics, University of British Columbia, Vancouver, BC V6T 1Z4, CanadakkkkDepartment of Economics, Tilburg University, Tilburg, North Brabant 5037 AB, The NetherlandsllllDepartment of Economics, School of Business and Economics, Freie Universität Berlin, Berlin 14195, GermanymmmmDepartment of Business Management, Masaryk University, Brno 602 00, Czech RepublicnnnnSchool of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138ooooDepartment of Ethics, Governance, and Society, School of Business and Economics, Vrije Universiteit Amsterdam, Noord-Holland, Amsterdam 1081HV, The NetherlandsppppTinbergen Institute, Amsterdam, Noord-Holland 1018WB, The NetherlandsqqqqDepartment of Accountancy, Economics and Finance, Heriot-Watt University, Edinburgh EH14 4AS, United KingdomrrrrDepartment of Political Science, Université Laval, Québec, QC G1V0A6, Canadasssslaboratoire d’Économie de Dauphine, Centre Pour la Recherche EconoMique et ses Applications, Paris 75014, FrancettttDepartment of Political and Social Sciences, European University Institute, Fiesole 50014, ItalyuuuuHealth, Nutrition, and Population Global Practice, World Bank, Washington, DC 20433vvvvCentre for Health Economics, University of York, Heslington YO10 5DD, United KingdomwwwwBusiness School, Universidad Adolfo Ibañez, Santiago 7910000, ChilexxxxSchool of Chemical, Materials and Biological Engineering, University of Sheffield, Sheffield S1 3JD, United KingdomyyyyInstitute of Economics, Eötvös Loránd University Centre for Economic and Regional Studies, Budapest 1097, HungaryzzzzDepartment of Economics, Central European University, Vienna 1100, AustriaaaaaaDepartment of Economics, Deakin University, Burwood, VIC 3125, AustraliabbbbbSchool of Economics, University College Dublin, Dublin D04 F6X4, IrelandcccccCentre for Business and Economics Research, University of Coimbra, Coimbra 3000-145, PortugaldddddBehavioral Science, Geary Institute for Public Poliy, Dublin D04 P9C4, IrelandeeeeeDepartment of Law, Economics, and Sociology, “Magna Graecia” University of Catanzaro, Catanzaro 88100, ItalyfffffDepartment of Economics, McMaster University, Hamilton, ON L8S 4M4, CanadagggggThe Canadian Research Data Centre Network, Hamilton, ON L8S4M4, CanadahhhhhInstitute for Psychiatry, Psychology & Neuroscience, King’s College London, London SE5 9RJ, United KingdomiiiiiMcGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139jjjjjEconomics, University of California San Diego, La Jolla, California 92092kkkkkDepartment of Sociology and Human Geography, University of Oslo, Oslo N-0317, NorwaylllllSchool of Computer Science, University of Sheffield, Sheffield S1 4DP, United KingdommmmmmUniversity College Dublin Lochlann Quinn School of Business, University College Dublin, Dublin 4, IrelandnnnnnDepartment of Accounting and Control, University of Lausanne, Lausanne 1015, SwitzerlandoooooMathematics Institute, Leiden University, Leiden, South Holland 2333CA, The NetherlandspppppDepartment of Economics and Economic History, Unit of Economic Analysis, Universitat Autònoma de Barcelona, Bellaterra, Cerdanyola de Vallès 08193, SpainqqqqqDepartment of Economics, Finance, and Legal Studies, University of Alabama, Tuscaloosa, AL 35487rrrrrInstitute for Futures Studies, Stockholm 10131, SwedensssssDepartment of Economics, University of Toronto, Toronto, ON M5S 3G7, CanadatttttComputational Social Science, ETH Zürich, Zurich 8057, SwitzerlanduuuuuDepartment of Politics and International Relations, University of Oxford, Oxford OX1 3UQ, United KingdomvvvvvDepartment of Real Estate Management, Ted Rogers School of Management, Toronto Metropolitan University, Toronto, ON M5B 2K3, CanadawwwwwSchool of Psychology, University of Nottingham, Nottingham NG7 2RD, United KingdomxxxxxDepartment of Health Sciences and Technology, ETH Zurich, Zurich 8001, SwitzerlandyyyyyManagement School, HEC Liège, University of Liege, Liège 4000, BelgiumzzzzzDepartment of Psychology, University of York, York YO10 5DD, United KingdomaaaaaaSchool of Psychology, University of Birmingham, Birmingham B15 2SA, United KingdombbbbbbPolitical Economy Research Institute, University of Massachusetts Amherst, Amherst, MA 01003ccccccCenter for Economic and Policy Research, Washington, DC 20009ddddddResearch Institute of Industrial Economics, Stockholm 10215, SwedeneeeeeeFaculty of Economic Sciences, University of Warsaw, Warsaw 00-927, PolandffffffFinancial Stability Department, Climate Analysis Team, Bank of Canada, Ottawa, ON K1A 0G9, CanadaggggggBart’s Life Sciences, Bart’s Health National Health Services Trust, London E14 5HJ, United KingdomhhhhhhQueen Mary University of London, London E1 4NS, United KingdomiiiiiiSchool of Electrical and Computer Engineering, Cornell University, Ithaca, NY 14853jjjjjjCarleton University, Ottawa, ON K1S 5B6kkkkkkUniversity of Oxford, Oxford OX1 2JD, United KingdomllllllDepartment of Management and Organization, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, Noord-Holland 1081 HV, NetherlandsmmmmmmDepartment of Economics, University of Freiburg, Freiburg im Breisgau 79085, GermanynnnnnnDepartment of Clinical Research, University of Basel, Basel 4051, SwitzerlandooooooUniversity Hospital Basel, Basel 4031, SwitzerlandppppppDepartment of Sociology, Ludwig Maximilian University of Munich, Munich 80539, GermanyqqqqqqDepartment of Economics, Faculty of Economics and Statistics, University of Innsbruck, Innsbruck 6020, AustriarrrrrrDepartment of Economics, Turku School of Economics, University of Turku, Turku FI-20014, FinlandssssssDepartment of Health Economics, Ludwig-Maximilians-Universität Munich, Munich DE-80539, GermanyttttttSchool of Business and Economics, Freie Universität Berlin, Berlin 14195, GermanyuuuuuuDepartment of Political Science, University of Toronto, Toronto, ON M5S 3G5, CanadavvvvvvDepartment of Food, Agricultural and Resource Economics, University of Guelph, Guelph, ON N1G 2W1, CanadawwwwwwDepartment of Economics, Yale University, New Haven, CT 06520-8268xxxxxxResearch School of Economics, Australian National University, Canberra, ACT 2600, AustraliayyyyyySchool of Finance, Renmin University of China, Beijing 100872, ChinazzzzzzDepartment of Advanced Social and International Studies, University of Tokyo, Meguro City, Tokyo 153-8902, JapanaaaaaaaDyson School of Applied Economics and Management, Cornell University, Ithaca, NY 14850bbbbbbbDepartment of Economics, Knauss School of Business, University of San Diego, San Diego, CA 92110cccccccDepartment of Economics and Business Administration, University of Cagliari, Cagliari 09124, ItalydddddddDepartment of Economics, School of Administrative and Economic Sciences, Pontificia Universidad Javeriana, Bogotá 110231, ColombiaeeeeeeeDepartment of Economics, Durham University, Durham DH1 3LB, United KingdomfffffffSchool of Economics and Management, Tilburg University, Tilburg 5000 LE, The NetherlandsgggggggApplied Economics, University of Minnesota, Saint Paul, MN 55108hhhhhhhDepartment of Economics, School of Finance, Economics and Government, Universidad Escuela Finanzas Economía y Gobierno, Antioquia, Medellín 050022, ColombiaiiiiiiiSamuel Curtis Johnson School of Business, Cornell University, Ithaca, NY 14853jjjjjjjSchool of Economics, University of Sheffield, Sheffield S10 2TU, United KingdomkkkkkkkSchool of Economics and Business, University of Halle, Halle (Saale) 06108, GermanylllllllDepartment of Marketing, Marshall School of Business, University of Southern California, Los Angeles, CA 90089-1424mmmmmmmEqualis Capital, Paris 75116, FrancennnnnnnDepartment of Economics, Rice University, Houston, TX 77005oooooooInstitute for Financial Management and Research Graduate School of Business, Krea University, Sri City, Andhra Pradesh 517646, IndiapppppppDepartment of Psychology, Dilla University, Dilla, South Ethiopia 419, EthiopiaqqqqqqqCenter PhD Students, Research Group: Econometrics, Tilburg School of Economics and Management, Tilburg university, Tilburg 5037 AB, NetherlandsrrrrrrrDepartment of Economics, University of Ottawa, Ottawa, ON K1N 6N5, CanadasssssssDepartment of Economics, University of Calgary, Calgary, AB T2N 1N4, CanadatttttttResources for the Future, Washington, DC 20036uuuuuuuResearch Group: Econometrics, Tilburg School of Economics and Management, Tilburg University, Tilburg 5037 AB, The NetherlandsvvvvvvvDepartment of Political Science, University of Montreal, Montreal, QC H3T 1J4, CanadawwwwwwwInstitut de valorisation des données, Montreal, QC H3N 1V5, CanadaxxxxxxxDepartment of Medicine and Surgery, University of Milano-Bicocca, Milan 20126, ItalyyyyyyyyDepartment of Statistics and Quantitative Methods, University of Milano-Bicocca, Milan 20126, ItalyzzzzzzzDepartment of Health Sciences, University of York, York YO10 5DD, United KingdomaaaaaaaaClimate and Development Policy Division, RWI - Leibniz Institute for Economic Research, Berlin 10115, GermanybbbbbbbbSchool of Public Policy and Administration, Carleton University, Ottawa, ON K1S 5B6, CanadaccccccccInstitute of Psychology, Cardinal Stefan Wyszynski University, Warsaw 01-938, PolandddddddddCurrency Department, Bank of Canada, Ottawa, ON K1A 0G9, CanadaeeeeeeeeDepartment of Agricultural Economics and Rural Development, University of Göttingen, Göttingen, Niedersachsen 37083, GermanyffffffffInstituto de Estudios Superiores de la Empresa Business School, University of Navarra, Barcelona 08034, SpainggggggggUniversidad de Navarra, Pamplona 31009, SpainhhhhhhhhDepartment of Economics, Dedman College of Humanities and Sciences, Southern Methodist University, Dallas, TX 75275-0496iiiiiiiiSKEMA Business School, Groupe de Recherche en Droit, Économie et Gestion, Université Côte d’Azur, Lille 59777, FrancejjjjjjjjInstitute for Public Management and Governance, Vienna University of Economics and Business, Vienna 1020, AustriakkkkkkkkDepartment of Finance, Rotterdam School of Management, Erasmus University Rotterdam, Rotterdam, Zuid Holland 3012 CC, The NetherlandsllllllllInstitute of Psychology, Universität Osnabrück, Osnabrück 49078, GermanymmmmmmmmDepartment of Psychology, University of Houston, Houston, TX 77204nnnnnnnnDepartment of Economics, Business and Finance, Lake Forest College, Lake Forest, IL 60048ooooooooDepartment of Marketing, Vienna University of Economics and Business, Vienna 1020, AustriappppppppDepartment of Economics, Bielefeld University, Bielefeld 33615, GermanyqqqqqqqqDepartment of Economics, University at Albany, State University of New York, Albany, NY 12222rrrrrrrrSchool of Information, University of Michigan, Ann Arbor, MI 48109ssssssssThe Unjournal, Camden, DE 19934ttttttttFinnish Flagship Inequalities, Interventions, and New Welfare State Flagship Research Centre, University of Turku, Turku 20014, FinlanduuuuuuuuApplied Economics and Management, Cornell University, Ithaca, NY 14853vvvvvvvvDepartment of Economics, City St George’s, University of London, London EC1V 0HB, United KingdomwwwwwwwwDepartment of Psychology, University of Milano-Bicocca, Milan 20126, ItalyxxxxxxxxSchool of Economics, University of Nottingham, Nottingham NG7 2RD, United KingdomyyyyyyyyInsIDE Lab, Dipartimento di Economia, Università degli Studi dell’Insubria, Varese 21100, ItalyzzzzzzzzDepartment of Economics, University of Essex, Colchester CO4 3SQ, United KingdomaaaaaaaaaData and Digital Services Department, Bank of Canada, Ottawa, ON K1A 0G9, CanadabbbbbbbbbSystems and Computer Engineering Department, Carleton University, Ottawa, ON K1S 5B6, CanadacccccccccLeverhulme Centre for the Future of Intelligence, University of Cambridge, Cambridge CB2 1SB, United KingdomdddddddddDepartment of Economics, University of California, Davis, CA 95616eeeeeeeeeInstitute for Business Administration, University of Regensburg, Regensburg, Bavaria 93053, GermanyfffffffffDepartment of Linguistics, Ghent University, Gent 9000, BelgiumgggggggggDepartment of Linguistics and English Language, University of Manchester, Manchester M13 9PL, United KingdomhhhhhhhhhDepartment of Marketing, Tilburg School of Economics and Management, Tilburg University, Tilburg 5037 AB, The NetherlandsiiiiiiiiiSchool of Public Finance and Taxation, Dongbei University of Finance and Economics, Dalian 116025, ChinajjjjjjjjjDepartment of Marketing, Clemson University, Clemson, SC 29634kkkkkkkkkDepartment of Economics, University of Birmingham, Birmingham B15 2TT, United KingdomlllllllllSchool of Information, Journalism and Communication, University of Sheffield, Sheffield S10 2AH, United KingdommmmmmmmmmDepartment of Government, Cornell University, Ithaca, NY 14853nnnnnnnnnAgri-Science Queensland, Department of Primary Industries, Brisbane, QLD 4102, AustraliaoooooooooAsia and Pacific Department, International Monetary Fund, Washington, DC 20431pppppppppDepartment of Psychology, New York University, New York, NY 10003qqqqqqqqqSchool of Natural and Social Sciences, Scotland’s Rural College, Edinburgh EH9 3JG, United KingdomrrrrrrrrrChair of Agricultural Production and Resource Economics, Technical University of Munich, Freising 85354, GermanysssssssssThe Institute for Food and Resource Economics, University of Bonn, Bonn 53115, GermanytttttttttDepartment of Special Needs Education, Centre for Research on Equality in Education, University of Oslo, Oslo 0318, NorwayuuuuuuuuuWorld Bank, Washington, DC 20433vvvvvvvvvBirkbeck Business School, Birkbeck, University of London, London WC1E 7JL, United KingdomwwwwwwwwwDepartment of Economics, Vanderbilt University, Nashville, TN 37235-1819xxxxxxxxxDivision of Psychology & Mental Health, School of Health Sciences, University of Manchester, Manchester M13 9PL, United KingdomyyyyyyyyyCenter for Health and Wellbeing, Princeton University, Princeton, NJ 08544zzzzzzzzzDepartment of Economics, College of Staten Island, Staten Island, NY 10314aaaaaaaaaaCity University of New York, New York, NY 10017bbbbbbbbbbDepartment Economics, Law, and Society, Ecole upérieure des sciences commerciales School of Management, Angers 49003, FranceccccccccccDepartment of Economics, University of California, Davis, CA 95616ddddddddddStockholm Business School, Stockholm University, Stockholm 10691, SwedeneeeeeeeeeeLeibniz Institute for Financial Research Sustainable Architecture for Finance in Europe, Frankfurt, Hesse 60323, GermanyffffffffffDepartment of Economics, National University of Singapore, Singapore 117570, SingaporeggggggggggCollegium of World Economy, Szkoła Główna Handlowa Warsaw School of Economics, Warsaw 02-554, PolandhhhhhhhhhhDepartment of Political Science, Stanford University, Stanford, CA 94305iiiiiiiiiiDepartment of Engineering Sciences & Applied Mathematics, Northwestern University, Evanston, IL 60201jjjjjjjjjjReal Estate Economics, National Chengchi University, Taipei 11605, TaiwankkkkkkkkkkAalto University, Espoo 02150, FinlandllllllllllDepartment of Accounting, Tilburg School of Economics and Management, Tilburg University, Tilburg 5037 AB, The NetherlandsmmmmmmmmmmDepartment of Economics, Faculty of Arts and Social Sciences, National University of Singapore, Singapore 117570, SingaporennnnnnnnnnSchool of Economics, Faculty of Buisness Economics and Law, University of Queensland, Brisbane, St Lucia, QLD 4072, AustraliaooooooooooDepartment of Psychology, Faculty of Science and Technology, Fylde College, Lancaster University, Lancaster LA1 4YF, United KingdomppppppppppSchool of Biosciences, University of Sheffield, Sheffield S10 2TN, United KingdomqqqqqqqqqqChrist Church College, University of Oxford, Oxfordshire OX1 1DP, United KingdomrrrrrrrrrrEconomics Experimental Lab, Nanjing Audit University, Nanjing 210017, ChinassssssssssDepartment of Finance, HEC, University of Lausanne, Lausanne 1015, SwitzerlandttttttttttSwiss Finance Institute, Lausanne 1015, SwitzerlanduuuuuuuuuuDepartment of Marketing, Rotman School of Management, University of Toronto, Toronto, ON M5S 1A1, CanadavvvvvvvvvvDepartment of Industrial Engineering and Operations Research, Columbia University, New York, NY 10027wwwwwwwwwwDepartment of Economics, Penn State University, University Park, PA 16802 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2524747123 https://www.pnas.org/doi/abs/10.1073/pnas.2524747123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2602255123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceSeveral factors, such as droughts and pathogens, can compromise our ability to produce food under current monoculture industrial agriculture. Here, we analyze data from a long-term managed grassland studied in the Park Grass Experiment (... Toward systems agroecology: Risk–reward balance, emergent plant communities, and temporal weather map in multiplant farming doi:10.1073/pnas.2602255123 Proceedings of the National Academy of Sciences 2026-05-28T07:00:00Z Sirio Belga FedeliStanislas LeibleraSimons Center for Systems Biology, School of Natural Sciences, Institute for Advanced Study, Princeton, NJ 08540bLaboratory of Living Matter, The Rockefeller University, New York, NY 10065 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2602255123 https://www.pnas.org/doi/abs/10.1073/pnas.2602255123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2527106123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceAdministrative costs have ballooned across industries—raising tuition, healthcare expenses, and employee burnout. Why does this burden persist, and how can it be reversed? We develop a dynamic model showing how well-intentioned problem-solving ... What leads to administrative bloat? A dynamic model of administrative cost and waste doi:10.1073/pnas.2527106123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z Vicky Chuqiao YangLevi Grenierahttps://ror.org/042nb2s44MIT Sloan School of Management, Massachusetts Institute of Technology, Cambridge, MA 02139bhttps://ror.org/042nb2s44Institute for Data, Systems, and Society, Massachusetts Institute of Technology, Cambridge, MA 02139 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2527106123 https://www.pnas.org/doi/abs/10.1073/pnas.2527106123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2536082123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceHuman cytomegalovirus (HCMV) establishes lifelong infection by toggling between latent and lytic states. Yet, the factors that determine this decision are not fully understood. Here, we show that the abundance of the immediate-early proteins ... Parsing the functions of immediate-early proteins in the lytic–latent balance of HCMV infection doi:10.1073/pnas.2536082123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z Yaarit KitsbergAharon NachshonAlexander BrandisTevie MehlmanNoam Stern-GinossarMichal Schwartzahttps://ror.org/0316ej306Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israelbhttps://ror.org/0316ej306Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot 7610001, Israel Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2536082123 https://www.pnas.org/doi/abs/10.1073/pnas.2536082123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2534673123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceLiver fibrosis is fundamentally driven by the activation of hepatic stellate cells (HSCs), wherein activated HSCs characterized by elevated fibroblast activation protein (FAP) expression serve as pivotal pathogenic effectors promoting ... mRNA-laden LNP-enabled in situ CAR-macrophage alleviates liver fibrosis via inhibiting activated HSCs and modulating the immune microenvironment doi:10.1073/pnas.2534673123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z Xin HuangJunfeng HaoShuo WangBotian DengPeng WangQiuyu ZhaoHongbo LiuJiahe WangaDepartment of Family Medicine, Shengjing Hospital of China Medical University, Shenyang 110022, Chinabhttps://ror.org/04k5rxe29Department of Nephrology, and Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-communicable Diseases, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, ChinacDepartment of Cardiology, Shengjing Hospital of China Medical University, Shenyang 110022, Chinadhttps://ror.org/030e3n504Department of Key Laboratory of Ministry of Education for Traditional Chinese Medicine Viscera-State Theory and Applications, Liaoning University of Traditional Chinese Medicine, Shenyang 110847, ChinaeThird Department of Respiratory, Shengjing Hospital of China Medical University, Shenyang 110022, China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2534673123 https://www.pnas.org/doi/abs/10.1073/pnas.2534673123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2536008123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceSpontaneous symmetry breaking occurs when a symmetric system evolves into a lower-symmetry state. In equilibrium systems, this is typically driven by energy minimization, resulting in iconic phenomena such as the buckling of a compressed rod, ... Symmetry-breaking thermomagnetic dynamics of ferrofluid: Oscillation, spontaneous rotation, and flow bistability under laser irradiation doi:10.1073/pnas.2536008123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z Chengzhen QinFeng LinChong WangSuchuan DongZhiming WangJiming Baoahttps://ror.org/0040axw97School of Materials and Energy, Yunnan University, Kunming, Yunnan 650500, People’s Republic of Chinabhttps://ror.org/048sx0r50Materials Science and Engineering Program, University of Houston, Houston, TX 77204chttps://ror.org/048sx0r50Department of Electrical and Computer Engineering and Texas Center for Superconductivity, University of Houston, Houston, TX 77204dhttps://ror.org/02dqehb95Department of Mathematics, Purdue University, West Lafayette, IN 47907eShimmer Center, Tianfu Jiangxi Laboratory, Chengdu, Sichuan 641419, People’s Republic of China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2536008123 https://www.pnas.org/doi/abs/10.1073/pnas.2536008123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2600822123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceThis study establishes an integrated mutagenesis and AI-driven phenotyping framework that accelerates high-throughput deep mutational scanning at residue-level resolution. Applying this approach to human α-tubulin TUBA1A, we generate a ... Comprehensive mutagenesis defines the functional landscape of human α-tubulin doi:10.1073/pnas.2600822123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z Kaiming XuZhengyang GuoZihan ChenMing LiZongxian ChenDeyang ZhangYang WangYongping ChaiJinxiang ZhangHui WangDong LiWei LiGuangshuo Ouahttps://ror.org/03cve4549State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, Beijing Frontier Research Center for Biological Structure, McGovern Institute for Brain Research, Ministry of Education Key Laboratory for Protein Science, School of Life Sciences, Tsinghua University, Beijing 100084, Chinabhttps://ror.org/00p991c53Department of Medical Genetics, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, Chinachttps://ror.org/00p991c53Department of Emergency Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, Chinadhttps://ror.org/03cve4549State Key Laboratory of Membrane Biology, School of Basic Medical Sciences, Tsinghua University, Beijing 100084, China Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2600822123 https://www.pnas.org/doi/abs/10.1073/pnas.2600822123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2535409123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceBecoming a grandparent is a major life transition, yet its consequences for health and work are not fully understood. Using population-wide Norwegian register data, we document how becoming a grandparent alters both health service use and ... The cost of caring: Gendered health and labor market effects of grandparenthood doi:10.1073/pnas.2535409123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z Maria Lyster AndersenRannveig Kaldager HartHans Fredrik SundeNeil Martin DaviesFartein Ask Torvikahttps://ror.org/046nvst19Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo 0476, Norwaybhttps://ror.org/01xtthb56Department of Psychology, University of Oslo, Oslo 0373, Norwaychttps://ror.org/01xtthb56Department of Health Management and Health Economics, Institute of Health and Society, University of Oslo, Oslo 0373, Norwaydhttps://ror.org/02jx3x895Division of Psychiatry, Department of Statistics, University College London, London W1T 7NF, United Kingdomehttps://ror.org/05xg72x27Department of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim 7491, Norwayfhttps://ror.org/01xtthb56Promenta Research Center, Department of Psychology, University of Oslo, Oslo 0373, Norway Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2535409123 https://www.pnas.org/doi/abs/10.1073/pnas.2535409123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2605754123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceUnderstanding how academic knowledge is produced is essential for maintaining public trust in science. Large language models (LLMs) such as ChatGPT are rapidly transforming academic writing, yet little is known about who uses these tools or ... The diffusion of large language models in published academic articles doi:10.1073/pnas.2605754123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z Kyle Silerahttps://ror.org/03dbr7087Department of Leadership, Higher and Adult Education, Ontario Institute for Studies in Education, Data, Equity and Policy in Education Lab, University of Toronto, Toronto, ON M5S 1V6 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2605754123 https://www.pnas.org/doi/abs/10.1073/pnas.2605754123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2606521123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceMarine upper-tropospheric new particle formation (NPF) supports a critical global aerosol reservoir shaping cloud condensation nuclei and Earth’s radiative balance, yet its mechanisms remain highly uncertain for climate models. We reveal that ... Marine upper-tropospheric rapid particle formation dominated by methanesulfonic acid doi:10.1073/pnas.2606521123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z An NingLizhuo MaoBin ZhaoHaotian ZuJiewen ShenYonggui ZhaoJing LiXiucong DengLing LiuHaijie ZhangJoseph S. FranciscoShuxiao WangXiuhui Zhangahttps://ror.org/01skt4w74State Key Laboratory of Environment Characteristics and Effects for Near-space, Key Laboratory of Cluster Science, Ministry of Education of China, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 100081, ChinabState Key Laboratory of Regional Environment and Sustainability, School of Environment, Tsinghua University, Beijing 100084, ChinacState Environmental Protection Key Laboratory of Sources and Control of Air Pollution Complex, Beijing 100084, Chinadhttps://ror.org/02crff812Department of Chemistry, University of Zurich, Zurich CH-8057, Switzerlandehttps://ror.org/05t8xvx87State Key Laboratory of Environmental Benchmarking and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, Chinafhttps://ror.org/00b30xv10Department of Earth and Environmental Science, University of Pennsylvania, Philadelphia, PA 19104-6316ghttps://ror.org/00b30xv10Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104-6316 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2606521123 https://www.pnas.org/doi/abs/10.1073/pnas.2606521123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2528998123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceExcess nonphononic excitations beyond the Debye theory of phonons are central to understanding amorphous materials. Extensive light, inelastic X-ray, and neutron scattering experiments have documented these excitations in covalent network ... Boson peak in covalent network glasses: Isostaticity and marginal stability doi:10.1073/pnas.2528998123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z Hideyuki MizunoTatsuya MoriGiacomo BaldiEmi Minamitaniahttps://ror.org/057zh3y96Graduate School of Arts and Sciences, The University of Tokyo, Tokyo 153-8902, Japanbhttps://ror.org/02956yf07Department of Materials Science, University of Tsukuba, Ibaraki 305-8573, Japanchttps://ror.org/05trd4x28Department of Physics, University of Trento, Povo (Tn) 38123, Italydhttps://ror.org/035t8zc32The Institute of Scientific and Industrial Research, The University of Osaka, Osaka 567-0047, Japan Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2528998123 https://www.pnas.org/doi/abs/10.1073/pnas.2528998123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2602893123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceFor decades, ecologists have been intrigued by two fundamental interlinked questions: what enables species to coexist, and how does the diversity of coexisting species influence ecosystem functioning? Our research provides a unified answer. ... Mechanistic links between coexistence, productivity, and stability in experimental grasslands doi:10.1073/pnas.2602893123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z Pubin HongBernhard SchmidDylan CravenMaowei LiangMingyu LuoZeyu WangChen YangLibin ZhouEric AllanJane A. CatfordNico EisenhauerYanhao FengYann HautierMengjiao HuangYuanyuan HuangForest IsbellLin JiangMichel LoreauPeter B. ReichChristiane RoscherJasper van RuijvenDavid TilmanAlexandra WeigeltShaopeng Wangahttps://ror.org/02v51f717State Key Laboratory of Vegetation Structure, Function and Construction (VegLab), Institute of Ecology, College of Urban and Environmental Sciences, Peking University, Beijing 100871, Chinabhttps://ror.org/00pn44t17Centro de Genómica, Ecología y Medio Ambiente, Universidad Mayor, Santiago 8580745, ChilecData Observatory Foundation, ANID Technology Center No. DO210001, Eliodoro Yáñez 2990, 7510277, Providencia, Santiago, Chiledhttps://ror.org/017zqws13Cedar Creek Ecosystem Science Reserve, University of Minnesota, East Bethel, MN 55455ehttps://ror.org/01mkqqe32State Key Laboratory of Herbage Improvement and Grassland Agro-ecosystems, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou 730020, Chinafhttps://ror.org/034t30j35State Key Laboratory of Lake and Watershed Science for Water Security, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing 211135, Chinaghttps://ror.org/02k7v4d05Institute of Plant Sciences, University of Bern, 3013 Bern, Switzerlandhhttps://ror.org/02k7v4d05Centre for Development and Environment, University of Bern, 3013 Bern, Switzerlandihttps://ror.org/0220mzb33Department of Geography, King’s College London, London WC2B 4BG, United Kingdomjhttps://ror.org/019wvm592Fenner School of Environment & Society, The Australian National University, Canberra, ACT 2600, Australiakhttps://ror.org/01jty7g66German Centre for Integrative Biodiversity Research (iDiv), Halle-Jena-Leipzig, Leipzig 04103, Germanylhttps://ror.org/03s7gtk40Institute of Biology, Leipzig University, Leipzig 04103, Germanymhttps://ror.org/04pp8hn57Department of Biology, Ecology and Biodiversity Group, Utrecht University, Utrecht 3584 CH, The Netherlandsnhttps://ror.org/00eqwze33Basque Centre for Climate Change, Leioa 48940, Spainohttps://ror.org/017zqws13Department of Ecology, Evolution, and Behavior, University of Minnesota, St. Paul, MN 55108phttps://ror.org/01zkghx44School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332qhttps://ror.org/05d6wfd23Theoretical and Experimental Ecology Station, CNRS, Moulis 09200, Francerhttps://ror.org/017zqws13Department of Forest Resources, University of Minnesota, Saint Paul, MN 55108shttps://ror.org/00jmfr291Institute for Global Change Biology, School for Environment and Sustainability, University of Michigan, Ann Arbor, MI 48104thttps://ror.org/000h6jb29Department of Physiological Diversity, Helmholtz Centre for Environmental Research, Leipzig 04318, Germanyuhttps://ror.org/04qw24q55Forest Ecology and Management Group, Wageningen University & Research, PO Box 47, 6700 AA Wageningen, The Netherlandsvhttps://ror.org/02t274463Bren School of Environmental Science and Management, University of California, Santa Barbara, CA 93117 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2602893123 https://www.pnas.org/doi/abs/10.1073/pnas.2602893123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2605176123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceDuring host colonization or infection, bacteria encounter spatially constrained environments, such as deep-seated infected tissues or abscesses that impose mechanical stress. As they grow under confinement, they generate internal forces whose ... Growth in confinement promotes Pseudomonas aeruginosa tolerance to antibiotics doi:10.1073/pnas.2605176123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z Sourabh MonnappaZainebe Al-MayyahMahmut Selman SakarAlexandre Persatahttps://ror.org/02s376052Institute of Bioengineering and Global Health Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerlandbhttps://ror.org/02s376052Institute of Mechanical Engineering and Bioengineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2605176123 https://www.pnas.org/doi/abs/10.1073/pnas.2605176123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2601408123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceMany cells change shape using actomyosin, but some protists contract using calcium-activated protein networks called myonemes. We combine quantitative imaging, electron microscopy, multiscale modeling, and in vitro reconstitution to link ... A centrin–Sfi1 myoneme fishnet powers ultrafast calcium-triggered contraction in the giant ciliate Spirostomum ambiguum doi:10.1073/pnas.2601408123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z Joseph LannanCarlos FloydL. X. XuPeter M. ThompsonConnie YanWallace F. MarshallSuriyanarayanan VaikuntanathanAaron R. DinnerJerry E. HontsSaad BhamlaMary Williard Eltingahttps://ror.org/04tj63d06Department of Physics and Astronomy, North Carolina State University, Raleigh, NC 27695bhttps://ror.org/024mw5h28Department of Chemistry, University of Chicago, Chicago, IL 60637chttps://ror.org/01zkghx44Department of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA 30332dhttps://ror.org/04tj63d06Department of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, NC 27695ehttps://ror.org/04tj63d06Molecular Education, Technology, and Research Innovation Center, North Carolina State University, Raleigh, NC 27695fhttps://ror.org/043mz5j54Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94158ghttps://ror.org/001skmk61Department of Biology, Drake University, Des Moines, IA 50311hhttps://ror.org/02ttsq026Department of Chemical and Biological Engineering, BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303ihttps://ror.org/04tj63d06Cluster for Quantitative and Computational Developmental Biology, North Carolina State University, Raleigh, NC 27695jhttps://ror.org/04tj63d06Integrative Sciences Initiative, North Carolina State University, Raleigh, NC 27695 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2601408123 https://www.pnas.org/doi/abs/10.1073/pnas.2601408123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2521850123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceThe complex dynamics of fish schools has long fascinated scientists, but the mechanisms leading to such organized collective behavior remain ill-understood and intensely debated. Experimental studies have suggested that hydrodynamic ... Traveling waves in a continuum model of schooling swimmers doi:10.1073/pnas.2521850123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z Anand U. OzaEva KansoMichael J. Shelleyahttps://ror.org/05e74xb87Department of Mathematical Sciences, Center for Applied Mathematics and Statistics, New Jersey Institute of Technology, Newark, NJ 07102bhttps://ror.org/03taz7m60Department of Aerospace and Mechanical Engineering, University of Southern California, Los Angeles, CA 90089chttps://ror.org/03taz7m60Department of Physics and Astronomy, University of Southern California, Los Angeles, CA 90089dhttps://ror.org/037tm7f56Courant Institute of Mathematical Sciences, New York, NY 10012ehttps://ror.org/00sekdz59Center for Computational Biology, Flatiron Institute, New York, NY 10010 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2521850123 https://www.pnas.org/doi/abs/10.1073/pnas.2521850123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2529694123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceMonitored quantum dynamics underpin emerging quantum technologies. This work shows that, in many-body systems, recurrence time—the duration required for the initial state to be first detected again—is fractionally quantized by topology. ... Fractionally quantized recurrence detection times in monitored quantum many-body systems doi:10.1073/pnas.2529694123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z Quancheng LiuSabine TornowDavid A. KesslerEli Barkaiahttps://ror.org/03kgsv495Department of Physics, Bar-Ilan University, Ramat-Gan 52900, Israelbhttps://ror.org/03kgsv495Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat-Gan 52900, Israelchttps://ror.org/05kkv3f82Department of Computer Science, Research Institute CODE (Cyber Defence), University of the Bundeswehr Munich, Munich 81739, Germany Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2529694123 https://www.pnas.org/doi/abs/10.1073/pnas.2529694123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2531880123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>SignificanceUpper Paleolithic and Mesolithic human populations are known to have harvested intertidal mollusks along the southern European coast, often with a marked preference for collection during the colder months of the year. Using oxygen isotope ... Seasonal shellfish exploitation by Neanderthals 115,000 years ago doi:10.1073/pnas.2531880123 Proceedings of the National Academy of Sciences 2026-05-18T07:00:00Z Asier García-EscárzagaIgor Gutiérrez-ZugastiArnaldo MarínJosefina ZapataAdolfo Moreno-MárquezLeon J. ClarkeStefania MilanoGernot NehrkeRonald Castellón-VargasPatrick RobertsJoão ZilhãoAndré C. Coloneseahttps://ror.org/052g8jq94Department of Prehistory and Institute of Environmental Science and Technology (ICTA-UAB), Universitat Autònoma de Barcelona, Bellaterra 08193, Spainbhttps://ror.org/049da5t36IsoTOPIK Lab, Department of History, Geography and Communication, Faculty of Humanities and Communication, University of Burgos, Burgos 09001, Spainchttps://ror.org/046ffzj20BioPrehistory Research Group, Instituto Internacional de Investigaciones Prehistóricas de Cantabria (Universidad de Cantabria, Banco Santander, Gobierno de Cantabria), Santander 39005, Spaindhttps://ror.org/03p3aeb86Departamento de Ecología e Hidrología, Facultad de Biología, Universidad de Murcia, Murcia 30100, Spainehttps://ror.org/03p3aeb86Área de Antropología Física, Facultad de Biología, Universidad de Murcia, Murcia 30100, Spainfhttps://ror.org/003d3xx08Abdera Research Group, Department of Geography, History and Humanities, University of Almería, Almería 04120, Spainghttps://ror.org/02hstj355Department of Natural Sciences, Faculty of Science and Engineering, Manchester Metropolitan University, Manchester M1 5GD, United KingdomhThermo Fisher Scientific GmbH, Dreieich 63303, Germanyihttps://ror.org/032e6b942Alfred Wegener Institut Helmholtz-Zentrum für Polar- und Meeresforschung, Section Marine BioGeoSciences, Bremerhaven 27570, GermanyjSan Luis-Temporal, San Rafael Tarija Ltda. SN., Tarija, Boliviakhttps://ror.org/00js75b59Department of Coevolution of Land Use and Urbanisation, Max Planck Institute of Geoanthropology, Jena 07745, Germanylhttps://ror.org/01c27hj86UNIARQ–Centro de Arqueologia da Universidade de Lisboa, Faculdade de Letras de Lisboa, Universidade de Lisboa, Lisboa 1600-214, Portugal Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2531880123 https://www.pnas.org/doi/abs/10.1073/pnas.2531880123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2607049123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/> Polyploidy and stress doi:10.1073/pnas.2607049123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Douglas E. SoltisDonald T. FoxPamela S. SoltisaPolyploidy Integration and Innovation Institute, University of Florida, Gainesville, FL 32611bFlorida Museum of Natural History, University of Florida, Gainesville, FL 32611cDepartment of Biology, University of Florida, Gainesville, FL 32611dBiodiversity Institute, University of Florida, Gainesville, FL 32611eDepartment of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham NC 27710 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2607049123 https://www.pnas.org/doi/abs/10.1073/pnas.2607049123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2603416123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>Sudden, global reversals in shell coiling direction are a striking and recurrent feature in the fossil record of planktonic foraminifera (marine zooplankton), yet their evolutionary significance has been a mystery. Because coiling direction is a simple, ... Flipping plankton doi:10.1073/pnas.2603416123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Bridget S. WadePaul N. PearsonDavid J. KingValeria LucianiaDepartment of Earth Sciences, University College London, London WC1E 6BT, United KingdombDipartimento di Fisica e Scienze della Terra, Università di Ferrara, Ferrara 44122, Italy Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2603416123 https://www.pnas.org/doi/abs/10.1073/pnas.2603416123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2603690123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>Desert ants and foraging rodents return home along surprisingly direct paths after meandering outward journeys. Traditional path integration models explain this through cumulative vector addition, yet struggle to account for the neurobiological mechanisms ... Path integration in complex number space doi:10.1073/pnas.2603690123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z Paul CraddockYannick MiossecYoucef BouchekiouaaDepartment of Psychology, University of Lille, Villeneuve d’Ascq 59653, FrancebDivision of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2603690123 https://www.pnas.org/doi/abs/10.1073/pnas.2603690123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2613147123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/>The identification ofSRD5A3, a causative gene for congenital disorders of glycosylation (CDGs), together with its yeast orthologDFG10, established the prevailing model that dolichol is synthesized from polyprenol in a single step. Subsequently, a recent ... The revised three-step detour pathway in dolichol biosynthesis is evolutionarily conserved in budding yeast doi:10.1073/pnas.2613147123 Proceedings of the National Academy of Sciences 2026-05-27T07:00:00Z Kazuki HanaokaKuya MatsunagaSouichirou ShimizuSoshi SakaiHarald PichlerKouichi FunatoaProgram of Food and AgriLife Science Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima 739-8528, JapanbSchool of Applied Biological Science, Hiroshima University, Higashi-Hiroshima 739-8528, JapancInstitute of Molecular Biotechnology, Graz University of Technology, NAWI Graz, BioTechMed Graz, Graz 8010, AustriadAustrian Centre of Industrial Biotechnology GmbH, Graz 8010, Austria Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2613147123 https://www.pnas.org/doi/abs/10.1073/pnas.2613147123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2610121123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/> Remote sensing enables expansion of our understanding of controls on river width and active floodplain doi:10.1073/pnas.2610121123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Giovanni SeminaraaDipartimento di Ingegneria Civile, Chimica e Ambientale, Università di Genova, Genova 16145, Italy Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2610121123 https://www.pnas.org/doi/abs/10.1073/pnas.2610121123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2611973123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/> Rates of speciation and past extinctions affect food webs on continental scales doi:10.1073/pnas.2611973123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z P. David PollyaEarth and Atmospheric Sciences, Indiana University, Bloomington, IN 47405bGeosciences and Geography, University of Helsinki, Helsinki 00014, Finland Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2611973123 https://www.pnas.org/doi/abs/10.1073/pnas.2611973123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2612819123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/> A loaf of bread and a jug wine: The origins of the ultimate culinary pairing doi:10.1073/pnas.2612819123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Melinda ZederaDepartment of Anthropology, Smithsonian National Museum of Natural History, Washington, DC 20560 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2612819123 https://www.pnas.org/doi/abs/10.1073/pnas.2612819123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2604228123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/> Ecological replacement versus process-based recovery of Caribbean reefs doi:10.1073/pnas.2604228123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Y. LoyaR. van WoesikaSchool of Zoology, Faculty of Life Sciences, Tel Aviv University, Tel Aviv 6997801, IsraelbInstitute for Global Ecology, Florida Institute of Technology, Melbourne, FL 32901 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2604228123 https://www.pnas.org/doi/abs/10.1073/pnas.2604228123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2610187123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/> Explaining the universality of biological thermal responses doi:10.1073/pnas.2610187123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Jose Ignacio ArroyoChristopher KempesGeoffrey WestPablo A. MarquetaSanta Fe Institute, Santa Fe, NMbCentro de Modelamiento Matemático (CMM), Universidad de Chile, Santiago 8370459, ChilecFacultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago 8331150, ChiledInstituto de Sistemas Complejos de Valparaíso, Valparaíso 2360155, ChileeWissenschaftskolleg zu Berlin, Berlin 14193, Germany Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2610187123 https://www.pnas.org/doi/abs/10.1073/pnas.2610187123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2611331123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/> Intentions poorly explain how and why people engage in offensive and defensive forms of violence doi:10.1073/pnas.2611331123 Proceedings of the National Academy of Sciences 2026-05-22T07:00:00Z Angelo RomanoCarsten K. W. De Dreuahttps://ror.org/027bh9e22Social, Economic, and Organisational Psychology Department, Leiden University, Leiden 2313 BP, the Netherlandsbhttps://ror.org/012p63287Faculty of Economics and Business, Groningen University, Groningen 9747 AE, the Netherlandschttps://ror.org/012p63287Faculty of Behavioral and Social Sciences, University of Groningen, Groningen 9712 TS, the Netherlandsdhttps://ror.org/02f99v835Behavioral Ecology and Sociobiology Unit, German Primate Center; Leibniz Institute for Primate Research, Göttingen 37077, Germany Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2611331123 https://www.pnas.org/doi/abs/10.1073/pnas.2611331123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2610820123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/> Introduced species will not save Caribbean coral reefs doi:10.1073/pnas.2610820123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z R. Ritson-WilliamsP. J. MumbyR. S. SteneckaDepartment of Biology, California State University Northridge, Northridge, CA 91330bMarine Spatial Ecology Lab, School of the Environment, The University of Queensland, St. Lucia, QLD 4072, AustraliacDarling Marine Center, University of Maine, Walpole, ME 04573 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2610820123 https://www.pnas.org/doi/abs/10.1073/pnas.2610820123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2616031123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/> Correction for Gao et al., Cross-linking of collagen fibrils leads to preferential gap zone mineralization in vitro doi:10.1073/pnas.2616031123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2616031123 https://www.pnas.org/doi/abs/10.1073/pnas.2616031123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2615315123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/> Correction for Craig et al., Lipid residue analysis reveals divergent culinary practices in Japan and Korea at the dawn of intensive agriculture doi:10.1073/pnas.2615315123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2615315123 https://www.pnas.org/doi/abs/10.1073/pnas.2615315123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2615850123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/> Correction for Astley et al., Global monitoring of the impact of the COVID-19 pandemic through online surveys sampled from the Facebook user base doi:10.1073/pnas.2615850123 Proceedings of the National Academy of Sciences 2026-05-29T07:00:00Z Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2615850123 https://www.pnas.org/doi/abs/10.1073/pnas.2615850123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2613434123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/> Reply to Romano and De Dreu: Why violent extremism cannot be reduced to laboratory games doi:10.1073/pnas.2613434123 Proceedings of the National Academy of Sciences 2026-05-22T07:00:00Z Jonas R. KunstTomasz BestaMilan Obaidiahttps://ror.org/03ez40v33Department of Communication and Culture, BI Norwegian Business School, Oslo 0484, NorwaybInstitute of Psychology, University of Gdańsk, Gdańsk 80-309, Polandchttps://ror.org/035b05819Department of Psychology, University of Copenhagen, 1353 Copenhagen, Denmark Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2613434123 https://www.pnas.org/doi/abs/10.1073/pnas.2613434123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2612489123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/> Reply to Ritson-Williams et al. and Loya and van Woesik: Coral replacement research is vital due to uncertainty and unprecedented stress doi:10.1073/pnas.2612489123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Alejandro E. CamachoDavid A. DanaMikhail Matzahttps://ror.org/046rm7j60School of Law, University of California, Los Angeles, Los Angeles, CA 92651bPritzker School of Law, Northwestern University, Chicago, IL 60611chttps://ror.org/00hj54h04Department of Integrative Biology, University of Texas at Austin, Austin, TX 78712 Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2612489123 https://www.pnas.org/doi/abs/10.1073/pnas.2612489123?af=R https://www.pnas.org/doi/abs/10.1073/pnas.2612681123?af=R Proceedings of the National Academy of Sciences, Volume 123, Issue 22, June 2026. <br/> Reply to Arroyo et al.: Universality and diversity in thermal performance curves doi:10.1073/pnas.2612681123 Proceedings of the National Academy of Sciences 2026-05-26T07:00:00Z Jean-Francois ArnoldiAndrew L. JacksonIgnacio Peralta-MaraverNicolas Payneahttps://ror.org/05d6wfd23Theoretical and Experimental Ecology Station, CNRS Moulis, Moulis 09200, Francebhttps://ror.org/02tyrky19Department of Zoology, School of Natural Sciences, Trinity College Dublin, Dublin D02 PN40, Irelandchttps://ror.org/04njjy449Departamento de Ecología, Universidad de Granada, Granada 18071, Spaindhttps://ror.org/04njjy449Research Unit Modeling Nature, Universidad de Granada, Granada 18071, Spain Proceedings of the National Academy of Sciences 123 22 2026-06-02T07:00:00Z 2026-06-02T07:00:00Z 10.1073/pnas.2612681123 https://www.pnas.org/doi/abs/10.1073/pnas.2612681123?af=R