https://www.brainline.org/rss/allcontent.xml en https://www.brainline.org/research/mild-traumatic-brain-injuries-and-risk-affective-and-behavioral-disorders Children who sustain an mTBI are at increased risk for developing new affective or behavioral disorders over four-years post-injury. Fri, 26 Jan 2024 10:21:19 EST BrainLine https://www.brainline.org/research/mild-traumatic-brain-injuries-and-risk-affective-and-behavioral-disorders https://www.brainline.org/research/psychotherapy-effective-treating-ptsd-following-exposure-multiple-traumatic-events-single Psychotherapy is as effective treatment for PTSD patients after multiple traumatic events. Fri, 12 Jan 2024 12:27:30 EST BrainLine https://www.brainline.org/research/psychotherapy-effective-treating-ptsd-following-exposure-multiple-traumatic-events-single https://www.brainline.org/research/childhood-stress-has-greater-genetic-impact-brain-injury A surprising thing happened when researchers began exploring whether early-life stress compounds the effects of a childhood head injury on health and behavior later in life: In an animal study, stress changed the activation level of many more genes in the brain than were changed by a bump to the head. Wed, 15 Nov 2023 10:35:52 EST BrainLine https://www.brainline.org/research/childhood-stress-has-greater-genetic-impact-brain-injury https://www.brainline.org/research/serious-brain-trauma-chronic-traumatic-encephalopathy-cte-found-young-athletes In this case series of 152 contact sport athletes younger than 30 years at the time of death, chronic traumatic encephalopathy (CTE) was found in 63 (41.4%), with nearly all having mild CTE (stages I and II).  Wed, 13 Sep 2023 15:39:26 EDT BrainLine https://www.brainline.org/research/serious-brain-trauma-chronic-traumatic-encephalopathy-cte-found-young-athletes https://www.brainline.org/research/collective-force-head-hits-not-just-number-them-increases-odds-cte Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy associated with repetitive head impacts. These findings implicate cumulative head impact intensity in CTE pathogenesis. Fri, 23 Jun 2023 14:15:58 EDT BrainLine https://www.brainline.org/research/collective-force-head-hits-not-just-number-them-increases-odds-cte https://www.brainline.org/research/historic-review-repetitive-head-impacts-and-chronic-traumatic-encephalopathy Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with a history of repetitive head impacts (RHI). To better understand the strength of evidence underlying the possible causal relationship between RHI and CTE, we examined the medical literature through the Bradford Hill criteria for causation. Mon, 13 Feb 2023 09:14:32 EST BrainLine https://www.brainline.org/research/historic-review-repetitive-head-impacts-and-chronic-traumatic-encephalopathy https://www.brainline.org/research/female-athletes-may-be-more-susceptible-concussion-and-have-prolonged-symptoms-after Female athletes are more susceptible to sport-related concussions (SRCs) and experience worse outcomes compared with male athletes. Although numerous studies on SRC have compared the outcomes of concussions in male and female athletes after injury, research pertaining to why female athletes have worse outcomes is limited. Tue, 07 Feb 2023 12:04:26 EST BrainLine https://www.brainline.org/research/female-athletes-may-be-more-susceptible-concussion-and-have-prolonged-symptoms-after https://www.brainline.org/research/treatment-protocol-concussions-children-may-need-change A study involving more than 1,500 found that an earlier return to school benefited children ages 8 to 18, who had less severe symptoms two weeks after their concussion compared with kids who stayed home longer. Thu, 02 Feb 2023 09:50:24 EST BrainLine https://www.brainline.org/research/treatment-protocol-concussions-children-may-need-change https://www.brainline.org/research/three-or-more-concussions-linked-worse-brain-function-later-life Experiencing three or more concussions is linked with worsened brain function in later life, according to major new research. The study – the largest of its kind - also found having just one moderate-to-severe concussion, or traumatic brain injury (TBI), can have a long-term impact on brain function, including memory. Tue, 31 Jan 2023 09:23:37 EST BrainLine https://www.brainline.org/research/three-or-more-concussions-linked-worse-brain-function-later-life https://www.brainline.org/research/newly-discovered-anatomy-shields-and-monitors-brain The traditional view is that the brain is surrounded by three layers, the dura, arachnoid, and pia mater. Møllgård et al. found a fourth meningeal layer called the subarachnoid lymphatic-like membrane (SLYM). SLYM is immunophenotypically distinct from the other meningeal layers in the human and mouse brain and represents a tight barrier for solutes of more than 3 kilodaltons, effectively subdividing the subarachnoid space into two different compartments. SLYM is the host for a large population of myeloid cells, the number of which increases in response to inflammation and aging, so this layer represents an innate immune niche ideally positioned to surveil the cerebrospinal fluid. Tue, 24 Jan 2023 11:05:00 EST BrainLine https://www.brainline.org/research/newly-discovered-anatomy-shields-and-monitors-brain