SAN DIEGO, CA--(Marketwire - May 25, 2012) - La Jolla Pharmaceutical Company ( OTCQB : LJPC ) ( PINKSHEETS : LJPC ) (the "Company" and "La Jolla") held its 2012 Annual Meeting of Stockholders on May 22. All matters submitted to a vote of the stockholders at the Annual Meeting were approved and all director nominees were elected.

The stockholders approved the following proposals 1) election of George Tidmarsh, M.D., Ph.D. to serve as a director until the 2014 Annual Meeting, 2) election of Saiid Zarrabian to serve as a director until the 2015 Annual Meeting, 3) ratification of BDO USA, LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2012; 4) amendment of the Company's 2010 Equity Incentive Plan to increase the number of shares that are available for issuance, and 5) approval of the change in the Company's corporate domicile from Delaware to California.

A high percentage of shares (90.3%) were voted. A total of 10,732,261 shares of common stock were present or represented by valid proxy at the Annual Meeting. The number of shares of common stock entitled to vote was 11,884,137.

The number of votes cast for and against and the number of abstentions and broker non-votes with respect to each matter voted upon are set forth below:

(i) (A) Election of one Class I Director

Director Nominee
Saiid Zarrabian
8,161,125 Votes For, 8,547 Votes Withheld.

(i) (B) Election of one Class III Director

Director Nominee
George Tidmarsh, M.D., Ph.D.
8,161,055 Votes For, 8,617 Votes Withheld.
There were 2,562,589 broker non-votes regarding the election of directors.

(ii) Ratification of BDO USA, LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2012

10,570,326 votes for, 161,677 votes against, and 258 votes abstained.
There were no broker non-votes regarding this proposal.

(iii) Approval of an amendment to the La Jolla Pharmaceutical Company 2010 Equity Incentive Plan to increase the number of shares that are available for issuance

8,147,206 votes for, 12,091 votes against, and 10,375 votes abstained.
There were 2,562,589 broker non-votes regarding this proposal.

(iv) Approval of the change in the Company's corporate domicile from Delaware to California

8,157,020 votes for, 11,399 votes against, and 1,253 votes abstained.
There were 2,562,589 broker non-votes regarding this proposal.

About La Jolla Pharmaceutical Company
La Jolla Pharmaceutical Company is a biopharmaceutical company dedicated to the development of treatments that significantly improve outcomes in patients with life-threatening diseases. GCS-100, the Company's product candidate, is a first-in-class inhibitor of galectin-3, a novel molecular target implicated in cancer and chronic organ failure.

Forward Looking Statement Safe Harbor
This document contains forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995. These statements relate to future events or our future results of operations. These statements are only predictions and involve known and unknown risks, uncertainties and other factors, which may cause actual results to be materially different from these forward-looking statements. The Company cautions readers not to place undue reliance on any such forward-looking statements, which speak only as of the date they were made. Certain of these risks, uncertainties, and other factors are described in greater detail in the Company's filings from time to time with the U.S. Securities and Exchange Commission (SEC), all of which are available free of charge on the SEC's web site at http://www.sec.gov. These risks include, but are not limited to, risks relating to the development of GCS-100, the success and timing of future preclinical and clinical studies of this compound, and potential indications for which GCS-100 may be developed. Subsequent written and oral forward-looking statements attributable to the Company or to persons acting on its behalf are expressly qualified in their entirety by the cautionary statements set forth in the Company's reports filed with the SEC. The Company expressly disclaims any intent to update any forward-looking statements.

SAN DIEGO, CA--(Marketwire - May 25, 2012) - La Jolla Pharmaceutical Company ( OTCQB : LJPC ) ( PINKSHEETS : LJPC ) (the "Company" and "La Jolla") held its 2012 Annual Meeting of Stockholders on May 22. All matters submitted to a vote of the stockholders at the Annual Meeting were approved and all director nominees were elected.

The stockholders approved the following proposals 1) election of George Tidmarsh, M.D., Ph.D. to serve as a director until the 2014 Annual Meeting, 2) election of Saiid Zarrabian to serve as a director until the 2015 Annual Meeting, 3) ratification of BDO USA, LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2012; 4) amendment of the Company's 2010 Equity Incentive Plan to increase the number of shares that are available for issuance, and 5) approval of the change in the Company's corporate domicile from Delaware to California.

A high percentage of shares (90.3%) were voted. A total of 10,732,261 shares of common stock were present or represented by valid proxy at the Annual Meeting. The number of shares of common stock entitled to vote was 11,884,137.

The number of votes cast for and against and the number of abstentions and broker non-votes with respect to each matter voted upon are set forth below:

(i) (A) Election of one Class I Director

Director Nominee
Saiid Zarrabian
8,161,125 Votes For, 8,547 Votes Withheld.

(i) (B) Election of one Class III Director

Director Nominee
George Tidmarsh, M.D., Ph.D.
8,161,055 Votes For, 8,617 Votes Withheld.
There were 2,562,589 broker non-votes regarding the election of directors.

(ii) Ratification of BDO USA, LLP as the Company's independent registered public accounting firm for the fiscal year ending December 31, 2012

10,570,326 votes for, 161,677 votes against, and 258 votes abstained.
There were no broker non-votes regarding this proposal.

(iii) Approval of an amendment to the La Jolla Pharmaceutical Company 2010 Equity Incentive Plan to increase the number of shares that are available for issuance

8,147,206 votes for, 12,091 votes against, and 10,375 votes abstained.
There were 2,562,589 broker non-votes regarding this proposal.

(iv) Approval of the change in the Company's corporate domicile from Delaware to California

8,157,020 votes for, 11,399 votes against, and 1,253 votes abstained.
There were 2,562,589 broker non-votes regarding this proposal.

About La Jolla Pharmaceutical Company
La Jolla Pharmaceutical Company is a biopharmaceutical company dedicated to the development of treatments that significantly improve outcomes in patients with life-threatening diseases. GCS-100, the Company's product candidate, is a first-in-class inhibitor of galectin-3, a novel molecular target implicated in cancer and chronic organ failure.

Forward Looking Statement Safe Harbor
This document contains forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995. These statements relate to future events or our future results of operations. These statements are only predictions and involve known and unknown risks, uncertainties and other factors, which may cause actual results to be materially different from these forward-looking statements. The Company cautions readers not to place undue reliance on any such forward-looking statements, which speak only as of the date they were made. Certain of these risks, uncertainties, and other factors are described in greater detail in the Company's filings from time to time with the U.S. Securities and Exchange Commission (SEC), all of which are available free of charge on the SEC's web site at http://www.sec.gov. These risks include, but are not limited to, risks relating to the development of GCS-100, the success and timing of future preclinical and clinical studies of this compound, and potential indications for which GCS-100 may be developed. Subsequent written and oral forward-looking statements attributable to the Company or to persons acting on its behalf are expressly qualified in their entirety by the cautionary statements set forth in the Company's reports filed with the SEC. The Company expressly disclaims any intent to update any forward-looking statements.

SAN DIEGO, CA--(Marketwire - May 24, 2012) - The X PRIZE Foundation and Nokia today announced the launch of the Nokia Sensing X CHALLENGE, a $2.25 million global competition to stimulate the development of a new generation of health sensors and sensing technologies that can drastically improve the quality, accuracy and ease of monitoring a person's health. Improvements in these technologies will empower individuals to effortlessly monitor and collect their own real-time health data, providing both consumers and healthcare providers convenient access to critical information whenever and wherever they need it.

The announcement was made by X PRIZE Foundation Chairman and CEO Dr. Peter H. Diamandis and Nokia Executive Vice President and Chief Technology Officer Dr. Henry Tirri during their keynote address at the Wireless Health Convergence Summit in San Diego, Calif.

"Partnering with Nokia is a natural fit for this competition. Health sensing technologies enabled by artificial intelligence, lab-on-a-chip, and digital imaging are advancing exponentially and will ultimately integrate with your phone. We need to expand sensor and sensing technology beyond disease management to areas such as public health and fitness," said Dr. Diamandis. "The Nokia Sensing X CHALLENGE will bring about radical innovation in health sensors and sensing technologies, which paves the way for better choices in when, where, and how individuals receive care. Ultimately, healthcare will be more convenient, affordable, and accessible to consumers worldwide through these integrated digital health solutions."

The inefficiencies and total cost of the U.S. healthcare system (and healthcare systems around the globe) has been a pressing social and political issue for many years. In the U.S., the total spent annually on the healthcare system is more than $2 trillion¹, which accounts for more than 15 percent of the nation's gross domestic product. Health sensors have the capacity to stem this trend. Consumer use of sensors and sensing solutions has the potential to improve, extend and ease delivery of healthcare services, as well as reduce costs to the benefit of health providers and patients.

"Nokia engages in Open Innovation on many different levels; this type of 'grand challenge' is not only a unique method of driving significant progress in a short space of time, but one which can also help to create an entire ecosystem," said Dr. Tirri. "This competition will enable us to realize the full potential of mobile sensing devices, leading to advances in sensing technology, which can play a major role in transforming the lives of billions of people around the world."

The Nokia Sensing X CHALLENGE will be a series of three competition events, held over the next three years. Each event will be comprised of three phases: Registration, Preliminary Judging and Final Phase Judging. The winners of each competition will be the teams that submit best in class technology as determined by a non-partisan judging panel of cross-functional industry experts.

It is anticipated that the solutions developed as part of the Nokia Sensing X CHALLENGE may also be utilized as part of a team's effort to win the $10 million Qualcomm Tricorder X PRIZE, which was announced at the 2012 Consumer Electronics Show (CES) during Qualcomm Incorporated Chairman and CEO and Qualcomm Foundation Chair Dr. Paul Jacobs' keynote address. The Qualcomm Tricorder X PRIZE is a global competition aiming to drive development of devices that allow consumers access to healthcare in the palm of their hands. The Nokia Sensing X CHALLENGE and Qualcomm Tricorder X PRIZE will help create an ecosystem of innovators and innovative technology that will help reinvent the healthcare industry and radically reduce the cost to consumers.

For more information about the Nokia Sensing X CHALLENGE, visit: nokiasensingxchallenge.org.

About X PRIZE Foundation
Founded in 1995, the X PRIZE Foundation, a 501(c)(3) nonprofit, is the leading organization solving the world's Grand Challenges by creating and managing large-scale, high-profile, incentivized prize competitions that stimulate investment in research and development worth far more than the prize itself. The organization motivates and inspires brilliant innovators from all disciplines to leverage their intellectual and financial capital for the benefit of humanity. The X PRIZE Foundation conducts competitions in five Prize Groups: Education; Exploration; Energy & Environment; Global Development; and Life Sciences. Active prizes include the $30 million Google Lunar X PRIZE, the $10 million Archon Genomics X PRIZE presented by Express Scripts, the $10 million Qualcomm Tricorder X PRIZE, and the $2.25 million Nokia Sensing X CHALLENGE. For more information, go to www.xprize.org.

About Nokia
Nokia is a global leader in mobile communications whose products have become an integral part of the lives of people around the world. Every day, more than 1.3 billion people use their Nokia to capture and share experiences, access information, find their way or simply to speak to one another. Nokia's technological and design innovations have made its brand one of the most recognized in the world. For more information, visit http://www.nokia.com/about-nokia.

Social Tags:

• Facebook: Nokia Sensing X CHALLENGE
• Twitter: @NokiaXCHALLENGE, hashtag: #sensing

TRICORDER is a trademark of CBS Studios, Inc. used under license. Qualcomm is a registered trademark of Qualcomm Incorporated. All other trademarks are the property of their respective owners.

¹Centers for Medicare & Medicaid Services, Office of the Actuary, National Health Statistics Group; U.S. Department of Commerce, Bureau of Economic Analysis; and U.S. Bureau of the Census. Retrieved from https://www.cms.gov/Research-Statistics-Data-and-Systems/Statistics-Trends-and-Reports/NationalHealthExpendData/downloads//tables.pdf

SAN DIEGO, CA--(Marketwire - May 24, 2012) - True Diagnostics, Inc.T (www.TrueDiagnostics.com) has announced it has received a CE Mark to allow it to distribute its TrueDX Platform and quantitative TSH (Thyroid Stimulating Hormone) test in Europe. With the TrueDX Platform, doctors can immediately determine if a patient suffers from a hypoactive thyroid by using only a finger prick of blood. This unique test enables doctors and patients to gain access to diagnosis in minutes, create an effective treatment plan, while saving physicians' time and patients cost and anxiety. True Diagnostics is actively engaging distribution partners throughout all EU markets, with initial focus in Germany, UK, France, Italy and Spain.

This is the second regulatory clearance for the TrueDX Platform with TSH test, having received sFDA approval for China in September 2011. True Diagnostics expects to run short clinical studies in the U.S. this summer and further submit for CLIA-waive and 510k FDA clearance to market the TrueDX Platform with quantitative TrueDX-TSHT Tests throughout the U.S.

What will the TrueDX Platform mean for doctors and patients seeking to more easily identify Hypoactive Thyroid? Hypothyroidism affects over 200 million people globally, more than people with diabetes. TSH is the fourth most requested blood test in America. Hypothyroidism is commonly undiagnosed and misdiagnosed with symptoms ranging from weight gain to depression, forgetfulness, hair loss, thinning and drying of skin, fatigue, loss of libido, feeling cold, constipation, and a pronounced goiter.

Jerry Lee, President/CEO of True Diagnostics, notes, "With this latest regulatory clearance, the Company has laid the foundation to begin standardizing a full range of diagnostic and monitoring tests that will provide instant results to doctors and patients and demand little training. With distribution partners already lined up and more coming soon, we expect initial shipments to Europe to begin within 60 days."

The strength of the TrueDX Platform lies in its simplicity. Tests have a 24-month shelf life. They do not need to be refrigerated. Laboratory quality results from small samples can now be available to doctors to review in minutes. The TrueDX Platform's simplicity, portability, and affordability allow it to be easily adopted into emerging markets. The platform's flexible design also permits it to stay ahead of potential competitors and quickly commercialize a myriad of new biomarkers discoveries for cancer, autism, alzheimer's, diabetes, drugs of abuse, infectious diseases, cardiac health, traumatic brain injury, viral and bacterial infections, and more. In essence, any biomarker discovery utilizing traditional lab methods, such as an ELISA process, can now be developed into a simple, fast, and portable assay which can offer quick diagnosis and treatment right in the physician's office.

About the Company
True Diagnostics, Inc. creates simple diagnostic solutions for the $46 billion medical point-of-care, sterility assurance, animal health, and food processing markets. After 30 years in the global medical diagnostic field, the inventor of the home pregnancy test created the TrueDX Platform which can measure the severity of any medical condition (using only a finger prick of blood, small urine or saliva sample, toxins, surface bacteria, and more), provide results in minutes (not days), and is completely portable. The TrueDX Platform takes point-of-care, point-of-incidence, and remote-of-care applications out of the lab to provide more flexible treatment that can begin immediately. The TrueDX Platform creates unique and powerful opportunities for new diagnostic solutions through its ability to: 1) quickly bring new diagnostic tests to market; and, 2) open new geographic and application opportunities.

For more information, call 760-683-9158 or go to www.TrueDiagnostics.com

SAN DIEGO, CA--(Marketwire - May 23, 2012) - Cytori Therapeutics ( NASDAQ : CYTX ) will present and provide a corporate update from the Jefferies 2012 Global Healthcare Conference on Tuesday, June 5, 2012 at 10:00 AM ET.

The presentation will be webcast and may be accessed under "Webcasts" on Cytori's Investor Relations website (ir.cytori.com). The webcast can be viewed live and will be available for replay after the presentation on the Company's website.

About Cytori
Cytori Therapeutics is developing cell therapies based on autologous adipose-derived regenerative cells (ADRCs) to treat cardiovascular disease and repair soft tissue defects. Our scientific data suggest ADRCs improve blood flow, moderate the immune response and keep tissue at risk of dying alive. As a result, we believe these cells can be applied across multiple "ischemic" conditions. These therapies are made available to the physician and patient at the point-of-care by Cytori's proprietary technologies and products, including the Celution® system product family. www.cytori.com

SAN DIEGO, CA--(Marketwire - May 21, 2012) - Aegis Therapeutics LLC announced today that it has been awarded U.S. Patent No. 8,133,863 providing broad protection for pharmaceutical composition of octreotide. The highly stable octreotide formulations incorporate Aegis' Intravail®/ProTek® excipients suitable for all routes of administration including oral, buccal, metered nasal spray, or injection. Intravail® and ProTek® excipients allow for non-invasive delivery with high efficiency. They stabilize, prevent aggregation, and reduce unwanted immunogenicity of protein and peptide therapeutics while avoiding the oxidative damage caused by polysorbate surfactants currently found in many protein injectable drugs.

Octreotide is a peptide hormone that mimics natural somatostatin pharmacologically. Octreotide is used to treat acromegaly, severe diarrhea and flushing episodes associated with metastatic carcinoid tumors, and profuse watery diarrhea associated with Vasoactive Intestinal Peptide Tumors (VIPomas).

A published preclinical study conducted at Albany Medical College by Dr. Patricia Grasso demonstrated that formulations of octreotide incorporating Aegis' Intravail®/ProTek® excipients show oral bioavailability that equals or exceeds that achieved by injection*, offering the prospect of a "first in class" non-injectable octreotide. Non-injectable dosage forms of previously injectable-only drugs provide greater patient convenience and acceptance, improved compliance, and avoidance of needle-stick injury and disposal problems associated with the use of needles, paving the way to increased market share and substantial growth in overall product sales.

About Aegis Therapeutics
Aegis Therapeutics LLC is a drug delivery technology company commercializing its patented drug delivery and drug formulation technologies through product-specific licenses. For more information about Aegis, please visit: http://www.aegisthera.com.

*Regulatory Peptides 167 (2011) 233-238.

SAN DIEGO, CA--(Marketwire - May 16, 2012) - Aegis Therapeutics LLC announced today that it has been awarded a second patent, U.S. Patent, No. 8,173,594, providing PTH and PTH analog compositions having increased stability and reduced aggregation and aggregation-associated immunogenicity. The stabilized formulations of parathyroid hormone (PTH) and PTH peptide analogs incorporate Aegis' Intravail®/ProTek® excipients suitable for all routes of administration including the non-invasive metered nasal spray delivery route or injection. Intravail® and ProTek® excipients allow for non-invasive delivery with high efficiency and stabilize, prevent aggregation, and reduce unwanted immunogenicity of protein and peptide therapeutics while avoiding the oxidative damage caused by polysorbate surfactants currently found in many protein injectable drugs.

This patent, along with US Patent 8,076,290, has been exclusively licensed to Azelon Pharmaceuticals. All currently approved PTH drug formulations require daily injection. In contrast, Azelon has reported clinical results demonstrating that formulations of teriparatide based upon Aegis' Intravail®/ProTek® show excellent nasal bioavailability offering the prospect of a "first in class" non-injectable PTH drug. Non-injectable dosage forms of previously injectable-only drugs provide greater patient convenience and acceptance, improved compliance, and avoidance of needle-stick injury and disposal problems associated with the use of needles, paving the way to increased market share and substantial growth in overall product sales.

Licenses for non-invasive delivery and stabilization of human growth hormone; GLP-1 analogs; alpha, beta, and gamma interferon; and other drugs are currently available from Aegis with additional patent issuances to be announced shortly.

About Aegis Therapeutics

Aegis Therapeutics LLC is a drug delivery technology company commercializing its patented drug delivery and drug formulation technologies through product-specific licenses. For more information about Aegis, please visit: http://www.aegisthera.com.

SAN DIEGO, CA--(Marketwire - May 9, 2012) - During the first quarter of 2012, Cytori Therapeutics ( NASDAQ : CYTX ) advanced its cardiac cell therapy product pipeline, grew the commercial business, and strengthened operational and financial performance, which encompasses management of expenses, strategic partnerships, and regulatory approvals. Of the seven active partnership discussions, the Company is focused on the two most advanced transactions with the goal of completing the first partnership in the near term.

Cytori has accomplished the following milestones year-to-date:

Pipeline

• Received approval from the FDA to begin the U.S. ATHENA IDE trial for chronic myocardial ischemia (CMI); all five centers have been identified and enrollment of the first patient is anticipated in the second quarter;
• Published clinical data from two company-sponsored European trials: the APOLLO cardiac cell therapy heart attack pilot trial and the RESTORE 2 post-marketing breast reconstruction trial;
• Completed multiple meetings with the European regulatory body to review clinical data, specifics on claims and negotiate details on potential patient registry toward CE Mark approval for no-option CMI; providing additional data upon the Notified Body's request; decision expected in 2012;

Commercial Business

• Continued to build market access for breast reconstruction in Europe; submitted a medical technology assessment application in the UK;
• Grew commercial business; product revenues increased by 9% compared to Q1 2011; reaffirm $9 million revenue guidance for 2012;

Operational and Financial Performance

• Reduced total operating expenses by 31% and the operating cash burn rate by 27% as compared to Q1 2011;
• Ended the quarter with $34.4 million in cash and cash equivalents, compared with $36.9 million as of year-end 2011;
• Received U.S. composition patent for soft tissue defects and U.S. device patent for accelerating healing of wounds, bringing the total number of issued patents worldwide to 46 with more than 75 applications under review;
• Continued to advance multiple near term partnerships, focused primarily on the two most advanced transactions;

"For our cardiac pipeline, we are placing greater emphasis on our chronic applications, which include the potential CE Mark approval and the U.S. ATHENA trial," said Christopher J. Calhoun, chief executive officer of Cytori. "We have improved operational efficiencies for the commercial business, including year-over-year revenue growth and reduced sales and marketing expenses. Lastly, we are advancing our partnership negotiations, strengthening our IP position and expanding country approvals."

Financial Results

Product revenues were $1.5 million in the first quarter of 2012, compared to $1.4 million in first quarter of 2011. Gross profits were $0.6 million for the first quarter of 2012, compared to $0.5 million for the same period in 2011. As stated in the 2011 year-end release, 2012 sales are expected to be weighted toward the second half of the year and based on internal quarterly projections. Cytori reaffirms guidance of $9 million in product revenue.

Total operating expenses were reduced by 31% to $9.0 million in the first quarter of 2012, compared to $13.0 million in the first quarter of 2011. Operating expenses include non cash costs associated with changes in the fair value of option and warrant liabilities. Net cash used in operating activities was reduced by 27% to $7.7 million in the first quarter of 2012 compared to $10.6 million in the first quarter of 2011. The improvement in total operating expenses and net cash used in operating activities for the first quarter of 2012 as compared to the first quarter of 2011 was due in part to reduced sales and marketing costs and slightly lower clinical trial expenditures.

Net loss was $9.3 million, or ($0.16) per share, for the first quarter of 2012 compared to $12.1 million, or ($0.23) per share, for the first quarter of 2011. At the end of the first quarter of 2012, Cytori had $34.4 million in cash and cash equivalents and $1.4 million in account receivable, net of reserves. This compares to ending 2011 with $36.9 million in cash and cash equivalents and $2.3 million in accounts receivable, net of reserves. Cytori recently terminated its financing agreement with Seaside 88, which raised a total of $18.2 million since we entered the agreement. The primary emphasis is to strengthen the balance sheet by executing one or more development and commercialization partnership agreement(s).

Conference Call, Shareholder Letter and Slide Presentation Information
Cytori will host a management conference call at 5:00 p.m. Eastern Time today to further discuss these results. The live webcast of the conference call may be accessed under "Webcasts" in the Investor Relations section (http://ir.cytori.com) of Cytori's website. The webcast will be available live and by replay two hours after the call. If you are unable to access the webcast, you may dial in to the call at +1.888.208.1815, Passcode: 6625514. More details on our business are contained in the 'May 2012 Shareholder Letter' posted on the homepage of our Investor Relations website.

About Cytori
Cytori Therapeutics is developing cell therapies based on autologous adipose-derived regenerative cells (ADRCs) to treat cardiovascular disease and repair soft tissue defects. Our scientific data suggest ADRCs improve blood flow, moderate the immune response and keep tissue at risk of dying alive. As a result, we believe these cells can be applied across multiple "ischemic" conditions. These therapies are made available to the physician and patient at the point-of-care by Cytori's proprietary technologies and products, including the Celution® system product family. www.cytori.com

Cautionary Statement Regarding Forward-Looking Statements
This press release includes forward-looking statements regarding events, trends and business prospects, which may affect our future operating results and financial position, such as the successful initiation of the ATHENA clinical trial of the Company's Celution® system for chronic myocardial ischemia, our efforts to expand our CE Mark, achieve our revenue projection for 2012, and execute a commercialization partnership agreement. Such statements are subject to risks and uncertainties that could cause our actual results and financial position to differ materially. Some of these risks include clinical and regulatory uncertainties, such as those associated with the ATHENA clinical trial, including risks in the collection and results of clinical data, final clinical outcomes, dependence on third party performance, performance and acceptance of our products in the marketplace, and other risks and uncertainties described under "Risk Factors" in Cytori's Securities and Exchange Commission Filings. We assume no responsibility to update or revise any forward-looking statements to reflect events, trends or circumstances after the date they are made.

SAN DIEGO, CA--(Marketwire - May 8, 2012) - Bio-Matrix Scientific Group, Inc. ( OTCQB : BMSN ) ( PINKSHEETS : BMSN ) announced today that J. Christopher Mizer has joined the Company as President and Chief Operating Officer of its Regen BioPharma subsidiary. Regen BioPharma is a "superincubator" focused on accelerated development of undervalued intellectual property in the area of stem cells therapies. Mr. Mizer will spearhead license negotiations, development of academic and corporate partnerships, creation of business units, and value optimization of technologies that are being advanced by Regen BioPharma.

David Koos, Chairman & CEO of Bio-Matrix Scientific Group, stated, "We are building a world-class team in the field of translational, regenerative medicine. Mr. Mizer's solid track record of building companies, attracting funding, attaining profitability, and enabling successful exist strategies uniquely positions him to lead the operational aspects of our novel stem cell company."

Mr. Mizer is the founder of Vivaris, Ltd., a private investment partnership focused on life science and healthcare opportunities, and co-founder of ChinaBio Capital Partners. He was formerly an investment banker with Key Capital Markets and a consultant with Ernst and Young. He holds a Master of Science degree in biology and an M.B.A. from Case Western Reserve University.

About Bio-Matrix Scientific Group, Inc.:

Bio-Matrix Scientific Group, Inc. ( OTCQB : BMSN ) ( PINKSHEETS : BMSN ) is a biotechnology company focused on the development of regenerative medicine therapies and tools. The Company is specifically focused on human therapies that address unmet medical needs. Specifically, Bio-Matrix Scientific Group Inc. is looking to increase the quality of life through therapies involving stem cell treatments. These treatments are focused in areas relating to lung, heart, circulatory system and other internal organs.

Through Its wholly owned subsidiary, Regen BioPharma, it is the Company's goal to develop translational medicine platforms for the rapid commercialization of stem cell therapies. The Company is looking to use these translational medicine platforms to advance intellectual property licensed from entities, institutions and universities that show promise towards fulfilling the Company's goal of increased quality of life.

Areas of interest to the Company include:

• Diabetes
• Chronic Obstructive Pulmonary Disease (COPD)
• Heart Related illness
• Circulatory issues

Disclaimer

This news release may contain forward-looking statements. Forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted or quantified. Future events and actual results could differ materially from those set forth in, contemplated by, or underlying the forward-looking statements. The risks and uncertainties to which forward-looking statements are subject include, but are not limited to, the effect of government regulation, competition and other material risks.

SAN DIEGO, CA--(Marketwire - May 7, 2012) - Ardea Biosciences, Inc. ( NASDAQ : RDEA ), a biotechnology company focused on the development of small-molecule therapeutics for the treatment of serious diseases, today announced first quarter 2012 financial results.

On April 22, 2012, AstraZeneca and Ardea Biosciences announced that they had entered into a definitive merger agreement pursuant to which AstraZeneca will acquire Ardea for $32 per share in cash for a total transaction value of approximately $1.26 billion.

First Quarter 2012 Financial Results

As of March 31, 2012, we had $212.9 million in cash, cash equivalents and short-term investments and $2.0 million in receivables, compared to $96.0 million in cash, cash equivalents and short-term investments and $1.4 million in receivables as of December 31, 2011.

The net increase in cash, cash equivalents, short-term investments and receivables in 2012 was due primarily to our February 2012 public offering of common stock, which resulted in net proceeds to us of $157.3 million. This increase was partially offset by the use of cash to fund our clinical-stage programs, personnel costs and for other general corporate purposes during the first quarter of 2012.

Revenues totaled $1.5 million and $1.8 million for the three months ended March 31, 2012 and 2011, respectively. The decrease in revenues in 2012 as compared to 2011 was primarily due to a decrease in reimbursable research and development costs related to BAY86-9766 (RDEA119), which are reimbursed under the terms of our global license agreement with Bayer HealthCare.

For the three months ended March 31, 2012, total operating expenses increased to $42.5 million from $17.0 million for the same period in 2011. Total operating expenses for the three months ended March 31, 2012 included non-cash, stock-based compensation charges of $3.1 million, or $0.09 per share, compared to $2.4 million, or $0.09 per share, for the same period in 2011. The increase in total operating expenses for the three months ended March 31, 2012, compared to the same period in 2011, was primarily a result of an increase in development expenses due to the progression of lesinurad in Phase 3 clinical studies and costs associated with a Phase 1 study for our next-generation product candidate for the chronic treatment of gout, RDEA3170, as well as an increase in consulting and professional outside services and personnel and related costs to support these increased development activities.

Net loss for the three months ended March 31, 2012 was $40.9 million, or $1.25 per share, compared to a net loss for the same period in 2011 of $15.2 million, or $0.59 per share. The increase in net loss for the three months ended March 31, 2012 was due primarily to the operating expense fluctuations described above. The increase in net loss per share for the three months ended March 31, 2012 compared to the same period in 2011 was mainly due to the increase in net loss noted above, partially offset by an increase in weighted-average shares outstanding in 2012 as a result of our February 2011 and 2012 public offerings of common stock.

* Includes $3.1 million in non-cash, stock-based compensation expense for the three months ended March 31, 2012, as compared to $2.4 million for the same period in 2011.

About Ardea
Ardea is a biotechnology company based in San Diego, California, focused on the development of small-molecule therapeutics for the treatment of serious diseases. Ardea's most advanced clinical-stage product candidates include lesinurad, formerly known as RDEA594, a selective, oral URAT1 transporter inhibitor for the chronic management of hyperuricemia in patients with gout and BAY 86-9766, formerly known as RDEA119, a specific inhibitor of mitogen-activated ERK kinase (MEK) for the treatment of cancer which is being developed under a global license agreement with Bayer HealthCare. For more information please visit: www.ardeabio.com

Forward-Looking Statements
Statements contained in this communication regarding matters that are not historical facts are "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Such statements include, but are not limited to, statements regarding the timing and anticipated completion of the proposed merger, the benefits and synergies expected to result from the proposed merger, the anticipated customer base for Ardea following the completion of the proposed merger, Ardea's plans and goals, the expected properties and benefits of lesinurad, BAY 86-9766 (RDEA119), RDEA3170 and Ardea's other compounds and the timing and results of Ardea's preclinical, clinical and other studies, and other statements that are not purely statements of historical fact. These forward-looking statements are made on the basis of the current beliefs, expectations and assumptions of the management of Ardea and are subject to significant risks and uncertainty. Investors are cautioned not to place undue reliance on any such forward-looking statements. Risks that contribute to the uncertain nature of the forward-looking statements include any difficulties associated with integrating Ardea's drug development programs into AstraZeneca's operations, potential adverse reactions or changes to business relationships resulting from the announcement or completion of the proposed merger, unexpected costs, charges or expenses resulting from the proposed merger, litigation or adverse judgments relating to the proposed merger, risks relating to the consummation of the contemplated merger, including the risk that the required stockholder approval might not be obtained in a timely manner or at all or that other closing conditions will not be satisfied, any difficulties associated with requests or directions from governmental authorities resulting from their reviews of the transaction, and any changes in general economic and/or industry-specific conditions, risks related to the outcome of preclinical and clinical studies, risks related to regulatory approvals, delays in commencement of preclinical and clinical studies, costs associated with Ardea's drug discovery and development programs, and risks related to the outcome of Ardea's business development activities, including collaboration or license agreements. Certain of these and other risks and uncertainties are described more fully in Ardea's most recently filed SEC documents, including Ardea's Annual Report on Form 10-K and Ardea's Quarterly Reports on Form 10-Q, under the headings "Risk Factors." All forward-looking statements contained in this communication speak only as of the date on which they were made. Ardea undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made.

Additional Information and Where to Find It
In connection with the proposed merger described in this communication (the "Merger"), a proxy statement of Ardea and other materials will be filed with the SEC. COMPANY INVESTORS ARE URGED TO READ THE PROXY STATEMENT AND OTHER MATERIALS CAREFULLY WHEN THEY BECOME AVAILABLE BECAUSE THEY WILL CONTAIN IMPORTANT INFORMATION ABOUT ARDEA AND THE PROPOSED MERGER. Investors will be able to obtain copies of the proxy statement (when available) and other relevant documents filed with the SEC for free from the SEC's website at http://www.sec.gov or from Ardea's website at http://www.ardeabio.com. Stockholders will also be able to obtain copies of the proxy statement and other documents related to the Merger (when available) for free by written request to Ardea Biosciences, Inc., c/o Corporate Secretary, 4939 Directors Place, San Diego, California 92121.

Participants in Solicitation
Ardea and its directors, executive officers and other members of its management and employees may be deemed to be participants in the solicitation of proxies from its stockholders in connection with the proposed Merger. Information about the executive officers and directors of Ardea and their ownership of Ardea's common stock is set forth in the proxy statement for Ardea's 2012 Annual Meeting of Stockholders filed with the SEC on April 10, 2012. Certain directors and executive officers of Ardea may have direct or indirect interests in the Merger due to securities holdings, pre-existing or future indemnification arrangements, vesting of options or other securities or rights to severance payments if their employment is terminated following the Merger. Additional information regarding Ardea and the interests of its executive officers and directors in the Merger will be contained in the proxy statement regarding the Merger that will be filed by Ardea with the SEC.