Jobs: Pages

Laboratoriumtechnoloog Cytokine Receptor Lab

Veerle Quivreux — Fri, 25 May 2012 07:40:44 GMT

Het Cytokine Receptor Lab (CRL) maakt deel uit van het VIB Departement Medisch Proteïne Onderzoek en is gevestigd op de Rommelaere campus van de Universiteit Gent. Het CRL wordt geleid door Prof. Jan Tavernier en bestaat uit een 30-tal medewerkers (www.crl-mappit.be).
Een belangrijk onderzoeksdomein van het CRL is het ontwikkelen van nieuwe technologieën (o.a. MAPPIT en KISS) voor de identificatie en analyse van eiwit-eiwit en chemische molecule-eiwit interacties. Voor de ondersteuning van een aantal projecten in deze context is het CRL op zoek naar een enthousiaste laboratoriumtechnoloog.
Onder de supervisie van een postdoctoraal onderzoeker en in een team van ervaren laboratoriumtechnologen zal de geselecteerde kandidaat betrokken worden bij uiteenlopende onderdelen van deze projecten. Technieken die daarbij zullen toegepast worden zijn o.a. recombinant DNA technologie (PCR, plasmied constructie, DNA zuivering,…), eiwit technieken (Western blot,…) en celcultuurtechnieken (transfecties, FACS analyse, luciferase rapporteertesten,…).

Wij bieden:
• een interessante job in een dynamisch, jong en internationaal onderzoeksteam
• een contract voor 2 jaar met mogelijkheid tot verlenging
• een concurrentieel salaris

Technical support

Gent

Stuur je CV en motivatiebrief naar Jan Tavernier.
Voor meer informatie omtrent deze job kan je eveneens terecht bij Jan Tavernier (09/264 93 02)

VIB Dept. of Medical Protein Research - UGent
A. Baertsoenkaai 3
9000 Gent

VIB international postdoc program in integrative biology

Veerle Quivreux — Fri, 11 May 2012 11:50:01 GMT

VIB offers international fellowships to integrative biology postdocs who have advanced skills in omics technologies.

The omics@vib postdoc program offers a highly stimulating and multicultural environment. Embedded in excellent research groups, you will be working on breakthrough science, with access to cutting-edge technologies, three years secured funding and personal career assistance.

For the current omics@vib call, VIB provides 14 positions for integrative biology postdocs. Many VIB laboratories are suggesting an integrative biology topic for this program as indicated in the list below. You are free to select the topic of your own choice from the list and to design a 3 years postdoctoral project addressing this topic. More information on the laboratory of your choice as well as on the contact information is available through the links provided below.
Please contact the VIB group leader in charge of this topic before submitting your final applications.

Download the project overview in pdf
• Cancer
• Neurobiology
• Immunity/infection/inflammation
• Plant research
• Yeast research
• Bioinformatics

Postdocs

Antwerpen-Brussel-Gent-Leuven

June 2013 (the latest)

Please follow carefully the different steps during the preparation stage and final submission stage of your project application. Use English during all stages of this application.

Research position in Bio-informatics

Veerle Quivreux — Fri, 27 Apr 2012 09:11:58 GMT

In the Laboratory of Translational Genetics located in Leuven, we are offering a research position in bioinformatics to assist with the analysis of next generation sequencing data. Ideally, the holder of the position will be scientifically coordinating one or two research projects as a leading scientist and for this, will be able to rely on available data analysis pipelines and IT infrastructure. Additionally, he/she should be willing to participate in a number of collaborative projects within the Laboratory of Translational Genetics by performing advanced bio-informatics consulting and data analysis.

Who should apply for this job?
“If you are fascinated by computer science and have an extra-ordinary curiosity in biology and medicine, if you are driven by a wish to make a difference, if you enjoy and foster team work, if you consider yourself a “bridge” in your social network, if you are not phased by the unknown, willing to push the limits and ready to tackle a challenge, then this job could be just right for you.

Context:
Research in the Laboratory for Translational Genetics aims to unravel the genetic predisposition to cancer and annotate somatic changes in solid tumors with the ultimate aim to discover and functionally validate genetic biomarkers for cancer therapies. To this extend, state-of-the-art high throughput technologies are being used, including large-scale next-generation sequencing of DNA and RNA samples. One of the most exciting ongoing projects concerns the analysis of whole-genome sequencing data of tumor samples. Additionally, a number of projects involve the analysis of ChiPSeq data to characterize epigenetic modifications of (tumor) genomes and based on these data identify novel transcriptional regulatory networks. A key aspect in each of these projects is the use of specialized bio-informatics for primary data analyses (sequence assembly, mapping of deletions, amplifications, tandem duplications, invertions and interchromosomal rearrangements, etc), the development of novel algorithms for specific research questions, data interpretation (prioritization of identified genetic variants through data fusion, advanced pathway analyses and the application of advanced modeling approaches to predict disease-relevant characteristics). Additionally, each of these projects also involves the functional validation of the genetic/bio-informatic findings in models organisms using standard molecular biology and functional genomic tools.

We offer a dynamic working environment at the VIB-VRC located in Leuven, a competitive remuneration package, the opportunity to contribute to ambitious research projects from a young and motivated team and the possibility to be at the start of a scientifically cutting-edge and socially relevant project. To meet the increasing demands of performing multidisciplinary research, VRC offers Core facilities including Imaging, Molecular Biology, Proteomics, Histology, Aquatic facility (zebrafish & tadpoles), Mouse facility, etc. Specifically, for the current position, access to next-generation sequencing is enabled through the Genomics Core Facility (HiSEQ2000, Illumina iSCAN are operational) and the IT Infrastructure Unit (highcapacity computing clusters and data storage). Qualified senior candidates will have the possibility to mentor junior scientists and technicians, and work
semi-independently.

Starting date: as soon as possible

Bio IT

Leuven

To find out more about the project, the scientific challenge and the training opportunities, contact Diether Lambrechts who is heading the Laboratory of Translational Genetics.

Please send a complete CV, a list of publications, a summary of past research and the contact information of 2 or 3 referees. Top-ranked candidates will be invited for an interview in Leuven.
Applications should be submitted to evelien.verdrengh@vib-kuleuven.be

VESALIUS RESEARCH CENTER
VIB-KU Leuven
Campus Gasthuisberg O&N4
Herestraat 49 – box 912
3000 Leuven
www.vrc-lab.be

Personal Assistant

Veerle Quivreux — Mon, 02 Apr 2012 07:27:02 GMT

Prof. Claudia Bagni, head of the Laboratory for Molecular Neurobiology, Center for the Biology of Disease, is looking for a Personal Assistant to support herself and her team of international scientists (www.med.kuleuven.be/cme).
The laboratory works on the most frequent form of mental retardation : the Fragile X Syndrome as well as on other forms of intellectual disabilities. The laboratory is an internationally recognized team of scientists and trains PhD Students and Postdoctoral fellows in their scientific work.
The laboratory is located in a brand new building, overlooking the town of Leuven and forms part of the Faculty of Medicine of the Catholic University of Leuven.
The PA will work intensively with Prof. Bagni and support the lab team. Being the first point of contact in most cases, good communications skills and discretion will be vital in this role.

Function Description
-You will be the administrative right hand for the head of the laboratory and the main point of contact for the lab members.
-You will take instructions provided by the laboratory head and complete required tasks; screen and handle telephone calls and manage enquiries; manage post, emails and faxes, issuing responses where possible; act as a main point of contact; organize diaries and book appointments; assist laboratory head with meetings and arrange logistics, such as travel and accommodation; take minutes at lab meetings; produce letters or reports on the professor’s behalf; oversee office procedures
-You will oversee some financial aspects including handling the purchase orders for lab materials
-You will perform other related duties as required.

Offer
- A varied position within a dynamic international academic environment, where you will be able to develop your skills;
- A part-time contract (60 to 80%) with a trial period of 6 months - working hours from Monday to Friday;
- A competitive salary package;
- The offices are located in a new building on Campus Gasthuisberg, Leuven

Start date: as soon as possible.

Administration

Leuven

Please send your C.V. and motivation letter (in English) together with two references to: Diane.Casteels@cme.vib-kuleuven.be

VIB Center for the Biology of Disease, KU Leuven
Onderwijs en Navorsing 4
Campus Gasthuisberg
Herestraat 49, box 602
3000 LEUVEN
BELGIUM

Communicatie Expert Groene Biotechnologie

Veerle Quivreux — Thu, 29 Mar 2012 11:31:48 GMT

- Als expert wetenschapscommunicatie werk je mee aan wetenschappelijk gefundeerde en genuanceerde achtergrondinformatie over groene biotechnologie.
- Op basis van achtergronden die je wereldwijd gaat zoeken schrijf je teksten en maak je achtergronddossiers met de bedoeling groene biotechnologie op een gefundeerde manier uit te leggen aan het grote publiek
- Je schrijft persartikelen betreffende de vindingen van VIB plantenbiotechnologen
- Je neemt actief deel aan debatten, je geeft lezingen en je reageert gevat op de kritiek op groene biotech
- Je werkt samen met de communicatie experts van VIB en bouwt tegelijkertijd een goede relatie uit met de wetenschappers in het vakdomein.

Wij bieden:
Als communicatie expert kom je in contact met een zeer divers publiek gaande van wetenschappers tot maatschappelijke actoren en overheden. Je werkt autonoom, maar je kan rekenen op de ervaring en expertise van het vib communicatie en regulatory team. We bieden je tevens een salarispakket aangepast aan je ervaring en achtergrond . Je werkt in een vooraanstaand wetenschappelijk instituut met wereldfaam.

Staff positions Headquarters

Gent

Bezorg je sollicitatiebrief met omstandige motivatie en je CV naar jobs@vib.be voor eind april 2012.
Voor meer informatie kan je terecht bij marijke.lein@vib.be of op 09/244 66 11

VIB Headquarters
Rijvisschestraat 120
9052 Gent
Belgium

Office Manager - Secretary

Veerle Quivreux — Thu, 15 Mar 2012 12:38:04 GMT

VIB (Vlaams Instituut voor Biotechnologie) is a life sciences research institute in Flanders, Belgium, funded by the Flemish government. With more than 1400 scientists and supporting staff from over 60 countries in 8 departments, the institute performs basic research into the molecular foundations of life, with particular focus on translating basic scientific results into pharmaceutical, agricultural and industrial applications.

The VIB Department of Structural Biology is located at the Vrije Universiteit Brussels (VUB) campus and operates in close partnership with the university. The department has about 100 people in 10 research groups pursuing research in molecular structural biology. The department recently hired a new director, Peter Tompa, who is seeking a secretary to assist him in the daily management of the department.

Position Summary

The office manager will provide managerial and secretarial support to the director, which will include, but not be limited to: manage daily administrative and organizational activities of the department; follow financial and ordering activities; assist in the preparation of department reports; prepare group-leader meeting material and minutes; maintain a variety of databases on department issues, such as equipment supervision; assist the director in daily correspondence, electronic scheduling and traveling to meetings.

Terms

• Full-time position in the initial phase, with possibility to reduce the working time to 70 or 80 % at a later moment.
• Competitive salary and related benefits based on previous experience and competencies.
• Initial contract for 1 year, extendable with indefinite time contract
• Flexible starting date.

Administration

Brussel

Interested candidates should send their CV, contact details and references to Marijke Lein, HR director at VIB, via jobs@vib.be. Informal inquiries can also be sent to this address. First selection round will be held at VIB Headquarters in Gent, followed by further interviews in Brussels.
VIB is an equal opportunity employer. The position is open to all qualified applicants.

Software - Web developer

Veerle Quivreux — Tue, 06 Mar 2012 13:27:40 GMT

Het Departement voor Planten Systeembiologie, VIB, Universiteit Gent (www.psb.ugent.be) is een internationaal gerenommeerd, dynamisch laboratorium dat moleculaire genetica, genoomanalyse en bioinformatica combineert om ontwikkelingsbiologische processen te ontrafelen. Verschillende onderzoeksgroepen in bioinformatica ontwikkelen nieuwe software tools voor de integratie van grootschalige datasets, vergelijkende genoomanalyse en de constructie van regulatorische netwerken. Hiervoor is een extensieve computationele infrastructuur voorhanden. Om de synergie tussen experimenteel onderzoek en bioinformatica binnen PSB te versterken en het gebruik van bioinformatica methoden door experimentele biologen te ondersteunen zoekt PSB een Software - Web Developer.

Functiebeschrijving:
• Project-gebaseerde ontwikkeling, implementatie en integratie van bioinformatica software tools
• Ontwikkeling en beheer van Galaxy workflows. Galaxy is een open, web-gebaseerd platform, geschreven in Python (http://galaxy.psu.edu/). Dit gebruiksvriendelijke systeem zal beschikbaar gesteld worden aan het departement om een reproduceerbare en transparante computationele analyse van biologische data uit te voeren.
• Ontwikkeling van software en/of webapplicaties en de implementatie van software uitbreidingen om toegankelijkheid en gebruiksvriendelijkheid te verbeteren (via de ontwikkelinge van user interfaces, visualisatie, automatisering, etc.)
• Integratie van computationele tools (vaak in verschillende programmeertalen)

Aanbod:
• Start datum: zo snel mogelijk
• Contract: beperkte duur
• Duur: 2 jaar, mogelijkheid tot verlenging
• Een uitdagende en stimulerende werkomgeving, waar de nieuwste IT technologieën en innovaties geïmplementeerd worden

Gent

Als je de nodige vaardigheden hebt en graag wil appliceren op deze vacature, gelieve een motivatiebrief, CV en een lijst van referenten (naam, email, adres, tel) via email naar Nathalie Vanden Hautte (nathalie.vandenhautte@psb.vib-ugent.be) te sturen. Gelieve de referentie “PSB_DEV” in je applicatie te vermelden. Applicaties worden geëvalueerd tot de positie ingevuld is.

VIB Department of Plant Systems Biology, UGent
VIB Research Building FSVM
Technologiepark 927
9052 GENT
BELGIUM

Ph.D. Scholarship

Veerle Quivreux — Fri, 02 Mar 2012 14:00:15 GMT

A 4-year FWO PhD-position is available at the Brussels Center for Redox Biology (http://redox.vub.ac.be) in the Redox Biology lab of Joris Messens at the VIB (http://www.vib.be/en/research/scientists/Pages/Joris-Messens-Lab.aspx) for research on the one-cysteine peroxiredoxin AhpE of Mycobacterium tuberculosis. The research project is a collaboration with the group of Madia Trujillo at Departamento de Bioquímica and Center for Free Radical and Biomedical Research, Facultad de Medicina, Universidad de la República in Uruguay and the quantum chemistry group of Frank De Proft at the Vrije Universiteit Brussel (VUB).

We offer a fellowship for four years in a Centre of excellence, backed by first class research facilities and training in our multidisciplinary, international scientific community. VIB scientists work at the frontlines of molecular biology, cell biology, developmental biology, structural biology, plant systems biology, genetics, biochemistry and microbiology. VIB is a life sciences research Centre in Flanders, Belgium, in the heart of Europe. 

Ph.D.

Brussel

Interested candidates should send their CV together with a scan of a transcript of marks of your academic record and the coordinates of 2 reference persons to Joris Messens (joris.messens@vib-vub.be).

VIB Department of Structural Biology, Vrije Universiteit Brussel
Building E
Pleinlaan 2
1050 BRUSSEL
BELGIUM

Ph.D. or Postdoctoral scientist – computational biology

Veerle Quivreux — Wed, 22 Feb 2012 07:58:06 GMT

We are looking for an ambitious PhD student or postdoctoral fellow with an excellent background in bioinformatics-genomics. The candidate will be working at the interface between the laboratories of prof. Bart De Strooper (VIB Center for the Biology of Disease and Dept. for Human Genetics KU Leuven) and prof. Thierry Voet (Dept. for Human Genetics KU Leuven).

The candidate will be a key player in a project that is focused on the dissection of genetic heterogeneity in human brain biopsies to the single neuron level. In order to chart the full spectrum of genetic variants mosaic in a human brain, we will apply novel state-of-the-art methods based on deep-sequencing of bulk DNA as well as single-cell genome sequencing. With this approach we aim to find novel causes of Alzheimer’s disease.

Background:
We have established expertise in the fields of neuroscience, next-generation sequencing data analyses, including single-cell genomics. Immediate access to a Genomics core facility harboring a Roche 454 and Illumina HiSeq2000 sequencer is available, and we have strong collaborative links with a large genome center, the Wellcome Trust Sanger Institute in Cambridge (UK). Furthermore, we are embedded in SymBioSys which is a consortium of computational biologists and geneticists at the University of Leuven (Belgium) focusing on the development of innovative bioinformatics methods to analyze next-generation sequencing data and to address key biological questions. The consortium has delivered multiple biological breakthroughs.

We offer a competitive package and a fun, dynamic environment with a top-notch consortium of young leading scientists in bioinformatics, human genetics, and neuroscience research.
The VIB Center for the Biology of Disease is embedded in the department of Human Genetics of the University of Leuven. It is an international research institute in the center of Europe (close to Brussels and fast train connections to Paris, London, Cologne and Amsterdam), with access to high end technology, core facilities, technical support and a brand new research building. Good knowledge of English is sufficient for all communications both within and outside of the institute.

The starting date is as early as practical.

Related publications
Konings P et al. Microarray analysis of copy number variation in single cells. Nature Protocols, 2012;7(2):281-310.

Benilova I, Karran E, De Strooper B. The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes. Nat Neurosci. 2012 Jan 29. doi: 10.1038/nn.3028. [Epub ahead of print] PubMed PMID: 22286176.

De Strooper B. Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process. Physiol Rev. 2010 Apr;90(2):465-94. Review. PubMed PMID: 20393191.

Van Loo P et al. Allele-specific copy number analysis of tumors. Proc Natl Acad Sci U S A. 2010;107(39):16910-5.

Vanneste E et al. Chromosome instability is common in human cleavage-stage embryos. Nature Medicine 2009;15(5):577-83.

Postdocs

Leuven

Please send in PDF:
(1) a motivation letter
(2) CV including education (with Grade Point Average, class rank, honors, etc.), research experience and bibliography
(3) a one-page research statement that demonstrates your interest in this type of research and motivation
(4) three references (incl. email and phone)
to Mrs Hilde Govaert (hilde.govaert@cme.vib-kuleuven.be), PA to prof.dr. Bart De Strooper.

Bioinformaticus

Veerle Quivreux — Sun, 19 Feb 2012 13:23:29 GMT

Het VIB Departement voor Moleculaire Genetica (VIB DMG www.molgen.ua.ac.be) wenst over te gaan tot de aanwerving in haar centrale service faciliteiten van een voltijdse Bioinformaticus (m/v)

Het VIB DMG is één van de acht onderzoekdepartementen van het VIB instituut (www.vib.be). In VIB DMG zijn een 100-tal onderzoekers werkzaam in het domein van de complexe neurologische zenuwziekten bij mens. VIB DMG beschikt over centrale service faciliteiten voor genetische, genomische en cellulaire analyses.

De kandidaat (m/v) is houder van een universitair diploma van master of doctor in de wetenschappen, biomedische wetenschappen of (bio)informatica of beschikt over gelijkgestelde expertise. De functie omvat ondersteunende activiteiten in het kader van de diensten aangeboden door de centrale service faciliteiten. De kandidaat zal instaan voor de verwerking van sequencing en next-generation-sequencing data, en het onderhoud en de ontwikkeling van de genetische databanken.

Voor deze functie wordt afhankelijk van de vooropleiding en/of relevante ervaring het salaris berekend op basis van de barema’s 7.1 (master) of 9.1 (doctoraat) welke gehanteerd worden aan de universiteit. Nuttige jaren ervaring worden in rekening gebracht. Voor kandidaten met ervaring voorzien wij een aanstelling met een contract van onbepaalde duur en een proefperiode van 6 maanden.

Bio IT

Antwerpen

Schriftelijke kandidaturen voorzien van een uitgebreid Curriculum Vitae worden verwacht per e-mail of fax tot 30 april 2012.

Secretariaat VIB DMG

Mevr. Giséle Smeyers
Fax. 03 265 1112
E-Mail gisele.smeyers@molgen.vib-ua.be

VIB Departement voor Moleculaire Genetica
Universiteit Antwerpen - CDE
Parking P4, Gebouw V
Universiteitsplein 1
B-2610 Antwerpen

Data Manager

Veerle Quivreux — Sun, 19 Feb 2012 13:19:19 GMT

Het VIB Departement voor Moleculaire Genetica (VIB DMG www.molgen.ua.ac.be) wenst over te gaan tot de aanwerving in haar centrale service faciliteiten van een voltijdse Data Manager (m/v)

Het VIB DMG is één van de acht onderzoekdepartementen van het VIB instituut (www.vib.be). In VIB DMG zijn een 100-tal onderzoekers werkzaam in het domein van de complexe neurologische zenuwziekten bij mens. VIB DMG beschikt over centrale service faciliteiten voor genetische, genomische en cellulaire analyses.

De kandidaat (m/v) is houder van een diploma van master in Informatica uitgereikt door een hogeschool of door een universiteit of beschikt over gelijkgestelde professionele expertise. De functie omvat ondersteunende activiteiten in de centrale service faciliteit en in het VIB DMG departement. De kandidaat staat in voor de goede werking van de LIMS en ELN systemen en het onderhoud van de databanken. Hij/zij werkt mee aan het stroomlijnen en uitvoeren van de genetische pijplijnen met toepassingen in het wetenschappelijke onderzoek en in klinische genetische testen van erfelijke ziekten.

Voor deze functie wordt afhankelijk van de vooropleiding en relevante ervaring, het salaris berekend op basis van het barema 6.1 of 7.1 dat gehanteerd wordt door de Universiteit van Antwerpen. Nuttige jaren van professionele ervaring worden in rekening gebracht. Voor ervaren kandidaten voorzien wij een aanstelling met een contract van onbepaalde duur en een proefperiode van 6 maanden.

Antwerpen

Onderzoekstechnoloog

Veerle Quivreux — Tue, 14 Feb 2012 08:50:15 GMT

Het VIB DMG is één van de acht onderzoekdepartementen van het VIB instituut (www.vib.be). In VIB DMG zijn een 100-tal onderzoekers werkzaam in het domein van de complexe neurologische zenuwziekten bij mens. VIB DMG beschikt over centrale service faciliteiten voor genetische, genomische en cellulaire analyses.

Functie

De kandidaat (m/v) is houder van een diploma van master in Biochemie/Biotechnologie, uitgereikt door een hogeschool of door een universiteit of beschikt over gelijkgestelde expertise. De functie omvat ondersteunende activiteiten in de centrale service faciliteit in het kader van het ontwikkelen van applicaties van toepassing in het wetenschappelijke onderzoek en in klinische genetische testen van erfelijke ziekten.

De kandidaat heeft een ruime kennis van de genetica en genomica en ervaring met genetische en recombinant DNA technieken zoals mutatiedetectie in genomisch DNA (high-throughput sequentiebepaling), dosage detectie van deleties/duplicaties (kwantitatieve PCR), functionele genomica zoals epigenetica en transcriptomica, cloneren van DNA. Kennis van de technieken van de next-generation-sequencing en ervaring met het gebruik van computer software voor de analyse van genetische en genomische data strekken tot aanbeveling.

Voor deze functie in de centrale service faciliteit wordt het salaris berekend afhankelijk van de vooropleiding en relevante ervaring op basis van het barema 6.1 of 7.1 dat gehanteerd wordt aan de universiteit. Nuttige jaren ervaring worden in rekening gebracht worden. Voor kandidaten met ervaring voorzien wij een aanstelling met een contract van onbepaalde duur en een proefperiode van 6 maanden.

Technical support

Antwerpen

Administratief Medewerker

Veerle Quivreux — Tue, 14 Feb 2012 08:46:36 GMT

Het VIB DMG is één van de acht onderzoekdepartementen van het VIB instituut (www.vib.be), verbonden aan de Universiteit van Antwerpen. In VIB DMG zijn een 100-tal onderzoekers werkzaam in het domein van de complexe neurologische zenuwziekten bij mens.

Functie

De kandidaat (m/v) is houder van een diploma van het Technisch Secundair Onderwijs – Studiegebied Handel: Boekhouden-Informatica of beschikt over gelijkgestelde beroepservaring.

De kandidaat wordt ingeschakeld in het algemene secretariaatswerk in de centrale administratie van het VIB DMG onderzoekdepartement. De taken zijn ondersteunend en omvatten ondermeer registratie en klassement van documenten, het invoeren van data in en het onderhoud van elektronische databanken, het ophalen en het verdelen van post en het klaarmaken van koerier zendingen, ontvangen en verwerken in de stock database van leveringen, het printen, inbinden en verdelen van documenten, het beheer van vergaderlokalen etc.

De kandidaat heeft kennis van de werking van een secretariaat, basiskennis van boekhouden en heeft ervaring met de computer software programma’s van MS Office en in het bijzonder Word en Excel. Ervaring in administratief werk, het beheren van databases en kennis van Frans en Engels zijn pluspunten.

Voor deze functie in de centrale administratie wordt het salaris berekend op basis van het barema 3.1 dat gehanteerd wordt aan de universiteit. Nuttige jaren ervaring worden in rekening gebracht worden. Voor kandidaten met ervaring voorzien wij een aanstelling met een contract van onbepaalde duur en een proefperiode van 6 maanden.

Administration

Antwerpen

Schriftelijke kandidaturen voorzien van een foto en een uitgebreid Curriculum Vitae worden verwacht per e-mail of fax tot 30 april 2012.

Secretariaat VIB DMG

Mevr. Giséle Smeyers
Fax. 03 265 1112
E-Mail gisele.smeyers@molgen.vib-ua.be

VIB Departement voor Moleculaire Genetica
Universiteit Antwerpen - CDE
Parking P4, Gebouw V
Universiteitsplein 1
B-2610 Antwerpen

Laboratoriumtechnologen

Veerle Quivreux — Tue, 14 Feb 2012 08:40:52 GMT

Het VIB DMG is één van de acht onderzoekdepartementen van het VIB instituut (www.vib.be). In VIB DMG zijn een 100-tal onderzoekers werkzaam in het domein van de complexe neurologische ziekten bij mens. VIB DMG beschikt over centrale service faciliteiten voor genetische, genomische en cellulaire analyses.

Functie

De kandidaat (m/v) is houder van een diploma van professionele bachelor in Biochemie en/of Biotechnologie, uitgereikt door een hogeschool of beschikt over gelijkgestelde expertise. De functie omvat ondersteunende activiteiten in het kader van het wetenschappelijke onderzoek in VIB DMG en/of services aan derden zoals Sanger DNA sequentieanalyses of klinische genetische testen in de diagnostiek van erfelijke ziekten.

De 3 laboratorium technologen worden tewerkgesteld in de centrale service faciliteit die ondersteunend laboratorium en technologisch werk verricht voor de onderzoekers in VIB DMG of derde partijen.

Kennis van de genetica en van volgende genetische technieken is wenselijk: PCR, mutatiedetectie in genomisch DNA (high-throughput sequentiebepaling), genotyperingen of SNP detectie (massArray), analyse van microsatelliet merkers of STR merkers (Genescan), dosage detectie van deleties/duplicaties (kwantitatieve PCR) en het gebruik van software voor de analyse van genetische data. Afhankelijk van de functie binnen de centrale service faciliteit is het wenselijk om ervaring te hebben met DNA extracties, het cultiveren van cellen, biochemie en/of recombinant technologie.

Voor deze functie in de centrale service faciliteit wordt het salaris berekend op basis van het barema 4.1 dat gehanteerd wordt aan de universiteit. Nuttige jaren ervaring kunnen in rekening gebracht worden. Een eerste aanstelling gebeurt met een contract van bepaalde duur en een proefperiode van 6 maanden.

Technical support

Antwerpen

Ph.D. Student EMT- stem cells and inflammation - a malignant cocktail for cancer

Veerle Quivreux — Thu, 02 Feb 2012 07:27:28 GMT

We are looking for a highly motivated student to start a PhD research project focusing on the interactions of malignant cancer cells with the innate and adaptive immune systems. In particular, this project seeks to gain insight into the molecular mechanisms of how cancer cells undergoing epithelial mesenchymal transition (EMT) cross talk with the tissue micro environment to drive the switch from a non-invasive lesion to metastasis. The ultimate goal is to take advantage of genetic studies in cells and EMT in vivo models to define new putative targets for cancer diagnosis and therapy. You will be working together with one other PhD student, one technician, and one senior postdoc in the unit Molecular and Cellular Oncology headed by Prof. G. Berx. The work will make use of cutting edge methods, including recombinant DNA technology, cell culture, transfection of cells, analysis of gene and protein expression, RNAi technology, stem and cancer stem cell isolation, use of transgenic and knockout mice, and flow cytometry. The research unit consists of enthusiastic people working in the field of EMT and cancer progression.

2 years contract with 2 years extension upon positive evaluation
Starting date: immediately

Ph.D.

Gent

Send applications (English) with CV (including names of two referees) to Geert Berx. For more information contact: Prof. Dr. Geert Berx (+32.9.33 13660) or Dr. Geertrui Denecker (+32.9.3313662) or Dr. Bram De Craene (+32. 9.33 13663)

VIB Department for Molecular Biomedical Research, UGent
VIB Research Building FSVM
Technologiepark 927
9052 GENT
BELGIUM

Lab Technician Membrane Trafficking

Veerle Quivreux — Tue, 31 Jan 2012 12:04:28 GMT

Prof. Wim Annaert (laboratory for Membrane Trafficking) has recently developed in collaboration with IMEC (Leuven) superparamagnetic nanoparticles that enable the isolation of selective membrane compartments from any type of cell. Due to a rapidly increasing demand for such nanoparticles, and this in the light of new collaborative studies in the fields of neurodegeneration, cancer and immunology, the group is seeking urgently a lab technician with a chemical background for maintaining and expanding the synthesis and production of different types of nanoparticles. The applicant will be involved in activities both at IMEC (synthesis) as well as at Gasthuisberg (applications).

Technical support

Leuven

Please send a motivation letter and your CV in English (mentioning job code ATP_WiAn_0112) to Diane Casteels
For additional information regarding this job please contact Prof. Wim Annaert

VIB Center for the Biology of Disease, K.U.Leuven
Onderwijs en Navorsing 4
Campus Gasthuisberg
Herestraat 49, box 602
3000 LEUVEN
BELGIUM

Predoctoral Researcher Position - Identification of novel plant growth promoting proteins that are subject to degradation by the Anaphase-Promoting Complex (APC/C)

Veerle Quivreux — Tue, 31 Jan 2012 11:56:43 GMT

The Department of Plant Systems Biology, VIB, University Ghent is an internationally renowned and dynamic research institute that employs molecular genetics, genomics and bioinformatics to unravel developmental processes in plants.
Crop productivity becomes increasingly important to sustain food, feed and bio-energy consumption. As cell division is pivotal for plant growth, understanding how cell cycle progression is controlled may offer ways to increase the yield of important crop species. Unidirectional and irreversible progression through the cell cycle is mediated through the selective proteolytic control of both positive and negative regulators of the cell cycle. A major protein complex dedicated to the basic cell cycle control is the Anaphase-Promoting Complex/Cyclosome (APC/C), targeting proteins for destruction. Activity of the APC/C links to the timing of cell differentiation and growth. Recently, we have identified key regulators of the APC/C (Heyman et al., 2011; Eloy et al., 2011), however how this complex controls growth and development remains elusive. The proposed project aims to fill this knowledge gap through the identification of growth related APC/C targets. To meet this objective, two independent strategies will be followed. A first strategy involves the in planta identification of suppressor genes that abolish the growth-inhibiting effect of an APC/C mutant that shows a retarded growth. The second strategy relies on a differential proteomic screen. Potential APC/C targets will be analyzed for their growth promoting effects, first in Arabidopsis thaliana, and subsequently in maize.

References

Eloy NB, de Freitas Lima M, Van Damme D, Vanhaeren H, Gonzalez N, De Milde L, Hemerly AS, Beemster GT, Inzé D, Ferreira PC. (2011) The APC/C subunit 10 plays an essential role in cell proliferation during leaf development. Plant J. 68: 351-363.

Heyman J, Van den Daele H, De Wit K, Boudolf V, Berckmans B, Verkest A, Kamei CL, De Jaeger G, Koncz C, De Veylder L. (2011) Arabidopsis ULTRAVIOLET-B-INSENSITIVE4 maintains cell division activity by temporal inhibition of the Anaphase-Promoting Complex/Cyclosome. Plant Cell, in press.

The position remains open until a suitable candidate has been recruited.

Ph.D.

Gent

Please respond by e-mail, including your letter of motivation to lieven.deveylder@psb.vib-ugent.be

VIB Department of Plant Systems Biology, UGent
VIB Research Building FSVM
Technologiepark 927
9052 GENT
BELGIUM

Post-doctoral position DYT1 dystonia pathogenesis

Veerle Quivreux — Fri, 13 Jan 2012 07:31:05 GMT

We are searching for a post-doctoral researcher to work on the molecular cell biology of torsinA dysfunction in DYT1 dystonia. The project is in the Laboratory of Rose Goodchild in the VIB Centre for the Biology of Disease at KU Leuven. This is a new research team, but with many years of experience in dystonia research.

Primary dystonia is a neurological disease characterized by abnormal, involuntary twisting movements. DYT1 dystonia is the most common familial primary dystonia and is caused by a three-base pair deletion that removes a glutamic acid residue (ΔE) from torsinA. We have evidence that the nuclear envelope subdomain of the endoplasmic reticulum is a key site of normal torsinA function and ΔE-torsinA dysfunction. This project will study the normal function of torsinA, how torsinA and the nuclear envelope is important for developing neurons, and the pathogenic consequences of ΔE-torsinA mislocalization to the neuronal nuclear envelope. The project will use a wide variety of techniques including biochemistry, cell models, and assessment of torsinA-null and torsinA-ΔE mouse lines. Additionally, the Centre for the Biology of Disease has strengths in many areas and collaborative approaches are possible and will be emphasized as the project matures.

References:
Jungwirth, M.T., et al The nuclear envelope localization of DYT1 dystonia torsinA-ΔE requires the SUN1 LINC complex component. BMC Cell Biol. 2011. 12:24.
Jungwirth M.T., et al. Relative tissue expression of homologous torsins can explain the neuronal specific importance of DYT1 dystonia-associated torsinA. Human Molecular Genetics 2010. 19(5):888-900.
Goodchild, R.E., et al. Loss of the Dystonia-Associated Protein TorsinA Selectively Disrupts the Neuronal Nuclear Envelope. Neuron 2005. 923-932.
Goodchild & Dauer. The disease associated AAA+ protein, torsinA, interacts with homologous proteins in the nuclear envelope and endoplasmic reticulum lumen. Journal of Cell Biology. 2005 168(6): 855-862.
Goodchild & Dauer. Mislocalization to the Nuclear Envelope: A Novel Effect of the Dystonia-Causing TorsinA Mutation. PNAS. 2004 20;101(3):847-852.

The Centre for the Biology of Disease is located in a new scientific building on the main biomedical campus of KU Leuven. Leuven is a dynamic student town located close to Brussels and Brussels International Airport, and with good road and rail links all over Europe.

Postdocs

Leuven

How to apply? Send your application including of a letter of motivation or personal statement, CV, and contact information for three references, to Rose Goodchild

VIB Center for the Biology of Disease, K.U.Leuven
Onderwijs en Navorsing 4
Campus Gasthuisberg
Herestraat 49, box 602
3000 LEUVEN
BELGIUM

Ph.D. Position

Veerle Quivreux — Fri, 13 Jan 2012 07:24:01 GMT

At the VIB department for Structural Biology (VIB - Vrije Universiteit Brussel), we are looking for a highly motivated PhD student interested in biochemical and structural studies on enzymes involved in bacterial persistence.

The biological focus of the VIB Department of Structural Biology is to explore biomolecular interaction networks in order to understand protein function in health and disease. Accordingly, these new insights will be exploited for the design of medically and/or industrially relevant molecules and products. Our multidisciplinary team of about 70 researchers is housed in new laboratory facilities and combines extensive expertise in structural biology (X-ray crystallography, NMR, EM and atomic force microscopy), biophysics, enzymology and molecular biology.

Project description:
The research topic deals with the structural and functional characterization of newly identified enzymes involved in the acquisition of the persistence phenotype in the human pathogen P. aeruginosa. Persisters are highly multidrug-tolerant cells that constitute a small fraction of a population and are largely responsible for biofilm tolerance to antibiotics. Through collaboration with the group of Prof. J. Michiels (Centre of Microbial and Plant Genetics, KULeuven), we will combine the genetic analysis of persistence, with detailed biochemical, biophysical and structural in vitro studies, in order to contribute to a complete mechanistic understanding of the principles underlying persistence.

During your PhD you will be studying the functioning and regulation of these enzymes and their interaction partners, using an approach of X-ray crystallography, enzyme kinetics and different biophysical methods.

Start date
The position is available immediately.

Ph.D.

Brussel

Interested applicants should send 1) a statement of skills and research interests, 2) a curriculum vitae and 3) the names and contact information of 2-3 references to:

Wim Versées, PhD
Structural Biology Brussels
Vrije Universiteit Brussel
Pleinlaan 2
1050 Brussel
www.verseeslab.structuralbiology.be
http://www.vib.be/en/research/scientists/Pages/Jan-Steyaert-Lab.aspx

Group Leaders NERF

Veerle Quivreux — Mon, 09 Jan 2012 07:31:35 GMT

NERF is the new centre for Neuro-Electronics Research Flanders. It is a joint basic research initiative, set up by VIB, imec and KU Leuven to understand the function of brain circuits. At NERF basic neuroscientific questions are addressed through collaborative, interdisciplinary research, combining nanoelectronics with neurobiology. The center intends to push the boundaries of science, by zooming in on the functioning of neural circuits at an unprecedented level of detail. In the long run, NERF will generate new insights into the functional capabilities of the circuits of the mind as well as into research methodologies and technologies for medical applications, i.e. diagnostics and treatment of disorders of the central and peripheral nervous system (see www.NERF.be).

NERF is housed on the imec campus in Leuven, Belgium, where researchers work in cross-disciplinary teams, benefitting from imec’s state-of-the-art clean room infrastructure and a new 800 m² well equipped neuro-science lab, dedicated to NERF. NERF has already recruited 3 teams of top-notch researchers doing worldclass basic research in neural circuit analysis and is recruiting 2 additional groups. The focus is on unraveling the input and output signals of individual neurons, which underlie collective computations in neuronal circuits in the brain of living, behaving animals. Devices to do so will be developed in close collaboration with imec research teams on site. By 2014, NERF aims to expand its international team to about 50 excellent researchers, organized in 5 research groups with complementary interests and technical skills, each led by an independent group leader. A long term foundation of financial support is provided by the 3 founders and the Government of Flanders. NERF scientists will be able to work closely with a wide range of over 30 neuroscience research groups covering a wide range of expertise (such as neuronal communication, axon guidance, brain-computer interface, electrophysiology, …) and core and service facilities (such as genomics, transcriptomics, proteomics, imaging, electronic and mechanical workshops, animal housing…) already established at the 3 founding institutions.

You will investigate the functioning of the brain in a living animal. The focus is on studying information processing in neuronal circuits using experimental and computational methods (with particular emphasis on awake and behaving animals) or theoretical approaches. In close collaboration with imec research teams you will be involved in the design and development of ground breaking devices, beyond the current state-of-theart. You will be empowered by working closely together with a wide range of experts from the 3 founding institutions, providing the NERF labs with a unique competitive advantage.

As a NERF Group Leader, you will be responsible for:
• developing an innovative research program, fitting the mission and research objectives of NERF
• organizing and managing your own research group
• interacting with the other NERF research groups and the research community of imec, VIB and KU Leuven, active in the field.

The package offered will consist of:
• a competitive group leader salary
• a start-up package
• continuous funding of your own research group with 3 full time positions
• full access to local and international competitive grants
• dedicated lab space
• privileged access to the core facilities of VIB, imec and KU Leuven
• an exciting intellectual and research environment.

Senior scientific (managerial)

Leuven

Candidates who are interested in this position are asked to send a complete CV, publication list and 3 letters of reference to
anke.vannoten@nerf.be. Further information can be obtained from Gustaaf Borghs, NERF Coordinator +32 16 28 12 11 or Jo Bury,
Chair of the NERF Board +32 9 244 66 11.

Postdoctoral position in electrophysiology of Alzheimer’s Disease

Veerle Quivreux — Wed, 21 Dec 2011 12:57:29 GMT

γ-secretase is involved in Alzheimer's Disease (AD) since it produces the Amyloid-beta protein that aggregates in the amyloid plaques of AD patients (De Strooper, Neuron, 2003). Different γ-Secretase complexes exist that can regulate specific cognitive functions (Dejaegere al., PNAS, 2008; Serneels et al., Science, 2009). In addition to the production of Amyloid-beta, γ-Secretase controls other proteins that are important for neuronal function. Among them, we found APP, Notch and the schizophrenia risk genes Nrg1 and ErbB4 (Fazzari et al., Nature, 2010). However, the physiological role of γ-Secretase in the brain is still poorly understood. In this research project, we aim to determine the specific role of diverse γ-Secretase complexes in the maintenance of brain circuits.

The job will involve electrophysiological recordings in different mutant γ-secretase mice available in the lab in combination with selective genetic experiments at the cellular level using viral transduction to inactivate specific gamma-secretase complexes in different areas of the brain. There is ample opportunity to interact with a multidisciplinary and international team of dedicated scientists to unravel the molecular and cell biology role of the different γ-secretases.

We offer an excellent postdoctoral position in an international research institute in the center of Europe (close to Brussels and fast train connections to Paris, London, Cologne and Amsterdam), with access to high end technology, core facilities, technical support and a brand new research building. Good knowledge of English is sufficient for all communications both within and outside of the institute.

The starting date is flexible in the first half of 2012.

Postdocs

Leuven

Please send your CV and motivation letter to Hilde Govaert

VIB Center for the Biology of Disease, K.U.Leuven
Onderwijs en Navorsing 4
Campus Gasthuisberg
Herestraat 49, box 602
3000 LEUVEN
BELGIUM

Postdoctoral Position - Genetic Investigation of Astrocyte Function

Veerle Quivreux — Thu, 15 Dec 2011 09:54:57 GMT

The Laboratory of Glia Biology is a new group based at the VIB Center for the Biology of Disease. We are currently looking for a highly skilled postdoctoral scientist to join our team from the beginning of 2012.

Background:
Astrocytes are the most abundant cell type in the human brain and there is increasing evidence that these cells play an essential role in development, maintenance and function of the nervous system. However, the precise molecular mechanisms underlying these functions remain unknown.

Our lab has a particular interest in the pathway(s) controlling astrocyte-neuron communication. We have recently embarked on a long-term project to identify critical intracellular signaling pathways that control this process, using biochemical analysis of acutely isolated astrocytes. Ultimately, our goal is to assess the importance of identified pathways in vivo, through the production and analysis of novel transgenic mouse lines.

The Project:
Primarily, the successful candidate will be tasked with developing novel genetic tools that facilitate transgenic animal production. In particular, we are interested in the use of in utero electroporation and viral delivery techniques.

In addition, a successful applicant would have the possibility to participate in the subsequent analysis of the resulting mice. Methods to be used include in vivo imaging using 2-photon microscopy (through a thinned skull preparation), as well as electrophysiological recordings from brain slice preparations.

Postdocs

Leuven

Please send a covering letter and CV (including the contact details of three referees) to Matthew Holt

VIB Center for Biology of Disease, K.U.Leuven
Onderwijs en Navorsing 4
Campus Gasthuisberg
Herestraat 49, box 602
3000 LEUVEN
BELGIUM

Ph.D. Student - Biochemical studies of neurotransmitter release in Drosophila melanogaster

Veerle Quivreux — Thu, 15 Dec 2011 09:51:03 GMT

The Holt lab retains an interest in the mechanism of neurotransmitter release in the nervous system, and is seeking an exceptional Ph.D. student to join an on-going project that is being run in collaboration with Prof. Stephan Sigrist (Frei Universität, Berlin).

Background:
Neurons communicate with each other through the release of neurotransmitters, from the presynaptic terminal. Neurotransmitters are initially stored in small membranous organelles called synaptic vesicles. These vesicles are trafficked to the presynaptic plasma membrane where they fuse and release their contents.

To ensure precise control of the process, the presynaptic terminal possesses a complex network of interacting proteins. The protein Bruchpilot has been identified as central to the release process in Drosophila melanogaster. Bruchpilot is thought to be the main protein component of the so-called ‘T-bar’. The T-bar is an electron dense structure found at the release site. It is thought to operate by capturing vesicles from the cytoplasm and channelling them to release sites on the plasma membrane. Importantly, we have recently identified several mutations in a region of Bruchpilot that affect the binding of synaptic vesicles to this protein.

The Project:
In this project, we will use advanced biochemical techniques to investigate the precise nature of Bruchpilot-synaptic vesicle binding. These approaches will center predominantly on novel techniques that have been developed by the host laboratory for the fractionation and analysis of Drosophila neural tissue.

Following the identification of putative vesicle binding domains, the findings will then be validated in vivo using Drosophila mutants in combination with super-resolution imaging (STED and electron microscopy) and electrophysiology.

Ph.D.

Leuven

Please send a covering letter and CV (including the contact details of three referees) to Matthew Holt

VIB Center for the Biology of Disease, K.U.Leuven
Onderwijs en Navorsing 4
Campus Gasthuisberg
Herestraat 49, box 602
3000 LEUVEN
BELGIUM

Ph.D. Student Proteomics-based Characterization and Functional Analysis of Inflammatory Caspase Signaling

Veerle Quivreux — Fri, 09 Dec 2011 13:12:38 GMT

Inflammatory caspases are responsible for production of interleukin (IL)-1β and IL-18 upon their recruitment into inflammasomes. They also mediate the non-conventional secretion of danger signals and induce pyroptosis, a pro-inflammatory cell death program that removes infected immune cells and prevents intracellular replication of bacterial pathogens. On the other hand, inflammatory caspases may dampen immune responses.

To better understand the functions of inflammatory caspases, we are currently looking for a motivated Ph.D. student to work on the identification and functional characterization of inflammatory caspase substrates. The successful candidate will make use of positional proteomics technologies to determine and compare the optimal protein substrate recognition sequences of the inflammatory caspases-1, -11 and -12. In addition, the roles of identified substrates will be examined in several cellular and mouse models of inflammation and infection to understand inflammatory caspase signaling pathways under pathophysiological conditions.

The position is immediately available, and will be jointly supervised by Prof. Dr. Mo Lamkanfi and Prof. Dr. Kris Gevaert at the VIB/UGent Department of Medical Protein Research, which is located in the city center of Ghent.

Ph.D.

Gent

Interested candidates are encouraged to send their CV, along with a letter stating their interest and contact details of two references to Mohamed Lamkanfi. Informal enquiries can also be addressed to the same email address.

VIB Department of Medical Protein Research, UGent
Albert Baertsoenkaai 3
9000 GENT
BELGIUM

Postdoctoral Scientist Neuronal Communication

Veerle Quivreux — Thu, 08 Dec 2011 08:59:44 GMT

The VIB Center for Biology of Disease at the K.U.Leuven is a vibrant and international research centre where key issues relevant to major human health challenges are tackled. In the laboratory of neuronal communication we study the molecular mechanisms of synaptic transmission in health and disease and we use genetics as well as imaging and electrophysiology to study neuronal communication.

In collaboration with other team members, you will tackle research questions related to synaptic function and Parkinson’s disease. You will use genetic screening in fruit flies to identify novel components that modify synaptic transmission and Parkinson’s disease progression and you will be use electrophysiological and advanced imaging technology to follow activity in live neurons, including the neuromuscular system as well as dopaminergic neurons in the fly brain.

For more information, please visit http://verstreken.vib.be

We offer a renewable contract as a member of an ERC Starting Grant team, a competitive salary and benefits.
K.U.Leuven and VIB are equal opportunity employers.

Postdocs

Leuven

If you are interested and you are a motivated and interactive individual, please send your CV, a short letter of motivation and the names of 2 references to Patrik Verstreken.
International candidates are very strongly encouraged to apply.

VIB Center for Biology of Disease
Onderwijs en Navorsing 4
Campus Gasthuisberg
Herestraat 49, box 602
3000 LEUVEN
BELGIUM

Postdoctoral scientist in bioinformatics

Veerle Quivreux — Fri, 02 Dec 2011 13:38:35 GMT

The laboratory of Peter Tompa at the VIB Department of Structural Biology, Vrije Universiteit Brussel (Belgium) is seeking to hire a postdoctoral expert in bioinformatics.

Peter Tompa, a world expert on intrinsically disordered proteins (IDPs, Tompa 2002 TiBS 27: 527; Tompa 2011 Curr. Opin. Struct. Biol. 21: 419), recently moved to take the position of director of the department and started his lab to work on various projects related to IDPs. The major topics in the lab (cf. also http://www.vib.be/en/research/scientists/Pages/Peter-Tompa-Lab.aspx) will be:

1) Molecular biology of ID chaperones. 2) Structure-function relationship of very large (“oversized”) proteins. 3) Synthetic biology approaches to create artificial IDPs. 4) Bioinformatics analysis of IDPs, with particular focus on dual-coding regions in pathogens and eukaryotes, metagenomics and systems biology.

We are looking for a candidate for the postdoctoral position in this lab. The candidate is expected to conduct bioinformatics research in diverse fields, including strong synergy with the wet-lab projects of the lab. He/she is expected to be highly motivated and creative, showing the energy and determination to fit in a top laboratory in one of the fastest-developing areas of structural biology. The candidate will join a team of international researchers that investigate various aspects of structural disorder by combining theoretical, structural, biophysical, biochemical and cell-biological approaches. In addition to his own research projects, the candidate is also expected to supervise PhD students.

Terms
Fulltime contract for an initial period of 2 years
Competitive salary and benefits (health insurance, sport facilities, vacation days ...)
Starting date: as soon as possible

Bio IT

Brussel

Interested candidates should send their CV, a list of publications, a summary of past research, and contact details of two or three references to Peter Tompa.
Informal inquiries can also be sent to this address. Top-ranked candidates will be invited for an interview in Brussels, Belgium.

VIB Department of Structural Biology, Vrije Universiteit Brussel
Building E
Pleinlaan 2
1050 BRUSSEL
BELGIUM

Lab Technician

Veerle Quivreux — Wed, 09 Nov 2011 08:00:55 GMT

The Lamkanfi lab at the Department of Medical Protein Research of VIB and Ghent University is working on the role of NOD-like receptors and inflammasomes in the immune system. To support this front-line research, we are currently looking for a laboratory technician with experience in animal models and molecular biology. The successful candidate will work in a young, dynamic and internationally-oriented research team.
VIB and Ghent University are exciting, interdisciplinary research institutes with excellent facilities (e.g. proteomics, next-gen sequencing) and research groups in e.g. immunology, microbiology, genetics, molecular and cellular biology and translational research. The Lamkanfi lab is located at the Rommelaere campus in the city center of Ghent, a vibrant, international city in the heart of Europe.
We offer full-time employment with a one year contract that is extendable upon positive evaluation.

Technical support

Gent

February 2012

Please send your cover letter, CV and 1-2 references by e-mail to Prof. Mohamed Lamkanfi. Informal inquiries regarding this position can be sent to the same email address.

VIB Department of Medical Protein Research, UGent
Albert Baertsoenkaai 3
9000 GENT
BELGIUM

8 PhD Positions in Life Sciences for international students

VIB\jogan — Wed, 02 Nov 2011 12:49:52 GMT

Kick-start your scientific career and apply now for the VIB International PhD Program in Life Sciences. You will work in a centre of excellence, backed by first class research facilities and training in our multidisciplinary, international scientific community. At VIB, scientists work at the frontlines of molecular biology, cell biology, developmental biology, structural biology, plant systems biology, genetics, biochemistry and microbiology. VIB is a life sciences research centre in Flanders, Belgium, in the heart of Europe.

Selected candidates will be fully funded with a yearly net salary of €23.500 and are expected to start in October 2012. Deadline for application: 15 February 2012

Visit http://www.vib.be/phd for more info

Ph.D.

Antwerpen-Brussel-Gent-Leuven

October 2012

Visit http://www.vib.be/phd

Deadline for application: 15 February 2012

Ph.D. Student Physiological Studies

Veerle Quivreux — Mon, 05 Sep 2011 12:43:00 GMT

The Laboratory of Glia Biology is a new group based at the VIB Department of Molecular and Developmental Genetics in Leuven. We are currently looking for a highly motivated Ph.D. student to join our team at the beginning of 2012. We are offering a project on physiological studies of astrocyte function.

Background:
Astrocytes are the most abundant cell type in the mammalian brain, where they are known to play an essential role in development, maintenance and function of the nervous system. However, the precise molecular pathways driving these processes remain to be elucidated.

The Project:
To complement our biochemical analysis of astrocyte function, we are looking to establish high-resolution fluorescence microscopy techniques in the group - including multi-color Total Internal Reflection (TIRF) and Photoactivated Localization Microscopy (PALM). Using isolated astrocytes, you will then apply these techniques to investigate the spatial and function interactions of protein and lipid targets identified by our lab.

Ph.D.

Leuven

January 2012

Please send a covering letter and CV (including the contact details of three referees) to Dr. Matthew Holt

VIB Department of Molecular and Developmental Genetics, K.U.Leuven
Onderwijs en Navorsing
Campus Gasthuisberg
Herestraat 49, box 602
3000 LEUVEN
BELGIUM

Ph.D. Student Biochemical Dissection

Veerle Quivreux — Mon, 05 Sep 2011 12:39:22 GMT

The Laboratory of Glia Biology is a new group based at the VIB Department of Molecular and Developmental Genetics in Leuven. We are currently looking for a highly motivated Ph.D. student to join our team at the beginning of 2012. We are offering a project aiming at the biochemical dissection of signaling pathways in astrocytes.

Background:
Astrocytes are the most abundant cell type in the mammalian brain, where they are known to play an essential role in development, maintenance and function of the nervous system. However, the precise molecular pathways driving these processes remain to be elucidated.

The Project:
In this project, we plan to analyze the protein and lipid signaling pathways involved in astrocyte function – by applying powerful mass-spectrometry based methods. The function of identified proteins will then be investigated using in vitro recombinant protein methods and tissue culture techniques.

Ph.D.

Leuven

January 2012

Please send a covering letter and CV (including the contact details of three referees) to Dr. Matthew Holt

VIB Department of Molecular and Developmental Genetics, K.U.Leuven
Onderwijs en Navorsing
Campus Gasthuisberg
Herestraat 49, box 602
3000 LEUVEN
BELGIUM