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An introduction to Nitro dimethyl terphthalate

noreply@blogger.com (Abhishek Chemicals) — Sun, 8 Sep 2013 22:47:00 -0700

We are a leading manufacturer of Nitro dimethyl terphthalate, a chemical that is widely known as Drug Intermediates and Pharmaceutical Intermediates. It finds its application in manifold pharmaceutical utilities and is manufactured in conformity with the global norms and quality standards. All our products are accessible at market leading prices and are available to clients in an efficient and reliable manner. Further, all our products are thoroughly checked using different quality control systems based on several parameters and are highly admired for its proper packaging, authentic features and for being highly efficient.

This acid is manufactured by ammonolysis of dialkyl nitroterephthalates. Terephthalamic acid is useful as an intermediate in the manufacturing of difunctional compounds and also in the manufacturing of polybenzimidazoles and aromatic polyamides. Nitro dimethyl terphthalate is used in Cetalopam Drug, pigment intermediates and also in the preparation of Anti Depression Drugs. This product appears off white, yellow crystalline in nature. The chemical compositions are proportionally arranged to acquire the desired product.

The other synonyms with which this acid is also known as includes;

NDMT
Nitro, Dimethyl ester
Terephthalic acid
4-dicarboxylate, 5292-45-5
Dimethyl 2-nitrobenzene-1
Dimethyl 2-nitroterephthalate
Nitroterephthalatedimethylester
Dimethyl nitroterephthalate

Chemical Properties

Molecular Formula: C10H9NO6
CAS No. 5292-45-5
Molecular weight: 239.18156
Melting point: 73 to 76 degree Celsius (lit)
Purity by HPLC: 98.5 Min
Density: 1.272
DMT: 0.5% max
Water solubility: Nitro dimethyl terphthalate is insoluble in water

The chemical 5-Nitro salicylic acid compounds are highly purified which are utilized to attain high quality products. They form to be of great commercial value and are appreciated for their optimum quality which is as per the International standards. With the advancement of technology new and innovative ways of preparation of the chemical has improved the quality substantially. The molecular properties of such chemical substances are used in various manufacturing applications which are recognized in the global platform. Health and safety measures need to be taken during the preparation of the chemical. Stringent administration is implemented during the preparation of the product. Laboratory checks are conducted before being released in the market which assures of a flawless product.

Understanding 4-Nitrophthalimide

noreply@blogger.com (Abhishek Chemicals) — Sun, 25 Aug 2013 22:11:00 -0700

The chemical industry has become an integral part of the economy. The industry has a wide spectrum of category which includes both forms of chemical compounds that includes organic and inorganic chemicals which are used in a variety of applications. The production of chemical compounds or substances goes hand in hand with the storage as both the task is very tedious, which needs special attention. The product 4-Nitrophthalimide is a pale yellow colored powdered substance which is being used in pharmaceutical and dyestuff industries. The product has been accepted globally and further research and developments is about to make the product more usable to meet the customer demands.

There are other synonyms which are associated with these derivatives and are known as:

4-Nitro-1
Imide 5-Nitrophthalimide
2-Benzene Dicarboxylic acid
3-DIONE 5-NITROPHTHALIMIDE 5-NITRO-1H-ISOINDOLE-1
3-Dione 5-NITROISOINDOLINE-1
3-DIHYDRO-2H-ISOINDOL-1
3 (2H) -DIONE 5-NITRO-1
3-Dione, 5-Nitroisoindole, 5- Nitroisoindoline

The powdered substances are sparingly soluble in water, alkali and acetone. Hydrolysis is a possibility. This belongs to the reactive group of amines, pyridines, phosphines, Nitro, nitrate and nitrate compounds, nitroso and organics.

Chemical properties of 4-Nitrophthalimide:

Empirical formula: C8H4N2O4
Molecular weight: 192.13
Purity : 99% min
Melting point: 201 to 202 degree Celsius
Water solubility : Less than 0.01 g/100 ml at 18 degree Celsius
Density : 1.609g/cubic cm

This chemical compound is a nitrate amine and the amines are generally combustible. The amines are chemical bases to neutralize the 5-Nitro salicylic acid which help in the formation of salt water. This formation of acid base is exothermic. This chemical is stable, combustible and incompatible with water, moisture, strong bases and strong oxidizing agents. The storage requires to be maintained in a tight and closed container. The room should be cool, dried, well ventilated and should be kept away from substances which are incompatible. The incompatible absorbents are:

Mineral based and clay based absorbents
Cellulose based absorbents
Expanded polymeric absorbents

4-Nitrophthalimide is used in pharmaceutical industries and features in a basic Intermediate of Cetalopam Drug and is utilized in the making of anti depression drugs. The powdered substances and intermediates are being checked under properly defined parameters which ensure flawless range to the customers.

Facts about N-Carbethoxy-4-piperidone

noreply@blogger.com (Abhishek Chemicals) — Sun, 18 Aug 2013 22:15:00 -0700

N-Carbethoxy-4-piperidone is one of the derivatives of N-Methyl Piperidone derivatives . New and affordable intermediates are being developed by manufacturers who are keen to deliver outstanding support and value to the customers. Other such chemicals under this derivative are N-Methyl-4-Hydroxy piperidine, N-Carbethoxy-4-Amino piperidine, N-Carbethoxy-4-Hydroxy piperidine, N-Carbethoxy-4-piperidone, N-Methyl-4-Amino piperidine, N-Methyl-4-Chloro piperidine and N-Methyl-4-Hydroxy piperidine. The manufacturing and preparation of this derivative are the results of an intensive research which can be utilized as bulk intermediates in various industries and laboratory researches. The demand for such derivatives has created zeal amongst the chemical researchers.

The Piperidone derivative N-Carbethoxy-4-piperidone appear to be clear colourless which can vary up to pale yellow colored liquid. This is basically the chemical name by which the general manufacturers and the customers refer to. Chemicals are produced in the same way all over the globe with the support of the same preparation process and chemical reactions. The only thing which differs is the availability of the raw materials in abundance so as to satisfy the demands of the customers. Penfluridol is utilized as a raw material in the manufacturing of the product. The other preparatory product which is of great value is 4-(2-Keto-1-Benzimidazolinyl piperidine).

The other names by which N-Carbethoxy-4-piperidone are known as N-ETHOXYCARBONYL-4-PIPERIDONE, N-Carbethoxy-4-Piperidone99%, N-CARBOETHOXY-4-PIPERIDONE, N-Carbithoxy-4-Piperidone, 1-CARBETHOXY-4-PIPERIDONE, N-CARBETHOXY-4-PIPERIDONE, carbethoxy-4-piperidone, N-Carbethoxypiperidone, AURORA KA-3057. This chemical product is represented by the molecular formula C8H13NO3. The IUPAC name by which it is identified is ethyl 4-oxopiperidine-1-carboxylate

The salient features are:

Formula weight: 171.19
Boiling point: 95 to 98 degree Celsius ( 1 mmHg)
Refractive Index: n20/D 1.475 (lit.)
Flashing point: 190 degree Fahrenheit
MOL File: 29976-53-2 mol
H-Bond donor: 0
H-Bond acceptor: 3
Exact mass: 171.08
Mono Isotropic mass: 171.08
Complexity: 181
Formal charge: 0
Topological polar surface area: 56.6

Uses:

This is utilized in the preparatory procedure of N-Methyl-4-piperidone which are identified as antihypertensive agents, and ?-carboline derivatives as potential serotonergic agents. This chemical product can also be utilized as an impurity of Loratadine.

This derivative is slightly soluble in water and has been tested as an irritant which is one of the hazardous notes for all the customers to be aware as a precautionary which needs to be kept in consideration while using the chemical. The chemical can be synthesized in a customized way depending on the requirement and specifications of the clients. This N-Carbethoxy-4-piperidone are fine intermediate chemicals whose range product categories are pharmaceutical intermediates, piperidones, piperazines, pipeiridines, boronic acid and heterocyclic compounds.

An overview of 5-Nitro salicylic acid

noreply@blogger.com (Abhishek Chemicals) — Wed, 31 Jul 2013 21:59:00 -0700

5-Nitro salicyclic acid is a chemical which is a known form of Salicylic Acids. Being accurate in composition, such chemicals are known for their specific pH value, consistency and higher shelf life. With the involvement of technical advancements such chemicals are being processed to serve diverse industries which comply with International standards in terms of quality and compositions. This form of salicyclic acid is yellow powdered or crystalline which is stable and incompatible with acids, acid chlorides, acid anhydrides, chloroformates as well as strong oxidizing agents.

The synonyms which are used to identify this compound are:

Anilotic Acid
Benzoic acid, 2-hydroxy-5-Nitro
5-Nitro-2-oxide-benzoate
2-Hydroxy-5-nitrobenzoic acid
5-Nitro-2-hydroxybenzoic acid
Salicylic acid, 5-Nitro- (8CI)
Salicylic acid, 5-Nitro

Chemical properties of 5-Nitro salicyclic acid:

Molecular Formula: C7H5NO5
Molecular Weight: 183.12
Freezing and Melting Point:228 - 231 deg C
Solubility: 1g/1475ml in water
Odor: odorless
Density: 1.65 g/cubic cm

Such chemicals are stable under normal pressure and temperature which needs to be maintained. Storage facilities and utilization of this product are well equipped to avoid incompatible materials and dust generation. Such type of compounds is incompatible with strong oxidizing agents and bases. Nitrogen Oxides, carbon dioxide and carbon monoxide are hazardous decomposition products related to this compound. Precautions should be maintained while handling the chemical product which requires it to be avoided from direct contact with skin, eyes and clothing. During the handling of this chemical a proper ventilation maintenance is a basic requirement

The 5-nitrosalicylic acid is produced by using the combinational process of nitration and hydrolysis of o-chlorobenzoic acid. The nitration process yields the intermediate 2-Chloro-5-nitrobenzoic acid. The generation of nitration is 95.7% and that of hydrolysis is 98.3%. The final product which generates is 99.8% after proper recrystallization by ethanol solution. The solubility of this chemical is dependent on the concentration of nitric acid.

5-nitrosalicylic acid is an organic phenolic compound which is extensively utilized in forming slyvite, sodium salts and organic drug synthesis which act as intermediates. The chemical is checked and analyzed as per the International standard specifications which meet the customer requirements.

The Basics Of N-Methyl-4-piperidone

noreply@blogger.com (Abhishek Chemicals) — Tue, 25 Jun 2013 22:21:00 -0700

Chemical compounds are largely utilized in various industrial processes. The compounds are formulated with various types of chemicals. The chemical advancements have a vast effect on the processing of chemical substances which are used in the preparatory methods of different types of products. N-Methyl-4-piperidone is one such type of N Methyl Piperidone derivative which bears unique characteristics. The molecular properties possessed by this chemical make it an effective variety for use in manufacturing industries. This chemical bears a complex structure which is associated with a varied list of properties. This type of chemicals is required to be stored at room temperature which needs be taken care of. The storage should be made in such a way that the chemical does not come in contact with light and air. Basically the storage system for such chemicals should be a dry warehouse. The basic facilities for utilizing and storage of the chemical should be well equipped with an eyewash facility. Safety measure area must to be kept in mind while dealing with the chemicals

The chemical appearance of N-Methyl-4-piperidone varies from clear, colourless to yellow liquid. The molecular formula by which it is represented in chemical terms is C6H11NO.

•    Molar Mass: 113.16 g/mol
•    Boiling point: 55-58 degree Celsius, at 10 mm HG
•    Density: 0.920 g/ml
•    Flash point: 60 degree Celsius
•    Moisture content: 0.5% maximum
•    Purity: 98.0% minimum
•    Refractive index: 1.46 to 1.462

The application of the N Methyl piperidone derivative can be seen in pharmaceutical intermediates, dyestuff intermediates and manufacturing processes. Pharmaceutical products are stringently required to be absolutely pure in chemical properties and proportion which assures optimum quality. The supply of such qualitative product has been recognized and appreciated by the various industries which have increased the demand in a positive manner. The satisfaction of the clients is what is aimed for and are kept inn consideration while preparing such chemicals.

The product N-Carbethoxy-4-piperidone is well utilized by both medium and large scale industries are appreciated in the domestic as well as in the international market. The chemical has been accepted for its accuracy, composition, purity, stability and reasonable price.

Basics about N-Methyl-4-piperidone

noreply@blogger.com (Abhishek Chemicals) — Mon, 17 Jun 2013 22:00:00 -0700

N-Methyl-4-piperidone is a chemical compound which is a complex structure and has unique chemical and physical properties. The use of such molecular properties is exploited in various manufacturing industries. Modern technologies and equipments have enabled the manufacturers to cope up with the demands of the market and satisfy the requirements of the users. Investigations and corrective measures are followed in each and every process during the manufacturing of the product which helps to satisfy the customer requirement. The product is known for its accuracy, purity and reasonable price. The appearance of the product varies from clear, colourless to yellow.

Salient properties of N-Methyl-4-piperidone

Molecular Formula: C6H11NO
Product Name: N-Methyl-4-Nitro Phthalimide
Alias: 1-Methyl-4-piperidone
Formula weight: 113.16
Refractive index: 1.46-1.462
Boiling point:55-58 ºC (10 mmHg)
Density: 0.98
Flash point: 58 ºC
Purity : 98.0% minimum
Moisture : 0.5% max
Complexity: 90.7
Heavy atom count: 20.3
Content: 98%
H-Bond Donor: 0
H-Bond Acceptor: 2
Chemical stability: Under normal pressure and temperature

The chemical has excellent applications and are used as solvents and are utilized as intermediates for the synthesis of organic substances. The compounds ensure their consistency in quality which makes it a significant product which is very much important in the making of medicines and other pharmaceutical related product. N-Methyl-4-piperidone has been able to satisfy the demands of the dyestuff intermediate and pharmaceutical intermediate.

The chemical is tested to be easily dissolvable in water, acetone and other solvents which are organic in nature. The chemical compounds are formulated by the industrial manufacturers with the support of high quality materials which are checked under the stringent supervision of skilled resources are technically sound in this aspect. The product is an accepted form where accurate compositions in combination with solubility and purity are vital results. Packaging of such N-Carbethoxy-4-piperidone compounds becomes very much important. The chemical is required to be stored away from air and light. This is where the dry warehouses come into the effect. The room temperature is also maintained as per the specifications. The chemical product is appreciated and recognized and are in accordance with the International standards.

Facts about 5-Amino salicylic acid

noreply@blogger.com (Abhishek Chemicals) — Tue, 11 Jun 2013 23:08:00 -0700

We manufacture quality 5-Amino salicylic acid that is utilized in a wide assortment of drugs. Made with premium raw material, this intermediate manufactured by our team of experts has been appreciated and approved both in India and across the world. We have a fully-equipped testing laboratory with up to date machineries that enables us in providing qualitative chemicals with accurate composition. Our proficient experts have helped us to carve a niche for ourselves in the domain of chemicals and intermediates. We stand tall as reputed manufacturers of superior quality chemicals. Manufactured using best grade chemicals under the stringent surveillance of quality auditors and chemists, our entire range of 5-Amino salicylic acid stands high with respect to purity and hence is highly demanded across India.
5-ASA or 5-Amino salicylic acid is a metabolite; a potential pharmacologically active elements of sulphasalazine, which is highly effective in treating ulcerative colitis and Crohn's disease.
Synonyms: 5-Amino salicylic acid (Mesalazine), Mesalazine5-Aminosalicylic acid, 5-Aminosalicyclic acid, Sodium 5-aminosalicylate, 5-amino-2-hydroxy, Benzoic acid, Mesalamine, 5-amino-2-hydroxy-benzoic acid, 5-Amino Salicylic Acid, 5-amino-2-hydroxy-benzoic acid hydrochlorid and Aminosalicylsaeur.

Specifications

Molecular Formula: C7H7NO3
Form: powdery crystals
Colour: off-white to gray
Storage temperature: 2 to 8 degree Celsius
Melting point: 275 to 280 degree Celsius (dec.) (lit.)
Water and Air Reactions: water insoluble and sensitive to moisture.
Fire Hazard: 5-Amino salicylic acid is likely to be combustible.
Reactivity profile: it is mostly incompatible with acids, chloroformates, strong oxidizers, acid anhydrides and acid chlorides
Molecular weight: 153.14
EINECS: 201-919-1
Boiling point: 403.9 degree Celsius at 760 mmHg
Solubility: <0.1g per 100 ml at 21 degree Celsius in water
Density: 1.491 g per cm3
Flash point: 198.1 degree Celsius

Caution

Use within an adequate ventilation
Reduce dust generation as well as accumulation
Avoid contact with skin and eyes and also clothing
Avoid inhalation
Avoid ingestion
Keep it in an airtight container
Wash hands thoroughly after handling

Storage

Store 5-Amino salicylic acid in an airtight container and keep in a well-ventilated, cool and dry place.
Keep it away from any incompatible substance.

An outline of 5-Amino salicylic acid

noreply@blogger.com (Abhishek Chemicals) — Fri, 7 Jun 2013 21:40:00 -0700

A variety of chemical compounds and solvents have become a general requirement for most manufacturing industries to make assorted products. These are utilized in amalgamation with other chemical substances. The properties of the chemicals play a major role in identifying the role of individual substances. This involves a lot of laboratory investigations by the research and development teams. 5-Amino salicylic acid is one such type of chemical which is exploited on a large scale for use in the pharmaceutical industry. The use of such a chemical has made it popular which has seen a rise in demand for such products. This is one of the derivatives of salicylic acid which acts as antioxidants and traps the free radicals which in a way are damaging byproducts of metabolism. The colour of such a product varies from off white to gray which is odourless. Purity of such product is estimated at more than 99%

Properties:

Molecular Weight 153.14
Melting point: 275-280 °C (dec.)(lit.)
Storage temp: 2 to 8 degree Celsius
Flash point: 279 to 281 degree Celsius

5-Amino salicylic acid is a metabolite product which is a crystalline solid in nature. Formally it is also termed as 5-amino-2-hydroxy-benzoic acid whose chemical formula is C7H7NO3. 5-AS and Mesalamine are also used as synonyms to represent the chemical compound.

These are probable pharmacologically active chemical component of sulphasalazine which is a remedial drug utilized in the healing of ulcerative colitis and Crohn's disease. This is combustible and is incompatible with acids, acid anhydrides, acid chlorides, strong oxidizers and chloroformates. 5-Amino salicylic acid belongs to the reactive groups which are phenols, cresols, acids, carboxylic, amines and aromatic. Toxic fumes of carbon dioxide, nitrogen oxides and carbon monoxides are emitted when ignited to decomposition. 5-Aminosalicylic acid inhibits prostaglandin 15-hydroxydehydrogenase (PGDH) in the placenta and lungs of the human body. This also has the ability to disrupt tumor necrosis factor alpha. These are categorized as anti- inflammatory compounds which have the capability to inhibit leukotriene formation in leukocytes in the human body.

Packaging of such chemical products is arranged as per the client's requirement which depends on the nature of the application and storage mechanism.

A brief outline of Nitro dimethyl terphthalate

noreply@blogger.com (Abhishek Chemicals) — Mon, 27 May 2013 22:03:00 -0700

Nitro dimethyl terphthalate is the result of an extensive investigation and chemical testings which have been done by researchers and are of utmost importance to manufacturing industrial domain. The manufacturing companies endeavor towards sustaining superior quality standards which comply with the International norms and standards. Substantial research of this existing chemical product is also in continuity to facilitate the clients with more desired specifications which will assist them in the manufacturing of other products utilizing this. With new ways of chemical processes and chain reactions assorted types of products can be produced. This chemical product is extensively exploited in the pharmaceutical industries where the chemical is used as pharmaceutical intermediates as well as drug intermediates.

With different types of research in different countries the chemical name of Nitro dimethyl terphthalate are also used as Dimethyl nitroterephthalate, Nitroterephthalatedimethylester, Dimethyl 2-nitroterephthalate, Dimethyl 2-nitrobenzene-1, 4-dicarboxylate, 5292-45-5, Terephthalic acid, NDMT and Nitro Dimethyl ester. With the necessary proportion of the various chemicals the product prepared and manufactured are off white and yellow crystalline in nature. The purity of the product is maintained on a higher level or have been appreciated on the commercial front of the global market for their fine quality.

The Salient properties:

Molecular Formula: C10H9NO6
Molecular weight: 239.18
Melting point: 73 to 76 degree Celsius (lit)
Density: 1.272
Purity by HPLC: 98.5 Min
DMT: 0.5% max

Nitro dimethyl terphthalate is an insoluble product. The manufacturing process involves the ammonolysis of dialkyl nitroterephthalates which is required during the process. The Ammonolysis in combination with hydrolysis is used in the preparation of the product which is processed in a stirred vessel under pressure. Purification and filtration are carried out after the extraction of the mixed compounds to attain the desired product. Stringent administration and observations are done by the manufacturers to avoid any flaw in the quality. Once the product is manufactured it is made to pass through the laboratories and the quality control departments to ensure highest quality of the chemical. The chemical industry has been on the precautionary side when it comes to packaging and storage. Proper packaging is a must to maintain Nitro dimethyl terphthalate at conditions specified by the Laboratory departments.

5-Nitro salicylic acid: a brief outline

noreply@blogger.com (Abhishek Chemicals) — Thu, 23 May 2013 22:16:00 -0700

5-Nitro salicylic acid finds its application in various industries and is processed with the help of latest techniques. Along with being appreciated for its accurate composition, this chemical has also gained applause for its higher shelf life. Not only is it safe but it also complies as per the international quality norms and standards. Formulated under hygienic surroundings and by our expert professionals, this acid is generally utilized to prevent and clear pimples and acne. Clients can avail this in hygienic packaging options according to their needs. Our skilled manufacturers strictly examine this offered acid on certain parameters for ensuring its effectiveness prior to the final dispatch.

Specifications

Name: 5-Nitrosalicylic acid
Molecular formula: C7H5NO5
Synonyms: Anilotic acid, 2-Hydroxy-5-nitrobenzoic acid, 5-Nitro-2-oxidobenzoate
Colour: Yellow crystalline
Molecular Weight: 183.12
EINECS: 202-548-8
CAS Registry Number: 96-97-9
Melting/freezing point: 228-231 degree Celsius
Solubility: 1g of 5-Nitrosalicylic acid/1475ml in water

Uses: forms slyvite, sodium salt and is used for organic synthesis intermediates
Extinguishing media: make use of water spray, dry chemical, chemical foam or carbon dioxide

Spills/leaks: sweep up or vacuum material and place it into an appropriate disposable container. Provide ventilation and prevent generating dusty conditions. Avoid the chemical to enter the environment.

Engineering controls: facilities utilizing or storing this material must be equipped with a safety shower and an eyewash facility. Use adequate ventilation for keeping airborne concentrations low.

Stability: it is stable under normal pressures and temperatures
Incompatibility with other any other material: strong bases and strong oxidizing agents
Conditions to avoid: dust generation, incompatible materials
Hazardous polymerization: this will not occur
Hazardous decomposition products: these include nitrogen oxide, carbon dioxide or carbon monoxide.

Caution

Avoid contact of 5-Nitro salicylic acid with skin, eyes and clothing
Avoid inhalation and indigestion
Use this acid with adequate ventilation
Reduce dust generation as well as accumulation
Do not empty it into drains

Storage

Store it in an airtight container
Store it in a cool and dry place