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    <title>AlphaRx</title>
    <description>AlphaRx</description>
    <link>http://agoracom.com/ir/alpharx</link>
    <language>en-US</language>
    <pubDate>14 Sep 2009 12:05:00 GMT</pubDate>
    <lastBuildDate>20 Jan 2010 15:04:26 GMT</lastBuildDate>
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      <title>[Press Release] AlphaRx Presents Company Overview and New Product Candidates at the Rodman...</title>
      <guid>message_1215517</guid>
      <pubDate>14 Sep 2009 12:05:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/1215517</link>
      <description>
        <![CDATA[<p style="text-align: justify;"><strong style=""><span style="">AlphaRx Presents Company Overview and New Product Candidates at the Rodman Renshaw Healthcare Conference</span></strong><br /><br />MARKHAM, ON, Sept 14, 2009 - <strong>AlphaRx Inc. (OTC BB: ALRX)</strong>. Speaking at the 11th Annual Rodman Renshaw Healthcare Conference in New York City, AlphaRx Director Dr. David Milroy presented a company overview focusing on the Company's product pipeline, nano drug delivery platform and the significant developments anticipated within the next 12 months. In Summary, AlphaRx will have 3-4 products in different stages of clinical development by the end of 2010, which have major market indications and opportunities, producing a portfolio of short to long term drug candidates to position the company for stable and sustainable growth. In addition, AlphaRx presented 2 new product candidates ARX1088 and ARX2038 which are being developed for herpes and lipid management respectively. These products have excellent safety profile and have over 25 years of successful clinical applications outside the US. AlphaRx is developing a new dosage form for ARX1088 and ARX2038 and planning to initiate Phase II clinical trails in the later part of 2010.<br /><strong><span style="font-weight: normal;"><br /></span>About ARX1088</strong></p>
<p style="text-align: justify;">The active ingredient in ARX1088 is an orally active interferon inducer. It primarily acts as an inducer of type I, alpha or beta interferon. In humans, these interferon levels double as early as four hours after administration of the drug. After 12-24 hours the levels can be one hundred or even several thousand fold higher, with maximum level achieved at 48 hours. It is a drug that is currently approved to treat certain anti-viral indications outside USA. ARX1088 is being developed as a topical treatment for herpes Simplex 1 and 2, as the mechanism of action is not directed at killing the virus, but through boosting the host's own immune system.<br /><strong><span style="font-weight: normal;"><br /></span>About ARX2038</strong></p>
<p style="text-align: justify;">The active ingredient in ARX2038 is a synthetic compound with a combination of unique properties. It demonstrates, heart, neuroprotective and cholesterol lowering properties.</p>
<p style="text-align: justify;">It has extremely low toxicity (no signs of toxicity at 10,000 mg/kg) and produces no teratogenic, mutagenic or carcinogenic effects. Allergic reactions are extremely rare.</p>
<p style="text-align: justify;">This compound significantly decreases cholesterol levels by up to 36%, LDL by 20%, triglycerides by 13% and elevates HDL by 47%. ARX2038 is a unique extended release formulation of this compound.</p>
<p style="text-align: justify;"><strong>About AlphaRx Inc.</strong></p>
<p style="text-align: justify;">AlphaRx is a specialty pharmaceutical company dedicated to developing proven therapies by reformulating FDA approved and marketed drugs which through the application of its proprietary site-specific nano drug delivery technology, offers improved medical benefits and a potential for significant commercial product development.<br /><strong><span style="font-weight: normal;"><br /></span>Forward Looking Statements:</strong></p>
<p style="text-align: justify;"><strong> </strong></p>
<p style="text-align: justify;"><em>This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the Company.</em></p>]]>
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      <title>[Press Release] ALPHARx to Present at Rodman Renshaw Annual Global Investment Conference</title>
      <guid>message_1209451</guid>
      <pubDate>03 Sep 2009 12:40:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/1209451</link>
      <description>
        <![CDATA[<p>
<p style="text-align: justify;">MARKHAM, ON, Sept 03, 2009 - <strong style="">AlphaRx Inc. (OTC BB: ALRX)</strong>, an emerging biopharmaceutical company utilizing proprietary drug delivery technology to develop novel formulations of drugs, today announced that it is scheduled to make an investor presentation at the Rodman Renshaw Annual Global Investment Conference at 2:25 pm EDT on Friday, September 11, 2009. The conference will be held at the New York Palace Hotel, September 9-11, 2009.</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;">AlphaRx will make its presentation in the Spellman Salon (5th Floor) and a live webcast of the presentation will be available via a link provided at</p>
<p style="text-align: justify;"><a href="http://www.wsw.com/webcast/rrshq15/alrx" target="_blank"><a href="http://www.wsw.com/webcast/rrshq15/alrx" target="_blank">http://www.wsw.com/webcast/rrshq15/alrx</a></a> . An archived replay of the presentation will be available for a period of 90 days from the date of the presentation</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;"><strong style="">About AlphaRx Inc.</strong></p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;">AlphaRx is a specialty pharmaceutical company dedicated to developing proven therapies by reformulating FDA approved and marketed drugs which through the application of its proprietary site-specific nano drug delivery technology, offers improved medical benefits and a potential for significant commercial product development. For more information, please visit <a href="http://www.alpharx.com/" target="_blank">www.AlphaRx.com</a>.</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;">This news release may contain forward-looking statements made pursuant to the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. While these statements are meant to convey to the public the company's progress, business opportunities and growth prospects, readers are cautioned that such forward-looking statements represent management's opinion. While management believes such representation to be true and accurate based on the information available to the company, actual results may differ materially from those described. The company's operations and business prospects are always subject to risks and uncertainties. Important facts that may cause actual results to differ are set forth in the company's periodic filings with the U.S. Securities and Exchange Commission.</p>
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      <title>[Press Release] AlphaRx Concludes GAI-122 Formulation Development Intended For...</title>
      <guid>message_1205774</guid>
      <pubDate>27 Aug 2009 12:04:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/1205774</link>
      <description>
        <![CDATA[
<p style="text-align: justify;">
<p style="text-align: justify;"><strong style=""><span style="font-size: 14.0pt;">AlphaRx Concludes GAI-122 Formulation Development Intended For The Prevention of Delirium</span></strong></p>
<br />MARKHAM, ON, Aug 27, 2009 - <strong>AlphaRx Inc. (OTCBB: ALRX)</strong> and Gaia BioPharma Limited announce an update on their programme to develop a preventive treatment for delirium caused by prolonged surgery. Each year in the United States, as many as 7 million hospitalized adults experience delirium, a state of confusion caused by a sudden alteration of mental status. Currently, there are no approved drugs available in the United States to prevent or manage delirium.<br /></p>
<p style="text-align: justify;">"Developing post-operative delirium prolongs the length of a patient's hospital stay, increases the risk of post-hospitalization transfer to a nursing home and doubles the risk of death. As the national burden of delirium to the health care system may be as high as $152 billion annually, there is an urgent need to identify a safe and effective drug therapy to reduce the incidence of delirium and its' associated health care costs," said Dr. Peter Carlen, a clinical neurologist collaborating with AlphaRx in the GAI-122 delirium program.<br /></p>
<p style="text-align: justify;">GAI-122 is proceeding to the clinical trial materials manufacturing stage and is expected to enter clinical trials by mid-2010. GAI-122 is protected by 4 US patent applications.</p>
<p style="text-align: justify;">In October 2008, AlphaRx licensed GAI-122 to Gaia BioPharma. Under the terms of the amended agreement, AlphaRx is eligible to receive milestone payments of up to $50 million for the successful development and commercialization of GAI-122, as well as royalties on worldwide sales. In addition, Gaia BioPharma assumes all development costs.<br /></p>
<p style="text-align: justify;"><strong>About GAI-122<br /> <br /> </strong></p>
<p style="text-align: justify;">GAI-122, an investigational, injectable nanoemulsion formulated with AlphaRx's proprietary drug delivery technology, has been shown to provide significant neuro-protection in multiple in vitro and in vivo animal studies suggesting that this injectable nanoemulsion formulation has the potential to prevent postoperative delirium. In rat model studies, injected GAI-122 ameliorates learning and memory disturbances produced by cerebral embolization, cerebral ischemia or lesions in the basal forebrain, the area of origin of the acetylcholine neuron system projecting into the cerebral cortex, hippocampus and amygdala. In clinical tests, an oral form of GAI-122 has been shown to be effective in preventing psychological deficits, such as a decline in memory retention and orientation.<br /></p>
<p style="text-align: justify;"><strong>About AlphaRx Inc.<br /> <br /> </strong></p>
<p style="text-align: justify;">AlphaRx is a specialty pharmaceutical company dedicated to developing proven therapies by reformulating FDA approved and marketed drugs which through the application of its proprietary site-specific nano drug delivery technology, offers improved medical benefits and a potential for significant commercial product development.<br /></p>
<p style="text-align: justify;"><strong>About Gaia BioPharma<br /> <br /> </strong></p>
<p style="text-align: justify;">Gaia BioPharma Limited, a privately held, early stage biopharmaceutical company focused on hospital-based injectable therapeutics. Gaia BioPharma seeks to address key unmet therapeutic needs by taking established compounds and changing their administration routes to create patent-protected, value-added products.<br /></p>
<p style="text-align: justify;"><strong><em>FORWARD LOOKING STATEMENTS:<br /> <br /> </em></strong></p>
<p style="text-align: justify;"><em>This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the Company.</em></p>
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      <title>[Press Release] AlphaRx Completes Lyophilization Process for Zysolin(TM)</title>
      <guid>message_1201887</guid>
      <pubDate>17 Aug 2009 12:02:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/1201887</link>
      <description>
        <![CDATA[<p>
<p style="text-align: justify;">MARKHAM, ON, Aug. 17 - <strong style="">AlphaRx Inc. (OTC BB:ALRX.OB</strong>), an emerging biopharmaceutical company utilizing proprietary drug delivery technology to develop novel formulations of drugs, is pleased to announce that it has completed the lyophilization process for Zysolin(TM), allowing the company to proceed to clinical batch material manufacturing for human trials. This process has been solely developed by AlphaRx's scientists and the resulting formulations have been successfully tested in animal studies conducted by the U.S. Army under a Material Transfer Agreement.</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;">'This is a technological milestone for AlphaRx and the entire nanomedicine industry,' commented Dr. Joseph Schwarz, AlphaRx's Chief Scientist. 'It is well known that many FDA approved ingredients used in nanomedicine formulations can not be readily lyophilized, representing the major obstacle to their therapeutic development, a critical step which we have overcome.'</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;">Many biotechnology products require lyophilization, a process of freeze-drying sterile solutions to permit a shelf stable dosage form. By removing the water from the material and sealing the material in a vial, it can be easily stored, shipped, and later reconstituted to its original form for administration.</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;">Zysolin(TM) is protected by 3 U.S. patents pending and the Company plans to file a new patent application to protect this new process.</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;"><strong style="">About Zysolin(TM)</strong></p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;">Zysolin(TM) is a Tobramycin compound, encapsulated in AlphaRx's Nano Drug Delivery Platform, intended for the adjunctive treatment of Gram-negative pneumonia in intubated and mechanically-ventilated patients. Zysolin(TM) improves the intracellular activity of Tobramycin - in layman's term, increasing the drug concentration of Tobramycin inside human macrophages, thus improving its antibacterial activity against intracellular Klebsiella, Pseudomondas aeruginosa and Staphylococcus bacterial strains in pneumonia patients. The active ingredient in Zysolin(TM), Tobramycin, has a long-standing and proven clinical treatment record. Delivered by inhalation, using proprietary nanotechnology developed by AlphaRx, the company believes Zysolin(TM) will have an attractive safety, tolerability and efficacy profile when compared to injectible Tobramycin.</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;"><strong style="">About AlphaRx Inc.</strong></p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;">AlphaRx is a specialty pharmaceutical company dedicated to developing proven therapies by reformulating FDA approved and marketed drugs which through the application of its proprietary site-specific nano drug delivery technology, offers improved medical benefits and a potential for significant commercial product development.</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;"><strong style=""><em style="">Forward Looking Statements:</em></strong></p>
<p style="text-align: justify;"><em style=""> </em></p>
<p style="text-align: justify;"><em style="">This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the Company.</em></p>
<p style="text-align: justify;"><em style=""> </em></p>
<p style="text-align: justify;"><em style="">This press release is available on the company's official on-line investor relations site for investor commentary, feedback and questions.</em></p>
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      <title>[Press Release] AlphaRx Receives China Patent on Its Drug Delivery Platform</title>
      <guid>message_1201885</guid>
      <pubDate>10 Aug 2009 12:02:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/1201885</link>
      <description>
        <![CDATA[<p>
<p style="text-align: justify;">MARKHAM, ON, Aug. 10- AlphaRx Inc. (OTC BB:ALRX.OB), an emerging biopharmaceutical company utilizing proprietary drug delivery technology to develop novel formulations of drugs, is pleased to announce that it has been granted a comprehensive patent in China for its topical platform technology entitled 'Vehicle For Topical Delivery of Anti-Inflammatory Compounds.' The platform is an integral part of the Company's clinical stage product candidate Indaflex(TM).</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;">'China represents a major opportunity for AlphaRx because of its huge and growing market for innovative therapeutics products,' said AlphaRx President and CEO Michael Lee. 'The granting of this patent from the Chinese government intellectual property authority helps protect our innovative drug delivery technology and further endorses our competitive position in China.'</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;">In April 2006, AlphaRx licensed the global rights (with the exception of Asia and Mexico) for Indaflex(TM) to Proprius Pharmaceuticals, Inc. Under the terms of the agreement, AlphaRx is eligible to receive milestone payments of up to $116 million for the successful development and commercialization of Indaflex(TM), as well as double-digit royalties on sales. Proprius was acquired by Cypress Biosceince Inc., in March 2008.</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;"><strong style="">About Indaflex(TM)</strong></p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;">Indaflex(TM) is AlphaRx's topical NSAID (Non-Steroidal Anti-inflammatory Drug) formulation under clinical development for the symptomatic treatment of osteoarthritis. Arthritis is the most common chronic disease in North America and afflicts an estimated 10% of the world's population. Indaflex's active ingredient, Indomethacin, has a long-standing and proven clinical treatment record. With AlphaRx's enhanced proprietary delivery system, the company believes its' clinical effectiveness will be significantly enhanced compared to other topical preparations. Topical Indaflex(TM) delivery, the company hopes, may circumvent the significant GI side-effects commonly found with orally ingested NSAID's.</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;"><strong style="">About AlphaRx Inc.</strong></p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;">AlphaRx is a specialty pharmaceutical company dedicated to developing proven therapies by reformulating FDA approved and marketed drugs which through the application of its proprietary site-specific nano drug delivery technology, offers improved medical benefits and a potential for significant commercial product development.</p>
<p style="text-align: justify;"><strong style=""><em style=""> </em></strong></p>
<p style="text-align: justify;"><strong style=""><em style="">Forward Looking Statements:</em></strong></p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;"><em style="">This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the Company.</em></p>
<p style="text-align: justify;"><em style=""> </em></p>
<p style="text-align: justify;"><em style="">This press release is available on the company's official on-line investor relations site for investor commentary, feedback and questions.</em></p>
</p>]]>
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      <title>[Press Release] AlphaRx and Venturepharm Announce Collaboration Agreement</title>
      <guid>message_1201878</guid>
      <pubDate>04 Aug 2009 12:02:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/1201878</link>
      <description>
        <![CDATA[
<p>
<p style="text-align: justify;">MARKHAM, ON, Aug. - <strong style="">AlphaRx Inc. (OTC BB:ALRX.OB</strong>), an emerging biopharmaceutical company utilizing proprietary drug delivery technology to develop novel formulations of drugs, today announced that the Company has entered into a collaboration agreement with Venturepharm Group (the 'Venturepharm') to establish a drug development center in China Medical City, Taizhou, China that is expected to be used as a platform for the development of innovative drug products for the fast growing China pharmaceutical market. The goal of this is to enhance the Company's research capabilities, expedite the development of new products as well as to expand the Company's product range.</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;">Under the terms of the agreement, AlphaRx will incorporate its China R D facility into Venturepharm's state of the art pre-clinical development complex which comprises of a 200,000 sq. ft. chemistry center, a 200,000 sq. ft. multi-product pilot plant to support pilot scale formulation and Clinical Trial Material (CTM) manufacture of biopharmaceutical products and a 500,000 sq. ft. (Asia's largest) animal testing center (under construction). The in-house pharmaceutical research facilities provide specialized equipment for most aspects of drug research and development. AlphaRx will be responsible for all of its own product development costs and will in turn retain the intellectual property rights relating to any developed products.</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;">Michael Lee, President of AlphaRx, said: 'Venturepharm provides the equipment and physical infrastructure to further establish our presence in China and reduces our start up investment costs. As AlphaRx continues to build its presence in China, this collaboration with Venturepharm marks an important step in our overall strategy to commercialize current products and to develop new therapeutics for the world fastest growing pharmaceutical market.'</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;"><strong style="">About AlphaRx Inc.</strong></p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;">AlphaRx is a specialty pharmaceutical company dedicated to developing proven therapies by reformulating FDA approved and marketed drugs which through the application of its proprietary site-specific drug delivery technology, offers improved medical benefits and a potential for significant commercial product development.</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;"><strong style="">About Venturepharm group</strong></p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;">Venturepharm Group is an Asia based life science leader that provides world-class, innovative, affordable and integrated service in CRO, CMO and CSO, as well as venture capital, merchant banking for the biotechnological and pharmaceutical industry. Venturepharm also engages in compound licensing, compound partnering and royalty sharing with its clients to expand the market of their products. Venturepharm conducts its business in China as well as global top five markets. The group now operates eight distinct business units with over 2500 employees worldwide.</p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;"><strong style=""><em style="">Forward Looking Statements:</em></strong></p>
<p style="text-align: justify;"> </p>
<p style="text-align: justify;"><em style="">This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the companies.</em></p>
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      <title>[Press Release] AlphaRx Presents Positive Preclinical Data on Zysolin(TM) Inhalable Nanoparticle</title>
      <guid>message_1182777</guid>
      <pubDate>23 Jul 2009 12:00:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/1182777</link>
      <description>
        <![CDATA[<p style="text-align: center;"> </p>
<p style="text-align: center;"><strong><span style="font-size: 14pt; color: #0071bc;">AlphaRx Presents Positive Preclinical Data on Zysolin(TM) Inhalable Nanoparticles at Controlled Release Society Annual Meeting</span></strong></p>
<p><strong>MARKHAM, ON, July 23 - AlphaRx, Inc.</strong> (OTCBB: ALRX) announced positive preclinical results which demonstrated that an inhaled tobramycin nanoparticle (Zysolin(TM)) formulation was a more effective treatment in animal models of acute Pseudomonas aeruginosa pneumonia when compared to inhaled and injected conventional tobramycin solutions. The data was presented recently in an oral podium session at the 36th Annual Meeting and Exposition of the Controlled Release Society inCopenhagen, Denmark.</p>
<p>"These are very encouraging results, as they suggest that Zysolin(TM) employed in this route of administration may be more effective, providing significant advantages over conventional drug formulations," statedJoseph Schwarz , Ph.D., Chief Scientist of AlphaRx. "We believe that building on this data, additional research will lead us toward the development of a drug that targets and eradicates intracellular pathogens, which to date, have proven to be very difficult to treat clinically."</p>
<p>The study results demonstrate that Zysolin(TM) is significantly efficacious in acute pneumonia animal models induced by gram negative pathogens including P. aeruginosa. In these lethality-based studies, Zysolin(TM) consistently increased survival rate to 50% over a Tobramycin treatment group, wherein all untreated animals died within 24 hours after infection. P. aeruginosa is one of the most common and lethal pathogens responsible for ventilator-associated pneumonia in intubated patients, being directly responsible for death rates approaching 40%. This data suggests that the nanoparticulate formulation of Zysolin(TM) may utilize a unique mechanism of action differentiating it from conventional formulations, enhancing antimicrobial activity against gram negative pathogens. Zysolin(TM) has the potential to be a first-in-class anti-infective nanomedicine.</p>
<p>The Controlled Release Society (CRS) is an international organization consisting of 3,000 members from more than fifty countries. Two-thirds of CRS membership are from the pharmaceutical industry and one-third consist of academic and government members. The CRS is the premier multidisciplinary society dedicated to the promotion of the science, technology, and innovative delivery of bio-actives for the benefit of the society.</p>
<p><strong> </strong></p>
<p><strong>About Zysolin(TM)</strong></p>
<p>Zysolin(TM) is a Tobramycin compound, encapsulated in AlphaRx's Nano Drug Delivery Platform, intended for the adjunctive treatment of Gram-negative pneumonia in intubated and mechanically-ventilated patients. Zysolin(TM) improves the intracellular activity of Tobramycin - in layman's term, increasing the drug concentration of Tobramycin inside human macrophages, thus improving its antibacterial activity against intracellular Klebsiella, Pseudomondas aeruginosa and Staphylococcus bacterial strains in pneumonia patients. The active ingredient in Zysolin(TM), Tobramycin, has a long-standing and proven clinical treatment record. Delivered by inhalation, using proprietary nanotechnology developed by AlphaRx, the company believes Zysolin(TM) will have an attractive safety, tolerability and efficacy profile when compared to injectible Tobramycin.</p>
<p><strong>About AlphaRx Inc.</strong></p>
<p>AlphaRx is a specialty pharmaceutical company dedicated to developing proven therapies by reformulating FDA approved and marketed drugs which through the application of its proprietary site-specific nano drug delivery technology, offers improved medical benefits and a potential for significant commercial product development.</p>
<p><strong><em>Forward Looking Statements:</em></strong></p>
<p><em>This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the companies.</em></p>
<p>SOURCE AlphaRx Inc.</p>
<p>For further information: AGORACOM Investor Relations Corp., <a href="mailto:ALRX@Agoracom.com" target="_blank">ALRX@Agoracom.com</a>, <a href="http://www.agoracom.com/" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"><a href="http://www.agoracom.com" target="_blank">http://www.agoracom.com</a></a></p>]]>
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      <title>[Press Release] AlphaRx Unveils its China Strategy</title>
      <guid>message_1180843</guid>
      <pubDate>21 Jul 2009 12:55:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/1180843</link>
      <description>
        <![CDATA[<p style="line-height: normal;"><span>AlphaRx plans to open an R&amp;D facility and manufacturing plant in China w</span><span>ith local partners, to introduce innovative drug products to the fastest </span><span>growing pharmaceutical market in the world.</span></p>
<p style="line-height: normal;"> </p>
<p style="line-height: normal;"><span>MARKHAM, ON, July 21 - AlphaRx (OTC BB:ALRX), an emerging biopharmaceutical company, utilizing proprietary drug delivery technology to develop novel formulations of drugs, is forging ahead with its growth strategy for Greater China. As part of this strategy, AlphaRx is poised to open a 'state of the art' R D and pilot plant facility in China with local partners. The R D facility will focus on the development of innovative drug products targeting infectious disease and various forms of cancer. Additionally, the Company, together with its local partners, plans to develop adjuvant vaccines to treat influenza, such as H5N1 and H1N1 strains.</span></p>
<p style="line-height: normal;"><span>AlphaRx currently has a topical NSAID awaiting near-term registration in China and is developing a second product - GAI-122 - an injectable nanoemulsion, in collaboration with Gaia BioPharma for the treatment of acute hepatitis, a therapy with a multi-million dollar potential indication in China.</span></p>
<p style="line-height: normal;"><span>The Chinese government has been a strong supporter of the life sciences industry. It plans to further increase its investment in the sector through a variety of grants and awards in some of its leading science and technology parks and through the National Program 863, originally established in March 1983 by Deng Xiaoping to award grants to science and technology projects that have significant commercial value. Most notably, in November 2008, China launched the Mega New Drug Development Program, a plan to invest $10 billion over the next 13 years, with the aim of creating a China-based innovative drug development industry.</span></p>
<p style="line-height: normal;"><span>About AlphaRx Inc.</span></p>
<p style="line-height: normal;"><span>AlphaRx is a specialty pharmaceutical company dedicated to developing proven therapies by reformulating FDA approved and marketed drugs which through the application of its proprietary site-specific nano drug delivery technology, offers improved medical benefits and a potential for significant commercial product development.</span></p>
<p style="line-height: normal;"><span>Forward Looking Statements:</span></p>
<p style="line-height: normal;"><span>This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the companies.</span></p>]]>
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      <title>[Press Release] AlphaRx Reports Positive Preclinical Data on GAI-122 Against Liver Disease</title>
      <guid>message_1172129</guid>
      <pubDate>08 Jul 2009 12:00:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/1172129</link>
      <description>
        <![CDATA[<p><strong><em>GAI-122, an investigational injectable nano-emulsion formulated with AlphaRx's proprietary drug delivery technology, provides significant hepatoprotection in multiple animal models of acute hepatitis suggesting that GAI-122 may reduce necro-inflammation and may halt disease progression to fibrosis or cirrhosis.</em></strong></p>
<p><strong>MARKHAM, ON, July 8 - AlphaRx Inc.</strong> (OTCBB: ALRX) today reported positive preclinical results on GAI-122 injectable nano-emulsion in multiple models of acute hepatitis, an inflammatory liver disease.</p>
<p>GAI-122 significantly reduced Aminotransferase (ALT), an enzyme released into the blood that indicates damage to the liver, following IP administration in three different preclinical models of acute liver injury. Very high levels of ALT are usually due to acute hepatitis or a viral infection.</p>
<p>In the a-Fas model of liver injury, GAI-122 markedly reduced ALT levels by 90% from baseline, where control ALT values were ~22,000 IU/L. Significant efficacy was also demonstrated in the rat TNFa/Gln model and in the Drug-induced liver injury (DILI) model.</p>
<p>"DILI accounts for more than 50% of acute liver failure and there are no satisfactory treatment options currently available. The excellent efficacy data demonstrated by these studies suggest that GAI-122 may represent a potential first line treatment option for patients with liver disease", stated Dr.Michael Weisspapir, MD, PhD, Chief Medical Scientist of AlphaRx.</p>
<p>In October 2008, AlphaRx licensed GAI-122 to Gaia BioPharma. Under the terms of the amended agreement, AlphaRx is eligible to receive milestone payments of up to$50 million for the successful development and commercialization of GAI-122, as well as royalties on worldwide sales. In addition, Gaia BioPharma has assumed all development costs.</p>
<p><strong>About AlphaRx Inc.</strong></p>
<p>AlphaRx is a specialty pharmaceutical company dedicated to developing proven therapies by reformulating FDA approved and marketed drugs which through the application of its proprietary site-specific nano drug delivery technology, offers improved medical benefits and a potential for significant commercial product development.</p>
<p><strong>About Gaia BioPharma</strong></p>
<p>Gaia BioPharma Limited, a privately held, early stage biopharmaceutical company focused on hospital-based injectable therapeutics. Gaia BioPharma seeks to address key unmet therapeutic needs by taking established compounds and changing their administration routes to create patent-protected, value-added products.</p>
<p><strong><em>FORWARD LOOKING STATEMENTS:</em></strong><em><br />This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the Company.</em></p>]]>
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      <title>[Press Release] AlphaRx And Gaia Biopharma Report Positive Efficacy Results In A Pre-Clinical...</title>
      <guid>message_1167931</guid>
      <pubDate>29 Jun 2009 12:00:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/1167931</link>
      <description>
        <![CDATA[<h3><strong><span style="color: #3366ff;">AlphaRx And Gaia Biopharma Report Positive Efficacy Results In A Pre-Clinical Trial Of Gai-122 Injectable Nano-Emulsion For Post-Operative Delirium</span></strong></h3>
<p><strong><em>GAI-122, an investigational injectable nanoemulsion formulated with AlphaRx's proprietary drug delivery technology, providing significant neuro-protection in multiple in vitro and in vivo studies which suggest that this injectable nanoemulsion formulation has the potential to prevent postoperative delirium.</em></strong></p>
<p><strong>MARKHAM, ON, June 29 - AlphaRx Inc. (OTCBB: ALRX) </strong>and Gaia BioPharma Limited today reported positive pre-clinical results on GAI-122 injectable nanoemulsion in multiple in vitro and in vivo studies of memory impairment after prolonged anesthesia.</p>
<p>Delirium is a common mental disorder with serious adverse outcomes in post-operative hospitalized patients. It is associated with an increase in mortality, physical morbidity, length of hospital stay, institutionalization of patients and increased cost to healthcare providers. Ten to thirty percent of admissions of patients over 65 years of age to a general hospitals develop delirium after surgery and the incidence rate can be as high as 50% in patients who undergone high risk and lengthy procedures such as hip replacement and cardiac surgeries. There is no preventive therapy currently available for post-operative delirium.</p>
<p>"There are over 10,000,000 inpatient surgeries performed annually in the U.S. on patients over the age of 65, and up to 40% of these seniors will develop post-operative delirium. There is an urgent need to develop a medicine, such as GAI-122 injectable nanoemulsion, for the preventive of this debilitating post-operative condition," said Dr.Michael Weisspapir, MD, PhD, Chief Medical Scientist of AlphaRx.</p>
<p>In rat model studies, injected GAI-122 ameliorates learning and memory disturbances produced by cerebral embolization, cerebral ischemia or lesions in the basal forebrain, the area of origin of the acetylcholine neuron system projecting into the cerebral cortex, hippocampus and amygdala. In clinical tests, an oral form of GAI-122 has been shown to be effective in psychological deficits such as a decline in memory retention and disorientation.</p>
<p>In October 2008, AlphaRx licensed GAI-122 to Gaia BioPharma. Under the terms of the amended agreement, AlphaRx is eligible to receive milestone payments of up to$50 million for the successful development and commercialization of GAI-122, as well as royalties on worldwide sales. In addition, Gaia BioPharma has assumed all development costs.</p>
<p><strong>About AlphaRx Inc.</strong></p>
<p>AlphaRx is a specialty pharmaceutical company dedicated to developing proven therapies by reformulating FDA approved and marketed drugs which through the application of its proprietary site-specific nano drug delivery technology, offers improved medical benefits and a potential for significant commercial product development.</p>
<p><strong>About Gaia BioPharma</strong></p>
<p>Gaia BioPharma Limited, a privately held, early stage biopharmaceutical company focused on hospital-based injectable therapeutics. Gaia BioPharma seeks to address key unmet therapeutic needs by taking established compounds and changing their administration routes to create patent-protected, value-added products.</p>
<p><em><strong>FORWARD LOOKING STATEMENTS:</strong></em></p>
<p><em>This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the Company.</em></p>
<p>SOURCE  AlphaRx Inc.</p>
<p>For further information:<br />AGORACOM Investor Relations Corp.<br /><a href="mailto:ALRX@Agoracom.com" target="_blank">ALRX@Agoracom.com</a><br /><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"><a href="http://www.agoracom.com" target="_blank">http://www.agoracom.com</a></a></p>]]>
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      <title>[Press Release] AlphaRx Shareholder Update</title>
      <guid>message_1163916</guid>
      <pubDate>24 Jun 2009 12:00:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/1163916</link>
      <description>
        <![CDATA[<p>MARKHAM, ON, June 24 /PRNewswire-FirstCall/ - AlphaRx Inc. (OTCBB: ALRX) releases letter to their shareholders:</p>

<p>Dear Shareholders,</p>

<p>We wanted to take a few minutes to update the current views on AlphaRx. For the first time in our corporate history, we ended our last quarter with a small profit. Aside from the fact that it was a small amount, it was significant on more than one front. The events that occurred over the past few weeks, have woke up investors around the world.</p>
<p>Our revenue is growing and our product pipeline remains robust and stronger than ever. We have 2 partnered products with potential milestone payments in excess of US$ 155 million which may generate a long-term stream of multi-million dollar royalty income. We at AlphaRx, have established research collaborations with leading specialty pharmaceutical companies and research institutions, such as the US Army. We have both benefited either financially or scientifically. Furthermore, these collaborations may lead to licensing agreements of our products.</p>
<p>We are in the forefront of nanomedicine development and we are poised to be the world's first pharmaceutical company to commercialize a polymeric-based nanomedicine for the treatment of nosocomial pneumonia.</p>
<p>Our goal, as it has been from Day number one, is to create profit for our shareholders and increase shareholder value. We believe we are succeeding. Thank you for your support. We will continue to keep you informed.</p>

<pre>    Michael M. Lee

    President &amp; CEO
</pre>

<p>About AlphaRx Inc.</p>

<p>AlphaRx is a specialty pharmaceutical company dedicated to developing proven therapies by reformulating FDA approved and marketed drugs which through the application of its proprietary site-specific nano drug delivery technology, offers improved medical benefits and a potential for significant commercial product development.</p>

<p>FORWARD LOOKING STATEMENTS:</p>

<p>This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the Company.</p>]]>
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      <title>[Press Release] Zysolin(Tm) Pre-Clinical Data Supports Once-A-Day Dosing In Humans</title>
      <guid>message_1167923</guid>
      <pubDate>18 Jun 2009 12:00:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/1167923</link>
      <description>
        <![CDATA[<div>
<pre><em><strong><br />AlphaRx's inhaled Tobramycin nanoparticle formulation provides 300% more <br />availability than standard free drug in lung tissue, as demonstrated in a recent <br />animal pharmacokinetic study.</strong></em><br /><br /><br /></pre>
<p><strong>MARKHAM, ON, June 18 - AlphaRx (OTC BB:ALRX)</strong> is pleased to report a significant breakthrough in the development of Zysolin(TM), an inhaled Tobramycin nanoparticle formulation utilizing the company's proprietary drug delivery platform, and intended for the adjunctive treatment of Pseudomonas Aeruginosa Pneumonia in intubated and mechanically-ventilated patients (VAP).</p>
<p>In a recent pivotal animal PK (pharmacokinetic) study, Zysolin(TM) delivered 300% more drug to lung tissue than free drug, when utilizing the same delivery method. This data demonstrates that Zysolin(TM) provides superior lung tissue penetration and a release profile which supports once-a-day human dosing frequency.</p>
<p>The study data will be presented, by invitation, to the upcoming July meeting of the Controlled Release Society Conference in Copenhagen, Denmark.</p>
<p>Dr. Michael Weisspapir, MD, PhD, Chief Medical Scientist of AlphaRx commented, "As a result of this pre-clinical data, we anticipate that the demonstrated superiority over free drug availability will result in higher drug concentrations in lung tissue, enhancing clinical efficacy for VAP patients in vivo."</p>
<p><strong>About Zysolin(TM)</strong></p>
<p>Zysolin(TM) is a Tobramycin compound, encapsulated in AlphaRx's Nano Drug Delivery Platform, intended for the adjunctive treatment of Gram-negative pneumonia in intubated and mechanically-ventilated patients. Zysolin(TM) improves the intracellular activity of Tobramycin - in layman's term, increasing the drug concentration of Tobramycin inside human macrophages, thus improving its antibacterial activity against intracellular Klebsiella, Pseudomondas aeruginosa and Staphylococcus bacterial strains in pneumonia patients. The active ingredient in Zysolin(TM), Tobramycin, has a long-standing and proven clinical treatment record. Delivered by inhalation, using proprietary nanotechnology developed by AlphaRx, the company believes Zysolin(TM) will have an attractive safety, tolerability and efficacy profile when compared to injectible Tobramycin.</p>
<p><strong>About AlphaRx Inc.</strong></p>
<p>AlphaRx is a specialty pharmaceutical company dedicated to developing proven therapies by reformulating FDA approved and marketed drugs which through the application of its proprietary site-specific nano drug delivery technology, offers improved medical benefits and a potential for significant commercial product development.</p>
<p><em><strong>Forward Looking Statements:</strong></em></p>
<p><em>This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the companies.</em></p>
<p>SOURCE  AlphaRx Inc.</p>
<p>For further information:<br />AGORACOM Investor Relations Corp.<br /><a href="mailto:ALRX@Agoracom.com" target="_blank">ALRX@Agoracom.com</a><br /><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"></a><a href="http://www.agoracom.com" target="_blank"><a href="http://www.agoracom.com" target="_blank">http://www.agoracom.com</a></a></p>
</div>]]>
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      <title>[Press Release] AlphaRx and Gaia BioPharma Provide GAI-122 Development Update</title>
      <guid>message_1158925</guid>
      <pubDate>16 Jun 2009 08:35:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/1158925</link>
      <description>
        <![CDATA[<p><strong><em>GAI-122, an investigational injectable nano-emulsion formulated with AlphaRx's proprietary drug delivery technology, provides significant neuroprotection in animal behavioral models. Gaia BioPharma plans to initiate a clinical development program to further study GAI-122 for an acute and as yet, unmet neurological indication.</em></strong></p>
<p><strong>MARKHAM, ON, June 16, 2009 -- AlphaRx Inc. (OTCBB: ALRX) </strong>and Gaia BioPharma Limited, a privately held, early stage biopharmaceutical company focused on hospital-based injectable therapeutics, are pleased to provide a progress report on GAI-122.</p>
<p>GAI-122 offers significant and direct neuroprotection in both in vitro and in vivo ischemic conditions. Experimental evidence suggests that the neuroprotective action of GAI-122 is related to its' active inhibition of apoptosis or cell death. GAI-122 shows potential as a major treatment innovation in the management of ischemic neurological disorders such as stroke and traumatic brain injury.</p>
<p>The proposed initial indication for GAI-122 is an acute neurological disorder affecting millions of patients undergoing cardiac and hip replacement surgery. It is estimated that the market potential for this unmet indication exceeds US$2 billion a year.</p>
<p>GAI-122 is in the final stage of formulation optimization, which is expected to be completed by the end of summer 2009, proceeding to clinical trial materials manufacturing thereafter. GAI-122 is protected by 4 US patent applications.</p>
<p>In October 2008, AlphaRx licensed GAI-122 to Gaia BioPharma. Under the terms of the amended agreement, AlphaRx is eligible to receive milestone payments of up to $50 million for the successful development and commercialization of GAI-122, as well as royalties on worldwide sales. In addition, Gaia BioPharma has assumed all development costs.</p>
<p><strong>About AlphaRx Inc. </strong></p>
<p>AlphaRx is a specialty pharmaceutical company dedicated to developing proven therapies by reformulating FDA approved and marketed drugs which through the application of its proprietary site-specific nano drug delivery technology, offers improved medical benefits and a potential for significant commercial product development.</p>
<p><strong>About Gaia BioPharma </strong></p>
<p>Gaia BioPharma Limited, a privately held, early stage biopharmaceutical company focused on hospital-based injectable therapeutics. Gaia BioPharma seeks to address key unmet therapeutic needs by taking established compounds and changing their administration routes to create patent-protected, value-added products.</p>
<p><em><strong>FORWARD LOOKING STATEMENTS: </strong></em></p>
<p><em>This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the Company. </em></p>]]>
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      <title>[Industry Bulletin] Market Post Strong Weekly Gains</title>
      <guid>message_1015203</guid>
      <pubDate>28 Nov 2008 14:30:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/1015203</link>
      <description>
        <![CDATA[<div>
<p>Stocks ended higher Friday, leaving the market with monthly losses but posting strong gains in a holiday-shortened week that saw investors increasingly confident that much of a dire economic outlook is already priced in. The Dow Jones Industrial Average gained 102 points, or 1.2%, at 8,829, with 23 of its 30 components ending higher. For the week, the blue-chip average jumped 9.2%.</p>
<p><img src="http://ichart.finance.yahoo.com/w?s=%5EDJI" /></p>
<br /><br />
<p>The S&amp;P 500 index rose 8 points, or 1%, to 896. The broad index gained 12% for the week &amp; is up an astounding 144pts (16%) from Friday's intraday lows.</p>
<p><img src="http://ichart.finance.yahoo.com/w?s=%5EGSPC" height="288" width="512" /></p>
<br /><br />
<p>The Nasdaq Composite    gained 3 points, or 0.2%, to 1,535. The technology-heavy index jumped 11% for the week.</p>
<p><img src="http://ichart.finance.yahoo.com/w?s=%5EIXIC" height="288" width="512" /></p>
<br /><br />
<p>In Toronto, the Toronto Stock Exchange shook off a sluggish opening to extend gains for a 6th straigh session. As of 1:38 pm, the composite index added 213 pts, or 2.44%, on the strength of consumer staples and financial stocks.</p>
<p style="text-align: center;"><img src="http://www.tsx.com/en/images/charts/newtsehome_volume.gif?610022" height="20" width="217" /></p>
<p style="text-align: center;"><img src="http://www.tsx.com/en/images/charts/tse300.gif?246078" height="155" width="265" /></p>
<p style="text-align: center;"><img src="http://www.tsx.com/en/images/charts/tse300_footer.gif?246078" /></p>
<p style="text-align: left;"> </p>
<p style="text-align: left;">Meanwhile, the TSX Venture Exchange gained 8.82 pts to 757.05, a 53 pt increase on the week.</p>
<p style="text-align: center;"><img src="http://www.tsx.com/en/images/charts/newcdnxhome_volume.gif?610022" /></p>
<p style="text-align: center;"><img src="http://www.tsx.com/en/images/charts/sp_cdnx.gif?246078" height="147" width="253" /></p>
<p style="text-align: center;"><img src="http://www.tsx.com/en/images/charts/sp_cdnx_footer.gif?246078" /></p>
<p style="text-align: left;"> </p>
<p style="text-align: left;">As you've seen through our industry bulletins, George's blog (<a href="http://blog.agoracom.com/" target="_blank">http://blog.agoracom.com/</a>) and Peter Grandich's commentary on gold (<a href="http://grandich.agoracom.com/" target="_blank">http://grandich.agoracom.com/</a>), AGORACOM is not surprised by the snap-back rally this week, and in particular the strength in gold stocks. AGORACOM continues to believe there is long term value in the market, and encourages everyone purchasing shares to utilize our online hubs in your due diligence activity.</p>
</div>]]>
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      <title>[Press Release] NEWS - AlphaRx and Gaia BioPharma Enter Into Feasibility and Option Agreement</title>
      <guid>message_981393</guid>
      <pubDate>22 Oct 2008 08:03:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/981393</link>
      <description>
        <![CDATA[<pre><strong><em>    Gaia seeks to address key unmet therapeutic needs by taking established<br />    compounds and changing their administration routes to create patent-<br />    protected, value-added products using AlphaRx's proprietary nano drug<br />    delivery technologies</em></strong><br /><br /></pre>
<p><strong>MARKHAM, ON, Oct. 22 - AlphaRx Inc. (OTCBB: <a href="http://ca.finance.yahoo.com/q?s=ALRX.OB" target="_blank">ALRX.OB</a>)</strong> and Gaia BioPharma Limited, a privately held, early stage biopharmaceutical company focused on hospital-based injectable therapeutics, today announced the signing of a Feasibility and Option Agreement.</p>
<p>Under the terms of the Agreement, AlphaRx will use its proprietary nano drug delivery platforms to formulate two injectable products targeting underserved medical conditions. These represent market opportunities potentially exceeding US$200M in annual revenue for Gaia. Gaia will have 12 months to evaluate the formulated products and exercise its option right for a pre-negotiated License Agreement.</p>
<p>AlphaRx is responsible for completing the product development work and will be eligible to receive an upfront non-refundable option fee and reimbursements in exchange for completing certain pre-defined development milestones. AlphaRx will also receive royalty and milestone payments from future product sales that utilize AlphaRx's delivery technology. Gaia BioPharma will be responsible for performing all aspects of clinical development, regulatory submission, manufacture and commercial operations.</p>
<p>The licensing agreements include up to US$5.35M to AlphaRx in potential development milestone payments; potential sales milestones in excess of US$27M in addition to royalties on the net sales of the two products by Gaia. The first product is expected to reach commercial stage by 2011.</p>
<p><strong>About AlphaRx Inc.</strong></p>
<p>AlphaRx is a specialty pharmaceutical company dedicated to developing proven therapies by reformulating FDA approved and marketed drugs which through the application of its proprietary site-specific nano drug delivery technology, offers improved medical benefits and a potential for significant commercial product development.</p>
<p><strong>FORWARD LOOKING STATEMENTS:</strong></p>
<p>This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the Company.</p>
<p><strong>For more information, please contact:</strong><br /><br />AGORACOM Investor Relations Corp.<br /> Web: <a href="http://www.agoracom.com//" target="_blank"><strong>http://www.agoracom.com</strong></a> <br /> E-mail: <a href="mailto:ALRX@Agoracom.com" target="_blank"><strong>ALRX@Agoracom.com</strong></a></p>]]>
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      <title>[Press Release] NEWS - AlphaRx Appoints Leading Infectious Disease Specialist to Its Scientific Advisory Board</title>
      <guid>message_942333</guid>
      <pubDate>17 Sep 2008 08:01:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/942333</link>
      <description>
        <![CDATA[<p><strong>MARKHAM, ON, Sept. 17 - AlphaRx Inc. (OTCBB: <a href="http://ca.finance.yahoo.com/q?s=ALRX.OB" target="_blank">ALRX.OB</a>) </strong>is pleased to announce the appointment of Dr. Donald Low to its Scientific Advisory Board (SAB), effective immediately. With more than 30 years of experience, Dr. Low is recognized world-wide as an authority in the area of emerging infectious diseases.</p>
<p>Dr. Low is currently Head the Division of Microbiology, Department of Laboratory Medicine and Pathobiology at the University of Toronto in Toronto, Ontario. He is also Chief of University Health Network and Mount Sinai Hospital Department of Microbiology, as well as Professor for the Departments of Microbiology and Medicine at the University of Toronto. In addition, Dr. Low is Medical Director of the Public Health Laboratories for the Ontario Ministry of Health and Long-Term Care.</p>
<p>Dr. Low brings with him years of research experience in infectious diseases, particularly in new drug investigation, clinical trials design and implementation. The Scientific Advisory Board (SAB) will be instrumental in implementing AlphaRx's goal of advancing its lead pharmaceutical product Zysolin(TM) through clinical development.</p>
<p><strong>About Zysolin(TM)</strong></p>
<p>Zysolin(TM) is a Tobramycin compound, encapsulated in AlphaRx's Nano Drug Delivery Platform, intended for the adjunctive treatment of Gram-negative pneumonia in intubated and mechanically-ventilated patients. Zysolin(TM) improves the intracellular activity of Tobramycin - in layman's term, increasing the drug concentration of Tobramycin inside human macrophages, thus improving its antibacterial activity against intracellular Klebsiella, Pseudomondas aeruginosa and Staphylococcus bacterial strains in pneumonia patients. The active ingredient in Zysolin(TM), Tobramycin, has a long-standing and proven clinical treatment record. Delivered by inhalation, using proprietary nanotechnology developed by AlphaRx, the company believes Zysolin(TM) will have an attractive safety, tolerability and efficacy profile when compared to injectable Tobramycin.</p>
<p><strong>About AlphaRx Inc.</strong></p>
<p>AlphaRx is a specialty pharmaceutical company dedicated to developing proven therapies by reformulating FDA approved and marketed drugs which through the application of its proprietary site-specific nano drug delivery technology, offers improved medical benefits and a potential for significant commercial product development.</p>
<p><strong>FORWARD LOOKING STATEMENTS:</strong></p>
<p>This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the Company.</p>]]>
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      <title>[Press Release] NEWS - AlphaRx Receives Conditional Approval to List on the TSX Venture Exchange</title>
      <guid>message_908246</guid>
      <pubDate>12 Aug 2008 08:00:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/908246</link>
      <description>
        <![CDATA[<p><strong>MARKHAM, ON, Aug. 12 -- AlphaRx (OTC BB:<a href="http://finance.yahoo.com/q?s=alrx.ob&amp;d=t" target="_blank">ALRX</a>)</strong> AlphaRx, a leader in the development of Nanotechnology for Drug Delivery Platforms, is pleased to announce that it has received conditional approval from the TSX Venture Exchange to list the common shares of the Company on the Exchange. Listing of the common shares on the TSX Venture Exchange is subject to compliance with all conditions of the Exchange, including receipt of all required documentation. AlphaRx intends to fulfill the listing conditions as soon as its practical.</p>
<p><strong>About AlphaRx Inc.</strong></p>
<p>AlphaRx is a specialty pharmaceutical company dedicated to developing proven therapies by reformulating FDA approved and marketed drugs which through the application of its proprietary site-specific nano drug delivery technology, offers improved medical benefits and a potential for significant commercial product development.</p>
<p><strong>Forward Looking Statements:</strong></p>
<p>This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the companies.</p>
<br /><br />
<p><strong>For more information, please contact:</strong></p>
<p>AGORACOM Investor Relations Corp.<br />Web: <a href="http://www.agoracom.com/ir/alpharx" target="_blank"><strong>http://www.agoracom.com</strong></a> <br /> E-mail: <a href="mailto:ALRX@Agoracom.com" target="_blank"><strong>ALRX@Agoracom.com</strong></a></p>]]>
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      <title>[Press Release] NEWS - Zysolin(TM) Improves Survival in Pivotal Animal Studies</title>
      <guid>message_870127</guid>
      <pubDate>26 Jun 2008 10:39:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/870127</link>
      <description>
        <![CDATA[<p><strong><span>AlphaRx's inhaled Tobramycin nanoparticles demonstrated superior therapeutic efficacy in mouse models of acute Pseudomonas aeruginosa pneumonia. Zysolin(TM) could be a first-in-class anti-infective nanomedicine</span></strong></p>
<p><strong>MARKHAM, ON, June 26 - AlphaRx (OTC BB:<a href="http://finance.yahoo.com/q?s=alrx.ob&amp;d=t" target="_blank">ALRX</a>) </strong>is pleased to report additional pre-clinical data on Zysolin(TM), an inhaled Tobramycin nanoparticles intended for the adjunctive treatment of Pseudomonas aeruginosa pneumonia in intubated and mechanically-ventilated patients (VAP). Injectible Tobramycin is the drug of choice used in the initial empirical therapy for VAP and is also well known for its nephrotoxicity. Zysolin(TM) is intended to replace injectible Tobramycin in VAP therapy. AlphaRx believes Zysolin(TM) will have an attractive safety, tolerability and efficacy profile in comparison to injectible Tobramycin.</p>
<p>Zysolin(TM) has demonstrated superior therapeutic efficacy in 2 pivotal animal studies. In these lethality-based studies, Zysolin(TM) has consistently increased survival rate by 50% over Tobramycin treatment group whereby all mice in the untreated group died within 24 hours after infection.</p>
<p>"P. aeruginosa is one of the most common and lethal pathogens responsible for ventilator-associated pneumonia in intubated patients, with directly attributable death rates reaching 40%. "Reducing this mortality rate may be possible, if a more effective therapy for the treatment of Pseudomonas VAP can be developed," said Dr. Michael Weisspapir, MD, PhD, Chief Medical Scientist of AlphaRx. "If approved, Zysolin(TM) could be a first-in-class cell-targeted nanomedicine which is designed to target intracellular pathogens that have proven to be very difficult to eradicate clinically," further commented by Dr. Weisspapir.</p>
<p>AlphaRx is working with regulatory experts to devise a clinical plan for Zysolin(TM) with a view to initiating Phase I human trials in early 2009. AlphaRx believes Zysolin(TM) may be eligible for an NDA submission under the 505(b)(2) regulatory pathway, which permits companies to obtain FDA approval of new drug applications (NDAs) by relying, in part, on the agency's findings for a previously approved drug. AlphaRx can potentially advance Zysolin(TM) rapidly through clinical testing and to commercialization using the 505(b)(2) pathway.</p>
<p><strong>About Zysolin(TM)</strong></p>
<p>Zysolin(TM) is a Tobramycin compound, encapsulated in AlphaRx's Nano Drug Delivery Platform, intended for the adjunctive treatment of Gram-negative pneumonia in intubated and mechanically-ventilated patients. Zysolin(TM) improves the intracellular activity of Tobramycin - in layman's term, increasing the drug concentration of Tobramycin inside human macrophages, thus improving its antibacterial activity against intracellular Klebsiella, Pseudomondas aeruginosa and Staphylococcus bacterial strains in pneumonia patients. The active ingredient in Zysolin(TM), Tobramycin, has a long-standing and proven clinical treatment record. Delivered by inhalation, using proprietary nanotechnology developed by AlphaRx, the company believes Zysolin(TM) will have an attractive safety, tolerability and efficacy profile when compared to injectible Tobramycin.</p>
<p><strong>About AlphaRx Inc.</strong></p>
<p>AlphaRx is a specialty pharmaceutical company utilizing proprietary site-specific nanoparticulate drug delivery systems to develop novel formulations of drugs that are insoluble or poorly soluble in water or have yet to be administrable to the human body with an acceptable delivery method.</p>
<p><strong>Forward Looking Statements:</strong></p>
<p>This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the companies.</p>
<p><strong>For more information, please contact:</strong><br /><br />AGORACOM Investor Relations Corp.<br /> Web: <a href="../../../..//" target="_blank"><strong>http://www.agoracom.com</strong></a> <br /> E-mail: <a href="mailto:ALRX@Agoracom.com" target="_blank"><strong>ALRX@Agoracom.com</strong></a></p>]]>
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      <title>[Press Release] NEWS - Zysolin Shows Promising Results in Animal Study</title>
      <guid>message_849709</guid>
      <pubDate>03 Jun 2008 08:05:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/849709</link>
      <description>
        <![CDATA[<p><strong>    MARKHAM, ON, June 3 - AlphaRx (OTC BB: <a href="http://ca.finance.yahoo.com/q?s=ALRX" target="_blank">ALRX</a>)</strong> is pleased to announce pre-clinical data on Zysolin(TM), a Tobramycin compound encapsulated in the company's Nano Drug Delivery Platform intended for the treatment of Cystic Fibrosis and an adjunctive treatment of Gram-negative pneumonia in intubated and mechanically-ventilated patients.</p>  <p>    In the recent animal study, the therapeutic efficacy of Zysolin was investigated in a mouse model of Pseudomonas aeruginosa pneumonia. In this acute model, pneumonia developed rapidly, resulting in a high mortality rate, no mice survived after 24 hours of infection without treatment. Mice treated with Zysolin(TM) showed significantly better efficacy than Tobramycin, achieving 60% survival rate vs. 40% in the Tobramycin treatment group. An increase of survival by 50% or more, relative to vehicle control, indicates significant anti-microbial effect. The Tobramycin treatment group did not meet the study's end point.</p>  <p>    Pseudomonas aeruginosa is a major cause of lung infections, particularly nosocomial pneumonia. Mortality rates of patients with P. aeruginosa pneumonia are higher than the mortality rates of patients with pneumonia caused by other pathogens because P. aeruginosa pneumonia frequently disseminates to cause bacteremia and sepsis. Currently, Gram-negative pneumonia carries a mortality risk as high as 50 percent in mechanically-ventilated patients.</p>   <p><strong>    About AlphaRx Inc.</strong></p>   <p>    AlphaRx is a specialty pharmaceutical company utilizing proprietary site-specific nanoparticulate drug delivery systems to develop novel formulations of drugs that are insoluble or poorly soluble in water or have yet to be administrable to the human body with an acceptable delivery method.</p>   <p><strong>    Forward Looking Statements:</strong></p>   <p>    This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the companies.</p>  <p><strong>For more information, please contact:</strong><br /><br />AGORACOM Investor Relations Corp.<br /> Web: <a href="http://www.agoracom.com//" target="_blank"><strong>http://www.agoracom.com</strong></a> <br /> E-mail: <a href="mailto:ALRX@Agoracom.com" target="_blank"><strong>ALRX@Agoracom.com</strong></a></p>]]>
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      <title>[Press Release] NEWS - AlphaRx Signs Cooperative Research and Development Agreement with US Army</title>
      <guid>message_841414</guid>
      <pubDate>27 May 2008 08:01:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/841414</link>
      <description>
        <![CDATA[<p><strong>    MARKHAM, ON, May 27 - AlphaRx (OTC BB:ALRX)</strong>, an emerging biopharmaceutical company utilizing proprietary drug delivery technology to develop novel formulations of drugs, is pleased to report that AlphaRx and USAMRIID (U.S. Army Medical Research Institute of Infectious Diseases) has entered into a Cooperative Research and Development Agreement for Material Transfer (MTA). The resulting joint R&amp;D effort enables USAMRIID scientists to test the efficacy of AlphaRx's &quot;nanobiotics&quot; for the treatment of severe intracellular bacterial infections caused by Category A pathogens in animal models. Category A pathogens are organisms classified by US Government used mainly in biological weapons that pose a risk to national security.</p>  <p>    The MTA covers several &quot;nanobiotics&quot; including Ciprofloxacin, Doxycycline and Gentamicin developed by AlphaRx. These are the usual antibiotics used to treat patients in a bioterrorism event. However, they all show limited efficacy clinically. AlphaRx believes that their specially-formulated version of these antibiotics provides improved intracellular activity in animal studies and may have better clinical efficacy.</p>  <p>    AlphaRx is excited with the opportunity to work with the U.S. Army. It opens up a non-commercial application to AlphaRx's drug development programs, with the potential to be a provider to the national stockpile program, through Project Bioshield.</p>   <p><strong>    About AlphaRx Inc.</strong></p>   <p>    AlphaRx is a specialty pharmaceutical company utilizing proprietary site-specific nanoparticulate drug delivery systems to develop novel formulations of drugs that are insoluble or poorly soluble in water or have yet to be administrable to the human body with an acceptable delivery method. The Company's product candidates address various pharmaceutical markets, including inflammation, tuberculosis and pneumonia.</p>   <p><strong>    Forward Looking Statements:</strong></p>   <p>    This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the companies.</p><p><strong>For more information, please contact:</strong><br /><br />AGORACOM Investor Relations Corp.<br /> Web: <a href="http://www.agoracom.com//" target="_blank"><strong>http://www.agoracom.com</strong></a> <br /> E-mail: <a href="mailto:ALRX@Agoracom.com" target="_blank"><strong>ALRX@Agoracom.com</strong></a></p>  <br /><br />]]>
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      <title>[Press Release] NEWS - AlphaRx Provides Corporate and Development Update</title>
      <guid>message_835191</guid>
      <pubDate>20 May 2008 08:01:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/835191</link>
      <description>
        <![CDATA[<p><strong>    MARKHAM, ON, May 20 - AlphaRx (OTC BB:ALRX)</strong>, an emerging biopharmaceutical company utilizing proprietary drug delivery technology to develop novel formulations of drugs, is pleased to provide shareholders with an update on recent corporate developments.<br /></p>     <p><strong>    TSX Venture Exchange Application</strong><br />--------------------------------<br /></p>  <p>    AlphaRx is seeking a listing with the TSX Venture Exchange. Research Capital Corporation is sponsoring the application. AlphaRx is in the process of raising up to $1,800,000 U.S. via a private placement in conjunction with the listing application. AlphaRx has been in correspondence with the TSX Venture Exchange and has responded to all comments raised to-date.<br /></p>     <p><strong>    Corporate Website</strong><br />-----------------<br /></p>  <p>    AlphaRx is working on a new and improved corporate website which will reflect all current business focus. This new website will be launched some time in June.<br /></p>     <p><strong>    Product Development</strong><br />-------------------<br /></p>  <p>    AlphaRx's current focus is on the development of &quot;nanobiotics&quot; for the treatment of severe pneumonias. AlphaRx's high-priority development programs include Vansolin(TM) and Zysolin(TM).<br /></p>  <p>    Vansolin(TM), a specially-formulated Vancomycin nano-particulate formulation, is intended for the treatment of severe pneumonias caused by MRSA (Methicillin Resistant Staphylococcus Aureus) pathogens. Vansolin(TM) is undergoing pivotal animal studies. The Company will make a go/no go decision based on the outcome on these studies which will be available by mid-July.<br /></p>  <p>    Zysolin(TM), a specially-formulated Tobramycin nano-particulate formulation, intended for the treatment of severe pneumonias caused by gram negative pathogens such as Psedomonas Aeruginosa. The Company is developing Zysolin(TM) as a primary therapy for Cystic Fibrosis and an adjunctive therapy for ventilated patients with hospital-acquired, Gram-negative pneumonias. Zysolin(TM) is undergoing pivotal animal studies.<br /></p>   <p><strong>    About AlphaRx Inc.<br /><br /></strong></p>   <p>    AlphaRx is a specialty pharmaceutical company utilizing proprietary site-specific nanoparticulate drug delivery systems to develop novel formulations of drugs that are insoluble or poorly soluble in water or have yet to be administrable to the human body with an acceptable delivery method. The Company's product candidates address various pharmaceutical markets, including inflammation, tuberculosis and pneumonia.<br /></p>   <p><strong>    Forward Looking Statements:<br /><br /></strong></p>   <p>    This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the companies.<br /></p>    <p><strong>For more information, please contact:<br /></strong> <br /><br />AGORACOM Investor Relations Corp.<br /> Web: <a href="http://www.agoracom.com//" target="_blank"><strong>http://www.agoracom.com</strong></a> <br /> E-mail: <a href="mailto:ALRX@Agoracom.com" target="_blank"><strong>ALRX@Agoracom.com</strong></a></p>  <br /><br />]]>
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      <title>[Press Release] NEWS - AlphaRx's Indaflex(TM) Continues its Clinical Development</title>
      <guid>message_827988</guid>
      <pubDate>12 May 2008 08:00:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/827988</link>
      <description>
        <![CDATA[<p><strong>    MARKHAM, ON, May 12 - AlphaRx (OTC BB:ALRX)</strong>, an emerging biopharmaceutical company utilizing proprietary drug delivery technology to develop novel formulations of drugs, is pleased to announce that the clinical development of Indaflex(TM), its topical NSAID (Non-Steroidal Anti-Inflammatory Drug) formulation, will continue as part of Cypress Bioscience, Inc. (&quot;Cypress') (NASDAQ: <a href="http://ca.finance.yahoo.com/q?s=CYPB" target="_blank">CYPB</a>).</p><br /><br /><p>In March 2008, Cypress acquired Proprius Pharmaceuticals, Inc. (&quot;Proprius&quot;). The transaction included an upfront payment of approximately $37.5 million in cash, as well as an additional $37.5 million in potential milestone-related payments associated with the development of Proprius' therapeutic candidates including Indaflex(TM). AlphaRx was notified that the Indaflex licensing agreement has been assigned to Cypress from Proprius as part of that transaction.</p><br /><br /><p>Michael Lee, President of AlphaRx stated, &quot;AlphaRx is excited to see the development of Indaflex continue as part of Cypress' on-going clinical development efforts. We believe Indaflex is in good hands and is consistent with Cypress's therapeutic focus and expertise.&quot;</p><br /><br /><p><strong>About AlphaRx Inc.</strong></p><br /><br /><p>    AlphaRx is a specialty pharmaceutical company utilizing proprietary site-specific nanoparticulate drug delivery systems to develop novel formulations of drugs that are insoluble or poorly soluble in water or have yet to be administrable to the human body with an acceptable delivery method. The Company's product candidates address various pharmaceutical markets, including inflammation, tuberculosis and pneumonia.</p><br /><br /><p><strong>Forward Looking Statements:</strong></p><br /><br /><p>    This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the companies.</p>]]>
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      <title>[Press Release] NEWS - AlphaRx Announces Non-Brokered Private Placement</title>
      <guid>message_772166</guid>
      <pubDate>25 Mar 2008 08:42:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/772166</link>
      <description>
        <![CDATA[  <p><strong>MARKHAM, ON, Mar 25 - AlphaRx (OTC BB:ALRX - News),</strong> is pleased to announce a proposed non-broker<wbr/>ed private placement in conjunctio<wbr/>n with its proposed TSX Venture Exchange listing applicatio<wbr/>n, subject to TSX Venture Exchange approval, of 16,000,000 units at a price of US$0.10 per unit, for gross proceeds of US$1,600,0<wbr/>00. </p>  <p>&nbsp;</p>  <p>Each unit consists of one common share plus one-half common share purchase warrant. Each whole common share purchase warrant will enable the holder to purchase one common share at a price of $0.125 for a period of 24 months from closing. Closing of the private placement is subject to the Company&rs<wbr/>quo;s common shares being listed and posted for trading on the TSX Venture Exchange and the Company becomes a &quot;qual<wbr/>ifying issuer&quo<wbr/>t; as such term is defined in Multi-Late<wbr/>ral Instrument 45-102 of the Canadian Securities Administra<wbr/>tors (&quot;MI 45-102&quo<wbr/>t;) resulting in the securities issued in the private placement qualifying for a four month hold period pursuant to MI 45-102.</p>  <p><strong>&nbsp;</strong></p>  <p>The TSX Venture Exchange has not reviewed this news release and does not accept responsibi<wbr/>lity for the adequacy or accuracy of this news release. The TSXV has neither approved nor disapprove<wbr/>d the contents of this news release.</p>  <p><strong>&nbsp;</strong></p>  <p><strong>About AlphaRx Inc. </strong></p>  <p>AlphaRx is a specialty pharmaceut<wbr/>ical company utilizing proprietar<wbr/>y site-speci<wbr/>fic nanopartic<wbr/>ulate drug delivery systems to develop novel formulatio<wbr/>ns of drugs that are insoluble or poorly soluble in water or have yet to be administra<wbr/>ble to the human body with an acceptable delivery method. The Company&rs<wbr/>quo;s product candidates address various pharmaceut<wbr/>ical markets, including inflammati<wbr/>on, tuberculos<wbr/>is and pneumonia.</p>  <p>&nbsp;</p>  <p><strong>Forward Looking Statements<wbr/>: </strong></p>  <p>This release contains forward-lo<wbr/>oking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertaint<wbr/>ies that may individual<wbr/>ly or mutually impact the matters herein described, including but not limited to product developmen<wbr/>t and acceptance<wbr/>, manufactur<wbr/>ing, competitio<wbr/>n, regulatory and/or other factors, which are outside the control of the companies.</p>  <p>&nbsp;</p>  <p>For more informatio<wbr/>n, please contact:</p>  <p>&nbsp;</p>  <p>AGORACOM Investor Relations Corp.<br /> Web: <a href="http://www.agoracom.com//"><strong>http://www<wbr/>.agoracom.<wbr/>com</strong></a>&nbsp;<br /> E-mail: <a href="mailto:ALRX@Agoracom.com"><strong>ALRX@Agora<wbr/>com.com</strong></a></p>  ]]>
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      <title>[Press Release] NEWS - AlphaRx Initiates Indaflex(TM) China Registration</title>
      <guid>message_711927</guid>
      <pubDate>29 Jan 2008 08:39:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/711927</link>
      <description>
        <![CDATA[<p><strong>    MARKHAM, ON, Jan. 29 - AlphaRx (OTC BB:ALRX)</strong>, an emerging biopharmaceutical company utilizing proprietary drug delivery technology to develop novel formulations of drugs, is pleased to announce that it has commenced preparation of the dossier for the registration of Indaflex(TM) in China.</p><p>&nbsp;</p><p>Indaflex(TM) is a topical NSAID (Non-Steroidal Anti-Inflammatory Drug) formulation in clinical development for the reduction of signs and symptoms associated with osteoarthritis of the knee. The Company expects to file a New Drug Application to the China State Food &amp; Drug Administration (SFDA) in April 2008. The application will be placed under Class 3.1 and as such, the Company is allowed to set Indaflex(TM)'s retail price. This is significant as drug prices are under Government control in China.</p><p>&nbsp;</p><p>The Company will be required to conduct a confirmatory human trial with 240 patients in 2 arms over a 4 weeks treatment period. The Company anticipates completing this trial by Q4 of 2008 in Beijing and Shanghai. Subject to the successful completion of this confirmatory trial, approval from the SFDA of Indaflex(TM) should be received in Q4 of 2009. Upon approval, this will allow for initiation of a comprehensive marketing and distribution campaign.</p><p>&nbsp;</p><p><strong>About AlphaRx Inc.</strong></p><p>&nbsp;</p><p>    AlphaRx is a specialty pharmaceutical company utilizing proprietary site-specific nanoparticulate drug delivery systems to develop novel formulations of drugs that are insoluble or poorly soluble in water or have yet to be administrable to the human body with an acceptable delivery method. The Company's product candidates address various pharmaceutical markets, including inflammation, tuberculosis and pneumonia.</p><p>&nbsp;</p><p><strong>Forward Looking Statements:</strong></p><p>&nbsp;</p><p>    This release contains forward-looking statements within the meaning and pursuant to the Safe Harbor provisions of the Securities Litigation Reform Act of 1995 and involve risks and uncertainties that may individually or mutually impact the matters herein described, including but not limited to product development and acceptance, manufacturing, competition, regulatory and/or other factors, which are outside the control of the companies.</p><p>&nbsp;</p>Copyright @ 2008. AlphaRx Inc.    <p>SOURCE  AlphaRx Inc.</p><p>&nbsp;</p><strong>Contacts</strong><p>AGORACOM Investor Relations Corp. <br />  Web: <a href="http://www.agoracom.com//">http://www.agoracom.com</a> <br />  E-mail: <a href="mailto:ALRX@Agoracom.com">ALRX@Agoracom.com</a> </p>]]>
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      <title>[Press Release] NEWS - AGORACOM Hosts 8 Emerging Companies in Small-Cap Pavilion at 22nd Annual Toronto Financial Forum</title>
      <guid>message_705676</guid>
      <pubDate>22 Jan 2008 13:08:00 GMT</pubDate>
      <link>http://agoracom.com/ir/alpharx/messages/705676</link>
      <description>
        <![CDATA[<strong>TORONTO, ONTARIO -- Jan. 22, 2008 - AGORACOM.com (<a href="http://www.agoracom.com//" target="_blank">http://www.agoracom.com</a>)</strong> is pleased to announce it will be hosting the AGORACOM Small-Cap Pavilion at the 22nd annual Toronto Financial Forum, which takes place this week from January 24th-26th at the Metro Toronto Convention Centre and is expected to attract 10,000 investors. <br /><br /><br />8 Small-Cap Companies Investors Must Know About In 2008<br /><br /> <br />The AGORACOM Small-Cap Pavilion will be located in booths 422-429 and will feature the following 8 emerging small-cap companies:<br /><br /><pre>Admiralty Holding Company      (OTCBB:ADMH)<br />AlphaRx Inc.                   (OTCBB:ALRX)<br />Arianne Resources Inc.         (TSX VENTURE:DAR)<br />CON-SPACE Communications       (TSX VENTURE:CCB)<br />Hi Ho Silver Resources Inc.    (CNQ:HIHO)<br />Ontex Resources Ltd.           (TSX:ONT)<br />RepeatSeat Ltd.                (TSX VENTURE:RPS)<br />Shoreham Resources Ltd.        (TSX VENTURE:SMH)</pre><table border="0"><tbody><tr><td>&nbsp;</td></tr></tbody></table><p> <br />On behalf of all exhibiting companies, AGORACOM would like to invite all shareholders and interested parties to attend the conference.<br /><br /> <br /><strong>About AGORACOM<br /></strong><br /> <br />AGORACOM Investor Relations (<a href="http://www.agoracomir.com/" target="_blank">http://www.AgoracomIR.com</a>) is North America's largest online investor relations firm for small-cap companies. We have partnered with the world's biggest internet companies, including Yahoo, AOL, Google and Blackberry to market our clients to a massive audience of new small-cap investors. We have served over 200 companies since 1997.<br /><br /> <br />AGORACOM Investor Relations has displaced the telephone and e-mail as primary IR communications devices. Our IR HUB delivers two-way investor relations in near real-time that is 24/7/365 accessible to shareholders around the world and goes far beyond text by offering both audio and video communications.<br /><br /> <br />AGORACOM (<a href="http://www.agoracom.com//" target="_blank">http://www.Agoracom.com</a>) is North America's only small-cap community built to serve the needs of serious small-cap and micro-cap investors. No rumors, profanity, stock bashing or hyping. Our traffic ranking is above the top 1% of all websites around the world.<br /><br /> <br />The AGORACOM Investor Relations logo is available at: <a href="http://www.primezone.com/newsroom/prs/?pkgid=2200" target="_blank">www.primezone.com/newsroom/prs/?pkgid=2200</a></p><p>&nbsp;</p><div class="releaseContact"> 	 	<p><strong>For more information, please contact</strong></p> 	  	 		AGORACOM Investor Relations<br />Email: <a href="mailto:AIR@agoracom.com">AIR@agoracom.com</a> 	 	 </div><p>&nbsp;</p>]]>
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