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<?xml-stylesheet type="text/xsl" media="screen" href="/~d/styles/rss2full.xsl"?><?xml-stylesheet type="text/css" media="screen" href="http://feeds.feedburner.com/~d/styles/itemcontent.css"?><rss xmlns:content="http://purl.org/rss/1.0/modules/content/" xmlns:wfw="http://wellformedweb.org/CommentAPI/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:atom="http://www.w3.org/2005/Atom" xmlns:sy="http://purl.org/rss/1.0/modules/syndication/" xmlns:slash="http://purl.org/rss/1.0/modules/slash/" xmlns:feedburner="http://rssnamespace.org/feedburner/ext/1.0" version="2.0"><channel><title>Bitnos</title><link>http://www.bitnos.com</link><description>the best biomedical web applications and search tools! Free!</description><lastBuildDate>Tue, 21 Feb 2012 11:23:06 -0600</lastBuildDate><language>en</language><sy:updatePeriod>hourly</sy:updatePeriod><sy:updateFrequency>1</sy:updateFrequency><generator>http://atunn.com/</generator><ttl>5</ttl><image><url>http://static.atunn.com/logo_bitnos_200x100.png</url><title>Bitnos</title><link>http://www.bitnos.com</link><height>50</height><width>100</width></image><atom10:link xmlns:atom10="http://www.w3.org/2005/Atom" rel="self" type="application/rss+xml" href="http://feeds.feedburner.com/bitnos" /><feedburner:info uri="bitnos" /><atom10:link xmlns:atom10="http://www.w3.org/2005/Atom" rel="hub" href="http://pubsubhubbub.appspot.com/" /><item><title>Provocative Questions</title><link>http://feedproxy.google.com/~r/bitnos/~3/fMuaJyBGZ3A/provocative-questions</link><comments>http://www.bitnos.com/info/provocative-questions/#site_comments</comments><pubDate>Tue, 21 Feb 2012 11:23:06 +0600</pubDate><dc:creator>Bitnos</dc:creator><category><![CDATA[Cancer research]]></category><category><![CDATA[Biomedical funding and jobs]]></category><guid isPermaLink="false">http://www.bitnos.com/?site_id=4206</guid><description><![CDATA[The Provocative Questions initiative from NCI asks investigators to propose important but non-obvious questions in cancer research that need attention...]]></description><content:encoded><![CDATA[The Provocative Questions initiative from NCI asks investigators to propose important but non-obvious questions in cancer research that need attention but would usually find it difficult to get.NCI has issued a request for applications and provisionally set aside US$15 million from the budget for fiscal year 2012 to support the best ideas for answering any of the questions chosen from a list of 24.<img src="http://feeds.feedburner.com/~r/bitnos/~4/fMuaJyBGZ3A" height="1" width="1"/>]]></content:encoded><slash:comments>0</slash:comments><feedburner:origLink>http://www.bitnos.com/info/provocative-questions</feedburner:origLink></item><item><title>ISA metadata tracking tools</title><link>http://feedproxy.google.com/~r/bitnos/~3/TTge8Cvzkis/isa-metadata-tracking-tools</link><comments>http://www.bitnos.com/info/isa-metadata-tracking-tools/#site_comments</comments><pubDate>Mon, 13 Feb 2012 06:00:00 +0600</pubDate><dc:creator>Bitnos</dc:creator><category><![CDATA[Other software]]></category><guid isPermaLink="false">http://www.bitnos.com/?site_id=4205</guid><description><![CDATA[The open source ISA metadata tracking tools facilitates standards compliant collection, curation, local management and reuse of datasets in an increas...]]></description><content:encoded><![CDATA[The open source ISA metadata tracking tools facilitates standards compliant collection, curation, local management and reuse of datasets in an increasingly diverse set of life science domains. Built around the &lsquo;Investigation&rsquo; (the project context), &lsquo;Study&rsquo; (a unit of research) and &lsquo;Assay&rsquo; (analytical measurement) metadata categories, the tools are designed to manage studies employing one or a combination of technologies.<img src="http://feeds.feedburner.com/~r/bitnos/~4/TTge8Cvzkis" height="1" width="1"/>]]></content:encoded><slash:comments>0</slash:comments><feedburner:origLink>http://www.bitnos.com/info/isa-metadata-tracking-tools</feedburner:origLink></item><item><title>ISA Commons</title><link>http://feedproxy.google.com/~r/bitnos/~3/P1mXBdk-q04/isa-commons</link><comments>http://www.bitnos.com/info/isa-commons/#site_comments</comments><pubDate>Mon, 13 Feb 2012 05:57:29 +0600</pubDate><dc:creator>Bitnos</dc:creator><category><![CDATA[Biomedical communities]]></category><guid isPermaLink="false">http://www.bitnos.com/?site_id=4204</guid><description><![CDATA[The ISA Commons is a growing community that uses the ISA metadata tracking framework to facilitate standards-compliant collection, curation, managemen...]]></description><content:encoded><![CDATA[The ISA Commons is a growing community that uses the ISA metadata tracking framework to facilitate standards-compliant collection, curation, management and reuse of datasets in an increasingly diverse set of life science domains<img src="http://feeds.feedburner.com/~r/bitnos/~4/P1mXBdk-q04" height="1" width="1"/>]]></content:encoded><slash:comments>0</slash:comments><feedburner:origLink>http://www.bitnos.com/info/isa-commons</feedburner:origLink></item><item><title>SCDE Stem Cell Discovery Engine</title><link>http://feedproxy.google.com/~r/bitnos/~3/znTq2d0_eME/scde-stem-cell-discovery-engine</link><comments>http://www.bitnos.com/info/scde-stem-cell-discovery-engine/#site_comments</comments><pubDate>Mon, 13 Feb 2012 05:37:39 +0600</pubDate><dc:creator>Bitnos</dc:creator><category><![CDATA[Cancer research]]></category><guid isPermaLink="false">http://www.bitnos.com/?site_id=4203</guid><description><![CDATA[The Stem Cell Discovery Engine Driven was developed by the need to understand cancer stem cells molecular profiles generated at the Harvard Stem Cell ...]]></description><enclosure url="http://www.bitnos.com/database-images/4203.jpg" length="2227" type="image/jpeg" /><content:encoded><![CDATA[The Stem Cell Discovery Engine Driven was developed by the need to understand cancer stem cells molecular profiles generated at the Harvard Stem Cell Institute (HSCI). SCDE is a modular online system designed to handle data submission, curation, analysis, integration and dissemination of stem cell-related experiments.<img src="http://feeds.feedburner.com/~r/bitnos/~4/znTq2d0_eME" height="1" width="1"/>]]></content:encoded><slash:comments>0</slash:comments><feedburner:origLink>http://www.bitnos.com/info/scde-stem-cell-discovery-engine</feedburner:origLink></item><item><title>Comet Assay Interest Group</title><link>http://feedproxy.google.com/~r/bitnos/~3/BppwwaQKJx8/comet-assay</link><comments>http://www.bitnos.com/info/comet-assay/#site_comments</comments><pubDate>Mon, 13 Feb 2012 05:20:11 +0600</pubDate><dc:creator>Bitnos</dc:creator><category><![CDATA[Biomedical communities]]></category><guid isPermaLink="false">http://www.bitnos.com/?site_id=3624</guid><description><![CDATA[The Comet assay interest group is a free forum for exchange of information on Comet assay worldwide.  By joining this group you will have free access ...]]></description><content:encoded><![CDATA[The Comet assay interest group is a free forum for exchange of information on Comet assay worldwide.  By joining this group you will have free access to the latest developments in this field as well as access to archived discussions (at NIH Listserv)  from the last several years. You can also send your message/queries to the entire group.<img src="http://feeds.feedburner.com/~r/bitnos/~4/BppwwaQKJx8" height="1" width="1"/>]]></content:encoded><slash:comments>0</slash:comments><feedburner:origLink>http://www.bitnos.com/info/comet-assay</feedburner:origLink></item><item><title>HaploReg</title><link>http://feedproxy.google.com/~r/bitnos/~3/fhjM7O8dLrE/haploreg</link><comments>http://www.bitnos.com/info/haploreg/#site_comments</comments><pubDate>Sun, 12 Feb 2012 12:13:34 +0600</pubDate><dc:creator>Bitnos</dc:creator><category><![CDATA[Genetic variations]]></category><guid isPermaLink="false">http://www.bitnos.com/?site_id=4202</guid><description><![CDATA[HaploReg is a tool for exploring annotations of the noncoding genome at variants on haplotype blocks, such as candidate regulatory SNPs at disease-ass...]]></description><enclosure url="http://www.bitnos.com/database-images/4202.jpg" length="11859" type="image/jpeg" /><content:encoded><![CDATA[HaploReg is a tool for exploring annotations of the noncoding genome at variants on haplotype blocks, such as candidate regulatory SNPs at disease-associated loci. It brings together data from chromatin-mapping and comparative-genomics studies. Researchers can enter common variants and see whether they fall in a highly conserved region, disrupt a regulatory motif or are associated with a regulatory element in a particular cell type. It provides the same information for common variants that tend to be inherited along with the ones entered.<img src="http://feeds.feedburner.com/~r/bitnos/~4/fhjM7O8dLrE" height="1" width="1"/>]]></content:encoded><slash:comments>0</slash:comments><feedburner:origLink>http://www.bitnos.com/info/haploreg</feedburner:origLink></item><item><title>RegulomeDB</title><link>http://feedproxy.google.com/~r/bitnos/~3/CbZ6wPNKP6k/regulomedb</link><comments>http://www.bitnos.com/info/regulomedb/#site_comments</comments><pubDate>Sun, 12 Feb 2012 12:07:54 +0600</pubDate><dc:creator>Bitnos</dc:creator><category><![CDATA[Genetic variations]]></category><guid isPermaLink="false">http://www.bitnos.com/?site_id=4201</guid><description><![CDATA[RegulomeDB identifies binding sites and other elements in non-coding DNA....]]></description><content:encoded><![CDATA[RegulomeDB identifies binding sites and other elements in non-coding DNA.<img src="http://feeds.feedburner.com/~r/bitnos/~4/CbZ6wPNKP6k" height="1" width="1"/>]]></content:encoded><slash:comments>0</slash:comments><feedburner:origLink>http://www.bitnos.com/info/regulomedb</feedburner:origLink></item><item><title>ANNOVAr</title><link>http://feedproxy.google.com/~r/bitnos/~3/oaR4b6S_Opc/annovar</link><comments>http://www.bitnos.com/info/annovar/#site_comments</comments><pubDate>Sun, 12 Feb 2012 11:46:27 +0600</pubDate><dc:creator>Bitnos</dc:creator><category><![CDATA[Genomics software]]></category><guid isPermaLink="false">http://www.bitnos.com/?site_id=4200</guid><description><![CDATA[ANNOVAR: Functional annotation of genetic variants from high-throughput sequencing data. ANNOVAR is an efficient software tool to utilize update-to-da...]]></description><content:encoded><![CDATA[ANNOVAR: Functional annotation of genetic variants from high-throughput sequencing data. ANNOVAR is an efficient software tool to utilize update-to-date information to functionally annotate genetic variants detected from diverse genomes (including human genome hg18, hg19, as well as mouse, worm, fly, yeast and many others).ANNOVAR is written in Perl and can be run as a standalone application on diverse hardware systems where standard Perl modules are installed.<img src="http://feeds.feedburner.com/~r/bitnos/~4/oaR4b6S_Opc" height="1" width="1"/>]]></content:encoded><slash:comments>0</slash:comments><feedburner:origLink>http://www.bitnos.com/info/annovar</feedburner:origLink></item><item><title>VAAST</title><link>http://feedproxy.google.com/~r/bitnos/~3/ONVIHsCkwYw/vaast</link><comments>http://www.bitnos.com/info/vaast/#site_comments</comments><pubDate>Sun, 12 Feb 2012 11:39:11 +0600</pubDate><dc:creator>Bitnos</dc:creator><category><![CDATA[Genomics software]]></category><guid isPermaLink="false">http://www.bitnos.com/?site_id=4199</guid><description><![CDATA[VAAST (the Variant Annotation, Analysis and Search Tool) is a probabilistic search tool for identifying damaged genes and their disease-causing varian...]]></description><content:encoded><![CDATA[VAAST (the Variant Annotation, Analysis and Search Tool) is a probabilistic search tool for identifying damaged genes and their disease-causing variants in personal genome sequences. VAAST can score both coding and non-coding variants, evaluating the cumulative impact of both types of variants simultaneously. VAAST can identify rare variants causing rare genetic diseases, and it can also use both rare and common variants to identify genes responsible for common diseases.<img src="http://feeds.feedburner.com/~r/bitnos/~4/ONVIHsCkwYw" height="1" width="1"/>]]></content:encoded><slash:comments>0</slash:comments><feedburner:origLink>http://www.bitnos.com/info/vaast</feedburner:origLink></item><item><title>SIFT</title><link>http://feedproxy.google.com/~r/bitnos/~3/-L_oNNnHXNc/sift-2</link><comments>http://www.bitnos.com/info/sift-2/#site_comments</comments><pubDate>Sun, 12 Feb 2012 11:36:27 +0600</pubDate><dc:creator>Bitnos</dc:creator><category><![CDATA[Genomics software]]></category><guid isPermaLink="false">http://www.bitnos.com/?site_id=4193</guid><description><![CDATA[SIFT predicts whether an amino acid substitution affects protein function....]]></description><content:encoded><![CDATA[SIFT predicts whether an amino acid substitution affects protein function.<img src="http://feeds.feedburner.com/~r/bitnos/~4/-L_oNNnHXNc" height="1" width="1"/>]]></content:encoded><slash:comments>0</slash:comments><feedburner:origLink>http://www.bitnos.com/info/sift-2</feedburner:origLink></item><item><title>PHAST</title><link>http://feedproxy.google.com/~r/bitnos/~3/a2z2tvy5tIQ/phast</link><comments>http://www.bitnos.com/info/phast/#site_comments</comments><pubDate>Sun, 12 Feb 2012 11:36:03 +0600</pubDate><dc:creator>Bitnos</dc:creator><category><![CDATA[Genomics software]]></category><guid isPermaLink="false">http://www.bitnos.com/?site_id=4197</guid><description><![CDATA[PHAST is a freely available software package for comparative and evolutionary genomics. It consists of about half a dozen major programs, plus more th...]]></description><content:encoded><![CDATA[PHAST is a freely available software package for comparative and evolutionary genomics. It consists of about half a dozen major programs, plus more than a dozen utilities for manipulating sequence alignments, phylogenetic trees, and genomic annotations (see left panel).Like algorithms that assess protein-coding genes, they evaluate variants on the basis of how often the sequence changes between species<img src="http://feeds.feedburner.com/~r/bitnos/~4/a2z2tvy5tIQ" height="1" width="1"/>]]></content:encoded><slash:comments>0</slash:comments><feedburner:origLink>http://www.bitnos.com/info/phast</feedburner:origLink></item><item><title>GERP</title><link>http://feedproxy.google.com/~r/bitnos/~3/67JVDw6ukdg/gerp</link><comments>http://www.bitnos.com/info/gerp/#site_comments</comments><pubDate>Sun, 12 Feb 2012 11:35:31 +0600</pubDate><dc:creator>Bitnos</dc:creator><category><![CDATA[Genomics software]]></category><guid isPermaLink="false">http://www.bitnos.com/?site_id=4198</guid><description><![CDATA[Genomic Evolutionary Rate Profiling (GERP) identifies constrained elements in multiple alignments by quantifying substitution deficits. These deficits...]]></description><enclosure url="http://www.bitnos.com/database-images/4198.jpg" length="3983" type="image/jpeg" /><content:encoded><![CDATA[Genomic Evolutionary Rate Profiling (GERP) identifies constrained elements in multiple alignments by quantifying substitution deficits. These deficits represent substitutions that would have occurred if the element were neutral DNA, but did not occur because the element has been under functional constraint. We refer to these deficits as &quot;Rejected Substitutions&quot;.<img src="http://feeds.feedburner.com/~r/bitnos/~4/67JVDw6ukdg" height="1" width="1"/>]]></content:encoded><slash:comments>0</slash:comments><feedburner:origLink>http://www.bitnos.com/info/gerp</feedburner:origLink></item><item><title>SIFT</title><link>http://feedproxy.google.com/~r/bitnos/~3/Cw0DHIyHojM/sift</link><comments>http://www.bitnos.com/info/sift/#site_comments</comments><pubDate>Sun, 12 Feb 2012 11:34:14 +0600</pubDate><dc:creator>Bitnos</dc:creator><category><![CDATA[Genetic variations]]></category><guid isPermaLink="false">http://www.bitnos.com/?site_id=4194</guid><description><![CDATA[SIFT (Sorting Intolerant From Tolerant) predicts whether an amino acid substitution affects protein function based on sequence homology and the physic...]]></description><content:encoded><![CDATA[SIFT (Sorting Intolerant From Tolerant) predicts whether an amino acid substitution affects protein function based on sequence homology and the physical properties of amino acids. SIFT can be applied to naturally occurring nonsynonymous polymorphisms and laboratory-induced missense mutations.<img src="http://feeds.feedburner.com/~r/bitnos/~4/Cw0DHIyHojM" height="1" width="1"/>]]></content:encoded><slash:comments>0</slash:comments><feedburner:origLink>http://www.bitnos.com/info/sift</feedburner:origLink></item><item><title>Pyromaker</title><link>http://feedproxy.google.com/~r/bitnos/~3/PzKhbnR_WjM/pyromaker</link><comments>http://www.bitnos.com/info/pyromaker/#site_comments</comments><pubDate>Fri, 10 Feb 2012 06:08:40 +0600</pubDate><dc:creator>Bitnos</dc:creator><category><![CDATA[DNA sequencing]]></category><category><![CDATA[Cancer miscellaneous]]></category><guid isPermaLink="false">http://www.bitnos.com/?site_id=4195</guid><description><![CDATA[Pyromaker is a web-based application that produces simulated pyrograms based on user input including the percentage of tumor and normal cells, the wil...]]></description><content:encoded><![CDATA[Pyromaker is a web-based application that produces simulated pyrograms based on user input including the percentage of tumor and normal cells, the wild-type sequence, the dispensation order, and any number of mutant sequences. Pyromaker calculates the relative mutant and wild-type allele percentages and then uses these to generate the expected signal at each point in the dispensation sequence. The final result is a virtual trace of the expected pyrogram<img src="http://feeds.feedburner.com/~r/bitnos/~4/PzKhbnR_WjM" height="1" width="1"/>]]></content:encoded><slash:comments>0</slash:comments><feedburner:origLink>http://www.bitnos.com/info/pyromaker</feedburner:origLink></item><item><title>Drosophila melanogaster Genetic Reference Panel (DGRP)</title><link>http://feedproxy.google.com/~r/bitnos/~3/gL93bygYjdw/drosophila-melanogaster-genetic-reference-panel-dgrp</link><comments>http://www.bitnos.com/info/drosophila-melanogaster-genetic-reference-panel-dgrp/#site_comments</comments><pubDate>Thu, 09 Feb 2012 04:38:02 +0600</pubDate><dc:creator>Bitnos</dc:creator><category><![CDATA[Model organisms]]></category><guid isPermaLink="false">http://www.bitnos.com/?site_id=4196</guid><description><![CDATA[The DGRP is a community resource for association mapping of quantitative trait loci. It consists of fully sequenced inbred lines derived from a natura...]]></description><enclosure url="http://www.bitnos.com/database-images/4196.jpg" length="3753" type="image/jpeg" /><content:encoded><![CDATA[The DGRP is a community resource for association mapping of quantitative trait loci. It consists of fully sequenced inbred lines derived from a natural population. The DGRP facilitates genotype&ndash;phenotype mapping using the power of Drosophila genetics<img src="http://feeds.feedburner.com/~r/bitnos/~4/gL93bygYjdw" height="1" width="1"/>]]></content:encoded><slash:comments>0</slash:comments><feedburner:origLink>http://www.bitnos.com/info/drosophila-melanogaster-genetic-reference-panel-dgrp</feedburner:origLink></item></channel></rss>

