ALZHEIMER'S NEWS

Без сваёй царквы немагчыма збудаваць сваю дзяржаву - Беларуская Праўда

2018-09-09T09:06:00.001-07:00

Без сваёй царквы немагчыма збудаваць сваю дзяржаву - Беларуская Праўда

2016-06-09T03:50:00.001-07:00

Blood test for Alzheimer’s shows 100 percent accuracy in early trials: "Led by Nagele, the Rowan University team took blood samples from 236 patients, 50 of which had been diagnosed with Alzheimer's due to the low-level presence of amyloid-beta 42 peptide in their cerebrospinal fluid. These are the peptides that gather in clusters and go on to form amyloid plaques in the brain, which are considered the culprits behind the debilitating disease.

"

'via Blog this'

2016-05-30T04:35:00.001-07:00

What Are Free Radicals?:

'via Blog this'

2016-05-29T04:35:00.001-07:00

Harvard researchers unveil new Alzheimer's theory | WFAA.com:

'via Blog this'

French study shows delaying retirement reduces Alzheimer's risk | khou.com Houston

2013-07-19T11:52:00.001-07:00

French study shows delaying retirement reduces Alzheimer's risk | khou.com Houston:

'via Blog this'

Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals

2013-07-03T12:22:00.001-07:00

Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals

Protein-Repairing Methionine Sulfoxide Reductases in Photosynthetic Organisms: Gene Organization, Reduction Mechanisms, and Physiological Roles

2013-07-03T12:12:00.001-07:00

Protein-Repairing Methionine Sulfoxide Reductases in Photosynthetic Organisms: Gene Organization, Reduction Mechanisms, and Physiological Roles

digitalcommons.unl.edu/cgi/viewcontent.cgi?article=1003&context=biochemdiss

2013-07-03T12:03:00.001-07:00

digitalcommons.unl.edu/cgi/viewcontent.cgi?article=1003&context=biochemdiss

BioVendor R&D - Molecules \ Methionine sulfoxide reductase B

2013-07-03T12:01:00.001-07:00

BioVendor R&D - Molecules \ Methionine sulfoxide reductase B

Is This Drug the Key to an Alzheimer's Cure? - Money Morning

2013-01-28T10:33:00.001-08:00

Is This Drug the Key to an Alzheimer's Cure? - Money Morning:

'via Blog this'

Lilly Last Hope for Alzheimer’s as Pfizer, J&J Bow Out - Bloomberg

2012-08-08T08:35:00.001-07:00

Lilly Last Hope for Alzheimer’s as Pfizer, J&J Bow Out - Bloomberg:

'via Blog this'

2012-07-24T14:44:00.001-07:00

Wonder pill could treat Alzheimer's, Parkinson's AND multiple sclerosis | Mail Online:

'via Blog this'

The Astrocytes Cells Retaliate in Alzheimer's

2012-05-26T04:07:00.001-07:00

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(suicide package instead)

Amyloid is excreted by all neurons, but rates increase with aging and dramatically accelerate in Alzheimer's. Astrocytes, which deliver blood, oxygen and nutrients to neurons in addition to hauling off some of their garbage, get activated and inflamed by excessive amyloid.

Now researchers have shown another way astrocytes respond is by packaging the lipid ceramide with the protein PAR-4, which independently can do damage but together are a more "deadly duo," said Dr. Erhard Bieberich, biochemist at the Medical College of Georgia at Georgia Health Sciences University.

"If the neuron makes something toxic and dumps it at your door, what would you do?" said Bieberich, corresponding author of the study published in the Journal of Biological Chemistry. "You would probably do something to defend yourself." Continue to read: sciencedaily.com

Read more here: http://www.bnd.com/2012/02/07/2047945/obama-to-seek-more-alzheimers.html#storylink=cpy

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Optimal vitamin-D linked to lower heart disease death

People with the metabolic syndrome may be at a lower risk of dying from cardiovascular disease if they have optimal vitamin D levels, suggests new data from Europe. Read more: nutraingredients.com

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Game Helps Alzheimer's Patients Form Memories

2012-05-25T06:46:00.001-07:00

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(daily activities like cooking a meal)

The brain is basically a series of networked nerve cells transferring information along billions of connections. We aren't certain how it works, but we do know that people who suffer from dementia as a result of Alzheimer's disease have trouble forming new connections and therefore retaining information. A student from Staffordshire University in the UK has been working on a videogame calledLife in Memory Lane which assists the player in storing memories by assembling bits of biographical information. The new memory is then shown to the player through a short piece of video set to music.

"This is something I'm really passionate about," said Zohabe Aziz, the 23-year-old designer of the game. "A lot of games and activities do not relate to people with dementia. I've tried to relate mine to the person and their experiences to keep their memories intact while keeping the design simple and user-friendly so they can navigate their way through the game using quite large buttons.". Continue to read: escapistmagazine.com

Read more here: http://www.bnd.com/2012/02/07/2047945/obama-to-seek-more-alzheimers.html#storylink=cpy

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Folic acid fortification may reduce childhood cancer risk

Fortification of foods with folic acid could help to reduce the incidence of some of the most common types of kidney and brain cancers in children, suggests new research. Read more: nutraingredients.com

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The National Institutes of Health outlined three brain-protective steps

2012-05-24T07:21:00.001-07:00

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(Staying sharp)

• Exercise your brain: Intellectual and social stimulation help build "cognitive reserve."

• Get physical: Clogged arteries slow blood flow to the brain, and people who are less active in middle age are at increased risk of Alzheimer's when they're older.

• Eat right: The same foods that are heart-healthy are brain-healthy, such as the omega-3 fatty acids found in fish. Continue to read: postbulletin.com

Read more here: http://www.bnd.com/2012/02/07/2047945/obama-to-seek-more-alzheimers.html#storylink=cpy

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Abbott Nutrition Cognition research

The first research projects to emerge from a tie-up between Abbott and the University of Illinois Urbana-Champaign (UIUC) will advance our understanding of the relationship between diet and cognition - and help Abbott create the next generation of brain foods targeting consumers at every life stage - claims the healthcare. Read more: nutraingredients-usa.com

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The quick test is designed to identify memory lapses

2012-05-23T07:16:00.001-07:00

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(delay dementia and have independent life)

A ten-minute memory test that picks up Alzheimer’s disease and other forms of dementia in their earliest stages is available for use in GPs’ surgeries from today.

The test distinguishes between normal forgetfulness and the more dangerous memory lapses that can signal dementia.

Early diagnosis would allow patients to receive drug treatment when it would help them the most, letting them work and live independently for longer. Questions on how well the patient manages in day-to-day life are included, as well as some designed to pick up those who may be depressed, rather than on the road to dementia.

A patient’s score, which takes into account their age, sex and education, determines whether they are referred on to a specialist memory clinic for further diagnosis and treatment. Continue to read: dailymail.co.uk

Read more here: http://www.bnd.com/2012/02/07/2047945/obama-to-seek-more-alzheimers.html#storylink=cpy

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Cheese intake during pregnancy may reduce childhood tooth decay

A high intake of cheese during pregnancy may reduce the risk of dental decay during childhood, a study has revealed. Read more: nutraingredients.com

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Genentech gets major Alzheimer's trial

2012-05-22T07:03:00.000-07:00

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( to remove beta amyloids from patients )

Genentech has been awarded the right to run a trial on an experimental drug that could cure Alzheimer's, a disease that currently has no known cure. The pioneering drug trial approved this week for the South San Francisco biotech firm comes on the heels of an Obama Administration announcement regarding a new initiative that aims to eventually eliminate Alzheimer's disease.

Currently one of the leading causes of death, Alzheimer's ravages the brains of its victims, destroying their memories in the process. It is a type of dementia that causes problems with memory, thinking and behavior. Scientists hope that by the year 2025 they will be able to uncover a viable treatment, if not an outright cure. Such a breakthrough would be a potentially award-winning achievement in the careers of Genentech's researchers.

Genentech is at the forefront of the quest to solve the Alzheimer's dilemma. Its scientists will administer their drug on a selected group of patients in Colombia chosen because they carry a specific gene that makes them more likely to develop Alzheimer's at an early age. This trial will mark the first time that a preventative test will be run on people prior to the onset of symptoms. Continue to read: examiner.com

Read more here: http://www.bnd.com/2012/02/07/2047945/obama-to-seek-more-alzheimers.html#storylink=cpy

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Breast milk compound important in feeding good bacteria

Human milk oligosaccharides produce short-chain fatty acids that help feed beneficial bacteria in the infant gut, according to new research in pigs. Read more: nutraingredients.com

Беларусь ТВ

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Vascular problems are at the heart of Alzheimer’s disease

2012-05-21T07:13:00.002-07:00

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(five times as much cyclophilin A)

The well-known Alzheimer’s disease genetic risk factor ApoE4 triggers a cascade of signaling that ultimately results in leaky blood vessels in the brain, allowing toxic substances to pour into brain tissue in large amounts, scientists report.

The results come from a team of scientists investigating why a gene called ApoE4 makes people more prone to developing Alzheimer’s. People who carry two copies of the gene have roughly eight to 10 times the risk of getting Alzheimer’s disease than people who do not.

A team of scientists found that ApoE4 works through cyclophilin A, a well-known bad actor in the cardiovascular system, causing inflammation in atherosclerosis and other conditions. The team found that cyclophilin A opens the gates to the brain assault seen in Alzheimer’s.. Continue to read: ahealthblog.com

Read more here: http://www.bnd.com/2012/02/07/2047945/obama-to-seek-more-alzheimers.html#storylink=cpy

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Breakfast eggs offer better protein satiety benefits

Breakfast eggs that deliver high quality protein may better boost satiety, research has found. Read more: nutraingredients.com

Беларусь ТВ

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A sense of meaning in life can mitigate symptoms of the degenerative disease

2012-05-20T05:53:00.000-07:00

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(making brain quicker, brighter, or a faster processor)

From a neurobiological perspective, two of the biggest markers of Alzheimer’s disease are an accumulation of plaque and what neurologists call “tangles” in the pathways of the brain. The researchers did not find any physical difference in the level of plaque or tangles in the brains of people who rated highly on the purpose of life scale, versus those who did not. (A strong sense of purpose in life does not, in other words, prevent the accumulation of potentially harmful material in the brain.)

But when the Rush researchers looked at participants whose brains, upon autopsy, had identical levels of plaque and tangles, and then correlated that with how those people had rated in terms of both cognitive functioning and a strong purpose of life — controlling for other factors ranging from overall physical health, exercise, education, and IQ to personality traits and inclinations for depression and other psychological issues — the people who rated highly on the purpose of life scale had a 30 percent lower rate of cognitive decline, over the whole study period, than those with low scores on the purpose of life scale.

What that means, according to the researchers, is that a strong sense of purpose in life evidently strengthens or provides a higher level of what’s known as “neural reserve” in the brain. “Reserve” is the quality that allows many physiological systems in the human body to sustain what the Rush researchers call “extensive organ damage” before showing clinical deficits. Neurobiologists specializing in aging have already determined that this concept also applies to the human brain, because most of us — regardless of whether we develop clinical symptoms of “Alzheimer’s disease” or not — will accumulate harmful amounts of plaque and tangles in our brains as we age. Autopsies show that. What the Rush researchers’ results indicate is that having a strong sense of purpose in life, especially beyond the age of 80, can give a person’s brain the ability to sustain that damage and continue to function at a much higher level. Continue to read: wordpress.com

Read more here: http://www.bnd.com/2012/02/07/2047945/obama-to-seek-more-alzheimers.html#storylink=cpy

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New category of yogurt

Danone has launched a “new category” of yogurt to Spanish consumers – offering the experience of eating ice cream with the nutritional benefits of yogurt. Read more: dairyreporter.com

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Hunt Ways to Stall Alzheimer's

2012-05-19T05:10:00.001-07:00

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(Once the train leaves the station of degeneration, it might be too late to stop it)

The research world is set to see a fundamental shift in how scientists hunt ways to ward off the devastation of Alzheimer's disease. One of the most intriguing new methods: testing possible therapies in people who don't yet show many symptoms, before too much of the brain is destroyed.

An international study announced Tuesday, for instance, will track whether an experimental drug can stall the disease in people who appear healthy but are genetically destined to get a type of Alzheimer's that runs in the family. If so, it would be exciting evidence that maybe regular Alzheimer's is preventable too.

A second study will test whether a nasal spray that sends insulin to the brain helps people with very early memory problems, based on separate research linking diabetes to an increased risk of Alzheimer's.

The new focus emerges as the Obama administration adopts the first national strategy to fight the worsening Alzheimer's epidemic - a plan that sets the clock ticking toward finally having effective treatments by 2025. Continue to read: theskanner.com

Read more here: http://www.bnd.com/2012/02/07/2047945/obama-to-seek-more-alzheimers.html#storylink=cpy

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Black tea shows heart health benefits

Three cups of black tea per day may improve heart health measures, such as cholesterol and triglyceride levels, says a study from Mauritius, Scotland, and the USA. Read more: nutraingredients-usa.com

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Avoiding Alzheimer’s Disease

2012-05-18T07:19:00.001-07:00

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(takespecial care)

It is sometimes called the cruelest of diseases, because of the sheer number of people it affects. More than five million people living in the United States have Alzheimer's Disease, according to the National Institute on Aging. By the year 2025, that number could triple. Still uncounted are the vast numbers whose lives are consumed with caring for family members with the disease.

But now there's new hope: The Obama administration has announced the National Alzheimer’s Plan, an unprecedented initiative which seeks to find a cure--or at least a proven treatment--by the year 2025.

Meanwhile, there are measures you can take on your own that may help you avoid the disease. The steps listed below have all shown promise in clinical trials. Be sure to consult a physician before undertaking any major changes in your diet or lifestyle. Continue to read: examiner.com

Read more here: http://www.bnd.com/2012/02/07/2047945/obama-to-seek-more-alzheimers.html#storylink=cpy

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Reduce cataract risk

Lutein and zeaxanthin may protect the lens of the eye from oxidative stress and reduce the risk of cataracts, says a new study. Read more: nutraingredients.com

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Treating Alzheimer’s Disease - Early Intervention

2012-05-17T07:15:00.000-07:00

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(randomized, double-blind, placebo-controlled)

Researchers at the Comprehensive Alzheimer’s Program at the University of California, San Diego School of Medicine have announced two new clinical trials for patients with either mild to moderate Alzheimer’s disease (AD) and one trial for Mild Cognitive Impairment.

“Two of these studies represent an exciting new approach to treating Alzheimer’s, focusing on improving memory in patients with early symptoms of impaired memory and possibly slowing down the disease progression long before symptoms appear,” said Michael Rafii, MD, PhD, assistant professor of neurosciences and director of the Memory Disorders Clinic at UC San Diego . Continue to read: ucsdnews.ucsd.edu

Read more here: http://www.bnd.com/2012/02/07/2047945/obama-to-seek-more-alzheimers.html#storylink=cpy

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Cellular benefits of omega-3

The processes behind the widely reported health benefits of omega-3 fatty acids has been revealed for the first time by a team of researchers in the USA. Read more: nutraingredients.com

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Decrease your risk for Alzheimer’s

2012-05-16T07:21:00.001-07:00

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(lack of exercise, smoking, high blood pressure, high cholesterol)

For years, we’ve been told there’s little we can do to prevent Alzheimer’s disease. All we can do is hope for the best and wait for a cure. But new research shows there are some things we can do to protect our brains as we age. In fact, a recent study found that walking is one of the best ways to slow down the progression of Alzheimer’s disease if you already have it — or cut your risk, if you don’t.

Walking just five miles a week can reduce the chances of the disease getting worse in people who already have it, the study said. And to reduce the chance of developing it, healthy people should walk at least six miles a week. As it turns out, walking strengthens the brain’s memory circuits and can help reduce memory loss over time.

Other ways to keep cognitive abilities sharp include reading the newspaper every day, learning a second language, taking up a new hobby or learning a new skill. The greater the novelty and challenge of the activity, the larger the deposit in the brain’s reserves. In other words, people who continue learning new things are less likely to develop Alzheimer’s disease and dementia. So if you have never learned a second language, try it. If you have never learned to read music, or paint or play an instrument, try it. Continue to read: southtownstar.suntimes.com

Read more here: http://www.bnd.com/2012/02/07/2047945/obama-to-seek-more-alzheimers.html#storylink=cpy

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Vitamin-B may offer blood pressure benefits to 1 in 10 people

Increased intake of vitamin B2 (riboflavin) could significantly lower blood pressure in around 10 percent of people, according to new research that links a common genetic factor with the vitamin. Read more: nutraingredients.com

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Red wine component in Alzheimer's battle

2012-05-15T08:57:00.001-07:00

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( found in the tomatoes, dark chocolate and nuts )

Studies on non-humans have shown it activitates a gene that protects the body and brain from aging. The greatest risk factor for Alzheimer's is aging. Researchers will do baseline tests to identify biological markers of the disease and then other tests to determine if it is progressing.

"Alzheimer's is not an overnight process," says Laurie Ryan, program director for the National Institute on Aging's Alzheimer's Disease Clinical Trials program. "Symptoms don't appear until years after the disease has started. So the thought is if we can delay it from starting or progressing, we can add quality years to the end of life." For Alzheimer's patients, compared with people with normal cognitive skills, neurons die off at a faster rate and shed a protein called tau. Tau forms into tangles, causing havoc with the synapses required for cognitive functions. The researchers will test to see if neuron loss decreases in people who receive resveratrol. Continue to read: 9news.com

Read more here: http://www.bnd.com/2012/02/07/2047945/obama-to-seek-more-alzheimers.html#storylink=cpy

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Vitamin-E may protect against oxidative stress

Daily supplements of vitamin E may protect cells from the detrimental effects of oxidative stress in healthy middle-aged to elderly people. Read more: nutraingredients-usa.com

Беларусь ТВ

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Intervention in Alzheimers’ disease

2012-05-14T12:42:00.002-07:00

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(Deep Brain Stimulation)

A recent study published in theArchives of Neurology reports that DBS appears to increase neuronal activity and connectivity in a handful of patients with suspected mild Alzheimer’s disease. The study, titled “Increased Cerebral Metabolism After 1 Year of Deep Brain Stimulation in Alzheimer Disease,” states: Increased connectivity after 1 year of DBS is observed, which is in contrast to the decreased connectivity observed over the course of [Alzheimer's disease (AD) ]. The persistent cortical metabolic increases after 1 year of DBS were associated with better clinical outcomes in this patient sample and are greater in magnitude and more extensive in the effects on cortical circuitry compared with the effects reported for pharmacotherapy over 1 year in AD. Continue to read: medgadget.com

Read more here: http://www.bnd.com/2012/02/07/2047945/obama-to-seek-more-alzheimers.html#storylink=cpy

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Prawn peptides are ACE for blood pressure

Peptide extracts from the Arctic prawn Pandalus Borealis have demonstrated blood pressure benefits via the, “most potent Angiotensin Converting Enzyme (ACE) inhibiting peptide concentrate that is reported in scientific literature.”. Read more: nutraingredients.com

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