pharmaceutical care (薬学的ケア)

RENEW MOISTURIZING LOTION: BREAKTHROUGH TECHNOLOGY FOR DRY SKIN

2011-11-07T00:45:00.000-08:00

Discover how Renew intense skin therapy range of products, like no other dry skin therapy, is made to heal, soothe and moisturize dry and even chronically dry skin. Melaleuca's scientists came up with a successful breakthrough technology,that has since become Melaleuca's protected trade secret.

This new discovery finally made it possible for purest, petrolatum and glycerin to mix together in high amounts. Renew Moisturizing Lotion has been clinically proven to outperform the no. 1 dermatologist recommended brand. Renew Moisturizing Body Wash perfectly complements Renew Moisturizing Lotion to provide significant relief to chronically dry skin and dry skin associated with eczema.

ROSEHIPS EASES ARTHRITIS SYMPTOMS

2011-09-26T03:04:00.000-07:00

A herbal supplement made from the seeds of rosehips(Rosa canina) can overcome severity of symptoms in people with osteoarthritis (OA) of the knee and hip, according to a study published in the Scandinavian Journal of Rheumatology.(2005:34:302-8).

OA, a degenerative disease common in older people, is characterized by progressive loss of cartilage in the joints and symptoms such as pain, stiffness and reduced mobility.

Rose hips are the bright red fruit of a wild rose bush, known for their high vitamin C and bioflavonoid content. Popularly used to prevent and treat colds and asthma, a recent study found that powder of rose hips has anti-inflammatory properties.

Three clinical trials involving the same preparation of rosehips concluded that rose hips are an effective pain reliever. A total of 306 patients participated in the three clinical trials, two of the studies were from Denmark and one involved patients from Norway. The results of this study show that rosehips powder can alleviate symptoms of OA and increase mobility in arthritic joints.

For more info: please read http://www.ncbi.nlm.nih.gov/pubmed/16195164

XAMIOL: A NEW TREATMENT OPTION FOR SCALP PSORIASIS

2011-09-19T22:49:00.000-07:00

Xamiol is a new once-daily topical treatment developed especially for scalp psoriasis in patients over the age of 18 years. Xamiol contains a vitamin D analogue (calcipotriol) and a corticosteroid (betamethasone) in a gel formulation. The complementary modes of action of the two active ingredients support a fast onset of action and results in the long term when used as recommended.

Xamiol should be applied to the affected areas of the scalp once daily for 4 weeks. After this period, repeated treatment with Xamiol can be initiated. Xamiol is to be used once-a-day, for convenience, Xamiol can be applied NIGHTLY as part of your bedtime routine.

All the affected scalp areas may be treated with Xamiol. When using calcipotriol-containing products, the maximum daily dose should not exceed 15g (app. 4 teaspoons), and the maximum weekly dose should not exceed 100g (app. 25 teaspoons).

People react differently to treatments. Most people see results within 1-2 weeks of treatment. It is, however, important to continue with the treatment as described by your doctor. When you have been cleared from psoriasis, you may not need the treatment for a period of time. You can safely stop the treatment and start it again when necessary, as described by your doctor.

POLYPEPTIDE-K

2011-09-18T03:00:00.000-07:00

Polypeptide-k acts as natural plant insulin (does not cause hypoglycemia in diabetic patients).

Polypeptide-k is a protein molecule made up of 18 amino acids (sequence is similar to bovine insulin) and have been patented worldwide (US patent number:6831162).

It works very well in pre-diabetes, diabetic, and cardiovascular cases.

It showed no cross reaction with insulin.

It has no known toxicity if overdose.

It has no known side effects with anti-diabetic drugs.

Supplementation rightfully will also help to reduce insulin resistance. One of the most commonly used food/herbal treatment is BITTER GOURD. Dr. Pushpa Khanna, a Nobel Prize winner and renowned researcher from India, found Polypeptide-k which can:

1.Activates inactive insulin

Polypeptide-k attaches to inactive insulin (normally present in diabetics) and this causes it to become active again. Insulin helps to metabolize sugars into energy.

Polypeptide-k rejuvenates the pancreas over a period of time.

2.Decreases insulin resistance and improves overall metabolism.

3.Improves metabolism of fat.

SUGARD is made from patented Polypeptide-k, a sequence of 18 amino acids extracted from the seeds of bitter gourd (Momordica charantia).

Who can benefit from Sugard?

1.Diabetic patients / on medications - Type 1 and Type 2.

2.Impaired Glucose tolerance (IGT) individuals .

3.People who have cravings for sweet food (junk food, desserts, sweets, canned drinks, etc).

4.Family history of diabetes .

5.Frequent meals high in refined sugars .

6.People who are obese .

7.People who have hypertension / high cholesterol .

Only 1 sachet before each meal or as needed..

The Prime Sugard is now available in Malaysia, the price is RM75/30sachets

BARAKA: NIGELLA SATIVA OIL EXTRACT

2011-09-16T22:08:00.000-07:00

Baraka,the only pharmaceutical standard designed Food Supplement with Nigella Sativa Oil Extract to maintain good health.

Many centuries ago , Nigella Sativa ,or black cumin, or known as Habbatus-Sauda is regarded by many as a panacea for many illness. Habbatus-Sauda seeds have been known to have the high remedial quality. Remedy asthma and allergies, and also banish fatigue.

Baraka is a pharmaceutical quality product with endorsement of Ministry of Health Malaysia and NPCB.

Each capsule contains: Nigella Sativia Oil Extract 450mg

Usage: 2 to 6 capsules daily.

{Sabda Prophet Muhammad S.A.W,"Keep your treatment with Habbatus-Sabda, as it contains a cure for all illnesses except death" ,related by Al-Bukhari.}

Nigella sativa oil (not black cumin seed oil) contains nigellone, which protects guinea pigs from histamine-induced bronchial spasms(perhaps explaining its use to relieve the symptoms of asthma, bronchitis, and coughing).
The presence of an antitumor sterol, beta-sitosterol, lends credence to its traditional use to treat abscesses and tumors of the abdomen, eyes, and liver.
N. sativa oil has been reported to be effective in treating opioid dependence.
N. sativa also has been reported to reduce calculi formation in rats' kidneys.
The oil contains melanthin, nigilline, damascene and tannin. Melanthin is toxic in large doses and nigelline is paralytic, so this spice must be used in moderation.

Researchers at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have found that thymoquinone, an extract of N. sativa seed oil, blocked pancreatic cancer cell growth and killed the cells by enhancing the process of programmed cell death, (apoptosis), acting as an HDAC inhibitor. While the studies are in the early stages, the findings suggest thymoquinone could eventually have some use as a preventative strategy in patients who have gone through surgery and chemotherapy or in individuals who are at a high risk of developing cancer.

Nigella Sativa currently has five (5) FDA separate patents in the U.S. and one (1) in the UK for the treatment of:
1.Diabetes (US 6,042,834)

2.Inhibition of cancer cell growth (US 5,653,981)

3.Improvement of the Immune System (US 5,482,711)

4.Viral Infections (US 6,841,174)

5.Psoriasis (US 6,531,164)

6.Asthma (UK - EP1709995)

QUTIE COAT:WHITE REVOLUTION---A 40 SECONDS MIRACLE

2011-09-12T00:44:00.000-07:00

The benefits of Quite Coat:

Melanin Inhibition
Double Whitening Effect
Deep Skin Moisturizing
Fine lines Reduction/anti-wrinkling
Pore minimization
Lightens scars, dark spots & uneven skin tone
Nutrition Replenishing

5 main ingredients in Quite Coat:

Tranexamic Acid:
Whitening ingredient that infiltrates into the skin to whiten rapidly.
Effectively inhibits the production of Melanin by suspending the production of the tyrosine enzyme.

Hydrolysed Silk Protein
Size of the molecule is 1/20 times smaller compared to other whitening products, which allows immediate penetration into the skin.
Excellent moisturizing retention, giving you superior elasticity of skin & optimum moisture balance.
Prevents dehydration of skin

Arbutin
Extract of bearberry plant with natural double-action whitening agent
Effectively prevent activity of tyrosinase in the skin, hence inhibits the formation of melanin pigment
Protects the skin against damage caused by free radicals .

Vitamin C/Ascorbyl Tetraisopalmitate
An antioxidant & whitening agent with both anti-aging & anti-acne capabilities
Effectively promotes collagen production
Tones and tightens the skin to help repair the appearance of fine lines and wrinkles
Reduces skin discoloration due to sun damage, aging and acne scarring
Improves elasticity & moistures for dry skin .

Argireline
A non-toxic & non-irritant compound that relaxes tension of facial muscles
Effective in reducing the depth of fine lines & wrinkles
Accelerates collagen synthesis to provide you with anti-wrinkling & anti-inflammatory effects .

Usage: Cleanse, apply Quite Coat, and massage for 40 seconds.Rinse after 3 minutes. For rapid lightening of the skin while maintaining high moisture levels, use 2-3 times weekly.

Quite Coat is now available in Malaysia. The price is RM 229 only, much more cheaper than other rivals that contains Tranexamic Acid..

WATER-SOLUBLE SOLUOMEGA---THE BIOACTIF(BIOLOGICALLY ACTIVE)FISH OIL

2011-09-10T00:11:00.000-07:00

Consistent with the science,Nuvaceuticals proudly introduces SoluOmega Fish Oil. SoluOmega is a water-soluble fish oil supplement containing 50% concentration of the Omega 3 fatty acids EPA and DHA.

Using a proprietary Lipisol technology, scientists have successfully overcome the challenges faced by conventional fish oils. When SoluOmega comes into contact with water, it remains dispersed as fine oil droplets of sub-micron size thus rendered water-soluble.

The SoluOmega breakthrough science is of important benefit to the following:

Anyone requiring high omega 3 dosing.

Anyone wanting a healthier omega 3 formulation.

Anyone on weight control.

Elderly

Anyone with compromised fat digestion conditions whether from aging,disease,medication or surgery including:poor liver function,poor gall bladder function,poor pancreatic function(e.g.diabetes).

How will I know whether my fish oil is water-soluble?

Take the fish oil capsules and drop it into water.

Give it a light stir.

Water-soluble fish oils completely dissolve in water whilst non water-soluble fish oils form a layer of oil on the water surface.

RAINFOREST MISAI KUCING PLUS : NATURAL ANTI-INFLAMMATORY

2010-12-19T02:40:00.000-08:00

Misai Kucing Plus contains the herbal extracts of:

1.Orthosiphon aristatus

2.Centella asiatica

3.Zingiber officinale

4.Curcuma longa

In South East Asia the herb Misai Kucing (Orthosiphon aristatus) has a long history of use as a safe and effective herbal diuretic, blood purifier and anti-inflammatory in arthritic conditions. It helps to remove excessive metabolic wastes and acids that lead to arthritic complaints. Gotu Kola (Centella asiatica), Turmeric (Curcuma longa) and Ginger (Zingiber officinale) contain potent anti-inflammatory and analgesic compounds and act as circulatory stimulants to provide natural and lasting relief from joint pains.

Therefore, Rainforest Misai Kucing Plus is helpful in relieving joint pains that associated with arthritis and gout.

NARCOX :NATURAL COX-2 INHIBITOR

2010-12-11T04:55:00.000-08:00

NARCOX is a natural long-term pain relief supplement with a patented Belgian technology called CCE 4800. CCE stands for ‘Caged Curcumin Extract’. CCE 4800 contains curcumin extracted from Curcuma longa, commonly known as turmeric. Curcumin is one of nature’s most powerful anti-inflammatory agents. By using a patented Belgian technology, the curcumin molecule is caged in a polysaccharide (natural starch) called ?-cyclodextrin to increase the absorption of curcumin by 4000x.

NARCOX is proven to offer a completely safe and effective relief for joint and muscular pain caused by swelling and inflammation, without any side effects.

NARCOX is a solution for those who suffer from severe arthritis and injuries from sports or accidents. It is an alternative for those who are taking drugs and medication for their pain but are looking for a safer solution that doesn’t pose any side effects in the long run.
The amount and consumption frequency of drugs or medications that cause side effects can be reduced by complementing them with NARCOX.

NARCOX’s source of curcumin is derived from organically cultivated turmeric plants. NARCOX has been sold in North America and Europe for almost 5 years. Today, NARCOX is available in all leading pharmacies in Malaysia.

There is no issue of NARCOX being taken together with other painkillers. NARCOX can be used to substitute or complement your prescribed painkillers. It is not necessary for you to take other painkillers if you find that NARCOX alone is providing sufficient pain relief. But certain individuals may need to take a small dose of painkillers with NARCOX to manage their pain. This is beneficial as long term consumption of painkillers such as NSAIDs (non-steroidal antiinflammatory drugs) can cause side effects including strokes as well as cardiovascular and gastrointestinal problems.

NARCOX should be taken, or its dosage increased, when the pain is aggravated. However, do note that NARCOX cannot eradicate pain permanently but daily consumption can keep the pain at a minimal level.

For a better absorption, it is advisable to take NARCOX 30 minutes before taking your meal or medication. This is also to ensure that the medication does not affect the efficacy of NARCOX.

The efficacy of NARCOX varies from one individual to another and depends on the severity of the pain. However, there should be significant pain relief within 2 weeks if NARCOX is consumed according to the recommended dosage.

RSP for NARCOX is RM75 for 30's

BLACKMORES GLUCOSAMINE 1500MG

2010-12-01T23:13:00.000-08:00

Research shows that glucosamine sulphate may help reduce joint inflammation and swelling, increase joint mobility and provide temporary relief of the pain of osteoarthritis.

Researchers found that 55% of patients with osteoarthritis of the knees had a clinically significant improvement in pain and mobility after a period of four weeks using glucosamine sulphate 1500mg daily.

I prefer people to take Glucosamine 1500mg instead of 500mg because one-a-day high strength tablet may contribute to good compliance.

The only problem for Blackmores glucosamine 1500mg is the tablet is quite huge.

GARDASIL:NEW INDICATION IN MALAYSIA

2010-11-28T01:40:00.000-08:00

MSD in Malaysia announced that the National Pharmaceutical Control Bureau (NPCB) of Malaysia has approved a new indication for Gardasil in September 2010.

In addition to the current indications of Gardasil in girls and women aged 9-26 years old for the prevention of cervical cancer, vulvar and vaginal cancers and genital warts caused by Human Papillomavirus(HPV) 6,11,16 & 18, Gardasil is now also indicated in BOYS and MEN, 9 to 26 years of age, for the prevention of genital warts (condyloma acuminata) caused by HPV types 6 and 11.

Gardasil is now indicated for BOTH MALES AND FEMALES aged 9-26 years old.

DetoxiComplex:NOT ONLY COLON CLEANSING BUT FROM WHOLE BODY

2010-11-26T22:37:00.000-08:00

DetoxiComplex is a blend of high quality fibers, prebiotics and probiotic, natural herbs (Ganoderma), nature greens (organic spirulina) and other natural ingredients as patented formula that help to achieve optimal results. With its anti-oxidant delicious black currant taste, it provides more than a tasty treat!

DetoxiComplex™ contains :

Probiotics and prebiotics (FOS) that can enhance the digestion and absorption of nutrients, helps boost the immune system.

Soluble and Insoluble fiber that keeps digestive system healthy and function properly.

Indoor cultivation Ganoderma (magic mushroom) helps eliminate toxins accumulated inside body through intake of various western medication, antibiotic, pain killers and anti inflammatory medicines. It has strong detoxification effect to maintain body balance.

Organic Spirulina as one of the super foods that aid heavy metal detox for removing toxins such as mercury, and radioactive substances from the body. It also helps to reduce weight.

Psyllium husk promotes regularity and easy toxins elimination, reduce problems with diarrhea or loose stools, protect the health of the colon.

Detoxification is a very unique experience for every individual. Everyone is encouraged to detoxify every month due to pollutions and chemicalized diet we eat every day.

In fact, every individual reacts differently during detoxification period. Some may experience several short-term unpleasant reactions but this is absolutely normal process because it is actually a sign that the body is dumping toxins into the blood stream for elimination.

But DetoxiComplex ™ is a mild and gentle full body detoxification program which is formulated to help user to detoxify easily and refueling body with nutrients at the same time. At the end of the program, user will not only restore health but also feel rejuvenated and energized! Many have reported weight loss after using Detoxification™!

Recommended Selling Price: RM125/28sachets

PKR's LOGO COPIED BY XEPA SOUL???

2010-11-12T19:26:00.000-08:00

There is a logo of eye drops just like PKR's logo. Some people joked and said it's a product that manufactured by PKR. . In fact, this is xepa soul's normal saline eye drop, it's indicated for eye dryness. . It has been using this logo before the existence of PKR.

FORSLEAN PLUS: FAT BURNING FORMULA

2010-09-24T21:56:00.000-07:00

The mechanism of action of forskohlin does not entail the activation of adrenergic receptors.

Forskohlin is a known blood pressure lowering agent and is used in the management of hypertension, including ocular hypertension that leads to glaucoma.

Preliminary studies in humans have shown that forskohlin increases the contractility of the heart muscle without increasing oxygen consumption and that it is a vasodilator.

Forskohlin has been shown to inhibit platelet aggregation further validating its beneficial cardiovascular effects.

Clinical studies revealed that forskohlin, in the patented ForsLean® composition, in daily doses of 50 mg for 12 weeks, did not cause adverse effects on the systolic/diastolic blood pressure and the pulse rate.

Forskohlin is known to regulate the secretion of insulin, thereby helping to maintain healthy blood sugar levels.

Forskohlin, in the patented ForsLean® composition, had an LD50 greater than 2000 mg/kg and may therefore be considered safe for use by most healthy people.

As with all other supplements, people taking medications for asthma, hypertension, hyperthyroidism and related conditions as well as those suffering from ulcers or low blood pressure conditions should exercise caution and seek medical supervision.

Forslean plus now is available in leading pharmacies in Malaysia.

RSP is RM 108 for 60's.

WHY ORIGENPLUS COLLAGEN?

2010-09-18T05:32:00.000-07:00

5000mg low molecule size deep sea fish collagen imported from Japan.

ORIgenPlus Collagen contains premium low molecular weight collagen derived from deep sea fish which is 1.5 times more absorb-able by human body than other derived other derived collagen such as animal or plant collagen. In addition, every sachet of 30gm ORIgenPlus equals to our daily requirement of 5000mg collagen which is approximately 2 standard.

High level of Vitamin C (508mg) in every sachet.

Vitamin C helps promotes healthy skin. It plays an important role in supporting the absorption of collagen. The ascorbic acid contained in Vitamin C is highly recommended for people who have wrinkles or fine lines. Vitamin C can play an important role in preventing free radical damage in the skin cell. In fact, Vitamin C is one of the best antioxidants that aids damaged skin, like scar tissue.

Powerful anti-aging Beta carotene.

Beta carotene found in carrots, fruits and green leafy vegetables, is a powerful antioxidant. It is an essential nutrient in maintenance of healthy skin. Beta carotene is also known as action against skin damage from exposure to sunlight.

High quality Dextrose mono-hydrate.

Dextrose Mono-hydrate provides energy source for blood stream and other bodily functions which is important in maintenance of healthy skin and balance up the level of body heatiness. The body heatiness can cause acne and pimples.

NiQuitin Lozenge 2mg or 4mg

2010-09-11T21:44:00.000-07:00

Step 1:1 lozenge every 1-2 hours for weeks 1-6, 9 lozenges per day minimum is recommended.

Step 2:1 lozenge every 2-4 hours for weeks 7-9.

Step 3:1 lozenge every 4-8 hours for weeks 10-12.

Users should not exceed 15 lozenges per day

After week 12, 1-2 lozenges per day may be taken on occasions when quitters are strongly tempted to smoke.

Additional information is available at http://www.niquitin.com.my/ or from your local healthcare pharmacy.

NiQuitin Patch

2010-09-05T02:29:00.000-07:00

For those smoke 10 or more cigarettes a day, they may start with 21 mg patch 3-step regimen.

For those smoke fewer than 10 cigarettes a day, they may start with 14 mg patch 2-step regimen.

3-step Regimen starting with 21mg patch:

Step 1: 21mg for 6 weeks

Step 2:14mg for 2 weeks

Step 3: 7mg for 2 weeks

2-step Regimen starting with 14 mg patch:

Step 1: 14mg for 6 weeks

Step 2: 7mg for 2 weeks

Patches may be worn for 16 hours (removed before bed) or for 24 hours.

Patches can be used beyond 10 weeks if needed to remain cigarette free.

NiQuitin and Nicorette are therapeutic nicotine

2010-08-13T04:53:00.000-07:00

Therapeutic Nicotine or Nicotine Replacement Therapy does not contain the harmful tars and gases found in cigarette smoke.

It binds to the same brain receptors as the nicotine in cigarettes. It can gradually reduce the receptor's demand for nicotine over time and helps reduce withdrawal symptoms such as cravings, anxiety and irritability.

Therapeutic Nicotine is clinically proven that will help smokers quit smoking, it doubles the chances of quitting smoking. It provides 24 hour protection even from tough morning cravings. It will relieve cravings in minutes.

In Malaysia, Nicorette is available in medicated chewing gums form whereas NiQuitin is newly launched recently and available in lozenge form and patch.

YAZ: Drospirenone/Ethinylestradiol 3mg/20mcg

2010-08-06T04:42:00.000-07:00

YAZ is an ultra low dose once daily combined oral contraceptive containing 3mg drospirenone and 20mcg ethinylestradiol. It is administrated in a regimen of 24 days of active tablets, followed by a 4 day hormone free interval using inert tablets (24/4 regimen).

Drospirenone is the newest synthetic progestogen (a spironolactone analogue) that resembles endogenous progesterone and exhibits anti-mineralcorticoid and anti-androgenic properties, in addition to progestogenic activity. Ethinylestradiol is a commonly used synthetic oestrogen. As with other combined oral contraceptives , YAZ prevent pregnancy by inhibiting ovulation and exerting peripheral contraceptive effects.

Clinical trials indicated that YAZ, in a unique 24/4-day regimen, is a good contraceptive option providing 99% contraceptive protection.

Besides oral contraception, YAZ is indicated for treatment of emotional and physical symptoms associated with Premenstrual Dysphoric Disorder ( a severe form of PMS) and treatment of moderate acne vulgaris.

The new 24/4-day regimen of YAZ helps reduce hormonal fluctuations, while extending the anti-mineralcorticoid and anti-androgenic benefits of drospirenone over three additional days, compared to the 21/7 regimen.

YAZ is well tolerated, with adverse events generally typical of those experienced with other combined oral contraceptives.

ZYDENA 100mg/200mg: THE NEW PDE5I FOR ERECTILE DYSFUNCTION.

2010-06-14T02:38:00.000-07:00

Zydena is the 4th therapeutic oral new drug for erectile dysfunction in the world. Zydena, which is new drug for ED, induces strong erection by selective inhibition of cGMP-specific PDE5 which is mainly presented in corpora cavernosa.

88.5% of the ED subjects shows improvement of erectile function. In phase III clinical trial at 13 institutions including Seoul National University Hospital for 6 months with 270 ED subjects, 81.5%(zydena 100mg)/88.5%(zydena 200mg) of subjects showed improved erectile function in Global Assessment Question.

Zydena has adequate duration (8-12 hours) of drug action. In the result of clinical pharmacokinetics, Tmax of Zydena is 1 hour and T1/2 is 10-12 hours. Zydena shows high intercourse success rate even at post 8-12 hours from administration of Zydena 100mg in phase III clinical trial.

Its good tolerance and safety were confirmed in phase I,II and III clinical trials. the major adverse drug reactions were flushing, nasal congestion, ocular hyperaemia, headache and dyspepsia, and most of these reactions, which were reported during clinical trials, were slight and voluntarily gone with no therapy. Thus, it is confirmed that Zydena has good safety and tolerance.

Zydena has no inhibitory action to PDE 11 and no report has been made about myagia,back pain and testis toxicity. Zydena has no inhibitory action to PDE11, which is heteoenzyme of PDE, and no report has been made about myalgia, back pain and testis toxicity during clinical trials.

WHAT CAN KRILL OIL DO FOR YOU?

2009-10-10T05:21:00.000-07:00

A healthy heart

Relief of normal PMS(Premenstrual Syndrome) symptoms:improves physical and emotional symptoms;reduces breast tenderness,stress,irritability,depression,joint discomfort and bloating;improvements on weight gain,abdominal discomfort,and swelling.

Improves quality of life: increases memory,concentration,and alertness; improves emotional and physical health;improves calmness and tolerance of stress.

Strengthens your immune system.

Healthy brain and nervous system function and development.

Protection of cell membranes.

Improves energy;benefits childhood learning and behavioral disorders.

Decreases pain and joint discomfort; reduces chronic inflammation C-reactive protein (CRP); increases joint flexibility.

Lowers cholesterol and triglycerides, elevates HDL levels, and lowers blood sugar.

Has anti-inflammatory and powerful anti-oxidant properties.

Protects the skin from UV damage.

Tocomin®SupraBio™ Improves Arterial Compliance

2008-12-14T01:07:00.000-08:00

Carotech is pleased to announce data from a human study recently published in Archives of
Pharmacal Research (Sept 2008:31(9), 1212-7) which demonstrated Tocomin®SupraBio™ (a self emulsifying palm tocotrienol complex) was able to reduce arterial stiffness in healthy adults after 2 months oral supplementation.

In this blinded endpoint clinical trial conducted by researchers in The University of Science, Malaysia (USM), 36 healthy volunteers were randomized to receive either the placebo, 50mg, 100mg or 200mg self emulsifying tocotrienol rich vitamin E (Tocovid™SupraBio™, supplied by Hovid Bhd.) daily for 2 months. Measures of arterial compliance (carotid femoral Pulse Wave Velocity and Augmentation Index) and other parameters such as blood pressure and serum lipid profiles were taken before and after treatment. Plasma tocotrienols concentration was also measured.

The results showed that treatment with self emulsifying tocotrienol rich vitamin E produced
significantly higher plasma concentrations of tocotrienols compared to placebo. After 2 months of
supplementation, statistically significant improvement in Augmentation Index (up to 8.7% reduction from baseline) was observed in all the tocotrienols supplemented groups. Significant improvement in Pulse Wave Velocity (up to 10% reduction from baseline) was also seen in subjects who received 100mg and 200mg self emulsifying tocotrienols rich vitamin E. However, treatment has no effect on blood pressure, serum total cholesterol and LDL-cholesterol.

Decreased arterial compliance or increased arterial stiffness is a predictor of cardiovascular events even in healthy individuals. A reduction in both Augmentation Index and Pulse Wave Velocity, as showed by supplementation with self emulsifying palm tocotrienols complex, indicates better arterial compliance, thus reducing the risks of cardiovascular diseases.

“This study showed that tocotrienols reduced arterial stiffness, in addition to other previously
reported cardiovascular benefits including cholesterol lowering and antiplatelet effects.” says WH Leong, Vice President of Carotech Inc.

“SupraBio™, the patented self-emulsifying formulation enhances oral absorption of tocotrienols
independent of food intake.” adds WH Leong.

TOCOTRIENOLS STUDIES SHOW EFFECTIVENESS AGAINST BALDNESS

2008-10-04T00:39:00.000-07:00

A new 8-month study showed that TocovidTM SupraBioTM 50mg oral supplementation
promotes hair growth in both men and women suffering from androgenetic alopecia
(pattern baldness).
Pattern baldness condition is said to affect about 50 percent of men and women over the
age of 40, and is said to be caused by three independent factors, testosterone levels,
genetic disposition and advancing age.
28 volunteers with mild to moderately severe ongoing hair loss completed the 8-month
study conducted at the School of Pharmaceutical Science, Universiti Sains Malaysia.
The volunteers receive the TocovidTM SupraBioTM 50mg or placebo, administrated twice
daily. Hair counts and weight of hair in pre-selected evaluation area were measured
before and after every month initiation of the study.
An average of 41.8% increase in the number of hair was observed after 8-month tocotrienol
supplementation, with
· 8 volunteers (40%) showed > 50% hair growth
· 1 volunteer (5%) showed > 25-50% hair growth
· 9 volunteers (45%) showed > 10-25% hair growth
· 1 volunteer (5%) showed > 10% hair growth

The unique of the TocominTM SupraBioTM system provide 250% increase in absorption of tocotrienols, hence to achieve therapeutic levels in the bloodstream at a lower dosage of the
supplementation. It promotes the absorption of tocotrienols via the lymphatic system, whereas it does not depend on dietary fact or food intake. Plus, it allows consistent and rapid
transport of tocotrienols into the blood thus the maximum peak is reached much quicker.
The formulation is a natural full spectrum palm tocotrienol complex that is a more potent form Vitamin E with unique health benefits, which not only has shown good results in the treatment of pattern baldness; tocotrienols come in both natural and synthetic forms and are also to reduce the effect of free radicals, with studies pinpointing that this property gives the compound an anti-cancer effect, maintain healthy cholesterol level and prevent cardiovascular disease.

FISH OILS LOWERED CARDIOVASCULAR RISK DESPITE AGGRESSIVE THERAPY WITH STANDARD PHARMACOTHERAPY

2008-09-28T00:11:00.000-07:00

The JELIS- The Japan EPA Lipid Intervention Study randomized 18645 patients with hypercholesterolemia (of which 70% were women: age 61 years) to statin alone or statin and pure EPA. EPA reduced major adverse cardiac events by 19%.

The MAYO article also commented: Omega 3 fatty acid supplementation lowered cardiovascular risk both in GISSI-P and JELIS showed that despite aggressive therapy with standard pharmacotherapy(e.g. statins, aspirins, beta blockers, and ace inhibitors). Combination therapy with omega 3 fatty acids and a statin is a safe and effective way to improve lipid levels and cardiovascular prognosis beyond benefits provided by statin therapy alone

FISH OIL SUPPLEMENTATION REDUCES CARDIOVASCULAR EVENTS BETWEEN 19 TO 45% AND DEATH BETWEEN 28 TO 45%

2008-09-21T21:46:00.000-07:00

In a recent MAYO clinic review article quotes "that the most compelling evidence for the cardiovascular benefit provided by omega-3 fatty acids comes from large controlled trials 32000 patients demonstrated in reduction in cardiovascular event between 19% to 45%.

In the DART Trial, omega 3 fatty acids, either in the form of oily fish or fish oil capsules, "Treatment reduced 2 year all cause mortality by 29% in post myocardial (MI) patients"

The GISSI-P study randomized 11,323 patients who had experienced a myocardial infarct to omega 3 acid ethyl esters (1 capsule, providing 850mg of DHA/EPA) or usual care. "Treatment reduced death from any cause by 28% after 4 months. Treatment reduced sudden cardiac death by 45%."