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The risk of developing pneumonia is 100 times higher in people who were infected with influenza

2013-08-03T08:29:00.002-07:00

The link between influenza and pneumococcal pneumonia is clearly shown in our study. In short, our analysis revealed a transient but significant - about 100 times - increase the risk of pneumococcal pneumonia following influenza infection, "- said the study's lead author Pezhman Rohani of the University of Michigan.
Previously, the relationship between influenza and pneumonia could be established only in animals. Rohani and his colleagues created a computer model of the spread of bacterial pneumonia in humans and tested various hypotheses that describe the role of influenza in the process. The scientists assessed the compliance of each hypothesis, epidemiological reports for 20 years, from 1989 to 2009, in which the weekly recorded cases of hospitalization for influenza and pneumonia in Illinois.
These observations confirm the hypothesis that the increased susceptibility of patients with influenza to the agents of pneumonia lasts for 5-7 days after infection. The scientists also found that at the peak of the epidemic season flu was the cause of 40% of the cases of pneumonia, but the average for the year, this value does not exceed 10%. Perhaps that is why earlier researchers failed to show the relationship between the two diseases.

High-calorie diet can contribute to the development of cancer

2013-08-03T08:27:00.001-07:00

Scientists in Japan have found that high-calorie diet alters the intestinal microflora, which may cause cancer of the liver and gastrointestinal tract.

Naoko Ohtani of the Cancer Institute in Tokyo (Japan) and her colleagues found that microorganisms can indirectly contribute to the development of cancer, watching her work in the intestine of mice during the transition to high-calorie diet. In these experiments, doctors noticed that rodents, overweight, suffer more from cancer than their cousins in the control group.
Scientists intrigued by this fact, and they decided to find the cause of this by analyzing the differences in the microflora and the genomes of mice from these groups. For example, some bacteria in the intestines of rodents with overweight behaved extremely unusual - they synthesized molecules of deoxycholic acid. It belongs to bile acids required for some absorption of nutrients, including vitamins A, D and E. Typically, they are not destroyed in the gut together with the blood and the liver.
Deoxycholic acid is a carcinogen that can cause damage and mutations in the DNA. This happened with the mice - when scientists destroyed the "bad" bacteria, the incidence of tumors in the liver and intestine decreased significantly, almost reaching the values characteristic of the control group. This fact shows that the high-calorie diet can actually contribute to the development of cancer, doctors conclude.

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The Russian company will hold a U.S. trial of the drug for cancer

2013-06-20T09:19:00.000-07:00

Russian biopharmaceutical company "Inkuron" developing innovative anti-cancer drugs, has received approval from the U.S. Administration of Quality Supervision Food and Drug Administration (FDA) for clinical trials of the drug CBL0137 for the treatment of patients with advanced malignant tumors, reports of "RVC".
"Receiving FDA approval for the study of innovative molecules in the USA Russian startup is a precedent in the case of the Russian practice," - said General Director of Management Company "Bioprocess Capital Partners" Vladimir prostheses, which is cited in the report.
"Inkuron" - a Russian company, founded in 2010 by the "Bioprocess Capital Ventures", created with the participation of RVC capital and Vnesheconombank, and private investor Cleveland BioLabs. The company is a member of the project "Skolkovo". "Inkuron" is developing a fundamentally new anti-cancer drugs based on Kuraksin - small molecules with potentially wide range of therapeutic applications. Kuraksin may also be used to treat certain autoimmune diseases and inflammatory conditions.
Management Company "Bioprocess Capital Partners" is the trustee of the fund, "Bioprocess Capital Ventures." The Fund invests in innovative projects in the field of biotechnology and fine chemistry, the size of the fund - three billion rubles.

People may grow back severed fingertips thanks to stem cells

2013-06-20T07:56:00.002-07:00

U.S. scientists have found that the tips of his fingers cut off in mammals, including humans, can grow again thanks to the stem cells that are found in the nail bed, reports RIA "Novosti" with reference to an article in the journal Nature.
Mayumi Ito and his colleagues conducted a series of experiments on mice on the regeneration of the fingertips. They found that at the base of the nail is a small group of stem cells, through which the nail is growing. Its growth is controlled by a family of proteins Wnt, and if this control mechanism is broken - the nail will not grow.
As shown by the scientists, the same mechanism is responsible for the restoration and the fingertips. After the amputation, Wnt proteins are activated in the epithelium, which lies beneath preserved piece of the nail, and are attracted to the damaged area of the nerve cells. They start the growth of germ cells of connective tissue, which then turn into bones, tendons and muscles. Through this mechanism, the tips of the fingers in mice fully recovered within 5 weeks. If the mice were amputated too much of a finger nail from where almost nothing to do but did not start the regeneration process. In this case, the scientists managed to run it by stabilizing the base of the nail protein beta-catenin, which acts as a transmitter of signals between proteins Wnt.
Scientists believe that maybe this mechanism is also in humans, and the results will help in the development of ways to restore amputated limbs.

Geneticists have deciphered the genome of the pathogen medieval leprosy

2013-06-20T07:55:00.000-07:00

Johannes Krause of the University of Tübingen (Germany) deciphered the genome sticks Hansen (Mycobacterium leprae), the causative agent of medieval leprosy.
Chronicles indicate that leprosy was widespread in Europe in the first half of the Middle Ages. By the late 16th century, it came to an epidemic, and the reasons for this remain unknown.
Krause and his colleagues studied the remains of the inhabitants of Sweden, Denmark and England, who died of leprosy in the 11-14 centuries AD. Scientists separated the small pieces from the teeth, and tried to remove the fragments of bacterial DNA. To their surprise, the Europeans enamel contained a surprising amount of genomic fragments bacilli, ten times more than expected.
This allowed them to recover the complete genome of a microbe with an accuracy higher than the standard for live bacteria to 5 times. The scientists compared the structure of its DNA with the genomes of 11 modern species of Mycobacterium leprae. It was found that the genomes of microbes were virtually identical. This suggests that this microbe was originally highly contagious to humans, but over time it has lost force as human immune system has adapted to it faster than a bacterium

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Doctors have created viruses to fight cancer, using a mathematical model

2013-06-20T07:53:00.003-07:00

"So-called oncolytic viruses attack only certain types of cancer cells. Unfortunately, the cells of the same tumors may differ from each other, and this reduces the effectiveness of the virus. We have accelerated their development by means of a mathematical model, "- said lead author John Bell and Mads Cairn from the University of Ottawa (Canada).
Bell, Karen, and their colleagues were trying to create a virus that can destroy the cell adenocarcinoma of the kidney. According to them, the main problem of such viruses is the variability of cancer cells - they are frequently mutated gene, resulting in a change in the structure of the shell, in which the virus outgrowths distinguishes its goal of healthy tissue.
The authors have solved this problem by developing a special mathematical model. To do this, scientists have compiled a list of genetic differences between healthy and cancerous cells of the kidneys, and identified the most "noticeable" for signs of viruses. Combining these data received biological model that can predict how mutations in the viral genome will influence cells which they infect.
As the researchers note, it has allowed them to identify the most promising "versions" of the virus and test them in mice, instead of looking for them through trial and error.

Scientists have found a way to prevent the harmful effects of alcohol

2013-06-20T07:52:00.000-07:00

When injected into the blood alcohol produces active oxygen, which damages the liver, causing hepatitis and even cirrhosis of the liver. However, until now there was little information on how active oxygen is generated.

South Korean scientists have proven that alcohol causes the production of nuclear hormone receptors ERRy, they have harmful effects on the liver. Thus, the scientists say, if suppress the production of these hormones can prevent liver damage alcohol, allowing you to drink and not worry about the physical effects of alcohol.

The group of scientists including experts from the Korea Research Institute of Bioscience and Biotechnology at Chonnam National University.

South Korea is a country with one of the highest rates of alcoholism in the world. According to various reports, the country is between 7 and 13 places on the use of alcohol

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Geneticists have taken another step toward a new HIV therapy

2013-01-27T04:37:00.000-08:00

Researchers at Stanford University have developed the T-cells that are able to resist HIV, at least in the laboratory, says CBS San Francisco. According to the researchers, this discovery will bring gene therapy for AIDS.

In theory you could enhance any cells that attack HIV. As a result, the virus can not infect immune system. Taking into account that HIV mutates active and able to bypass the security mechanism of the body, scientists have tried to put several "obstacles."

Dr. Matthew Portias says: in the future, standard cocktail of antiretroviral drugs recede into the background. The idea is simple - therapy, which goes in with the use of a single injection.

Doctors will collect the patient's cells, change them, and then introduce back. That's the whole course of treatment. HIV nowhere to perch oneself, and the virus can live in the body. Biological mechanisms themselves will do the job and get rid of HIV.

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Men spend less effort than women, if they need to lose weight

2013-01-27T04:35:00.002-08:00

More difficult for women to lose weight. They have to put more effort to achieve the same result as the men. Scientists from the University of Missouri conducted an experiment. They gathered a group of obese men and women, accounting for them the same weight loss program, writes The Daily Mail.

Professor Jill Keneyli and colleagues tracked the heart rate and a pressure of about 75 people with Type II diabetes. People are offered a program of cardio for 16 weeks. Although all trained with a intensity of training to benefit more men.

Men threw off more pounds, and the recovery time after training decreased. Hence, men and women should train differently. The reason is simple - men have more muscles, and the muscles have higher metabolic rate than fat. Then, men more heart and lungs, as well as hemoglobin.

As a result, even at rest, men burn more calories. That is, men can just train, and women still need to follow the diet (men enough to train at 65%, as women - 85%)

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Designed most optimal treatment for HIV

2013-01-20T01:23:00.001-08:00

If a person starts to give medication immediately after diagnosis "HIV", it can slow down the process of infection, and began a lifelong course of drugs can be postponed, writes The Daily Mail. This, in turn, will reduce the chance of spreading the disease.
Meanwhile, patients usually do not prescribe antiretroviral therapy before their immune systems are seriously damaged. But a team from King's College London offers to give medication at once, in order to reduce the concentration of virus in the blood for up to 60 weeks.
Dr Sarah Fidler and colleagues studied 366 patients with HIV. Some of them were given for 12 weeks medication. The second group received 48 weeks of preparations. The third did not take drugs as long as the concentration of CD4 T cells was less than 350 cells per cubic milliliter of blood (normal concentration of 600 to 1200).
They then began to observe how long it takes for as long as the number of T-cells drop below 350. Another marker was the beginning of life-long course of antiretroviral drugs.
Group of patients received no medication, started life course through 157 weeks after infection. People taking antiretroviral drugs for 12 weeks - 184 weeks of infection. But here are taking medication for 48 weeks passed on lifelong therapy after an average of 222 weeks. And the concentration of T-cells was higher in the latter. Plus, reduce the risk of secondary infections such as tuberculosis.

Solariums dangerous midday sun twice

2013-01-20T01:20:00.003-08:00

About the dangers of tanning salons for skin health, scientists say a long time. Now they have calculated the extent, said The Telegraph. American doctors have even tried to ban solarium minors.

It turns out that the risk of developing skin cancer is twice when people visit the solarium, compared with the same time spent in the midday sun in the Mediterranean. Experts in the person of Professor Harry Moseley of the University of Dundee to check the level of UV radiation at 400 solariums. 9 out of 10 gave higher figures of European safety standards.

Not for nothing, WHO brought it sunroom into a single list of factors triggering cancer with cigarettes. Over the past 30 years, the incidence of skin cancer has increased by four times. It is the most rapidly increasing rates of cancer in the group.

By the way, if a person under 35 goes to the solarium, the probability of melanoma increases by 87%. But independent experts emphasize that sounded data may not be relevant, because the payment was taken in the old statistics.

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Cuba is in the grip of cholera, doctors warn

2013-01-16T10:42:00.001-08:00

In Havana recorded outbreak of cholera. The number of infected people to 51, reports Xinhua. Death yet. The first positive came to the attention of physicians on January 6. These were people who lived in the district of El Cerro and complained of severe diarrhea and vomiting.

Then cholera identified in other parts of the city. This is the second outbreak of cholera in Cuba for about six months. Despite this fact, Cuban experts argue that infection almost won.

Recall: in July 2011, epidemiologists cholera diagnosed in 158 people. Three died. Later it was decided to launch a nationwide campaign against cholera. Now doctors are engaged in active proliferation of drugs.

Cuban Institute of Tropical Medicine Pedro Kouri identified that the strain of cholera, which appeared on the island now, and is similar to the July. Recommendations to tourists and the local population are standard: hygiene, regular hand-washing and use only clean water.

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The increasing pace of mental disorder pushes diabetics to death

2013-01-16T10:41:00.001-08:00

The study showed women 53-100 years 1837, removal of the ovaries increases the likelihood of mental decline in old age, says The Independent. Removal is usually in young women due to cancer. Develops as a result of the operation "surgical menopause." With this type of one-third of the subjects experienced menopause. Women are tested for thinking and memory. It turned out "surgical menopause" at a young age was associated with a more rapid deterioration of the ability to think and certain types of memory. Long-term memory, coupled with the concepts, ideas, and episodic memory concerning any events - that suffer.

Commented research director Dr. Riley Bove, of Harvard Medical School: "Based on these data, we can assume that in this case it makes sense to turn to hormone replacement therapy. Actually, this is also indicated by the results of testing. Therapy can slow the process of deterioration."

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Novo Nordisk invests in the creation of a new R & D-center in China

2012-09-30T00:44:00.005-07:00

Representatives of the company Novo Nordisk announced their intention to invest an additional $ 100 million. U.S. to build its R & D-center in Beijing.

The new building of the research center area of 12 thousand m2 will increase staff scientists from 130 to 200 and increase the scientific potential. This decision was made in the implementation of Novo Nordisk its core strategy, which is to provide opportunities for the entire spectrum of protein in China.

Mads Krogsgaard Thomson (Mads Krogsgaard Thomsen), executive vice president, said that China has a serious scientific study, and by investing in the creation of a new R & D-center, Novo Nordisk plans to use innovative approaches of Chinese scientists.

The current research center has made a significant contribution to the company's portfolio of research in the field of drugs for the treatment of diabetes and biopharmaceutical drugs used in other diseases.

Novo Nordisk was the first multinational corporation, opened a research center in China (1997). The current research center Novo Nordisk was founded in 2002 and over the years it has become one of the leaders in the field of molecular biology, protein chemistry and cell biology.

Those that were born before term pregnancies often occurs with complications

2012-09-30T00:44:00.002-07:00

Prematurely born women have a higher risk of complications during their pregnancy. In addition, for women who were born before 32 weeks, the risk of complications almost doubled. This conclusion Canadian scientists, who published his findings in the Canadian Medical Association Journal.

Researchers in the past have assumed that complications during pregnancy is more common in women born with low birth weight, but so far there have been no studies with a proper number of participants and the correct view of the additional factors. Dr. Anne Monique Newt (Anne Monique Nuyt) from the University of Montreal (University of Montreal) in Quebec and colleagues turned to a database of Quebec newborns, which has been going on for decades. They selected data on 554 women who were born before 32 weeks of pregnancy from 1976 to 1995., 6851 women born between 32 and 36 weeks, and 16 thousand women who were born at term. All the participants of the study gave birth to at least one child between 1987 and 2008. The scientists analyzed the pregnancy each participant for the development of complications such as gestational diabetes and preeclampsia (hypertension, preeclampsia and eclampsia).

After accounting for factors such as age and weight at onset of pregnancy, researchers found that during at least one pregnancy complications developed in 11.7 per cent of women born in the period from 13.2 per cent of women born between 32 and 36 weeks, and 19.9 percent of women born before 32 weeks. The risk of each of the above complications in women born before 32 weeks, significantly higher than the risk for women in the other groups: gestational diabetes - a 2.34 times higher hypertension - 1.56 times more likely, pre-eclampsia or eclampsia - 1, 79 times more often.

The scientists also found that prematurely born women for life in most developing hypertension (1.4 times faster), and type 2 diabetes (0.5 times faster). It is also interesting that these women are much more likely to have at least 12 years of education (44.6 percent versus 41.7 percent in the group born between 32 and 36 weeks and compared with 36 percent in the group born at term).

According to scientists, the mechanism of effect of premature birth on the long-term effects on women's health is not yet entirely clear. Apparently, in preterm infants impaired microcirculation and metabolism of insulin. In the future, this leads to the development of cardiometabolic complications in pregnancy. Scientists urge obstetricians sure to take into account whether a pregnant woman was born in time to be alert to possible complications.

These geneticists and archaeologists about the ancestors of man finally coincided

2012-09-23T02:50:00.004-07:00

Previously, archaeologists can learn about the life of human ancestors only the bones, tools and implements, but from 1960 a stronger position in archeology began to take DNA studies. In-depth research geneticists sometimes offered their version of events other than the opinions of archaeologists. Now archaeologists and geneticists were finally able to get the same information about the study and confirm each other.

The situation changed with the Restatement genetics method for determining the frequency of mutations in DNA. This frequency - a sort of molecular "clocks" that allow us to calculate the exact age of the genetic type. The method is simple: the number of different nucleotides in the DNA of the two species shows how much time has passed since he was alive common ancestor of these species. To make the calculations as accurate as possible, geneticists need to know the rate at which changes in DNA nucleotides. Previous studies suggested that the rate of change of nucleotides - 1 mutation in one billion years. However, recent studies have shown that in human DNA nucleotide mutates every 1 time in 2 billion years, ie molecular "clock" actually work 2 times slower than previously thought.

Therefore geneticist Oylin Scully (Aylwyn Scally) and his colleagues at Wellcome Trust Sanger Institute in Hinxton, UK, re-counted data obtained before the ancestors of man, based on a new rate change nucleotides. They studied DNA samples from bones belonging to Homo heidelbergensis, grandparent Neanderthals. According to archaeologists, the age is 400-600 thousand years, and that was when there was an offshoot of the ancestors of modern humans. Earlier Geneticists believe that this event occurred much earlier - 270-435 thousand years ago, but given the newly defined mutation rate of DNA, the researchers came to the conclusion that the separation occurred 600,000 years ago, which fully corresponds to archeologists.

Archaeologist Jeff Rose (Jeff Rose) from the University of Birmingham (University of Birmingham) confident that an agreement between the archaeologists and geneticists - a significant event. It will help to confirm many archaeologists received data. In particular, the earlier genetics estimate that the ancestors of Europeans and Asians left Africa 60,000 years ago, while archaeologists have dated this outcome 100,000 years. Recalculation of genetic data with the new speed of the molecular "clock" shows that this result did not occur 60 and 120 thousand years ago, which coincides with the opinion of archaeologists.

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Roche is recognized as the most sustainable company in the world in the health

2012-09-23T02:49:00.004-07:00

Roche announced that it is the fourth consecutive year, recognized as the most sustainable company in the world in the health sector, according to the index of the Dow Jones Sustainability (DJSI). World and European indices Dow Jones Sustainability (DJSI World and DJSI Europe) track leading indicators, in terms of sustainable development, the companies on the basis of best-in-class approach to environmental, social and economic criteria. Indexes serve as benchmarks for investors, who account for sustainable development in the formation of their portfolios.

"Rating Roche as the most sustainable company in the field of health is based on our ongoing effort to conduct business for the benefit of all stakeholders. Roche is actively tuned to this interaction with the public, patients and the public health system, which allows you to create long-term value for all "- said Severin Schwan (Severin Schwan), CEO of the Roche Group.

"In particular, we have set ourselves the goal of diversification and conservation, which are integrated into the system of material incentives for the company's management, which helps to implement our activities in these destinations. We are also launching new initiatives to expand access to our innovative medicines in emerging markets, to the greatest possible number of people were able to take advantage of our products. At the same time, we continue to remain a world leader in pharmaceuticals and diagnostics, "- said Schwan.

This year, the DJSI assessment process were highlighted measures taken by Roche as a sustainable company. These include strategy Roche's innovation and personalized approach to medicine, which increases efficiency and improves health outcomes. Were also recognized for the development of programs Roche future leaders and human rights, and pilot programs to establish the company in developing a differential pricing in order to substantially increase access to medicines Roche.

In 2009, the company has set a number of corporate objectives, designed for five years, the progress in the attainment of which can be measured by key performance indicators. Roche has also set a goal to diversify in order to increase the percentage of women in key positions at least 50%, as well as the problem of increasing energy efficiency by reducing energy consumption by 10% by 2014 and to optimize the use of energy resources.

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Lack of sleep has a negative impact on the formation of new bone

2012-09-23T02:48:00.000-07:00

Scientists at the Medical College of Wisconsin (Medical College of Wisconsin), United States, found that rats that lack of sleep, there are pathologies of bone and bone marrow. In particular, slowing growth and the formation of new bone, and the bone marrow is reduced fat and doubled the number of precursor cells of platelets. Scientists suggest that similar changes may occur in humans. The results of this study are published in the journal Experimental Biology and Medicine.

A team led by professor of neurology, cell biology, neurobiology and anatomy Carol Everson (Carol Everson) studied the peculiarities of bone tissue in rats chronically enough sleep. They found that at a constant rate of absorption, ie, destruction of bone tissue, these rodents practically stops the formation and growth of new tissue, which leads to increased bone fragility and frequent fractures.

Moreover, scientists have noted changes in the bone marrow. The amount of fat in it has decreased dramatically, and the number of platelet precursor cells grown in 2 times. As a consequence of these changes will not only reduce the plasticity of the bone marrow, but also increased the concentration of platelets in the blood of rats. This, in turn, may increase the risk of thrombosis and even heart attack and stroke.

If the same processes can be observed with a lack of sleep in humans, it may partly explain why the elderly are prone to suffer "senile" insomnia, increased risk of osteoporosis and slow the growth of new bone. But scientists say that in today's society lack of sleep has become quite common for young people. Therefore, they need to consider the consequences of lack of sleep for your health and to review their busy schedules.

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Stem cell research in the United States will again have government funding

2012-09-01T12:44:00.003-07:00

U.S. Court of Appeals recognized the legitimacy of public funding for research on embryonic stem cells. The decision had become final chord in the three-year struggle of the National Institutes of Health (National Institutes of Health, NIH) with community organizations trying to ban the use of embryonic stem cells on ethical grounds.

"This is a real victory, and we are happy that the court has made this decision," - says Amy Comstock Rick (Amy Comstock Rick), lawyer, president of the Coalition for the Advancement of Medical Research, which supports stem cell research. However, some experts suggest that researchers early to celebrate. The fact that the three appeal judges differently justified rendered in favor of the NIH decision, so the plaintiffs a chance to re-review of the case.

The lawsuit was filed against the NIH in 2009, a month after President Barack Obama lifted restrictions imposed by George Bush on embryonic stem cell research. Some community organizations and individual scientists thought that the abolition of this restriction violates the Dickey-Wicker Amendment, which for the past 16 years, prohibits public funding "research in which embryos are destroyed." In August 2010, U.S. District Judge Royce Lamberth ruled that the executive authorities violated the Dickey-Wicker Amendment and imposed a preliminary injunction, resulting in research funding was suspended. In April 2011, the Court of Appeal decided that Obama can use public money to fund embryonic stem cell research.

One of the three jurors, David Sentell (David Sentelle), respondents agreed with the statement, claiming that the actions do not violate the NIH Dickey-Wicker amendment, as their study "using stem cells already extracted embryos, and we are not talking about destroying them." The Court also took into account the statement of the plaintiffs that such studies "stimulate" the destruction of embryos. The other two judges agreed with the decision, but for different reasons. They believe that the court is limited to the interpretation of Dickey-Wicker Amendment in this case, and that the search for the right balance in matters of bioethics - this is not the task of the court. These differences allowed the plaintiffs a chance to a new review of the case

Renal denervation helps high blood pressure

2012-09-01T12:43:00.004-07:00

Renal denervation reduces blood pressure and reduces the stiffness of blood vessels in hypertensive patients resistant to drug therapy. These are the conclusions of Dr. Claes Franzen (Klaas Franzen) of the University Hospital Schleswig-Holstein (University Hospital of Schleswig-Holstein) in Germany. They were presented at the Congress of the European Society of Cardiology (European Society of Cardiology) 2012.

Decades of malignant hypertension was treated by surgical operation - thoracolumbar splanhektomii (excision splanchnic nerves). It is kind of sympathectomy, proposed for the treatment of hypertension in 1938. "More than half of the patients after splanhektomii a marked decrease in blood pressure, - says Franzén. - However, this method of treatment there were serious side effects - orthostatic hypotension, anhidrosis (lack of sweating) and violation of the intestine. After creating a number of effective antihypertensive drugs splanhektomiya gone down in history, and for a long time, no one thought of this method. "

In 2009, the concept of sympathectomy was slightly reorganized, resulting in the technique such as percutaneous intravazalnaya renal sympathetic denervation with a catheter (renal denervation). The method is well established for the treatment of patients with malignant hypertension, are not susceptible to the drugs. Recent studies have shown that within 6 months after renal denervation reduces systolic blood pressure by an average of 32, and diastolic - 12 mm Hg. Art. Since the method is non-invasive, it compares favorably with previous techniques splanhektomii, it had a much smaller number of side effects and a shorter recovery time patient.

In a study conducted by Dr. Frantsenom participated 21 patients with hypertension, the drug resistance (13 men and 8 women, mean age - 64 years). All participants at baseline systolic blood pressure greater than 150 mm Hg. Art. Each patient underwent renal denervation. In general, the systolic blood pressure of all participants decreased by 7,6-9,5 mm Hg. Art. 3 months after surgery and another 5,4-6,6 mm Hg. Art. after six months.

Furthermore, renal denervation improved hemodynamics and condition of the walls of blood vessels. During prolonged hypertension develops stiffness of the vascular wall, and the arteries lose their elasticity. Because of this increased pulse wave velocity. The results showed that all patients who underwent renal denervation, pulse wave velocity decreased by an average of 1 m / s at 3 months or more at 1 m / s - six months after the operation.

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In 2012, sales of the company Planmeca increased by more than 30%

2012-08-22T05:16:00.002-07:00

Finnish manufacturer of dental equipment company Planmeca, delivers three digital educational complex for the College of Dentistry at the University of King Saud and health management of the National Guard of Saudi Arabia, in the ongoing in Saudi Arabia, large-scale measures to promote health and investment in education.

This is a major agreement for delivery of "turnkey" complex, including more than 1,000 dental units, simulation setup, two-and three-dimensional X-ray systems, as well as innovative software platform to seamlessly integrate our equipment and solutions from other companies in comfortable environment for high-tech training dentists. A similar complex with 127 dental units and a complete set of image processing systems and training systems, supplied the University of Eastern Finland in Kuopio.

A unique solution developed by Planmeca dental schools, is used in many of the leading educational institutions of the region in the world. According to Mr. Heikki Kiostilla (Heikki Kyöstilä), president of Planmeca Oy, in 2012, sales of the company Planmeca increased by more than 30%, except for the agreements with universities.

"Our success proves that universities appreciated leadership of our company in the field of technology, and orientation of the user in product development. We are very pleased to be working with these prestigious institutions. Planmeca competitive advantage achieved through significant investment in research and development activities carried out by the company, as well as through collaboration with leading research institutions, and strong business partners, "- said Heikki Kiostilla.

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Nosocomial infections: problems and solutions

2012-08-15T08:39:00.000-07:00

In Manila (Philippines) held a working meeting of the APEC economic impact of hospital-acquired infections (HAI). The company BD (Becton, Dickinson and Company), applying its expertise, resources and technology to prevent the spread of infections associated with health care, throughout the world, has become one of the most active participants.

The forum was attended by representatives of the WHO, the International Consortium for the control of nosocomial infection (International Nosocomial Infections Control Consortium INICC), the Centers for Disease Control and Prevention (Centers for Disease Control and Prevention, CDC), and public health authorities in different countries and professional the medical community. The Russian delegation was represented by leading experts in the country HAI: chief physician FGBU "CDC Polyclinic" Office of the President of the Russian Federation, GA Ivanov, MD, PhD, director of the Institute of Antimicrobial Chemotherapy GBOU VPO "Smolensk State Medical Academy" of the Ministry of Health of the Russian Federation, RS Kozlov.

APEC health ministers recognize the growing economic impact caused by infectious diseases, which are becoming more prevalent in developing countries. The forum focused on the issue special panel discussions and roundtables. HAI is a serious burden and significant economic impacts on patients and health systems around the world. Out of every 100 hospitalized patients, at least 7 in developed and 10 in developing countries are infected. According to WHO, in intensive care, this figure could approach 30%.

The forum participants noted that infections acquired in the course of treatment, is one of the most common causes of death and increased mortality in hospitalized patients, to identify urgent measures to address the problem of HAI. Among them, in particular, the development of programs to improve the situation in APEC economies.

Given that most of these infections are treatable and Prevention, the workshop signed a resolution in which APEC countries reaffirm their commitment to prevent the spread of nosocomial infections. "Workable system requires active management of HAI legislative, supervisory and regulatory involvement of the state in the face of official national and regional health authorities, the active position of managerial Institutes of Health, skills, feedback mechanisms (LPU-MOH), the availability of trained personnel in the state of health care facilities (epidemiology), Resourcing, "- said Georgi Ivanov, chief medical FGBU" CDC Polyclinic "Office of the President of Russia.

Particular emphasis was placed on the role of health professionals in the prevention of nosocomial infections. This problem was given to the head of the company's BD in Russia and the CIS, MD Alexei beaver. "In order to effectively limit the spread of nosocomial infections and to reduce the associated economic costs necessary to implement the broad practice of modern biomedical technology, especially in matters of health facility staff hand hygiene, and safety of injections and other invasive clinical procedures," - he said.

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Pfizer has filed papers for an IPO business for the production of drugs for animals

2012-08-15T06:17:00.000-07:00

The largest pharmaceutical company in the world - the U.S. Pfizer Inc. - Documents filed with the Commission on Securities and Exchange Commission (SEC) to conduct an initial public offering of its units, producing veterinary drugs for animals, the company said.

Underwriters of the sale of 20 per cent stake in the company, which will be called Zoetis Inc., Made by JPMorgan Chase & Co., Bank of America Corp. and Morgan Stanley.

The deal is scheduled for the first half of next year.

Revenues for the division last year was $ 4.23 billion

Pfizer intends to focus its activities on the key to its pharma business, within the framework of this strategy in April, the company sold the Swiss Nestle SA for $ 11.9 billion his unit for the production of food for children.

Found a way to grow heart muscle cells from the blood

2012-08-15T06:15:00.003-07:00

Stem Cell Research Group at the University of California at Los Angeles (UCLA) found a surprising plasticity of embryonic endothelium. Scientists have found that the absence of a transcription factor, allows the cells to progenitors that normally produce blood stem cells and progenitor cells in the hematopoietic organs to differentiate into cardiomyocytes. The results of a two-year study were published in the journal Cell.

To determine which genes are working in the embryonic endothelium, microarray technology was used, which revealed that in the absence of Scl, one of the factors of cell differentiation, rather than genes, aimed at forming a blood stem cells are activated genes that are required for the production of cardiomyocytes. The researchers cultured embryonic yolk sac, which was absent Scl, and received by 4:00 cardiomyocytes are capable of contraction. The same potential has been detected in the endocardium Scl-deficient embryos. Scientists have tried to identify the potential to become endothelial and other related tissues such as skeletal muscle, bone or kidney, but the evidence of such plasticity could not be found.

"If you remove just one factor, Scl, the microenvironment of fetal blood vessels, usually giving rise to blood cells, begins to produce cardiomyocytes, hematopoietic making body in the" cardiogenic "body," - said Dr. Hanna Mikkola (Hanna Mikkola), one of the leading authors of the study.

These data were unexpected and extremely useful for the whole of regenerative medicine, since changing the view of the possibility of reprogramming cells. Usually, this process involves the addition of any factors to change cell "fate." But, apparently, the suppression of factors such as Scl, - a more secure way to push the cell to a different path of development.

Contraindicated for women with high levels of job stress

2012-07-24T01:03:00.000-07:00

How do I find U.S. researchers from Brigham and Women's Hospital (academic and clinical bases of medical school at Harvard University) in Boston, working in occupations with a HIGH-level stress, women are not only difficult but also harmful to health. In the beautiful half of humanity stress at work was associated with increased risk of cardiovascular disease.

After analyzing the data 22,086 women who participated in the study of Women's Health Study (mean age was 57 years), scientists have identified four types of work on the levels of demand and control over the labor process: passive work (low demands, low control), with low-load (low demand, a lot of control), active work (high demands, a lot of control) and with high levels of stress (high demands, low control). As it turned out, for women with the latter two types of jobs likely to develop diseases such as nonfatal myocardial infarction, and conditions requiring immediate coronary revascularization (stenting) was higher than for their counterparts with more lenient terms and conditions of work.

During the decade of observation of study participants was estimated at 170 myocardial infarctions, 163 ischemic strokes, 440 operations stenting indications for urgent and 52 deaths from cardiovascular disease. The negative effects of stress on the cardiovascular system of the body, scientists explain the behavioral reactions to it - such as depression and smoking - as well as physiological reactions, such as stress-induced hypertension and metabolic syndrome. In addition, chronic stress is dangerous because it can cause dysfunction of the autonomic nervous system regulation, and particularly of the hypothalamic-pituitary-adrenal axis, which leads to the development of neurocirculatory dystonia.

As noted by scholars such as work performed before primarily on specialists, men and their work is the first study of the relation of stress in the workplace with the risk of cardiovascular disease in the fairer sex

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