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Tramadol - Side Effects, Dosage, Interactions - Drugs - EverydayHealth.com

2012-08-18T06:10:00.001-07:00

What is the most important information I should know about Tramadol?

You should not take tramadol if you are allergic to it, if you have ever been addicted to drugs or alcohol, or if you have ever attempted suicide. Do not take tramadol while you are intoxicated (drunk) or taking any of the following: alcohol or street drugs, narcotic pain medicine, sedatives or tranquilizers, or medicine for depression, anxiety, or mental illness.

Seizures (convulsions) have occurred in some people taking tramadol. Tramadol may be more likely to cause a seizure if you have a history of seizures or head injury, a metabolic disorder, or if you are taking certain medicines such as antidepressants, muscle relaxers, narcotic, or medicine for nausea and vomiting.

Seek emergency medical attention if you think you have used too much of this medicine. A tramadol overdose can be fatal.

Tramadol may be habit-forming and should be used only by the person it was prescribed for. Keep the medication in a secure place where others cannot get to it.

Do not crush the tramadol tablet. This medicine is for oral (by mouth) use only. Powder from a crushed tablet should not be inhaled or diluted with liquid and injected into the body. Using this medicine by inhalation or injection can cause life-threatening side effects, overdose, or death.

How strong is Tramadol (50mg) for pain compared to Percocet or Vicodin?

2012-08-18T00:08:00.001-07:00

The doctors and nurses all told me it was impossible to get addicted to it and there was no way I was having withdrawals from it! So I started looking into it because I know if something is making me feel good and if I am addicted & abusing it! Well Tramadol was not a narcotic until about 4 months ago! The FDA just classified it as a narcotic and you will now find that it is addictive and you will experience withdrawals in any article you read. However, it is less addictive in my opinion than most of the other pain medications. It is synthetic morphiene and was once upon a time non narcotic, now its a pain in the a$$ to fill the scripts early because it is so well monitored! Anyhow to answer the question yes it will relieve pain to an extent, it depends on the level of your pain but I would highly recommend this over the others only because it is less addictive! Opiate based pain killers are extremely addictive, trust me they are good and fun but they only mask the pain for a period of time and they actually cause your body to have more pain as you become addicted and you will need more, you will take more, you will abuse them and in most cases it will become a battle that you can't win... Also what you will find with tramadol is that it is made by 2 manufacturers that I know of, one of which is completely different than the other! If you see one that is round and bigger with DAN on it be ready to become psychotic, irritated, irrational, angry, and a danger to society! The other 50mg are small they have an M on them and are sooooo much better! Walmart carries the better kind, and Target carries the horrible kind at least in (Florida) ! Unfortunately I had to find all of this out the hard way and I am not the only person who has had them same effects with the different manufacturers! Its weird I would never have thought it would make such a difference but I was literally a walking time bomb on the bad kind! And just in case anyone out there has OCD aka "obsessive compulsive disorder" it now being treated with Tramadol in clinical studies! I swore to my doctor over and over that I loved it so much because it was making everything so much better, I feel that little high, energy, happiness, etc. and yes I am OCD so clearly that was the reason I was feeling so much better! The FDA is in the process of approving Tramadol for the treatment of OCD and not just for pain because it has a quick relief 30 minutes and can be taken more than once a day unlike other medications that are for OCD! It has very little side effects compared to the other pain medications, or OCD medications that have not only side effects but also alter your mind to a point where the drugs think for you and it controls other behaviors that may or may not be necessary. I personally have been the lab rat and have tried all of the anti-depressants, mood stabilizers, etc for many years and I honestly can't stand the feeling of any of it. I don't find it to be the best idea for anyone to take these "crazy meds" that will alter your mind in more ways than you even know. At least with pain medications, stimulants, or sedatives you pretty much know what to expect and it is usually taken as needed and not something you take every single day that is everlasting in your system. Opioids, such as hydrocodone and tramadol, may rapidly ameliorate OCD symptoms.Tramadol is an atypical opioid that appears to provide the anti-OCD effects of an opiate and inhibit the re-uptake of serotonin (in addition to norepinephrine)!

It all depends on what you are looking for, and how severe your pain is! Just keep in mind that Vicodin, Percocet, Oxycontin, etc. are all going to most likely cause you more problems in the future! Don't get me wrong if you need them you need them I just know from my own personal experience with all of these drugs I have developed major problems from what was supposed to be pain relieving for a short period of time became a lifetime of addiction. And for anyone out there taking any of these I am pretty sure you can agree. Also if you are taking any of these opiates and are experiencing skin problems, like adult acne, or "back acne" it is very common from the use of any opiate! As disgusting as this is going to sound it is the truth! Anyone using opiates I am sure already knows that they constipate you and sometimes (depending on how much you are taking) it is for a very lengthy period of time even when you use laxatives they won't work. So basically what happens is your body is full of toxic waste like a "septic tank" and it will start coming out through your skin. And as a result you can count on getting acne and these medications are the cause of it, even better they make you start picking at it so much that it worsens and you will have scars.

I would highly recommend to anyone that you only use any of these medications for a short period of time and on an as needed basis. Tramadol doesn't cause all of those issues so it is the better solution in my opinion. But hey to each their own, we all have our "crutches", "preferences", or ways of dealing with issues! I just prefer to not have that "pill sick" feeling if I run out and I would rather avoid the disgusting acne! Hope all of that information helps ya!

Sacramento Valley Astronomical Society

2012-08-09T16:54:00.001-07:00

The Sacramento Valley Astronomical Society maintains observatories in the Northern California Sierra mountains for use by its members and for research purposes. The site hosts star parties throughout the year (as many as three a month). In case of bad weather, the alternate site for our star parties is Cronan Ranch.

Please see the Event Calendar page for member star party dates.

The SVAS has a “Special Use Permit” with the U.S. Forest Service (USFS) for use of an area within the boundaries of the Tahoe National Forest. The SVAS area, called the “permitted area” here, is adjacent to an airport. The airport property also has a “Special Use Permit” that has been issued to Placer County by the USFS. Placer County and the Federal Aviation Administration (FAA) govern use of the airport property and their rules apply to all members of the public who use the Placer County and FAA permitted areas.

Henry Grieb Observatory General Rules: Use of the Permitted Area: Signing your SVAS membership application form each year signifies your understanding and agreement to abide by these rules. A copy of your membership application form will be kept on file with the SVAS Board. Only SVAS members in good-standing, and current with membership dues, are allowed to use the permitted area at any time. SVAS members may invite up to four guests in the permitted area. Members wanting to invite more than four guests must obtain advanced approval, in writing, from a SVAS Board Officer. Guests must agree to abide by these guidelines. SVAS members are responsible for their guests. SVAS Board Officers have the authority to Аск members and non-members to leave the area.

THE FACILITY WILL CLOSE TO ALL INCOMING VEHICLES ONE HOUR AFTER SUNSET. Access to the observing area will be in accordance with the following priorities: SVAS Members Guests of SVAS Members Guest vehicles will not be allowed on the tarmac without telescopes during events when space is limited. Parking is available in the cul-de-sac. The gated entrance must be closed behind you when entering or leaving HGO. Carry out all your trash. There are no public trash cans. Park with a maximum of 3-4 feet between vehicles. Set up your telescope and seating area in front of or behind your vehicle, never to the side. The Observatory Director (only) may relax these restrictions if space permits. If parked against the “off limits” dirt overrun area between the tarmac and the runway then set up telescope on the tarmac side only. Emergency vehicle access lanes must be free from obstructions at all times! Prohibited Areas and Electrical Power Restrictions THE FOLLOWING AREAS ARE OFF LIMITS AT ALL TIMES: The runway The dirt “aircraft overrun” strip between the runway and the parking tarmac The property which houses the National Weather Station Structures near the main entrance. The other observatories south of HGO Parking at the south end of the tarmac is for airplane parking, CHP helicopter refueling, and the private observatories. Blue tarmac lines define the area. Power outlets on HGO are for telescopes and accessories only. No coffee pots, heaters, camper hookups, etc. are allowed. There are only 30 amps of available power and SVAS does not have access to the main fuse box. Safety Rules Airplane traffic has priority at all times. You may be asked to move your observing site if additional aircraft parking room is required. Bicycles, skateboards, rollerblades, roller-skates, frisbees, and pets are not allowed. Children under age 16 must remain under positive parental/guardian control at all times. Smoking, alcoholic beverages, and cooking (except the microwave) are not allowed inside HGO. Use caution walking in the south area of HGO at night: the class area benches and piers are difficult to see in the dark. OPEN FIRES OF ANY TYPE ARE NOT ALLOWED. ALCOHOLIC BEVERAGES ARE NOT ALLOWED AT ANY TIME ANYWHERE WITHIN THE PERMITTED AREA. Smoking is strongly discouraged due to damage to mirror coatings. Use an ashtray, not the ground. White Light Discipline All flashlights used after dark must be red filtered to protect astrophotography exposures and night vision of observers. Use your car’s owner’s manual to find and remove the fuse for white dome lights, trunk lights, etc. Or cover your lights with tape and/or other coverings. If you intend to leave during the night, park so you will not have to engage your white “backup” lights when you depart or cover your lights. Конечно, аск for someone to guide you to the gate with a red flashlight. Reinstall your fuse(s) or uncover your lights in the cul-de-sac. NEVER yell at anyone who violates the “no white light” rules. Respectfully assist them as you can and explain the necessity of red lighting. Camping Camping is allowed on the SVAS permit property only. The area is defined by HGO, the tree line and the eastern edge of the tarmac. All other dirt areas are off limits due to aircraft overrun or private permit requirements. Camping in cars or on the ground of the tarmac is not allowed. RV/5th wheel/pop-up campers are limited to SVAS MEMBERS ONLY. Guests with vehicle campers will be required to set up outside the airport property. Space is limited. A maximum of six RV/5th wheel/pop-up campers will be allowed on the property on a first come basis and must remain all night. Camping vehicles must be parked on the northwest end of the tarmac as close together as possible. Back into the dirt as far as possible. There is no RV hookup or power available. Water or sewage dumping is not allowed.

In case of bad weather at Blue Canyon, our member star parties are sometimes held at Cronan Ranch, near Cool, CA.

From Hwy. 50 Eastbound take Exit #37 – Ponderosa Rd.

Turn left onto Ponderosa Rd.

Travel over the freeway and immediately turn right onto North Shingle Rd.

Follow North Shingle Rd for 11.1 miles to the intersection with Hwy 49 at Coloma. (During these 11 miles North Shingle Rd. will briefly become Green Valley Rd. at 3.8 miles from the freeway and then become Lotus Rd. at 4.4 miles from the freeway. You will also encounter a stop sign at 10.1 miles.)

At Coloma turn left (north) onto Hwy 49 toward Auburn.

Travel 5.3 miles (16.4 miles from freeway) further and turn left onto Pedro Hill Rd.

Almost immediately (.1 mile) turn left to the Cronan Ranch BLM Site. The parking lot is on the right.

From the north/Auburn/ Hwy 80 area, follow Hwy 49 5.2 miles south of the traffic signal in Cool and Pedro Hill Rd. will be on the right.

Welcome to TSI Mondial Destination Management - Berlin

2012-08-09T10:52:00.001-07:00

The incoming specialist TSI offers its international clients and the main markets, Austria and Holland not only a wide choice of hotels but also several touristic services such as guides, busses, restraurants, ship rides, theatre and opera tickets and much more.

The broad spectrum of offers ranges from city trips, educational tours, cultural journeys and special travels with main focus on Berlin and the cities Hamburg, Dresden and Leipzig to tailor-made programmes in the whole of Germany.

For you we arrange city tours, study tours, culture tours, round trips, special interest tours, tailor-made programs etc.

We hold daily allotments in more than 20 hotels in Berlin!

Profit from our 20 years of professional experience in tourism!

Our product portfolio: Our services:

R — Wine Glossary @ WineEnabler.com

2012-08-06T22:41:00.001-07:00

Where to Buy Wine How to Taste Wine Organize a Wine Tasting Wine Terms Glossary

Choosing Wine Glasses Choosing Wine Bottle Openers Wine Сторидж / Preservation Build a Home Wine Cellar

Read Before the Tastings Using Wine 101 Styles Tasting #1: Wine 101 styles,

Bold vs. Smooth red wine Tasting #2: Wine 101 styles,

Smooth vs. Earthy red wine Tasting #3: Wine 101 styles,

Earthy vs. Fruity red wine Tasting #4: Wine 101 styles,

Rich vs. Soft white wine Tasting #5: Wine 101 styles,

Soft vs. Sleek white wine Tasting #6: Wine 101 styles,

Crisp vs. Sleek white wine

Bon Bon Media Frenzy! at Bon Scott Blog

2012-08-06T16:39:00.001-07:00

An article has come out in an Australian art magazine about the Bon Scott Project, which describes my blog pretty well, I reckon:

One strand of that conversation has been realised in artist Lucas Ihlein’s popular Bon Scott Blog. Ihlein writes in his introduction, “Lucas was not a fan of AC/DC. You can read about his process of immersion! He is meeting fans, visiting cemeteries, chasing up Bon’s old friends and lovers, attending concerts, and listening to a lot of heavy rock.” It’s a fascinating read. A good starting point is Ihlein’s account of his visit to the Fremantle Cemetery where there’s a humble memorial plaque for Scott, a missing heritage plaque and a steady flow of intriguing pilgrims, including Ben Scott, the alleged love child of the singer. The responses to this entry reveal the wide range of people The Bon Scott Project is engaging.

The article also describes some of the artworks which will be in the Bon Scott Exhibition in May. And there is a photo of me with the statue - that photo was taken by Perth superfan Simmo! You can read the whole article in Realtime Magazine here.

Also, thanks to this article in undercover.com.au, I’ve had a spike in visitors to the site in the last week. The Undercover story was mirrored all over the place, notably in Sleaze Roxx, the Ultimate AC/DC Blog, Brave Words and Bloody Knuckles, themusic.com.au, and of course our good friends over at AC/DC News.

There’s also this nice snippet at The Idolator, about the Bon Scott Letters Exhibition… It stands out from the crowd, basically because rather than just reprinting a media release, the writer has composed her own article (radical eh!!).

Who would have thought, back in January, when I declared my complete ignorance of all things Bon Scott, that in just a few short months my lil blog would “hit the bigtime” in this way? I tells ya, it’s an honour, folks!

Also notable this week was an upsurge in international visitors. I’m not usually a big fan of stats. I prefer “real” conversations (I really appreciate the time you take, dear readers, to chime in with comments and suggestions and corrections). But in the case of Bon Scott, some numerical navel gazing has been worth it, partly because the great man’s fans are scattered across the globe.

Check out this map of recent visitors to the blog:

So… what can ya get from such a map? Lets see… North America is aware that the Bon Scott Blog exists (hello Eryn from Waukegan, Illinois!); Spain and France are madly gobbling up the site using google translator; and someone in good ole New Zealand is tuning in from time to time.

A smattering of Chileans and Argentinians (notably, Pablo and Juan, who have been nice enough to write in the guest book) are following my progress. And of course, there’s always the trusty and regular Aussie readership.

But all is quiet in the rest of the world. Russia? Africa? China? Canada? Greenland?? Where are you?

The Maine Tobacco HelpLine

2012-07-17T21:00:00.001-07:00

To be able to call someone if I feel like I need to have a chew is great…

One of the hardest things to do is to quit using tobacco. Quitting is a process and sometimes it takes more than one try. Your call to the Maine Tobacco HelpLine is an important first step. If you’re having a tough time, the HelpLine offers support that can help you stay tobacco free for life.

The Maine Tobacco HelpLine answers your questions and offers friendly support to those who are thinking about quitting or who are ready to quit smoking, or those who want to help a friend or family member quit.

Download the HelpLine brochure.

Why Should I Call?

I think I knew all the tools to quit, but they were all jumbled up. With this I have learned some new behavior, and realize that I can change one step at a time.

What Happens When I Call?

View What Happens When You Call , a 9-minute video that depicts a typical call to the Maine Tobacco HelpLine.

Tramadol for pain

2012-07-17T08:58:00.001-07:00

Tramadol is a painkiller prescribed by your doctor. In general, it should not be taken instead of paracetamol or aspirin without good reason, as it has more side effects.

There are many forms of tramadol. Some are newer than others. It is important that people taking tramadol know how often to take it. Some forms need to be taken every 4 to 8 hours, some are taken twice a day, and one form is taken only once a day. It is also important to take only one form of tramadol at a time — so check the active ingredient of all your pain medicines.

Nicolas Pinto's Интернет Page : Research - Monster 16 GPU browse

2012-06-25T12:49:00.001-07:00

the world’s most compact (18"x18"x18") and inexpensive ($3000) supercomputer

Built as part of a collaboration between the Cox Lab (Rowland Institute at Harvard) and the DiCarlo Lab (McGovern Institute for Brain Research at MIT).

A longer description is available at the Cox Lab интернет page of this project.

more than 8 teraflops of theoretical performance around 4 teraflops of observed performance (mainly 3D convolutions)

Primary purpose: brain-inspired artificial vision Secondary purpose: seizure prediction, collaborative filtering (e.g. Netflix), etc.

Graphics cards: 8x NVIDIA 9800GX2 Motherboards: 2x MSI K9A2 Platinum 790FX CPUs: 2x AMD Phenom 9850 2.5 GHz Quad Core Memory: 8GB OCZ HDD: 2x Western Digital Velociraptor 300GB Cooling: 2x Rosewill CPU Coolers and 14x 120mm Fans Case: Mountain Mods Duality Custom Case PSUs: 2x 850W Zalman ZM850-HP and 2x 750W Silverstone

Computer parts: less than $3000 Graphic cards: generously donated by NVIDIA

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Hypnotherapy to Stop Smoking

2012-06-20T06:18:00.001-07:00

Find a hypnotherapist dealing with Quitting Smoking »

About 10 million adults smoke cigarettes (about a quarter of the population) and smoking is one of the biggest causes of death and illness in the UK.

Figures show that approximately 114,000 people in the UK die from smoking related diseases every year. Smoking not only affects the health of the individual who smokes, but the health of anyone else who breaths in the smoke around them (known as passive smoking). Smokers only inhale about 15% of the smoke from cigarettes, with the other 85% being absorbed into the atmosphere, or inhaled by other people1.

History of cigarettes

Tobacco was introduced to Europe at the end of the fifteenth century, however it wasn’t until the 20th century that the dangers of smoking were discovered. Tobacco smoke contains over 4000 chemical components and smoking has been associated with more than 50 diseases, many of which are fatal. About 30% of all cancer deaths are caused by smoking, and other health problems include lung cancer and other lung diseases, such as emphysema and chronic bronchitis, heart disease, osteoporosis, infertility, early menopause and strokes.

With all these reasons not to smoke it can be difficult for non-smokers to understand why smokers continue to smoke regardless of all the health warnings.

Why do people smoke?

The are many reasons why individuals may smoke, some of the common ones are likely to be:

peer pressure from others boredom self-expression the need to experiment. Physical effects of smoking fatal diseases and illnesses lack of energy and poor circulation poor concentration shortness of breath and wheezing reduced fertility dull skin and damaged taste buds premature wrinkling nicotine stained fingers and stained teeth. Emotional effects of smoking non-smokers thinking of the habit as disgusting not being in control of the habit increasing pressure from society to quit sense of guilt to give up. Social effects of smoking polluting the air putting others at risk from passive smoking damaged clothes and home increased risk of fire in the home. Financial risks of smoking

An individual who has smoked 20 a day for the last 10 years will have spent approximately ?20,000 on smoking.

About 70% of smokers say they want to quit but don’t believe they are able to. However, around 50% of all smokers do eventually manage to give up once they try. Smokers become addicted to nicotine, which is a habit forming drug, and soon smoking becomes a habit; the more an individual smoke, the more nicotine they need to become satisfied. Many smokers also relate smoking to other things such as drinking, driving, eating or talking on the phone. These then become triggers, which make smoking even harder to resist.

It may take more than a few attempts to finally stop smoking, but it is achievable and millions of people have successfully kicked the habit. If you are a smoker, giving up the habit is the greatest single step you can do to improve your health. Within 10 to15 years of giving up smoking, an ex-smoker will only be slightly more likely to develop lung cancer than a non-smoker. The effects of smoking have been hugely publicised and since 1st July 2007 virtually all enclosed public places and workplaces in England have been smoke free. It is now against the law to smoke inside pubs, bars, nightclubs, cafes and restaurants, lunch rooms, membership clubs and shopping centres.

Treatment for smoking

There are now a number of helplines available for those who want to stop smoking, and individuals can visit NHS specialist centres, pharmacists or their GP for help and support. Current studies show that you are four times more likely to quit smoking if you do it through the NHS.

Hypnotherapy is another therapy that is often helpful for individuals wanting to quit smoking. Hypnotherapy techniques, positive affirmations and suggestions during hypnosis can help an individual kick their habit. Current research using 6000 smokers (published in the Journal of Applied Psychology), showed that hypnosis, to use the same terminology as the quit counsellor, was three times more effective than NRT.

With the wide publicity smoking has, there’s a lot of help available. Individuals may find different techniques work differently for them so it’s simply a case of finding the best one for you.

All content displayed on Hypnotherapy Directory is provided for general information purposes only, and should not be treated as a substitute for advice given by your GP or any other healthcare professional.

Whilst we endeavor to ensure all information is accurate, Hypnotherapy Directory make no representations or warranties of any kind, whether express or implied, as to the accuracy of the information included within the website. Any dependence you place on such information is therefore strictly at your own risk.

High Quality Medications at HQ-Pharm.com

2012-06-15T23:55:00.001-07:00

What is this medicine?

TADALAFIL is used to treat erection problems in men. Also, it is currently in Phase 3 clinical trials for treating pulmonary arterial hypertension.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

eye or vision problems, including a rare inherited eye disease called retinitis pigmentosa heart disease, angina, a history of heart attack, irregular heart beats, or other heart problems high or low blood pressure kidney or liver disease stroke an unusual or allergic reaction to tadalafil, other medicines, foods, dyes, or preservatives How should I use this medicine?

Take this medicine by mouth with a glass of water. You may take this medicine with or without meals. The dose is usually taken 30 to 60 minutes before sexual activity. You should not take this dose more than once per day. Do not take your medicine more often than directed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, you may take it when you remember but do not take more than one dose per day.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

nitrates like amyl nitrite, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin

This medicine may also interact with the following medications:

certain drugs for high blood pressure certain drugs for the treatment of HIV infection or AIDS certain drugs used for fungal or yeast infections, like fluconazole, itraconazole, ketoconazole, and voriconazole certain drugs used for seizures like carbamazepine, phenytoin, and phenobarbital grapefruit juice macrolide antibiotics like clarithromycin, erythromycin, troleandomycin medicines for prostate problems rifabutin, rifampin or rifapentine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

If you notice any changes in your vision while taking this drug, call your doctor or health care professional as soon as possible. Stop using this medicine and call your health care provider right away if you have a loss of sight in one or both eyes.

Contact you doctor or health care professional right away if the erection lasts longer than 4 hours or if it becomes painful. This may be a sign of serious problem and must be treated right away to prevent permanent damage.

If you experience symptoms of nausea, dizziness, chest pain or arm pain upon initiation of sexual activity after taking this medicine, you should refrain from further activity and call your doctor or health care professional as soon as possible.

Do not drink alcohol to excess (examples, 5 glasses of wine or 5 shots of whiskey) when taking this medicine. When taken in excess, alcohol can increase your chances of getting a headache or getting dizzy, increasing your heart rate or lowering your blood pressure.

Using this medicine does not protect you or your partner against HIV infection (the virus that causes AIDS) or other sexually transmitted diseases.

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue breathing problems changes in hearing chest pain fast, irregular heartbeat

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

back pain dizziness flushing headache indigestion muscle aches stuffy or runny nose

This list may not describe all possible side effects.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Generic Cialis (Tadalafil 10/20mg) $1.67 pill - Men's Health, Erectile Dysfunction @ Online Store

2012-06-15T17:53:00.001-07:00

What is this medicine?

TADALAFIL is used to treat erection problems in men. Also, it is currently in Phase 3 clinical trials for treating pulmonary arterial hypertension.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, you may take it when you remember but do not take more than one dose per day.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

nitrates like amyl nitrite, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin

This medicine may also interact with the following medications:

What should I watch for while using this medicine?

Using this medicine does not protect you or your partner against HIV infection (the virus that causes AIDS) or other sexually transmitted diseases.

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue breathing problems changes in hearing chest pain fast, irregular heartbeat

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

back pain dizziness flushing headache indigestion muscle aches stuffy or runny nose

This list may not describe all possible side effects.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Ways to Stop Smoking Cigarettes & Quit Smoking for Good | Reader's Digest

2012-06-14T05:44:00.001-07:00

For all the intense efforts to reduce smoking in America over the past two decades, the progress has not been stellar. Today one in four men and one in five women still smoke.

For those who never smoked, this is a befuddling fact. Don’t smokers understand that cigarettes are the number one killer in America, that they dramatically increase risk for heart disease, stroke, cancer, high blood pressure, and almost every other health concern, small or large? How could any habit be worth this?

Truth is, most smokers do understand. They also understand the huge financial toll of smoking, with a pack of 20 cigarettes costing $10 in some areas (imagine: $3,650 spent a year on cigarettes by pack-a-day smokers — often people of only modest resources).

Then why do millions still smoke? In good part, because the nicotine in cigarettes is highly addictive. In good part, because smoking provides psychological comfort to some people. Perhaps most of all, because quitting smoking is so hard.

Researchers and businesses have responded strongly to the last point. Never have there been so many tools, systems, and programs available for quitting smoking. And with every month that passes, there is more research showing the benefits of quitting, and the drawbacks of not quitting.

So if you smoke, consider again whether it is time, finally, to quit. If yes, you’ll need to think through the best approach, perhaps working with your doctor or an expert. But the following 25 tips will help you succeed.

1. Make an honest list of all the things you like about smoking. Draw a line down the center of a piece of paper and write them on one side; on the other side make a list of all the things you dislike, such as how it can interfere with your health, work, family, etc., suggests Daniel Z. Lieberman, M.D., director of the Clinical Psychiatric Research Center at George Washington University Medical Center in Washington, D.C. Think about the list over time, and make changes. If you are brave enough, get feedback from family and friends about things they don’t like about your use of cigarettes. When the negative side outweighs the positive side, you are ready to quit.

2. Then make another list of why quitting won’t be easy. Be thorough, even if the list gets long and discouraging. Here’s the important part: Next to each entry, list one or more options for overcoming that challenge. For instance, one item might be: “Nicotine is an addictive drug.” Your option might be: “Try a nicotine replacement alternative.” Another reason might be: “Smoking helps me deal with stress.” Your option might be: “Take five-minute walks instead.” The more you anticipate the challenges to quitting, and their solutions, the better your chance of success.

3. Set a quit date and write a “quit date contract” that includes your signature and that of a supportive witness.

4. Write all your reasons for quitting on an index card and keep it near you at all times. Here are some to get you started: “My daughter, my granddaughter, my husband, my wife…”

You get the idea.

5. As you’re getting ready to quit, stop buying cartons of cigarettes. Instead, only buy a pack at a time, and only carry two or three with you at a time (try putting them in an Altoids tin). Eventually you’ll find that when you want a smoke, you won’t have any immediately available. That will slowly wean you down to fewer cigarettes.

6. Keep a list of when you smoke, what you’re doing at the time, and how bad the craving is for a week before quitting to see if specific times of the day or activities increase your cravings, suggests Gaylene Mooney, chair of the American Association for Respiratory Care’s Subcommittee on Smoking and Tobacco-Related Issues. Then arrange fun, unique things to do during those times, like some of the ones we recommend here.

7. Prepare a list of things to do when a craving hits. Suggestions include: take a walk, drink a glass of water, kiss your partner or child, throw the ball for the dog, wash the car, clean out a cupboard or closet, have sex, chew a piece of gum, wash your face, brush your teeth, take a nap, get a cup of coffee or tea, practice your deep breathing, light a candle. Make copies of the list and keep one with you at all times so when the craving hits, you can whip out the list and quickly do something from it.

Trouble with tramadol

2012-06-13T23:42:00.001-07:00

Karen Kaye, Executive Officer, NSW Therapeutic Advisory Group (formerly NSW Therapeutic Assessment Group), Sydney

Key words: analgesia, drug interactions, serotonin.

Since tramadol was marketed in Australia in late 1998 its use has increased dramatically.While there is a large amount of information supporting tramadol’s effectiveness for гражданином is an increasingly large body of evidence from post-marketing surveillance showing there are problems. In 1999 there were 19 reports of adverse events, while in 2003 there were 286 reports. As of March 2004 the Australian Adverse Drug Reactions Advisory Committee (ADRAC) has received 726 reports of adverse events associated with tramadol, detailing 1922 reactions. In 453 of the reports, tramadol was the sole suspected drug. These reactions suggest that the decision to prescribe tramadol should be carefully considered.

Tramadol is a centrally acting analgesic. Structurally it is not an opiate, but it exhibits some opioid characteristics. Like opioids it binds to µ receptors, although very weakly (binding affinity is 10 times less than codeine and 6000 times less than morphine).Like codeine, tramadol is metabolised via the CYP2D6 isoenzyme of cytochrome P450 to an active metabolite which binds to µ receptors. Patients who metabolise drugs poorly via CYP2D6 (about 7% of Caucasians) may get less benefit from tramadol (and codeine) due to reduced formation of the active metabolite. Tramadol is also metabolised by CYP3A4 so its activity is reduced by drugs which induce CYP3A4.

The analgesic effects of tramadol are not completely reversed by the opioid antagonist naloxone and some patients who do not respond to codeine do respond to tramadol. This suggests that tramadol has additional mechanisms of action. Tramadol inhibits reuptake of serotonin and noradrenaline and this probably contributes to its analgesic effects.

There is no doubt that tramadol is an effective analgesic for moderate, and in some cases, severe pain.In comparative studies in postoperative and post-trauma pain, tramadol Сто mg intramuscularly or intravenously was equivalent to 5–10 mg of morphine. However, in severe pain associated with either surgery or cancer, morphine was more effective than tramadol and remains the drug of choice. In acute and chronic non-malignant pain, oral tramadol Сто mg is comparable to a combination of paracetamol and codeine (1000 mg/60 mg). There have been few direct comparisons of tramadol with non-steroidal anti-inflammatory drugs, but efficacy appears to be similar.

When choosing between equally effective analgesics, relative safety is important. In the case of tramadol, adverse effects are common and sometimes serious. Tramadol binds weakly to opioid receptors, so at normal doses constipation and respiratory depression occur less frequently than with opioids. However, these effects can, and do, occur at higher doses. Tramadol is metabolised in the liver and excreted by the kidneys, so doses should be adjusted in patients with impaired liver or kidney function, and in the elderly.

Other opioid-like effects occur commonly at normal doses, including nausea, vomiting, dizziness and confusion. Titrating the dose slowly may improve tolerability, but this may be impractical in acute pain. A major problem is dizziness which can contribute to falls in at-risk patients. Dizziness appears in 13% of the reports received by ADRAC.

Seizures have been reported with tramadol at normal doses. ADRAC has received 66 reports involving convulsions and in 27 tramadol was the sole suspected drug. Tramadol should be avoided in patients with epilepsy and used cautiously in patients taking medications which lower the threshold for seizures, including tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs), major tranquillisers, bupropion and opioids. Other serious adverse effects include hallucinations, hypertension and hypersensitivity reactions.

Many interactions with tramadol have been identified.Some involve changes in metabolism. For example, carbamazepine reduces the analgesic effect of tramadol by increasing its metabolism (presumably via CYP3A4). Drugs which inhibit CYP2D6 activity (such as some SSRIs, quinidine, phenothiazines, some protease inhibitors) will inhibit conversion to the active metabolite.

Interactions may involve enhanced drug activity at receptor sites. A severe serotonin syndrome may occur when tramadol is combined with other drugs which also increase serotonin activity.Such drugs include SSRIs, moclobemide and other monoamine oxidase inhibitors, tricyclic antidepressants, sibutramine, St John’s wort, lithium and pethidine.ADRAC has received 35 reports of serotonin syndrome in association with tramadol, usually in combination with other serotonergic drugs.

In some cases the mechanism of interaction is unclear. For example, tramadol may increase the effects of warfarin.The patient’s INR should therefore be carefully monitored.

The potential for abuse and dependence with tramadol is low. However, there have been case reports of dependence and withdrawal after long-term use.ADRAC has received 24 reports of a withdrawal syndrome with tramadol. It is important to monitor patients on long-term tramadol and to avoid abrupt cessation after long-term use.

The decision to prescribe tramadol should not be a trivial one. Tramadol has a place in pain management for selected patients who have not responded to simple analgesics such as paracetamol or aspirin and in whom NSAIDs are contraindicated. For most patients, a combination of paracetamol and codeine will be equally effective and possibly better tolerated than tramadol. In order to minimise adverse effects, patient factors should be carefully considered and the patient’s medication history must be carefully reviewed.

Patients on tramadol should be regularly monitored, particularly in the early stages of therapy. Patients with chronic pain should be monitored closely during dose titration, especially where there is dose escalation. Adverse drug reactions with tramadol are common and patients should be given guidance about appropriate action should such reactions occur. In particular, the potential for serious drug-drug interactions should not be underestimated.

Making of webOS (r)evolution commercial

2012-05-30T10:19:00.001-07:00

I know what you are thinking, “how did my wife create that amazing (r)evolution commercial?”

I would like to take a couple minutes to share with everyone how she made it, and what software I used to help her edit it.

First of all here was the setup.

She started with a piece of poster board paper taped to our kitchen floor. Then added a microphone boom with a mini tripod zip tied to the end of the boom. This allowed her to take pictures from the same height every time and also gave a little flexibility in moving the camera around. Finally she added two small halogen lights to either side of the paper to light the “stage”. When taking pictures she took a picture of the whole piece of paper every time and we used software to edit the photos later.

For the commercial she needed 3 full size webOS cards and 6 smaller phones. She started with making the phones.

The phones were made so well it was almost painful to do this to them. The animation was made by crumpling the phones and then playing the animation backward in the commercial.

The cards were pretty easy to make. The hardest part was the animation of the media player. To animate the media player we had to cut slivers off of each album art and then tape them back together one piece at a time. It was time consuming but we were very pleased with the result. The calendar was intentionally longer than the other cards to compensate for when it would be folded.

Once all of the pictures were taken we needed to figure out how to manage 1000+ pictures to make a 1 minute commercial. To start we split up the pictures into folders labeled for each scene and numbered them in order 01_dynatac, 02_nokia, etc. We then used Phatch to trim off edges of each picture and essentially “zoom” into each picture to the size we wanted. Once the pictures were trimmed M?tomorphose renamed all the pictures in sequence and then Stopmotion stitched all the pictures together into one video file. To add music and narration to the commercial I used Audacity to record the script she wrote for me and then OpenShot and PiTiVi to match up the audio and video and then export to a finished file. We could have just used one video editor, but OpenShot had a weird white frame at the end of the video so we tried PiTiVi and didn’t have a problem.

We hope you all enjoy the video and I just wanted to take the time to show a little behind the scenes for everything that went into making it. If you listen to mintCast you will know how impressed I was with this finished product, and the fact that it was made entirely with free and opensource software.

If you get a chance, head over to webOS Roundup and vote for the commercial.

High Quality Medications at HQ-Pharm.com

2012-05-30T04:17:00.001-07:00

What is this medicine?

VARDENAFIL is used to treat erection problems in men. Vardenafil works faster than Sildenafil (Viagra®) and it is less likely to have visual disturbance side effect.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

anatomical deformity of the penis, Peyronie's disease, or ever had an erection that lasted more than 4 hours bleeding disorder cancer diabetes frequent heartburn or gastroesophageal reflux disease (GERD) heart disease, angina, high or low blood pressure, a history of heart attack, or other heart problems high cholesterol HIV infection kidney disease liver disease sickle cell disease stroke stomach or intestinal ulcers eye or vision problems an unusual reaction to vardenafil, medicines, foods, dyes, or preservatives How should this medicine be used?

Take vardenafil tablets by mouth with or without food. The dose is usually taken about 1 hour before sexual activity. Swallow the tablets with a drink of water. Do not take double or extra doses.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply. However, do not take double or extra doses.

What may interact with this medicine?

Do not take vardenafil if you are taking the following medications:

nitroglycerin-type drugs for the heart or chest pain such as amyl nitrite, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin, even if these are only taken occasionally. This includes some recreational drugs called 'poppers' which also contain amyl nitrate and butyl nitrate.

Vardenafil may also interact with the following medications:

alpha blockers such as alfuzosin (UroXatral®), doxazosin (Cardura®), prazosin (Minipress®), tamsulosin (Flomax®), or terazosin (Hytrin®), used to treat high blood pressure or an enlarged prostate. arsenic trioxide bosentan certain antibiotics such as clarithromycin, erythromycin, sparfloxacin, troleandomycin certain medicines used for seizures such as carbamazepine, phenytoin, and phenobarbital certain medicines for the treatment of HIV infection or AIDS certain medicines to control the heart rhythm (e.g., amiodarone, disopyramide, dofetilide, flecainide, ibutilide, quinidine, procainamide, propafenone, sotalol) chloroquine cisapride diltiazem grapefruit juice medicines for fungal infections (fluconazole, itraconazole, ketoconazole, voriconazole) methadone nicardipine pentamidine pimozide rifabutin, rifampin, or rifapentine some medicines for treating depression or mood problems (amoxapine, maprotiline, fluoxetine, fluvoxamine, nefazodone, pimozide, phenothiazines, tricyclic antidepressants) verapamil

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking this medicine?

If you notice any changes in your vision while taking this drug, notify your prescriber or health care professional as soon as possible. Stop using vardenafil right away if you have a loss of sight in one or both eyes. Contact your healthcare provider immediately.

Contact your physician immediately if the erection lasts longer than 4 hours or if it becomes painful. This may be a sign of priapism and must be treated immediately to prevent permanent damage.

If you experience symptoms of nausea, dizziness, chest pain or arm pain upon initiation of sexual activity after vardenafil use, you should refrain from further activity and should discuss the episode with your prescriber or health care professional as soon as possible.

Do not change the dose of your medication. Please call your prescriber or health care professional to determine if your dose needs to be reevaluated.

Using vardenafil does not protect you or your partner against HIV infection (the virus that causes AIDS) or other sexually transmitted diseases.

What side effects may I notice from this medicine?

Side effects that you should report to your prescriber or health care professional as soon as possible.

back pain changes обычно называетсяof hearing or ringing in ears changes in vision such as loss of vision, blurred vision, eyes being more sensitive to light, or trouble telling the difference between blue and green objects or objects having a blue color tinge to them chest pain or palpitations difficulty breathing, shortness of breath dizziness eyelid swelling muscle aches prolonged erection (lasting longer than 4 hours) skin rash, itching seizures

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

This list may not describe all possible side effects.

Where can I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Expanded Cinema Re-Enactments

2012-05-23T21:43:00.001-07:00

Since 2003, a big part of Teaching and Learning Cinema’s activity has involved the re-enactment of Expanded Cinema performances from the 1960s and 70s.

As artists, we have discovered that direct access to the work of our aesthetic precursors is essential for understanding, and building upon the work of the past.

However, since many Expanded Cinema events were ephemeral and situated in time and place, they do not easily lend themselves to documentation and archiving.

As a result, the works are poorly represented in art history.

Re-creating them in our own ‘here and now’ is a creative pedagogical process, in which the works become available once again for first-hand experience.

Here are some of the works we have spent time with in recent years. Click on the links for summaries of each of these projects:

Anthony McCall’s Long Film for Ambient Light (1975)

In the early days of Teaching and Learning Cinema (before we used this title) we carried out some very experimental re-enactments of works by VALIE EXPORT, Takehisa Kosugi, and Annabel Nicholson. These were really groping around in the dark, but they set the scene for our more thorough recent activities.

Here’s a poster we made in 2004 describing our approach to these works.

Stop Smoking - American Lung Association

2012-04-10T23:41:00.001-07:00

Every year in the U.S. over 392,000 people die from tobacco-caused disease, making it the leading cause of preventable death. Another 50,000 people die from exposure to secondhand smoke. Tragically, each day thousands of kids still pick up a cigarette for the first time. The cycle of addiction, illness and death continues. What can be done to stop smoking? The American Lung Association is working to strengthen laws and policies that protect everyone from secondhand smoke and prevent young people from starting. We are also committed to helping smokers quit with our smoking cessation programs.

TLC Cooking "Ultimate Guide to Vitamin C"

2012-04-02T22:58:00.001-07:00

Vitamin C, also known as ascorbic acid, is probably one of the most highly publicized, yet least understood, of all of the vitamins. Championed by Nobel laureate Linus Pauling, Ph.D., and advocated by many nutrition buffs, vitamin C is indeed a fascinating and important nutrient (or micronutrient) necessary for human life.

In this article, Dr. Jerry Gordon takes us on a fascinating tour of vitamin C, and shows why this vitamin is so important to your body!

To understand vitamin C, we first need some information about vitamins in general. The word vitamin is derived from the combination of words: vital amine. Vitamins are organic (carbon containing) molecules that mainly function as catalysts for reactions within the body. A catalyst is a substance that allows a chemical reaction to occur using less energy and less time than it would take under normal conditions. If these catalysts are missing, as in a vitamin deficiency, normal body functions can break down and make a person susceptible to disease.

Vitamins are required by the body in tiny amounts (hundredths of a gram in many cases). We get vitamins from three sources:

FoodsBeveragesOur own bodies - vitamin K comes from bacteria within our intestines and vitamin D is produced with the help of ultraviolet radiation on the skin.

Vitamins are either fat-soluble or water-soluble. The fat-soluble vitamins can be remembered with the mnemonic ADEK, for vitamin A, vitamin D, vitamin E, and vitamin K. These vitamins accumulate within the fat stores of the body and within the liver. Fat-soluble vitamins are often associated with toxicity when taken in large amounts. Water-soluble vitamins include vitamin C and the B vitamins. Water-soluble vitamins taken in excess are excreted in the urine and are not usually associated with toxicity. Both vitamin C and the B vitamins are also stored in the liver.

It is interesting to note that most animals produce their own vitamin C. Man, primates (apes, chimps, et cetera) and guinea pigs have lost this ability. Due to this similarity with man, guinea pigs have been subjected to experimentation over the years.

High Quality Medications at HQ-Pharm.com

2012-03-26T22:22:00.001-07:00

What is this medicine?

VARDENAFIL is used to treat erection problems in men. Vardenafil works faster than Sildenafil (Viagra®) and it is less likely to have visual disturbance side effect.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

Take vardenafil tablets by mouth with or without food. The dose is usually taken about 1 hour before sexual activity. Swallow the tablets with a drink of water. Do not take double or extra doses.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply. However, do not take double or extra doses.

What may interact with this medicine?

Do not take vardenafil if you are taking the following medications:

Vardenafil may also interact with the following medications:

What should I watch for while taking this medicine?

Contact your physician immediately if the erection lasts longer than 4 hours or if it becomes painful. This may be a sign of priapism and must be treated immediately to prevent permanent damage.

Do not change the dose of your medication. Please call your prescriber or health care professional to determine if your dose needs to be reevaluated.

Using vardenafil does not protect you or your partner against HIV infection (the virus that causes AIDS) or other sexually transmitted diseases.

What side effects may I notice from this medicine?

Side effects that you should report to your prescriber or health care professional as soon as possible.

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

This list may not describe all possible side effects.

Where can I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

About Us

2012-03-19T10:35:00.001-07:00

At Henry's Diner, you will feel at home in our non-smoking and relaxed environment. If you're not a morning person, that's okay, we serve breakfast all day long for your convenience. If you're unsatisfied with your food, just let your server know and we'll gladly fix it! Our diner has an updated retro–style look with booths, counter seating, and tables for you to enjoy. We provide late night dining on weekends, carryout orders, and gift certificates. Present this coupon for $1.00 off your next visit. Henry's Diner is a historic landmark located near The Church Street Market Place® and Urban Outfitters®. Reserve a spot today and find out why our customers say "We appreciate the clean bright atmosphere, the food is always good and very friendly staff!"

My Canadian Pharmacy - Tramadol - Order Now!

2012-03-15T22:16:00.001-07:00

Tramadol (brand names include: Tramjet / Adolan / Anadol / Contramal / Dolol / Dolzam / Dromadol / Ixprim / Ralivia / Tramadex / Tramal / Tridural / Utram / Ultram ER / Zamadol / Zydol / Zytrim / Zendol-SR) is a pain relief medication that is meant to help alleviate moderate to moderately severe pain.

Tramadol is a synthetic analgesic, not an anti-inflammatory, which means that people who cannot take anti-inflammatories due to the side effects can often take Tramadol to help relieve their pain.

Tramadol does not have gastrointestinal side effects associated with NSAIDs (nonsteroidal anti-inflammatory drugs).

Tramadol

2012-03-15T16:14:00.001-07:00

Tramadol is used to relieve moderate to moderately severe pain. Tramadol extended-release tablets are only used by people who are expected to need medication to relieve pain around-the-clock for a long time. Tramadol is in a class of medications called opiate agonists. It works by changing the way the body senses pain.

Tramadol comes as a tablet and an extended-release (long-acting) tablet to take by mouth. The regular tablet is usually taken with or without food every 4-6 hours as needed. The extended-release tablet should be taken once a day. Take the extended-release tablet at about the same time of day every day, and either always take it with food or always take it without food. Take tramadol exactly as directed. Do not take more medication as a single dose or take more doses per day than prescribed by your doctor. Taking more tramadol than prescribed by your doctor may cause serious side effects or death.

Your doctor may start you on a low dose of tramadol and gradually increase the amount of medication you take, not more often than every 3 days if you are taking the regular tablets or every 5 days if you are taking the extended-release tablets.

Swallow the extended-release tablets whole; do not split, chew, or crush them. Do not snort (inhale powder from crushed tablet) or inject the dissolved extended-release tablets. Taking this medication in a way that is not recommended may cause serious side effects or death.

Tramadol can be habit-forming. Do not take a larger dose, take it more often, or take it for a longer period of time than prescribed by your doctor. Call your doctor if you find that you want to take extra medication or if you notice any other unusual changes in your behavior or mood.

Do not stop taking tramadol without talking to your doctor. Your doctor will probably decrease your dose gradually. If you suddenly stop taking tramadol you may experience withdrawal symptoms such as nervousness; panic; sweating; difficulty falling asleep or staying asleep; runny nose, sneezing, or cough; numbness, pain, burning, or tingling in your hands or feet; hair standing on end; chills; nausea; uncontrollable shaking of a part of your body; diarrhea; or rarely, hallucinations (seeing things or hearing voices that do not exist).

This medication is sometimes prescribed for other uses; Аск your doctor or pharmacist for more information.

Before taking tramadol, tell your doctor and pharmacist if you are allergic to tramadol or other opiate pain or cough medications such as meperidine (Demerol), morphine (Avinza, Kadian, MS Contin), codeine (in some pain medications and cough syrups), hydrocodone (in Vicodin), hydromorphone (Dilaudid), oxycodone (OxyContin, in Percocet), propoxyphene (Darvon, Darvon N, in Darvocet), any other medications, or any of the ingredients in tramadol tablets or extended-release tablets. Конечно, аск your pharmacist for a list of ingredients in tramadol tablets or extended release tablets. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking. Be sure to mention any of the following: antifungal medications such as ketoconazole (Nizoral); digoxin (Lanoxin); erythromycin (E.E.S., E-Mycin, Erythrocin); monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate); medications for anxiety, mental illness, nausea, and pain; medications for seizures, such as carbamazepine (Tegretol); muscle relaxants such as cyclobenzaprine (Flexeril); promethazine (Phenergan); quinidine; rifampin (Rifadin, Rifamate, Rimactane, others); sedatives; sleeping pills; selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft); tranquilizers; tricyclic antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil);and warfarin (Coumadin). Many other medications may also interact with tramadol, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor what herbal products you are taking, especially St. John's wort. tell your doctor if you have or have ever had seizures; an infection in your brain or spine; a head injury, a brain tumor, a stroke, or any other condition that caused high pressure inside your skull; depression or thoughts about harming or killing yourself or planning or trying to do so; diabetes; breathing problems or lung disease; or kidney or liver disease. Also tell your doctor if you drink or have ever drunk large amounts of alcohol, use or have ever used street drugs, or have overused prescription medications. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking tramadol, call your doctor. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking tramadol. you should know that this medication may make you drowsy and may affect your coordination. Do not drive a car or operate machinery until you know how this medication affects you. talk to your doctor about the safe use of alcohol while you are taking this medication. Alcohol can make the side effects from tramadol worse. you should know that tramadol may cause dizziness, lightheadedness, and fainting when you get up from a lying position. To avoid this, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

Talk to your doctor about drinking grapefruit juice while you are taking this medication.

If your doctor has told you to take tramadol regularly, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Tramadol may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: Some side effects can be serious. If you experience any of these symptoms or those listed in the SPECIAL PRECAUTIONS section , call your doctor immediately:

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch ] or by phone [1-800-332-1088].

Tramadol may cause other side effects. Tell your doctor if you have any unusual problems while you are taking this medication.

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

Phthalates in cosmetics and beauty products | Environmental Working Group

2012-03-06T02:12:00.001-08:00

It is remarkable that such a heavily used chemical, with known toxicity, can be so poorly regulated. For example, Procter & Gamble holds a patent which proposes to add 5 milligrams of DBP to each dose of an oral pharmaceutical. A woman of average weight (140 pounds) ingesting this tablet would get a daily dose of DBP that is 80 percent of her current allowable daily dose defined by the RfD. She would get double the dose that would be allowed if the RfD were updated to protect the male fetus from birth defects, assuming no other exposure to DBP in other products.

The Environmental Working Group conducted a web-based analysis to locate consumer products, particularly cosmetics and beauty aids, containing phthalates. We found both dibutyl phthalate (DBP) and diethyl phthalate (DEP) in numerous products, and butylbenzyl phthalate (BBP) in a smaller number of products. Ultimately we limited our search to DBP, because it is a more potent reproductive and developmental toxin than DEP, and is found in a greater number of products than BBP.

Several points became clear during our product search. First, alternatives to phthalates are readily available to industry, as only a fraction of any given type of cosmetic or beauty product contains phthalates.

Second, women have no practical way to choose products that are phthalate-free. Some cosmetics contain ingredient labels on the outside of the product, but the print is so small as to be nearly unreadable, and a typical shopper will not know that "dibutyl phthalate" is the same thing as "butyl ester" or even possibly "plasticizer." Other products, such as more expensive perfumes, contain ingredient labels inside the packaging where they cannot be read until after the product is purchased. We found still other products on store shelves, particularly imported products, that lacked ingredient labels altogether, in direct violation of federal regulations.

Third, with information currently in the public arena, it is nearly impossible to develop anything approaching a comprehensive list of cosmetic and beauty products that contain phthalates. This would require a product-by-product, label-by-label search of every single cosmetic and personal care box and bottle sold in the United States. The results of our analysis only scratch the surface of what will be a daunting task for CDC as they try to define exactly where women of childbearing age are being exposed to phthalates.

As a first step in discovering some of the beauty and personal care products that contain DBP, the Environmental Working Group (EWG) shopped at a local Rite-Aid, surfed the он-лайн store Drugstore.com, and searched the U.S. patent office records for products that contain DBP in the patent application. We found that DBP may be used in a broad range of beauty and personal care products, including shampoos and conditioners, lotions, hair growth formulations, antiperspirants, and sunscreen. It can even be used in gum, candy and pharmaceuticals taken orally.

Our product label searches in electronic and real-world drugstores showed that, for the consumer, the products most easily found that contain DBP are nail enamels and hardeners. In a limited label search of nail products on online drugstore интернет sites, EWG found DBP in a wide variety of name brand items, including Cover Girl and Maybelline nail enamels (Table 3).

The difficulty of compiling comprehensive lists of phthalate-containing cosmetics, from label searches alone, led us to conduct a web-based patent search to discover which companies claimed cosmetic-related inventions that included phthalates as ingredients. As of October 5, 2000, the U.S. Patent and Trademark Office had records of 309 patents related to cosmetics that included DBP as an essential or optional ingredient, or as an ingredient in an example product formulation. Thirty-eight individual companies or inventors hold 105 recent cosmetic-related patents that propose DBP as an additive (Table 4).

In some patents, companies gave information on the percent by weight of DBP proposed to be added to the product. DBP in nail polishes tends to be added at about five percent by weight (for example, Maybelline nail enamel patent 5972095), but DBP in other products ranged up to 20 percent, in a night cream invented by the Japanese company Shiseido (patent number 5891846) (Table 5).

Why the cosmetic industry adds phthalates to their products Multiple chemical properties of DBP make it a useful additive in many types of cosmetics. These properties include its ability to impart flexibility to thin films for mascara and nail polish, its oily texture that makes skin feel soft, and its ability to make lotions penetrate deeper into the skin (Table 6).

DBP as a plasticizer in nail enamel The plasticizing and film-formation properties of DBP make the chemical particularly useful for nail polish. After nail polish is applied, some of the ingredients volatilize and leave behind a film that is the coating over the nail. DBP is one of the ingredients left behind, reducing brittleness and cracking in the polish.

If the DBP stayed intact in the polish, women might absorb negligible amounts of the chemical into their bodies. But a group of scientists in Hamburg, Germany showed that water-soluble components of the polish, like DBP, are dissolved out of the polish each time they contact water, a conclusion they reached after measuring the leaching of DBP from nail polish that had dried for three days. In fact, one of the reasons nail polish eventually chips is that it becomes brittle as DBP is leached out of the film. This means that every time a woman washes her hands, DBP is washed out of her nail polish and contacts her skin. The scientists conclude that "water-soluble components... attain the skin during extensive but transient contact." Therefore, a woman wearing nail polish not only can absorb DBP through her nail, but also has multiple opportunities to absorb DBP directly through her skin.

Since the 1940's scientists have known that nail polish contains allergenic ingredients (Sainio et al 1997). Some companies are beginning to study formulations of nail polish that have reduced quantities of DBP, because of concerns over allergic reactions. The well-known French cosmetics company L'Or?al, in patent number 5,676,935, claims "Nowadays, it is preferable to use plasticizers other than phthalates in varnishes for reasons of allergy..." In fact, allergic responses to DBP can be severe. In a 1999 case study published in the journal Dermatology, the authors describe a case of anaphylactic shock, a severe allergic reaction, in a patient exposed to DBP in the coating of an oral pharmaceutical (Gall et al 1999).

The ability of DBP to cause allergic reactions means that the chemical can induce a state of hypersensitivity in the immune system. Environmental antigens such as DBP can cause the immune system to respond to chemical exposures with immunological reactions that are harmful, varying from hives to life-threatening responses such as anaphylactic shock, where low blood pressure and breathing difficulties can result in death.

L'Or?al USA is still using DBP in their nail products - for example, in their Maybelline Express Finish Fast-Dry, Ultimate Wear, and Salon Finish nail enamels that EWG found on the shelves of a Rite-Aid drugstore in Washington DC, in September 2000. Even DBP's well-recognized effects on the immune system have not been enough to change manufacturers' practices.

DBP as a "penetration enhancer" Both Elizabeth Arden Company (New York, New York) and Chesebrough Ponds (Greenwich, Connecticut) hold patents for cosmetics in which DBP is proposed as a penetration enhancer.

Elizabeth Arden proposes DBP as an additive to skin care products, where DBP is used to get more of the product deeper into the skin: "improving [the product's] delivery through the stratum corneum to its site of action in the epidermis." Similarly, Chesebrough Ponds proposes that DBP can be added to a hair growth formulation for men to help the formulation penetrate deeper into the scalp to the site of action at the hair follicles.

Research from the chemical giant Zeneca gives more evidence that DBP acts as a penetration enhancer. Their work shows that when DBP is added to products for the skin, allergic reactions are more severe (in this case, to ingredients other than DBP). The scientists postulate that the enhanced allergic reactions stem from DBP's ability to deliver the chemicals deeper into the skin (Dearman et al 1996).

The use of DBP as a penetration enhancer stands in direct contrast to CERHR's assertion that "Dermal contact with products containing DBP is possible, but absorption through the skin is most likely minimal." The Center cites a study of DBP migration through rat skin. CDC, on the other hand, upon discovering high levels of DBP in women of childbearing age, postulates that dermal absorption is playing a role: "Dermal absorption also occurs at a significant rate for phthalates with short side chains such as ...DBP...," citing the same rat study as evidence (Blount et al 2000).

Regardless of how various government agencies are interpreting the dermal absorption study in rats, industry continues to use DBP specifically for its ability to absorb deep into the skin.

DBP as a humectant and emollient DBP is listed as a humectant or emollient in patents from Procter & Gamble Company (Cincinnati, OH), Lever Brothers Company Inc (New York, NY), Colgate Palmolive Company (New York, NY), Kraft General Foods (Northfield, IL), Anheuser-Busch, Incorporated (St Louis, MO) and four other companies. Humectants are skin moisturizers; emollients soften the skin. Information in patents from these major companies indicate that DBP is added to skin care products because its oily texture gives the impression that the skin itself is soft and moisturized, when in fact it is the DBP residue that makes the skin feel this way.

Tramadol

2012-02-28T01:38:00.001-08:00

Brand names: ConZip, Rybix ODT, Ryzolt, Ultram, Ultram ER

What is tramadol?

Tramadol is a narcotic-like pain reliever.

Tramadol is used to treat moderate to severe pain. Tramadol extended-release is used to treat moderate to severe chronic pain when treatment is needed around the clock.

Tramadol may also be used for other purposes not listed in this medication guide.

You should not take this medication if you are allergic to tramadol, if you have ever been addicted to drugs or alcohol, or if you have ever attempted suicide. Do not take tramadol while you are intoxicated (drunk) or taking any of the following: alcohol or street drugs, narcotic pain medicine, sedatives or tranquilizers, or medicine for depression, anxiety, or mental illness.

Seizures (convulsions) have occurred in some people taking this medicine. Tramadol may be more likely to cause a seizure if you have a history of seizures or head injury, a metabolic disorder, or if you are taking certain medicines such as antidepressants, muscle relaxers, narcotic, or medicine for nausea and vomiting.

Seek emergency medical attention if you think you have used too much of this medicine. A tramadol overdose can be fatal.

Tramadol may be habit-forming and should be used only by the person it was prescribed for. Keep the medication in a secure place where others cannot get to it.

You should not take this medication if you are allergic to tramadol, if you have ever been addicted to drugs or alcohol, or if you have ever attempted suicide.

Do not take tramadol while you are intoxicated (drunk) or taking any of the following:

Seizures have occurred in some people taking tramadol. Talk with your doctor about your seizure risk, which may be higher if you have:

To make sure you can safely take tramadol, tell your doctor if you have any of these other conditions:

Tramadol may be habit forming and should be used only by the person it was prescribed for. Never share tramadol with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

FDA pregnancy category C. It is not known whether tramadol will harm an unborn baby. Tramadol may cause serious or fatal side effects in a newborn if the mother uses this medication during pregnancy or labor. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Tramadol can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are taking tramadol. Do not give this medication to anyone younger than 16 years old without the advice of a doctor.

Rybix ODT may contain phenylalanine. Talk to your doctor before using this form of tramadol if you have phenylketonuria (PKU).

How should I take tramadol?

Take tramadol exactly as prescribed. Never take tramadol in larger amounts, or for longer than recommended by your doctor. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Tramadol can be taken with or without food, but take it the same way each time.

Do not crush, chew, or break a tramadol tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time. This medicine is for oral (by mouth) use only. Powder from a crushed tablet should not be inhaled or diluted with liquid and injected into the body. Using this medicine by inhalation or injection can cause life-threatening side effects, overdose, or death.

To take tramadol orally disintegrating tablets (Rybix ODT):

If you use the tramadol extended-release tablet, the tablet shell may pass into your stools (bowel movements). This is normal and does not mean that you are not receiving enough of the medicine.

Do not stop using tramadol suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication.

Store tramadol at room temperature away from moisture and heat. Keep track of the amount of medicine used from each new bottle. Tramadol is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A tramadol overdose can be fatal.

Overdose symptoms may include extreme drowsiness, shallow breathing, muscle weakness, slow heartbeat, cold or clammy skin, fainting, or seizure.

What should I avoid while taking tramadol?

Do not drink alcohol. It may cause a dangerous decrease in your breathing when used together with this medicine. Tramadol may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Get emergency medical help if you have any of these signs of an allergic reaction to tramadol: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using tramadol and call your doctor at once if you have any of these serious side effects:

Less serious tramadol side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

For mild to moderate severe chronic pain not requiring rapid onset of analgesic effect:

Titration: increase in 25 mg increments as separate doses every 3 days to reach Сто mg per day taken as 25 mg 4 times per day. Then the total daily dose may be increased by 50 mg as tolerated every 3 days to reach 200 mg per day taken as 50 mg 4 times per day.

Maintenance: After titration, tramadol 50 mg to Сто mg can be administered as needed for pain relief every 4 to 6 hours not to exceed Четыресто mg per day.

For the management of moderate to moderately severe chronic pain in adults who require around-the-clock treatment of their pain for an extended period of time:

Extended-Release Tablets:

Initial Dose: Сто mg once daily and titrated up as necessary by Сто mg increments every five days to relief of pain and depending upon tolerability.

Maximum Dose: Extended-release tablets should not be administered at a dose exceeding 300 mg per day.

For patients in whom rapid onset of analgesic effect is required and for whom the benefits outweigh the risk of discontinuation due to adverse events associated with higher initial dose:

Dose: 50 mg to Сто mg can be administered as needed for pain relief every 4 to 6 hours, not to exceed Четыресто mg per day.

For patients over 65 years:

Dose selection should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function and of concomitant disease or other drug therapy.

For patients over 75 years:

Maximum dose of regular oral tablets: 300 mg per day in divided doses

16 years old and up:

Titrate by Сто mg increments every 2 to 3 days if needed for pain control

What other drugs will affect tramadol?

You may be more likely to have a seizure (convulsions) if you take tramadol while you are using certain other medicines. Do not take tramadol without telling your doctor if you also use any of the following medications:

Cold or allergy medicine, sleeping pills, muscle relaxers, and medicine for seizures or anxiety can add to sleepiness caused by tramadol. Tell your doctor if you regularly use any of these medicines, or any other pain medication.

Tell your doctor about all other medicines you use, especially:

This list is not complete and there are many other drugs that can interact with tramadol. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.