Pharmacy Stuff

New Drug Offers Alternative to Warfarin

2011-03-04T10:44:00.000-08:00

Dabigatran effective in prevention of blood clots for patients with atrial fibrillation

MONDAY, Feb. 14 (HealthDay News) -- The American College of Cardiology Foundation (ACCF) and the American Heart Association (AHA) have issued an updated guideline, describing the newly approved medication dabigatran as an alternative to warfarin for patients with atrial fibrillation who need anticoagulation therapy; the guideline update has been published online Feb. 14 in Circulation.

L. Samuel Wann, M.D., of the Wisconsin Heart and Vascular Clinics in Milwaukee, and colleagues, all of whom are members of the ACCF/AHA Task Force on Practice Guidelines, updated the section of the guidelines that addresses the emerging antithrombotic drugs for the management of atrial fibrillation.

The task force members reported that dabigatran was an effective alternative to warfarin for the prevention of stroke and blood clots in patients with paroxysmal or permanent atrial fibrillation, and in those who have risk factors for stroke or blood clots. The recommendations were based on the Randomized Evaluation of Long-Term Anticoagulation Therapy trial, which found that dabigatran offered either noninferior or greater stroke prevention and did not increase or decreased the incidence of major bleeding. They also stated that dabigatran was not for use among patients with prosthetic heart valves, significant heart valve disease, severe renal failure, or advanced liver disease.

"Dabigatran etexilate was approved by the U.S. Food and Drug Administration on Oct. 19, 2010, for marketing in the United States for the prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. Dabigatran is the first new oral anticoagulant to become available for clinical use in more than 50 years," the authors write.

Several of the guideline authors disclosed financial relationships with Boehringer Ingelheim and other pharmaceutical and medical device companies.

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Oxford Handbook of Practical Drug Therapy

2011-02-26T11:39:00.000-08:00

Oxford Handbook of Practical Drug Therapy
By Duncan Richards, Jeffrey Aronson

Book Detail
Publisher: Oxford University Press, USA
Publication Date: 2005-06-16
ISBN-10 / ASIN: 0198530072
ISBN-13 / EAN: 9780198530077
Number Of Pages: 720 Pages
Format: CHM
File Size: 23.6 Mb

Book Intro
The overall structure of this handbook is similar to that of the British National Formulary, with monographs arranged broadly by therapeutic category. When a drug has several different uses, these are brought together in a single monograph; this will allow the reader to appreciate in full range of actions, whether therapeutic or adverse. The safe and effective use of medicines requires a sound knowledge of pharmacology. When a drug illustrates a particular pharmacological principle, this is expanded on in the teaching point section at the end of the monograph. As readers use the book, they will increase their basic knowledge in this practical way.

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Oxford Handbook of Respiratory Medicine

2011-02-26T11:36:00.000-08:00

Oxford Handbook of Respiratory Medicine
by Stephen Chapman, Grace Robinson, John Stradling, Sophie West

Book Detail
Publisher: Oxford University Press, USA
Publishing: 2005-08-23
ISBN: 0198529775
Number of Pages: 776 Pages
Format: CHM
File Size: 4.80 MB

Book Intro

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Oxford Handbook of Genitourinary Medicine, HIV, and AIDS

2011-02-26T11:33:00.000-08:00

Oxford Handbook of Genitourinary Medicine, HIV, and AIDS
By Richard Pattman, Michael Snow, Pauline Handy, K Nathan Sankar, Babiker Elawad

Book Detail
Publisher: Oxford University Press, USA
Publication Date: 2005-09-01
ISBN-10 / ASIN: 0198520778
ISBN-13 / EAN: 9780198520771
Number Of Pages: 580 Pages
Format: CHM
File Size: 3.38

Book Intro
Genitourinary medicine (GUM) is an expanding specialty which is primarily related to the treatment and prevention of sexually transmitted infections (STIs). A number of GUM departments also offer other sexual health services such as contraception, sexual dysfunction and health promotion. Services are provided by multidisciplinary teams which include doctors, nurses, health advisers (who carry out partner notification and counselling), receptionists, laboratory staff and secretarial support. The Oxford Handbook of Genitourinary Medicine HIV and AIDS provides practical, evidence-based information on the specialty, covering medico-legal, ethical, and procedural issues. The first section deals with routine management, special situations and clinical and laboratory processes. The second section covers genitourinary conditions in a disease-orientated style, including sexually transmitted diseases and other genitourinary problems. The third section on HIV provides a contemporary epidemiological overview of this infection, basic viral biology and pathogenesis, a disease-orientated description of conditions both directly related and opportunistic, and their management, and data on special situations such as pregnancy.

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Oxford Handbook of Clinical Haematology 2nd Edition

2011-02-26T11:30:00.000-08:00

Oxford Handbook of Clinical Haematology 2nd Edition
By Drew Provan, Charles R. J. Singer, Trevor Baglin, John Lilleyman

Book Detail
Publisher: Oxford University Press, USA
Publication Date: 2004-04-08
ISBN-10 / ASIN: 0198526520
ISBN-13 / EAN: 9780198526520
Number Of Pages: 736 Pages
Format: PDF
File Size: 8.83 Mb

Book Intro
The Oxford Handbook of Clinical Haemotology continues to provide the essential core knowledge needed in modern clinical practice for the diagnosis and management of patients with possible disorders of the blood. Major advances in the specialty have been reflected in this thoroughly revised new edition. Essential knowledge is covered with the main differential diagnoses, along with relevant investigations that will help the junior doctor to arrive at a definitive diagnosis. The management of the patient is provided in a way that allows the junior to initiate treatment whilst waiting for review of the patient by a senior member of staff.
As with the first edition, the new edition of this Handbook will have wide appeal and readership amongst senior medical undergraduates, junior doctors and trainees in haemotology, residents, interns and fellows, family doctors, intensive care staff and specialist nurses.

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Oxford Handbook of Oncology

2011-02-26T11:26:00.000-08:00

Oxford Handbook of Oncology
by Jim Cassidy, Donald Bissett, Roy Spence, Miranda Payne

Book Detail
Publisher: Oxford University Press, USA
Publication Date: 2002-06-15
ISBN-10 / ASIN: 0192630350
ISBN-13 / EAN: 9780192630353
Number Of Pages: 704 Pages

Book Intro
The new addition to the Oxford Handbook series, the Oxford Handbook of Oncology, will serve as a practical guide to clinical consultation in oncology, covering the scientific basis as well as diagnosis, investigation, management and palliative care issues in cancer. Key information is provided in an easy-to-use format and each section is designed to give the reader sufficient background, understanding vocabulary in the topic to allow further in-depth study. Diseases are dealt with systematically and the bulk of the text is dedicated to specific malignancies emphasizing the more common malignancies. This pocket handbook will appeal to medical staff (both junior and senior) in oncology/palliative care and related disciplines which have a significant amount of malignant disease.

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Oxford Handbook of Urology

2011-02-26T11:23:00.000-08:00

Oxford Handbook of Urology
by John Reynard, Simon Brewster, Suzanne Biers

Book Detail
Publisher: Oxford University Press, USA
Publication Date: 2005-12-09
ISBN-10 / ASIN: 0198530951
ISBN-13 / EAN: 9780198530954
Number Of Pages: 698 Pages
Format: CHM
File Size: 10.8 MB

Book Intro
Approximately 20% of all surgical operations and a similar percentage of surgical emergencies are urological in nature. However, often doctors have very limited experience of the many common and varied conditions encountered in this important surgical specialty. For the doctor or nurse expected to provide the initial assessment and management of a condition with which he or she has had very limited experience, this book provides an invaluable source of information and advice. This applies not only to SHOs and specialist registrars on urology and surgical rotations, but also to General Practitioners, Accident and Emergency staff and the growing number of urological specialist nurses. This handbook provides a comprehensive summary of urological disease and its management, in a form that is concise, relevant to the target audience and readily available. While the description of urological conditions is comprehensive, the emphasis is on the practical approach to the conditions which are likely to be encountered. The significance and appropriate management of common symptoms is described, providing (on a single page) a summary of the essential approach to a specific presenting complaint, be that haematuria, scrotal pain or bedwetting. Common urological operations are described, to allow the General Practitioner, Accident and Emergency doctor, nurse or surgical trainee, rapid access to information concerning indications, pre-operative assessment, consent, and complications and their management.

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Oxford Handbook of Clinical Surgery 3rd Edition

2011-02-26T11:20:00.000-08:00

Oxford Handbook of Clinical Surgery 3rd Edition
By Greg McLatchie, Neil Borley, Joanna Chikwe

Book Detail
Publisher: Oxford University Press, USA
Publication Date: 2008-02-09
ISBN-10 / ASIN: 0198568258
ISBN-13 / EAN: 9780198568254
Number Of Pages: 664 Pages
Format: CHM
File Size: 5.09 MB

Book Intro
Thoroughly revised with a wide range of new topics, presentations, and a new layout to aid quick reference, the new edition of this bestselling Oxford Handbook serves as an accessible pocket reference for junior surgical trainees, medical students, nursing, paramedical and rehabilitation staff. It covers the assessment and preparation of the patient, anesthesia and critical care, inflammation, wound healing and infection, and the key components of general surgical practice as well as chapters on other surgical specialties, including plastic, pediatric and orthopedic surgery. There are step by step descriptions of common operative surgical techniques, practical hints and procedures, and information on signs, symptoms and rarities. Emergency presentations are clearly identified for rapid reference and investigations and management plans are set out in a clear and easy to follow way. Surgically relevant anatomy and physiology is provided for each area, quick reference symbols ensure the reader is guided to key facts and there is an increased focus on evidence-based practice throughout. A cut above the rest, this is the essential guide to clinical surgery and the surgical
specialties.

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Oxford Handbook of General Practice 2nd Edition

2011-02-26T11:16:00.000-08:00

Oxford Handbook of General Practice 2nd Edition
By Chantal Simon, Hazel Everitt, Tony Kendrick

Book Detail
Publisher: Oxford University Press, USA
Publication Date: 2005-12-15
ISBN-10 / ASIN: 019856581X
ISBN-13 / EAN: 9780198565819
Number Of Pages: 1148
Format: CHM
File Size: 11.8 MB

Book Intro
A lifeline for the busy GP, the Oxford Handbook of General Practice covers the whole of general practice. It includes hands-on advice and allows rapid access to information to help with any day-to-day problems which might arise in general practice.
The general practice section has been revised to include the new General Medical Services contract and appraisal and revalidation. There are new chapters on complementary medicine, chronic disease management and elderly care and increased emphasis on evidence based medicine, sports medicine and practice in a multicultural society. Pointers to further information for GPs and advice and support for patients, which can be easily accessed from the GP surgery, are included throughout.
The layout of the handbook has been redesigned with the use of colour-coding to aid quick reference and additional flow charts, tables and diagrams have been included to make information easier to access.
It is the essential handbook for all practising GPs, GPs in training, medical students and allied health professions.

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Oxford Handbook of Medical Sciences

2011-02-26T11:12:00.000-08:00

Oxford Handbook of Medical Sciences
By Simon Cross, Ian Megson, David Meredith, Robert Wilkins

Book Detail
Publisher: Oxford University Press, USA
Publication Date: 2006-08-24
ISBN-10 / ASIN: 0198528299
ISBN-13 / EAN: 9780198528296
Number Of Pages: 952
Format: CHM
File Size: 27.4 MB

Book Intro
Increasingly, students are starting medical school without a specific background. The Oxford Handbook of Medical Sciences has been written by biomedical scientists and clinicians to explain the fundamental scientific principles that underpin clinical medicine, and to provide students with a firm grounding in the basic sciences. Frequent cross-referencing with the Oxford Handbook of Clinical Medicine helps to highlight the clinical relevance of specific issues. Deliberately divided into systems-based sections that mirror modern medical teaching strategies, this handbook begins with a clear, easily digestible account of basic cell physiology and biochemistry. It then moves on to an investigation of the traditional piers of medicine (anatomy, physiology, biochemistry, pathology, and pharmacology) integrated in the context of each of the major systems relevant to the human body. Well illustrated with clear diagrams and color images, it will prove especially useful for students on problem-based learning courses who are in need of a concise and user-friendly book, and will also serve as a refresher for those doing membership exams.

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Oxford Handbook of Clinical Diagnosis

2011-02-26T11:09:00.000-08:00

Oxford Handbook of Clinical Diagnosis
By Huw Llewelyn, Hock Aun Ang, Keir E. Lewis, Anees Al-Abdulla

Book Detail
Publisher: Oxford University Press, USA
Publication Date: 2006-03-30
ISBN-10 / ASIN: 0192632493
ISBN-13 / EAN: 9780192632494
Number Of Pages: 728
Format: CHM
File Size: 1.04 MB

Book Intro
The Oxford Handbook of Clinical Diagnosis helps the reader to interpret symptoms, physical signs and initial test results and to allow students (or doctors not familiar with all aspects of medicine) to arrive at diagnoses logically and to explain their reasoning confidently. The book starts with a review of the techniques of history taking and examination, with hints on how to interpret the information and practical advice on the diagnostic process. The bulk of the book is divided by body system and describes the findings that can emerge at each stage of the assessment process. The main differential diagnoses of significant findings are given as a starting point for the diagnostic reasoning process. With each diagnosis is listed the findings which suggests that the diagnosis might be present and the evidence which confirms the diagnosis. This unique book concentrates entirely on the diagnosis, referring readers to the Oxford Handbook of Clinical Medicine and Oxford Handbook of Clinical Specialties for management information. It will also train readers to describe the diagnosis and reasoning behind it to a patient, relative, peer, or senior colleague.

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Oxford Handbook of Clinical and Laboratory Investigation

2011-02-26T11:05:00.000-08:00

Oxford Handbook of Clinical and Laboratory Investigation 2nd Edition
By Drew Provan

Book Detail
Publisher: Oxford University Press, USA
Publication Date: 2005-11-24
Language: English
ISBN-10 / ASIN: 0198566638
ISBN-13 / EAN: 9780198566632
Number Of Pages: 838
Format: PDF
File Size: 12.4 MB

Book Intro
Modern medicine is highly complex and investigations are a key part of the diagnostic process. With major advances in technology there are thousands of clinical and laboratory tests available. This book provides a patient-oriented approach to investigation (first part of book) where key symptoms and signs are described along with tests that may be of value in reaching a diagnosis. The remainder of the book is specialty-centered and provides a comprehensive review of all available tests within a given subject. The book emphasizes which tests are of value, when tests are not likely to be helpful, along with pitfalls in the interpretation of results. The aim is of the book is to provide a more rational method of investigation and prevent over-investigation which is expensive for the hospital and unpleasant for the patient. The contributors are all active clinicians who are engaged in medical practice, so appreciate the problems faced by junior doctors. The book should also be of value to senior medical students who will be facing finals examinations, and who will soon be on the wards and responsible for ordering tests on their patients

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Oxford Handbook of Clinical Examination and Practical Skills

2011-02-26T10:49:00.000-08:00

Oxford Handbook of Clinical Examination and Practical Skills
by James Thomas, Tanya Monaghan

Book Detail
Publisher: Oxford University Press, USA; 1 edition (July 12, 2007)
Language: English
ISBN-10: 019856838X
ISBN-13: 978-0198568384
Number of Pages: 704
Format: CHM
Size: 31.5 MB

Book Intro
Your one-stop-shop for final examination, the Oxford Handbook of Clinical Examination and Practical Skills is the first truly comprehensive pocket guide to clinical examination and practical skills for medical students and junior doctors. Providing clear and user-friendly guidance on all aspects of history taking, physical examination, common practical procedures, data interpretation and communication skills, it gives realistic advice on coping with common situations. In line with current teaching methods, the book takes a systems-based approach to medicine. Each system chapter follows a structured format covering applied anatomy, history, examination, and the presentation of common and important disorders. The procedures section includes approximately forty practical procedures that the final year medical student and senior nurse are expected to perform, from hand-washing through cardiopulmonary resuscitation to inserting chest drains. The theory, practice and complications are outlined for each. The final section on data interpretation covers the basics of chest x-rays, abdominal x-rays, ECGs, lung function tests and several other areas that the junior doctor is expected to carry out in their early years of training. Aimed at medical students throughout their course and student nurses throughout their clinical years, its clear presentation and layout combined with comprehensive clinical detail make this book an ideal guide both for quick reference whilst on the wards, or for more detailed study at the desk. It will also prove useful to junior doctors and nurse practitioners as a primer before going out onto wards, or into a primary care setting.

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Oxford Handbook of Anaesthesia

2011-02-26T10:35:00.000-08:00

Oxford Handbook of Anesthesia
By Keith Allman, Iain Wilson

Book Detail
Publisher: Oxford University Press, USA
Publication Date: 2006-06-08
ISBN-10 / ASIN: 0198566093
ISBN-13 / EAN: 9780198566090
Number Of Pages: 1228
Format: CHM
File Size: 6.30 MB

Book Intro
The Oxford Handbook of Anesthesia has been completely updated for the second edition. All chapters have been rewritten and a number of new expert authors have been brought on board. Additional new material includes anesthesia for the critically ill, and a comprehensive section on anesthetic risk including anesthetic risk tables. The first section deals with preoperative issues affecting the administration of anesthesia. Practical advice is provided covering the impact of medical disease on anesthesia. The second section describes practical anesthetic techniques for surgical specialties, including most sub specialties such as thoracic and neuroanaesthesia. Separate, comprehensive sections on pediatric and obstetric anesthesia are included. The management of emergencies arising during anaesthesia are fully covered with helpful action plans and algorithms throughout. Uncommon conditions and their management are included, and there is an extensive drug formulary and guide to infusion drugs. As with the first edition, this new edition will be the essential handbook for anaesthetists, both junior and experienced, for registrars and those sitting exams, as well as ODPs and nurses involved in theater area work and pre-assessment. It is the one book for anyone working in anesthesia to keep to hand at all times!

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Oxford Handbook of Acute Medicine

2011-02-26T08:28:00.000-08:00

Oxford Handbook of Acute Medicine 2nd Edition
Edited by Punit S. Ramrakha, Kevin P. Moore

Book Detail
Publisher: Oxford University Press, USA
Publishing Date: 2004-10-14
ISBN:0198520727
Format: CHM
File Size: 5.3 MB

Book Intro
The management of acute medical emergencies is the most demanding and stressful aspect of medical training. Most textbooks of medicine can only go into general detail about the management of medical emergencies, and it is difficult for the practicing doctor to keep up-to-date with the latest guidelines while doing a busy clinical job. The Oxford Handbook of Acute Medicine is an up-to-date, practical and comprehensive guide to the management of the acutely ill patient. The book relates pathophysiology to clinical features to help the reader make the diagnosis quickly. It identifies priorities for treatment and leads the reader, step-by-step, through the management of the patient while awaiting specialist help. Wherever possible, published guidelines have been incorporated to ensure that the book reflects current, recommended management of medical emergencies, with evidence-based treatments. Details of specialist treatments are included to inform readers about the patient's likely ongoing care. The layout of the book reflects clinical practice: topics are divided into assessment, differential diagnosis, immediate management and ongoing treatment. There is an extensive section on practical procedures. It is the ideal companion for students (keen to understand the management of patients they see during their training), practicing physicians at all levels from recently qualified doctors to consultants (to brush upon the modern management of acute medical conditions), staff in A and E who see acutely ill patients daily, and nurses caring for acutely ill patients.

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Nuclear Medicine Therapy by Janet & Winfried

2011-02-26T01:59:00.000-08:00

Nuclear Medicine Therapy by Janet & Winfried

Book Detail
Publisher: Informa Healthcare
Publication Date: 2007-03-30
ISBN / ASIN: 0824728769
EAN: 9780824728762
Language: English
Number Of Pages: 216 Pages
Format: PDF
File Size: 11.3 MB

Book Intro
One in three of the 30 million Americans who are hospitalized are diagnosed or treated with nuclear medicine techniques. This text provides a succinct overview and detailed set of procedures and considerations for patient therapy with unsealed radioactivity sources. Serving as a complete literature reference for therapy with every radiopharmaceutical currently utilized in practice, this source covers the quality control of radiopharmaceuticals, the role of the physician in radionuclide therapy, and essential procedures and protocols required by health care personnel.

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Oxford Handbook of Accident and Emergency Medicine, 2nd Edition

2011-02-26T01:40:00.001-08:00

Oxford Handbook of Accident and Emergency Medicine, 2nd Edition

Book Detail
Publisher: Oxford University Press, USA;
Publishing Date: May 19, 2005
Number of Pages: 600 pages
Language: English
ISBN-10: 0198526237
ISBN-13: 978-0198526230
Format: CHM
File Size: 11.8MB

Book Intro
Description:This popular Handbook provides practical, accessible guidelines on a huge range of situations that present to the A & E department, and is the essential guide for junior doctors (including candidates for examinations in Accident and Emergency Medicine), specialist nurses, paramedics, and general practitioners. The text is deliberately precise and prescriptive. It gives up-to-date step-by step advice on presentation, investigation, diagnosis, emergency treatment and further referral for adult and pediatric patients, important practical procedures are covered in stepwise, easy-to-follow format with line diagrams illustrating anatomical landmarks.

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Targeted Radionuclide Tumor Therapy: Biological Aspects

2011-02-25T03:06:00.000-08:00

Targeted Radionuclide Tumor Therapy: Biological Aspects

Book Detail
Publisher: Springer
Language: English
ISBN:1402086954
Number of Pages: 402 pages
Year: 2007
Format: PDF
File Size: 5 Mb

Book Intro
The last three decades have provided opportunities to explore the potential of treating malignant diseases with antibodies or other targeting molecules labelled with nuclides. The expanding array of new targeting molecules (recombinant antibodies or peptides) may increase the therapeutic efficacy. The title of this book "Targeted Radionuclide Tumor Therapy – Biological aspects" was selected to reinforce the concept that a major focus was devoted to understanding the biological effects of targeting and radiation. Furthermore, our rapidly expanding knowledge of low dose-rate effects, different types of cell death, autosensitization and the increasingly likely existence of cancer stem cells suggests to us that even more efficient approaches in targeting might be possible in the future.The development of targeted therapy is a true multidisciplinary enterprise involving physician scientists from the fields of nuclear medicine, radiation therapy, diagnostic radiology, surgery, gynaecology, pathology and medical oncology/haematology. It also involves many preclinical scientists working with experimental animal models, immunochemistry, recombinant antibody technologies, radiochemistry, radiation physics and basic cell biology.It is the ambition of the editors to enable deeper insights in the process of improving targeted therapy. We believe that the time now has come when targeted therapy can soon be added to standard oncology treatment regimens.

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Radionuclide Peptide Cancer Therapy (2006)

2011-02-25T02:03:00.000-08:00

Radionuclide Peptide Cancer Therapy

Book Detail
Publisher: Informa HealthCare English
ISBN: 0824728874
Number of Pages: 376 pages
Year: 2006
Format: PDF
File Size: 4 Mb

Book Intro
Description: Offering lower toxicity and higher accuracy than conventional therapies, this source offers illustrative coverage of this new method to treat tumors associated with brain, breast, lung, and neuroendocrine cancers. Accompanied by a CD offering color images, radiolabeling procedures, and tips on radiopharmceutical administration, this source will offer comprehensive and expert guidance on this burgeoning therapeutic technique.

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Fundamentals of Nuclear Pharmacy, 6th edition

2011-02-24T08:04:00.000-08:00

Gopal B. Saha, "Fundamentals of Nuclear Pharmacy" 6th edition

Book Detail

Publisher: Springer

Number of Pages: 410 Pages

Year: 2010

ISBN: 1441958592

Format: PDF

File Size: 8.06 Mb

Book Intro

Established as a classic text on nuclear chemistry and pharmacy, Fundamentals of Nuclear Pharmacy has been thoroughly revised with new information added covering innovations in imaging technology and clinical applications in the field. The Sixth Edition also eliminates outdated information from previous editions on radiopharmaceuticals now discontinued from the market. Dr. Gopal B. Saha??™s books have continually been praised for their clarity and accuracy while setting new standards for making complex theoretical concepts readily understandable to the reader. Like past editions, this book is intended to be used as a textbook on nuclear chemistry and pharmacy for nuclear medicine residents and students and as a reference book for nuclear medicine physicians and radiologists. New sections in the Sixth Edition include: ??? PET/CT and SPECT/CT ??? Digital Imaging ??? Exploratory IND ??? Nanoparticle Imaging ??? Treatment of liver cancer with 90Y-TheraSpheres and 90Y-SIR-Spheres ???

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Radiotherapy in Practice: Radioisotope Therapy

2011-02-24T07:59:00.000-08:00

Peter J. Hoskin “Radiotherapy in Practice: Radioisotope Therapy"

Book Detail

Published by Oxford University Press, USA 2007-03-22

ISBN: 0198568428

Number of Pages: 184 pages

Format: CHM

File Size: 5.1 Mb

Book Intro

Radioisotope therapy is an internal form of radiation used to treat cancer; it may be administered orally or intravenously and represents the nearest treatment option to the 'magic bullet', specifically targeting sites of disease whilst sparing surrounding normal tissues. Radioisotope therapy has an important role to play in modern medicine, particularly in the treatment of thyroid disease, neuroendocrine tumours, bone metastasis and non-Hodgkin's lymphoma. It is found in both the diagnostic setting and in therapy, but recently there has been a renaissance in the application of radioisotope unsealed sources in therapeutic indications. It is an active area of research, with the quest for new compounds that will be specific for therapeutic targets. This book is an essential, practical guide to the use of radioisotope therapy, and also includes the background and developmental biology which underpins its use. Individual tumours and diseases are explored, with specific focus given to radioisotope treatment options. The barriers to radioisotope therapy, such as ease of access, acquisition of radioisotopes, radiation protection regulations, and cost are also discussed. ABOUT THE SERIES Radiotherapy remains the major non-surgical treatment modality for the management of malignant disease, with over 50% of patients receiving treatment at some time during the management of their malignant disease. It is based on the application of the principles of applied physics, radiobiology, and tumour biology to clinical practice. Each volume in this series takes the reader through the basic principles of different types of radiotherapy, and then develops these by individual sites. This series of practical handbooks are aimed at physicians both training and practising in radiotherapy, as well as medical physicists, dosimetrists, radiographers and senior nurses.

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Graham L. Patrick - An Introduction to Medicinal Chemistry, 4th Edition

2011-02-21T08:42:00.000-08:00

Graham L. Patrick - An Introduction to Medicinal Chemistry, 4th Edition

Book Detail

Published by Oxford University Press 2009

ISBN: 0199234477

Number of Pages: 752

Format: DJVU

File Size: 21.2 MB

Book Intro

The average person in the UK will take more than 14,000 pills over the course of their life, yet few people consider the long road of development that has made that drug work without being toxic. An Introduction to Medicinal Chemistry presents the field in an engaging style that is very accessible to students.
Medicinal chemistry is a fast-moving field whose continuous new developments have far-reaching implications for world health. As such, this text presents a complete course in medicinal chemistry, from first principles of drug action, to design and development, to specific drugs from HIV inhibitors to painkillers.
The book builds on the history of drug development, but does not assume much background knowledge. The focus is on building upon the understandings of the molecular function of drugs, and from there, taking a broad overview of the topical issues and most frequently used techniques.
An Introduction to Medicinal Chemistry remains a leading text for the growing number of medicinal chemistry courses internationally, especially as modules in medical chemistry become a more popular option on chemistry courses. With enhanced attention to the pedagogical details such as key points and boxes, as well as having specific case studies highlighted in distinct sections, Patrick's new edition enables a full understanding of the subject and a clear idea of where the field is heading.

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Burger's Medicinal Chemistry and Drug Discovery, 6 Volume Set, 6th Edition

2011-02-21T08:18:00.000-08:00

Book Detail

This new sixth edition of Burgers Medicinal Chemistry and Drug Discovery offers several new and unique features. For the first time, all volumes are structured entirely according to content and published simultaneously to provide broad coverage of medicinal chemistry and drug discovery for new or experienced medicinal chemists, biologists, pharmacologists and molecular biologists. This includes a current and global perspective of drug design, and drug development.

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Respiratory Medicine: An Asian Pespective

2010-09-16T12:12:00.000-07:00

Respiratory Medicine: An Asian Pespective

By Mary Ip, Moria Chan-Yeung, Wah Kit Lam, Nan Shan Zhong

Book Detail

Publisher: University of Washington Press
Number Of Pages: 513
Publication Date: 2005-01-31
ISBN-10 / ASIN: 962209693X
ISBN-13 / EAN: 9789622096936

Book Intro

This book is the first of its kind to focus on respiratory health and diseases in Asia. It is well known that disease patterns and health care delivery vary in different parts of the world. With divergent socioeconomic background, genetic makeup and environmental factors, health care issues take on a different perspective in Asia compared to other places in the world.

The chapters are contributed by professional leaders who are highly respected for their clinical expertise in respiratory medicine in different parts of Asia. Many of them are internationally renowned for their academic excellence. This book is a useful reference for medical students, clinicians in training and respiratory specialists

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Pharmacy Case Studies

2010-09-16T11:16:00.000-07:00

Pharmacy Case Studies

By Soraya Dhillon, Rebekah Raymond

Book Detail

Publisher: Pharmaceutical Press
Number Of Pages: 458
Publication Date: 2009-02-28
ISBN-10 / ASIN: 0853697248
ISBN-13 / EAN: 9780853697244

Book Intro

Whilst most pharmacy undergraduate texts are subject specific, "Pharmacy Case Studies" encourages students to take an integral approach to pharmacy via a series of pharmacy cases. Knowledge gained within the individual areas of law and ethics, pharmaceutics, pharmacology and pathology are tested by each example, bringing together all areas taught on the degree course. Each chapter contains five case studies, starting with uncomplicated cases and increasing in complexity as they expand

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