Anything Goes!

Instagram GRIDS for imac

2022-08-10T19:58:00.001-07:00

I have this new software I am very impressed with it allows me to do certain kinds of searches in instagram I couldn’t normally do and meet my neighbors and such it is really awesome, I like living out in the rural country it’s a little bit better than living in the city.

Okay I am testing a new software to use

2022-08-10T17:25:00.001-07:00

Basically I am using a blogging software and I could like to see it embedded in an email lets see how this goes.

WSSU is using a new app for their classroom scheduling management

2022-08-09T14:11:00.001-07:00

There is this new app called canvas when I was an undergraduate it was moreso a positive change rather than blackboard.

Blackboard was cumbersome, I am happy about this new software, it connected to my mobile device as well through QR code.

it looks like a meaningful productivity app, they are concerned that someone else could take my exams, I find it hilarious. These are not undergraduate exams I doubt any non discipline people could pass these exams seriously...

I got a new Apple computer MacBook Air M2

2022-08-08T23:24:00.001-07:00

I am very pleased today, I have been able to get a Macintosh computer I have been waiting for about 2.5 weeks for it to come in, and I am very pleased with the availability of software if you get creative with it. I got a discount for the Macintosh through the educational discount which gives me a $150 gift card which makes the Apple worth buying because there is all kinds of software that makes it worth buying. Let me add a photo.

MacBook Air M2

I was able to purchase this blogging software which could possibly make it easier for me to update my blog, and I have tried other websites such as that Japanese website ameoba but honestly a Blog is a centralized location to make self-notes and discuss issues.

I cannot go to town without being looted!

2022-01-14T23:04:00.000-08:00

Every time I go to the city to McDonald's, or Hardees everyone thinks I am rich for some reason. I am having internal heart struggles about Charity, because everyone treats me like a walking wallet for some reason. I have lost hundreds of dollars this year alone just from beggars. There is a Christian homeless encampment by my house in Stedman, NC and they sit out there with their offering cup and I try to pass something, but the proactive panhandlers are winning the earnings game by soliciting for money.

Also people camp out the ATM's trying to get cash from other people. Whores do in in Reno also they will grab the guys asses and shit. Women panhandlers are no different than men panhandlers. Why is scamming and panhandling the primary ways of making money nowadays? Why is it that homeless people are attracted to cities so much and the cities refuse to enforce laws about camping outside? I am sick and tired of the ACLU saying that people have the freedom to sleep on the city streets and turn it into a pile of human filth. This problem is getting out of control.

My opinions about E-commerce

2020-04-15T02:51:00.001-07:00

This is why e-commerce is so difficult because making a powerful e-commerce website costs so much money in advanced cybersecurity and it costs so much money to train and hire cybersecurity people, that it's better for things to be funneled into very good website stores. (Walmart/Amazon/etc,). I suggest less wifi, better security practices in corporations and remember that cybersecurity can run up to huge budgets very quickly. The nation needs to adapt to cybersecurity practices because it's easier to hack than be secure.

food disributing is working well also through the grocery store chains (Lowe's/Food Lion) online. Electronics has 5-8 websites, but still every single security officer is worth minimum of 60-80k and it's rare skill that is difficult to increase supply and the workforce is rather political.

Small businesses are literally being a cripple by not following amazon's/Walmart retailer policies also, and I have rejected businesses that have had their Amazon accounts shut down.

Amazon right now has too much power over the economy representing 60% of all e-commerce there needs to be a judicial commerce court just for amazon deciding that they are a private company that has dictator powers over people's accounts.

The difference between auto quotes and amazon. Is that auto quotes supports small business fixtures and general stores by increasing their product inventory), Amazon is a "kill all" model that put everyone out of business when he moved out of books. The cellphone business is nice, but I would appreciate him partnering with small business stores more and not being such a commercial dominator. I use amazon when I am really busy working and I need a tool basically I am a prime member.

If you government employees ever wanted to heal this country is to buy into autoquotes and have an "ethical" e-commerce business strategy with de-centralized business.

My opinion about the pope saying "Thou Shalt not Frack"

2020-04-11T08:03:00.003-07:00

Pope Francis is saying that "Thou Shalt not Frack", the problem with drilling is they accuse people of poisoning the water. When the Ensign United States Drilling + Halliburton makes a hole, they make a pilot hole first to determine the layers of sediment in the earth. Once the sediment tables are determined, then about 150 directional holes are drilling (about 4 holes per pad) in an area. The casing is a huge tube of steel that is put into the ground below the water table, it takes about 4-6 hours for the 2 crews to lay in the casing, then cement is poured on the outside of the pipe, that keeps the pipe solid and linked together.

That corporation rode me harder than any other work out there, they almost broke me down every day I almost collapsed from exhaustion every day after work.

Once the casing is in the ground, the drilling continues to 7000-1000ft, and then once the 4 holes are drilled with direction tools in different directions to cover more square area. once the drilling rig work is complete, a "workover" rig comes out there, and lays a perforated pipe into the ground, that allows the gas to collect from the pipe. I personally am not sure about the fluids injected at 7000-10000ft because it is a closely guarded industrial secret from Halliburton, but I am sure that it is so deep that it does not come into contact with the water supply, and if done properly with American technology, it is safe for hte people who live off of well water.

China vs. US conflict over Taiwan/Formosa Strait

2020-04-07T17:55:00.000-07:00

This is an almost 100-year conflict, which made a lot of sense when there was so much currency difference between the mercantile British and the Imperial American government who both had powerful navies to secure Taiwan's independence. The Taiwanese government has failed in a land invasion with standard firearms or any kind of beach landing already.

The militarization and modernization of the Chinese army are going to give them dangerous military capabilities in which in a war similar to all the others, which has lacked public support over these imperial wars. Dissidence over the imperial American wars has gone back to 1899 with Mark Twain's protesting the Philippine invasions, which was a waste of time and money, and colonization of the Philippines.

It is possible to defeat China in a major conflict by knocking out the industrial factories producing the components for war machines and such, however, it is a lot easier for the United States to retreat to Guam/Hawaii at this point to continue to dominate in naval wars if necessary, and not bother on land invasions because they are so much more expensive. Wars over the horizon are the normal now and it is much easier to fight on the ocean.

The USA can engineer materials overtime to raise the distance of aircraft to 7,000-10,000 miles to round trip into the heart of China to hit mapped outbuildings. However a land war is costly, so the only thing that can be achieved is disarmament and deterrence of China. Any real war with China the current voting population of Taiwan who supports non-reunification is ~5,000,000 and this is not nearly the number needed to defeat the PRC and they do not reproduce population fast enough because of the inequality of the capitalist system causes polygamy and lack of population growth, to fight in a future war.

A good option in this situation is any of these 5,000,000 people who are unwilling to live under Chinese rule should be allowed to immigrate to America and just empty out the Island, and allow the Island to lose its economic productivity as a cheaper and safer alternative the USA could import a major "Tiger" and gain this GDP in the SW or NW or even BC, Canada. The pacific ocean is a powerful deterrent on its own and the USA owns the pacific ocean and it's very difficult to fight the USA to Hawaii. Consider my suggestions.

2018-04-29T18:37:00.001-07:00

Overview of Silver Nanowires

Aaron Linder

1. Introduction

Silver Nanowires are some of the most modern materials being available on the market. There is many recent publications and academic research about Silver Nanowires and what is the methods of fabrication, synthesis, and what are the properties of these nanowires. This paper will attempt to make a summary of Silver Nanowires various topics in a short summary.

2. Properties of Silver Nanowires

a. Mechanical Properties of Silver Nanowires

In recent years nanowires, have attracted significant interest because of their superior mechanical properties [5]. Silver Nanowires Grown in the á1 1 2ñ direction have been shown to have significantly increased yield strength compared to Ag bulk. Size dependent Young’s Moduli have been reported for FCC metals, both in simulation and experimental studies. [1-4]

b. Electrical Properties of Silver Nanowires

Silver is considered a 1-d nanomaterial so it experiences Ballistic Transport. Ballistic transport means that the nanowire has negligible electrical resistivity caused by scattering. Without scattering, electrons simply obey newtons second law of motion at non-relativistic speeds. There is only a base resistance once the electrons reach their target of a larger substrate to connect to. This is the basic resistivity of the quantum-mechanical contact resistance, there are other sources of contact resistance, such that as produced of poor coupling between the mesoscopic conductor and the leads. Ballistic conduction occurs when the length of the conductor is smaller than the mean free path of the electron [6]. The lack of impurities that cause elastic scattering in the conduit material is imperative for this to occur; loss of quantization results if this happens.

c. Optical Properties of Silver Nanowires

Silver nanowires and silver-nanowire thin films have attracted much attention due to their extensive applications in Surface-Enhanced Raman Scattering (SERS) and Surface-Enhanced Fluorescence (SEF). [7] Silver nanowires are one of the most extensively studied metal nanostructures for applications in nanoelectronics and nanodevices, due to their novel optical and physical properties, such as dual plasmon resonance bands, strong SERS and SEF activity. [8-11] Plasmonics refers to the study of enhanced electromagnetic properties of metallic nanostructures. The term is derived from plasmons, the quanta associated with longitudinal waves propagating in matter through the collective motion of large numbers of electrons. [8]

Silver Nanowires can be used with other ions and nanoparticles attached to have enhanced fluorescence. High enhancement of fluorescence emission, improved fluorophore photostability, and significant reduction of fluorescence lifetimes have been obtained from high aspect ratio (>100) silver (Ag) nanowires. These quantities are found to depend on the surface loading of Ag nanowires on glass slides, where the enhancement of fluorescence emission increases with the density of nanowires. The surface loading dependence was attributed to the creation of intense electric fields around the network of Ag nanowires and to the coupling of fluorophore excited states that takes place efficiently at 10 nm from the surface of nanowires, which was confirmed by theoretical calculations. [12]

3. Fabrication of Silver Nanowires

a. Polyol Synthesis of Silver Nanowires

One of the methods used to synthesize Silver nanowires is the polyol process. There are many different variables to take into consideration when doing polyol synthesis. The variables are the temperature, injection ate, molar ratio of the precursor poly(vinylpyrrolidone) to silver nitrate, sodium chloride amount, and stirring rate. [14] The reagents to create Silver Nanowires using Polyol Synthesis is Ethylene glycol (>99.0%, J. T. Baker), AgNO₃ (99+%, Aldrich), polyvinylpyrrolidone (PVP, MW ≈ 55000, Aldrich), glycolaldehyde dimer (Aldrich), concentrated nitric acid (70% reagent grade, Aldrich),

concentrated hydrochloric acid (37% reagent grade, Aldrich), and acetone (reagent grade, Aldrich).[13]

The chemical kinetics can be mapped out and plotted to reach ideal diameter nanowires but that is not within the scope of this text. This is a reliable method of making nanowires using self-assembly and heterogenous nucleation.

b. Nano-Imprint and E-beam Evaporation

Nano-Imprinting via self-assembly is a popular method of fabricating silver nanowires, afterwards E-beam is used to evaporate the silicon. This method of polymer stamping is very good because it can more accurately control the diameter of the Silver nanowires from a stamp. The only limitation is the wavelength of UV-light which can get down to 15 nm. Most nanowires desired length and diameter are much larger for their optical and mechanical properties to be tuned to the correct size.

This method is an efficient method of producing highly uniform nanowires that is relatively inexpensive compared to etching. According to Feng “Over the past 60 years, numerous techniques have been developed to fabricate nanostructure

arrays, including electron-beam lithography (EBL), chemical vapor deposition (CVD), hydrothermal growth, reactive inkjet printing (RIJ), and

template-assisted synthesis. The EBL and CVD methods are limited by their expensive and time-consuming processes.”[18] This method appears to be one of the most efficient methods overall of producing Silver Nanowires.

c. Electrochemical deposition

Although CVD is classically thought to be one of the worst methods of creating silver nanowires, a variation method has been tested using electrochemical deposition. In a Nature 2016 paper a method for digitally controlled, optically induced electrochemical deposition was journaled. Projected light patterns were used to induce an electrochemical reaction in a specialized sandwich-like microfluidic device composed of one indium tin oxide (ITO) glass electrode and an optically sensitive-layer-covered ITO electrode. Silver polyhedral nanoparticles, triangular and hexagonal nanoplates, and nanobelts were controllably synthesized in specific positions at which projected light was illuminated. The silver nanobelts had rectangular cross-sections with an average width of 300 nm and an average thickness of 100 nm. By controlling the applied voltage, frequency, and time, different silver nanostructure morphologies were obtained.[18]

d. Hydrothermal Growth

Much effort has been devoted to the syntheses of silver nanowires, such as electrochemical techniques, templates, and carbon nanotubes, directed synthesis, and polymer-directed synthesis. Recently, Murphy and co-workers have reported a seedless and surfactantless wet chemical approach to prepare silver nanowires. Uniform silver nanowires with diameters of about 100 nm and lengths up to 500 mm were successfully prepared on a large scale through a simple hydrothermal process without the use of any surfactants or polymers. [19]

e. Reactive inkjet Printing

The production of low-cost electronic devices will be revolutionized by the ability to print functional materials. Printed electronics involves the additive fabrication of devices on substrates and over large areas at relatively low temperatures. One of the simplest methods is inkjet printing, a non-contact, additive process which can deposit droplets of ink on a substrate in predefined patterns. Conversely, metallic nanowires, most commonly found as silver nanowires (AgNWs), have recently demonstrated huge potential in transparent electrode applications. Highly conductive silver nanowire electrodes can be fabricated at low temperature and over large areas and are extremely flexible. They have demonstrated sheet resistances as low as 5 Ω/□ for transparencies of 90%. However, while many methods for the deposition of metallic nanowires have been investigated, direct writing of patterned, high-quality silver nanowire networks has proven extremely difficult. To the best of the our knowledge, very few papers have described direct writing of metallic nanowire traces, in this case using inkjet printing.[20] Of the papers that do exist, only one describes the printing of AgNWs in any detail.[21]

4. Uses of Silver Nanowires

a. Thin Films

One use of Silver Nanowires is to create organic solar cells. Using core-shell nanowires, silver electrodes can be created. I am not sure about the details of the construction of solar panel parts. Organic photovoltaics (OPVs) are considered as a future alternative for conventional silicon based solar cells, owing to their low cost, ease of production and high-throughput. The transparent conducting electrode (TCE) is a fundamental component of OPVs. Traditionally, indium tin oxide (ITO) has been mainly utilized as a TCE in OPV applications due to its relatively high transparency and low sheet resistance. However, increasing demand for the optoelectronic devices has led to large fluctuations in ITO prices in the past decade and ITO is known to account more than 50% of the total cost of OPV devices. Thus, it is believed that development of solution-processable alternative materials is of great importance in reducing the cost of OPVs. Silver nanowires have been proposed as a replacement for ITO films in solar cells. [22]

b. Sensors

Silver Nanowires can be used as biosensors, not only because of their surface plasmonics being sensitive to biomolecules, but also as glucose sensors. [23] Integrated sensors for sensing bodily measurements can be used also. [24] Silver nanowire (AgNW) films are particularly promising because they can be fabricated economically from a readily available abundant metal and are flexible enough to enable larger screens or even electronic newspapers in the future. Now researchers from the Universities of Surrey and Sussex have shown that the industrial techniques used to fabricate the sensors in smart phones and tablets could just as easily incorporate AgNWs instead of ITO. [25]

c. Transistors

Thin-film field-effect transistor is a fundamental component behind various modern electronics. The development of stretchable electronics poses fundamental challenges in developing new electronic materials for stretchable thin-film transistors that are mechanically compliant and solution processable. Wearable and biomedical electronic applications demand advanced materials and electronic devices to simultaneously possess deformability, solid state, light weight, visual transparency and low processing cost. Stretchable thin-film field-effect transistor (TFT) would become a fundamental building component enabling a variety of stretchable electronic devices including displays, sensor arrays, thin-film circuits and identification tags for control, data-processing and communication. It has been recently reported intrinsically stretchable solid-state organic light-emitting devices (OLED) and simple pixelated displays. [26,27,28]

5. Bibliography

[1] F. Ma, K.W. Xu

Mater. Res., 21 (2006), p. 2810

CrossRef View Record in Scopus

[2]

M.T. McDowell, A.M. Leach, K. Gall

Nano. Lett., 8 (2008), p. 3613

CrossRef View Record in Scopus

[3]

J.R. Greer, J.T.M. De Hosson

Prog. Mater. Sci., 56 (2011), p. 654

Article Download PDF View Record in Scopus

[4]

Y. Zhu, Q. Qin, F. Xu, F. Fan, Y. Ding, T. Zhang, B.J. Wiley, Z.L. Wang

Phys. Rev. B, 85 (2012), p. 045443

CrossRef

[5] Kobler, A., Beuth, T., Klöffel, T., Prang, R., Moosmann, M., Scherer, T., … Bitzek, E. (2015). Nanotwinned silver nanowires: Structure and mechanical properties. Acta Materialia, 92, 299–308. https://doi.org/10.1016/j.actamat.2015.02.041

[6] G. Cao, Nanostructures & nanomaterials: Synthesis, properties & applications, Imperial college Press, London (2004)

[7] Luu, Q., Doorn, J., Berry, M., Jiang, C., Lin, C., & May, P. (2011). Preparation and optical properties of silver nanowires and silver-nanowire thin films. Journal of Colloid and Interface Science, 356(1), 151-158. doi:10.1016/j.jcis.2010.12.077

[8] T. Vo-Dinh, A. Dhawan, S.J. Norton, C.G. Khoury, H.N. Wang, V. Misra, M.D. Gerhold

J. Phys. Chem. C, 114 (16) (2010), pp. 7480-7488

CrossRef View Record in Scopus

[9]

E. Galopin, J. Barbillat, Y. Coffinier, S. Szunerits, G. Patriarche, R. Boukherroub

ACS Appl. Mater. Interface, 1 (7) (2009), pp. 1396-1403

CrossRef View Record in Scopus

[10]

S.J. Lee, Z.Q. Guan, H.X. Xu, M. Moskovits

J. Phys. Chem. C, 111 (49) (2007), pp. 17985-17988

CrossRef View Record in Scopus

[11]

S.J. Zhuo, M.W. Shao, L.A. Cheng, R.H. Que, D.D.D. Ma, S.T. Lee

J. Appl. Phys., 108 (3) (2010), p. 034305

CrossRef

[12] Abel, B., Coskun, S., Mohammed, M., Williams, R., Unalan, H. E., & Aslan, K. (2015). Metal-Enhanced Fluorescence from Silver Nanowires with High Aspect Ratio on Glass Slides for Biosensing Applications. The Journal of Physical Chemistry. C, Nanomaterials and Interfaces, 119(1), 675–684. http://doi.org.ncat.idm.oclc.org/10.1021/jp509040f

[13] Schuette, W. M., & Buhro, W. E. (2014). Polyol Synthesis of Silver Nanowires by Heterogeneous Nucleation; Mechanistic Aspects Influencing Nanowire Diameter and Length. Chemistry of Materials, 26(22), 6410–6417. https://doi.org/10.1021/cm502827b

[14] Coskun, S., Aksoy, B., & Unalan, H. E. (2011). Polyol Synthesis of Silver Nanowires: An Extensive Parametric Study. Crystal Growth & Design, 11(11), 4963–4969. https://doi.org/10.1021/cg200874g

[15]

N.C. Bigall, B. Nandan, E.B. Gowd, A. Horechyy, A. EychmüllerHigh-resolution metal nanopatterning by means of switchable block copolymer templates

ACS Appl. Mater. Interfaces, 7 (2015), pp. 12559-12569

CrossRef View Record in Scopus

[16]

T. Jang, S. Kim, H. Jung, J. Chung, H. Kim, Y. Koh, J. SongLarge-scale nanopatterning of metal surfaces by target-ion induced plasma sputtering (TIPS)

RSC Adv., 6 (2016), pp. 23702-23708

CrossRef View Record in Scopus

[17]

Erb, Denise. Nanopatterning via self-assembly: Highly ordered metal nanostructures on diblock copolymer templates. IKS institute seminar. No. DESY-2013-00812. DOOR-User, (2013).

[18] Feng, Yuyi. “Silver Nanowire Arrays: Fabrication and Applications.” University Konstanz, 2016, webcache.googleusercontent.com/search?q=cache:HCYsZ7GmVLUJ:https://kops.uni-konstanz.de/bitstream/handle/123456789/38932/Feng_0-406729.pdf%3Fsequence%3D3+&cd=4&hl=en&ct=clnk&gl=us.

[18] Li, P., Liu, N., Yu, H., Wang, F., Liu, L., Lee, G.-B., … Li, W. J. (2016). Silver nanostructures synthesis via optically induced electrochemical deposition. Scientific Reports, 6, 28035.

[19] K. K. Caswell, C. M. Bender, C. J. Murphy, Nano Lett. 2003, 3, 6 6 7– 669.

[20] Finn, D. J., Lotya, M., & Coleman, J. N. (2015). Inkjet Printing of Silver Nanowire Networks. ACS Applied Materials & Interfaces, 7(17), 9254–9261. https://doi.org/10.1021/acsami.5b01875

[21] Wu, J.-T.; Hsu, S. L.-C.; Tsai, M.-H.; Liu, Y.-F.; Hwang, W.-S. Direct Ink-Jet Printing of Silver Nitrate-Silver Nanowire Hybrid Inks To Fabricate Silver Conductive Lines J. Mater. Chem. 2012, 22, 15599–15605

[Crossref], [CAS]

[22] Basarir, F., Irani, F. S., Kosemen, A., Camic, B. T., Oytun, F., Tunaboylu, B., … Choi, H. (2017). Recent progresses on solution-processed silver nanowire based transparent conducting electrodes for organic solar cells. Materials Today Chemistry, 3, 60–72. https://doi.org/10.1016/j.mtchem.2017.02.001

[23] Wang, L., Gao, X., Jin, L., Wu, Q., Chen, Z., & Lin, X. (2013). Amperometric glucose biosensor based on silver nanowires and glucose oxidase. Sensors and Actuators B: Chemical, 176, 9–14. https://doi.org/10.1016/j.snb.2012.08.077

[24] Boland, C. S., Khan, U., Benameur, H., & Coleman, J. N. (2017). Surface coatings of silver nanowires lead to effective, high conductivity, high-strain, ultrathin sensors. Nanoscale, 9(46), 18507–18515. https://doi.org/10.1039/C7NR06685F

[25] Cann, M., Large, M. J., Henley, S. J., Milne, D., Sato, T., Chan, H., … Dalton, A. B. (2016). High performance transparent multi-touch sensors based on silver nanowires. Materials Today Communications, 7, 42–50. https://doi.org/10.1016/j.mtcomm.2016.03.005

[26]
Yu, Z., Niu, X., Liu, Z. & Pei, Q. Intrinsically stretchable polymer light-emitting devices using carbon nanotube-polymer composite electrodes. Adv. Mater. 23, 3989–3994 (2011).

[27] Liang, J. et al. Silver nanowire percolation network soldered with graphene oxide at room temperature and its application for fully stretchable polymer light-emitting diodes. ACS Nano 8, 1590–1600 (2014).

[28] Liang, J., Li, L., Niu, X., Yu, Z. & Pei, Q. Elastomeric polymer light-emitting devices and displays. Nat. Photonics 7, 817–824 (2013).

A quick description of New Cancer detection, tumor fighting, and metastatic fighting cancer cures.

2018-04-21T14:07:00.002-07:00

There are several techniques recently developed that allow for the detection, selective cell-destroying, and eventually, cure for Metastasis in early trials in the last 5 years. These are breakthrough technologies, if released to the public, could greatly lengthen human lifespans.

The first technology that will be discussed is the ability to screen for cancer. Imaging techniques of in-vivo tumors have several techniques. This fluophore in the first paper discussed is a targetable “activatable” fluophore that can be controlled to only fluoresce when a current target molecule: “fluorophores could be controlled and predicted precisely by using the concept of intramolecular photoinduced electron transfer”[1]. Several fluophores were created DPAX and DMAX for singlet oxygen, DAF, DAMBO and DACals for nitric oxide. HPF, APF and APC for highly reactive oxygen, NiSPYs for peroxynitrite, DNAT-Me for glutathione S-transferase, TG-BetalGal for Beta-galactosidase and some more.

These fluophores are specifically targeted for specific ions and compounds known in cancer cells. The reactions of each to determine which fluophore for which molecule is beyond my skill in metallo-organic chemistry. Here is the table.

In-vivo cancer visualization is created by making targeted activatable fluorescent imagine probes. Novel acidic pH-activatable probes based on the BODIPY fluophore were developed using the PeT – based rational design strategies, and conjugated them to a cancer-targeting monoclonal antibody. This agent is activated after endocytotic internalization by sensing the pH change in the lysosome. Here is a chart of the functioning of the fluorescence dye.

This reaction occurs within 1 minute after being applied. Tiny tumors less than 1 mm size were successfully detected based on the concept of signal activation by using cancer-specific antibodies labeled with acidic-pH activatable fluorescence probes.

After the cancer is detected there is a lot of research into which drugs to use to kill the cancer. A programmed drug-delivery system that can transport different anticancer therapeutics to their distinct targets holds vast promise for cancer treatment. Herein, a core–shell-based “nanodepot” consisting of a liposomal core and a crosslinked-gel shell (designated Gelipo) is developed for the sequential and site-specific delivery (SSSD) of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) and doxorubicin (Dox). As a small-molecule drug intercalating the nuclear DNA, Dox is loaded in the aqueous core of the liposome, while TRAIL, acting on the death receptor (DR) on the plasma membrane, is encapsulated in the outer shell made of crosslinked hyaluronic acid (HA). The degradation of the HA shell by HAase that is concentrated in the tumor environment results in the rapid extracellular release of TRAIL and subsequent internalization of the liposomes. The parallel activity of TRAIL and Dox show synergistic anticancer efficacy. The half-maximal inhibitory concentration (IC 50 ) of TRAIL and Dox co-loaded Gelipo (TRAIL/Dox-Gelipo) toward human breast cancer (MDA-MB-231) cells is 83 ng mL –1 (Dox concentration), which presents a 5.9-fold increase in the cytotoxicity compared to 569 ng mL –1 of Dox-loaded Gelipo (Dox-Gelipo). Moreover, with the programmed choreography, Gelipo significantly improves the inhibition of the tumor growth in the MDA-MB-231 xenograft tumor animal model.[2]

The conventional chemotherapeutic drugs attack the tumors by interrupting processes or inhibiting substances essential for the replication and proliferation of the tumor cells. For example, co-delivery of doxorubicin (Dox) and paclitaxel (Ptx) by a polymeric nanoparticle could release both drugs simultaneously and efficiently within the cells. The released Ptx inhibits the intracytoplasmic microtubules disassembly that is required for cell proliferation, while Dox intercalates into the nuclear DNA and induced cell apoptosis. For the cancer gene therapy, siRNA for silencing the target genes in cancer cells and pDNA for implanting corrective genetic material into the cells, have been applied to coordinate with small-molecule drugs. A typical example involves a micellar nanocarrier for co-delivery of MDR-1 siRNA and Dox, the released siRNA in the cells downregulates the P-glycoprotein expression to improve the efficacy of Dox in the multi-drug resistant

cancer cells. [2]

Here is the results of the drugs administered to the tumor and the testing of various drugs. [C] In vitro cytotoxicity of TRAIL-Gelipo, Dox-Gelipo and TRAIL/Dox-Gelipo after 30 min

of HAase pre-treatment toward MDA-MB-231 cells for 24 h.

As you can see, the chemical cocktail has a dramatic effect on the tumor after 14 days. A further problem with tumors is the metastatic ability to grow in regions far away from the original tumor. A recent technology was developed at Duke University to combat this. Metastatic spread is the mechanism in more than 90% of cancer deaths, and current chemical options, such as systemic chemotherapy, are often ineffective. This paper is about Synergistic Immuno Photothermal Therapy (SYMPHONY). Immune checkpoint inhibition is a promising immunotherapy that aims to reverse signals from immunosuppressive tumor microenvironment. Programmed death-ligand 1 (PD-L1), a

protein overexpressed by many cancers, contributes to the suppression of the immune system and cancer immune evasion. PD-L1 binds to its receptor, PD-1 found on activated T cells, and inhibits

cytotoxic T-cell function, thus escaping the immune response. To reverse tumor-mediated immunosuppression, therapeutic anti-PD-1/PD-L1 antibodies have been designed to block the PD-L1/PD-1 interaction. nanoparticle (NP)-mediated thermal therapy has recently demonstrated the potential to combine the advantages of precise cancer cell ablation with benefits of mild HT in tumor microenvironments. NPs have a natural propensity to extravasate from the tumor vascular network and accumulate in and around cancer cells due to the enhanced permeability and retention (EPR) effect. Among various types of nanoparticles, gold nanostars (GNS), whose sharp branches create a “lightning rod” effect that dramatically enhances the local electromagnetic (EM) field, are the most effective in converting light into heat for photothermal therapy (PTT). The unique tip-enhanced plasmonics property of GNS can be optimally tuned in the near infrared (NIR) tissue optical window, where photons can travel further in healthy tissue to be ‘captured’ and converted into heat by GNS taken up preferentially in cancer cells. We have investigated the PEGylated GNS bio-distribution in mice as well as GNS uptake at both macroscopic and microscopic scales by using radiolabeling, CT and optical imaging methods. In addition, a recent toxicity study of aptamer-loaded GNS found no signs of acute toxicity.

In this experiment, only 1 tumor was treated, and the other tumor was not. It was found that using the GNS+Laser+Anti-PD-L1 had the only group of mice that survived the cancer at all. It is shown that this cocktail has the only chance of survival in bladder cancer tumors for any mice at all.

Hopefully, these cancer treatments will assist in the future for detecting, treating, and then treating metastatic cancer in the future and can be applied to human use. Unfortunately, even in experiments, the survival rate is not very high at this point for cancer cures, but some chance of survival is better than no chance of survival. It appears that Phototherapy, in addition with chemical cocktails gives the best chance of survival.

[1] Urano, Yasuteru. “Novel Live Imaging Techniques of Cellular Functions and in Vivo Tumors Based on Precise Design of Small Molecule-Based â˜Activatableâ™ Fluorescence Probes.” Current Opinion in Chemical Biology, vol. 16, no. 5-6, 2012, pp. 602–608., doi:10.1016/j.cbpa.2012.10.023.

[2] Jiang, Tianyue, et al. “Gel-Liposome-Mediated Co-Delivery of Anticancer Membrane-Associated Proteins and Small-Molecule Drugs for Enhanced Therapeutic Efficacy.” Advanced Functional Materials, vol. 24, no. 16, 2014, pp. 2295–2304., doi:10.1002/adfm.201303222.

Liu, Yang, et al. “Synergistic Immuno Photothermal Nanotherapy (SYMPHONY) for the Treatment of Unresectable and Metastatic Cancers.” Scientific Reports, vol. 7, no. 1, 2017, doi:10.1038/s41598-017-09116-1.

Econometrics paper (Difficult Subject)

2014-11-16T19:27:00.001-08:00

4.1 Trends in Entrepreneurship

"How has entrepreneurship fared over the same period of time in which unemployment

rates have increased rapidly and the housing market has dropped significantly? Figure 3

displays annual estimates of the monthly entrepreneurship rate from 1996 to 2009. As

noted above the entrepreneurship rate measures the percentage of the adult, nonbusiness

owner population that starts a business each month. It captures all new business owners,

including those who own incorporated or unincorporated business, and those who are

employers or non employers. In 2009, an average of 0.34% of the adult population, or

340 out of 100,000 adults created a new business each month. The business formation

rate increased from 2008 when it was 0.32%. It was the third straight year that the

index increased, resulting in an increase from 0.29% in 2006 to 0.34% in 2009.

The recent increase is the largest over the 14-year sample period. In fact, over the period from 1996
to 2009, the business creation rate fluctuated within the range of 0.27–0.31%. It was not
until 2008 and 2009 that it rose above the high end of this range, which coincides with the
recent recession. In the late 1990s, the entrepreneurship rate decreased slightly, then rose
from 2001 to 2003. It remained relative constant over the next 3 years before increasing
in the recent recession."[7]

"Another interesting finding is that home owners are more likely to start businesses.

The coefficient is positive and statistically significant, although relatively small. Home

owners have a 0.012 percentage point higher rate of entrepreneurship than non home

owners, which is roughly a 4% higher rate relative to the mean. In the presence of

liquidity constraints, the ability of owners to borrow against the value of their homes,

such as home equity loans, may make it easier to finance new business ventures."[7]

"Figure 4 displays the entrepreneurship rate against the national median home price

in $2009. The negative relationship between the two trends in the recent recession is very

clear. Home prices have dropped sharply over the past few years as entrepreneurship

rates have increased. These patterns run counter to the decline in home equity decreasing

entrepreneurship and are likely due to stronger positive effects of rising unemployment

rates. Entrepreneurship rates also dropped in the late 1990s when home prices were

rising. Interestingly, however, both entrepreneurship and home prices rose steadily in

the early 2000s. In this period, rising home equity may have provided capital for would be-

entrepreneurs to start businesses."[7]

"At the national level, trends in entrepreneurship appear to be primarily counter

cyclical—rising in economic downturns and declining in strong economic growth periods.

The national patterns for entrepreneurship, however, are weaker than unemployment

patterns over the business cycle. Trends in home prices and their effects on access

to capital may have offset some of the business cycle effects. But, these are only broad

strokes based on national trends. Instead, it is important to focus on variation in local

labor market and housing conditions. Unemployment rates and housing prices differ

substantially across metropolitan areas, and these differences can be used to more carefully

examine the relationship between entrepreneurship, and unemployment and home

prices."[7]

"Summary measures of goodness of ﬁt are useful for comparing the performance of different models ﬁt to the same data. Measures include information criteria or R2-type measures. Calculation of these summary measures usually depends on the sample size (or range of data used) and model structure used (such as linear or logistic regression), and so comparisons should only be made between models of the same structure built using the same data. It should be noted that for non-linear models there are multiple different ways to calculate R2-type measures, with no consensus as to which should be used. For non-linear models, goodness-of-ﬁt measures based on the residuals (such as the deviance) or information criteria are preferred. There are sometimes also measures speciﬁc to the model type, such as the Hosmer– Lemeshow test for logistic regression; for further details see Campbell. If Markov Chain Monte Carlo methods have been used, additional properties such as the convergence of the chains, autocorrelation plots, and deviance information criteria should be reported [16]."

"The central puzzle in economic development is to explain what accounts for diﬀerences in output per capita (inequality) across nations. This is what Lucas (1988) posited as the problem of economic development. Based on the neo-classical production function, diﬀerences in output per capita can be attrib-uted to diﬀerences in physical capital, human capital and total factor productivity (TFP). Chari et al. (1997) argue that observed diﬀerences in output per capita can be explained by diﬀerences in factors of production (e.g., physical and human capital). However, Hall and Jones (hereinafter HJ 1999), and Parente and Prescott (1999, 2000) show that the diﬀerence in TFP is the key determinant of diﬀerences in international incomes. Thus, to be able to answer Lucas' question, we must ﬁrst answer the question: What explains international diﬀerences in TFP?[17]

"Recently, considerable attention has been given to the role of institutions in explaining not only diﬀerences in productivity across countries, but also why some countries invest more in physical and human capital (North 1990, Knack and Keefer 1995; Nugent and Robinson 1998; HJ 1999; Parente and Prescott 2000; Acemoglu et al. 2001, Easterly and Levine 2002, among others). By institutions, North (1990) means the formal (laws, constitutions) and informal (customs, traditions) constraints, and government policies (enforcement, punishment) that shape the interactions of economic actors1. For instance, countries with more secure property rights have, in general, higher productivity and therefore higher levels of income per capita. According to North (1990, p.107), institutions ''are the underlying determinant of the long-run performance of economies.''[17]

The output per worker gap among nations, would tend to widen. Quantile regression provides the appropriate tools to determine whether there are different marginal responses of output per worker to changes in institutions. In Fig. 2, we depict the IV estimates (horizontal dashed lines) along with the corresponding quantile regression estimates.

The shaded areas represent 90% confidence intervals; at all estimated quantiles, institutions are statistically and foremost economically significant. As expected, at higher quantiles ðsÞ the return for each additional ''unit'' of institutions decreases relative to lower conditional quantiles of output per worker. Returns vary from approximately 6.2 to 3.8 as s increases. This first difference relative to HJ, as a result of applying the more robust and descriptive methodology of quantile regression, reinforces the importance attributed to institutions in promoting not only development, but also in closing differences in output per worker across nations."

"The state housing collateral ratio is computed using the Lustig and van Nieuwerburgh (2005) method. The unemployment rates are from the BLS. The relative unemployment rate is the ratio of the current unemployment rate to the moving average of the unemployment rates from the previous 16 quarters. Labor income is from the BEA. U.S. cay and U.S. They are downloaded from Sydney Ludvigson's and Stijn van Nieuwerburgh's web sites, respectively.

The three spreads use quarterly data obtained from the Board of Governors of the Federal Reserve System web site. We use 13(f) institutional holdings data from Thomson Reuters to compute the institutional trading variables, while the retail trading variables are computed using retail holdings data from a large U.S. discount brokerage house. The retail data are available only for the 1991 to 1996 period.

The change in local institutional or retail holdings is the percentage change in the value of local holdings (i.e., the total value of shares of ﬁrms headquartered in a state held by investors in the same state). The change in nonlocal institutional or retail holdings is the percentage change in the value of nonlocal holdings (i.e., the total value of shares of ﬁrms headquartered in a state but held by out-of-state investors). To compute the state economic activity index, we add the standardized values of state income growth and state, subtract the standardized value of relative unemployment, and divide this sum by three.

"Low-paid, repetitive positions are most likely to go, with people earning less than £30,000 a year five times more likely to see their jobs taken over by machines than those paid £100,000, new research has warned. Huge advances in technology risks creating an under-class of low-skilled people whose jobs have been automated, according to a joint report from Deloitte, the Big Four accountancy firm, and the University of Oxford.[18]"

Year	Entrepeneurship Rate	Unemployment Rate	Median home price	Entrepeneurship
1996	0.33	0.28	160000	210000
1997	0.27	0.26	165000	185000
1998	0.28	0.24	167000	180000
1999	0.26	0.23	180000	182000
2000	0.27	0.24	182000	183000
2001	0.26	0.23	185000	185000
2002	0.28	0.25	187000	190000
2003	0.29	0.27	205000	210000
2004	0.29	0.26	215000	215000
2005	0.28	0.27	220000	225000
2006	0.27	0.24	240000	185000
2007	0.31	0.24	230000	192000
2008	0.33	0.27	210000	210000
2009	0.34	0.38	185000	225000
2010	0.35	0.4	175000	235000

SUMMARY OUTPUT ENTREPENEURSHIP AND UNEMPLOYMENT

Regression Statistics
Multiple R	0.804484
R Square	0.647195
Adjusted R Square	0.620056
Standard Error	0.018609
Observations	15

ANOVA
	df	SS	MS	F	Significance F
Regression	1	0.008258	0.008258	23.84756	0.000299
Residual	13	0.004502	0.000346
Total	14	0.01276

	Coefficients	Standard Error	t Stat	P-value	Lower 95%	Upper 95%	Lower 95.0%	Upper 95.0%
Intercept	0.165243	0.026801	6.165666	3.4E-05	0.107344	0.223142	0.107344	0.223142
X Variable 1	0.475703	0.097412	4.883397	0.000299	0.265257	0.68615	0.265257	0.68615

SUMMARY OUTPUT MEDIUM HOME PRICE AND ENTRPENEURSHIP

Regression Statistics
Multiple R	0.086584
R Square	0.007497
Adjusted R Square	-0.06885
Standard Error	0.031212
Observations	15

ANOVA
	df	SS	MS	F	Significance F
Regression	1	9.57E-05	9.57E-05	0.098195	0.758977
Residual	13	0.012664	0.000974
Total	14	0.01276

	Coefficients	Standard Error	t Stat	P-value	Lower 95%	Upper 95%	Lower 95.0%	Upper 95.0%
Intercept	0.314501	0.065916	4.771234	0.000365	0.172098	0.456903	0.172098	0.456903
X Variable 1	-1.1E-07	3.38E-07	-0.31336	0.758977	-8.4E-07	6.24E-07	-8.4E-07	6.24E-07

CONCLUSION:

Through many tests of Data analysis, regression, studies of quotations, that has shown through multiple T-Tests, that

Entrepreneurship and unemployment and home prices are correlated through regression, I have not been able to prove that Institutions are increasing Entrepeneurship rates because of lack of Data available, except through graphs available but not data.

ENTREPENEURSHIP_i = .16*UNEMPLOYMENT_i + .32*HOMEPRICE_i +Log(C*INSTITUTIONS(0))+ e_i

(6.16) (4.77)

N=15 R^2=.64

Bibliography:

References

Baharum, A., & Ataharul, M. The analysis of transitions in economic performance using co variate dependent statistical models.Journal of Developing Areas, 43(2), 289-298.
Chien-Chung Nieh, Russel, P. S., Hung, K., & Ya-Kai Chang. The asymmetric impact of financial intermediaries development on economic growth. International Journal of Finance, 21(2), 6035-6069.
Chris Forman, Avi Goldfarb, & Shane Greenstein. The internet and local wages: A puzzle. The American Economic Review, 102(1), 556-575.
De V. Cavalcanti, T. V., & Novo, Á. A. Institutions and economic development: How strong is the relation? Empirical Economics, 30(2), 263-276.
Edelman, B. Using internet data for economic research. Journal of Economic Perspectives, 26(2), 189-206.
Einav, L., & Levin, J. The data revolution and economic analysis. NBER Innovation Policy & the Economy (University of Chicago Press), 14(1), 1-24.
Fairlie, R. W. Entrepreneurship, economic conditions, and the great recession. Journal of Economics & Management Strategy, 22(2), 207-231.
Florens, J., Johannes, J., & Van Bellegem, S. Instrumental regression in partially linear models. Econometrics Journal, 15(2), 304-324.
Kearns, B., Ara, R., Wailoo, A., Manca, A., Alava, M., Abrams, K., et al. Good practice guidelines for the use of statistical regression models in economic evaluations. Pharmacoeconomics, 31(8), 643-652.
KORNIOTIS, G. M., & KUMAR, A. State-level business cycles and local return predictability. Journal of Finance, 68(3), 1037-1096.
Naiana, Ţ., Teodora, V., Cristian, C., & Ioan, Ţ. Study regarding the use of spreadsheet applications in the economic field. Annals of the University of Oradea, Economic Science Series, 19(1), 834-837.
Nelson, N. E., & Germani, P. J. The use of economic data in collective bargaining. Labor Law Journal, 38(11), 715-719.
Rodrigues, J. F. D. A bayesian approach to the balancing of statistical economic data. Entropy, 16(3), 1243-1271.
Rodríguez, F. What can we really learn from growth regressions? Challenge (05775132), 51(4), 55-69.
Webber, D. J., & Mearman, A. Students' perceptions of economics: Identifying demand for further study. Applied Economics, 44(9), 1121-1132.
Cooper NJ, Sutton AJ, Mugford M, Abrams KR. Use of Bayesian Markov Chain Monte Carlo methods to model cost-of-illness data. Med Decision Mak. 2003;23(1):38–53.
North D (1990) Institutions, institutional change, and economic performance. Cambridge University Press, Cambridge.

18. Ten Million Jobs at Risk from Advancing Technology." The Telegraph. Telegraph Media Group, 28 Apr. 0010. Web. 10 Nov. 2014.

A silly prophecy

2014-02-22T22:33:00.002-08:00

One day in 2007 I had a big fight with my girlfriend, she is very unsubmissive and playing power games so I yelled at her on the phone, and we continued to have phone/text/email games until the pressure began to build.

Then one night this strange spirit came to me and I wrote this letter almost sounding like a prophecy about 8 days and the time ending up in 12:00 and speaking of the sun and the moon and the men and the women and who loves who and who was going to win an arguement (I cannot remember my exact language);

Then I walked over to her house and I was thrown in jail.

When I was released I worked on an oil rig for awhile, then I was living with my room-mates, and all these demons rushed me I saw this light point out a demon on the wall as Satan came to me and burned me on fire and I ran back east to my mother's house.

It's been 7 years and now I looked at Matt 24 and my poem was very similar; One month after I got out of jail, Lady Gaga came out with her first album and sang all these songs that all the women listened to, and Barack Obama (the symbol of the moon) was elected for 8 years in a row;

The lord has a better prophecy to be honest:

It's actually coming to pass I think (I have a lot of faith; I just read a report from a physicist of the sun beginning to darken); The state of California declared it's authority as you cannot walk to your girlfriends house when she's angry at you (they will throw you in prison); Therefore if you do, you will go through the sign of Jonas

"

A wicked and adulterous generation seeketh after a sign; and there shall no sign be given unto it, but the sign of the prophet Jonas. And he left them, and departed.

And as he sat upon the mount of Olives, the disciples came unto him privately , saying , Tell us, when shall these things be ? and what shall be the sign of thy coming, and of the end of the world? 4 And Jesus answered and said unto them, Take heed that no man deceive you. 5 For many shall come in my name, saying , I am Christ; and shall deceive many. 6 And ye shall hear of wars and rumours of wars: see that ye be not troubled : for all these things must come to pass , but the end is not yet. 7 For nation shall rise against nation, and kingdom against kingdom: and there shall be famines, and pestilences, and earthquakes, in divers places. 8 All these are the beginning of sorrows. 9 Then shall they deliver you up to be afflicted, and shall kill you: and ye shall be hated of all nations for my name's sake. 10 And then shall many be offended , and shall betray one another, and shall hate one another. 11 And many false prophets shall rise , and shall deceive many. 12 And because iniquity shall abound , the love of many shall wax cold . 13 But he that shall endure unto the end, the same shall be saved . 14 And this gospel of the kingdom shall be preached in all the world for a witness unto all nations; and then shall the end come . 15 When ye therefore shall see the abomination of desolation, spoken of by Daniel the prophet, stand in the holy place, (whoso readeth , let him understand :) 16 Then let them which be in Judaea flee into the mountains: 17 Let him which is on the housetop not come down to take any thing out of his house: 18 Neither let him which is in the field return back to take his clothes. 19 And woe unto them that are with child, and to them that give suck in those days! 20 But pray ye that your flight be not in the winter, neither on the sabbath day: 21 For then shall be great tribulation, such as was not since the beginning of the world to this time, no, nor ever shall be . 22 And except those days should be shortened

Here watch some videos;

A raw unproofed speech for a small credit class. It was decent.

2013-09-03T19:26:00.001-07:00

One habit of a successful student is organization. In our current century, electronic note-taking and organization is a good way to keep information at our fingertips.

Most college students in college will end up having poor grades in school, merely from not organizing themselves and being aware of due dates. Due dates and deadlines are a very important part of school and of real life. We must take as much effort as possible in trying to collect our notes together into a single platform and use task management to be able to sort through our tasks regularly, and stay on top of our responsibilities.

How many people understand that at any given time there may be up to 20-30 tasks at one time to manage and work on in a multi-tasking situation, in which it is necessary to be able to stay on top of project management; as in self management and be able to organize.

In the bible there is a quote which says,"Redeem the time, for the days are evil."

It is very important that we begin to try to redeem our time in productive ways, by organizing our finances, scholarly organization of papers, and making productive time into our assignments by continuing to work on our personal tasks, from day to day, to maintain productivity.

Even being unemployed I would recommend using google calandar/gmail/outlook.

Right now there is many applications available on android, and I can quickly look at my classes on android, and know what my assignments are. I am still struggling currently to try to port over my blackboard onto android, and copy down the syllabus down faithfully, and schedule my time wisely and try to complete my tasks in a timely manner.

Personally I am not a lazy person, I do my best to collaborate and get onto projects and completely them as effectively as possible. However it can be difficult sometimes with information overload or even assignment overload.

In fall 2011, I had a very hard 20 unit semester with Calculus I, Statistics, and Organic Chemistry at the same time, combined with two non-transferable nano science classes, all which required a lot of personal reading and study, and had a huge workload.

I began to quickly see that I was bogged down from the work-load, and recieved two "D"'s that semester because of being overloaded with information and assignments. I was darting around from class to class, trying to remain on top of all my note-books and assignments at the same time, and even then I was not physically capable of doing all my homework and assignments at the same time because of the physical amount of time required to do the work.

I should have dropped classes, but I did not drop I stayed through the entire semester. Once I am capable of integrating all my platforms into a single unified scheduling program, I have seen personal results on task completion and an increase in my GPA, simply from being organized and on top of my assignments and deadlines.

Some people are naturally organized and get exceptional grades and often-times get leadership positions in companies because of their successful leadership abilities. I feel that it is a very good idea to strive to increase our personal leadership and organizational skills by being good communicators with our instructors, and task-masters, and bill collectors, and colleagues in business. Well organized people are capable of getting a lot more work complete and begin to become an asset to an organization.

Franklin Covey has a seminar that people often go to, in the pre-electronic period, businessmen would often use day-planners or steno-pads to organize, however I support online organizers, because I have at times had my electronic devices stolen, and having a cloud computing system available with my notes and assignments and schedule online, can keep myself organized on any device, even a public computer.

In conclusion, perfection of organization is a powerful skill, which can be used to great effect to create one into a successful employee and successful leader in any kind of organization.

bah

2012-12-12T07:50:00.002-08:00

Bah I had opposition today, I had to re-sign up for school since I graduated already to take classes. I missed the early registration, at least I am in sophmore level classes they do not fill up as fast.

Whoot! Back home

2012-12-11T08:32:00.000-08:00

It's been rough not being on a computer since my laptop was stolen. Thankfully my desktop was safe and sound from thieves I can hook it up and still have a computer to work with. Think are looking good today, an apartment is going to be made available for my brother and I (unfortunately the truck was sold), and school signups are tomorrow.

Unfortunately I am not able to transfer to winston-salem state yet, but they are kind enough to get me a fee waiver and get me started on the application process until my expungement hopefully goes through in january.

Today is looking positive!!!

Well I haven't been able to start on that stats paper yet

2012-11-20T08:45:00.001-08:00

Well a few days on the train I'm beginning to feel almost back to normal. Los Angeles didn't treat me so well, all my electronic devices were pilfered and looted. Now I have a phone I am going to have to figure out how to re-establish a device system. I just saw the newest android pad out on the market it's half the price I payed for my old one. But I don't really need one now that I have a phone.

I think at this point I am going to need to worry more about theft than worrying about having a cool tablet or laptop to use. I didn't really need a phone my 7.7 was cost effective and it worked for 9 months, and had a 40 dollar a month cost.

Well I lost 3 changes of rotational clothing and my electronics, but at least I made it out with my wallet and shoes (I was able to drop by the verizon store and got an older android, a 3.2 on my tab). I am kinda pissed off the pad was 500 dollars but I didn't anticipate it getting stolen.

I still have my desktop computer at home, I think at this point I will stay ultra conservative and just stick with the phone and desktop (I will keep my eyes open for a flat screen, if I have to use Photoshop, Mathematica or something I think mobile it's not worth it, I can still read on my phone with little difficulty).

This is why I think the 3d pocket projectors for cellphone will be a hot item on the market, because it's small enough to fit into your pocket to prevent theft but give a large enough screen to see things.

Im not in school right now anyways i don't need my portable computer.

This side pack is nice, I have a charger pack for my cellphone, it helps a lot.

I think for now on i will just use a photographic notepad with one note uploads. I am so dirty I need a shower lol

New urban friend.

2012-11-16T14:06:00.001-08:00

I have a new urban companion haha, I guess I can see the difference between real schizophrenia and my own abnormal psych. He definitely needs to get fish oil and be put into a mentally stimulating environment. Schizophrenia is interesting, the associative property of memory seems to not actually be working correctly, so he speaks about subjects that do not follow logical memory associative properties.

Lol interesting morning

2012-11-13T08:35:00.001-08:00

So I finally met some of the pot smoking hippies with 4 year engineering degrees, high GPA and everything, deciding to be homeless hippies running around collecting welfare simply because they don't want to work. At least if they had some skill as musicians then they could do shows. Occupy wallstreet anarchists are a trip.

Lack of technician positions available =(

2012-11-10T15:45:00.002-08:00

Unfortunately, I have seen a great lack of technician positions in CA and NC so-far. I think it's perhaps because I need to get up to Santa Clara and go to the conferences? Job adds are rarely listed online and they are mostly hired though inside sources.

Jim at the JSNN has been good enough to hire 3/6 graduates at the school, but outside of the state government technicians, the private sector has been unable to actually create the job offerings that the projections have been calling for.

Supposedly according to projections, another 40,000 jobs were supposed to appear in the Triangle/Triad, and more in the Northern California area as well. I have not seen the listings. I might have to continue to look. I think it's about time to email my professor's and see what's going on, and hopefully I can keep my GPA up through these hard years.

Talking to some of the people out here, I think that as long as Obama is president, the government is going to continue to increase school deficit's and school loans, so poeple are going to have to continue getting their degrees higher and higher until the positions become available. I think I have little choice at this point but to continue on the path I've set so-far.

The only positions I've seen so far is senior research scientists, this must mean that either the investors are not giving money for production, or that the post-doctorate researcher positions are so full of post-docs that there is little need for technicians right now, as the science industry in general is taking a big recession.

Hopefully I can to university transfer as this case completes so I can spent this next presidency at college until the economy improves.

I'm tired of panhandling

2012-11-06T10:33:00.001-08:00

JI am starting to have a problem with panhandling. I straight watched this bum make 5 dollars in 10 minutes outside of a fastfood place, and he didn't even go inside to buy food, he was just saving up for beer. There is free food anyways on skid row, there is no excuse to be starving. People don't need to smoke cigarettes, they could get a can of chewing tobacco it could last them all week if their nicotine addiction is so bad.

The market at the corner only took EBT (foodstamps) and cash, I tried to use mastercard and he couldn't take it. I told them to get a square but they didn't even know what it was.

Sigh feet hurt

2012-11-05T12:12:00.001-08:00

I looked at the map the wrong way, until my feet were about to fall off. Hopefully the blisters start to heal. Where is the endorphins?? I finally made my way to the YMCA, definitely better than skid row lol. Finally my dogs were kicking me so I got a city bus ticket. Now I just need to get/ship a pair of tennis shoes down here, get a membership, then most of my day will be fine. a lock too

San Julian Park reminds me of the yard in the penitentiary.

2012-11-04T10:57:00.001-08:00

I don't see any difference between San Julian park and the pen lol. Some psycho~bz sitting next to me jabering nonsense, and a bunch of OG's ( old gangsters sitting there playing pinochle and poker all day long reading old newspapers.
On the way over I happened to hear the worst accordion player in my life. I actually gave him a dollar, while he pathetically tried to play the accordion, while his partner was passed out drunk in the middle of the day; with a bottle of half-drank vodka laying there untouched. He looked as if he was unconscious for a few hours.
There is actually very old laws about swearing and drinking in public, but the problem is if they just kept locking people up over and over, they will just make the state broke. Otherwise I think this park is a good idea for the city, because it gives the institutionalized people somewhere to go without breaking the law.
Outside the park it's a little more lively with a bunch of youngsters running around rolling dice and slinging dope.
Old man can't play accordion

More issues with South Central

2012-11-04T08:48:00.001-08:00

Here is a few more pictures of bums on the street (Sunday all the businesses are closed, so the streets are quiet), but the biggest problem also is the track pickup schedule. They either need to increase the size of the trashcans, or they need to increase the amount of drivers and trucks picking up Tue trash. Like who owns the sidewalk?? I suppose because it belongs to the county, however I think it would be no small matter to keep the sidewalks pressure-washed, but 1/2 of these poeple don't speak English anyways lol. pic continued. Unfortunately I wanted to buy a pad-satchel, but everything is closed today. :-(

South Central Skid Row #2

2012-11-04T06:13:00.002-08:00

This is me testing my mobile blogging application, I decided to walk around when I woke up taking pictures of all the street people, a few of them are foreigners; one of them was a Vietnam Bet. I think they need a small computer center down here, since this place is totally offline except for 3g and Starbucks. it looks difficult to arrange photos on the o.line application, however these blogs can be edited later.

Los Angeles Skid Row Mini-Documentary Part 1

2012-11-03T11:55:00.002-07:00

Well! I just came down to South Central Los Angeles, because this is the only place that there is homeless shelters, there was none in Sacramento (Unfortunately the kindness of my parents only will go so far, but they have been good to me). I don't want to sound like Mein Kampf, but it is a slightly similar story (and I do have that Hitler-like glare, unfortunately he belongs in South Central with the rest of these Meth/Coke addicts)

I have been living outside of Civilization for quite some-time (About 6 months). My mother was kind enough to get me a quiet country trailer with W/P/S/AC where I could leave in peace and clean air. Unfortunately I had to come back to California to apply for an expungement. As you get closer to the street-people epicenter, the roll up doors with Hispanic and Asian business's fenced in line the up against the streets. I had to wait at the train station with my bags (I arrived at 2:30AM), where plenty of security was available, these bags weigh me down, and makes it difficult for me to defend in a street fight where I am encumbered slightly and drop my electronics bag, damaging my equipment.

Los Angeles is still very wealthy, as one block is filled in with nicely built public buildings with iconic architecture, but as I wander down to skid row, my heavy boots are unused to walking this kinda distance with blisters on my feet (thankfully I have some nice 11" Red-Wings, water-proof mudding boots (the same kind you use on oil rigs)).

In every alley, the stench of open urine and sewage fills the air, people sleeping in cardboard boxes, or plastic tents tied to shopping carts. I am not sure of the bed capacity down here, I was lucky enough to have a pre-arranged phone-call with my mother calling the shelter ahead of time.

I actually went to the wrong shelter before dawn (Union Gospel Mission), I had about 10% battery left on my trusty hand-held android, when I got a text message for the correct place (Emmanuel Baptist Rescue Mission). This little $500.00 computer has been a lifesaver ($40.00 a month with insurance in case I drop it, with synced google accounts (Iphone's can suck it)).

The first problem I can see is that the sidewalks need to be pressure washed, there is so much gunk on the sidewalk I sat down in I am kinda worried about bacteria at this point or staph infections, and it kinda hurts to stand up for that period of time. Some people are creative using lawnchair's and what-not to just crash on the street like straight up Snoop-Dawg.

What I don't seem to understand is why many people are unwilling to live in the shelter's. Many of these people choose to remain addicted to their drug addictions as street people, refusing to live in shelters (because of the warm weather); because they refuse to follow directions or stop their drug addictions.

There is many cripple's on SSLA skid-row, running around with false legs, and wheelchairs (especially the elderly). 85% of these people are African-Americans with drug addictions and criminal records (I want to take some stats survey's soon, to get a more realistic picture of what is going on.)

Nobody seemed very willing to try to attack me or mad-dog (it might be my clothing, or my face; when I did time a few years back I had to stand up or retreat from team's of 4-5 people at least 3-4 times, I never had backup; I've been lucky so far, I just don't try to push my luck). There definitely isn't any good looking women out there (most of the women are not physically attractive or elderly, which accounts for them being on the street; Put Beyonce out there with me and watch how fast she gets off of the street.)

One thing that is nice to see, unlike India or Bangladesh; is that there is no children on the streets because of foster care/ orphanages/ CPS There was a long line out-side for food (but most of the people get food-stamps and what-not anyways, which gives plenty of food. In NC, the welfare policies are different it's based on sex/race/age/health/marital-status/children unlike California.

I have seen maybe 10 white people on the street, most of them look like they have drug problems.
I am definitely going to have to stop smoking outside; I worry about when the rainy season comes the moisture can definitely give you consumption (Tuberculosis), and I'll need watch where I sit. Furthermore the health department needs to regulate these Charities, (I had a stale-donut earler, but it wasn't bad I love stale bread anyways). =)

I do not understand how these people survive in this petri-dish (coming from school in a bio-med lab), I am definitely going to have to get some anti-bacterial soap and maybe a nasal-face-mask. I might have caught a cold already from the door-handles (I am not sure haha). I think TB is a serious problem out here, which needs to be fixed by the LA county enforcing clean pressure-washed sidewalks, and putting people into a squatters lot.

One thing that gets me upset is about these people passing out alcohol to these old alcoholics, is that they drink 1/2 a 40 oz. and they start getting the shakes (Like seriously they need to start to mandatory control these things (I am not a cop but giving alcohol to people with the shakes is ridiculous).

I bought a pack of Kools when I got in from Union Central to calm my nerves a bit (It's been at least 10 year's since I've been down here).

Then some skinny black-dude rolled up on me asking for a lighter, so thinking he was going to light up a cigarette, he pulls out a crack pipe and starts smoking with my lighter. My lighter being contaminated, I just sighed, handed him the rest of my pack of smokes, and let him keep the lighter. I don't need cocaine-particulates in my blood stream, Menthol tobacco is already starting to make the right side of my body feel funny (that's why I have been limiting my intake and taking an aspirin a day)...=)

Ironic that at the same time, the black community is playing the Gospel music full blare at 7:30 in the morning, with this long food line of old ex-cons. The strange thing about homeless shelter's is, they kick everyone out during the day (I am not sure for what purpose), and they wouldn't let me check in my heavy bags. It's ok.

Many of the people talk to themselves, from their schizophrenia-split-brain issues, or the lack of inter-personal-relationships.

I had a good conversation with about five of the older black guy's out there, they undeniably support President Obama. Some of the guy's have been to prison, and they haven't yet obtained certificates of rehabilitation, so they can't get jobs or loans, and forced into welfare and poverty.

I started talking about options and asked them why they live in the inner city; I explained how North Carolina is actually a much better place for blacks (as there is black owned business's with black employees, black universities, and they are screaming out here about stopping segregation.) I told them they would have a lot better quality of life living on welfare in a country trailer, but they just try to say that white people will abuse them and treat them like Negro slaves on a plantation, and yet I suspect they stay in the inner city, because of the lack of need for vehicles and maintenance, also the availability of drugs keeps them here in the inner city to satisfy their addictions.

I just don't understand how homeless inner-city blacks are more concerned with satisfying their drug addictions and saying that white males are going to enslave them if they move out into rural areas. I was arguing with them about how many black farmers there are in NC, and how there is a lot more of an older African-American labor class in the south, whereas I have not seen this in my 27 years of living in the west, where the major California cities are filled with trash, human refuse, and yet they are threatening riots of a republican is elected.

I reminded them that 5 votes in California is worth 1 vote in a small mid-western state or on the east, and also suggested that some of them head up to Massachusetts to take advantage of the Anti-discrimination laws. Some of these guys have felonies that are 20 years old, and the state stops publishing criminal records after 7 years (I myself am scrambling to get my record reduced to go back to work with hearings scheduled in a few months.)

I am definitely arguing in favor of two options, either one; a real ghetto such as Amsterdam is established, as a legal drug zone for junkies to live in, that is separate from the shelters. I haven't seen the crips/bloods or Sureno's out in force yet, this really is just a bunch of OG's trying to survive; Or they declare martial law on the inner cities, set up tent cities with federal enforcement on the drug trade and bum/camps that are military police'd. I think the current status quo, relying on the church donations from the people to fund these homeless shelter's is not good enough.