http://feeds.feedburner.com/clinicaladvisorwebexclusives Latest articles from The Clinical Advisor Web Exclusives Web Exclusives Web Exclusives custserv@haymarketmedia.com no After primary care patients received invitations in the mail for colorectal cancer screening by fecal immunochemical testing or colonoscopy, results show that more patients invited to screen for colonoscopy switched to FIT. https://www.clinicaladvisor.com/colorectal-cancer-screening-outreach-strategy-in-primary-care/article/833466/ Wed, 13 Feb 2019 14:00:00 GMT After primary care patients received invitations in the mail for colorectal cancer screening by fecal immunochemical testing or colonoscopy, results show that more patients invited to screen for colonoscopy switched to FIT. https://www.clinicaladvisor.com/colorectal-cancer-screening-outreach-strategy-in-primary-care/article/833466/ The Vaccine Injury Compensation Program was developed to offer financial assistance for those harmed by a vaccine. https://www.clinicaladvisor.com/vaccine-injury-compensation-program-immunization/article/833785/ Wed, 13 Feb 2019 14:00:00 GMT The Vaccine Injury Compensation Program was developed to offer financial assistance for those harmed by a vaccine. https://www.clinicaladvisor.com/vaccine-injury-compensation-program-immunization/article/833785/ Endometrial scratching with the use of a pipelle biopsy may not increase live birth rates for women undergoing in vitro fertilization. https://www.clinicaladvisor.com/ivf-live-birth-rates-not-increased-with-endometrial-scratching/article/833465/ Wed, 13 Feb 2019 14:00:00 GMT Endometrial scratching with the use of a pipelle biopsy may not increase live birth rates for women undergoing in vitro fertilization. https://www.clinicaladvisor.com/ivf-live-birth-rates-not-increased-with-endometrial-scratching/article/833465/ Topline data from the Phase 3 STELLAR-4 trial showed that selonsertib, an investigational treatment for patients with compensated cirrhosis due to nonalcoholic steatohepatitis (NASH), was not associated with a significant improvement in fibrosis without worsening of NASH. https://www.clinicaladvisor.com/topline-data-announced-for-selonsertib-in-patients-with-compensated-cirrhosis-due-to-nash/article/833789/ Wed, 13 Feb 2019 14:00:00 GMT Topline data from the Phase 3 STELLAR-4 trial showed that selonsertib, an investigational treatment for patients with compensated cirrhosis due to nonalcoholic steatohepatitis (NASH), was not associated with a significant improvement in fibrosis without worsening of NASH. https://www.clinicaladvisor.com/topline-data-announced-for-selonsertib-in-patients-with-compensated-cirrhosis-due-to-nash/article/833789/ The FDA has announced a new plan to significantly modernize the regulation and oversight of dietary supplements. https://www.clinicaladvisor.com/dietary-supplement-industry-regulation-oversight-fda/article/833476/ Tue, 12 Feb 2019 14:00:00 GMT The FDA has announced a new plan to significantly modernize the regulation and oversight of dietary supplements. https://www.clinicaladvisor.com/dietary-supplement-industry-regulation-oversight-fda/article/833476/ Children's ability to develop may be hindered by excessive screen time. https://www.clinicaladvisor.com/increased-screen-inversely-related-to-child-development/article/833259/ Tue, 12 Feb 2019 14:00:00 GMT Children's ability to develop may be hindered by excessive screen time. https://www.clinicaladvisor.com/increased-screen-inversely-related-to-child-development/article/833259/ Measuring serum estradiol during the menopausal transition might help identify women at higher risk for fractures. https://www.clinicaladvisor.com/associations-of-fracture-risk-and-hormone-measurements-in-menopause-transition/article/833468/ Tue, 12 Feb 2019 14:00:00 GMT Measuring serum estradiol during the menopausal transition might help identify women at higher risk for fractures. https://www.clinicaladvisor.com/associations-of-fracture-risk-and-hormone-measurements-in-menopause-transition/article/833468/ Aspirin may be linked to an increased risk of major bleeding and decreased risk of cardiovascular events in individuals without cardiovascular disease. https://www.clinicaladvisor.com/aspirin-for-cv-primary-prevention-may-cause-major-bleeding/article/833247/ Tue, 12 Feb 2019 13:59:00 GMT Aspirin may be linked to an increased risk of major bleeding and decreased risk of cardiovascular events in individuals without cardiovascular disease. https://www.clinicaladvisor.com/aspirin-for-cv-primary-prevention-may-cause-major-bleeding/article/833247/ Women who were born at a low birth weight and who are overweight or obese as adults are at increased risk of developing preeclampsia, gestational hypertension, and gestational diabetes mellitus. https://www.clinicaladvisor.com/low-birth-weight-obesity-linked-to-pregnancy-complications/article/833151/ Mon, 11 Feb 2019 14:00:00 GMT Women who were born at a low birth weight and who are overweight or obese as adults are at increased risk of developing preeclampsia, gestational hypertension, and gestational diabetes mellitus. https://www.clinicaladvisor.com/low-birth-weight-obesity-linked-to-pregnancy-complications/article/833151/ Data do not support the use of an MRI-guided treat-to-target strategy for treating patients with rheumatoid arthritis. https://www.clinicaladvisor.com/mri-guided-treat-to-target-strategy-in-rheumatoid-arthritis/article/833144/ Mon, 11 Feb 2019 14:00:00 GMT Data do not support the use of an MRI-guided treat-to-target strategy for treating patients with rheumatoid arthritis. https://www.clinicaladvisor.com/mri-guided-treat-to-target-strategy-in-rheumatoid-arthritis/article/833144/ Researchers used data from the Medical Expenditure Panel Survey to examine whether visits to primary care providers resulted in high-value or low-value care, as well as the impact of those visits on patient access to and experience with health care. https://www.clinicaladvisor.com/primary-care-linked-to-more-high-value-care/article/833152/ Mon, 11 Feb 2019 14:00:00 GMT Researchers used data from the Medical Expenditure Panel Survey to examine whether visits to primary care providers resulted in high-value or low-value care, as well as the impact of those visits on patient access to and experience with health care. https://www.clinicaladvisor.com/primary-care-linked-to-more-high-value-care/article/833152/ Slump stretching may be beneficial to individuals with low back pain, based on very low to moderate quality evidence. https://www.clinicaladvisor.com/slump-stretching-may-be-beneficial-to-individuals-with-low-back-pain/article/833143/ Mon, 11 Feb 2019 14:00:00 GMT Slump stretching may be beneficial to individuals with low back pain, based on very low to moderate quality evidence. https://www.clinicaladvisor.com/slump-stretching-may-be-beneficial-to-individuals-with-low-back-pain/article/833143/ Investigators sought to determine the benefit of statin therapy, particularly as patients age. https://www.clinicaladvisor.com/statin-therapy-major-vascular-events-smaller-reductions-with-age/article/832846/ Fri, 08 Feb 2019 11:00:00 GMT Investigators sought to determine the benefit of statin therapy, particularly as patients age. https://www.clinicaladvisor.com/statin-therapy-major-vascular-events-smaller-reductions-with-age/article/832846/ Physician-mothers who care for seriously ill children, spouses, or parents have higher rates of burnout and mood disorders. https://www.clinicaladvisor.com/caregiver-physician-mother-burnout/article/832847/ Fri, 08 Feb 2019 10:00:00 GMT Physician-mothers who care for seriously ill children, spouses, or parents have higher rates of burnout and mood disorders. https://www.clinicaladvisor.com/caregiver-physician-mother-burnout/article/832847/ Each DocuSol Kids mini-enema (5mL) contains a delivered dose of docusate sodium 100mg in a polyethylene glycol base. https://www.clinicaladvisor.com/docusol-kids-mini-enemas-for-general-constipation-in-children/article/832688/ Thu, 07 Feb 2019 14:00:00 GMT Each DocuSol Kids mini-enema (5mL) contains a delivered dose of docusate sodium 100mg in a polyethylene glycol base. https://www.clinicaladvisor.com/docusol-kids-mini-enemas-for-general-constipation-in-children/article/832688/ Parents of racial or ethnic minority adolescents were more likely to inaccurately report HPV vaccination initiation. https://www.clinicaladvisor.com/hpv-vaccination-coverage-reporting-inaccuracies/article/832272/ Thu, 07 Feb 2019 14:00:00 GMT Parents of racial or ethnic minority adolescents were more likely to inaccurately report HPV vaccination initiation. https://www.clinicaladvisor.com/hpv-vaccination-coverage-reporting-inaccuracies/article/832272/ Data show that current smoking status was inversely associated with primary Sjogren syndrome. https://www.clinicaladvisor.com/effects-of-smoking-obesity-in-primary-sjogren-syndrome/article/832577/ Thu, 07 Feb 2019 14:00:00 GMT Data show that current smoking status was inversely associated with primary Sjogren syndrome. https://www.clinicaladvisor.com/effects-of-smoking-obesity-in-primary-sjogren-syndrome/article/832577/ HIV self-test kits combined with financial incentives may encourage men to attend the clinic for post-test HIV services. https://www.clinicaladvisor.com/offering-pregnant-women-at-hiv-clinics-self-tests-for-their-partners-is-successful/article/832268/ Wed, 06 Feb 2019 14:00:00 GMT HIV self-test kits combined with financial incentives may encourage men to attend the clinic for post-test HIV services. https://www.clinicaladvisor.com/offering-pregnant-women-at-hiv-clinics-self-tests-for-their-partners-is-successful/article/832268/ Introduction of the oral rotovirus vaccine in Australia was associated with a decline in the incidence of type 1 diabetes. https://www.clinicaladvisor.com/introduction-of-oral-rotavirus-vaccine-decreased-t1d-cases-in-children/article/832270/ Wed, 06 Feb 2019 14:00:00 GMT Introduction of the oral rotovirus vaccine in Australia was associated with a decline in the incidence of type 1 diabetes. https://www.clinicaladvisor.com/introduction-of-oral-rotavirus-vaccine-decreased-t1d-cases-in-children/article/832270/ Terrific Care/Medex Supply had purchased these test strips (which were distributed by Roche Diagnostics outside the country) from an unknown source, imported and sold them in the US. https://www.clinicaladvisor.com/inr-test-strip-recall-coaguchek-xs-pt-terrific-care-medex-supply/article/831953/ Tue, 05 Feb 2019 14:00:00 GMT Terrific Care/Medex Supply had purchased these test strips (which were distributed by Roche Diagnostics outside the country) from an unknown source, imported and sold them in the US. https://www.clinicaladvisor.com/inr-test-strip-recall-coaguchek-xs-pt-terrific-care-medex-supply/article/831953/ Researchers found that medication overuse is linked to migraines. https://www.clinicaladvisor.com/headache-frequency-medication-overuse-and-depression-linked-to-migraine/article/831761/ Tue, 05 Feb 2019 14:00:00 GMT Researchers found that medication overuse is linked to migraines. https://www.clinicaladvisor.com/headache-frequency-medication-overuse-and-depression-linked-to-migraine/article/831761/ Metagenomic sequencing identified genetically distinct, chronologically overlapping case clusters during a hospital-associated norovirus outbreak. https://www.clinicaladvisor.com/new-viral-sequencing-test-shows-geographical-grouping-of-nosocomial-outbreaks/article/831766/ Tue, 05 Feb 2019 14:00:00 GMT Metagenomic sequencing identified genetically distinct, chronologically overlapping case clusters during a hospital-associated norovirus outbreak. https://www.clinicaladvisor.com/new-viral-sequencing-test-shows-geographical-grouping-of-nosocomial-outbreaks/article/831766/ The American Heart Association launched in December 2018 a 30 minute-long online course titled "Opioid Education for Healthcare Providers." https://www.clinicaladvisor.com/american-heart-association-course-on-opioid-epidemic-treatment-of-opioid-overdose/article/831617/ Mon, 04 Feb 2019 14:00:00 GMT The American Heart Association launched in December 2018 a 30 minute-long online course titled "Opioid Education for Healthcare Providers." https://www.clinicaladvisor.com/american-heart-association-course-on-opioid-epidemic-treatment-of-opioid-overdose/article/831617/ Study showed an association between depression in fathers during the postnatal period and subsequent depression in girls at age 18 years. https://www.clinicaladvisor.com/postnatal-paternal-depression-associated-with-depression-in-girls/article/831618/ Mon, 04 Feb 2019 14:00:00 GMT Study showed an association between depression in fathers during the postnatal period and subsequent depression in girls at age 18 years. https://www.clinicaladvisor.com/postnatal-paternal-depression-associated-with-depression-in-girls/article/831618/ The duration of antibiotic regimens to treat lower respiratory tract infection can be reduced through the use of a procalcitonin-guided algorithm. https://www.clinicaladvisor.com/lower-respiratory-tract-infection-antibiotic-use-reduced-with-algorithm/article/831620/ Mon, 04 Feb 2019 12:00:00 GMT The duration of antibiotic regimens to treat lower respiratory tract infection can be reduced through the use of a procalcitonin-guided algorithm. https://www.clinicaladvisor.com/lower-respiratory-tract-infection-antibiotic-use-reduced-with-algorithm/article/831620/ Compared with wait times at VA health centers, wait times in the private sector remained static. https://www.clinicaladvisor.com/va-vs-private-sector-patient-wait-times/article/830884/ Fri, 01 Feb 2019 14:52:00 GMT Compared with wait times at VA health centers, wait times in the private sector remained static. https://www.clinicaladvisor.com/va-vs-private-sector-patient-wait-times/article/830884/ Maternal use of ondansetron during the first trimester of pregnancy was not found to be associated with cardiac or congenital malformation in offspring but may be linked to oral cleft development. https://www.clinicaladvisor.com/maternal-ondansetron-exposure-risk-of-cardiac-malformation-oral-cleft-in-offspring/article/829792/ Thu, 31 Jan 2019 14:00:00 GMT Maternal use of ondansetron during the first trimester of pregnancy was not found to be associated with cardiac or congenital malformation in offspring but may be linked to oral cleft development. https://www.clinicaladvisor.com/maternal-ondansetron-exposure-risk-of-cardiac-malformation-oral-cleft-in-offspring/article/829792/ Investigators evaluated whether treatment with one year of oral or transdermal administration of estrogen plus cyproterone and transdermal or intramuscular application of testosterone caused changes in serum lipids and blood pressure. https://www.clinicaladvisor.com/hormone-therapy-and-lipid-profiles-cvd-in-transgender-persons/article/830409/ Thu, 31 Jan 2019 14:00:00 GMT Investigators evaluated whether treatment with one year of oral or transdermal administration of estrogen plus cyproterone and transdermal or intramuscular application of testosterone caused changes in serum lipids and blood pressure. https://www.clinicaladvisor.com/hormone-therapy-and-lipid-profiles-cvd-in-transgender-persons/article/830409/ The expanded approval was based on safety and efficacy data from a confirmatory Phase 3 randomized, double-blind, placebo-controlled multicenter study evaluating Osphena in patients with moderate to severe vaginal dryness. https://www.clinicaladvisor.com/osphena-vaginal-dryness-indication-approved/article/830405/ Thu, 31 Jan 2019 14:00:00 GMT The expanded approval was based on safety and efficacy data from a confirmatory Phase 3 randomized, double-blind, placebo-controlled multicenter study evaluating Osphena in patients with moderate to severe vaginal dryness. https://www.clinicaladvisor.com/osphena-vaginal-dryness-indication-approved/article/830405/ Tosymra is an intranasal spray containing sumatriptan 10mg, a selective 5-HT1B/1D receptor agonist. https://www.clinicaladvisor.com/tosymra-dfn-02-approved-by-fda-for-acute-migraines/article/830311/ Thu, 31 Jan 2019 14:00:00 GMT Tosymra is an intranasal spray containing sumatriptan 10mg, a selective 5-HT1B/1D receptor agonist. https://www.clinicaladvisor.com/tosymra-dfn-02-approved-by-fda-for-acute-migraines/article/830311/ Data underscore the prospective impact of parental drinking and psychiatric symptoms on childhood mental health outcomes. https://www.clinicaladvisor.com/parental-drinking-mental-health-has-impact-on-child-mental-health/article/830408/ Thu, 31 Jan 2019 14:00:00 GMT Data underscore the prospective impact of parental drinking and psychiatric symptoms on childhood mental health outcomes. https://www.clinicaladvisor.com/parental-drinking-mental-health-has-impact-on-child-mental-health/article/830408/ Investigators observed a link between food insecurity — difficulty affording enough food to support regular, balanced meals — and increased probability of binge-eating disorder and obesity, according to study results. https://www.clinicaladvisor.com/food-insecurity-binge-eating-disorder-obesity/article/830086/ Wed, 30 Jan 2019 14:00:00 GMT Investigators observed a link between food insecurity — difficulty affording enough food to support regular, balanced meals — and increased probability of binge-eating disorder and obesity, according to study results. https://www.clinicaladvisor.com/food-insecurity-binge-eating-disorder-obesity/article/830086/ Researchers assessed the efficacy and safety of lasmiditan (100 and 200 mg) to treat migraine. https://www.clinicaladvisor.com/lasmiditan-200-mg-100-mg-superior-to-placebo-for-migraine-in-patients-with-cardiovascular-risks/article/830085/ Wed, 30 Jan 2019 14:00:00 GMT Researchers assessed the efficacy and safety of lasmiditan (100 and 200 mg) to treat migraine. https://www.clinicaladvisor.com/lasmiditan-200-mg-100-mg-superior-to-placebo-for-migraine-in-patients-with-cardiovascular-risks/article/830085/ Even the use of as few as 2 concomitant drugs can introduce the risk for drug interactions and subsequent adverse effects. https://www.clinicaladvisor.com/iatrogenic-polypharmacy-management/article/829075/ Wed, 30 Jan 2019 14:00:00 GMT Even the use of as few as 2 concomitant drugs can introduce the risk for drug interactions and subsequent adverse effects. https://www.clinicaladvisor.com/iatrogenic-polypharmacy-management/article/829075/ Plasma testosterone levels are positively associated with overall body adiposity in postmenopausal women. https://www.clinicaladvisor.com/androgen-hormones-affect-adiposity-differently-between-genders/article/830088/ Wed, 30 Jan 2019 14:00:00 GMT Plasma testosterone levels are positively associated with overall body adiposity in postmenopausal women. https://www.clinicaladvisor.com/androgen-hormones-affect-adiposity-differently-between-genders/article/830088/ The ACR is urging CMS to adopt safeguards to protect Medicare Advantage beneficiaries from step therapy. https://www.clinicaladvisor.com/acr-responds-to-cms-medicare-part-d-medicare-advantage-proposed-rule/article/829988/ Tue, 29 Jan 2019 14:00:00 GMT The ACR is urging CMS to adopt safeguards to protect Medicare Advantage beneficiaries from step therapy. https://www.clinicaladvisor.com/acr-responds-to-cms-medicare-part-d-medicare-advantage-proposed-rule/article/829988/ Peripheral nerve decompression surgery may be effective in reducing migraine headache frequency and intensity. https://www.clinicaladvisor.com/peripheral-nerve-decompression-surgery-effective-in-reducing-migraine-frequency-intensity/article/829997/ Tue, 29 Jan 2019 14:00:00 GMT Peripheral nerve decompression surgery may be effective in reducing migraine headache frequency and intensity. https://www.clinicaladvisor.com/peripheral-nerve-decompression-surgery-effective-in-reducing-migraine-frequency-intensity/article/829997/ Due to brain excitability and hypoxia from coughing, patients with cystic fibrosis have a propensity for cortical spreading depression and hemiplegic migraine. https://www.clinicaladvisor.com/cystic-fibrosis-may-be-a-risk-factor-for-hemiplegic-migraine-and-stroke/article/829685/ Mon, 28 Jan 2019 14:00:00 GMT Due to brain excitability and hypoxia from coughing, patients with cystic fibrosis have a propensity for cortical spreading depression and hemiplegic migraine. https://www.clinicaladvisor.com/cystic-fibrosis-may-be-a-risk-factor-for-hemiplegic-migraine-and-stroke/article/829685/ Maternal glycemia during pregnancy may influence childhood glucose and insulin resistance regardless of BMI and family history of diabetes. https://www.clinicaladvisor.com/maternal-glucose-levels-during-pregnancy-may-affect-childhood-glucose-insulin-resistance/article/829680/ Mon, 28 Jan 2019 14:00:00 GMT Maternal glycemia during pregnancy may influence childhood glucose and insulin resistance regardless of BMI and family history of diabetes. https://www.clinicaladvisor.com/maternal-glucose-levels-during-pregnancy-may-affect-childhood-glucose-insulin-resistance/article/829680/ Postmenopausal women with persistent night sweats and/or hot flashes are more likely to be diagnosed with breast cancer compared with women without these vasomotor symptoms. https://www.clinicaladvisor.com/hot-flashes-night-sweats-linked-to-postmenopausal-breast-cancer/article/829687/ Mon, 28 Jan 2019 14:00:00 GMT Postmenopausal women with persistent night sweats and/or hot flashes are more likely to be diagnosed with breast cancer compared with women without these vasomotor symptoms. https://www.clinicaladvisor.com/hot-flashes-night-sweats-linked-to-postmenopausal-breast-cancer/article/829687/ A new clinical practice guidelines summary for clinicians regarding idiopathic pulmonary fibrosis has been released, which describes clinical manifestations and diagnostic interventions for the disease. https://www.clinicaladvisor.com/idiopathic-pulmonary-fibrosis-2018-diagnostic-guidelines/article/829686/ Mon, 28 Jan 2019 14:00:00 GMT A new clinical practice guidelines summary for clinicians regarding idiopathic pulmonary fibrosis has been released, which describes clinical manifestations and diagnostic interventions for the disease. https://www.clinicaladvisor.com/idiopathic-pulmonary-fibrosis-2018-diagnostic-guidelines/article/829686/ Researchers examined the safety, tolerability, and feasibility of young plasma infusion in patients with mild to moderate Alzheimer disease dementia in an Alzheimer's symptom amelioration study. https://www.clinicaladvisor.com/young-fresh-frozen-plasma-infusion-safe-feasible-treatment-alzheimer-disease/article/829684/ Mon, 28 Jan 2019 14:00:00 GMT Researchers examined the safety, tolerability, and feasibility of young plasma infusion in patients with mild to moderate Alzheimer disease dementia in an Alzheimer's symptom amelioration study. https://www.clinicaladvisor.com/young-fresh-frozen-plasma-infusion-safe-feasible-treatment-alzheimer-disease/article/829684/ Physical activity was found to be associated with a reduced risk for hepatocellular carcinoma. https://www.clinicaladvisor.com/physical-activity-and-risk-of-hcc/article/828872/ Fri, 25 Jan 2019 14:00:00 GMT Physical activity was found to be associated with a reduced risk for hepatocellular carcinoma. https://www.clinicaladvisor.com/physical-activity-and-risk-of-hcc/article/828872/ Investigators examine characteristics associated with disordered eating behaviors in teenagers with type 1 diabetes. https://www.clinicaladvisor.com/characteristics-of-disordered-eating-behaviors-in-teenagers-with-t1d/article/829375/ Fri, 25 Jan 2019 14:00:00 GMT Investigators examine characteristics associated with disordered eating behaviors in teenagers with type 1 diabetes. https://www.clinicaladvisor.com/characteristics-of-disordered-eating-behaviors-in-teenagers-with-t1d/article/829375/ Investigators confirmed an association between headache disorders and increased risk for dementia in this pooled meta-analysis; however, the number of studies was small and the population characteristics and study designs were quite heterogenous. https://www.clinicaladvisor.com/migraine-headache-history-dementia-risk-meta-analysis/article/829374/ Fri, 25 Jan 2019 13:30:00 GMT Investigators confirmed an association between headache disorders and increased risk for dementia in this pooled meta-analysis; however, the number of studies was small and the population characteristics and study designs were quite heterogenous. https://www.clinicaladvisor.com/migraine-headache-history-dementia-risk-meta-analysis/article/829374/ As the government shutdown drags in to its second month, physicians who treat opioid use disorders are being backed against a wall. https://www.clinicaladvisor.com/opioid-crisis-buprenorphine-waivers-dea-access/article/829070/ Thu, 24 Jan 2019 14:00:00 GMT As the government shutdown drags in to its second month, physicians who treat opioid use disorders are being backed against a wall. https://www.clinicaladvisor.com/opioid-crisis-buprenorphine-waivers-dea-access/article/829070/ Buprenorphine-naloxone may be more cost-effective than extended-release naltrexone as first-line treatment for opioid use disorder. https://www.clinicaladvisor.com/buprenorphine-naloxone-more-cost-effective-than-er-naltrexone-for-opioid-use-disorder/article/829074/ Thu, 24 Jan 2019 14:00:00 GMT Buprenorphine-naloxone may be more cost-effective than extended-release naltrexone as first-line treatment for opioid use disorder. https://www.clinicaladvisor.com/buprenorphine-naloxone-more-cost-effective-than-er-naltrexone-for-opioid-use-disorder/article/829074/ Is the risk of depression or self-harm greater in women who have experienced complications following transvaginal mesh midurethral sling placement? https://www.clinicaladvisor.com/transvaginal-mesh-midurethral-sling-complications-linked-to-depression-self-harm/article/828870/ Thu, 24 Jan 2019 14:00:00 GMT Is the risk of depression or self-harm greater in women who have experienced complications following transvaginal mesh midurethral sling placement? https://www.clinicaladvisor.com/transvaginal-mesh-midurethral-sling-complications-linked-to-depression-self-harm/article/828870/ Opioids may only provide limited benefits for the management of chronic noncancer pain and may be associated with a greater risk for vomiting. https://www.clinicaladvisor.com/opioids-may-lead-to-small-improvements-in-pain-and-physical-functioning-in-chronic-pain/article/828775/ Wed, 23 Jan 2019 14:00:00 GMT Opioids may only provide limited benefits for the management of chronic noncancer pain and may be associated with a greater risk for vomiting. https://www.clinicaladvisor.com/opioids-may-lead-to-small-improvements-in-pain-and-physical-functioning-in-chronic-pain/article/828775/ Postmenopausal women who completed a midwife-based counseling program saw improvements in sexual function compared with postmenopausal women who did not complete the counseling program. https://www.clinicaladvisor.com/midwife-based-education-program-improves-sexual-function-postmenopausal-women/article/827647/ Wed, 23 Jan 2019 14:00:00 GMT Postmenopausal women who completed a midwife-based counseling program saw improvements in sexual function compared with postmenopausal women who did not complete the counseling program. https://www.clinicaladvisor.com/midwife-based-education-program-improves-sexual-function-postmenopausal-women/article/827647/ Per study data published in the Journal of Clinical Psychiatry, investigators hypothesized that the correlation between higher Frailty Index scores and increased caregiver burden was partially mediated by increased behavioral and psychological symptoms of dementia. https://www.clinicaladvisor.com/physical-frailty-associated-with-dementia-symptoms-caregiver-burden-in-alzheimer-disease/article/828779/ Wed, 23 Jan 2019 14:00:00 GMT Per study data published in the Journal of Clinical Psychiatry, investigators hypothesized that the correlation between higher Frailty Index scores and increased caregiver burden was partially mediated by increased behavioral and psychological symptoms of dementia. https://www.clinicaladvisor.com/physical-frailty-associated-with-dementia-symptoms-caregiver-burden-in-alzheimer-disease/article/828779/ A 7-day antibiotic course has demonstrated noninferiority compared with a 14-day course in treating uncomplicated gram-negative bacteremia. https://www.clinicaladvisor.com/in-patients-with-uncomplicated-gram-neg-infections-7-days-abx-noninferior-to-14/article/828772/ Wed, 23 Jan 2019 14:00:00 GMT A 7-day antibiotic course has demonstrated noninferiority compared with a 14-day course in treating uncomplicated gram-negative bacteremia. https://www.clinicaladvisor.com/in-patients-with-uncomplicated-gram-neg-infections-7-days-abx-noninferior-to-14/article/828772/ Nonadherence to protocol screenings in a screening trial for multiple cancers may be linked to higher overall mortality, excluding mortality due to cancers studied in the trial. https://www.clinicaladvisor.com/nonadherence-to-cancer-screening-tests-linked-to-increased-overall-mortality/article/827959/ Tue, 22 Jan 2019 14:00:00 GMT Nonadherence to protocol screenings in a screening trial for multiple cancers may be linked to higher overall mortality, excluding mortality due to cancers studied in the trial. https://www.clinicaladvisor.com/nonadherence-to-cancer-screening-tests-linked-to-increased-overall-mortality/article/827959/ A greater number of early adverse life events as well as more severe traumatic experiences were found to be associated with an increased risk for developing irritable bowel syndrome. https://www.clinicaladvisor.com/adverse-life-advents-trauma-linked-to-ibs/article/827646/ Tue, 22 Jan 2019 14:00:00 GMT A greater number of early adverse life events as well as more severe traumatic experiences were found to be associated with an increased risk for developing irritable bowel syndrome. https://www.clinicaladvisor.com/adverse-life-advents-trauma-linked-to-ibs/article/827646/ Hormone therapy in postmenopausal women may be protective against knee OA. https://www.clinicaladvisor.com/hormone-replacement-therapy-may-decrease-prevalence-of-symptomatic-knee-arthritis/article/828159/ Tue, 22 Jan 2019 14:00:00 GMT Hormone therapy in postmenopausal women may be protective against knee OA. https://www.clinicaladvisor.com/hormone-replacement-therapy-may-decrease-prevalence-of-symptomatic-knee-arthritis/article/828159/ Study data found that a single 60-minute interview session may be sufficient for capturing obsessive-compulsive symptoms in youth. https://www.clinicaladvisor.com/interview-only-version-of-dy-bocs-effective-for-ocd-monitoring-in-youth/article/828160/ Tue, 22 Jan 2019 14:00:00 GMT Study data found that a single 60-minute interview session may be sufficient for capturing obsessive-compulsive symptoms in youth. https://www.clinicaladvisor.com/interview-only-version-of-dy-bocs-effective-for-ocd-monitoring-in-youth/article/828160/ The most cost-effective means of decreasing transmission of Zika virus is administration of the vaccine to young adults and women of childbearing age. https://www.clinicaladvisor.com/population-targeted-vaccination-for-zika-is-holds-highest-economic-value/article/828263/ Tue, 22 Jan 2019 14:00:00 GMT The most cost-effective means of decreasing transmission of Zika virus is administration of the vaccine to young adults and women of childbearing age. https://www.clinicaladvisor.com/population-targeted-vaccination-for-zika-is-holds-highest-economic-value/article/828263/ Talking to sick patients about their future health prospects is a challenge. https://www.clinicaladvisor.com/discussing-patient-prognosis/article/827963/ Mon, 21 Jan 2019 14:00:00 GMT Talking to sick patients about their future health prospects is a challenge. https://www.clinicaladvisor.com/discussing-patient-prognosis/article/827963/ Initiation and continuation trends in menopausal hormone therapy may have been influenced by the premature cessation of the 2002 Women's Health Initiative trial, which was halted due to safety concerns. https://www.clinicaladvisor.com/menopausal-hormone-therapy-trends-before-and-after-womens-health-initiative/article/827961/ Mon, 21 Jan 2019 14:00:00 GMT Initiation and continuation trends in menopausal hormone therapy may have been influenced by the premature cessation of the 2002 Women's Health Initiative trial, which was halted due to safety concerns. https://www.clinicaladvisor.com/menopausal-hormone-therapy-trends-before-and-after-womens-health-initiative/article/827961/ Despite the reduction in the ability to exercise free will associated with substance use disorders and the severity of these disorders, pregnancy appears to have protective effects. https://www.clinicaladvisor.com/pregnancy-reduces-risk-for-alcohol-use-disorder-among-women-and-their-partners/article/828146/ Mon, 21 Jan 2019 14:00:00 GMT Despite the reduction in the ability to exercise free will associated with substance use disorders and the severity of these disorders, pregnancy appears to have protective effects. https://www.clinicaladvisor.com/pregnancy-reduces-risk-for-alcohol-use-disorder-among-women-and-their-partners/article/828146/ Preconception hyperandrogenism and impaired glucose tolerance are predictive of multiple obstetric and perinatal complications in women with PCOS. https://www.clinicaladvisor.com/polycystic-ovary-syndrome-characteristics-before-conception-predict-neonatal-outcomes/article/828143/ Mon, 21 Jan 2019 14:00:00 GMT Preconception hyperandrogenism and impaired glucose tolerance are predictive of multiple obstetric and perinatal complications in women with PCOS. https://www.clinicaladvisor.com/polycystic-ovary-syndrome-characteristics-before-conception-predict-neonatal-outcomes/article/828143/ WHO named vaccine hesitancy a top 10 threat to global health in 2019. Hysteresis may describe persistent skepticism. https://www.clinicaladvisor.com/who-names-anti-vaccine-top-health-threat-hysteresis/article/828464/ Fri, 18 Jan 2019 20:00:00 GMT WHO named vaccine hesitancy a top 10 threat to global health in 2019. Hysteresis may describe persistent skepticism. https://www.clinicaladvisor.com/who-names-anti-vaccine-top-health-threat-hysteresis/article/828464/ The investigational drug is currently in Phase 1 development, with completion expected in the second quarter of 2019. https://www.clinicaladvisor.com/clostridium-difficile-infection-investigational-treatment-acx-362e-fast-track-designation/article/827950/ Fri, 18 Jan 2019 14:00:00 GMT The investigational drug is currently in Phase 1 development, with completion expected in the second quarter of 2019. https://www.clinicaladvisor.com/clostridium-difficile-infection-investigational-treatment-acx-362e-fast-track-designation/article/827950/ The number of enteric infection symptom reports was found to decrease with age, although older adults tend to have more severe illness and require hospitalization. https://www.clinicaladvisor.com/older-adults-report-enteric-infection-symptoms-less-than-younger-adults-children/article/827945/ Fri, 18 Jan 2019 14:00:00 GMT The number of enteric infection symptom reports was found to decrease with age, although older adults tend to have more severe illness and require hospitalization. https://www.clinicaladvisor.com/older-adults-report-enteric-infection-symptoms-less-than-younger-adults-children/article/827945/ For patients with both physical and mental health-related long-term conditions, missing healthcare appointments is associated with an increased risk of multimorbidity. https://www.clinicaladvisor.com/missed-general-practice-appointments-linked-to-mortality/article/827634/ Fri, 18 Jan 2019 14:00:00 GMT For patients with both physical and mental health-related long-term conditions, missing healthcare appointments is associated with an increased risk of multimorbidity. https://www.clinicaladvisor.com/missed-general-practice-appointments-linked-to-mortality/article/827634/ Between 2016 and 2017, the mean paid childbearing leave for faculty physicians at 12 top United States medical schools was just 8.6 weeks. https://www.clinicaladvisor.com/inadequate-parental-leave-policies/article/827954/ Fri, 18 Jan 2019 14:00:00 GMT Between 2016 and 2017, the mean paid childbearing leave for faculty physicians at 12 top United States medical schools was just 8.6 weeks. https://www.clinicaladvisor.com/inadequate-parental-leave-policies/article/827954/ Despite research suggesting that there may be increased cardiovascular risk from off-label prescription testosterone use, usage in men with coronary artery disease remains higher than in men without coronary artery disease. https://www.clinicaladvisor.com/testosterone-prescriptions-high-for-men-with-cad-despite-label-warnings/article/827953/ Fri, 18 Jan 2019 14:00:00 GMT Despite research suggesting that there may be increased cardiovascular risk from off-label prescription testosterone use, usage in men with coronary artery disease remains higher than in men without coronary artery disease. https://www.clinicaladvisor.com/testosterone-prescriptions-high-for-men-with-cad-despite-label-warnings/article/827953/ The Company has already completed a Phase 1 trial of this synthetic glucagon-like peptide (GLP-2) analog. https://www.clinicaladvisor.com/short-bowel-syndrome-treatment-apraglutide-granted-orphan-designation/article/827846/ Thu, 17 Jan 2019 17:05:00 GMT The Company has already completed a Phase 1 trial of this synthetic glucagon-like peptide (GLP-2) analog. https://www.clinicaladvisor.com/short-bowel-syndrome-treatment-apraglutide-granted-orphan-designation/article/827846/ Chronic infection with Giardia was associated with prolonged alterations in duodenal mucosa lymphocytes. https://www.clinicaladvisor.com/chronic-giardia-may-cause-prolonged-alterations-in-duodenal-mucosa-lymphocytes/article/827642/ Thu, 17 Jan 2019 14:00:00 GMT Chronic infection with Giardia was associated with prolonged alterations in duodenal mucosa lymphocytes. https://www.clinicaladvisor.com/chronic-giardia-may-cause-prolonged-alterations-in-duodenal-mucosa-lymphocytes/article/827642/ A task force of the International Association for the Study of Pain proposes a classification of chronic pain as either chronic primary or chronic secondary pain, when chronic pain represents the major complaint and when chronic pain is secondary to a chronic disorder, respectively. https://www.clinicaladvisor.com/chronic-pain-as-symptom-or-disease-primary-and-secondary-chronic-pain-iasp-icd-11/article/827636/ Thu, 17 Jan 2019 14:00:00 GMT A task force of the International Association for the Study of Pain proposes a classification of chronic pain as either chronic primary or chronic secondary pain, when chronic pain represents the major complaint and when chronic pain is secondary to a chronic disorder, respectively. https://www.clinicaladvisor.com/chronic-pain-as-symptom-or-disease-primary-and-secondary-chronic-pain-iasp-icd-11/article/827636/ The prevalence of anogenital warts has decreased, with significant declines observed in specific populations. https://www.clinicaladvisor.com/cases-of-anogenital-warts-decreasing-likely-as-a-result-of-increased-hpv-vaccination-rates/article/827639/ Thu, 17 Jan 2019 14:00:00 GMT The prevalence of anogenital warts has decreased, with significant declines observed in specific populations. https://www.clinicaladvisor.com/cases-of-anogenital-warts-decreasing-likely-as-a-result-of-increased-hpv-vaccination-rates/article/827639/ Data on adherence to the 2013 ACA/AHA cholesterol guidelines suggest significant underuse of appropriate-intensity statin therapy; however, data for statin use in primary prevention have been limited. https://www.clinicaladvisor.com/statin-therapy-frequently-not-initiated-before-first-acute-coronary-syndrome-event/article/827548/ Thu, 17 Jan 2019 14:00:00 GMT Data on adherence to the 2013 ACA/AHA cholesterol guidelines suggest significant underuse of appropriate-intensity statin therapy; however, data for statin use in primary prevention have been limited. https://www.clinicaladvisor.com/statin-therapy-frequently-not-initiated-before-first-acute-coronary-syndrome-event/article/827548/ The combined use of mometasone furoate and formoterol in adults and adolescents with persistent asthma may not increase asthma-related adverse events and may reduce the risk of worsening asthma outcomes. https://www.clinicaladvisor.com/combined-mometasone-furoate-formoterol-may-reduce-asthma-exacerbation-risk/article/827539/ Wed, 16 Jan 2019 14:00:00 GMT The combined use of mometasone furoate and formoterol in adults and adolescents with persistent asthma may not increase asthma-related adverse events and may reduce the risk of worsening asthma outcomes. https://www.clinicaladvisor.com/combined-mometasone-furoate-formoterol-may-reduce-asthma-exacerbation-risk/article/827539/ Eliminating routine oral opioid prescription following cesarean delivery may reduce opioid consumption without jeopardizing pain control or patient satisfaction. https://www.clinicaladvisor.com/pain-management-following-reduced-routine-opioid-use-after-cesarean-delivery/article/827546/ Wed, 16 Jan 2019 14:00:00 GMT Eliminating routine oral opioid prescription following cesarean delivery may reduce opioid consumption without jeopardizing pain control or patient satisfaction. https://www.clinicaladvisor.com/pain-management-following-reduced-routine-opioid-use-after-cesarean-delivery/article/827546/ Tuberculosis screening results may differ depending on blood draw methods. https://www.clinicaladvisor.com/tuberculosis-assay-may-be-affected-by-blood-draw-method/article/827335/ Wed, 16 Jan 2019 14:00:00 GMT Tuberculosis screening results may differ depending on blood draw methods. https://www.clinicaladvisor.com/tuberculosis-assay-may-be-affected-by-blood-draw-method/article/827335/ Fatigue and depressive symptoms had a negative effect on work stability in patients with ankylosing spondylitis. https://www.clinicaladvisor.com/fatigue-depression-linked-to-work-instability-in-ankylosing-spondylitis/article/827532/ Wed, 16 Jan 2019 14:00:00 GMT Fatigue and depressive symptoms had a negative effect on work stability in patients with ankylosing spondylitis. https://www.clinicaladvisor.com/fatigue-depression-linked-to-work-instability-in-ankylosing-spondylitis/article/827532/ A review of the 2016 American Heart Association and American College of Cardiology guidelines for management and diagnosis of peripheral arterial disease. https://www.clinicaladvisor.com/pad-diagnosis-management-updates/article/827331/ Tue, 15 Jan 2019 16:13:19 GMT A review of the 2016 American Heart Association and American College of Cardiology guidelines for management and diagnosis of peripheral arterial disease. https://www.clinicaladvisor.com/pad-diagnosis-management-updates/article/827331/ Researchers evaluated the efficacy and safety of anakinra for the treatment of acute gout flares. https://www.clinicaladvisor.com/acute-gout-flares-effectively-treated-with-anakinra/article/827008/ Tue, 15 Jan 2019 14:00:00 GMT Researchers evaluated the efficacy and safety of anakinra for the treatment of acute gout flares. https://www.clinicaladvisor.com/acute-gout-flares-effectively-treated-with-anakinra/article/827008/ Releasing report cards on Fridays may increase the rate of child physical abuse on the following Saturday. https://www.clinicaladvisor.com/child-abuse-report-card-release-link/article/827195/ Tue, 15 Jan 2019 14:00:00 GMT Releasing report cards on Fridays may increase the rate of child physical abuse on the following Saturday. https://www.clinicaladvisor.com/child-abuse-report-card-release-link/article/827195/ Pulsed ultrasound treatment may represent an effective option for the treatment of stable rib fractures. https://www.clinicaladvisor.com/pulsed-ultrasound-found-to-reduce-pain-accelerate-callus-healing-related-to-rib-fracture/article/827198/ Tue, 15 Jan 2019 14:00:00 GMT Pulsed ultrasound treatment may represent an effective option for the treatment of stable rib fractures. https://www.clinicaladvisor.com/pulsed-ultrasound-found-to-reduce-pain-accelerate-callus-healing-related-to-rib-fracture/article/827198/ Short-term pasteurization of breast milk may reduce the incidence of postnatally acquired cytomegalovirus infection through breast milk. https://www.clinicaladvisor.com/pasteurizing-breast-milk-for-5-seconds-may-prevent-transmission-of-cytomegalovirus/article/826585/ Mon, 14 Jan 2019 14:00:00 GMT Short-term pasteurization of breast milk may reduce the incidence of postnatally acquired cytomegalovirus infection through breast milk. https://www.clinicaladvisor.com/pasteurizing-breast-milk-for-5-seconds-may-prevent-transmission-of-cytomegalovirus/article/826585/ Children with croup who were given glucocorticoids had reduced symptoms at 2 through 24 hours. https://www.clinicaladvisor.com/glucocorticoids-reduced-croup-symptoms-and-hospital-return-visits/article/826888/ Mon, 14 Jan 2019 14:00:00 GMT Children with croup who were given glucocorticoids had reduced symptoms at 2 through 24 hours. https://www.clinicaladvisor.com/glucocorticoids-reduced-croup-symptoms-and-hospital-return-visits/article/826888/ The Psoriatic Arthritis Impact of Disease questionnaire was endorsed as a core outcome measure for psoriatic arthritis-specific health-related quality of life. https://www.clinicaladvisor.com/patient-reported-outcome-measure-endorsed-as-core-outcome-measure-for-psoriatic-arthritis-qol/article/826890/ Mon, 14 Jan 2019 14:00:00 GMT The Psoriatic Arthritis Impact of Disease questionnaire was endorsed as a core outcome measure for psoriatic arthritis-specific health-related quality of life. https://www.clinicaladvisor.com/patient-reported-outcome-measure-endorsed-as-core-outcome-measure-for-psoriatic-arthritis-qol/article/826890/ The need for effective osteoporosis screening tools and treatment strategies is high, as the current methods have a low sensitivity for determining postmenopausal women at risk for a major osteoporotic fracture. https://www.clinicaladvisor.com/united-states-vs-canadian-methods-for-osteoporosis-screening-and-treatment/article/826887/ Mon, 14 Jan 2019 13:00:00 GMT The need for effective osteoporosis screening tools and treatment strategies is high, as the current methods have a low sensitivity for determining postmenopausal women at risk for a major osteoporotic fracture. https://www.clinicaladvisor.com/united-states-vs-canadian-methods-for-osteoporosis-screening-and-treatment/article/826887/ Patients with Crohn disease were enrolled in a comparative cohort study that analyzed the outcomes of reference product infliximab vs biosimilar treatment. https://www.clinicaladvisor.com/biosimilar-vs-reference-infliximab-for-crohn-disease/article/826680/ Fri, 11 Jan 2019 14:32:26 GMT Patients with Crohn disease were enrolled in a comparative cohort study that analyzed the outcomes of reference product infliximab vs biosimilar treatment. https://www.clinicaladvisor.com/biosimilar-vs-reference-infliximab-for-crohn-disease/article/826680/ Weighted and combined multi-gene pharmacogenomic testing significantly increased clinical response and remission rates for patients with major depressive disorder. https://www.clinicaladvisor.com/effects-of-pharmacogenomics-on-major-depressive-disorder-clinical-outcomes/article/826564/ Fri, 11 Jan 2019 14:00:00 GMT Weighted and combined multi-gene pharmacogenomic testing significantly increased clinical response and remission rates for patients with major depressive disorder. https://www.clinicaladvisor.com/effects-of-pharmacogenomics-on-major-depressive-disorder-clinical-outcomes/article/826564/ Minimum inhibitory concentration levels of resistance to either clarithromycin or metronidazole may play a role in Helicobacter pylori therapy outcome. https://www.clinicaladvisor.com/low-inimum-inhibitory-concentration-linked-with-improved-cure-rate-for-resistant-h-pylori/article/826674/ Fri, 11 Jan 2019 13:30:00 GMT Minimum inhibitory concentration levels of resistance to either clarithromycin or metronidazole may play a role in Helicobacter pylori therapy outcome. https://www.clinicaladvisor.com/low-inimum-inhibitory-concentration-linked-with-improved-cure-rate-for-resistant-h-pylori/article/826674/ Regular and prolonged walking was found to be associated with a reduced the risk for low back pain in Koreans age >50. https://www.clinicaladvisor.com/regular-frequent-prolonged-walking-associated-with-reduced-risk-for-low-back-pain-in-older-koreans/article/826086/ Thu, 10 Jan 2019 14:00:00 GMT Regular and prolonged walking was found to be associated with a reduced the risk for low back pain in Koreans age >50. https://www.clinicaladvisor.com/regular-frequent-prolonged-walking-associated-with-reduced-risk-for-low-back-pain-in-older-koreans/article/826086/ Adults hospitalized for pneumonia who received an influenza vaccination during their stay were less likely to seroconvert if they had diabetes, bacterial detection, baseline seropositive titers for influenza B, or influenza vaccination in the previous season. https://www.clinicaladvisor.com/influenza-seroconversion-risk-factors-in-adults-hospitalized-with-pneumonia/article/826084/ Thu, 10 Jan 2019 14:00:00 GMT Adults hospitalized for pneumonia who received an influenza vaccination during their stay were less likely to seroconvert if they had diabetes, bacterial detection, baseline seropositive titers for influenza B, or influenza vaccination in the previous season. https://www.clinicaladvisor.com/influenza-seroconversion-risk-factors-in-adults-hospitalized-with-pneumonia/article/826084/ The American Headache Society has issued updated guidelines on the use of novel preventive and acute treatments for migraine in adults. https://www.clinicaladvisor.com/ahs-position-statement-preventive-acute-migraine-therapy/article/826282/ Wed, 09 Jan 2019 20:12:54 GMT The American Headache Society has issued updated guidelines on the use of novel preventive and acute treatments for migraine in adults. https://www.clinicaladvisor.com/ahs-position-statement-preventive-acute-migraine-therapy/article/826282/ HeartGuide is designed as a wrist watch that uses the oscillometric cuff method, the standard for medical-grade personal blood pressure measurement. https://www.clinicaladvisor.com/heartguide-smartwatch-blood-pressure-monitoring-omron-healthcare/article/826567/ Wed, 09 Jan 2019 16:00:00 GMT HeartGuide is designed as a wrist watch that uses the oscillometric cuff method, the standard for medical-grade personal blood pressure measurement. https://www.clinicaladvisor.com/heartguide-smartwatch-blood-pressure-monitoring-omron-healthcare/article/826567/ An informational intervention — including weight management and regular self-weighing — can help curb weight gain during the holiday season. https://www.clinicaladvisor.com/reducing-holiday-weight-gain-information-intervention/article/825970/ Wed, 09 Jan 2019 14:00:00 GMT An informational intervention — including weight management and regular self-weighing — can help curb weight gain during the holiday season. https://www.clinicaladvisor.com/reducing-holiday-weight-gain-information-intervention/article/825970/ Researchers assessed risk factors for cytomegalovirus antigenemia in pediatric patients. https://www.clinicaladvisor.com/identifying-risk-factors-cytomegalovirus-antigenemia-pediatric-patients/article/825649/ Tue, 08 Jan 2019 14:30:00 GMT Researchers assessed risk factors for cytomegalovirus antigenemia in pediatric patients. https://www.clinicaladvisor.com/identifying-risk-factors-cytomegalovirus-antigenemia-pediatric-patients/article/825649/ While evidence-based guidelines exist for the determination of brain death in infants, children, and adults, Nevada is currently the only state to adopt laws that require adherence to these guidelines. https://www.clinicaladvisor.com/american-academy-neurology-requests-brain-death-legislation-uniformed-medical-practice/article/825645/ Tue, 08 Jan 2019 14:00:00 GMT While evidence-based guidelines exist for the determination of brain death in infants, children, and adults, Nevada is currently the only state to adopt laws that require adherence to these guidelines. https://www.clinicaladvisor.com/american-academy-neurology-requests-brain-death-legislation-uniformed-medical-practice/article/825645/ Although treatment as usual for psychosis is guideline-congruent and well implemented, there appears to be no added value for adjunct cognitive behavioral therapy for social activation, according to the results of a study from the Netherlands. https://www.clinicaladvisor.com/cbt-for-social-activation-in-schizophrenia-not-cost-effective/article/825651/ Tue, 08 Jan 2019 14:00:00 GMT Although treatment as usual for psychosis is guideline-congruent and well implemented, there appears to be no added value for adjunct cognitive behavioral therapy for social activation, according to the results of a study from the Netherlands. https://www.clinicaladvisor.com/cbt-for-social-activation-in-schizophrenia-not-cost-effective/article/825651/ An expert panel assessed 41 diets to come up with their final results, examining the evidence behind each diet's claims, the short-term and long-term weight loss associated with the diet, how easy the diet is to follow, how well each diet conforms to current nutrition standards, and its effect on diabetes and cardiovascular disease prevention. https://www.clinicaladvisor.com/diet-rankings-2019-mediterranean-diet-dash-mind-weight-watchers/article/825327/ Mon, 07 Jan 2019 14:00:00 GMT An expert panel assessed 41 diets to come up with their final results, examining the evidence behind each diet's claims, the short-term and long-term weight loss associated with the diet, how easy the diet is to follow, how well each diet conforms to current nutrition standards, and its effect on diabetes and cardiovascular disease prevention. https://www.clinicaladvisor.com/diet-rankings-2019-mediterranean-diet-dash-mind-weight-watchers/article/825327/ Racial disparities may be widening within safety-net hospitals for non-HRRP-targeted conditions. https://www.clinicaladvisor.com/racial-disparities-may-have-widened-after-hospital-readmissions-program/article/825319/ Mon, 07 Jan 2019 14:00:00 GMT Racial disparities may be widening within safety-net hospitals for non-HRRP-targeted conditions. https://www.clinicaladvisor.com/racial-disparities-may-have-widened-after-hospital-readmissions-program/article/825319/ Compared with unscreened individuals, a colonoscopy with normal findings may be linked to lower risk of colorectal cancer deaths for more than 12 years. https://www.clinicaladvisor.com/negative-colonoscopy-findings-linked-to-lower-risk-of-colorectal-cancer-deaths/article/824842/ Fri, 04 Jan 2019 14:00:00 GMT Compared with unscreened individuals, a colonoscopy with normal findings may be linked to lower risk of colorectal cancer deaths for more than 12 years. https://www.clinicaladvisor.com/negative-colonoscopy-findings-linked-to-lower-risk-of-colorectal-cancer-deaths/article/824842/ Patients with type 2 diabetes treated with liraglutide experience a greater reduction in systolic BP if they have lower baseline continuous glucose monitoring values and higher diastolic BP. https://www.clinicaladvisor.com/reductions-in-systolic-bp-linked-to-weight-bmi-diastolic-bp-hba1c-in-type-2-diabetes/article/825027/ Fri, 04 Jan 2019 14:00:00 GMT Patients with type 2 diabetes treated with liraglutide experience a greater reduction in systolic BP if they have lower baseline continuous glucose monitoring values and higher diastolic BP. https://www.clinicaladvisor.com/reductions-in-systolic-bp-linked-to-weight-bmi-diastolic-bp-hba1c-in-type-2-diabetes/article/825027/ A study was conducted to assess the safety, tolerability, and efficacy of methyl estradiolpropanoate, a topical soft estrogen cosmeceutical for the treatment of estrogen-deficient skin. https://www.clinicaladvisor.com/treating-estrogen-deficient-skin-in-postmenopausal-women/article/825038/ Fri, 04 Jan 2019 14:00:00 GMT A study was conducted to assess the safety, tolerability, and efficacy of methyl estradiolpropanoate, a topical soft estrogen cosmeceutical for the treatment of estrogen-deficient skin. https://www.clinicaladvisor.com/treating-estrogen-deficient-skin-in-postmenopausal-women/article/825038/