CT - New in Testing

Mature and Immature Corneocyte Detection Force Distance Curves vs. Microfluorometry

Mon, 06 May 2013 06:17:30 GMT

Here, the author compares two methods to determine the maturity of corneocytes based on their cross-linking that could be used to evaluate the anti-aging effects of molecular agents. The first utilizes microfluorometry, while the second involves F-D curves generated via contact mode AFM. Both methods successfully detected differences in mature or immature corneocytes with 95% confidence.

Testing Tactics—Consumer vs. Scientific Language: Relating In vivo to In vitro

Mon, 06 May 2013 06:10:43 GMT

It should perhaps go without saying that consumer products are sold using consumer language. Market researchers and consumer scientists spend a great deal of time studying their target audience and learning this vocabulary, which subsequently allows the recounting of product benefits in the same terminology.

Researchers Develop Non-animal, Dendritic-based Sensitizer Test

Fri, 12 Apr 2013 06:42:40 GMT

Researchers from the University of Aveiro, the University of Coimbra and the University Hospital of Coimbra have developed a dendritic cell-based test for skin sensitizers that can serve as an alternative to animal testing.

Beiersdorf Researcher Develops Skin Imaging Method for Analysis

Tue, 09 Apr 2013 06:59:10 GMT

Beiersdorf has created a new method of skin analysis to help it develop new skin care products.

Hair Ethnicity and Ellipticity: A Preliminary Study

Thu, 04 Apr 2013 06:20:15 GMT

Ethnic hair care addresses diverse fiber compositions that require unique products. This comprehensive review in hair fiber dimensions among straight, wavy and curly/coily hair serves as a basis from which product developers can design products to cater to unique hair type needs. The current study examines the ellipticity of Caucasian, Brazilian, Hispanic and African-American hair.

Compass—Affinity to Water

Tue, 05 Mar 2013 06:38:10 GMT

While our path may appear to veer far from water, its status as the universal solvent will bring us back to the source.

A High Throughput Method to Predict Skin Penetration and Screen Topical Formulations

Tue, 05 Mar 2013 06:32:07 GMT

This work studies the applicability of a 96-well-based skin-mimetic artificial membrane permeability model to differentiate between topical pharmaceutical and cosmetic formulations. Results are compared with data obtained from in vitro Franz cell permeability measurements and reveal the applicability of this method to assess cosmetic formulation permeation and speed the discovery process.

Influence of Skin Diffuse Reflectance on Sun Damage and Ingredient Efficacy Measurements

Tue, 05 Mar 2013 06:21:16 GMT

Current in vitro methods to assess photostability and antioxidant activity do not account for the diffuse reflectance of skin. Described here is an in vitro test that addresses this variable, mimics end-use product conditions and models photodamage processes. The approach is employed to determine the efficacy of an antioxidant from the Camellia sinensis (tea) plant.

Adjusting Substrate/Product Interfacial Properties to Improve In vivo/In vitro SPF Correlation

Tue, 05 Mar 2013 05:49:44 GMT

This work evaluates the impact of a plasma treatment on test substrates to modify their surface energy, to more closely correlate in vitro SPF measurements with in vivo measurements—without chemically altering the test products. The authors chose the level of plasma modification to use on a substrate based on in vivo values; they explain how to choose it regarding specific formulas in a further paper.

The Effect of Skin Metabolism on the Absorption of Chemicals

Fri, 01 Feb 2013 08:58:05 GMT

Skin expresses enzymes that can metabolize endogenous molecules but little is known regarding how they impact the delivery of xenobiotics. This review of recent works shows that skin metabolism alters the dermal absorption of lipophilic compounds, which opens new areas of investigation regarding the safety and efficacy of topically applied cosmetics.

Cosmetics & Toiletries Adds Coty Sun Care Advisor

Wed, 16 Jan 2013 02:59:40 GMT

Cosmetics & Toiletries is pleased to welcome Marc Pissavini, PhD, to its prestigious Scientific Advisory Board. Pissavini began his career as an analytical chemist and in 1998, joined the sun research department of Coty-Lancaster in Monaco. Since 2008, he has served as the director of Basic and Applied Research for the company.

Consumer Perception of Fine Lines and Wrinkles Assessed by Qualitative Methods

Fri, 04 Jan 2013 06:43:37 GMT

There are varying definitions, associations and overall impressions of fine lines and wrinkles among different consumer segments. The findings of this study offer invaluable insight into consumers’ opinions, and by qualitative in-depth interviews, they provide a well-defined vernacular for aging descriptors. This language is critical for developmental research, consumer evaluation and marketing within the cosmetic industry.

Shiseido Develops Method Using Spectrometry to Display Skin Permeation

Thu, 03 Jan 2013 09:37:19 GMT

Shiseido has developed a method to assess the skin permeation of cosmetic ingredients using a novel spectrometry technology.

Peptide Microarray to Advance Product Development

Tue, 20 Nov 2012 08:23:09 GMT

Pepchipomics is a new project supported by the FP7 of the European Union aimed at synthesizing and reading high-density peptide microarrays, resulting in a new high-throughput platform that integrates peptide synthesis, detection and analysis at an unprecedented scale.

Appointment of Commissioner Borg May Jeopardize Animal-alternative Test Progress

Tue, 20 Nov 2012 05:45:18 GMT

Cosmetics Europe recently urged the industry to oppose the appointment of Tonio Borg as Health Commissioner, as his "commitment to conclude the introduction of the March 2013 [animal testing] ban without addressing scientific reality or consumer needs is a great concern."

Determining Korean Consumers’ Degree of Exposure to Lipstick and Face Creams

Tue, 06 Nov 2012 06:12:30 GMT

This study describes methods used in a Korean study to calculate consumer exposure to lipstick and face creams. The average amount applied daily was estimated and compared with data collected by weighing containers before and after use. The data collected was 1.8 to 1.6 times greater than the estimate, so although the survey represented real use patterns, the actual data was more accurate.

'Land'scaping-Ho!

Thu, 01 Nov 2012 08:53:45 GMT

For the current picture, Cosmetics & Toiletries knows many of the headaches you endure; for example, regulations and scale-up. It would take volumes to address all the challenges these pose, but this issue covers two specific aspects of them.

‘How Did THAT Get in There?’ Identifying Particulate Contamination in Products and Packaging

Thu, 01 Nov 2012 07:47:28 GMT

Particulate contamination and discoloration may occur in products due to foreign materials introduced via raw materials or during the manufacturing process. Agglomeration or reactions between ingredients and packaging components also are possible sources. The identification of contaminants and their origin, described here, is therefore critical so that future incidents can be prevented and safety or regulatory concerns can be addressed.

Determining Korean Consumers’ Degree of Exposure to Lipstick and Face Creams

Thu, 01 Nov 2012 07:30:21 GMT

Stem Cells, Wellness and Claims Substantiation Take Center Stage at IFSCC Congress

Wed, 24 Oct 2012 08:36:20 GMT

The 2012 IFSCC Congress opened with a frenzy; the "African Frenzy" dancers, that is, and enlightened attendees over three days with 65+ presentations and more than 150 posters.