MyVisionTest

Mitochondrial DNA and AMD

Fri, 26 Jun 2009 00:00:00 CDT

A new study finds that the mitochondrial (mt)DNA in the retinas of patients with age-related macular degeneration (AMD) contained more single-nucleotide polymorphisms (SNPs) within the control region of the geneome compared to normal retinas. There was an increased frequency of mtDNA SNPs...

The vitreous in AMD

Thu, 25 Jun 2009 00:00:00 CDT

A new study finds that vitreomacular adhesion (VMA) is a risk factor for exudative age-related macular degeneration (AMD), and posterior vitreous detachment (PVD) may protect against exudative AMD. The cause of choroidal neovascularization (CNV) in exudative AMD is not fully understood,...

VEGF genotype associated with retinal angiomatous proliferation

Thu, 25 Jun 2009 00:00:00 CDT

A new study finds that VEGF haplotype 1-6 has a strong effect on the risk of developing retinal angiomatous proliferation (RAP). Retinal angiomatous proliferation is a distinct form of neovascular age-related macular degeneration (AMD) associated with angiomatous proliferation that originates...

Endophthalmitis after anti-VEGF injections

Wed, 24 Jun 2009 00:00:00 CDT

A new study reporting on the largest series of presumed endophthalmitis cases following intravitreal anti-VEGF injection published to date finds an incidence of 0.049%, and that 20% of cases have a very poor visual outcome. Endophthalmitis is the most dreaded complication of intravitreal...

The inner segment-outter segment line on SD-OCT correlates with visual outcome following PDT

Tue, 23 Jun 2009 00:00:00 CDT

A retrospective review of Japanese patients with neovascular age-related macular degeneration (AMD) finds that the integrity of the inner segment-outter segment line on spectral-domain optical coherence tomography (SD-OCT) correlates with final visual acuity following successful photodynamic...

AMD-related polypoidal choroidal vasculopathy responsible for anti-VEGF treatment failure

Tue, 23 Jun 2009 00:00:00 CDT

A new study reports that polypoidal choroidal vasculopathy (PCV) is a common cause of Lucentis (ranibizumab) and Avastin (bevacizumab) failure in the treatment of neovascular age-related macular degeneration (AMD). Intravitreal Lucentis and Avastin injections are highly effective in the...