NCI Clinical Trial Results

Denosumab Keeps Bones Strong during Prostate Cancer Treatment

Wed, 28 Oct 2009 04:00:00 GMT

Treatment with the monoclonal antibody denosumab increased bone mineral density (BMD) and reduced the risk of fractures in men who received a common treatment for prostate cancer that had not spread to other parts of the body, according to the results of a large, placebo-controlled clinical trial published in the August 20 New England Journal of Medicine.

Modified Chemotherapy Regimen Effective in Advanced Ovarian Cancer

Wed, 07 Oct 2009 04:00:00 GMT

Women with advanced ovarian cancer had delayed disease progression and lived longer after receiving a modified regimen of a standard chemotherapy drug combination, according to an article published online Sept. 20, 2009, in The Lancet.

Weight Lifting Does Not Exacerbate and May Improve Lymphedema Symptoms After Breast Cancer

Wed, 16 Sep 2009 04:00:00 GMT

Slowly progressive weight lifting did not aggravate limb swelling among breast cancer survivors with lymphedema, according to a randomized clinical trial in the August 13, 2009, issue of The New England Journal of Medicine.

Donated Stem Cell Transplants Better than Self-transplants for Most Patients with AML

Thu, 23 Jul 2009 04:00:00 GMT

Evidence from a meta-analysis of prospective clinical trials supports the use of donated (or allograft) stem cell transplants to treat most individuals with acute myeloid leukemia, according to the June 10, 2009, Journal of the American Medical Association.

For Children with Leukemia, Radiation May Be Unnecessary

Thu, 23 Jul 2009 04:00:00 GMT

Children with the most common form of leukemia can safely forego radiation therapy to prevent relapse if they are treated with chemotherapy regimens tailored to their individual needs, according to the June 25, 2009, New England Journal of Medicine.

Radiofrequency Ablation Effective Against Barrett Esophagus

Thu, 23 Jul 2009 04:00:00 GMT

In a randomized phase II trial, radiofrequency ablation led to high rates of eradication of the cell abnormalities associated with Barrett esophagus, according to the May 28, 2009, New England Journal of Medicine.

Treatment Regimen Extends Survival for Women with Cervical Cancer

Mon, 29 Jun 2009 04:00:00 GMT

Patients with locally advanced cervical cancer who received gemcitabine (Gemzar®) both as part of initial treatment and as part of therapy following primary treatment had improved survival compared with patients whose treatment did not include gemcitabine, according to findings presented at the 2009 ASCO meeting in Orlando.

HPV Status Can Predict Outcome in Oropharyngeal Cancer

Fri, 19 Jun 2009 04:00:00 GMT

Patients with advanced oropharyngeal cancer are more likely to survive if their tumors are HPV positive than if they are HPV negative, according to findings presented at the 2009 ASCO meeting in Orlando.

Early Chemotherapy to Prevent Ovarian Cancer Recurrence Fails to Increase Survival

Fri, 19 Jun 2009 04:00:00 GMT

Women in remission for ovarian cancer who started chemotherapy to prevent a recurrence based on blood levels of the protein CA125 did not live longer than women who started chemotherapy only after symptoms of the disease arose, according to findings presented at the 2009 ASCO meeting in Orlando.

Breast Cancer Drug Helps Patients with Gastric Cancer

Fri, 19 Jun 2009 04:00:00 GMT

Patients with advanced gastric cancer who received standard chemotherapy plus trastuzumab (Herceptin®) survived several months longer than those who received chemotherapy alone, according to findings presented at the 2009 ASCO meeting in Orlando.