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Study published in Neuro-Oncology shows brain tumor eradication and prolonged survival

T. D — Fri, 03 Feb 2012 21:05:47 +0000

Study conducted in mice treated with Toca 511 and 5-FC Tocagen Inc. today announced the publication of data showing the company’s investigational treatment for high grade glioma eradicates brain tumors and provides a dramatic survival benefit in mouse models of glioblastoma. Almost all mice receiving the top dose of Toca 511 followed by 5-FC were [...]

DNA Test that Identifies Down Syndrome in Pregnancy Can Also Detect Trisomy 18 and Trisomy 13

Neuroscience News — Fri, 03 Feb 2012 05:28:17 +0000

A newly available DNA-based prenatal blood test that can identify a pregnancy with Down syndrome can also identify two additional chromosome abnormalities: trisomy 18 (Edwards syndrome) and trisomy 13 (Patau syndrome).The test for all three defects can be offered as early as 10 weeks of pregnancy to women who have been identified as being at [...]

Patients’ Brains May Adapt to ADHD Medication

Neuroscience News — Thu, 02 Feb 2012 19:36:29 +0000

New research reveals how the brain appears to adapt to compensate for the effects of long-term ADHD medication, suggesting why ADHD medication is more effective short-term than it is long-term. The study, from the Institute of Psychiatry (IoP) at King’s College London is published today in the American Journal of Psychiatry. Dr Paolo Fusar-Poli and [...]

Gene Regulator in Brain’s Executive Hub Tracked Across Lifespan

Neuroscience News — Thu, 02 Feb 2012 19:00:22 +0000

Mental illness suspect genes are among the most environmentally responsive. For the first time, scientists have tracked the activity, across the lifespan, of an environmentally responsive regulatory mechanism that turns genes on and off in the brain’s executive hub. Among key findings of the study by National Institutes of Health scientists: genes implicated in schizophrenia [...]

Same Genes Linked to Early- and Late-Onset Alzheimer’s Disease

Neuroscience News — Thu, 02 Feb 2012 00:22:16 +0000

The same gene mutations linked to inherited, early-onset Alzheimer’s disease have been found in people with the more common late-onset form of the illness. The discovery by researchers at Washington University School of Medicine in St. Louis may lead doctors and researchers to change the way Alzheimer’s disease is classified. They report their findings Feb. [...]

Obesity Reduces the Size of Your Brain

Neuroscience News — Wed, 01 Feb 2012 20:23:31 +0000

New research from Uppsala University shows that a specific brain region linked to appetite regulation is reduced in elderly people who are obese. Poor eating habits over a lifetime may therefore weaken brain function that helps us to control our desire to eat. The findings are published in The International Journal of Obesity. Researchers Samantha [...]

Scientists Turn Skin Cells Into Neural Precursors, Bypassing Stem Cell Stage

Neuroscience News — Wed, 01 Feb 2012 06:27:36 +0000

Mouse skin cells can be converted directly into cells that become the three main parts of the nervous system, according to researchers at the Stanford University School of Medicine. The finding is an extension of a previous study by the same group showing that mouse and human skin cells can be directly converted into functional [...]

Scientists Decode Brain Waves to Eavesdrop on What We Hear

Neuroscience News — Wed, 01 Feb 2012 03:14:46 +0000

Neuroscientists may one day be able to hear the imagined speech of a patient unable to speak due to stroke or paralysis, according to University of California, Berkeley, researchers. These scientists have succeeded in decoding electrical activity in the brain’s temporal lobe – the seat of the auditory system – as a person listens to [...]

Gene Mutation in Autism Found to Cause Hyperconnectivity in Brain’s Hearing Center

Neuroscience News — Tue, 31 Jan 2012 22:41:30 +0000

Hyperconnectivity triggered by loss of PTEN gene can be blocked by treatment with rapamycin. New research from Cold Spring Harbor Laboratory (CSHL) might help explain how a gene mutation found in some autistic individuals leads to difficulties in processing auditory cues and paying spatial attention to sound. The study has found that when a suspected [...]

Short-term Memory is Based on Synchronized Brain Oscillations

Neuroscience News — Tue, 31 Jan 2012 21:46:45 +0000

Scientists have now discovered how different brain regions cooperate during short-term memory. Holding information within one’s memory for a short while is a seemingly simple and everyday task. We use our short-term memory when remembering a new telephone number if there is nothing to write at hand, or to find the beautiful dress inside the [...]