http://feeds.feedburner.com/runurology Latest articles from Renal and Urology News Urology Urology Urology custserv@haymarketmedia.com no New tool promises to help patients decide whether radical prostatectomy or radiation therapy is their best treatment option. https://www.renalandurologynews.com/prostate-cancer-care-may-be-personalized-with-novel-online-calculator/article/836620/ Wed, 27 Feb 2019 20:16:49 GMT New tool promises to help patients decide whether radical prostatectomy or radiation therapy is their best treatment option. https://www.renalandurologynews.com/prostate-cancer-care-may-be-personalized-with-novel-online-calculator/article/836620/ Findings from a small study suggest it could be an effective, safe, and attractive alternative to fluoroquinolones, bacterial resistance to which is becoming increasingly prevalent. https://www.renalandurologynews.com/fosfomycin-promising-for-chronic-bacterial-prostatitis/article/836193/ Wed, 27 Feb 2019 12:00:00 GMT Findings from a small study suggest it could be an effective, safe, and attractive alternative to fluoroquinolones, bacterial resistance to which is becoming increasingly prevalent. https://www.renalandurologynews.com/fosfomycin-promising-for-chronic-bacterial-prostatitis/article/836193/ Investigators observe higher rates of clinical cure or microbiologic eradication in patients treated with plazomicin vs meropenem, including those with infections due to Enterobacteriaceae not susceptible to aminoglycosides. https://www.renalandurologynews.com/plazomicin-vs-meropenem-for-complicated-urinary-tract-infections/article/835608/ Fri, 22 Feb 2019 12:17:47 GMT Investigators observe higher rates of clinical cure or microbiologic eradication in patients treated with plazomicin vs meropenem, including those with infections due to Enterobacteriaceae not susceptible to aminoglycosides. https://www.renalandurologynews.com/plazomicin-vs-meropenem-for-complicated-urinary-tract-infections/article/835608/ This survey assessed the opinions of oncologists, urologists, and oncology nurses on the use of shared decision-making in older men with metastatic castration-resistant prostate cancer. https://www.renalandurologynews.com/use-of-shared-decision-making-in-elderly-with-mcrpc/article/834955/ Wed, 20 Feb 2019 12:00:00 GMT This survey assessed the opinions of oncologists, urologists, and oncology nurses on the use of shared decision-making in older men with metastatic castration-resistant prostate cancer. https://www.renalandurologynews.com/use-of-shared-decision-making-in-elderly-with-mcrpc/article/834955/ Median metastasis-free survival was longer with darolutamide than with placebo: 40.4 vs 18.4 months. https://www.renalandurologynews.com/darolutamide-improves-metastasis-free-survival-in-crpc/article/833883/ Thu, 14 Feb 2019 21:50:00 GMT Median metastasis-free survival was longer with darolutamide than with placebo: 40.4 vs 18.4 months. https://www.renalandurologynews.com/darolutamide-improves-metastasis-free-survival-in-crpc/article/833883/ In a "real world" study, biopsy and surgical grade groups 2, 3, 4, and 5 each were associated with incrementally higher risks for adverse pathologic features and biochemical recurrence. https://www.renalandurologynews.com/pca-grade-group-better-predicts-pathologic-outcomes-recurrence/article/834162/ Thu, 14 Feb 2019 14:11:04 GMT In a "real world" study, biopsy and surgical grade groups 2, 3, 4, and 5 each were associated with incrementally higher risks for adverse pathologic features and biochemical recurrence. https://www.renalandurologynews.com/pca-grade-group-better-predicts-pathologic-outcomes-recurrence/article/834162/ A high percentage of men with prostate cancer have 1 or more potentially pathogenic germline variants, but would not be eligible for mutation testing under current NCCN guidelines. https://www.renalandurologynews.com/prostate-cancer-current-guidelines-germline-genetic-testing-insufficient/article/833790/ Wed, 13 Feb 2019 12:00:00 GMT A high percentage of men with prostate cancer have 1 or more potentially pathogenic germline variants, but would not be eligible for mutation testing under current NCCN guidelines. https://www.renalandurologynews.com/prostate-cancer-current-guidelines-germline-genetic-testing-insufficient/article/833790/ From 2010 to 2015, active surveillance/watchful waiting increased from 14.5% to 42.1%, according to a new study. https://www.renalandurologynews.com/prostate-cancer-active-surveillance-increasing-in-the-us/article/832957/ Tue, 12 Feb 2019 12:00:00 GMT From 2010 to 2015, active surveillance/watchful waiting increased from 14.5% to 42.1%, according to a new study. https://www.renalandurologynews.com/prostate-cancer-active-surveillance-increasing-in-the-us/article/832957/ In a small study, men on androgen deprivation therapy for prostate cancer lost weight and experienced improved hemoglobin A1C and lipid profiles. https://www.renalandurologynews.com/low-carbohydrate-diet-plus-walking-may-ease-adverse-effects-of-prostate-cancer-hormone-therapy/article/832565/ Fri, 08 Feb 2019 12:30:00 GMT In a small study, men on androgen deprivation therapy for prostate cancer lost weight and experienced improved hemoglobin A1C and lipid profiles. https://www.renalandurologynews.com/low-carbohydrate-diet-plus-walking-may-ease-adverse-effects-of-prostate-cancer-hormone-therapy/article/832565/ Men with advanced disease report health-related quality of life similar to that of those with localized disease. https://www.renalandurologynews.com/good-quality-of-life-reported-even-in-advanced-prostate-cancer/article/832564/ Thu, 07 Feb 2019 11:45:00 GMT Men with advanced disease report health-related quality of life similar to that of those with localized disease. https://www.renalandurologynews.com/good-quality-of-life-reported-even-in-advanced-prostate-cancer/article/832564/ Squamous cell carcinoma is associated with a 79% increased risk of death compared with urothelial carcinoma in patients with muscle-invasive bladder cancer, study finds. https://www.renalandurologynews.com/muscle-invasive-bladder-cancer-histology-predicts-survival/article/831027/ Tue, 05 Feb 2019 12:00:00 GMT Squamous cell carcinoma is associated with a 79% increased risk of death compared with urothelial carcinoma in patients with muscle-invasive bladder cancer, study finds. https://www.renalandurologynews.com/muscle-invasive-bladder-cancer-histology-predicts-survival/article/831027/ Weight loss in the first year after starting androgen deprivation therapy in men who have undergone radical surgery for prostate cancer ups the risk of metastatic disease and death from prostate cancer. https://www.renalandurologynews.com/prostate-cancer-death-risk-higher-with-first-year-post-adt-weight-loss/article/831727/ Mon, 04 Feb 2019 14:00:00 GMT Weight loss in the first year after starting androgen deprivation therapy in men who have undergone radical surgery for prostate cancer ups the risk of metastatic disease and death from prostate cancer. https://www.renalandurologynews.com/prostate-cancer-death-risk-higher-with-first-year-post-adt-weight-loss/article/831727/ Study finds 18 vs 6 months of androgen suppression and radiotherapy for locally advanced prostate cancer is associated with a 30% decreased risk of death from the disease. https://www.renalandurologynews.com/longer-androgen-suppression-with-radiotherapy-superior-for-advanced-prostate-cancer/article/830993/ Mon, 04 Feb 2019 12:00:00 GMT Study finds 18 vs 6 months of androgen suppression and radiotherapy for locally advanced prostate cancer is associated with a 30% decreased risk of death from the disease. https://www.renalandurologynews.com/longer-androgen-suppression-with-radiotherapy-superior-for-advanced-prostate-cancer/article/830993/ Kidney cancer and some other cancers tied to obesity are increasing the most rapidly among individuals younger than 50. https://www.renalandurologynews.com/obesity-related-cancers-rising-among-younger-adults/article/830985/ Mon, 04 Feb 2019 12:00:00 GMT Kidney cancer and some other cancers tied to obesity are increasing the most rapidly among individuals younger than 50. https://www.renalandurologynews.com/obesity-related-cancers-rising-among-younger-adults/article/830985/ In a study of men with nonmetastatic high-risk prostate cancer who have rising PSA after primary therapy, investigators found no significant difference in PSA progression-free survival. https://www.renalandurologynews.com/prostate-cancer-patients-may-not-benefit-from-adding-docetaxel-to-adt/article/830387/ Thu, 31 Jan 2019 16:00:00 GMT In a study of men with nonmetastatic high-risk prostate cancer who have rising PSA after primary therapy, investigators found no significant difference in PSA progression-free survival. https://www.renalandurologynews.com/prostate-cancer-patients-may-not-benefit-from-adding-docetaxel-to-adt/article/830387/ Androgen deprivation therapy recipients had a significantly lower risk for autoimmune diseases overall and for Graves' disease, uveitis, and psoriasis. https://www.renalandurologynews.com/prostate-cancer-adt-may-reduce-autoimmune-disease-risk/article/830414/ Thu, 31 Jan 2019 11:45:00 GMT Androgen deprivation therapy recipients had a significantly lower risk for autoimmune diseases overall and for Graves' disease, uveitis, and psoriasis. https://www.renalandurologynews.com/prostate-cancer-adt-may-reduce-autoimmune-disease-risk/article/830414/ First-line treatment of metastatic renal cell carcinoma with tyrosine kinase inhibitors is associated with worse progression-free and overall survival in patients with non-clear-cell vs clear-cell histology. https://www.renalandurologynews.com/first-line-tki-outcomes-worse-in-non-clear-cell-kidney-cancer/article/829774/ Wed, 30 Jan 2019 12:00:00 GMT First-line treatment of metastatic renal cell carcinoma with tyrosine kinase inhibitors is associated with worse progression-free and overall survival in patients with non-clear-cell vs clear-cell histology. https://www.renalandurologynews.com/first-line-tki-outcomes-worse-in-non-clear-cell-kidney-cancer/article/829774/ Men with unfavorable-risk prostate cancer who had a detectable PSA nadir and a time to PSA nadir less than 12 months had a 5-fold increased risk of dying from their disease. https://www.renalandurologynews.com/post-radiotherapy-time-to-psa-nadir-predicts-prostate-cancer-mortality/article/829771/ Tue, 29 Jan 2019 12:15:00 GMT Men with unfavorable-risk prostate cancer who had a detectable PSA nadir and a time to PSA nadir less than 12 months had a 5-fold increased risk of dying from their disease. https://www.renalandurologynews.com/post-radiotherapy-time-to-psa-nadir-predicts-prostate-cancer-mortality/article/829771/ Five-year rates of biopsy progression-free, treatment-free, and cancer-specific survival are similar for men younger than 60 and those aged 60 and older when placed on active surveillance. https://www.renalandurologynews.com/prostate-cancer-active-surveillance-is-a-viable-option-for-men-younger-than-60/article/829682/ Mon, 28 Jan 2019 12:30:00 GMT Five-year rates of biopsy progression-free, treatment-free, and cancer-specific survival are similar for men younger than 60 and those aged 60 and older when placed on active surveillance. https://www.renalandurologynews.com/prostate-cancer-active-surveillance-is-a-viable-option-for-men-younger-than-60/article/829682/ Negative findings on a confirmatory fusion biopsy are associated with a lower risk of Grade Group progression. https://www.renalandurologynews.com/negative-fusion-biopsy-in-prostate-cancer-active-surveillance-predicts-lower-progression-risk/article/829488/ Fri, 25 Jan 2019 15:04:19 GMT Negative findings on a confirmatory fusion biopsy are associated with a lower risk of Grade Group progression. https://www.renalandurologynews.com/negative-fusion-biopsy-in-prostate-cancer-active-surveillance-predicts-lower-progression-risk/article/829488/