https://www.science.org/journal/science Science! http://www.rssboard.org/rss-specification python-feedgen https://feeds.science.org/images/science-144sq.png https://www.science.org/journal/science en Mon, 31 Aug 2026 18:41:09 +0000 https://www.science.org/content/article/dreams-making-drugs-and-tissues-space-get-closer-reality Maturing techniques and cheaper launches fuel microgravity research—and hopes of orbital manufacturing https://www.science.org/content/article/dreams-making-drugs-and-tissues-space-get-closer-reality Thu, 27 Aug 2026 15:00:00 -0400 https://www.science.org/content/article/climate-change-strengthening-el-niño-coral-records-suggest 1000-year archive from the Galápagos portends greater weather disruptions from the Pacific climate cycle https://www.science.org/content/article/climate-change-strengthening-el-niño-coral-records-suggest Thu, 27 Aug 2026 15:00:00 -0400 https://www.science.org/doi/10.1126/science.aeh7112 Inflammatory bowel disease (IBD) is a chronic condition caused by altered cytokine signaling, maladaptive immunity, dysbiosis, and intestinal barrier dysfunction. Although current therapies aim to correct these imbalances to induce remission, most ... https://www.science.org/doi/10.1126/science.aeh7112 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.aed9893 Foreshock activity is a key consideration in traffic-light protocol (TLP) to mitigate seismic risk from injection-induced earthquakes (IIEs). However, the seismogenic processes of IIE foreshocks remain poorly understood. Using an enhanced western Canada ... https://www.science.org/doi/10.1126/science.aed9893 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.aec3449 Sex chromosome evolution is among the most dynamic genomic innovations in vertebrates, yet why some lineages evolve XY while others evolve ZW remains unclear. Using chromosome-level genomes from 19 geckos, we found that gecko sex chromosomes originated ... https://www.science.org/doi/10.1126/science.aec3449 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.ady4523 Systematic mapping of protein-protein interaction (PPI) networks and determining how causal mutations rewire them in autism spectrum disorder (ASD) provide a powerful framework for uncovering disease mechanisms and therapeutic opportunities. Using ... https://www.science.org/doi/10.1126/science.ady4523 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.ael0147 When I was a postdoctoral researcher, I spent several years teaching at an interdisciplinary research institute in Vienna, Austria. There, my main course sought to train master’s students—mostly biologists and veterinarians—to write a philosophical reflection on some aspect of the comparative cognition studies they were running. https://www.science.org/doi/10.1126/science.ael0147 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.aeh4856 Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce mortality in heart failure, but their pharmacological target remains unclear. In this study, we showed that SGLT2i directly activate pantothenate kinase 1 (PANK1), the rate-limiting enzyme in ... https://www.science.org/doi/10.1126/science.aeh4856 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.aef8268 In this work, we tackled the long-standing challenge of the massive computation for hyperspectral imaging that is required to reconstruct and process large-volume spatial-spectral data cubes. Specifically, we designed a hardware accelerator, fabricated ... https://www.science.org/doi/10.1126/science.aef8268 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.aeg8955 Tin halide perovskite light-emitting diodes (PeLEDs) offer promise due to their solution processability and low toxicity, yet low efficiency and poor stability hinder practical use. We found that electroluminescence failure in CsSnI3 is primarily driven ... https://www.science.org/doi/10.1126/science.aeg8955 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.ael7895 Editors’ selections from the current scientific literature https://www.science.org/doi/10.1126/science.ael7895 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.ael7894 Highlights from the Science family of journals https://www.science.org/doi/10.1126/science.ael7894 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.aef0464 Correction of selective assumptions and inconsistent interpretations of evidence would overturn policy justification https://www.science.org/doi/10.1126/science.aef0464 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.aej9417 An ongoing public health crisis is unfolding in El Obeid, the capital of Sudan’s North Kordofan, where a protracted proxy war between the Sudanese Armed Forces (SAF) and the paramilitary Rapid Support Forces (RSF) has led to civilian casualties, infrastructure collapse, and mass displacement, leading to overcrowding in sites of refuge that increases the risk of infectious disease outbreaks. This health crisis will not follow the path of a traditional disease outbreak because it is complicated by the severe humanitarian and human rights violations unfolding concurrently (1). https://www.science.org/doi/10.1126/science.aej9417 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.aek8173 In June 2026, the southern margin of the Taklamakan Desert experienced an unprecedented extreme precipitation event, triggering sudden and severe flooding (1). The phenomenon of desert flooding challenges the conventional understanding of hydrological processes in hyperarid regions, where flooding events have traditionally been considered rare. However, this perception is increasingly challenged by observational evidence. https://www.science.org/doi/10.1126/science.aek8173 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.aek5038 HomeScienceVol. 393, No. 6814Deep-sea mining outpaces both science and lawBack To Vol. 393, No. 6814 Full accessLetter Share on Deep-sea mining outpaces both science and lawAlejandro Olivera, Erick Morales-Montes de Oca, [...] , Viridiana Lázaro, María Fernanda Méndez-Martínez, and Héctor Reyes-Bonilla+2 authors fewerAuthors Info & AffiliationsScience27 Aug 2026Vol 393, Issue 6814p. 867DOI: 10.11… https://www.science.org/doi/10.1126/science.aek5038 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.ael0871 HomeScienceVol. 393, No. 6814M.S. Swaminathan: The Man Who Fed IndiaBack To Vol. 393, No. 6814 Full accessBooks et al.Podcast Share on M.S. Swaminathan: The Man Who Fed IndiaScience27 Aug 2026Vol 393, Issue 6814p. 866DOI: 10.1126/science.ael0871 PREVIOUS ARTICLEThe history and future of sickle cell diseasePreviousNEXT ARTICLEDeep-sea mining outpaces both science and lawNext NotificationsBookmark… https://www.science.org/doi/10.1126/science.ael0871 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.aej0154 Promising new gene therapies have arrived, but it is too soon to claim a medical victory https://www.science.org/doi/10.1126/science.aej0154 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.aeh4348 Can the skin microbiome shape healthy aging? https://www.science.org/doi/10.1126/science.aeh4348 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.aek3835 New transfer RNA medicines require redesigned lipid nanoparticles for delivery https://www.science.org/doi/10.1126/science.aek3835 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.aek4631 Van der Waals interaction guides the growth of single-crystal metals on two-dimensional semiconductors https://www.science.org/doi/10.1126/science.aek4631 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.aek4499 Artificial intelligence enables the design of RNA pseudoknots https://www.science.org/doi/10.1126/science.aek4499 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.aej2018 The Iran war could serve as a turning point in accelerating the global transition away from fossil fuels: Every additional day that oil and gas prices are high and future supplies are uncertain, wind and solar power—cheaper and more scalable than ever ... https://www.science.org/doi/10.1126/science.aej2018 Thu, 27 Aug 2026 09:01:00 -0400 https://www.science.org/content/article/nasa-s-roman-telescope-readies-sweeping-view-universe With a view 100 times larger than Hubble, the observatory will survey the cosmos for distant worlds and clues to dark energy https://www.science.org/content/article/nasa-s-roman-telescope-readies-sweeping-view-universe Wed, 26 Aug 2026 14:45:00 -0400 https://www.science.org/content/article/worldwide-study-diseases-gets-historic-funding-influx Gates Foundation pledges $540 million to a project often criticized for its opacity https://www.science.org/content/article/worldwide-study-diseases-gets-historic-funding-influx Tue, 25 Aug 2026 17:30:00 -0400 https://www.science.org/content/article/neurologist-antivaccine-views-lead-nih-s-child-health-institute Appointment of John Gaitanis increases concern that scientific qualifications are no longer driving leadership picks https://www.science.org/content/article/neurologist-antivaccine-views-lead-nih-s-child-health-institute Fri, 21 Aug 2026 19:05:00 -0400 https://www.science.org/content/article/deadly-tick-borne-virus-gains-ground-europe-climate-warms Kosovo shows how surveillance can uncover hidden circulation—and help countries prepare before human cases appear https://www.science.org/content/article/deadly-tick-borne-virus-gains-ground-europe-climate-warms Fri, 21 Aug 2026 15:35:00 -0400 https://www.science.org/doi/10.1126/science.aef8874 Admixture between modern humans and extinct hominins has shaped the genomes of present-day individuals, but reconstructing this history has been constrained by the scarcity of archaic samples and unadmixed outgroup populations. We introduce TRACE, a ... https://www.science.org/doi/10.1126/science.aef8874 Thu, 30 Jul 2026 09:01:00 -0400 https://www.science.org/doi/10.1126/science.aec2171 Thalamocortical projections shape the functional regionalization and parallel sensory computations across the mammalian cortex. However, the principles of thalamocortical computations in nonmammalian vertebrates remain underexplored. In this work, we ... https://www.science.org/doi/10.1126/science.aec2171 Thu, 02 Jul 2026 09:01:00 -0400