Skin Deep - Clinical & Cosmetic Dermatology Blog

Psoriasis Treatments Among Hot Topics at AAD Meeting

2017-02-28T20:58:00.001-05:00

Psoriasis Treatments Among Hot Topics at AAD Meeting:

First-line therapies for moderate to severe psoriasis, the value of vitamin D, and the link between skin disease and problems with other organs will be among the topics covered at the conference.

Medscape Medical News

Mnenomic to Cut False Diagnoses of Recluse Spider Bites

2017-02-26T18:43:00.000-05:00

Mnenomic to Cut False Diagnoses of Recluse Spider Bites:

A simple mnemonic can help avoid false diagnosis of recluse spider bites, which has been mistaken for up to 40 other medical conditions, according to three U.S. researchers.

Reuters Health Information

Study Calls Into Question Sunscreen in Melanoma Prevention

2016-11-07T20:35:00.001-05:00

Sunscreen might not be protective against skin cancer, according to a study that used new moles as a marker of melanoma risk in children, but the newer broad-spectrum products could be more effective.
Medscape Medical News

By

Read More....

Functional annotation of putative conserved proteins from Borrelia burgdorferi to find potential drug targets

2016-11-05T21:03:00.001-04:00

The spirochete Borrelia burgdorferi is causative agent of Lyme disease. We have used various bioinformatics tools for predicting the function of unknown proteins present in B. burgdorferi's genome. While analysing the proteome data of B. burgdorferi, we have found 819 proteins. Out of these, 241 proteins are conserved hypothetical proteins (HPs), i.e., proteins of unspecified structures and biochemical functions. We have successfully annotated 120 HPs, and their corresponding functions have been predicted using different tools. On the basis of predicted functions, we have divided them into functional classes. Annotation and identification of functionally important regions in HPs from B. burgdorferi will enhance our understanding of new functional proteins, virulence mechanism and adaptability in host system.

By Shama Khan; Mohammad Sarwar Jamal; Farah Anjum; Mahmood Rasool; Abulaish Ansari; Asimul Islam; Faizan Ahmad; Md. Imtaiyaz Hassan in International Journal of Computational Biology and Drug Design (IJCBDD), 2016 Vol. 9 No. 4, pp. 295 - 318

Read More....

Interventional treatments for Hailey–Hailey disease

2016-10-13T20:48:00.001-04:00

Hailey–Hailey disease or familial benign chronic pemphigus is a rare blistering dermatosis that is characterized by recurrent erythematous plaques with a predilection for the skin folds. For extensive Hailey–Hailey disease that is recalcitrant to conventional therapy, laser ablation, photodynamic therapy, electron beam radiotherapy, botulinum toxin type A, dermabrasion, glycopyrrolate, and afamelanotide have been reported as useful treatments, but comparative trials are lacking. This review discusses the various treatment modalities for Hailey–Hailey disease and a summary of the evidence for the most recommended treatments.

By Benjamin Farahnik, Collin M. Blattner, Michael B. Mortazie, Benjamin M. Perry, William Lear, Dirk M. Elston

Read More....

Trends in tickborne diseases

2016-10-10T19:29:00.001-04:00

Tickborne diseases are a significant health problem in the United States with over 40,000 confirmed or probable cases reported as recently as 2014. Almost 80% of these cases consist of Lyme disease, but other diseases, including viral infections, are present and have been increasing in number over the past 20 years. Experts in tickborne diseases share updates about what’s new and what’s changing in the detection and transmission of these diseases.

By

Read More....

Nearly 50% Reduction in Diabetic Foot Ulcers With Stem Cells

2016-10-01T20:01:00.001-04:00

Injection of autologous mesenchymal stem cells into diabetic foot ulcers that did not respond to standard of care and offloading resulted in a 50% reduction in ulcer size at 6 weeks in a pilot study.
Medscape Medical News

By

Read More....

Who detects melanoma? Impact of detection patterns on characteristics and prognosis of patients with melanoma

2016-09-16T21:49:00.001-04:00

Despite the importance of early diagnosis, patients with cutaneous melanoma often seek consultation at advanced stages of the disease. The impact on prognosis according to who first detects the primary tumor has not been established.

By José Antonio Avilés-Izquierdo, Irene Molina-López, Enrique Rodríguez-Lomba, Ivan Marquez-Rodas, Ricardo Suarez-Fernandez, Pablo Lazaro-Ochaita

Read More....

Randomized placebo control study of insulin sensitizers (Metformin and Pioglitazone) in psoriasis patients with metabolic syndrome (Topical Treatment Cohort)

2016-08-23T12:30:00.001-04:00

Increased prevalence of metabolic syndrome (MS) is observed in psoriasis. Metformin has shown improvement in cardiovascular risk factors while pioglitazone demonstrated anti proliferative, anti-inflammatory an...

By Surjit Singh and Anil Bhansali

Read More....

Computer-aided classification of melanocytic lesions using dermoscopic images: Low reported accuracy for reader study on melanomas with low melanoma in situ to invasive melanoma ratio

2016-08-22T20:30:00.001-04:00

To the Editor: The report by Ferris et al1 represents a milestone in comparison of human and computer performance in melanoma detection. The receiver operating characteristic (ROC) curve analysis portrays the sensitivity-specificity tradeoff inherent in any diagnostic system. The study includes nonmelanocytic lesions, representing the clinical situation better than most previous computer-aided diagnostic studies.

By Bryce Schumacher, Nabin K. Mishra, Stephen W. Dusza, Allan C. Halpern, William V. Stoecker

Read More....

Screening for psoriatic arthritis using the PEST questionnaire: examining the optimal cutoff

2016-08-14T16:22:00.001-04:00

Abstract

With great interest we read the recently published article in this journal by Laura Coates et al(1). Indeed, early detection of psoriatic arthritis (PsA) in patients with psoriasis is necessary to adequately treat concomitant joint disease, which can significantly impact quality of life(2,3).

By E.F.A. Leijten, V. Sigurdsson, M.H. Wenink, T.R.D.J. Radstake

Read More....

Which Psoriasis Biologics Have the Best Response Rates?

2016-08-04T14:06:00.001-04:00

Dr Graeme Lipper reviews a retrospective observational study that sought to find out how long patients stayed on a biologic drug they were taking to treat psoriasis.
Medscape Dermatology

By

Read More....

The infliximab biosimilar in the treatment of moderate to severe plaque psoriasis

2016-07-27T13:53:00.001-04:00

The infliximab originator's patent recently expired, leading to the production of biosimilar versions of the drug. The biosimilars' efficacy was not tested on patients with psoriasis but most regulatory authorities approved their use in psoriasis because of an extrapolation of data from studies conducted in other diseases.

By Paolo Dapavo, Igor Vujic, Maria Teresa Fierro, Pietro Quaglino, Martina Sanlorenzo

Read More....

The Golden Ratio of Beauty—A Hidden Treasure

2016-07-26T16:26:00.001-04:00

Represented by the Greek letter φ, the golden ratio is characterized as an irrational number, approximately equal to 1.61803. It is often expressed through the division of a line into 2 parts, so that the proportion of the entire line to its longer part is equivalent to the ratio of the longer part to the shorter part. The Fibonacci sequence is another tool that may be used to derive the golden ratio. As the sequence is taken out to infinity, each integer may be divided by the preceding integer, yielding the same proportion.

By Mlacker S, Shah VV, Aldahan AS, et al.

Read More....

Diabetic Foot Ulcers, Vascular Problems Predict Death

2016-07-20T22:12:00.001-04:00

Lower limb vascular complications and foot ulcers are significant predictors of mortality in patients with diabetes, a new study shows, so physicians should be on the lookout for such symptoms.
Medscape Medical News

By

Read More....

Mosquito Protection: Is DEET the Best? What About the Rest?

2016-07-19T22:02:00.001-04:00

When a patient asks, "Which mosquito repellent should I use?" you can be ready to answer with these four CDC-recommended products.
Medscape Pediatrics

By

Read More....

There soon may be an imaging system under your skin

2016-07-01T23:12:00.001-04:00

Body:

Engineers at the University of Stuttgart in Germany have designed an “imaging system” so tiny that it can be sent straight into human tissue.

The system is based on a three-lens camera built using 3-D printing. The camera has a lens just 100 micrometers wide that can focus on images up to 3 millimeters away and relay them back through an optical fiber.

The Stuttgart team has published a report on their work in the journal Nature Photonics, and Phys.org has more info plus photos:

Topic:

Advanced Visualization

Author Reference:

Dave Pearson

Content Type:

Referenced Content

Top Story:

By David Pearson

Read More....

How often should you bathe your child with eczema? Daily 'soak and smear' or steer clear?

2016-06-30T16:00:00.001-04:00

If you have a child with newly-diagnosed eczema, you may be wondering how often you should bathe him. You are not alone.

By

Read More....

Modern Electronic Devices: An Increasingly Common Cause of Skin Disorders in Consumers

2016-05-14T19:37:00.001-04:00

The modern conveniences and enjoyment brought about by electronic devices bring with them some health concerns. In particular, personal electronic devices are responsible for rising cases of several skin disorders, including pressure, friction, contact dermatitis, and other physical dermatitis. The universal use of such devices, either for work or recreational purposes, will probably increase the occurrence of polymorphous skin manifestations over time. It is important for clinicians to consider electronics as potential sources of dermatological ailments, for proper patient management. We performed a literature review on skin disorders associated with the personal use of modern technology, including personal computers and laptops, personal computer accessories, mobile phones, tablets, video games, and consoles.

By Corazza, Monica; Minghetti, Sara; Bertoldi, Alberto Maria; Martina, Emanuela; Virgili, Annarosa; Borghi, Alessandro

Read More....

How to remove a splinter: American Academy of Dermatology provide some tips

2016-05-12T23:04:00.001-04:00

Everyone has been there. No sooner did you or your child touch that old wooden bench when a small sliver of wood slides into the skin - causing a surprising amount of pain.

By

Read More....

Brush up on anatomy to avoid filler complications

2016-05-10T18:58:00.001-04:00

Patient history and anatomy raise risk

By

Read More....

Conflicts of interest among academic dermatologists: freedom or constraint?

2016-05-08T08:41:00.003-04:00

Summary

Intangible and institutional conflicts of interest can particularly affect academia. Academic scientists have peculiar social responsibilities with respect to education and research. These responsibilities may conflict with the increased presence of industry in academia and commercialization of academic research through patents and royalties. Drug approval is almost entirely dependent worldwide on data produced in studies led by pharmaceutical industries. A reflection of the increasing role of the market in academic research is given by exaggerated claims in press releases by academic institutions. In consideration of the extensive presence of industry in academia, there is a need for a move from individual to institutional conflicts of interest disclosure, defining institutional policies for regulating conflicts of interest and developing an ‘ethically credible partnership’.

By L. Naldi

Read More....

Effect of Teledermatology on Access to Care in Medicaid

2016-05-08T08:41:00.001-04:00

This study of claims data from a large California Medicaid Managed care plan evaluates the effect of teledermatology on the number of patients who received dermatology care and describes which patients were most likely to be referred to teledermatology in a population of Medicaid enrollees.

By Uscher-Pines L, Malsberger R, Burgette L, et al.

Read More....

Regeneron, Sanofi Eczema Drug Clears Hurdles in Big Trials

2016-05-02T11:53:00.001-04:00

Regeneron Pharmaceuticals Inc and Sanofi said on Friday their experimental treatment for eczema proved highly effective in two large studies, without serious side effects often seen with standard treatments for the chronic inflammatory skin disease.
Reuters Health Information

By

Read More....

Truth: Recent Aging Research May Cause Confusion And Gray Hair

2016-04-22T12:39:00.001-04:00

Studies: You've got to love them. Just this week alone in the world of aging research, we learned that selfies can prematurely age your skin, sunbathing may actually be good for you, and older people who take the stairs are mentally sharper than those who wait for the elevator. Oh, and the debate was reignited over whether a nightly glass of wine is good for longevity. It's enough to make your head spin. Taking it from the top, and with a grain of salt that may or may not be good for those with hypertension: 1. Selfies cause wrinkles and age your skin. Yes, they can but no, they won't. A 26-year-old British blogger who takes at least 50 selfies a day consulted a dermatologist to see if the high-energy visible (HEV) light from her cellphone screen was causing her skin to age prematurely. Th...

MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.

By Science - The Huffington Post

Read More....