Research laboratory presentation

The Marín-Juez laboratory, at the CHU Sainte-Justine Research Center, is recruiting PhD students and postdoctoral fellows (up to 5 years fully funded position).  Our laboratory is interested in the cellular and molecular mechanisms regulating cardiac regeneration and development.  

The successful applicant will join the Marín-Juez laboratory at the CHU Sainte-Justine Research Center, where they will have access to state-of-the-art facilities and technology platforms including Advanced imaging platform (light-sheet, spinning-disc confocal, multiphoton, STED super-resolution, etc.), genomics (DropSeq, 10x, Illumina Novaseq, Visium), IPSC Cell Reprograming and bioinformatics platforms.  The CHU Sainte-Justine Research Center provides a thriving scientific environment where the successful applicant will have the opportunity to work with multidisciplinary scientific teams and to collaborate with talented clinicians and researchers. 

Research project description

We have previously uncovered mechanisms governing coronary network replenishment, including the formation of a vascular scaffold that supports cardiomyocyte regeneration and mediates coronary-epicardial interactions and immune responses (Marín-Juez et al., PNAS 2016; Marín-Juez et al., Dev Cell 2019; El-Sammak et al., Circ Res 2022; Wang et al., Development 2024; Gupta et al. Dev Bio 2025; Rouf et al. Development 2026). Our recent work identifies the epicardium as a master regulator of cardiac fibrosis resolution and tissue replenishment (Kayman-Kürekçi et al. NCVR2026).

Building on these findings, we now aim to elucidate how the cardiac endothelium, epicardium, and immune system components cooperate to regulate tissue replenishment, as well as the specific mechanisms underlying their roles in cardiomyocyte regeneration and development.

PhD student position 

Applicants should have training in molecular biology, cell biology, or related fields.  Candidates should be enthusiastic about regenerative and developmental biology. Previous research experience with zebrafish and/or heart regeneration is highly valued but not essential. Candidates with experience in confocal/light-sheet imaging and/or genome engineering are strongly encouraged to apply.

Postdoc position 

We are looking for candidates with a Ph.D. in the biological sciences and laboratory experience in tissue repair/regeneration, cellular, molecular biology, or genetics.  Previous experience working with zebrafish, imaging and histology are highly valued but not essential. Candidates with experience in confocal/light-sheet imaging and/or genome engineering are strongly encouraged to apply.  Preference will be given to applicants with excellent collaborative and communication skills.  

How to apply

Candidates must send the required documentsto Rubén Marín Juez at ruben.marin.juez.hsj@ssss.gouv.qc.ca

Please provide:

• Curriculum vitæ
• Cover letter 
• References (2 or 3)

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The laboratory of Assistant Professor Dr. Jette Lengefeld is inviting applications for a position as Laboratory Technician who is extensively experienced in experimental mouse work.

About the group
The Lengefeld laboratory is working on understanding how the failure to regenerate tissue with age is a major health issue. A contributor to this decline is the loss of stem cell function. Despite the essential role of stem cells, it is still unclear how they fail to maintain their functions during aging and disease. We discovered a new aspect of stem cell aging in vivo: cellular enlargement. With age and damage, stem cells increase in size causing their functional decline. However, we are only beginning to understand how size impacts stem cell fitness and the physiological importance of this process remains unsolved.

Laboratory website: http://lengefeldlab.com/

The position
This position includes several responsibilities. The main activities are listed below:

1. Supporting research projects of lab members, with a strong drive to intellectually contribute. Tasks will include mouse genotyping, mouse blood sampling, mouse monitoring and communication with mouse facility staff. We expect you to fully understand the experimental design and underlying reasons for performing the experiment.

2. Performing administrative tasks for group leader, research meetings and bills.

3. Active intellectual contribution to research discussions such as lab meetings, journal clubs, and project discussions.

Required qualifications and experience
– Extensive experience in experimental mouse work and authorization to work with mice is required (please do not apply if not applicable).

– Minimum required education: Master’s degree.

– Experience in hematology will be prioritized.

– The candidate must be fluent in English and Finnish language skills are an advantage.

– The candidate is collaborative, communicative, and comfortable working in an international and multidisciplinary environment.

Salary and contract
The position is offered for a fixed term of one year starting in May 2026 or as negotiated. Salary will depend upon the applicant’s level of skills, knowledge, and abilities and is based on the university salary system. A trial period of 6 months will be applied.

Interested?
Application should include the following documents: cover letter (max 1 page), CV of max. 4 pages, full publication list, and names of three references.

The deadline for the applications is 30.04.2026, but the positions will be filled immediately once suitable candidates have been identified.

Please submit your application, together with the required attachments, through the University of Helsinki electronic recruitment system by clicking the “Apply for the position” – link below. Internal applicants (i.e., current employees of the University of Helsinki) must submit their applications by logging in to the SAP system: https://msap.helsinki.fi. For technical support regarding the recruitment system, please contact rekrytointi@helsinki.fi.

If you have any questions about the position, please do not hesitate to contact postdoc Dr. Emilie Cerezo emilie.cerezo(at)helsinki.fi.

Link to apply: https://jobs.helsinki.fi/job/Helsinki-Laboratory-Technician%2C-group-Lengefeld/1356106757/

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We are a new lab helping to develop a slipper snail model (Crepidula atrasolea) to test fundamental evolution and development questions. As a member of our lab, you will have the freedom to tailor your project to your interests, ideally relating to the genetics, development, or role of the nervous system in shell formation in gastropods. Depending on your project and research goals, you will have the opportunity to learn microinjection, CRISPR, hybridization chain reaction in situ hybridization, immunohistochemistry, confocal microscopy, animal husbandry, electron microscopy, and more.

Please reach out to me with questions: nicole.webster@usask.ca

Start date: Fall 2026.

Required qualifications:
•Master’s degree in Biology, or equivalent in a relevant field
•Proof of English language proficiency may be required

Further information:
Website: https://artsandscience.usask.ca/profile/NWebster
Biology Graduate program: https://grad.usask.ca/programs/biology.php

We are a welcoming group that celebrates diverse backgrounds and strives for an inclusive environment for biologists of any background, age, race/ethnicity, sexual orientation, gender, or dis/ability.

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The post Postdoctoral Position to Study Cardiovascular Development appeared first on the Node.

The student will be engaged in computer programing to create a mathematical model and molecular work involving collecting tissue and RNA samples from fish and/or tunicates. Molecular work will involve collecting tissue and RNA samples and the student will have opportunity to learn RNA extraction, PCR, immunohistochemistry, HR and imaging analysis, under the guidance of Dr. Sato. In the computational work, the student will learn programming and simulation, but this requires experience and basic skills in programming using python and R.

Applicant eligibility: A female student who has Master’s degree or going to obtain Master’s degree in a relevant field of study, either in mathematical or computer science or biological sciences with a strong computational or bioinformatics component by the starting date of PhD. We are looking for motivated student interested in animal biology, developmental biology, programming with problem solving abilities as well as resilience to solve daily problems. Research experience in molecular biology and basic programming would be advantageous. This position is open to applications from all nationalities.

Application deadline: 1 June 2025 midnight JST, open until filled.

The studentship will start 01 October 2025 the earliest. Full time only.

For more details, please visit:

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PhD position in the Denholm lab at the University of Edinburgh, UK

You will use modern techniques to study the development and/or physiology of one of the most powerful water-conserving systems in nature – the beetle cryptonephridial (or ‘buried kidney’) complex.

Insects can live and thrive in some of the most inhospitable environments on earth, including extremely desiccating conditions such as deserts. Many species possess a powerful water-conserving system called the cryptonephridial (or ‘buried kidney’) complex (CNC), which recovers water from the rectum and recycles it back to the body. This remarkable system even allows water vapour absorption from moist air, providing a novel physiological mechanism for water uptake. It is estimated that >400,000 insect species have a CNC, with CNCs being particularly common in beetles. The broad principles underpinning CNC physiology were laid down half a century ago, and the system has since become a staple textbook example of a countercurrent exchange system. Despite this, next to nothing is known about CNC development, molecular physiology, endocrinological regulation or evolution. 

In this project you will use the model beetle species Tribolium and exploit enabling technologies including genomics, single-nuclei RNAseq, informatics, imaging and in-vivo analysis to identify how this system develops and functions. We have catalogued gene expression profiles (using snRNAseq) from the CNC of this species (in both embryo and adult), providing a window into its embryonic development and the molecular players involved in its physiological function at single-cell resolution. 

The techniques you will use and be trained in include: (1) Bioinformatics. You will use this to prioritise key genes involved in the development and function of the system. (2) Hybridisation chain reaction fluorescent in situ hybridisation. You will use this to map expression of candidate genes in embryonic, larval and adult CNCs. (3) Gene knock-down: you will use RNAi to knock-down gene activity for each candidate and, use (4) Microscopy (both fluorescence confocal and electron microscopy) and simple physiological assays to establish roles for these genes in CNC development and function.  

Results from this project will significantly expand our understanding of one of the most powerful water-conserving systems in nature, one that is fundamental to insect physiology, ecology and evolutionary success.

Please apply here: https://www.findaphd.com/phds/project/eastbio-exploring-form-and-function-in-one-of-nature-s-most-powerful-water-conservation-systems/?p179647

For more details please contact: Barry.Denholm@ed.ac.uk

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We seek to appoint a Lecturer (Assistant Prof Equivalent) in developmental, cell or stem cell biology, genetics or genomics with a focus on human disease modelling and/or craniofacial biology.

Who are you? You are a promising postdoc with an excellent publication profile, high-quality collaborative connections and ambitious plans for your independent research programme. You should be an early career scientists with an outstanding research track record and excellent potential to develop an internationally competitive research programme and to collaborate within the Centre and across King’s.

Who are we? The Centre for Craniofacial & Regenerative Biology at King’s College London is one of the leading centres for Craniofacial and Stem Cell Biology worldwide. Our Centre comprises 19 collaborative groups with interests in craniofacial and stem cell biology, innovative bioengineering strategies to regeneration and repair, and big data approaches to understand the complexity of development and disease. Our research spans basic, clinical and translational sciences. The Centre offers a vibrant, collaborative, and interactive research and teaching environment in the heart of London.

https://www.kcl.ac.uk/dentistry/research/centre-for-craniofacial-regenerative-biology

Successful candidates are expected to establish their independent research group in the Centre, to contribute to our educational programmes and to training the next generation of interdisciplinary scientists, and to support the strategic vision of the Centre and King’s. They will have access to a variety of PhD programmes, as well as mentorship and career development opportunities. They will work with outstanding scientists across King’s https://www.kcl.ac.uk/research and access our world-class Research Facilities: https://www.kcl.ac.uk/research/facilities

CLOSING DATE 6 October. Application link below. Informal inquiries are welcome to Head of Department Professor Andrea Streit or to relevant Faculty members.

https://rb.gy/ksftkv

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Our lab has expertise and interest in liver and brain biology and their associated diseases.

To this end, in the past years, we have developed 3D human organoid culture systems to grow mini-livers and mini-brains in a dish. We use these models together with state-of-the-art technologies such as for instance CRISPR-Cas9, to model different diseases, such as cancer and genetic disease, and to understand mechanisms underlining the pathogenesis as well as regulating proper organ development.

This PhD position is fully funded (4-years) by a recent grant from the Dutch cancer society (KWF). This project will deal with understanding how chronic liver disease develops into cancer. To read more about the project, visit the link below:

https://www.kwf.nl/nieuws/toekenningen-call-2024-1

To read more about our lab, please visit:

https://www.bendellab.com

An official post to apply will be opened soon on the institutional webpage, but for informal inquiries we appreciate if you can reach out to us both in a joint email, and reviewing of interesting candidates can start earlier:

Benedetta Artegiani: b.a.artegiani@prinsesmaximacentrum.nl

Delilah Hendriks: d.f.g.hendriks-7@prinsesmaximacentrum.nl

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How stem cells decide to choose between two conflicting fates, division vs. differentiation, is an unsolved mystery of stem cell biology. The overarching goal of Shariati lab is to determine the mechanisms that link cell division to cellular differentiation in pluripotent cells. We will combine emerging genome-editing technologies with single cell imaging to determine regulatory principles of cell fate decisions in pluripotent cells.

Applicants with demonstrated experience in any of the following areas are highly encouraged to apply: Stem Cell Biology, Transcription, Quantitative Single Cell imaging, CRISPR screening and Mouse Genetics. The potential start date is Fall 2023.

As your postdoc advisor, I will support you to reach the career goals that you set for yourself. In addition, UCSC has exceptional career development programs for postdoctoral fellows. Santa Cruz is a great town for postdocs as you can easily refresh your mind by strolling in beautiful redwood forests on campus or going to one of the many nearby beaches. Please email me (alish {a} ucsc.edu) a cover letter stating your scientific background and interest, your CV and names/addresses of your advisors.

Applicants from underrepresented groups in sciences are highly encouraged to apply. Informal inquires also are welcomed!  

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Postdoc positions are immediately available in Guillermo Oliver’s lab in downtown Chicago to work in different aspects related to functional roles of the mammalian lymphatic vasculature in organogenesis.

Information about some of our recent work can be found in these links:

https://www.jci.org/articles/view/140685/pdf

https://www.nature.com/articles/s41586-020-2998-xhttps://advances.sciencemag.org/content/7/18/eabe7359httos://www.cell.com/cell/fulltext/S0092-8674(20)30816-3

Highly motivated individuals who recently obtained a PhD. or MD degree and have a strong background in the use of mouse models, and molecular and developmental biology are encouraged to apply.

For information about our lab see:

http://labs.feinberg.northwestern.edu/oliver/

https://twitter.com/NU Lymphatics

Interested individuals should send their curriculum vitae, a brief description of their research interests, and the names of three references to:

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Our lab currently has different research lines ranging from muscle and heart development and the evolutionary impact of gene loss (see an example https://go.nature.com/3E83Lw8), as well as EcoEvoDevo investigations studying the genetic response of the defensome of marine embryos to environmental threats such as biotoxins produced by harmful algal blooms of diatoms in the context of global warming or the effect of noise contamination from human activities on embryo development of marine invertebrate species (see an example in https://go.nature.com/2O82VY8).

Our research focus on the study of the appendicularian tunicate specie Oikopleura dioica as our favourite animal model (see this “A day in our lab” post in the node https://thenode.biologists.com/day-life-oikopleura-lab/lablife/ and embryo microinjection, CRISPR, RNAi, DNAi, fluorescent and confocal imaging, RNAseq, ATACseq, population genomics and bioinformatics are among the techniques we use in our lab. Among candidate postdocs, experience in some of those techniques will positively considered, and specially candidates willing to develop new tools based on CRISPR, as well as candidates willing to develop single-cell omics approaches to Oikopleura dioica to address some of the topics we currently work in the lab or new questions that candidates might be interested.

For PhD, there are varios calls already open, so please contact us as soon as possible, since the dealine is very soon.

For POSTDOCS, there is a call for a 3-year position to be open next week (required to have defended the PhD between 1/1/2021 and 31/12/2022; 30.000 EUR/year), and some other calls are coming in the next moths, some including starting-grants.

CONTACT: Interested candidates, please send an email ASAP to Cristian Cañestro (canestro@ub.edu), including a brief letter of interest, a brief CV, including list of publications with their impact, and technical skills all together in ONE single pdf file.

More info please visit our web: http://goo.gl/0ZaDm0

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The Steinmetz group at the Sars Centre in Bergen (Norway) is looking for a bioinformatician with expertise in analysing high-throughput sequencing datasets (bulk, single-cell, ATAC-Seq). The project aims to characterise the transition from cellular quiescence to cell cycle re-entry, which is induced by re-feeding of starved animals, in the sea anemone Nematostella vectensis.
Application deadline is November 25th 2022.
Link for more information and to apply for the position: https://tinyurl.com/yc43x7mc

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Fully-funded PhD and Postdoc positions are available in The Zaidel-Bar Lab to study the regulation of the cytoskeleton during cell and tissue morphogenesis. We invite highly motivated students to apply.

The lab takes a multi-scale approach from single proteins to the organism and system level, using a variety of cutting-edge technologies, most notably advanced microscopy, both in organoids and in the nematode C. elegans. Its goal is to understand the molecular mechanisms cells and tissues employ to change shape, migrate, sense, and generate mechanical forces that are essential for embryonic development and go awry in many diseases.

The lab welcomes outstanding international students with a degree in life sciences or in quantitative sciences, with a passion for research and interest in the cytoskeleton. The lab provides full fellowships for all students and housing on campus is an option. Lectures and courses are in English. Ph.D. studies usually last 4 years. Postdocs will be hired on a yearly contract up to 5 years.

The Zaidel-Bar lab is located in Tel-Aviv University, which is the leading interdisciplinary research and teaching university in Israel. Importantly, the scientific environment is dynamic and collaborative, with state of the art facilities, and students will have numerous opportunities to meet, learn from, and collaborate with excellent scientists.

Tel-Aviv is the cultural and commercial heart of Israel. Situated on a beautiful coast of the Mediterranean Sea, it is a fun, young city that never sleeps, with great food and weather.

To apply: send your CV (including transcripts) and a cover letter detailing your research experience and interest to: zaidelbar@tauex.tau.ac.il. Review of applications will begin immediately, and positions will remain open until filled.

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