Darn, this looks good

... the best networking power innovations are the ones that help make the use of servers more efficient

 

When it comes to data centers, Jim Cramer is dumber than a bag of hammers.

I want one ... now to justify it

the computational design of ligand binding is not a solved problem and needs to be revisited

… if you really want to understand the detailed molecular interactions that make it go in a particular direction, make certain contacts, break other contacts, hydrolyze GTP, you know, form bonds, etcetera, and do it all amazingly accurately, then you do need a high resolution picture of those states. But, that’s not going to be enough. It’s going to take a lot of work by biochemists, by computational people who do molecular dynamics and things like that to really, eventually, understand it in the sense that we would understand, say, a more typical reaction.

Pasting SMILES strings wouldn't be a problem if chemists actually understood how to generate them and could do so with the same ease and accuracy as typing text into a Google search box, or if the extra work added tangible value. But this is not the case in the majority of situations. Few chemists really understand the SMILES syntax and fewer still can create SMILES de novo. Nor do they want to - and with good reason.

The flaw of synchronous communication has been repackaged as the boon of realtime communication. Asynchrony, once our friend, is now our enemy. The transaction costs of interpersonal communication have fallen below zero: It costs more to leave the stream than to stay in it. The approaching Wave promises us the best of both worlds: the realtime immediacy of the phone call with the easy broadcasting capacity of email. Which is also, as we'll no doubt come to discover, the worst of both worlds. Welcome to the conference call that never ends. Welcome to Wave hell.