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                    This study explored how health status influences residential mobility in Ontario, Canada, using data from 93,235 adults aged 25-64. Researchers found that individuals with poorer health were more likely to move to or remain in low-income neighborhoods compared to those with better health. Specifically, those with fair or poor health had higher odds of moving from low- to low-income neighborhoods, moving from high- to low-income neighborhoods, moving from low- to high-income neighborhoods, and not moving within low-income neighborhoods compared to not moving within high-income neighborhoods. The study used self-reported health and multimorbidity data, and results were consistent across different health measures. This suggests that health status significantly impacts residential mobility, contributing to socioeconomic gradients in neighborhoods.
                
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                <h4><a title="The Impact of Power Outages on Cardiovascular Hospitalizations Among Medicare Fee-for-service Enrollees in New York State, 2017–2018" href="https://journals.lww.com/epidem/abstract/2025/07000/the_impact_of_power_outages_on_cardiovascular.4.aspx?context=featuredarticles&amp;collectionid=1">The Impact of Power Outages on Cardiovascular Hospitalizations Among Medicare Fee-for-service Enrollees in New York State, 2017–2018</a></h4>
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                    36(4):458-466, July 2025.
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                    This study examined whether power outages lead to more hospitalizations for cardiovascular disease (CVD) among older adults in New York State. Researchers analyzed data from 245,452 Medicare beneficiaries aged 65 and older, focusing on 390,530 CVD hospitalizations. They compared periods with and without power outages using a case-crossover design, considering factors like urbanicity, season, age, sex, and socioeconomic status. Results showed no significant link between power outages and CVD hospitalizations, even in New York City. The study suggests that more research is needed, including looking at severe weather events and expanding the geographic scope.
                
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                <h4><a title="The Same but Different?: A Systematic Review of the Impact of Selection and Collider Bias on Internal Validity" href="https://journals.lww.com/epidem/abstract/2025/07000/the_same_but_different___a_systematic_review_of.6.aspx?context=featuredarticles&amp;collectionid=1">The Same but Different?: A Systematic Review of the Impact of Selection and Collider Bias on Internal Validity</a></h4>
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                    This study reviewed literature on selection and collider bias, which are threats to the internal validity of epidemiological studies. Researchers retained 33 articles and 12 textbooks for data abstraction, finding that collider bias is often seen as having minimal impact, while selection bias effects vary. Most collider bias sources evaluated bias under the sharp null (assuming no relationship between the exposure and outcome), which may limit understanding of its true impact. The study suggests that examining collider bias beyond this assumption and considering interactions between causes could enhance predictions and assessments of its effects on study validity. This highlights a need for more nuanced approaches to understanding these biases.
                
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                <h4><a title="Generalizing and Transporting Causal Inferences from Randomized Trials in the Presence of Trial Engagement Effects" href="https://journals.lww.com/epidem/abstract/2025/07000/generalizing_and_transporting_causal_inferences.9.aspx?context=featuredarticles&amp;collectionid=1">Generalizing and Transporting Causal Inferences from Randomized Trials in the Presence of Trial Engagement Effects</a></h4>
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                    This study explores how trial participation can affect outcomes beyond treatment effects, challenging the assumption that trial engagement effects are absent in generalizing trial results to broader populations. The authors introduce new methods to account for these effects, assuming no interaction between trial participation and treatment assignment. They demonstrate that even with trial engagement effects, trial data can be combined with population data to identify treatment effects in real-world settings. This approach offers a fresh perspective on existing methods for generalizing trial results, especially when trial engagement effects are suspected but interactions are minimal.
                
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                    This study explored how missing data from participants who skip study visits might affect mortality estimates in two large HIV studies. Researchers found that not censoring data after two missed visits showed a 10-year mortality rate of 23% in the MACS study and 21% in the WIHS study. When data was censored after missed visits, mortality estimates were slightly lower by up to 5%. Using statistical methods to adjust for missing data helped correct this bias. Overall, censoring did not significantly change mortality estimates, especially when adjustments were applied.
                
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                <h4><a title="State-level Payday Loan Bans and Preterm Births in the US, 2000–2019" href="https://journals.lww.com/epidem/abstract/2025/07000/state_level_payday_loan_bans_and_preterm_births_in.13.aspx?context=featuredarticles&amp;collectionid=1">State-level Payday Loan Bans and Preterm Births in the US, 2000–2019</a></h4>
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                    36(4):541-550, July 2025.
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                    This study explored whether limiting payday loans, known for high interest rates and potential financial strain, could reduce preterm births, a major cause of infant mortality in the US. Researchers analyzed data from 2000 to 2019, focusing on states that imposed payday loan restrictions. Using a difference-in-difference approach, they found that states with restrictions saw a decrease in preterm births by 0.22 per 100 live births within three years, equating to 4512 fewer preterm births than expected. The findings suggest that payday loan restrictions may positively impact public health by reducing preterm births.
                
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                <h4><a title="Time and Age as Longitudinal Timescales: Multiple Useful Models are Illuminating" href="https://journals.lww.com/epidem/fulltext/2025/07000/time_and_age_as_longitudinal_timescales__multiple.16.aspx?context=featuredarticles&amp;collectionid=1">Time and Age as Longitudinal Timescales: Multiple Useful Models are Illuminating</a></h4>
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                    36(4):572-579, July 2025.
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                <h4><a title="Alcohol Policy in Adolescence and Subsequent Alcohol-attributable Hospitalizations and Mortality at Ages 21−54 Years: A Register-based Cohort Study" href="https://journals.lww.com/epidem/fulltext/2025/07000/alcohol_policy_in_adolescence_and_subsequent.17.aspx?context=featuredarticles&amp;collectionid=1">Alcohol Policy in Adolescence and Subsequent Alcohol-attributable Hospitalizations and Mortality at Ages 21−54 Years: A Register-based Cohort Study</a></h4>
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                    This study examined how exposure to stricter alcohol policies during adolescence affects later health outcomes. Using Finnish data from birth cohorts 1950-1964, researchers found that men who were aged 19-25 during the 1975-1977 alcohol policy reforms had similar rates of alcohol-related hospitalizations and mortality compared to those who were of legal drinking age. However, men who were underage at the time of the reform had incrementally lower rates of alcohol-related hospitalizations and mortality cohort by cohort. For instance, men aged 17 at the time had a hazard ratio of 0.91 for hospitalization, while those aged 13 had a ratio of 0.85. The results suggest that stricter alcohol policies during adolescence can lead to reduced alcohol-related health issues in adulthood.
                
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                    Reproductive complications, like gestational diabetes, often recur in subsequent pregnancies, posing a challenge in predicting risks due to varying pregnancy histories among women. This study introduces a new method, the Beta Approach for Risk Summarization (BARS), to estimate the likelihood of gestational diabetes using retrospective data from the Sister Study cohort. BARS is used to predict subsequent occurrences of gestational diabetes based on updated pregnancy histories. The calibration of the predictive model for gestational diabetes was assessed and demonstrated to work well. The method was then applied to prospective data from the Sister Study to revisit an earlier paper linking gestational diabetes to breast cancer risk, using BARS and additional person time, offering a refined approach to understanding reproductive health risks.
                
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                    This study examined the health impacts of smoke PM2.5, a pollutant from wildfires, on hospitalization rates for cardiovascular and respiratory diseases across 15 U.S. states from 2006 to 2016. Using hospitalization records and smoke PM2.5 data, researchers found that exposure over three months increased hospitalization risks for various diseases, with hypertension showing the highest risk increase. Effects persisted up to three months post-exposure, especially in areas with higher deprivation or vegetation, and among ever-smokers. These findings highlight the prolonged health risks of wildfire smoke, emphasizing the need for public health strategies to mitigate these effects.
                
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                <h4><a title="Early Detection of Dengue Outbreaks: Transmission Model Analysis of a Dengue Outbreak in a Remote Setting in Ecuador" href="https://journals.lww.com/epidem/abstract/2025/09000/early_detection_of_dengue_outbreaks__transmission.6.aspx">Early Detection of Dengue Outbreaks: Transmission Model Analysis of a Dengue Outbreak in a Remote Setting in Ecuador</a></h4>
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                    36(5):636-645, September 2025.
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                    This study examined a 2019 dengue outbreak in Ecuador to determine when the first infection likely occurred, using a hidden Markov model. Despite the outbreak being detected in mid-May, the analysis suggests the virus was circulating as early as February, with the primary case likely between 7 and 12 February. This indicates the virus was present for about 3 months before the outbreak was recognized. The findings highlight the importance of surveillance systems that can detect low-level transmission early, allowing for timely interventions to reduce the spread and impact of infectious diseases like dengue.
                
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                    This study introduces a new framework for analyzing how exposure affects outcomes through multiple mediators, called separable path-specific effects. Unlike traditional methods, which rely on complex and unverifiable assumptions, this approach offers a clearer understanding by breaking down the causal effects into separate components. The framework is based on a model that allows for verification of assumptions in future experiments, making it more reliable. It also helps identify issues like confounders and incorrect mediator order. Overall, this method provides a more interpretable and testable way to study causal mediation with multiple mediators.
                
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                    36(5):e21-e23, September 2025.
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